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Disease on EC 3.4.24.68 - tentoxilysin

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenoma, Islet Cell
Expression of receptors for tetanus toxin and monoclonal antibody A2B5 by pancreatic islet cells.
Anthrax
Antibody microarrays for native toxin detection.
Application of NMR methods to identify detection reagents for use in development of robust nanosensors.
Cytotoxic effects of a chimeric protein consisting of tetanus toxin light chain and anthrax toxin lethal factor in non-neuronal cells.
Inhibition of bacterial carbonic anhydrases and zinc proteases: from orphan targets to innovative new antibiotic drugs.
Mosquito inoculation: an alternative bioassay for toxins.
Mucosal delivery of antigens using adsorption to bacterial spores.
Pluronic F127-based systemic vaccine delivery systems.
Self-assembled peptide monolayers as a toxin sensing mechanism within arrayed microchannels.
THE IMMUNIZING POWER OF NUCLEOHISTON AND OF HISTON.
Using common spatial distributions of atoms to relate functionally divergent influenza virus n10 and n11 protein structures to functionally characterized neuraminidase structures, toxin cell entry domains, and non-influenza virus cell entry domains.
Apnea
Intensive Care Management of Severe Tetanus.
Arthritis, Rheumatoid
Dual antigenic recognition by cloned human gamma delta T cells.
Asthma
TH1/TH2 cytokine balance in patients with both type 1 diabetes mellitus and asthma.
Blepharospasm
The effects of tetanus toxin on the orbicularis oculi muscle.
Botulism
Bacterial Toxins, Current Perspectives.
Bioinformatic discovery of a toxin family in Chryseobacterium piperi with sequence similarity to botulinum neurotoxins.
BotR/A and TetR are alternative RNA polymerase sigma factors controlling the expression of the neurotoxin and associated protein genes in Clostridium botulinum type A and Clostridium tetani.
Botulinum and Tetanus Neurotoxins.
Botulinum neurotoxin E-insensitive mutants of SNAP-25 fail to bind VAMP but support exocytosis.
Cell entry strategy of clostridial neurotoxins.
Clostridial neurotoxin light chains: devices for SNARE cleavage mediated blockade of neurotransmission.
Clostridial Neurotoxins: Mechanism of SNARE Cleavage and Outlook on Potential Substrate Specificity Reengineering.
Clostridial Neurotoxins: Mode of Substrate Recognition and Novel Therapy Development.
Entry of a recombinant, full-length, atoxic tetanus neurotoxin into Neuro-2a cells.
Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons.
Insights into the different catalytic activities of Clostridium neurotoxins.
Insights into the Mechanisms by Which Clostridial Neurotoxins Discriminate between Gangliosides.
Pentavalent replicon vaccines against botulinum neurotoxins and tetanus toxin using DNA-based Semliki Forest virus replicon vectors.
Unique ganglioside recognition strategies for clostridial neurotoxins.
[Molecular mechanism of action of tetanus toxin and botulinum neurotoxins]
Bradycardia
Bradycardia of central origin produced by injections of tetanus toxin into the vagus nerve.
Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: Bradyarrhythmias, tachycardias, and prolonged interictal QT interval.
Cardiovascular effects of tetanus toxin after systemic and intraventricular administration in rats.
Brain Ischemia
Neuroprotective efficiency of tetanus toxin C fragment in model of global cerebral ischemia in Mongolian gerbils.
Breast Neoplasms
A plant-expressed conjugate vaccine breaks CD4(+) tolerance and induces potent immunity against metastatic Her2(+) breast cancer.
Brucellosis
[Effective simultaneous immunization with living brucellosis vaccine and with tetanus toxin.]
Carcinoma
Bacterial toxin's DNA vaccine serves as a strategy for the treatment of cancer, infectious and autoimmune diseases.
Binding and transcytosis of botulinum neurotoxin by polarized human colon carcinoma cells.
Carcinoma, Hepatocellular
Combination therapy of hepatocellular carcinoma by DNA shuffling-based VEGF vaccine and doxorubicin.
Cholera
A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice.
A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins.
A study of the mechanism of internalisation of tetanus toxin by primary mouse spinal cord cultures.
Activation of phospholipases A2 and D of a human neuroblastoma cell line (LA-N-2) by N-dodecyl-L-lysine amide (compound 24), a putative G protein activator: characteristics of inhibition by (-)-nicotine.
Analysis and isolation of embryonic mammalian neurons by fluorescence-activated cell sorting.
Antibody microarrays for native toxin detection.
Cell surface changes accompanying the neural differentiation of an embryonal carcinoma cell line.
Concanavalin A inhibits nicotinic acetylcholine receptor function in cultured chick ciliary ganglion neurons.
Delineation and comparison of ganglioside-binding epitopes for the toxins of Vibrio cholerae, Escherichia coli, and Clostridium tetani: evidence for overlapping epitopes.
Detection of bacterial toxins with monosaccharide arrays.
Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
Gangliosides of cultured astroglia.
Gangliosides, the thyrotropin receptor, and autoimmune thyroid disease.
Histological identification of premotor neurons for horizontal saccades in monkey and man by parvalbumin immunostaining.
Mapping the glycation sites in the neoglycoconjugate from hexasaccharide antigen of Vibrio cholerae, serotype Ogawa and the recombinant tetanus toxin C-fragment carrier.
Micrometer-sized supported lipid bilayer arrays for bacterial toxin binding studies through total internal reflection fluorescence microscopy.
Neuronal and glial cells in the superficial layers of early postnatal mouse neocortex: immunofluorescence observations.
Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses.
Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes.
Retrograde axonal and transsynaptic transport of macromolecules: physiological and pathophysiological importance.
Retrograde axonal transport of specific macromolecules as a tool for characterizing nerve terminal membranes.
Role of gangliosides in the uptake and retrograde axonal transport of cholera and tetanus toxin as compared to nerve growth factor and wheat germ agglutinin.
Role of membrane gangliosides in the binding and action of bacterial toxins.
Stepwise iodination. A general procedure for detoxification of proteins suitable for vaccine development and antiserum production.
The hydrophobicities of cholera toxin, tetanus toxin and their components.
[Recent advances in the molecular mechanism of action of bacterial toxins, in particular of diphtheria, cholera, coli, botulinum and shigella toxins as well as tetanospasmin and the toxins of staphylococcus aureus]
Chorea
Intracerebral injections of kainic acid and tetanus toxin: possible models for the signs of chorea and dystonia.
Communicable Diseases
An alternative treatment approach in tetanus: Botulinum toxin.
Characterization of neutralizing monoclonal antibodies directed against tetanus toxin fragment C.
Design and construction of immune phage antibody library against Tetanus neurotoxin: Production of single chain antibody fragments.
Expression and Purification of Tetanus Toxin Fragment C in Escherichia coli BL21(DE3).
Identification of a novel linear epitope in tetanus toxin recognized by a protective monoclonal antibody: Implications for vaccine design.
Contracture
A Study of Muscle in Contracture: The Permanent Shortening of Muscles caused by Tenotomy and Tetanus Toxin.
Decrease of muscle extensibility and reduction of sarcomere number in soleus muscle following a local injection of tetanus toxin.
Deglutition Disorders
Intensive Care Management of Severe Tetanus.
Diphtheria
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex.
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens.
A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons.
Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.
Adoptive immunotherapy in canine chimeras.
An observational study of antibody responses to a primary or subsequent pertussis booster vaccination in Australian healthcare workers.
An olfactory circuit increases the fidelity of visual behavior.
Antibody microarrays for native toxin detection.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Avian eyelid assay, a new diagnostic method for detecting botulinum neurotoxin serotypes A, B and E.
Cellular identification of water gustatory receptor neurons and their central projection pattern in Drosophila.
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.
Characterization of production processes for tetanus and diphtheria anatoxins.
Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age.
Concomitant administration of diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) with pentavalent rotavirus vaccine in Japanese infants.
Detoxification of diphtheria and tetanus toxin with formaldehyde. Detection of protein conjugates.
Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus.
Development of a guinea-pig model for potency/immunogenicity evaluation of diphtheria, tetanus acellular pertussis (DTaP) and Haemophilus influenzae type b polysaccharide conjugate vaccines.
Differential potencies of effector genes in adult Drosophila.
Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.
Ensilicated tetanus antigen retains immunogenicity: in vivo study and time-resolved SAXS characterization.
Expression and purification of a trivalent pertussis toxin-diphtheria toxin-tetanus toxin fusion protein in Escherichia coli.
Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain.
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.
Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens.
Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
Humoral and cell mediated immune responses to a pertussis containing vaccine in pregnant and nonpregnant women.
Hybrid tetanus toxin C fragment-diphtheria toxin translocation domain allows specific gene transfer into PC12 cells.
Immunodeficiency in alpha-mannosidosis: a matched case-control study on immunoglobulins, complement factors, receptor density, phagocytosis and intracellular killing in leucocytes.
Immunogenicity and reactogenicity of a single dose of a diphtheria--tetanus--acellular pertussis component vaccine (DTaP) compared to a diphtheria--tetanus toxoid (Td) and a diphtheria toxoid vaccine (d) in adults.
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
Lipid interaction of Pseudomonas aeruginosa exotoxin A. Acid-triggered permeabilization and aggregation of lipid vesicles.
Low pH induces a hydrophobic domain in the tetanus toxin molecule.
Measuring immunoglobulin g antibodies to tetanus toxin, diphtheria toxin, and pertussis toxin with single-antigen enzyme-linked immunosorbent assays and a bead-based multiplex assay.
Mosquito inoculation: an alternative bioassay for toxins.
Multi-epitope insert modulates solubility-based and chromatographic purification of human papilloma virus 16 L1-based vaccine without inhibiting virus-like particle assembly.
Multiplexed measurement of serum antibodies using an array biosensor.
Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach.
Pediatric diphtheria and tetanus toxoids-adsorbed vaccine: immune response to the first booster following the diphtheria and tetanus toxoids vaccine primary series.
Pneumococcal conjugate vaccine followed by pneumococcal polysaccharide vaccine; immunogenicity in patients with ataxia-telangiectasia.
Pre-clinical efficacy and characterization of candidate vaccines for treatment of opioid use disorders using clinically viable carrier proteins.
Serological evaluation of a simplified immunization schedule using quadruple DPT-polio vaccine in Burkina Faso.
Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis.
Simultaneous multicolor detection system of the single-molecular microbial antigen with total internal reflection fluorescence microscopy.
Specific peptides of casein pancreatic digestion enhance the production of tetanus toxin.
Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis.
Tetanus toxin induces fusion and aggregation of lipid vesicles containing phosphatidylinositol at low pH.
THE ELECTRICAL CHARGE OF TOXIN AND ANTITOXIN.
THE IMMUNIZING POWER OF NUCLEOHISTON AND OF HISTON.
The recombinant protein combined vaccine based on the fragment C of tetanus toxin and the cross-reacting material 197.
TOXIN-ANTITOXIN REACTION WITHOUT NEUTRALIZATION.
Use of in vitro Vero cell assay and ELISA in the United States potency test of vaccines containing adsorbed diphtheria and tetanus toxoids.
[A method for determining absorption of antigens or toxins through the skin; general intoxication and death of animals from percutaneous application of diphtheria or tetanus toxin.]
[Antibodies against vaccine-preventable diseases in pregnant women and their offspring. Diphtheria, pertussis, tetanus]
[ATTEMPT AT DEMONSTRATION OF DISULFIDE BONDS IN TETANUS TOXIN AND DIPHTHERIA TOXIN.]
[Effect of diphtheria and tetanus toxin on various types of cells cultured in vitro.]
[Effects of diphtheria and tetanus toxins on liver regeneration in the rat]
[Recent advances in the molecular mechanism of action of bacterial toxins, in particular of diphtheria, cholera, coli, botulinum and shigella toxins as well as tetanospasmin and the toxins of staphylococcus aureus]
[Use of monoclonal antibodies against horse immunoglobulin in an enzyme immunoassay of bacterial toxins and anatoxins]
Dyskinesias
Effect of the C-terminal domain of the heavy chain of tetanus toxin on dyskinesia caused by levodopa in 6-hydroxydopamine-lesioned rats.
Dystonia
Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B.
Intracerebral injections of kainic acid and tetanus toxin: possible models for the signs of chorea and dystonia.
The Regions on the Light Chain of Botulinum Neurotoxin Type A Recognized by T Cells from Toxin-Treated Cervical Dystonia Patients. The Complete Human T-Cell Recognition Map of the Toxin Molecule.
