Disease on EC 3.6.1.56 - 2-hydroxy-dATP diphosphatase
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2-hydroxy-datp diphosphatase deficiency
hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage.
Adenoma
HMTH1 induces the metastasis and recurrence of the parotid adenoma by repairing DNA damage.
Alzheimer Disease
Expression of hMTH1 in the hippocampi of control and Alzheimer's disease.
Brain Neoplasms
Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors.
Brain Neoplasms
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Breast Neoplasms
Biological characterisation and application of human MTH1 and monoclonal antibody preparation.
Breast Neoplasms
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Carcinoma
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Carcinoma
Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma: evidence of persistent oxidative stress in cancer.
Carcinoma, Hepatocellular
Expression of DNA repair enzyme hMTH1 mRNA and protein in hepatocellular carcinoma.
Carcinoma, Hepatocellular
[Potential role of human DNA-repair enzymes hMTH1, hOGG1 and hMYHalpha in the hepatocarcinogenesis]
Carcinoma, Non-Small-Cell Lung
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Carcinoma, Non-Small-Cell Lung
Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer.
Carcinoma, Renal Cell
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Colorectal Neoplasms
Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1, in hereditary nonpoliposis colorectal cancer.
Colorectal Neoplasms
The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells.
Colorectal Neoplasms, Hereditary Nonpolyposis
Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1, in hereditary nonpoliposis colorectal cancer.
Diabetes Mellitus, Type 2
Combined analysis of polymorphism variants in hMTH1, hOGG1 and MUTYH genes on the risk of type 2 diabetes in the Chinese population.
Dystonia
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.
Glioma
Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors.
Huntington Disease
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.
Idiopathic Pulmonary Fibrosis
Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias.
Leukemia
Inhibition of 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity of the antimutagenic human MTH1 protein by nucleoside 5'-diphosphates.
Lung Diseases, Interstitial
Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias.
Lung Neoplasms
Contribution of hMTH1 to the maintenance of 8-oxoguanine levels in lung DNA of non-small-cell lung cancer patients.
Lung Neoplasms
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Lung Neoplasms
Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer.
Lung Neoplasms
Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells.
Lymphatic Metastasis
Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer.
Meningioma
Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors.
Neoplasm Metastasis
Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer.
Neoplasm Metastasis
HMTH1 induces the metastasis and recurrence of the parotid adenoma by repairing DNA damage.
Neoplasm Metastasis
hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells.
Neoplasms
A variant form of hMTH1, a human homologue of the E coli mutT gene, correlates with somatic mutation in the p53 tumour suppressor gene in gastric cancer patients.
Neoplasms
Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors.
Neoplasms
Bacterial DNA repair genes and their eukaryotic homologues: 2. Role of bacterial mutator gene homologues in human disease. Overview of nucleotide pool sanitization and mismatch repair systems.
Neoplasms
Contribution of hMTH1 to the maintenance of 8-oxoguanine levels in lung DNA of non-small-cell lung cancer patients.
Neoplasms
Expression of DNA repair enzyme hMTH1 mRNA and protein in hepatocellular carcinoma.
Neoplasms
Frequent microsatellite instabilities and analyses of the related genes in familial gastric cancers.
Neoplasms
Hexabromocyclododecane-induced Genotoxicity in Cultured Human Breast Cells through DNA Damage.
Neoplasms
hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage.
Neoplasms
hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells.
Neoplasms
hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia.
Neoplasms
Inhibitory Effect of 8-Halogenated 7-Deaza-2'-deoxyguanosine Triphosphates on Human 8-Oxo-2'-deoxyguanosine Triphosphatase, hMTH1, Activities.
Neoplasms
Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma: evidence of persistent oxidative stress in cancer.
Neoplasms
Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1, in hereditary nonpoliposis colorectal cancer.
Neoplasms
Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity.
Neoplasms, Neuroepithelial
Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors.
Neurilemmoma
Accumulation of 8-oxo-2'-deoxyguanosine and increased expression of hMTH1 protein in brain tumors.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia.
Stomach Neoplasms
A variant form of hMTH1, a human homologue of the E coli mutT gene, correlates with somatic mutation in the p53 tumour suppressor gene in gastric cancer patients.
Thyroid Neoplasms
hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage.
Thyroid Neoplasms
hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells.
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