Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 3.6.1.25 - triphosphatase

Please use the Disease Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Achlorhydria
Helicobacter pylori CagL Activates ADAM17 to Induce Repression of the Gastric H, K-ATPase alpha Subunit.
Alkalosis
Mechanism of alkalosis-induced constriction of rat cerebral penetrating arterioles.
Alzheimer Disease
Defense mechanism to oxidative DNA damage in glial cells.
Protective effects of melatonin on mitochondrial biogenesis and mitochondrial structure and function in the HEK293-APPswe cell model of Alzheimer's disease.
Anemia
Inosine triphosphate pyrophosphohydrolase activity: more accurate predictor for ribavirin-induced anemia in hepatitis C infected patients than ITPA genotype.
The Levels of Sera Malondialdehyde, Erythrocyte Membrane Na+-K+/Mg++ and Ca++/Mg++ Adenosine 5' Triphosphatase in Patients with Sickle Cell Anemia.
[Inosine triphosphatase gene polymorphism and ribavirin-related anemia in chronic hepatitis C patients].
[Studies on renal anemias. 3. The behavior of the phosphoric esters of adenosine and adenosine triphosphatase of the erythrocytes in hyperazotemic states]
Anemia, Hemolytic
[Experimental hemolytic anemia induced by hetero-antisera. I. Behavior of the adenosine triphosphatase activity of erythrocytes.]
Anemia, Pernicious
Localization of a pernicious anaemia autoantibody epitope on the alpha-subunit of human H,K-adenosine triphosphatase.
Parietal cell antibodies in pernicious anemia inhibit H+, K+-adenosine triphosphatase, the proton pump of the stomach.
Positive correlation between H,K-adenosine triphosphatase autoantibodies and Helicobacter pylori antibodies in patients with pernicious anemia.
Anemia, Sickle Cell
The Levels of Sera Malondialdehyde, Erythrocyte Membrane Na+-K+/Mg++ and Ca++/Mg++ Adenosine 5' Triphosphatase in Patients with Sickle Cell Anemia.
Arachnoid Cysts
Fluid secretion in arachnoid cysts as a clue to cerebrospinal fluid absorption at the arachnoid granulation.
Arrhythmias, Cardiac
Acylated Kaempferol Glycosides from Laurus nobilis Leaves and Their Inhibitory Effects on Na(+)/K(+)-Adenosine Triphosphatase.
Arteriosclerosis
[Studies on arteriosclerosis and endangitis obliterans. VIII. Hexokinase and adenosine triphosphatase in skeletal muscles in peripheral vascular disorders.]
Arthritis, Rheumatoid
Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis.
Blindness
The effect of glucose and calcium on Ca2+-adenosine triphosphatase in pancreatic islets isolated from a normal and a non-insulin-dependent diabetes mellitus rat model.
Blister
Cell motility through plasma membrane blebbing.
Brain Edema
Studies on experimental cerebral edema. I. Modification of glial triphosphatase activity in cerebral edema of the cat.
Brain Neoplasms
Defense mechanism to oxidative DNA damage in glial cells.
Breast Neoplasms
Enhanced expression of the 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase gene in human breast tumor cells.
Carcinogenesis
Alterations in the expression of uvomorulin and Na+,K(+)-adenosine triphosphatase during mouse skin tumor progression.
Carcinoma
Alterations in Na+, K+ and Ca2+ transport in erythrocytes of patients with carcinomas of the head and neck: possible role of mild anaemia and cell age.
Alterations in the expression of uvomorulin and Na+,K(+)-adenosine triphosphatase during mouse skin tumor progression.
Characterization of ecto-nucleoside triphosphatase on A-431 human epidermoidal carcinoma cells.
Role of the Na+, K(+)-adenosine triphosphatase in the accumulation of cis-diamminedichloroplatinum(II) in human ovarian carcinoma cells.
Carcinoma, Hepatocellular
Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.
Mitochondrial ATPase of Zajdela hepatoma. II. Mitochondria of Zajdela hepatoma contain less adenosine triphosphatase than mitochondria of rat liver.
SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice.
Carcinoma, Squamous Cell
Alterations in the expression of uvomorulin and Na+,K(+)-adenosine triphosphatase during mouse skin tumor progression.
The antiproliferative riminophenazine agents clofazimine and b669 promote lysophospholipid-mediated inhibition of na+, k+-adenosine triphosphatase-activity in cancer cell-lines in-vitro.
