Reference on EC 3.4.99.B1 - RCE1
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hollander, I.; Frommer, E.; Mallon, R.
Human Ras-Converting Enzyme (hRCE1) Endoproteolytic Activity on K-Ras-Derived Peptides
Anal. Biochem.
286
129-137
2000
Homo sapiens
Dolence, J.M.; Steward, L.E.; Dolence, E.K.; Wong, D.H.; Poulter, C.D.
Studies with Recombinant Saccharomyces cerevisiae CaaX Prenyl Protease Rce1p
Biochemistry
39
4096-4104
2000
Saccharomyces cerevisiae
Otto, J.C.; Kim, E.; Young, S.G.; Casey, P.J.
Cloning and characterization of a mammalian prenyl protein-specific protease
J. Biol. Chem.
274
8379-8382
1999
Homo sapiens (Q9Y256), Homo sapiens
Ashby, M.N.; Rine, J.
Ras and a-factor converting enzyme
Methods Enzymol.
250
235-251
1995
Saccharomyces cerevisiae
Trueblood, C.E.; Boyartchuk, V.L.; Picologlou, E.A.; Rozema, D.; Poulter, C.D.; Rine, J.
The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities
Mol. Cell. Biol.
20
4381-4392
2000
Saccharomyces cerevisiae
Boyartchuk.V.L.; Ashby, M.N.; Rine, J.
Modulation of Ras and a-factor function by carboxyl-terminal proteolysis
Science
275
1796-1800
1997
Saccharomyces cerevisiae
Pei, J.; Grishin, N.V.
Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases
Trends Biochem. Sci.
26
275-277
2001
Saccharomyces cerevisiae
Bergo, M.O.; Young, S.G.
Mammalian farnesylated protein-converting enzyme 1
Handbook of Proteolytic Enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , eds. )Academic Press
1
466-468
2004
Saccharomyces cerevisiae
-
Casey, P.J.; Rando, R.R.
Isoprenylated protein peptidase Rce1
Handbook of Proteolytic Enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , eds. )Academic Press
2
2123-2127
2004
Bos taurus, Saccharomyces cerevisiae, Homo sapiens, Mus musculus
-
Fueller, F.; Bergo, M.O.; Young, S.G.; Aktories, K.; Schmidt, G.
Endoproteolytic processing of RhoA by Rce1 is required for the cleavage of RhoA by Yersinia enterocolitica outer protein T
Infect. Immun.
74
1712-1717
2006
Homo sapiens
Bergo, M.O.; Lieu, H.D.; Gavino, B.J.; Ambroziak, P.; Otto, J.C.; Casey, P.J.; Walker, Q.M.; Young, S.G.
On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy
J. Biol. Chem.
279
4729-4736
2004
Mus musculus
Plummer, L.J.; Hildebrandt, E.R.; Porter, S.B.; Rogers, V.A.; McCracken, J.; Schmidt, W.K.
Mutational analysis of the ras converting enzyme reveals a requirement for glutamate and histidine residues
J. Biol. Chem.
281
4596-4605
2006
Arabidopsis thaliana, Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Schizosaccharomyces pombe
Michaelson, D.; Ali, W.; Chiu, V.K.; Bergo, M.; Silletti, J.; Wright, L.; Young, S.G.; Philips, M.
Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases
Mol. Biol. Cell
16
1606-1616
2005
Mus musculus
Porter, S.B.; Hildebrandt, E.R.; Breevoort, S.R.; Mokry, D.Z.; Dore, T.M.; Schmidt, W.K.
Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones
Biochim. Biophys. Acta
1773
853-862
2007
Arabidopsis thaliana, Saccharomyces cerevisiae, Homo sapiens
Wahlstrom, A.M.; Cutts, B.A.; Karlsson, C.; Andersson, K.M.; Liu, M.; Sjogren, A.K.; Swolin, B.; Young, S.G.; Bergo, M.O.
Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease
Blood
109
763-768
2007
Mus musculus
Gillespie, J.R.; Yokoyama, K.; Lu, K.; Eastman, R.T.; Bollinger, J.G.; Van Voorhis, W.C.; Gelb, M.H.; Buckner, F.S.
C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins
Mol. Biochem. Parasitol.
153
115-124
2007
Leishmania major, Trypanosoma brucei
Hollander, I.J.; Frommer, E.; Aulabaugh, A.; Mallon, R.
Human Ras converting enzyme endoproteolytic specificity at the P2' and P3' positions of K-Ras-derived peptides
Biochim. Biophys. Acta
1649
24-29
2003
Homo sapiens
Kyro, K.; Manandhar, S.P.; Mullen, D.; Schmidt, W.K.; Distefano, M.D.
Photoaffinity labeling of Ras converting enzyme 1 (Rce1p) using a benzophenone-containing peptide substrate
Bioorg. Med. Chem.
18
5675-5684
2010
Saccharomyces cerevisiae
Burrows, J.F.; Kelvin, A.A.; McFarlane, C.; Burden, R.E.; McGrattan, M.J.; De la Vega, M.; Govender, U.; Quinn, D.J.; Dib, K.; Gadina, M.; Scott, C.J.; Johnston, J.A.
USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity
J. Biol. Chem.
284
9587-9595
2009
Homo sapiens
Pei, J.; Mitchell, D.; Dixon, J.; Grishin, N.
Expansion of type II CAAX proteases reveals evolutionary origin of gamma-secretase subunit APH-1
J. Mol. Biol.
410
18-26
2011
Saccharomyces cerevisiae (Q03530)
Meissner, D.; Odman-Naresh, J.; Vogelpohl, I.; Merzendorfer, H.
A novel role of the yeast CaaX protease Ste24 in chitin synthesis
Mol. Biol. Cell
21
2425-2433
2010
Saccharomyces cerevisiae (Q03530), Saccharomyces cerevisiae BY4741 (Q03530)
Christiansen, J.R.; Kolandaivelu, S.; Bergo, M.O.; Ramamurthy, V.
RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments
Proc. Natl. Acad. Sci. USA
108
8862-8866
2011
Mus musculus (P57791)
Mohammed, I.; Hampton, S.E.; Ashall, L.; Hildebrandt, E.R.; Kutlik, R.A.; Manandhar, S.P.; Floyd, B.J.; Smith, H.E.; Dozier, J.K.; Distefano, M.D.; Schmidt, W.K.; Dore, T.M.
8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells
Bioorg. Med. Chem.
24
160-178
2016
Homo sapiens (Q9Y256), Homo sapiens
Gentry, L.R.; Nishimura, A.; Cox, A.D.; Martin, T.D.; Tsygankov, D.; Nishida, M.; Elston, T.C.; Der, C.J.
Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases
J. Biol. Chem.
290
22851-61
2015
Mus musculus (P57791)
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