Epilepsies, Partial
A chronic focal epilepsy with mossy fiber sprouting follows recurrent seizures induced by intrahippocampal tetanus toxin injection in infant rats.
Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks.
Animal models of the epilepsies.
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.
Chronic Epileptic Foci in Neocortex: In Vivo and In Vitro Effects of Tetanus Toxin.
Chronic focal epilepsy induced by intracerebral tetanus toxin.
Chronic focal epilepsy induced by microinjection of tetanus toxin into the cat motor cortex.
Effects of tetanus toxin on functional inhibition after injection in separate cortical areas in rat.
Estimating coupling direction between neuronal populations with permutation conditional mutual information.
Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy.
Temporal profile of connexin 43 mRNA expression in a tetanus toxin-induced seizure disorder.
Tetanus neurotoxin-induced epilepsy in mouse visual cortex.
Zif268 and Fos-like immunoreactivity in tetanus toxin-induced epilepsy: reciprocal changes in the epileptic focus and the surround.
Epilepsy
'Dormant' inhibitory neurons: do they exist and what is their functional impact?
9-16 Hz oscillation precedes secondary generalization of seizures in the rat tetanus toxin model of epilepsy.
A characterization of epileptogenesis presented in hippocampal neural activity in a rat tetanus toxin model.
A machine learning approach to characterizing the effect of asynchronous distributed electrical stimulation on hippocampal neural dynamics in vivo.
Altered dentate filtering during the transition to seizure in the rat tetanus toxin model of epilepsy.
Altered expression of the voltage-gated calcium channel subunit ?2?-1: A comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.
Antiepileptic and antiamnesic effect of carbamazepine in experimental limbic epilepsy.
Antiepileptic effect of gap-junction blockers in a rat model of refractory focal cortical epilepsy.
Asynchronous Distributed Multielectrode Microstimulation Reduces Seizures in the Dorsal Tetanus Toxin Model of Temporal Lobe Epilepsy.
Bayesian Optimization of Asynchronous Distributed Microelectrode Theta Stimulation and Spatial Memory.
Brain hypometabolism in a model of chronic focal epilepsy in rat neocortex.
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.
Chronic epileptic foci in vitro in hippocampal slices from rats with the tetanus toxin epileptic syndrome.
Chronic focal epilepsy induced by microinjection of tetanus toxin into the cat motor cortex.
Chronic/semichronic limbic epilepsy produced by microinjection of tetanus toxin in cat hippocampus.
Dendritic shrinkage and dye-coupling between rat hippocampal CA1 pyramidal cells in the tetanus toxin model of epilepsy.
Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy.
Developmental neuroplasticity: roles in early life seizures and chronic epilepsy.
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in the rat.
Dynamical properties of LFPs from mice with unilateral injection of TeNT.
Effect of experimental limbic epilepsy on the estrus cycle and reproductive success in rats.
Ex vivo release of GABA from tetanus toxin-induced chronic epileptic foci decreased during the active seizure phase.
Expression of mRNAs encoding flip isoforms of GluR1 and GluR2 glutamate receptors is increased in rat hippocampus in epilepsy induced by tetanus toxin.
Forebrain ischaemia with CA1 cell loss impairs epileptogenesis in the tetanus toxin limbic seizure model.
Injectable phenytoin loaded polymeric microspheres for the control of temporal lobe epilepsy in rats.
Insights into the tetanus toxin model of early-onset epilepsy from long-term video monitoring during anticonvulsant therapy.
Investigation of the neuronal aggregate generating seizures in the rat tetanus toxin model of epilepsy.
Levetiracetam-loaded biodegradable polymer implants in the tetanus toxin model of temporal lobe epilepsy in rats.
Limbic epilepsy induced by tetanus toxin: a longitudinal electroencephalographic study.
Locally applied valproate enhances survival in rats after neocortical treatment with tetanus toxin and cobalt chloride.
Long-term seizure dynamics are determined by the nature of seizures and the mutual interactions between them.
Mesial temporal lobe epilepsy: pathogenesis, induced rodent models and lesions.
Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy.
Quantifying epileptogenesis in rats with spontaneous and responsive brain state dynamics.
Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy.
Seizure entrainment with polarizing low-frequency electric fields in a chronic animal epilepsy model.
Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.
Spontaneous and evoked high-frequency oscillations in the tetanus toxin model of epilepsy.
Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy.
Sustained and selective block of IPSPs in brain slices from rats made epileptic by intrahippocampal tetanus toxin.
Tetanus toxin and experimental epilepsy in rats.
Tetanus toxin as a tool for studying epilepsy.
The effect of experimental epilepsy induced by injection of tetanus toxin into the amygdala of the rat on eating behaviour and response to novelty.
The effects of tetanus toxin-induced limbic epilepsy on the exploratory response to novelty in the rat.
The Peptide Network between Tetanus Toxin and Human Proteins Associated with Epilepsy.
The tetanus toxin model of chronic epilepsy.
The thalamocortical circuit and the generation of epileptic spikes in rat models of focal epilepsy.
Time evolution of interhemispheric coupling in a model of focal neocortical epilepsy in mice.
[Anticonvulsive effect of stimulation of the mesencephalic reticular formation in animals with experimental photogenic epilepsy]
[Effect of diazepam on the epileptic activity of rats with experimental photogenic epilepsy]
[Photogenic epilepsy with localization of the generator of excitation in the lateral geniculate body (the phenomenon of a determining dispatch station)]
Epilepsy, Complex Partial
A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy.
Epilepsy, Temporal Lobe
A machine learning approach to characterizing the effect of asynchronous distributed electrical stimulation on hippocampal neural dynamics in vivo.
Altered expression of the voltage-gated calcium channel subunit ?2?-1: A comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.
Asynchronous Distributed Multielectrode Microstimulation Reduces Seizures in the Dorsal Tetanus Toxin Model of Temporal Lobe Epilepsy.
Bayesian Optimization of Asynchronous Distributed Microelectrode Theta Stimulation and Spatial Memory.
Dendritic shrinkage and dye-coupling between rat hippocampal CA1 pyramidal cells in the tetanus toxin model of epilepsy.
Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy.
Injectable phenytoin loaded polymeric microspheres for the control of temporal lobe epilepsy in rats.
Levetiracetam-loaded biodegradable polymer implants in the tetanus toxin model of temporal lobe epilepsy in rats.
Long-term seizure dynamics are determined by the nature of seizures and the mutual interactions between them.
Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy.
Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy.
Epileptic Syndromes
Chronic epileptic foci in vitro in hippocampal slices from rats with the tetanus toxin epileptic syndrome.
Chronic focal epilepsy induced by intracerebral tetanus toxin.
Development of chronic secondary epileptic foci following intrahippocampal injection of tetanus toxin in the rat.
Increased expression of GAD mRNA during the chronic epileptic syndrome due to intrahippocampal tetanus toxin.
Increased susceptibility to tetanus toxin-induced seizures in immature rats.
Injection of tetanus toxin into the neocortex elicits persistent epileptiform activity but only transient impairment of GABA release.
Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats.
Long-term changes in hippocampal physiology and learning ability of rats after intrahippocampal tetanus toxin.
Loss of hilar somatostatin neurons following tetanus toxin-induced seizures.
Neuropathology of the chronic epileptic syndrome induced by intrahippocampal tetanus toxin in rat: preservation of pyramidal cells and incidence of dark cells.
Sustained and selective block of IPSPs in brain slices from rats made epileptic by intrahippocampal tetanus toxin.
[Pathogenetic factors in experimental photogenic epilepsy]
Essential Tremor
Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor.
Fasciculation
Involvement of the nerve growth factor-inducible large external glycoprotein (NILE) in neurite fasciculation in primary cultures of rat brain.
Gastroenteritis
Safety and immunogenicity of a parenterally administered rotavirus VP8 subunit vaccine in healthy adults.
Glioma
Action of tetanus toxin on cholinergic neuroblastoma X glioma hybrid cells: selective blockade of Ca spikes.
L- and T-type calcium channels in cultured neuronal cell lines are insensitive to tetanus toxin.
Tetanus toxin attenuates the ability of phorbol myristate acetate to mobilize cytosolic protein kinase C in NG-108 cells.
Tetanus toxin binds with high affinity to neuroblastoma x glioma hybrid cells NG 108-15 and impairs their stimulated acetylcholine release.
Tetanus toxin inhibits neurotensin-induced mobilization of cytosolic protein kinase C activity in NG-108 cells.
Granulomatous Disease, Chronic
Processing and presentation of tetanus toxin by antigen-presenting cells from patients with chronic granulomatous disease (CGD) to human specific T cell clones are not impaired.
Hemifacial Spasm
The effects of tetanus toxin on the orbicularis oculi muscle.
Hepatitis B
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Establishment of hybridomas secreting human monoclonal antibodies against tetanus toxin and hepatitis B virus surface antigen.
Immunization with a peptide corresponding to chlamydial heat shock protein 60 increases the humoral immune response in C3H mice to a peptide representing variable domain 4 of the major outer membrane protein of Chlamydia trachomatis.
Mechanisms of Antigen Adsorption Onto an Aluminum-Hydroxide Adjuvant Evaluated by High-Throughput Screening.
Multiplexed measurement of serum antibodies using an array biosensor.
Hepatitis C
Immune response to fused core protein of hepatitis C virus and truncated tetanus toxin peptides in mice.
Hepatitis E
Using common spatial distributions of atoms to relate functionally divergent influenza virus n10 and n11 protein structures to functionally characterized neuraminidase structures, toxin cell entry domains, and non-influenza virus cell entry domains.
Herpes Simplex
A Salmonella typhimurium htrA live vaccine expressing multiple copies of a peptide comprising amino acids 8-23 of herpes simplex virus glycoprotein D as a genetic fusion to tetanus toxin fragment C protects mice from herpes simplex virus infection.
DNA vaccination against multiple myeloma.
Hypertension
Intensive Care Management of Severe Tetanus.
Infections
A transcutaneous vaccination system using a hydrogel patch for viral and bacterial infection.
Delivery of chemotherapeutic agents to the central nervous system.
Effect of cortisone and desoxycorticosterone on infection with tetanus spores and upon the toxicity of tetanus toxin.
Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration.
Human T cell leukemia/lymphoma virus type I infection of a CD4+ proliferative/cytotoxic T cell clone progresses in at least two distinct phases based on changes in function and phenotype of the infected cells.
Inhibition of the immune response to whooping cough and tetanus vaccines by malaria infection, and the effect of pertussis adjuvant.
Ketamine in the management of generalised cephalic tetanus.
More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines.
Protection against Staphylococcus aureus and tetanus infections by a combined vaccine containing SasA and TeNT?Hc in mice.
Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines.
Soluble N-ethylmaleimide-sensitive factor attachment protein receptors required during Trypanosoma cruzi parasitophorous vacuole development.
Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis.
Influenza, Human
A fully human IgG1 anti-PD-L1 MAb in an in vitro assay enhances antigen-specific T-cell responses.
Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides.
Does tetanus toxin have a sequence homology with the haemagglutinin of influenza virus?
Efficacy of intravenous immunoglobulin preparations against viral and bacterial infections in mouse protection tests.
Enrichment and detection of live antigen-specific CD4(+) and CD8(+) T cells based on cytokine secretion.
Expression of HLA-DP0401 molecules for identification of DP0401 restricted antigen specific T cells.
Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4+ memory T cells.
Maintenance of HIV-Specific Memory B-Cell Responses in Elite Controllers Despite Low Viral Burdens.
Manipulation of pathogen-derived genes to influence antigen presentation via DNA vaccines.
Reassessing the role of HLA-DRB3 T-cell responses: Evidence for significant expression and complementary antigen presentation.
The heat shock protein Hsp70 enhances antigen-specific proliferation of human CD4+ memory T cells.
The LTR72 mutant of heat-labile enterotoxin of Escherichia coli enhances the ability of peptide antigens to elicit CD4(+) T cells and secrete gamma interferon after coapplication onto bare skin.
Insulinoma
Ca(2+) influx and cAMP elevation overcame botulinum toxin A but not tetanus toxin inhibition of insulin exocytosis.
Laryngismus
Intensive Care Management of Severe Tetanus.
Lung Neoplasms
Tetanus toxin as a marker for small-cell lung cancer cell lines.