Cardiomyopathy, Dilated
Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
Cardiotoxicity
Cardiac sodium, potassium-adenosine triphosphatase as a possible site of adriamycin-induced cardiotoxicity.
Effect of an aminocardenolide and digoxin upon atrioventricular refractory period in the dog.
Cataract
In vitro production of steroid cataract in bovine lens. Part II: measurement of sodium-potassium adenosine triphosphatase activity.
Cholestasis
Intravenous ursodeoxycholic acid reduces cholestasis in parenterally fed newborn piglets.
Colorectal Neoplasms
CHD1L promotes tumor progression and predicts survival in colorectal carcinoma.
Cystic Fibrosis
Calcium and sodium transport processes in patients with cystic fibrosis. I. A specific decrease in Mg2+-dependent, Ca2+-adenosine triphosphatase activity in erythrocyte membranes from cystic fibrosis patients.
Phosphoinositide content of erythrocyte membranes in cystic fibrosis.
Cysts
Epithelial polarity and differentiation in polycystic kidney disease.
Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.
Demyelinating Diseases
Changes in the distribution of a calcium-dependent ATPase during demyelination and remyelination in the central nervous system.
Dengue
Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations.
Dermatitis
Langerhans cells in the immunopathology of contact allergic dermatitis.
Diabetes Mellitus
Modifications induced by plasma from insulin-dependent diabetic patients and by lysophosphatidylcholine on human Na+,K(+)-adenosine triphosphatase.
The effects of captopril and losartan on erythrocyte membrane Na+/K(+)-ATPase activity in experimental diabetes mellitus.
Diabetes Mellitus, Type 1
Modifications induced by insulin-dependent diabetes mellitus on human placental Na+/K+-adenosine triphosphatase.
Diabetes Mellitus, Type 2
The effect of glucose and calcium on Ca2+-adenosine triphosphatase in pancreatic islets isolated from a normal and a non-insulin-dependent diabetes mellitus rat model.
Diabetes, Gestational
Sialic acid content in erythrocyte membranes from pregnant women affected by gestational diabetes.
Diabetic Neuropathies
A combination of the aldose reductase inhibitor, statil, and the prostaglandin E1 analogue, OP1206.alpha CD, completely improves sciatic motor nerve conduction velocity in streptozocin-induced chronically diabetic rats.
Drug-Related Side Effects and Adverse Reactions
Personalized Whole-Cell Kinetic Models of Metabolism for Discovery in Genomics and Pharmacodynamics.
Essential Hypertension
Discordant segregation of Na+,K(+)-adenosine triphosphatase alleles and essential hypertension.
Erythrocyte calcium-stimulated, magnesium-activated adenosine 5'-triphosphatase activity in essential hypertension.
Na-K-adenosine triphosphatase and cation content in the erythrocyte in essential hypertension.
Platelet membrane calmodulin-stimulated calcium-adenosine triphosphatase. Altered activity in essential hypertension.
Problems and pitfalls in the isolation of an endogenous Na+, K+-ATPase inhibitor.
The role of endogenous Na+, K(+)-adenosine triphosphatase inhibitory factor in the regulation of membrane fluidity of erythrocytes in essential hypertension.
[Various properties of the Na+, K(+)-ATPase and the Mg (2+)-ATPase in erythrocytes from normotensive and hypertensive subjects]
Fanconi Syndrome
Silicon nephropathy.
Ganglion Cysts
[Effect of Alternanthera philoxeroides on enzymic histochemistry of oncomelania hupensis]
Gastritis
A conserved epitope on H+,K(+)-adenosine triphosphatase of parietal cells discerned by a murine gastritogenic T-cell clone.
A possible involvement of Fas-Fas ligand signaling in the pathogenesis of murine autoimmune gastritis.
H(+),K(+)-atpase (proton pump) is the target autoantigen of Th1-type cytotoxic T cells in autoimmune gastritis.
Human gastric H,K-adenosine triphosphatase beta-subunit is a major autoantigen in atrophic corpus gastritis. Expression of the recombinant human glycoprotein in insect cells.
Neonatal injection of native proton pump antigens induces autoimmune gastritis in mice.
Positive correlation between H,K-adenosine triphosphatase autoantibodies and Helicobacter pylori antibodies in patients with pernicious anemia.
[Billroth II.Surgery of the stomach]
Gastroesophageal Reflux
Proton pump inhibitor-induced Sweet's syndrome: report of acute febrile neutrophilic dermatosis in a woman with recurrent breast cancer.
