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Information on EC 3.4.24.B35 - Vipera ammodytes ammodytes metalloproteinase VaH4

for references in articles please use BRENDA:EC3.4.24.B35
preliminary BRENDA-supplied EC number
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The expected taxonomic range for this enzyme is: Vipera ammodytes ammodytes
Reaction Schemes
Cleavage of Glu422-/-Leu423 and Glu520-/-Phe521 bond of alpha-chain of human fibrinogen. Fibrinogen beta-chain is hydrolysed only partially at Lys22-/-Arg23 and Pro28-Leu29. In insulin B-chain the enzyme preferentially cleaves Tyr16-/-Leu17, followed by Gln4-/-His5 and His10-/-Leu11
Synonyms
hemorrhagin vah4, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
Cleavage of Glu422-/-Leu423 and Glu520-/-Phe521 bond of alpha-chain of human fibrinogen. Fibrinogen beta-chain is hydrolysed only partially at Lys22-/-Arg23 and Pro28-Leu29. In insulin B-chain the enzyme preferentially cleaves Tyr16-/-Leu17, followed by Gln4-/-His5 and His10-/-Leu11
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