Reference on EC 3.7.1.8 - 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Omori, T.; Sugimura, K.; Ishigooka, H.; Minoda, Y.
Purification and some propertiees of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl
Agric. Biol. Chem.
50
931-937
1986
Pseudomonas cruciviae, Pseudomonas cruciviae S93 B1
-
Buenz, P.V.; Falchetto, R.; Cook, A.M.
Purification of two isofunctional hydrolases (EC 3.7.1.8) in the degradative pathway for dibenzofuran in Sphingomonas sp. strain RW1
Biodegradation
4
171-178
1993
Sphingomonas sp., Sphingomonas sp. RW1
Ahmad, S.; Fraser, J.; Sylvestre, M.; Larose, A.; Khan, A.; Bergeron, J.; Juteau, J.M.; Sondossi, M.
Sequence of the bphD gene encoding 2-hydroxy-6-oxo-(phenylchlorophenyl) hexa-2,4-dienoic acid (HOP/cPCA) hydrolase involved in the biphenyl/polychlorinated biphenyl degradation pathway in Comamonas testosteroni: evidence suggesting involvement of Ser112 in catalytic activity
Gene
156
69-74
1995
Comamonas testosteroni (Q59324)
Kim, E.; Kim, Y.; Kim, C.K.
Genetic structures of the genes encoding 2,3-dihydroxybiphenyl 1,2-dioxygenase and 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase from biphenyl- and 4-chlorobiphenyl-degrading Pseudomonas sp. strain DJ-12
Appl. Environ. Microbiol.
62
262-265
1996
Pseudomonas sp., Pseudomonas sp. DJ-12
Lau, P.C.K.; Garnon, J.; Labbe, D.; Wang, Y.
Location and sequence analysis of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase-encoding gene (bpdF) of the biphenyl polychlorinated biphenyl degradation pathway in Rhodococcus sp. M5
Gene
171
53-57
1996
Rhodococcus sp.
Horsman, G.P.; Ke, J.; Dai, S.; Seah, S.Y.; Bolin, J.T.; Eltis, L.D.
Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway
Biochemistry
45
11071-11086
2006
Paraburkholderia xenovorans
Li, J.J.; Li, C.; Blindauer, C.A.; Bugg, T.D.
Evidence for a gem-diol reaction intermediate in bacterial C-C hydrolase enzymes BphD and MhpC from 13C NMR spectroscopy
Biochemistry
45
12461-12469
2006
Escherichia coli, Paraburkholderia xenovorans
Li, C.; Li, J.J.; Montgomery, M.G.; Wood, S.P.; Bugg, T.D.
Catalytic role for arginine 188 in the C-C hydrolase catalytic mechanism for Escherichia coli MhpC and Burkholderia xenovorans LB400 BphD
Biochemistry
45
12470-12479
2006
Escherichia coli, Paraburkholderia xenovorans
Speare, D.M.; Olf, P.; Bugg, T.D.
Hammett analysis of a C-C hydrolase-catalysed reaction using synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates
Chem. Commun. (Camb. )
2002
2304-2305
2002
Pseudomonas sp., Pseudomonas sp. LB400
Seah, S.Y.; Labbe, G.; Kaschabek, S.R.; Reifenrath, F.; Reineke, W.; Eltis, L.D.
Comparative specificities of two evolutionarily divergent hydrolases involved in microbial degradation of polychlorinated biphenyls
J. Bacteriol.
183
1511-1516
2001
Rhodococcus globerulus, Rhodococcus globerulus P6
Seah, S.Y.; Labbe, G.; Nerdinger, S.; Johnson, M.R.; Snieckus, V.; Eltis, L.D.
Identification of a serine hydrolase as a key determinant in the microbial degradation of polychlorinated biphenyls
J. Biol. Chem.
275
15701-15708
2000
Burkholderia cepacia, Burkholderia cepacia LB400
Lim, J.; Lee, J.; Lim, J.; Min, K.R.; Kim, C.; Kim, Y.
Characterization of the pcbD gene encoding 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Pseudomonas sp. P20
J. Microbiol. Biotechnol.
10
258-263
2000
Pseudomonas sp., Pseudomonas sp. P20
-
Nandhagopal, N.; Yamada, A.; Hatta, T.; Masai, E.; Fukuda, M.; Mitsui, Y.; Senda, T.
