Disease on EC 3.6.1.11 - exopolyphosphatase

Please use the Disease Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Infections

Catalytic properties of wheat phytase that favorably degrades long-chain inorganic polyphosphate.

Leukemia

Inorganic polyphosphate in human osteoblast-like cells.

Polyphosphate Is a Novel Pro-inflammatory Regulator of Mast Cells and Is Located in Acidocalcisomes.

Neoplasm Metastasis

Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase.

Neoplasms

h-Prune is associated with poor prognosis and epithelial-mesenchymal transition in patients with colorectal liver metastases.

Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness.

Sepsis

Bacterial polyphosphates interfere with the innate host defense to infection.

Starvation

Functional Insights Into the Role of gppA in (p)ppGpp Metabolism of Vibrio cholerae.

Requirement of the exopolyphosphatase gene for cellular acclimation to phosphorus starvation in a cyanobacterium, Synechocystis sp. PCC 6803.

Tuberculosis

Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis.

Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis.

Polyphosphate deficiency affects the sliding motility and biofilm formation of Mycobacterium smegmatis.

The role of the novel exopolyphosphatase MT0516 in Mycobacterium tuberculosis drug tolerance and persistence.

The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities.

[Progress in polyphosphate and related metabolizing enzymes].