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Information on EC 4.1.1.31 - phosphoenolpyruvate carboxylase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC4.1.1.31

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IUBMB Comments

This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle when operating in the reverse direction. The reaction proceeds in two steps: formation of carboxyphosphate and the enolate form of pyruvate, followed by carboxylation of the enolate and release of phosphate.

The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
pepck, phosphoenolpyruvate carboxykinase, pepc, phosphoenolpyruvate carboxylase, pepcase, pep carboxylase, c4 pepc, pepc1, phosphoenol pyruvate carboxylase, pep-carboxylase, more

SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Carboxylase, phosphopyruvate (phosphate)
-
-
-
-
CP21
-
-
-
-
CP28
-
-
-
-
CP46
-
-
-
-
PEP carboxylase
-
-
-
-
PEPC
-
-
-
-
PEPCase
-
-
-
-
Phosphoenolpyruvate carboxylase
Phosphoenolpyruvic carboxylase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
carboxylation
-
-
-
-
decarboxylation
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
C4 photosynthetic carbon assimilation cycle, NAD-ME type, C4 photosynthetic carbon assimilation cycle, NADP-ME type, C4 photosynthetic carbon assimilation cycle, PEPCK type, CO2 fixation into oxaloacetate (anaplerotic), ethene biosynthesis V (engineered), formaldehyde assimilation I (serine pathway), gluconeogenesis II (Methanobacterium thermoautotrophicum), Methanobacterium thermoautotrophicum biosynthetic metabolism, mixed acid fermentation, nitrogen remobilization from senescing leaves, partial TCA cycle (obligate autotrophs)
SYSTEMATIC NAME
IUBMB Comments
phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)
This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle when operating in the reverse direction. The reaction proceeds in two steps: formation of carboxyphosphate and the enolate form of pyruvate, followed by carboxylation of the enolate and release of phosphate.
CAS REGISTRY NUMBER
COMMENTARY hide
9067-77-0
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
phosphoenolpyruvate + HCO3-
phosphate + oxaloacetate
show the reaction diagram
-
Substrates: -
Products: -
r
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.002
-
in a coupled assay with malate dehydrogenase
top print hide Go to Organism Search
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
soil-isolate
-
-
Manually annotated by BRENDA team
Highest Expressing Human Cell Lines
Cell Line Links Gene Links
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A080VTQ1_PSEAI
878
0
97840
TrEMBL
-
A0A8G7ATY4_PSEAI
878
0
97721
TrEMBL
-
A0A8F9JKY7_PSEAI
878
0
97838
TrEMBL
-
A0A8F8WKM2_PSEAI
878
0
97895
TrEMBL
-
A0A8G7B1V6_PSEAI
878
0
97741
TrEMBL
-
A0A8G4HXD7_PSEAI
878
0
97896
TrEMBL
-
A0A3S3UAY9_PSEAI
878
0
97842
TrEMBL
-
A0A8G2VPC9_PSEAI
878
0
97815
TrEMBL
-
A0A8G2R014_PSEAI
878
0
97831
TrEMBL
-
A0A2R3IQP0_PSEAI
878
0
97733
TrEMBL
-
A0A844NGV3_PSEAI
878
0
97872
TrEMBL
-
A0A8G5NR71_PSEAI
878
0
97810
TrEMBL
-
A0A8G5UI00_PSEAI
878
0
97896
TrEMBL
-
A0A8G4MX86_PSEAI
878
0
97811
TrEMBL
-
A0A8B5ALC3_PSEAI
878
0
97899
TrEMBL
-
A0A8G2KLT8_PSEAI
878
0
97937
TrEMBL
-
A0A8G4GGI7_PSEAI
878
0
97884
TrEMBL
-
A0A8G1VGF6_PSEAI
878
0
97826
TrEMBL
-
A0A2R4KQQ7_PSEAI
878
0
97845
TrEMBL
-
A0A509JJI8_PSEAI
878
0
97812
TrEMBL
-
A0A8G5RK76_PSEAI
878
0
97896
TrEMBL
-
A0A2C9WXD5_PSEAI
878
0
97845
TrEMBL
-
A0A5E5R8A2_PSEAI
878
0
97815
TrEMBL
-
A0A8G6A6N9_PSEAI
878
0
97840
TrEMBL
-
A0A7M3AXA8_PSEAI
878
0
97856
TrEMBL
-
A0A8G4LX58_PSEAI
867
0
96813
TrEMBL
-
A0A8G6J8E4_PSEAI
878
0
97840
TrEMBL
-
A0A8G2KFI8_PSEAI
878
0
97838
TrEMBL
-
A0A8G2ZFJ6_PSEAI
878
0
97876
TrEMBL
-
A0A8G4AI61_PSEAI
878
0
97787
TrEMBL
-
A0A6A9JXJ9_PSEAI
878
0
97893
TrEMBL
-
A0A8G7TI36_PSEAI
878
0
97877
TrEMBL
-
A0A8G3UTY9_PSEAI
878
0
97874
TrEMBL
-
A0A8G7HXJ5_PSEAI
878
0
97856
TrEMBL
-
A0A8B5BK70_PSEAI
878
0
97812
TrEMBL
-
A0A8G4YYY7_PSEAI
878
0
97856
TrEMBL
-
A0A8G2XWR8_PSEAI
878
0
97835
TrEMBL
-
A0A8G5I3F9_PSEAI
878
0
97867
TrEMBL
-
A0A3P3HZU9_PSEAI
878
0
97868
TrEMBL
-
A0A8G5J929_PSEAI
878
0
97787
TrEMBL
-
A0A8G3VXK8_PSEAI
878
0
97898
TrEMBL
-
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Buch, A.; Archana, G.; Naresh Kumar, G.
Metabolic channeling of glucose towards gluconate in phosphate-solubilizing Pseudomonas aeruginosa P4 under phosphorus deficiency
Res. Microbiol.
159
635-642
2008
Pseudomonas aeruginosa, Pseudomonas fluorescens, Pseudomonas aeruginosa P4
Manually annotated by BRENDA team