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Reference on EC 4.1.1.50 - adenosylmethionine decarboxylase and Organism(s) Homo sapiens

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
White Tabor, C.; Tabor, H.
Methionine adenosyltransferase (S-adenosylmethionine synthetase) and S-adenosylmethionine decarboxylase
Adv. Enzymol. Relat. Areas Mol. Biol.
56
251-282
1984
Bos taurus, Saccharomyces cerevisiae, Escherichia coli, Homo sapiens, Lytechinus pictus, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Manni, A.; Badger, B.; Grove, R.; Kunselman, S.; Demers, L.
Isolation and characterization of human breast cancer cell overexpressing S-adenosylmethionine decarboxylase
Cancer Lett.
95
23-28
1995
Homo sapiens
Manually annotated by BRENDA team
Shantz, L.M.; Stanley, B.A.; Secrist III, J.A.; Pegg, A.E.
Purification of human S-adenosylmethionine decarboxylase expressed in Escherichia coli and use of this protein to investigate the mechanism of inhibition by the irreversible inhibitors, 5'-deoxy-5'-[(3-hydrazinopropyl)methylamino]adenosine and 5'-[[(Z)-4-amino-2-butenyl]methylamino]-5'-deoxyadenosine
Biochemistry
31
6848-6855
1992
Homo sapiens
Manually annotated by BRENDA team
Regenass, U.; Caravatti, G.; Mett, M.; Stanek, J.; Schneider, P.; Mueller, M.; Matter, A.; Vertino, P.; Porter, C.W.
New S-adenosylmethionine decarboxylase inhibitors with potent antitumor activity
Cancer Res.
52
4712-4718
1992
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Regenass, U.; Mett, H.; Stanek, J.; Mueller, M.; Kramer, D.; Porter, C.W.
CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity
Cancer Res.
54
3210-3217
1994
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
White, E.L.; Arnett, G.; Secrist III, J.A.; Shannon, W.M.
Characterization of S-adenosylmethionine decarboxylase induced by human cytomegalovirus infection
Virus Res.
31
255-263
1994
Homo sapiens
Manually annotated by BRENDA team
Xiong, H.; Stanley, B.A.; Pegg, A.E.
Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase
Biochemistry
38
2462-2470
1999
Homo sapiens
Manually annotated by BRENDA team
Tolbert, W.D.; Ekstrom, J.L.; Mathews, II; Secrist, J.A., 3rd; Kapoor, P.; Pegg, A.E.; Ealick, S.E.
The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase
Biochemistry
40
9484-9494
2001
Homo sapiens (P17707), Homo sapiens
Manually annotated by BRENDA team
Ndjonka, D.; Zou, Y.; Bi, X.; Woster, P.; Walter, R.D.; Luersen, K.
The activator-binding site of Onchocerca volvulus S-adenosylmethionine decarboxylase, a potential drug target
Biol. Chem.
384
1195-1201
2003
Homo sapiens, Onchocerca volvulus
Manually annotated by BRENDA team
Nummela, P.; Yin, M.; Kielosto, M.; Leaner, V.; Birrer, M.J.; Holtta, E.
Thymosin beta4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylase-transfected fibroblasts
Cancer Res.
66
701-712
2006
Homo sapiens
Manually annotated by BRENDA team
Greco, A.; Calle, A.; Morfin, F.; Thouvenot, D.; Cayre, M.; Kindbeiter, K.; Martin, L.; Levillain, O.; Diaz, J.J.
S-adenosyl methionine decarboxylase activity is required for the outcome of herpes simplex virus type 1 infection and represents a new potential therapeutic target
FASEB J.
19
1128-1130
2005
Homo sapiens
Manually annotated by BRENDA team
Lam, K.; Zhang, L.; Bewick, M.; Lafrenie, R.M.
HSG cells differentiated by culture on extracellular matrix involves induction of S-adenosylmethione decarboxylase and ornithine decarboxylase
J. Cell. Physiol.
203
353-361
2005
Homo sapiens
Manually annotated by BRENDA team
Tian, H.; Liu, X.; Zhang, B.; Sun, Q.; Sun, D.
Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase inhibits lung cancer cell growth
Acta Biochim. Biophys. Sin.
39
423-430
2007
Homo sapiens
Manually annotated by BRENDA team
Kim, J.S.; Kim, T.L.; Kim, K.C.; Choe, C.; Chung, H.W.; Cho, E.W.; Kim, I.G.
S-Adenosylmethionine decarboxylase partially regulates cell growth of HL-60 cells by controlling the intracellular ROS level: Early senescence and sensitization to gamma-radiation
Arch. Biochem. Biophys.