Crystal structure of 2-hydroxyl-6-oxo-6-phenylhexa-2,4-dienoic acid (HPDA) hydrolase (BphD enzyme) from the Rhodococcus sp. strain RHA1 of the PCB degradation pathway
J. Mol. Biol.
309
1139-1151
2001
Rhodococcus sp. (Q9KWQ6), Rhodococcus sp., Rhodococcus sp. RHA1 (Q9KWQ6)
Mukerjee-Dhar, G.; Shimura, M.; Miyazawa, D.; Kimbara, K.; Hatta, T.
bph genes of the thermophilic PCB degrader, Bacillus sp. JF8: characterization of the divergent ring-hydroxylating dioxygenase and hydrolase genes upstream of the Mn-dependent BphC
Microbiology
151
4139-4151
2005
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) JF8
Speare, D.M.; Fleming, S.M.; Beckett, M.N.; Li, J.J.; Bugg, T.D.
Synthetic 6-aryl-2-hydroxy-6-ketohexa-2,4-dienoic acid substrates for C-C hydrolase BphD: investigation of a general base catalytic mechanism
Org. Biomol. Chem.
2
2942-2950
2004
Pseudomonas sp., Pseudomonas sp. LB400
Riddle, R.R.; Gibbs, P.R.; Willson, R.C.; Benedik, M.J.
Purification and properties of 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic acid hydrolase involved in microbial degradation of carbazole
Protein Expr. Purif.
28
182-189
2003
Pseudomonas sp., Pseudomonas sp. LD2
Lack, N.; Yam, K.; Lowe, E.; Horsman, G.; Owen, R.; Sim, E.; Eltis, L.
Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism
J. Biol. Chem.
285
434-443
2010
Mycobacterium tuberculosis (P9WNH5), Mycobacterium tuberculosis H37Rv (P9WNH5)
Ruzzini, A.C.; Horsman, G.P.; Eltis, L.D.
The catalytic serine of MCP hydrolases is activated differently for C-O bond cleavage than for C-C bond cleavage
Biochemistry
51
5831-5840
2012
Paraburkholderia xenovorans
Ruzzini, A.C.; Ghosh, S.; Horsman, G.P.; Foster, L.J.; Bolin, J.T.; Eltis, L.D.
Identification of an acyl-enzyme intermediate in a meta-cleavage product hydrolase reveals the versatility of the catalytic triad
J. Am. Chem. Soc.
134
4615-4624
2012
Paraburkholderia xenovorans (P47229)
Kohler, H.P.; Schmid, A.; van der Maarel, M.
Metabolism of 2,2'-dihydroxybiphenyl by Pseudomonas sp. strain HBP1: production and consumption of 2,2',3-trihydroxybiphenyl
J. Bacteriol.
175
1621-8
1993
Pseudomonas sp., Pseudomonas sp. HBP1
Siirola, E.; Frank, A.; Grogan, G.; Kroutil, W.
C-C hydrolases for biocatalysis
Adv. Synth. Catal.
355
1677-1691
2013
Paraburkholderia xenovorans (P47229), Rhodococcus sp. (Q75WN8), Rhodococcus sp. RHA1 (Q75WN8)
-
Zhou, H.; Qu, Y.; Kong, C.; Shen, E.; Wang, J.; Zhang, X.; Ma, Q.; Zhou, J.
The key role of a non-active-site residue Met148 on the catalytic efficiency of meta-cleavage product hydrolase BphD
Appl. Microbiol. Biotechnol.
97
10399-10411
2013
Dyella ginsengisoli (B5SU85), Dyella ginsengisoli LA-4 (B5SU85)
Li, Y.; Zhang, R.; Du, L.; Zhang, Q.; Wang, W.
Insight into the catalytic mechanism of meta-cleavage product hydrolase BphD: a quantum mechanics/molecular mechanics study
RSC Adv.
5
66591-66597
2015
Paraburkholderia xenovorans
-
Kuatsjah, E.; Chan, A.; Hurst, T.; Snieckus, V.; Murphy, M.; Eltis, L.
Metal- and serine-dependent meta-cleavage product hydrolases utilize similar nucleophile-activation strategies
ACS Catal.
8
11622-11632
2018
Sphingobium sp. SYK-6 (G2IN02)
-
Jia, Y.; Wang, J.; Ren, C.; Nahurira, R.; Khokhar, I.; Wang, J.; Fan, S.; Yan, Y.
Identification and characterization of a meta-cleavage product hydrolase involved in biphenyl degradation from Arthrobacter sp. YC-RL1
Appl. Microbiol. Biotechnol.
103
6825-6836
2019
Arthrobacter sp. YC-RL1 (A0A0H0ZQK0)
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