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The enzyme appears in viruses and cellular organisms
Synonyms
Decarboxylase, orsellinate,
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Decarboxylase, orsellinate
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orsellinate = orcinol + CO2
orsellinate = orcinol + CO2
mechanism
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orsellinate = orcinol + CO2
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2,4-dihydroxy-6-methylbenzoate carboxy-lyase (orcinol-forming)
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2,4-Dihydroxy-5,6-dimethylbenzoic acid
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2,4-Dihydroxy-6-ethyl benzoic acid
Orcinol monoethylether
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2,4-Dihydroxy-6-methylbenzoate
1,3-Dihydroxy-5-methylbenzene + CO2
3-Chloro-2,4-dihydroxy-6-methylbenzoate
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4-methoxy-2-hydroxy-6-methyl benzoic acid
homoorcinol + CO2
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5-Chloro-2,4-dihydroxy-6-methylbenzoate
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2,4-Dihydroxy-6-methylbenzoate
1,3-Dihydroxy-5-methylbenzene + CO2
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i.e. orsellinic acid, , ir
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2,4-Dihydroxy-6-methylbenzoate
1,3-Dihydroxy-5-methylbenzene + CO2
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additional information
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no requirement
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2,3-Dihydroxybenzoate
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2,5-Dihydroxybenzoate
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2-Hydroxy-6-methylbenzoate
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Salicylic acid derivatives
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2,4-Dihydroxybenzoate
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2,4-Dihydroxybenzoate
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0.211 - 0.26
2,4-dihydroxy-6-methylbenzoate
0.211
2,4-dihydroxy-6-methylbenzoate
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0.26
2,4-dihydroxy-6-methylbenzoate
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7.5
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activity decreases above pH 7.5
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brenda
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brenda
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72000
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1 * 72000, SDS-PAGE
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monomer
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1 * 72000, SDS-PAGE
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3
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complete loss of activity after 30 min
4727
7.5
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remains stable at
4726
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25
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inactivated after several h
55
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no loss of activity after 10 min, up to 55°C
65
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rapidly inactivated above
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no loss of activity after dialysis
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-15°C, little loss of activity after several months
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no loss of activity when stored frozen for several months
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Mosbach, K.; Schultz, J.
Studies on lichen enzymes: Purification and properties of orsellinate decarboxylase obtained from Lasallia pustulata
Eur. J. Biochem.
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485-488
1971
Lasallia pustulata
brenda
Petterson, G.
An orsellinic acid decarboxylase isolated from Gliocladium roseum
Acta Chem. Scand.
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2013-2021
1965
Clonostachys rosea
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brenda
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4.1.1.58 orsellinate decarboxylase
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