456
58-70
2006
Homo sapiens (P17707)
Manually annotated by BRENDA team
Gong, L.; Zhang, B.; Zhang, Y.; Hu, H.; Zhao, Z.; Liu, X.
Cloning, expression and purification of human S-adenosylmethionine decarboxylase gene alpha subunit
Chin. J. Physiol.
50
29-33
2007
Homo sapiens
Manually annotated by BRENDA team
Gong, L.; Jiang, C.; Zhang, B.; Hu, H.; Wang, W.; Liu, X.
Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase induces G1 arrest in HT-29 cells
J. Biochem. Mol. Biol.
39
730-736
2006
Homo sapiens
Manually annotated by BRENDA team
Brooks, W.H.; McCloskey, D.E.; Daniel, K.G.; Ealick, S.E.; Secrist, J.A.; Waud, W.R.; Pegg, A.E.; Guida, W.C.
In silico chemical library screening and experimental validation of a novel 9-aminoacridine based lead-inhibitor of human S-adenosylmethionine decarboxylase
J. Chem. Inf. Model.
47
1897-1905
2007
Homo sapiens (P17707), Homo sapiens
Manually annotated by BRENDA team
Bale, S.; Ealick, S.E.
Structural biology of S-adenosylmethionine decarboxylase
Amino Acids
38
451-460
2010
Trypanosoma brucei, Aquifex aeolicus (O66615), Aquifex aeolicus, Homo sapiens (P17707), Homo sapiens, Solanum tuberosum (Q04694), Solanum tuberosum, Thermotoga maritima (Q9WZC3), Thermotoga maritima
Manually annotated by BRENDA team
Barker, R.H.; Liu, H.; Hirth, B.; Celatka, C.A.; Fitzpatrick, R.; Xiang, Y.; Willert, E.K.; Phillips, M.A.; Kaiser, M.; Bacchi, C.J.; Rodriguez, A.; Yarlett, N.; Klinger, J.D.; Sybertz, E.
Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis
Antimicrob. Agents Chemother.
53
2052-2058
2009
Homo sapiens, Trypanosoma brucei
Manually annotated by BRENDA team
Hyvoenen, M.T.; Howard, M.T.; Anderson, C.B.; Grigorenko, N.; Khomutov, A.R.; Vepsaelaeinen, J.; Alhonen, L.; Jaenne, J.; Keinaenen, T.A.
Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues
Biochem. J.
422
321-328
2009
Homo sapiens
Manually annotated by BRENDA team
Bale, S.; Brooks, W.; Hanes, J.W.; Mahesan, A.M.; Guida, W.C.; Ealick, S.E.
Role of the sulfonium center in determining the ligand specificity of human S-adenosylmethionine decarboxylase
Biochemistry
48
6423-6430
2009
Homo sapiens (P17707), Homo sapiens
Manually annotated by BRENDA team
Pegg, A.E.
S-Adenosylmethionine decarboxylase
Essays Biochem.
46
25-45
2009
Bacillus subtilis, Saccharomyces cerevisiae, Catharanthus roseus, Clostridium acetobutylicum, Escherichia coli, Homo sapiens, Methanocaldococcus jannaschii, Solanum tuberosum, Thermotoga maritima, Trypanosoma brucei, Trypanosoma cruzi
Manually annotated by BRENDA team
McCloskey, D.E.; Bale, S.; Secrist, J.A.; Tiwari, A.; Moss, T.H.; Valiyaveettil, J.; Brooks, W.H.; Guida, W.C.; Pegg, A.E.; Ealick, S.E.
New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: Studies of adenine C8 substitution in structural analogues of S-adenosylmethionine
J. Med. Chem.
52
1388-1407
2009
Homo sapiens (P17707), Homo sapiens
Manually annotated by BRENDA team
Koomoa, D.L.; Borsics, T.; Feith, D.J.; Coleman, C.C.; Wallick, C.J.; Gamper, I.; Pegg, A.E.; Bachmann, A.S.
Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma
Mol. Cancer Ther.
8
2067-2075
2009
Homo sapiens
Manually annotated by BRENDA team
Paasinen-Sohns, A.; Kaeaeriaeinen, E.; Yin, M.; Jaervinen, K.; Nummela, P.; Hoelttae, E.
Chaotic neovascularization induced by aggressive fibrosarcoma cells overexpressing S-adenosylmethionine decarboxylase
Int. J. Biochem. Cell Biol.
43
441-454
2011
Homo sapiens
Manually annotated by BRENDA team
Liao, C.; Wang, Y.; Tan, X.; Sun, L.; Liu, S.
Discovery of novel inhibitors of human S-adenosylmethionine decarboxylase based on in silico high-throughput screening and a non-radioactive enzymatic assay
Sci. Rep.
5
10754
2015
Homo sapiens
Manually annotated by BRENDA team