[Clinical pharmacological aspects of the proton pump inhibitor therapy: importance of pharmacogenetic differences in the clinical practice]
Heart Diseases
Acylated Kaempferol Glycosides from Laurus nobilis Leaves and Their Inhibitory Effects on Na(+)/K(+)-Adenosine Triphosphatase.
Heart Failure
Acylated Kaempferol Glycosides from Laurus nobilis Leaves and Their Inhibitory Effects on Na(+)/K(+)-Adenosine Triphosphatase.
Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
[Effects of valsartan on sarcoplasmic reticulum calcium adenodine triphosphatase, protein kinase A and protein phosphatase 1 alpha in a rabbit model of heart failure]
Hepatitis
Altered lipid composition and differential changes in activities of membrane-bound enzymes of erythrocytes in hepatic cirrhosis.
Hepatitis C
Analysis of aptamer binding site for HCV-NS3 protease by alanine scanning mutagenesis.
C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity.
Hepatitis C, Chronic
[Inosine triphosphatase gene polymorphism and ribavirin-related anemia in chronic hepatitis C patients].
Herpes Simplex
Control of expression of the herpes simplex virus-induced deoxypyrimidine triphosphatase in cells infected with mutants of herpes simplex virus types 1 and 2 and intertypic recombinants.
Deoxyribopyrimidine triphosphatase activity specific for cells infected with herpes simplex virus type 1.
Induction of nuclear deoxyribopyrimidine triphosphatase and sensitivity of clinical isolates of herpes simplex virus to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
The herpes simplex virus type I origin binding protein. DNA-dependent nucleoside triphosphatase activity.
Hyperglycemia
Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2.
Hypersensitivity
Implications of altered Na+, K(+)-adenosine triphosphatase in allergy.
Hypertension
Implications of altered Na+-K+-adenosine triphosphatase in hypertension accompanying early stage kidney disease.
Isoform-specific modulation of Na+, K+-ATPase alpha-subunit gene expression in hypertension.
OASIS-HT: design of a pharmacogenomic dose-finding study.
Platelet membrane calmodulin-stimulated calcium-adenosine triphosphatase. Altered activity in essential hypertension.
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
Salt sensitivity and systemic hypertension in the elderly.
The maternal diet during pregnancy programs altered expression of the glucocorticoid receptor and type 2 11beta-hydroxysteroid dehydrogenase: potential molecular mechanisms underlying the programming of hypertension in utero.
The role of endogenous Na+, K(+)-adenosine triphosphatase inhibitory factor in the regulation of membrane fluidity of erythrocytes in essential hypertension.
[Na+--K+-adenosine triphosphatase and some oxidoreductases in the kidney of rats with spontaneous hypertension]
Hypertension, Malignant
Altered cations and muscle membrane ATPase activity in deoxycorticosterone acetate-salt spontaneously hypertensive rats.
Hypertension, Pregnancy-Induced
Sodium/potassium-adenosine triphosphatase on erythrocyte ghosts from pregnant women and its relationship to pregnancy-induced hypertension.
Hypertension, Renal
Na-K-adenosine triphosphatase in the kidney of rats with renal hypertension and spontaneously hypertensive rats.
Hyperthyroidism
Erythrocyte sodium fluxes, ouabain binding sites, and Na+,K(+)-ATPase activity in hyperthyroidism.
Platelet Na,K-adenosine triphosphatase as a tissue marker of hyperthyroidism.
Hypokalemia
Distal renal tubular acidosis and the potassium enigma.
Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase.
Interaction of the sympathetic nervous system and electrolytes in congestive heart failure.
Thyrotoxic Hypokalemic Periodic Paralysis.
Hyponatremia
Endometrial Na+, K+-ATPase pump function and vasopressin levels during hysteroscopic surgery in patients pretreated with GnRH agonist.
Hypothyroidism
Time course of the in vivo effects of thyroid hormone on cardiac gene expression.
Hypoxia-Ischemia, Brain
Transient hypoxia-ischemia in rats: changes in diffusion-sensitive MR imaging findings, extracellular space, and Na+-K+ -adenosine triphosphatase and cytochrome oxidase activity.
Infections
Control of expression of the herpes simplex virus-induced deoxypyrimidine triphosphatase in cells infected with mutants of herpes simplex virus types 1 and 2 and intertypic recombinants.
Deoxyribopyrimidine triphosphatase activity specific for cells infected with herpes simplex virus type 1.