Lymphoma
An anti-CD19 antibody coupled to a tetanus toxin peptide induces efficient Fas ligand (FasL)-mediated cytotoxicity of a transformed human B cell line by specific CD4+ T cells.
DNA vaccines against lymphoma: promotion of anti-idiotypic antibody responses induced by single chain Fv genes by fusion to tetanus toxin fragment C.
DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma.
Escherichia coli-based production of a tumor idiotype antibody fragment - tetanus toxin fragment C fusion protein vaccine for B cell lymphoma.
Plant viral genes in DNA idiotypic vaccines activate linked CD4+ T-cell mediated immunity against B-cell malignancies.
Lymphoma, B-Cell
An anti-CD19 antibody coupled to a tetanus toxin peptide induces efficient Fas ligand (FasL)-mediated cytotoxicity of a transformed human B cell line by specific CD4+ T cells.
DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma.
Escherichia coli-based production of a tumor idiotype antibody fragment - tetanus toxin fragment C fusion protein vaccine for B cell lymphoma.
Peptide-antibody conjugates for tumour therapy: a MHC-class-II-restricted tetanus toxin peptide coupled to an anti-Ig light chain antibody can induce cytotoxic lysis of a human B-cell lymphoma by specific CD4 T cells.
Lymphoma, Non-Hodgkin
Application of NMR methods to identify detection reagents for use in development of robust nanosensors.
Malaria
Construction and immunogenicity in mice of attenuated Salmonella typhi expressing Plasmodium falciparum merozoite surface protein 1 (MSP-1) fused to tetanus toxin fragment C.
Genetic detoxification of an aroA Salmonella enterica serovar Typhimurium vaccine strain does not compromise protection against virulent Salmonella and enhances the immune responses towards a protective malarial antigen.
Lymphocyte response to tetanus toxin T-cell epitopes: effects of tetanus vaccination and concurrent malaria prophylaxis.
Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara.
Presentation of T-cell epitopes assembled as multiple-antigen peptides to murine and human T lymphocytes.
Stimulation of a memory B cell response does not require primed helper T cells.
Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination.
Measles
An efficacious recombinant subunit vaccine against the salmonid rickettsial pathogen Piscirickettsia salmonis.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Human T-lymphotropic virus type 1 peptides in chimeric and multivalent constructs with promiscuous T-cell epitopes enhance immunogenicity and overcome genetic restriction.
Limitations of in vivo IL-12 supplementation strategies to induce Th1 early life responses to model viral and bacterial vaccine antigens.
Promiscuous T cell epitopes boosts specific IgM immune response against a P0 peptide antigen from sea lice in different teleost species.
Recombinant vaccines against infectious hematopoietic necrosis virus: production by the Caulobacter crescentus S-layer protein secretion system and evaluation in laboratory trials.
Melanoma
Development and validation of an anion-exchange LC-UV method for the quantification and purity determination of the DNA plasmid pDERMATT.
Meningomyelocele
The action of tetanus toxin: a case report.
Motor Neuron Disease
Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease.
Movement Disorders
Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B.
Multiple Sclerosis
Instruments for oral disease-intervention strategies: recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis.
Mumps
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Muscle Rigidity
Intensive Care Management of Severe Tetanus.
Tetanus.
Tetanus: a review.
Muscle Spasticity
Attempt to curtail the observation period of mice in the tetanus vaccine potency tests.
Beta-amino-thiols inhibit the zinc metallopeptidase activity of tetanus toxin light chain.
Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.
Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
Clostridial Neurotoxins: Mode of Substrate Recognition and Novel Therapy Development.
EVIDENCE FOR CENTRAL ANTISPASTIC EFFECT OF BOTULINUM TOXIN TYPE A.
High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein.
Insights in metabolism and toxin production from the complete genome sequence of Clostridium tetani.
Insights into the different catalytic activities of Clostridium neurotoxins.
Molecular basis for tetanus toxin coreceptor interactions.
Multiple domains of tetanus toxin direct entry into primary neurons.
Neuronal sensitivity to tetanus toxin requires gangliosides.
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways.
Relation of spastic and flaccid paralysis to retrograde transport of 125I-tetanus toxin and its 125I-Ibc fragment. Modulating effect of F (ab) antibodies directed to specific areas on the toxin molecule.
Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.
Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons.
Tetanus and botulinum toxins block the release of acetylcholine from slices of rat striatum and from the isolated electric organ of Torpedo at different concentrations.
Tetanus toxin as a neurobiological tool to study mechanisms of neuronal cell death in the mammalian brain.
Tetanus Toxin Synthesis is Under the Control of A Complex Network of Regulatory Genes in Clostridium tetani.
The genome sequence of Clostridium tetani, the causative agent of tetanus disease.
The structure of the tetanus toxin reveals pH-mediated domain dynamics.
The use of antibody Fab fragments specifically directed to two different complementary parts of the tetanus toxin molecule for studying the mode of action of the toxin.
Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.
Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
[Mechanism of action and therapeutic uses of botulinum and tetanus neurotoxins]
[Molecular mechanism of action of tetanus toxin and botulinum neurotoxins]
[On certain characteristics of functional changes of the central nervous system in experimental tetanus and on the mechanisms of action of tetanus toxin. II. Role of spinal mechanisms in convulsions and in spastic syndrome in tetanus.]
Muscular Atrophy
Tetanus toxin preserves skeletal muscle contractile force and size during limb immobilization.
Muscular Atrophy, Spinal
Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy.
Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin.
Myocardial Ischemia
[Characteristics of the rhythmic activity of a normal and a damaged heart during hyperactivity of spinal cord preganglionic neurons]
Neoplasms
Antigen-presenting human T cells and antigen-presenting B cells induce a similar cytokine profile in specific T cell clones.
Application of NMR methods to identify detection reagents for use in development of robust nanosensors.
Bacterial toxin's DNA vaccine serves as a strategy for the treatment of cancer, infectious and autoimmune diseases.
Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen.
Delivery of chemotherapeutic agents to the central nervous system.
DNA fusion gene vaccines against cancer: from the laboratory to the clinic.
DNA fusion vaccine designed to induce cytotoxic T cell responses against defined peptide motifs: implications for cancer vaccines.
DNA vaccination against multiple myeloma.
DNA vaccines against cancer: from genes to therapy.
Escherichia coli-based production of a tumor idiotype antibody fragment - tetanus toxin fragment C fusion protein vaccine for B cell lymphoma.
Expression of receptors for tetanus toxin and monoclonal antibody A2B5 by pancreatic islet cells.
First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427).
Identification and assembly of V genes as idiotype-specific DNA fusion vaccines in multiple myeloma.
Inhibition of a vaccine-induced anti-tumor B cell response by soluble protein antigen in the absence of continuing T cell help.
New strategies for vaccination and imunomodulation in NHL.
Peptide-antibody conjugates for tumour therapy: a MHC-class-II-restricted tetanus toxin peptide coupled to an anti-Ig light chain antibody can induce cytotoxic lysis of a human B-cell lymphoma by specific CD4 T cells.
Recent Advances in Design of Immunogenic and Effective Naked DNA Vaccines against Cancer.
Recombinant fusion peptides containing single or multiple repeats of a ubiquitous T-helper epitope are highly immunogenic.
Retargeted clostridial neurotoxins as novel agents for treating chronic diseases.
scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor.
scFv6.C4 DNA vaccine with fragment C of tetanus toxin increases protective immunity against CEA-expressing tumor.
Tetanus toxin as a marker for small-cell lung cancer cell lines.
Tetanus toxin interactions with the thyroid: decreased toxin binding to membranes from a thyroid tumor with a thyrotropin receptor defect and in vivo stimulation of thyroid function.
Tumor necrosis factor alpha inhibits the suppressive effect of regulatory T cells on the hepatitis B virus-specific immune response.
Nervous System Diseases
Cephalic tetanus from penetrating orbital wound.
Neural Tube Defects
Acetylcholinesterase in neural tube defects: a model using chick embryo amniotic fluid.
Neuroblastoma
Action of tetanus toxin on cholinergic neuroblastoma X glioma hybrid cells: selective blockade of Ca spikes.
Characterization of the binding and internalization of tetanus toxin in a neuroblastoma hybrid cell line.
Detection of minimal disease in bone marrow of neuroblastoma patients by immunofluorescence.
Flow cytometric analysis of tetanus toxin binding to neuroblastoma cells.
Interaction of tetanus toxin and toxoid with cultured neuroblastoma cells. Analysis by immunofluorescence.
L- and T-type calcium channels in cultured neuronal cell lines are insensitive to tetanus toxin.
Removal of neuroblastoma cells from bone marrow by a direct monoclonal antibody rosetting technique.
Tetanus toxin attenuates the ability of phorbol myristate acetate to mobilize cytosolic protein kinase C in NG-108 cells.
Tetanus toxin binding to neuroblastoma cells differentiated by antimitotic agents.
Tetanus toxin binds with high affinity to neuroblastoma x glioma hybrid cells NG 108-15 and impairs their stimulated acetylcholine release.
Tetanus toxin blocks Ca spikes in neuroblastoma clone N1E-115 cells.
Tetanus toxin C fragment-conjugated nanoparticles for targeted drug delivery to neurons.
Tetanus toxin inhibits neurotensin-induced mobilization of cytosolic protein kinase C activity in NG-108 cells.
Tetanus toxin labeling as a novel rapid and highly specific tool in human neuroblastoma differential diagnosis.
Tetanus toxin: a rapid and selective blockade of the calcium, but not sodium, component of action potentials in cultured neuroblastoma N1E-115 cells.
The study of clostridial and related toxins. The search for unique mechanisms and common denominators.
Neurodegenerative Diseases
Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy.
Neuroprotective efficiency of tetanus toxin C fragment in model of global cerebral ischemia in Mongolian gerbils.
Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease.
Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin.
Neuromuscular Diseases
Tetanus: a diagnostic challenge in the Western world.
Paralysis
Antitoxin's effect on tetanus toxin induced sphincter pupillae paralysis in the rabbit.
Attempt to curtail the observation period of mice in the tetanus vaccine potency tests.
Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.
Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
Clostridial Neurotoxins: Mode of Substrate Recognition and Novel Therapy Development.
DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies.
EVIDENCE FOR CENTRAL ANTISPASTIC EFFECT OF BOTULINUM TOXIN TYPE A.
Fragment A-B of tetanus toxin does not block neuromuscular transmission in the goldfish.
High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein.
Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins.
Insights in metabolism and toxin production from the complete genome sequence of Clostridium tetani.
Insights into the different catalytic activities of Clostridium neurotoxins.
Molecular basis for tetanus toxin coreceptor interactions.
Multiple domains of tetanus toxin direct entry into primary neurons.
Neuronal sensitivity to tetanus toxin requires gangliosides.
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways.
Relation of spastic and flaccid paralysis to retrograde transport of 125I-tetanus toxin and its 125I-Ibc fragment. Modulating effect of F (ab) antibodies directed to specific areas on the toxin molecule.
Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.
SV2 mediates entry of tetanus neurotoxin into central neurons.
Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons.
Tetanus and botulinum toxins block the release of acetylcholine from slices of rat striatum and from the isolated electric organ of Torpedo at different concentrations.
Tetanus toxin as a neurobiological tool to study mechanisms of neuronal cell death in the mammalian brain.
Tetanus Toxin Synthesis is Under the Control of A Complex Network of Regulatory Genes in Clostridium tetani.
The effect of lanthanum on nerve terminals in goldfish muscle after paralysis with tetanus toxin.
The effect of the treatment of crude tetanus toxin with ganglioside cerebroside complex on sphincter paralysis in the rabbit's eye.
The genome sequence of Clostridium tetani, the causative agent of tetanus disease.
The interaction between aminoquinolines and presynaptically acting neurotoxins.
The structure of the tetanus toxin reveals pH-mediated domain dynamics.
The use of antibody Fab fragments specifically directed to two different complementary parts of the tetanus toxin molecule for studying the mode of action of the toxin.
Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.
Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
[Mechanism of action and therapeutic uses of botulinum and tetanus neurotoxins]
[Molecular mechanism of action of tetanus toxin and botulinum neurotoxins]
Parkinson Disease
Antidepressant effects of C-Terminal domain of the heavy chain of tetanus toxin in a rat model of depression.
Effectiveness of Fragment C Domain of Tetanus Toxin and Pramipexole in an Animal Model of Parkinson's Disease.
Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice.
The C-terminal domain of the heavy chain of tetanus toxin prevents the oxidative and nitrosative stress induced by acute toxicity of 1-methyl-4-phenylpyridinium, a rat model of Parkinson's disease.
