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The expected taxonomic range for this enzyme is: Sus scrofa
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3.6.1.20
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microtubule
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microtubule-severing
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spindle
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disassembly
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mitosis
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aaa
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centrosome
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pole
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spastin
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flagella
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interphase
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p60-katanin
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mt-severing
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axonemal
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gamma-tubulin
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katnb1
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katanin-mediated
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microtubule-binding
Synonyms
5-phosphoadenosine hydrolase, acyl 5'-nucleotidase, more
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5-phosphoadenosine hydrolase
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acyl 5'-nucleotidase
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5'-acylphosphoadenosine + H2O = AMP + a carboxylate
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phosphorous acid anhydride hydrolysis
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5'-acylphosphoadenosine acylhydrolase
Also acts on inosine and uridine compounds.
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5'-acylphosphoadenosine + H2O
AMP + carboxylate
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acetyl adenylate + H2O
acetic acid + AMP
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benzoyl adenylate + H2O
benzoic acid + AMP
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hippuryl adenylate + H2O
hippuric acid + AMP
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inosine 5'-phosphobutyrate + H2O
butyric acid + IMP
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n-butyryl adenylate + H2O
n-butanoic acid + AMP
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uridine 5'-phosphobutyrate + H2O
butyric acid + UMP
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5'-acylphosphoadenosine + H2O
AMP + carboxylate
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adenylic acid
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50 mM causes 20% inhibition
iodoacetate
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inhibitory above 10 mM
p-chloromercuribenzoate
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inhibitory above 0.1 mM
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6.6
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in 0.1 M potassium phosphate
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brenda
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brenda
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brenda
Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
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-18°C, stable for months, 30% loss of activity by frequent freezing and thawing within 2 month
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Kellerman, G.M.
Isolation and characteristics of the enzyme acyl 5'-nucleotidase
Biochim. Biophys. Acta
33
101-105
1959
Sus scrofa
brenda
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