H+/K+-adenosine triphosphatase mRNA in gastric fundic gland mucosa in patients infected with Helicobacter pylori.
Helicobacter pylori CagL Activates ADAM17 to Induce Repression of the Gastric H, K-ATPase alpha Subunit.
How Helicobacter pylori infection controls gastric acid secretion.
Schistosoma mansoni: fine structural localization of tegumental adenosine triphosphatases.
Insulin Resistance
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
Kidney Diseases
Implications of altered Na+-K+-adenosine triphosphatase in hypertension accompanying early stage kidney disease.
Leukemia
Cytoprotection against merocyanine 540-sensitized photoinactivation of the Na+,K(+)-adenosine triphosphatase in leukemia cells: glutathione and selenoperoxidase involvement.
Liver Cirrhosis
Altered lipid composition and differential changes in activities of membrane-bound enzymes of erythrocytes in hepatic cirrhosis.
Liver Neoplasms, Experimental
Kinetic properties of mitochondrial H+-adenosine triphosphatase in Morris hepatoma 3924A.
Long QT Syndrome
The cardiac K+ channel KCNQ1 is essential for gastric acid secretion.
Lupus Erythematosus, Systemic
Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis.
Luteoma
Alterations in intracellular messengers mobilized by gonadotropin-releasing hormone in an experimental ovarian tumor.
Malaria
Characterization of the mRNA capping apparatus of the microsporidian parasite Encephalitozoon cuniculi.
Trypanosoma brucei RNA triphosphatase. Antiprotozoal drug target and guide to eukaryotic phylogeny.
Malnutrition
Calcium signaling triggered by ouabain protects the embryonic kidney from adverse developmental programming.
Effect of malnutrition on (Na+ -K+ -Mg2+)-adenosine triphosphatase in developing rat brain.
Effects of neonatal undernutrition and subsequent nutritional rehabilitation or administration of thyroxine and hydrocortisone on the inositol phosphatase activities in rat intestine.
Effects of postweaning protein malnutrition on intestinal inositol phosphatase activities in normally weaned and neonatally undernourished rats.
Muscle Cramp
Muscle phosphoglycerate mutase deficiency with tubular aggregates: effect of dantrolene.
Muscular Diseases
Myopathy caused by a deficiency of Ca2+-adenosine triphosphatase in sarcoplasmic reticulum (Brody's disease).
Neoplasm Metastasis
The role of RhoC in ovarian epithelial carcinoma: A marker for carcinogenesis, progression, prognosis, and target therapy.
Neoplasms
A Screen for Novel Phosphoinositide 3-kinase Effector Proteins.
Alterations in the expression of uvomorulin and Na+,K(+)-adenosine triphosphatase during mouse skin tumor progression.
Does a higher ratio of serum calcium to magnesium increase the risk for postmenopausal breast cancer?
Ecto-enzymes of mammary gland and its tumours. Ca2+- or Mg2+-stimulated adenosine triphosphatase and its perturbation by concanavalin A.
F1-adenosine triphosphatase displays properties characteristic of an antigen presentation molecule for Vgamma9Vdelta2 T cells.
Gastric adenocarcinoma of fundic gland mucosa type localized in the submucosa: A case report.
Isolation and characterization of plasma membranes from transplantable human astrocytoma, oat cell carcinoma, and melanomas.
Membrane glycoprotein differences between normal lactating mammary tissue and the R3230 AC mammary tumor.
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Oncocytic adenocarcinoma of the stomach: parietal cell carcinoma.
PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase.
Protective Effects of Alpha-Lipoic Acid on Methotrexate-Induced Oxidative Lung Injury in Rats.
Purine-Metabolising Enzymes and Apoptosis in Cancer.
Rapidly Growing Papillary Well-Differentiated Adenocarcinoma in a Patient With a Helicobacter pylori-Naive Gastric Mucosa.
The role of RhoC in ovarian epithelial carcinoma: A marker for carcinogenesis, progression, prognosis, and target therapy.
nucleotide diphosphatase deficiency
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
Obesity
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
Optic Atrophy, Autosomal Dominant
Sericin improves heart and liver mitochondrial architecture in hypercholesterolaemic rats and maintains pancreatic and adrenal cell biosynthesis.
Osteopetrosis
Novel mutations in the a3 subunit of vacuolar H(+)-adenosine triphosphatase in a Japanese patient with infantile malignant osteopetrosis.
Papilloma
Alterations in the expression of uvomorulin and Na+,K(+)-adenosine triphosphatase during mouse skin tumor progression.
