Reference on EC 3.5.2.9 - 5-oxoprolinase (ATP-hydrolysing) and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Van Der Werf, P.; Stephani, R.A.; Meister, A.
Accumulation of 5-oxoproline in mouse tissues after inhibition of 5-oxoprolinase and administration of amino acids: Evidence for function of the gamma-glutamyl cycle
Proc. Natl. Acad. Sci. USA
71
1026-1029
1974
Homo sapiens, Mus musculus, Pseudomonas sp., Rattus norvegicus
Van Der Werf, P.; Stephani, R.A.; Orlowski, M.; Meister, A.
Inhibition of 5-oxoprolinase by 2-imidazolidone-4-carboxylic acid
Proc. Natl. Acad. Sci. USA
70
759-761
1973
Homo sapiens, Mus musculus, Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Van Der Werf, P.; Orlowski, M.; Meister, A.
Enzymatic conversion of 5-oxo-L-proline (L-pyrrolidone carboxylate) to L-glutamate coupled with cleavage of adenosine triphosphate to adenosine diphosphate, a reaction in the gamma-glutamyl cycle
Proc. Natl. Acad. Sci. USA
68
2982-2985
1971
Ovis aries, Homo sapiens, Rattus norvegicus, Sus scrofa
Srivenugopal, K.S.; Ali-Osman, F.
Activity and distribution of the cysteine prodrug activating enzyme, 5-oxo-L-prolinase, in human normal and tumor tissues
Cancer Lett.
117
105-111
1997
Homo sapiens
Chen, X.; Schecter, R.L.; Griffith, O.W.; Hayward, M.A.; Alpert, L.C.; Batist, G.
Characterization of 5-oxo-L-prolinase in normal and tumor tissues of humans and rats: A potential new target for biochemical modulation of glutathione
Clin. Cancer Res.
4
131-138
1998
Homo sapiens, Rattus norvegicus
Chen, X.; Batist, G.
Sensitization effect of L-2-oxothiazolidine-4-carboxylate on tumor cells to melphalan and the role of 5-oxo-L-prolinase in glutathione modulation in tumor cells
Biochem. Pharmacol.
56
743-749
1998
Homo sapiens
Ruijter, G.J.; Mourad-Baars, P.E.; Ristoff, E.; Onkenhout, W.; Poorthuis, B.J.
Persistent 5-oxoprolinuria with normal glutathione synthase and 5-oxoprolinase activities
J. Inherit. Metab. Dis.
29
587
2006
Homo sapiens
Kumar, A.; Bachhawat, A.K.
A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis?
J. Biosci.
35
21-25
2010
Homo sapiens
Almaghlouth, I.; Mohamed, J.; Al-Amoudi, M.; Al-Ahaidib, L.; Al-Odaib, A.; Alkuraya, F.
5-Oxoprolinase deficiency: report of the first human OPLAH mutation
Clin. Genet.
82
193-196
2012
Homo sapiens (O14841), Homo sapiens
Calpena, E.; Deshpande, A.A.; Yap, S.; Kumar, A.; Manning, N.J.; Bachhawat, A.K.; Espinos, C.
New insights into the genetics of 5-oxoprolinase deficiency and further evidence that it is a benign biochemical condition
Eur. J. Pediatr.
174
407-411
2015
Homo sapiens (O14841), Homo sapiens
