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Specificity varies with the source and with the activating metal ion. The enzyme from some sources may be identical with EC 18.104.22.168 (alkaline phosphatase) or EC 22.214.171.124 (glucose-6-phosphatase). A form of this enzyme with a molecular mass of about 90 kDa is found in tonoplasts of plants and fungi, where it imports protons from the cytosol into the vacuolar lumen.