Paramyxoviridae Infections
Adenosine triphosphate phosphoydrolase activity associated with purified parainfluenza type 3 virions.
Parkinson Disease
A valine to methionine polymorphism at codon 83 in the 8-oxo-dGTPase gene MTH1 is not associated with sporadic Parkinson's disease.
Peptic Ulcer
Efficacy of the H+/K+-adenosine triphosphatase inhibitor omeprazole in peptic ulcer.
Lessons from two cases of anaphylaxis to proton pump inhibitors.
Peripheral Nervous System Diseases
Impaired rodent vagal nerve sodium-potassium-ATPase activity in streptozotocin diabetes.
phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) deficiency
Muscle phosphoglycerate mutase deficiency with tubular aggregates: effect of dantrolene.
Polycystic Kidney Diseases
Epithelial polarity and differentiation in polycystic kidney disease.
Polycystic Kidney, Autosomal Recessive
Epithelial polarity and differentiation in polycystic kidney disease.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Rapidly Growing Papillary Well-Differentiated Adenocarcinoma in a Patient With a Helicobacter pylori-Naive Gastric Mucosa.
Protein Deficiency
Effects of neonatal undernutrition and subsequent nutritional rehabilitation or administration of thyroxine and hydrocortisone on the inositol phosphatase activities in rat intestine.
Pulmonary Disease, Chronic Obstructive
Vastus lateralis Na(+)-K(+)-ATPase activity, protein, and isoform distribution in chronic obstructive pulmonary disease.
Pulmonary Edema
Sodium tanshinone iia sulfonate attenuates seawater aspiration-induced acute pulmonary edema by up-regulating Na(+),K(+)-ATPase activity.
Pyloric Stenosis, Hypertrophic
Gastroduodenal disorders in children.
Renal Insufficiency
Biochemical abnormalities of platelets in renal failure. Evidence for decreased platelet serotonin, adenosine diphosphate and Mg-dependent adenosine triphosphatase.
Rinderpest
The RNA triphosphatase domain of L protein of Rinderpest virus exhibits pyrophosphatase and tripolyphosphatase activities.
Sarcoma, Kaposi
HISTOCHEMISTRY OF KAPOSI'S SARCOMA. II. CHOLINESTERASES, MONOAMINE OXIDASE, AND ADENOSINE TRIPHOSPHATASE.
Seizures
An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT1A and Dopamine Pathway Activation as Potential Therapies.
The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster.
Sepsis
Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis.
Shock, Septic
Increased aerobic glycolysis through beta2 stimulation is a common mechanism involved in lactate formation during shock states.
Spinal Cord Injuries
Effect of thyrotropin-releasing hormone on Na(+)-K(+)-Adenosine triphosphatase activity following experimental spinal cord trauma.
Starvation
[Na,K-ATPase activity of erythrocytes of rats during prolonged starvation].
Stomach Ulcer
H+/K+-adenosine triphosphatase inhibitors. A new approach to the treatment of acid-peptic diseases.
Subarachnoid Hemorrhage
Changes in Ca(++)-ATPase activity in smooth-muscle cell membranes of the canine basilar artery with experimental subarachnoid hemorrhage.
Tachycardia
Effect of an aminocardenolide and digoxin upon atrioventricular refractory period in the dog.
triphosphatase deficiency
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
Ecto-adenosine triphosphatase deficiency in cultured human T and null leukemic lymphocytes. A biochemical basis for thymidine sensitivity.
Ureteral Obstruction
Unilateral Ureteral Obstruction Alters Expression of Acid-Base Transporters in Rat Kidney.
Vaccinia
A yeast-based genetic system for functional analysis of viral mRNA capping enzymes.
Characterization of the vaccinia virus RNA 5'-triphosphatase and nucleotide triphosphate phosphohydrolase activities. Demonstrate that both activities are carried out at the same active site.
Mapping the active site of vaccinia virus RNA triphosphatase.
Modification of the 5' end of mRNA. Association of RNA triphosphatase with the RNA guanylyltransferase-RNA (guanine-7-)methyltransferase complex from vaccinia virus.
Phylogeny of mRNA capping enzymes.
Structure-function analysis of the triphosphatase component of vaccinia virus mRNA capping enzyme.
The LEF-4 subunit of baculovirus RNA polymerase has RNA 5'-triphosphatase and ATPase activities.
Vaccinia virus RNA helicase: an essential enzyme related to the DE-H family of RNA-dependent NTPases.