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Information on EC 3.6.1.55 - 8-oxo-dGTP diphosphatase and Organism(s) Pseudomonas aeruginosa

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EC Tree
     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.55 8-oxo-dGTP diphosphatase
IUBMB Comments
This enzyme hydrolyses the phosphoanhydride bond between the alpha and beta phosphate of 8-oxoguanine-containing nucleoside di- and triphosphates thereby preventing misincorporation of the oxidized purine nucleoside triphosphates into DNA. It does not hydrolyse 2-hydroxy-dATP (cf. EC 3.6.1.56, 2-hydroxy-dATP diphosphatase) . Requires Mg2+.
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This record set is specific for:
Pseudomonas aeruginosa
Word Map
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
Synonyms
7,8-dihydro-8-oxo-dGTP pyrophosphohydrolase, 8-oxo-dGTP diphosphatase, AK369000, CiMutT, MTH1, MuT, MutT, MutT homologue 1, Nudix hydrolase, NUDT1, more
PATHWAY SOURCE
PATHWAYS
SYSTEMATIC NAME
IUBMB Comments
8-oxo-dGTP diphosphohydrolase
This enzyme hydrolyses the phosphoanhydride bond between the alpha and beta phosphate of 8-oxoguanine-containing nucleoside di- and triphosphates thereby preventing misincorporation of the oxidized purine nucleoside triphosphates into DNA. It does not hydrolyse 2-hydroxy-dATP (cf. EC 3.6.1.56, 2-hydroxy-dATP diphosphatase) [4]. Requires Mg2+.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
Sequence
A0A485G5B8_PSEAI
315
0
34041
TrEMBL
A0A485CSK3_PSEAI
315
0
34053
TrEMBL
A0A485HVI8_PSEAI
316
0
34500
TrEMBL
A0A4U9R4H9_PSEAI
315
0
34041
TrEMBL
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