Parkinsonian Disorders
[Formation of a generator of pathologically enhanced excitation in the caudate nucleus in experimental parkinsonism]
Perinatal Death
Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus.
Peripheral Nerve Injuries
BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury.
Pheochromocytoma
A role for cGMP during tetanus toxin blockade of acetylcholine release in the rat pheochromocytoma (PC12) cell line.
Comparison of the intracellular effects of clostridial neurotoxins on exocytosis from streptolysin O-permeabilized rat pheochromocytoma (PC 12) and bovine adrenal chromaffin cells.
Complex ganglioside expression and tetanus toxin binding by PC12 pheochromocytoma cells.
Introduction of macromolecules into bovine adrenal medullary chromaffin cells and rat pheochromocytoma cells (PC12) by permeabilization with streptolysin O: inhibitory effect of tetanus toxin on catecholamine secretion.
Periodate-modified gangliosides enhance surface binding of tetanus toxin to PC12 pheochromocytoma cells.
Studies on the intoxication pathway of tetanus toxin in the rat pheochromocytoma (PC12) cell line. Binding, internalization, and inhibition of acetylcholine release.
Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells.
Poliomyelitis
Axonal transport in neurological disease.
[Combined vitamin K with tetanus toxin in the treatment of poliomyelitis.]
Prion Diseases
Effective levels of tetanus toxin can be made in a production medium totally lacking both animal (e.g., brain heart infusion) and dairy proteins or digests (e.g., casein hydrolysates).
Therapeutic Assay with the Non-toxic C-Terminal Fragment of Tetanus Toxin (TTC) in Transgenic Murine Models of Prion Disease.
Prostatic Neoplasms
DNA Vaccination with Electroporation Induces Increased Antibody Responses in Patients with Prostate Cancer.
Rabies
A peptide-linked recombinant glucocerebrosidase for targeted neuronal delivery: Design, production, and assessment.
Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR.
Improved Lentiviral Transduction of ALS Motoneurons in vivo via Dual Targeting.
Respiratory Insufficiency
Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
Sarcoma, Avian
A Quantitative Comparison of the Effects of the Beta Rays of Radium on the Agent of the Rous Sarcoma, on the Bacteriophage, on Tetanus Toxin and on Certain Bacteria, Antibodies and Ferments.
Schistosomiasis
Sm14 of Schistosoma mansoni in fusion with tetanus toxin fragment C induces immunoprotection against tetanus and schistosomiasis in mice.
Seizures
9-16 Hz oscillation precedes secondary generalization of seizures in the rat tetanus toxin model of epilepsy.
A chronic focal epilepsy with mossy fiber sprouting follows recurrent seizures induced by intrahippocampal tetanus toxin injection in infant rats.
A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy.
A machine learning approach to characterizing the effect of asynchronous distributed electrical stimulation on hippocampal neural dynamics in vivo.
Aberrant Timm-stained fibres in the dentate gyrus following tetanus toxin-induced seizures in the rat.
Altered dentate filtering during the transition to seizure in the rat tetanus toxin model of epilepsy.
Altered expression of the voltage-gated calcium channel subunit ?2?-1: A comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.
Animal models of the epilepsies.
Antiepileptic effect of gap-junction blockers in a rat model of refractory focal cortical epilepsy.
Asynchronous Distributed Multielectrode Microstimulation Reduces Seizures in the Dorsal Tetanus Toxin Model of Temporal Lobe Epilepsy.
Bayesian Optimization of Asynchronous Distributed Microelectrode Theta Stimulation and Spatial Memory.
Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: Bradyarrhythmias, tachycardias, and prolonged interictal QT interval.
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.
Chronic focal epilepsy induced by intracerebral tetanus toxin.
Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy.
Developmental neuroplasticity: roles in early life seizures and chronic epilepsy.
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in the rat.
Effect of seizures on hippocampal peptidergic neurons.
Effect of tetanus toxin on basal and evoked release of 5-hydroxytryptamine and dopamine in rat hippocampus in vivo.
Epileptiform syndrome in rats produced by injecting tetanus toxin into the hippocampus.
Estimating coupling direction between neuronal populations with permutation conditional mutual information.
Forebrain ischaemia with CA1 cell loss impairs epileptogenesis in the tetanus toxin limbic seizure model.
Gliosis in the Mice Hippocampus Without Neuronal Death After Systemic Administration of High Dosage of Tetanus Toxin.
Increased susceptibility to tetanus toxin-induced seizures in immature rats.
Influence of intracerebroventricular administration of tetanus toxin on experimental seizures and protection afforded by some antiepileptic drugs in mice.
Insights into the tetanus toxin model of early-onset epilepsy from long-term video monitoring during anticonvulsant therapy.
Intrahippocampal tetanus toxin produces generalized convulsions and neurodegeneration in rats: antagonism by NMDA receptor blockers.
Investigation of the neuronal aggregate generating seizures in the rat tetanus toxin model of epilepsy.
Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats.
Levetiracetam-loaded biodegradable polymer implants in the tetanus toxin model of temporal lobe epilepsy in rats.
Local circuit abnormalities in chronically epileptic rats after intrahippocampal tetanus toxin injection in infancy.
Long-term seizure dynamics are determined by the nature of seizures and the mutual interactions between them.
Loss of hilar somatostatin neurons following tetanus toxin-induced seizures.
Neuronal activity and the establishment of normal and epileptic circuits during brain development.
Neuropathology of the chronic epileptic syndrome induced by intrahippocampal tetanus toxin in rat: preservation of pyramidal cells and incidence of dark cells.
Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy.
Physiological and behavioural consequences of seizures induced in the rat by intrahippocampal tetanus toxin.
Predicting the stimulation effectiveness using pre-stimulation neural states via optogenetic activation of the medial septum glutamatergic neurons modulating the hippocampal neural activity.
Prevention by the NMDA receptor antagonist, MK801 of neuronal loss produced by tetanus toxin in the rat hippocampus.
Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy.
Recurrent seizures and the molecular maturation of hippocampal and neocortical glutamatergic synapses.
Seizure entrainment with polarizing low-frequency electric fields in a chronic animal epilepsy model.
Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy.
Spine loss and other persistent alterations of hippocampal pyramidal cell dendrites in a model of early-onset epilepsy.
Spontaneous and evoked high-frequency oscillations in the tetanus toxin model of epilepsy.
Sustained and selective block of IPSPs in brain slices from rats made epileptic by intrahippocampal tetanus toxin.
Tetanus toxin as a neurobiological tool to study mechanisms of neuronal cell death in the mammalian brain.
Tetanus toxin induces long-term changes in excitation and inhibition in the rat hippocampal CA1 area.
Tetanus toxin-induced seizures cause microglial activation in rat hippocampus.
Tetanus toxin-induced seizures in infant rats and their effects on hippocampal excitability in adulthood.
[Convulsion threshold during tetanus toxin poisoning as the index of the functional state of the central nervous system.]
[Generalized tetanus with intractable autonomic cardiovascular instability in an aged woman]
[On certain characteristics of functional changes of the central nervous system in experimental tetanus and on the mechanisms of action of tetanus toxin. II. Role of spinal mechanisms in convulsions and in spastic syndrome in tetanus.]
[Photogenic epilepsy with localization of the generator of excitation in the lateral geniculate body (the phenomenon of a determining dispatch station)]
Severe Combined Immunodeficiency
Antigen recognition by MHC-incompatible cells of a human mismatched chimera.
Sleep Apnea Syndromes
Tetanospasmin injection treating sleep disordered breathing.
Spasm
Intensive Care Management of Severe Tetanus.
Pharmacological management of tetanus: an evidence-based review.
Tetanus--still a topic of present interest: a report of 27 cases from a Belgian referral hospital.
Tetanus.
Tetanus: a case report.
Tetanus: a diagnostic challenge in the Western world.
Tetanus: a review.
The effects of tetanus toxin on the orbicularis oculi muscle.
[Marked ST segment elevation in ECG during fiberscope-guided nasotracheal intubation in a patient with tetanus]
[Mechanism of paradoxical resistance of the digastric muscle to the action of tetanus toxin]
[Recent advances in the molecular mechanism of action of bacterial toxins, in particular of diphtheria, cholera, coli, botulinum and shigella toxins as well as tetanospasmin and the toxins of staphylococcus aureus]
Spinal Cord Injuries
Neuroprotective effects of C-terminal domain of tetanus toxin on rat brain against motorneuron damages after experimental spinal cord injury.
Therapeutic effects of Tetanus neurotoxin in spinal cord injury: a case series on four dogs.
Status Epilepticus
Altered expression of the voltage-gated calcium channel subunit ?2?-1: A comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.
Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy.
Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.
Stroke
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke.
Tachycardia
Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: Bradyarrhythmias, tachycardias, and prolonged interictal QT interval.
Intensive Care Management of Severe Tetanus.
Tetanus
"BINACLE" assay for in vitro detection of active tetanus neurotoxin in toxoids.
"Universal" T helper cell determinants enhance immunogenicity of a Plasmodium falciparum merozoite surface antigen peptide.
'Dormant' inhibitory neurons: do they exist and what is their functional impact?
10E8-like neutralizing antibodies against HIV-1 induced using a precisely designed conformational peptide as a vaccine prime.
125I-Labelled tetanus toxin as a neuronal marker in tissue cultures derived from embryonic CNS.
2.3 A crystal structure of tetanus neurotoxin light chain.
35 mM K(+)-stimulated 45Ca2+ uptake in cerebellar granule cell cultures mainly results from NMDA receptor activation.
9-16 Hz oscillation precedes secondary generalization of seizures in the rat tetanus toxin model of epilepsy.
A bacterial flagellin, Vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity.
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex.
A candidate carrier protein for beta-human chorionic gonadotropin: 54,000-molecular-weight fragment of tetanus toxin.
A cell-free system for Ca2+-regulated exocytosis.
A cell-free system for regulated exocytosis in PC12 cells.
A Central Amygdala-Globus Pallidus Circuit Conveys Unconditioned Stimulus-Related Information and Controls Fear Learning.
A central neural circuit for experience-independent olfactory and courtship behavior in Drosophila melanogaster.
A characterization of epileptogenesis presented in hippocampal neural activity in a rat tetanus toxin model.
A chimeric peptide of intestinal trefoil factor containing cholesteryl ester transfer protein B cell epitope significantly inhibits atherosclerosis in rabbits after oral administration.
A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice.
A chronic focal epilepsy with mossy fiber sprouting follows recurrent seizures induced by intrahippocampal tetanus toxin injection in infant rats.
A comparison of enzyme immunoassay and bioassay for the quantitative determination of antibodies to tetanus toxin.
A comparison of immunogenicity and in vivo distribution of Salmonella enterica serovar Typhi and Typhimurium live vector vaccines delivered by mucosal routes in the murine model.
A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy.
A conformational change of C-fragment of tetanus neurotoxin reduced its ganglioside binding activity but did not destroy its immunogenicity.
A correlation between the appearance and the evolution of tetanus toxin binding cells and neurogenesis.
A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation.
A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice.
A disulfide conjugate between anti-tetanus antibodies and HIV (37-72)Tat neutralizes tetanus toxin inside chromaffin cells.
A DNA fusion vaccine induces bactericidal antibodies to a peptide epitope from the PorA porin of Neisseria meningitidis.
A fast and robust method for automated analysis of axonal transport.
A few remarks on the preparation of tetanus toxin and toxoid on casein hydrolysate medium.
A fully human IgG1 anti-PD-L1 MAb in an in vitro assay enhances antigen-specific T-cell responses.
A genetic fusion construct between the tetanus toxin C fragment and the lysosomal acid hydrolase beta-glucuronidase expresses a bifunctional protein with enhanced secretion and neuronal uptake.
A genetic fusion GDNF-C fragment of tetanus toxin prolongs survival in a symptomatic mouse ALS model.
A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice.
A handheld platform for target protein detection and quantification using disposable nanopore strips.
A helper phage to improve single-chain antibody presentation in phage display.
A heterologous helper T cell epitope enhances the immunogenicity of a multiple antigenic peptide vaccine targeting the cryptic loop neutralizing determinant of Bacillus anthracis.
A Heterologous Reporter Defines the Role of the Tetanus Toxin Interchain Disulfide in Light-Chain Translocation.
A late phase of exocytosis from synaptosomes induced by elevated [Ca2+]i is not blocked by Clostridial neurotoxins.
