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Information on EC 3.8.1.6 - 4-chlorobenzoate dehalogenase

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EC Tree
     3 Hydrolases
         3.8 Acting on halide bonds
             3.8.1 In carbon-halide compounds
                3.8.1.6 4-chlorobenzoate dehalogenase
IUBMB Comments
Catalyses the first step in the degradation of chlorobenzoate in Pseudomonas. In many microorganisms, this activity comprises three separate enzymes, EC 6.2.1.33 (4-chlorobenzoate---CoA ligase), EC 3.8.1.7 (4-chlorobenzoyl-CoA dehalogenase) and EC 3.1.2.23 (4-hydroxybenzoyl-CoA thioesterase).
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The enzyme appears in viruses and cellular organisms
Synonyms
FcbB, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride
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