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Information on EC 3.5.3.7 - guanidinobutyrase

for references in articles please use BRENDA:EC3.5.3.7

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IUBMB Comments

Requires Mn2+. Also acts, very slowly, on 5-guanidinopentanoate and 6-guanidinohexanoate.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
gbase, guanidinobutyrase, g-base, 4-guanidinobutyrase, gamma-guanidinobutyrate amidinohydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-guanidinobutanoate + H2O = 4-aminobutanoate + urea
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-arginine degradation IX (arginine:pyruvate transaminase pathway), L-arginine degradation VIII (arginine oxidase pathway), L-arginine degradation X (arginine monooxygenase pathway), L-arginine degradation XI, L-arginine degradation XII
Highest Expressing Human Cell Lines
Cell Line Links Gene Links