A machine learning approach to characterizing the effect of asynchronous distributed electrical stimulation on hippocampal neural dynamics in vivo.
A means for targeting therapeutics to peripheral nervous system neurons with axonal damage.
A mechanism of the thearubigin fraction of black tea (Camellia sinensis) extract protecting against the effect of tetanus toxin.
A Method of producing Tetanus Toxin.
A microflocculation test for assay of tetanus toxin.
A mimotope gene encoding the major IgE epitope of allergen Phl p 5 for epitope-specific immunization.
A model system for the investigation of heterologous protein secretion pathways in Lactococcus lactis.
A Modification of the Hygienic Laboratory Method for the Production of Tetanus Toxin.
A modified Mueller medium without native protein for tetanus toxin production.
A monoclonal antibody directed against quail tyrosine hydroxylase: description and use in immunocytochemical studies on differentiating neural crest cells.
A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells.
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens.
A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins.
A neuroectoderm-associated ganglioside participates in fibronectin receptor-mediated adhesion of germinal cells to fibronectin.
A new neuronal marker identified by phosphorylcholine-binding myeloma proteins.
A new role for complement C3: regulation of antigen processing through an inhibitory activity.
A non-viral vector for targeting gene therapy to motoneurons in the CNS.
A nontoxic chimeric enterotoxin adjuvant induces protective immunity in both mucosal and systemic compartments with reduced IgE antibodies.
A novel and simple procedure for determining T cell epitopes in protein antigens.
A novel C3d-containing oligomeric vaccine provides insight into the viability of testing human C3d-based vaccines in mice.
A Novel High-Potency Tetanus Vaccine.
A novel multi-epitope peptide vaccine against cancer: An in silico approach.
A novel peptide defined through phage display for therapeutic protein and vector neuronal targeting.
A novel single-domain antibody multimer that potently neutralizes tetanus neurotoxin.
A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells.
A peptide carrier with a built-in vaccine adjuvant: construction of immunogenic conjugates.
A peptide-linked recombinant glucocerebrosidase for targeted neuronal delivery: Design, production, and assessment.
A pharmacological study of Renshaw cell inhibition.
A Pilot Study to Assess Safety and Feasibility of Intrathecal Immunoglobulin for the Treatment of Adults with Tetanus.
A plant-expressed conjugate vaccine breaks CD4(+) tolerance and induces potent immunity against metastatic Her2(+) breast cancer.
A possible explanation for the discrepancy between ELISA and neutralising antibodies to tetanus toxin.
A Precipitative Method for the Titration of Tetanus Toxin and Antitoxin.
A preclinical evaluation of aminopyridines as putative therapeutic agents in the treatment of botulism.
A probiotic treatment increases the immune response induced by the nasal delivery of spore-adsorbed TTFC.
A Quantitative Comparison of the Effects of the Beta Rays of Radium on the Agent of the Rous Sarcoma, on the Bacteriophage, on Tetanus Toxin and on Certain Bacteria, Antibodies and Ferments.
A radioimmunoassay for tetanus antibodies using protein A - containing Staphylococcus aureus.
A radioimmunoassay to monitor synaptic activity in hippocampal neurons in vitro.
A recombinant live attenuated strain of Vibrio cholerae induces immunity against tetanus toxin and Bordetella pertussis tracheal colonization factor.
A recombinant multi-epitope, multi-stage malaria vaccine candidate expressed in Escherichia coli.
A review of the molecular structure of tetanus toxin.
A role for cGMP during tetanus toxin blockade of acetylcholine release in the rat pheochromocytoma (PC12) cell line.
A role for SNAP-25 but not VAMPs in store-mediated Ca2+ entry in human platelets.
A role for synaptotagmin VII-regulated exocytosis of lysosomes in neurite outgrowth from primary sympathetic neurons.
A Salmonella typhimurium htrA live vaccine expressing multiple copies of a peptide comprising amino acids 8-23 of herpes simplex virus glycoprotein D as a genetic fusion to tetanus toxin fragment C protects mice from herpes simplex virus infection.
A semi-continuous method for the large-scale production of tetanus toxin.
A sensitive and rapid fluorescence-based assay for determination of tetanus toxin peptidase activity.
A simple method for obtaining highly potent tetanus toxin.
A simplified method for the preparation of tetanus toxin binding fragment for neurobiology.
A single dose of recombinant Salmonella typhimurium induces specific humoral immune responses against heterologous Eimeria tenella antigens in chicken.
A single human monoclonal antibody that confers total protection from tetanus.
A single mutation in the recombinant light chain of tetanus toxin abolishes its proteolytic activity and removes the toxicity seen after reconstitution with native heavy chain.
A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice.
A solid-phase enzyme immunoassay for the detection of tetanus toxin using human and murine monoclonal antibodies.
A somatic gene transfer approach using recombinant fusion proteins to map muscle-motoneuron projections in Xenopus spinal cord.
A stable interaction between syntaxin 1a and synaptobrevin 2 mediated by their transmembrane domains.
A Study of Muscle in Contracture: The Permanent Shortening of Muscles caused by Tenotomy and Tetanus Toxin.
A study of the action of tetanus toxin at rat soleus neuromuscular junctions.
A study of the immunity against tetanus toxin following the use of a combined typhoid-tetanus vaccine.
A study of the mechanism of internalisation of tetanus toxin by primary mouse spinal cord cultures.
A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons.
A tetanus toxin sensitive protein other than VAMP 2 is required for exocytosis in the pancreatic acinar cell.
A transcutaneous vaccination system using a hydrogel patch for viral and bacterial infection.
A transsynaptic autoradiographic study of the pathways controlling the extraocular eye muscles, using [125I]B-IIb tetanus toxin fragment.
A v-SNARE participates in synaptic vesicle formation mediated by the AP3 adaptor complex.
A vaccination strategy incorporating DNA priming and mucosal boosting using tetanus toxin fragment C (TetC).
A VLP for validation of the Plasmodium falciparum circumsporozoite protein junctional epitope for vaccine development.
A?42 oligomers selectively disrupt neuronal calcium release.
Aberrant Timm-stained fibres in the dentate gyrus following tetanus toxin-induced seizures in the rat.
Ability of healthcare workers to recall previous receipt of tetanus-containing vaccination.
Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization.
Accuracy of secondary structure and solvent accessibility predictions for a clostridial neurotoxin C-fragment.
Accurate quantification of tetanus neurotoxin-induced focal spasticity in mice using complex running wheels.
ACETYLCHOLINE LIBERATED FROM THE NERVE-MUSCLE PREPARATION IN TETANUS TOXIN POISONING.
Acetylcholinesterase in neural tube defects: a model using chick embryo amniotic fluid.
Acid secretion of parietal cells is paralleled by a redistribution of NSF and alpha, beta-SNAPs and inhibited by tetanus toxin.
Acidic and basic fibroblast growth factors delay the maturation of neural crest-derived neurons.
Acidification of the cytosol inhibits the uptake of tetanus toxin in NG108-15 and NBr-10A neurohybridoma cells.
Acrosomal Swelling and Membrane Docking Are Required for Hybrid Vesicle Formation During the Human Sperm Acrosome Reaction.
Action of adrenaline on tetanus toxin.
Action of botulinum A toxin and tetanus toxin on synaptic transmission.
Action of tetanus toxin in the cerebral cortex.
Action of tetanus toxin on brain and liver mitochondria of resistant and susceptible animals.
Action of tetanus toxin on brain, liver and muscle mitochondria from resistant and susceptible species.
Action of tetanus toxin on cholinergic neuroblastoma X glioma hybrid cells: selective blockade of Ca spikes.
Action of tetanus toxin on conditioning of spinal motoneurons.
Activation of phospholipases A2 and D of a human neuroblastoma cell line (LA-N-2) by N-dodecyl-L-lysine amide (compound 24), a putative G protein activator: characteristics of inhibition by (-)-nicotine.
Activation of signal transduction pathways involving trkA, PLCgamma-1, PKC isoforms and ERK-1/2 by tetanus toxin.
Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons.
Activation of the alternative complement pathway by the immune precipitate formed with F(ab')2 fragment of human IgG antibody.
Activation of the tonic GABAC receptor current in retinal bipolar cell terminals by nonvesicular GABA release.
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes.
Active immunization against tetanus in guinea-pigs. An attempt to evaluate "rapid immunization" with tetanus vaccine.
Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity.
Activity-dependent changes in partial VAMP complexes during neurotransmitter release.
Activity-dependent development of callosal projections in the somatosensory cortex.
Activity-dependent regulation of synaptic size in Drosophila neuromuscular junctions.
Activity-Dependent Secretion of Synaptic Organizer Cbln1 from Lysosomes in Granule Cell Axons.
Acute botulinum-like intoxication by tetanus neurotoxin in mice.
Adaptation of the nisin-controlled expression system in Lactobacillus plantarum: a tool to study in vivo biological effects.
Adaptive B cell responses in rituximab-treated diffuse large B cell lymphoma patients during complete remission.
Adenoviral clostridial light chain gene-based synaptic inhibition through neuronal synaptobrevin elimination.
Adherence of botulinum and tetanus neurotoxins to synaptosomal proteins.
Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.
Adjuvant effect of non-toxic mutants of E. coli heat-labile enterotoxin following intranasal, oral and intravaginal immunization.
Adjuvant properties and colonization potential of adhering and non-adhering Lactobacillus spp following oral administration to mice.
Adjuvant properties of thermal component of hyperthermia enhanced transdermal immunization: effect on dendritic cells.
Adoptive immunotherapy in canine chimeras.
Adsorption of tetanus toxin by brain tissue.
ADSORPTION OF TETANUS TOXIN BY SUB-CELLULAR FRACTIONS OF RABBIT BRAIN HOMOGENATE.
Adult human retinal cells in culture. Identification of cell types and expression of differentiated properties.
Affinity chromatographic purification and characterization of two iodinated tetanus toxin fractions exhibiting different binding properties.
Affinity chromatography of tetanus toxin, tetanus toxoid, and botulinum A toxin on synaptosomes, and differentiation of their acceptors.
Affinity purification of tetanus toxin using polyclonal and monoclonal antibody immunoadsorbents.
Affinity purified tetanus toxin binds to isolated chromaffin granules and inhibits catecholamine release in digitonin-permeabilized chromaffin cells.
Affinity-purified tetanus neurotoxin interaction with synaptic membranes: properties of a protease-sensitive receptor component.
Afterdischarges following F waves observed in a patient with tetanus.
All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A.
alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis.
Altered dentate filtering during the transition to seizure in the rat tetanus toxin model of epilepsy.
Altered electrical properties in Drosophila neurons developing without synaptic transmission.
Altered expression of the voltage-gated calcium channel subunit ?2?-1: A comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.
Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks.
Altered synaptic development and active zone spacing in endocytosis mutants.
Amino Acid Analysis and Molecular Weight Determination of Tetanus Toxin.
Ammonium chloride and methylamine hydrochloride antagonize clostridial neurotoxins.
Amphiphysin I is associated with coated endocytic intermediates and undergoes stimulation-dependent dephosphorylation in nerve terminals.
Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca2+, guanosine 5'-[gamma-thio]triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin.
An alternative treatment approach in tetanus: Botulinum toxin.
An animal model to study the clinical significance of interictal spiking.
An anti-CD19 antibody coupled to a tetanus toxin peptide induces efficient Fas ligand (FasL)-mediated cytotoxicity of a transformed human B cell line by specific CD4+ T cells.
An antigenic polypeptide fragment isolated from tetanus toxin: chemical characterization, binding to gangliosides and retrograde axonal transport in various neuron systems.
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
An attempt to activate the spontaneous motility in chick embryos with tetanus toxin.
An Aß concatemer with altered aggregation propensities.
An effective toxoid from tetanus toxin prepared by stepwise iodination of purified toxin.
An effective, simple and low-cost pretreatment for culture clarification in tetanus toxoid production.
An efficacious recombinant subunit vaccine against the salmonid rickettsial pathogen Piscirickettsia salmonis.
An electron microscopic study of the effects of tetanus toxin on motoneurons of the rat spinal cord.
An ELISA for quantitation of tetanus toxin.
An example of immunodominance: engagement of synonymous TCR by invariant CDR3 beta.
An HLA-DRB alpha-helix motif shared by DR11 and DR8 alleles is implicated in the pluriallelic restriction of peptide-specific T-cell lines.
An immunohistochemical study on a tetanus fatal case using toxin fragment C (TTC). Should it be a useful diagnostic tool?
An in vitro assay for detection of tetanus neurotoxin activity: using antibodies for recognizing the proteolytically generated cleavage product.
An intact interchain disulfide bond is required for the neurotoxicity of tetanus toxin.
An Investigation into the Nature of the Changes produced in the Nerve-cells of the Cerebral Cortex by the Action of Tetanus Toxin.
An observational study of antibody responses to a primary or subsequent pertussis booster vaccination in Australian healthcare workers.
An olfactory circuit increases the fidelity of visual behavior.
An oligoclonal combination of human monoclonal antibodies able to neutralize tetanus toxin in vivo.
An optical surface plasmon resonance biosensor for determination of tetanus toxin.
An optogenetic approach in epilepsy.
Analyses of the co-localization of cellubrevin and the GLUT4 glucose transporter in rat and human insulin-responsive tissues.
Analysis and isolation of embryonic mammalian neurons by fluorescence-activated cell sorting.
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties.
Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR.
Analysis of Signaling Endosome Composition and Dynamics Using SILAC in Embryonic Stem Cell-Derived Neurons.
Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma.
Analysis of the immune response to papain digestion products of tetanus toxin.
Analysis of the structure and expression of the VAMP family of synaptic vesicle proteins.
Anatomically discrete functional effects of adenoviral clostridial light chain gene-based synaptic inhibition in the midbrain.
Animal models of the epilepsies.
Antagonism of synaptic inhibition in the rat substantia nigra by tetanus toxin [proceedings].
Antagonism of the intracellular action of botulinum neurotoxin type A with monoclonal antibodies that map to light-chain epitopes.
Anti-B-50 (GAP-43) antibodies decrease exocytosis of glutamate in permeated synaptosomes.
Anti-tetanus toxoid antibody production and protection against lethal doses of tetanus toxin in hu-PBL-SCID mice.
Antibodies against rat brain vesicle-associated membrane protein (synaptobrevin) prevent inhibition of acetylcholine release by tetanus toxin or botulinum neurotoxin type B.
Antibodies against the light chain of tetanus toxin in human sera.
Antibodies to shiga holotoxin and to two synthetic peptides of the B subunit in sera of patients with Shigella dysenteriae 1 dysentery.
Antibodies to tetanus toxin in black infants in South Africa.
Antibody against cholesteryl ester transfer protein (CETP) elicited by a recombinant chimeric enzyme vaccine attenuated atherosclerosis in a rabbit model.
Antibody microarrays for native toxin detection.
Antibody modulation of antigen presentation: positive and negative effects on presentation of the tetanus toxin antigen via the murine B cell isoform of FcgammaRII.
Antibody production of a human EBV-transformed B cell line and its heterohybridoma and trioma cell line descendants in different culture systems.
Antibody response of pregnant women to two different absorbed tetanus toxoids.
Antibody response to diphtheria, tetanus, and poliomyelitis vaccines in relation to the number of CD4+ T lymphocytes in adults infected with human immunodeficiency virus.
Antibody response to Haemophilus influenzae type b vaccine in relation to the number of CD4+ T lymphocytes in adults infected with human immunodeficiency virus.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Antidepressant effects of C-Terminal domain of the heavy chain of tetanus toxin in a rat model of depression.
Antiepileptic and antiamnesic effect of carbamazepine in experimental limbic epilepsy.
Antiepileptic effect of gap-junction blockers in a rat model of refractory focal cortical epilepsy.
Antigen recognition by MHC-incompatible cells of a human mismatched chimera.
Antigen-bound C3b and C4b enhance antigen-presenting cell function in activation of human T-cell clones.
Antigen-dependent regulation of IgE antibody production by human antigen-specific B cells.
Antigen-presenting human T cells and antigen-presenting B cells induce a similar cytokine profile in specific T cell clones.
Antigen-processing organelles from DRB1*1101 and DRB1*1104 B cell lines display a differential degradation activity.
Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs.
Antigen-specific primary immune response of human B-lymphocytes after in vitro immunization with GM3 ganglioside.
Antigen-specific T cells with monogamous or promiscuous restriction patterns are sensitive to different HLA-DR beta chain substitutions.
Antigenic substructure of tetanus neurotoxin.
ANTIGENIC THRESHOLDS OF ANTITOXIN RESPONSES ELICITED IN IRRADIATED MICE WITH COMPLEXES OF TETANUS TOXIN AND SPECIFIC ANTIBODY.
Antigenicity and immunogenicity of multiple antigen peptides (MAP) containing P. vivax CS epitopes in Aotus monkeys.
Antitoxin's effect on tetanus toxin induced sphincter pupillae paralysis in the rabbit.
Application of an in vitro endopeptidase assay for detection of residual toxin activity in tetanus toxoids.
Application of anti-peptide antibodies to the assignment of the inter-chain disulphide bond in tetanus toxin.
Application of NMR methods to identify detection reagents for use in development of robust nanosensors.
Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells.
Approaches for studying the pathogenic T cells in autoimmune patients.
Are DNA-based vaccines useful for protection against secreted bacterial toxins? Tetanus toxin test case.
Arrangement of disulfide bridges and positions of sulfhydryl groups in tetanus toxin.
Asparaginase Display of Human Cholesteryl Ester Transfer Protein (CETP) B Cell Epitopes for Inducing High Titers of Anti-CETP Antibodies In Vivo.
Asparaginase display of polypeptides in the periplasm of Escherichia coli: potential rapid pepscan technique for antigen epitope mapping.
Asparagine deamidation perturbs antigen presentation on class II major histocompatibility complex molecules.
Aspartate release from rat hippocampal synaptosomes.
Assessment of a vaccinia virus vectored multi-epitope live vaccine candidate for Plasmodium falciparum.
Astrocytes contribute to gamma oscillations and recognition memory.
Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity.
Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons.
Astrocytic plasticity and patterned oxytocin neuronal activity: dynamic interactions.
Astroglial cells provide a template for the positioning of developing cerebellar neurons in vitro.
Asymmetric non-precipitating antibodies in commercial hyperimmune gamma-globulin for therapeutic use.
Asynchronous Distributed Multielectrode Microstimulation Reduces Seizures in the Dorsal Tetanus Toxin Model of Temporal Lobe Epilepsy.
At least three sequential steps are involved in the tetanus toxin-induced block of neuromuscular transmission.
ATP potently modulates anion channel-mediated excitatory amino acid release from cultured astrocytes.
ATP release from pure cholinergic synaptosomes is not blocked by tetanus toxin.
Attempt to curtail the observation period of mice in the tetanus vaccine potency tests.
Attenuated deltaguaBA Salmonella typhi vaccine strain CVD 915 as a live vector utilizing prokaryotic or eukaryotic expression systems to deliver foreign antigens and elicit immune responses.
Attenuated Salmonella typhimurium SL3261 as a vaccine vector for recombinant antigen in rabbits.
Attenuation of inhibitory processes in the central nervous system by tetanus toxin: an in vitro study on rat hippocampal slices.
Autism and Clostridium tetani.
Autonomic nervous system dysfunction in children with severe tetanus: dissociation of cardiac and vascular sympathetic control.
Autonomic nervous system dysfunction in severe tetanus: current perspectives.
Autonomic nervous system instability, tetanic necrosis of the heart and myocardial TNFalpha expression in a tetanus fatal case.
Avian eyelid assay, a new diagnostic method for detecting botulinum neurotoxin serotypes A, B and E.
Axonal Transport as an In Vivo Biomarker for Retinal Neuropathy.
Axonal transport in neurological disease.
B lymphocytes acquire and present intracellular antigens that have relocated to the surface of apoptotic target cells.
Bacillus subtilis : A temperature resistant and needle free delivery system of immunogens.
Bacterial antigen expression is an important component in inducing an immune response to orally administered salmonella-delivered DNA vaccines.
Bacterial inhibition of phagocytosis.
Bacterial intracellularly active toxins: Membrane localisation of the active domain.
Bacterial protease inhibitors.
Bacterial spores as heat stable vaccine vehicles.
Bacterial spores as vaccine vehicles.
Bacterial toxin's DNA vaccine serves as a strategy for the treatment of cancer, infectious and autoimmune diseases.
Bacterial toxins with intracellular protease activity.
Bacterial Toxins, Current Perspectives.
Bacterial toxins.
Bacterial toxins: an overview on bacterial proteases and their action as virulence factors.
Bafilomycin A1 inhibits the action of tetanus toxin in spinal cord neurons in cell culture.
Barium and calcium stimulate secretion from digitonin-permeabilized bovine adrenal chromaffin cells by similar pathways.
Basic immunological aspects of botulinum toxin therapy.
Bayesian Optimization of Asynchronous Distributed Microelectrode Theta Stimulation and Spatial Memory.
BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury.
BDNF induces glutamate release in cerebrocortical nerve terminals and in cortical astrocytes.
BDNF Overexpression Enhances the Preconditioning Effect of Brief Episodes of Hypoxia, Promoting Survival of GABAergic Neurons.
Behavioral and neurochemical repercussions of hippocampal network activity blockade during the neonatal period.
Behaviour of Paramecium aurelia in solutions of purified and fluorescent labelled tetanus neurotoxin.
Behavioural and neuropathological effects produced by tetanus toxin injected into the hippocampus of rats.
Behavioural correlates of an experimental hippocampal epileptiform syndrome in rats.
Benzathine penicillin, metronidazole and benzyl penicillin in the treatment of tetanus: a randomized, controlled trial.
Beta-amino-thiols inhibit the zinc metallopeptidase activity of tetanus toxin light chain.
Binding and cleavage (BINACLE) assay for the functional in vitro detection of tetanus toxin: Applicability as alternative method for the safety testing of tetanus toxoids during vaccine production.
Binding and transcytosis of botulinum neurotoxin by polarized human colon carcinoma cells.
Binding characteristics of 125I-labelled tetanus toxin to primary tissue cultures from mouse embryonic CNS.
Binding of botulinum and tetanus neurotoxins to ganglioside GT1b and derivatives thereof.
Binding of ganglioside by the chains of tetanus toxin.
Binding of single substituted promiscuous and designer peptides to purified DRB1*0101.
Binding of tetanus toxin to somatic neural hybrid cells with varying ganglioside composition.
Bioaccumulative potential and toxicity of endosulfan insecticide to non-target animals.
Biochemical analyses of the inhibition of catecholamine release by tetanus toxin in digitonin-permeabilized chromaffin cells.
Bioinformatic discovery of a toxin family in Chryseobacterium piperi with sequence similarity to botulinum neurotoxins.
Biological properties the novel application of N-trimethyl chitosan nanospheres as a stabilizer and preservative in tetanus vaccine.
Black tea extract, thearubigin fraction, counteract the effects of botulinum neurotoxins in mice.
Black tea extract, thearubigin fraction, counteracts the effect of tetanus toxin in mice.
Black widow spider toxin-induced calcium fluxes and transmitter release in a neurosecretory cell line.
Blocking Ca(2+)-dependent synaptic release delays motoneuron differentiation in the rat spinal cord.
Blocking effects of tetanus toxin and its fragment [A-B] on the excitatory and inhibitory synapses of the spinal motoneurone of the cat.
Blocking sensory inputs to identified antennal glomeruli selectively modifies odorant perception in Drosophila.
Blocking synaptic transmission with tetanus toxin light chain reveals modes of neurotransmission in the PDF-positive circadian clock neurons of Drosophila melanogaster.
Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.
BotR/A and TetR are alternative RNA polymerase sigma factors controlling the expression of the neurotoxin and associated protein genes in Clostridium botulinum type A and Clostridium tetani.
Botulinal neurotoxin C1 complex genes, clostridial neurotoxin homology and genetic transfer in Clostridium botulinum.
Botulinum A and the light chain of tetanus toxins inhibit distinct stages of Mg.ATP-dependent catecholamine exocytosis from permeabilised chromaffin cells.
Botulinum A like type B and tetanus toxins fulfils criteria for being a zinc-dependent protease.
Botulinum A neurotoxin inhibits non-cholinergic synaptic transmission in mouse spinal cord neurons in culture.
Botulinum A neurotoxin unlike tetanus toxin acts via a neuraminidase sensitive structure.
Botulinum A toxin and tetanus toxin do not affect presynaptic membrane currents in mammalian motor nerve endings.
Botulinum and Tetanus Neurotoxin-Induced Blockade of Synaptic Transmission in Networked Cultures of Human and Rodent Neurons.
Botulinum and Tetanus Neurotoxins.
Botulinum E toxin light chain does not cleave SNAP-23 and only partially impairs insulin stimulation of GLUT4 translocation in 3T3-L1 cells.
Botulinum neurotoxin - from laboratory to bedside.
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25.
Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin.
Botulinum neurotoxin E-insensitive mutants of SNAP-25 fail to bind VAMP but support exocytosis.
Botulinum neurotoxin type B (strain 657): partial sequence and similarity with tetanus toxin.
Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin.
Botulinum neurotoxin type G proteolyses the Ala81-Ala82 bond of rat synaptobrevin 2.
Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.
Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
Botulinum toxin and tetanus toxin recognize similar membrane determinants.
Botulinum versus tetanus neurotoxins: why is botulinum neurotoxin but not tetanus neurotoxin a food poison?
Bradycardia of central origin produced by injections of tetanus toxin into the vagus nerve.
Bradykinin-induced astrocyte\#8211;neuron signalling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels.
Brain hypometabolism in a model of chronic focal epilepsy in rat neocortex.
Brain-derived neurotrophic factor enhances depolarization-evoked glutamate release in cultured cortical neurons.
Brain-derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C-terminal fragment fusion proteins in mature mouse motor nerve terminals.
Brain-derived neurotrophic factor induces rapid morphological changes in dendritic spines of olfactory bulb granule cells in cultured slices through the modulation of glutamatergic signaling.
Breaking B-cell tolerance and CTL tolerance in three OVA-transgenic mouse strains expressing different levels of OVA.
Brevetoxin-induced autocrine excitotoxicity is associated with manifold routes of Ca2+ influx.
C fragment of tetanus toxin hybrid proteins evaluated for muscle-specific transsynaptic mapping of spinal motor circuitry in the newborn mouse.
C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons.
C-terminal half of tetanus toxin fragment C is sufficient for neuronal binding and interaction with a putative protein receptor.
C. botulinum neurotoxin types A and E: isolated light chain breaks down into two fragments. Comparison of their amino acid sequences with tetanus neurotoxin.
C3b complexation diversifies naturally processed T cell epitopes.
C3b covalently associated to tetanus toxin modulates TT processing and presentation by U937 cells.
Ca permeable AMPA receptor induced long-term potentiation requires PI3/MAP kinases but not Ca/CaM-dependent kinase II.
Ca(2+) influx and cAMP elevation overcame botulinum toxin A but not tetanus toxin inhibition of insulin exocytosis.
Ca(2+)-independent but voltage-dependent secretion in mammalian dorsal root ganglion neurons.
Ca-dependent nonsecretory vesicle fusion in a secretory cell.
Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinum toxin A and C, but not tetanus toxin.
Ca2+-dependent regulation of synaptic SNARE complex assembly via a calmodulin- and phospholipid-binding domain of synaptobrevin.
Ca2+/calmodulin transfers the membrane-proximal lipid-binding domain of the v-SNARE synaptobrevin from cis to trans bilayers.
Calcium can disrupt the SNARE protein complex on sea urchin egg secretory vesicles without irreversibly blocking fusion.
Calcium-dependent endogenous proteolysis of the vesicle proteins synaptobrevin and synaptotagmin.
Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part I: trans-Golgi network-derived organelles undergo regulated exocytosis.
Calcium-regulated exocytosis is required for cell membrane resealing.
Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis.
Calmodulin is involved in catecholamine secretion from digitonin-permeabilized bovine adrenal medullary chromaffin cells.
Calmodulin-dependent regulation of a lipid binding domain in the v-SNARE synaptobrevin and its role in vesicular fusion.
cAMP increases surface expression of NKCC2 in rat thick ascending limbs: role of VAMP.
cAMP signalling in mushroom bodies modulates temperature preference behaviour in Drosophila.
Candidate gustatory interneurons modulating feeding behavior in the Drosophila brain.
Candidate live, attenuated Salmonella enterica serotype Typhimurium vaccines with reduced fecal shedding are immunogenic and effective oral vaccines.
CAR-Associated Vesicular Transport of an Adenovirus in Motor Neuron Axons.
CAR-associated vesicular transport of an adenovirus in motor neuron axons.
Carbohydrate recognition by pentadecapeptide ligands for a series of sialylated oligosaccharides.
Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: Bradyarrhythmias, tachycardias, and prolonged interictal QT interval.
Cardiovascular effects of tetanus toxin after systemic and intraventricular administration in rats.
Cardiovascular instability and baroreflex activity in a patient with tetanus.
Carrier-induced epitope-specific regulation and its bypass in a protein-protein conjugate.
Carrier-mediated GABA release activates GABA receptors on hippocampal neurons.
Cathepsin E regulates the presentation of tetanus toxin C-fragment in PMA activated primary human B cells.
Cattle immune responses to tetanus toxoid elicited by recombinant S. typhimurium vaccines or tetanus toxoid in alum or Freund's adjuvant.
CD34+-derived CD11c+ + + BDCA-1+ + CD123+ + DC: expansion of a phenotypically undescribed myeloid DC1 population for use in adoptive immunotherapy.
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide.
Cell entry strategy of clostridial neurotoxins.
Cell lineages in peripheral nervous system ontogeny: medium-induced modulation of neuronal phenotypic expression in neural crest cell cultures.
Cell surface and cytoskeletal antigens in cerebral cell cultures after chloroform-methanol delipidation.
Cell surface changes accompanying the neural differentiation of an embryonal carcinoma cell line.
Cell surface markers for distinguishing different types of rat dorsal root ganglion cells in culture.
Cell surface-exposed tetanus toxin fragment C produced by recombinant Bacillus anthracis protects against tetanus toxin.
Cell swelling-induced insulin secretion from INS-1E cells is inhibited by extracellular Ca2+ and is tetanus toxin resistant.
Cell swelling-induced signaling for insulin secretion bypasses steps involving G proteins and PLA2 and is N-ethylmaleimide insensitive.
Cell type-specific markers for human glial and neuronal cells in culture.
Cell type-specificity of epidermal growth factor (EGF) binding in primary cultures of early postnatal mouse cerebellum.
Cell types and coincident synapses in the ellipsoid body of Drosophila.
Cell-Based Reporter Release Assay to Determine the Potency of Proteolytic Bacterial Neurotoxins.
Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture.
Cells with neuronal properties in permanent cultures of quail embryo neuroretinas infected with Rous sarcoma virus.
Cellubrevin is a resident protein of insulin-sensitive GLUT4 glucose transporter vesicles in 3T3-L1 adipocytes.
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein.
Cellular identification of water gustatory receptor neurons and their central projection pattern in Drosophila.
Cellular mechanisms of serotonin 5-HT2A receptor-mediated cGMP formation: the essential role of glutamate.
Cellular responses to acute injury: the role of the plasma membrane in cell response to two clostridial toxins.
Central complex substructures are required for the maintenance of locomotor activity in Drosophila melanogaster.
Central effects of tetanus and botulinum neurotoxins.
Central effects of tetanus toxin in adult cockerels.
Cephalic tetanus from penetrating orbital wound.
Cerebellar plasma membrane proteins and their antisera.
Chains and fragments of tetanus toxin, and their contribution to toxicity.
Chains and fragments of tetanus toxin. Separation, reassociation and pharmacological properties.
Changes in blood chemistry and liver histopathology of rabbits during experimental tetanus toxicity.
Changes in neuromuscular transmission in slow and fast skeletal muscles of the mouse after local injection of tetanus toxin.
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.
Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding.
Characterisation of botulinum toxins type A and B, by matrix-assisted laser desorption ionisation and electrospray mass spectrometry.
Characteristics of tetanus toxin and its exploitation in neurodegenerative studies.
Characteristics of toxin-neutralization by anti-tetanus human monoclonal antibodies directed against the three functional domains [A], [B] and [C] of the tetanus toxin molecule and a reliable method for evaluating the protective effects of monoclonal antibodies.
Characterization and evaluation of the enzymatic activity of tetanus toxin submitted to cobalt-60 gamma radiation.
Characterization and immunological activity of different forms of recombinant secreted Hc of botulinum neurotoxin serotype B products expressed in yeast.
Characterization and visualization of tetanus toxin acceptors on adrenal chromaffin granules.
Characterization of brevetoxin (PbTx-3) exposure in neurons of the anoxia-tolerant freshwater turtle (Trachemys scripta).
Characterization of crystalline filtrate tetanus toxin.
Characterization of fragment C and tetanus toxin binding to rat brain membranes.
Characterization of human hybridomas secreting antibody to tetanus toxoid.
Characterization of isolated mouse cerebellar cell populations in vitro.
Characterization of mitotic neurons derived from adult rat hypothalamus and brain stem.
Characterization of monoclonal antibody 3G5 and utilization of this antibody to immobilize pancreatic islet cell gangliosides in a solid phase radioassay.
Characterization of neutralizing monoclonal antibodies directed against tetanus toxin fragment C.
Characterization of production processes for tetanus and diphtheria anatoxins.
Characterization of receptor-mediated signal transduction by Escherichia coli type IIa heat-labile enterotoxin in the polarized human intestinal cell line T84.
Characterization of recombinant tetanus toxin derivatives suitable for vaccine development.
Characterization of rotavirus specific B cells and their relation with serological memory.
Characterization of SNARE protein expression in beta cell lines and pancreatic islets.
Characterization of tetanus toxin binding to rat brain membranes. Evidence for a high-affinity proteinase-sensitive receptor.
Characterization of tetanus toxin, neat and in culture supernatant, by electrospray mass spectrometry.
Characterization of the binding and internalization of tetanus toxin in a neuroblastoma hybrid cell line.
Characterization of the channel properties of tetanus toxin in planar lipid bilayers.
Characterization of the cholinergic neuronal differentiation of the human neuroblastoma cell line LA-N-5 after treatment with retinoic acid.
Characterization of the receptor-binding domain of tetanus toxin.
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.
Chelation of zinc antagonizes the neuromuscular blocking properties of the seven serotypes of botulinum neurotoxin as well as tetanus toxin.
Chemical assay of the tetanus toxin receptor in nervous tissue.
Chemical characterization of tetanus toxin and toxoid. Amino acid composition, number of SH and S-S groups and N-terminal amino acid.
Chemical models of epilepsy with some reference to their applicability in the development of anticonvulsants.
Chemoenzymatic synthesis of immunogenic meningococcal group C polysialic acid-tetanus Hc fragment glycoconjugates.
Chitosan-based gene delivery vectors targeted to the peripheral nervous system.
Chronic effect of tetanus toxin applied locally to the cerebral cortex of the dog.
Chronic Epileptic Foci in Neocortex: In Vivo and In Vitro Effects of Tetanus Toxin.
Chronic epileptic foci in vitro in hippocampal slices from rats with the tetanus toxin epileptic syndrome.
Chronic epileptic foci induced by intracranial tetanus toxin.
Chronic focal epilepsy induced by intracerebral tetanus toxin.
Chronic focal epilepsy induced by microinjection of tetanus toxin into the cat motor cortex.
Chronic restraint stress induces severe disruption of the T-cell specific response to tetanus toxin vaccine.
Chronic tetanus: clinical report and histochemistry of muscle.
Chronic/semichronic limbic epilepsy produced by microinjection of tetanus toxin in cat hippocampus.
Chronological changes in inflammatory cytokines immunoreactivities in the mouse hippocampus after systemic administration of high dosage of tetanus toxin.
Circle of life of secretory vesicles in gastric enterochromaffin-like cells.
Circumventing Brain Barriers: Nanovehicles for Retroaxonal Therapeutic Delivery.
Cleavage of cellubrevin by tetanus toxin does not affect fusion of early endosomes.
Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin.
Cleavage of SNAP-25 and VAMP-2 impairs store-operated Ca2+ entry in mouse pancreatic acinar cells.
Clinical and immunologic responses to the capsular polysaccharide of Haemophilus influenzae type b alone or conjugated to tetanus toxoid in 18- to 23-month-old children.
Clinical Profile and Outcome of Pediatrics Tetanus: The Experience of a Tertiary Hospital in Ethiopia.
Cloned human teratoma cells differentiate into neuron-like cells and other cell types in retinoic acid.
Cloning and expression of functional fragment C of tetanus toxin.
Cloning and Expression of Targeting CuZn-SOD to Central Nervous System.
Cloning and Expression of Tetanus Toxin Fragment C in E.coli.
Cloning in Escherichia coli of the enterotoxin gene from Clostridium perfringens type A.
Cloning of a Clostridium botulinum type B toxin gene fragment encoding the N-terminus of the heavy chain.
Cloning of a DNA fragment encoding the 5'-terminus of the botulinum type E toxin gene from Clostridium butyricum strain BL6340.
Cloning of the structural gene for Clostridium botulinum type C1 toxin and whole nucleotide sequence of its light chain component.
Cloning, nucleotide sequencing, and expression of tetanus toxin fragment C in Escherichia coli.
Clostridial neurotoxin light chains: devices for SNARE cleavage mediated blockade of neurotransmission.
Clostridial neurotoxins and substrate proteolysis in intact neurons: botulinum neurotoxin C acts on synaptosomal-associated protein of 25 kDa.
Clostridial neurotoxins as a drug delivery vehicle targeting nervous system.
Clostridial neurotoxins as tools to investigate the molecular events of neurotransmitter release.
Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion.
Clostridial neurotoxins: from toxins to therapeutic tools?
Clostridial Neurotoxins: Mechanism of SNARE Cleavage and Outlook on Potential Substrate Specificity Reengineering.
Clostridial Neurotoxins: Mode of Substrate Recognition and Novel Therapy Development.
Clostridial neurotoxins: new tools for dissecting exocytosis.
Clostridial toxins.
Clostridium neurotoxin fragments as potential targeting moieties for liposomal gene delivery to the CNS.
Clostridium neurotoxins influence serotonin uptake and release differently in rat brain synaptosomes.
Clostridium tetani growth and toxin production in the intestines of germfree rats.
Co-dominant and reciprocal T-helper cell activity of epitopic sequences and formation of junctional B-cell determinants in synthetic T:B chimeric immunogens.
Co-expression of tetanus toxin fragment C in Escherichia coli with thioredoxin and its evaluation as an effective subunit vaccine candidate.
Cocaine-Induced Synaptic Alterations in Thalamus to Nucleus Accumbens Projection.
Colinear synthesis of an antigen-specific B-cell epitope with a 'promiscuous' tetanus toxin T-cell epitope: a synthetic peptide immunocontraceptive.
Colonization of the intestinal tract of mice with Clostridium tetani.
Combination of DTP and Haemophilus influenzae type b conjugate vaccines can affect laboratory evaluation of potency and immunogenicity.
Combination therapy of hepatocellular carcinoma by DNA shuffling-based VEGF vaccine and doxorubicin.
Combining Well-Tempered Metadynamics Simulation and SPR Assays to Characterize the Binding Mechanism of the Universal T-Lymphocyte Tetanus Toxin Epitope TT830-843.
Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin.
Comparative analysis of tetanus antitoxin titers of sera from immunized mice and guinea pigs determined by toxin neutralization test and enzyme-linked immunosorbent assay.
Comparative genomic analysis of a neurotoxigenic Clostridium species using partial genome sequence: Phylogenetic analysis of a few conserved proteins involved in cellular processes and metabolism.
Comparative human and mouse antibody responses against tetanus toxin at clonal level.
Comparative Immunogenicity of the Tetanus Toxoid and Recombinant Tetanus Vaccines in Mice, Rats, and Cynomolgus Monkeys.
Comparative in vitro and in vivo assessment of toxin neutralization by anti-tetanus toxin monoclonal antibodies.
Comparative pathogenomics of Clostridium tetani.
Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons.
Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age.
Comparison of abilities of Salmonella enterica serovar typhimurium aroA aroD and aroA htrA mutants to act as live vectors.
Comparison of adjuvant activities of aluminium phosphate, calcium phosphate and stearyl tyrosine for tetanus toxoid.
Comparison of carrier proteins to conjugate malaria transmission blocking vaccine antigens, Pfs25 and Pfs230.
Comparison of Corynebacterium parvum and Bordetella pertussis with Freund's complete adjuvant as immunopotentiators for beta-human chorionic gonadotropin linked to an atoxic fragment of tetanus toxin.
Comparison of Passive Hemagglutination with Turkey Erythrocyte Assay, Enzyme-Linked Immunosorbent Assay, and Counterimmunoelectrophoresis Assay for Serological Evaluation of Tetanus Immunity.
Comparison of peptide and superantigen-induced anergy in a peptide-specific polyclonal human T cell line.
Comparison of the abilities of different attenuated Salmonella typhimurium strains to elicit humoral immune responses against a heterologous antigen.
Comparison of the binding characteristics of two different preparations of tetanus toxin to rat brain membranes.
Comparison of the immune responses induced by local immunizations with recombinant Lactobacillus plantarum producing tetanus toxin fragment C in different cellular locations.
Comparison of the intracellular effects of clostridial neurotoxins on exocytosis from streptolysin O-permeabilized rat pheochromocytoma (PC 12) and bovine adrenal chromaffin cells.
Comparison of the pH-induced conformational change of different clostridial neurotoxins.
Compensatory dendritic growth of CA1 pyramidal cells following growth impairment in the neonatal period.
Competition from newborn granule cells does not drive axonal retraction of silenced old granule cells in the adult hippocampus.
Complement activation by polyclonal immunoglobulin G1 and G2 antibodies against Staphylococcus aureus, Haemophilus influenzae type b, and tetanus toxoid.
Complement C3b fragment covalently linked to tetanus toxin increases lysosomal sodium dodecyl sulfate-stable HLA-DR dimer production.
Complex ganglioside expression and tetanus toxin binding by PC12 pheochromocytoma cells.
Computerized analysis of ionic channel multi-state conductance in planar lipid bilayers.
Concanavalin A inhibits nicotinic acetylcholine receptor function in cultured chick ciliary ganglion neurons.
Concomitant administration of diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) with pentavalent rotavirus vaccine in Japanese infants.
Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity.
Conditional genetic transsynaptic tracing in the embryonic mouse brain.
Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission.
Conformational and molecular weight studies of tetanus toxin and its major peptides.
Conjugate Vaccines from Bacterial Antigens by Squaric Acid Chemistry: A Closer Look.
Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR.
Connexin 43 mRNA expression in two experimental models of epilepsy.
Construction and immunogenicity in mice of attenuated Salmonella typhi expressing Plasmodium falciparum merozoite surface protein 1 (MSP-1) fused to tetanus toxin fragment C.
Construction of a genetically defined Salmonella typhi Ty2 aroA, aroC mutant for the engineering of a candidate oral typhoid-tetanus vaccine.
Construction of hybrid proteins that migrate retrogradely and transynaptically into the central nervous system.
Construction of scFv library of human antibodies against tetanus toxin.
Construction, expression, and immunogenicity of multiple tandem copies of the Schistosoma mansoni peptide 115-131 of the P28 glutathione S-transferase expressed as C-terminal fusions to tetanus toxin fragment C in a live aro-attenuated vaccine strain of Salmonella.
Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella.
Contained and high-level production of recombinant protein in plant chloroplasts using a temporary immersion bioreactor.
Contribution of Fc fragment of monoclonal antibodies to tetanus toxin neutralization.
Control of antigen presentation by a single protease cleavage site.
CONVERSION OF HYDROLYSATE TETANUS TOXIN TO TOXOID.
Cooperative action of the light chain of tetanus toxin and the heavy chain of botulinum toxin type A on the transmitter release of mammalian motor endplates.
Cooperative binding of anti-tetanus toxin monoclonal antibodies: Implications for designing an efficient biclonal preparation to prevent tetanus toxin intoxication.
Cooperative exosite-dependent cleavage of synaptobrevin by tetanus toxin light chain.
Correlation analysis between frequencies of circulating antigen-specific IgG-bearing memory B cells and serum titers of antigen-specific IgG.
Correlation between CGRP immunoreactivity and firing activity in cat abducens motoneurons.
Corrigendum to "C Fragment of Tetanus Toxin Hybrid Proteins Evaluated for Muscle-specific Transsynaptic Mapping of Spinal Motor Circuitry in the Newborn Mouse" [Neuroscience 141(2) (2006) 803-816].
Cortically induced masticatory rhythm in masseter motoneurons after blocking inhibition by strychnine and tetanus toxin.
Courtship initiation is stimulated by acoustic signals in Drosophila melanogaster.
Covalent binding of C3b to tetanus toxin: influence on uptake/internalization of antigen by antigen-specific and non-specific B cells.
Covalent modification of synapsin I by a tetanus toxin-activated transglutaminase.
Covalent modifications of antitetanus F(ab')2 fragments with natural and synthetic polyamines and their effects on the antibody endocytosis in cultured HL60 cells.
CpG-Loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines.
Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen.
Cross reaction of tetanus and botulinum neurotoxins A and B and the boosting effect of botulinum neurotoxins A and B on a primary anti-tetanus antibody response.
Crystallization and preliminary X-ray analysis of tetanus neurotoxin C fragment.
Crystallization of a nonreplicating rotavirus vaccine candidate.
Crystallographic characterization of tetanus toxin fragment C.
Cultivation of mouse cerebellar cells in serum free, hormonally defined media: survival of neurons.
Cultured astrocytes express proteins involved in vesicular glutamate release.
Cultured neurones from the mature bovine mediobasal hypothalamus contain LHRH but not catecholamine.
CuZn superoxide dismutase (SOD-1):tetanus toxin fragment C hybrid protein for targeted delivery of SOD-1 to neuronal cells.
Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate.
Cytotoxic effects of a chimeric protein consisting of tetanus toxin light chain and anthrax toxin lethal factor in non-neuronal cells.
Decrease of muscle extensibility and reduction of sarcomere number in soleus muscle following a local injection of tetanus toxin.
Decreased dendritic spine density as a consequence of tetanus toxin light chain expression in single neurons in vivo.
Defining a region on tetanus toxin responsible for neuromuscular blockade.
Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression.
Delineation and comparison of ganglioside-binding epitopes for the toxins of Vibrio cholerae, Escherichia coli, and Clostridium tetani: evidence for overlapping epitopes.
Delineation of several DR-restricted tetanus toxin T cell epitopes.
Delivery of chemotherapeutic agents to the central nervous system.
Delivery of recombinant tetanus-superoxide dismutase proteins to central nervous system neurons by retrograde axonal transport.
DeltaguaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin.
Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases.
Dendritic shrinkage and dye-coupling between rat hippocampal CA1 pyramidal cells in the tetanus toxin model of epilepsy.
Density and distribution of Clostridium tetani in the soil.
Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy.
Depolarization, exocytosis and amino acid release evoked by hyposmolarity from cortical synaptosomes.
Depressed proliferative responses by peripheral blood mononuclear cells from early arthritis patients to mycobacterial heat shock protein 60.
Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus.
Design and construction of immune phage antibody library against Tetanus neurotoxin: Production of single chain antibody fragments.
Design of highly immunogenic liposomal constructs combining structurally independent B cell and T helper cell peptide epitopes.
Detection of abnormal cerebral excitability by coincident stimulation and recording.
Detection of bacterial toxins with monosaccharide arrays.
Detection of Clostridium botulinum toxin A using a fiber optic-based biosensor.
Detection of minimal disease in bone marrow of neuroblastoma patients by immunofluorescence.
Detection of the tetanus toxin gene by polymerase chain reaction: a case study.
Determination of immunity against tetanus infection by passive haemagglutination assay.
Detoxification of diphtheria and tetanus toxin with formaldehyde. Detection of protein conjugates.
Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus.
Development and validation of an anion-exchange LC-UV method for the quantification and purity determination of the DNA plasmid pDERMATT.
Development of a guinea-pig model for potency/immunogenicity evaluation of diphtheria, tetanus acellular pertussis (DTaP) and Haemophilus influenzae type b polysaccharide conjugate vaccines.
Development of a multi-epitope peptide vaccine inducing robust T cell responses against brucellosis using immunoinformatics based approaches.
Development of a nonantibiotic dominant marker for positively selecting expression plasmids in multivalent Salmonella vaccines.
Development of an animal model to assess the immunogenicity of single-dose tetanus and diphtheria vaccines based on controlled release from biodegradable polymer microspheres.
Development of an epitope-based vaccine inhibiting immune cells rolling and migration against atherosclerosis using in silico approaches.
Development of an operational synaptobrevin-based fluorescent substrate for tetanus neurotoxin quantification.
Development of chronic secondary epileptic foci following intrahippocampal injection of tetanus toxin in the rat.
Development of functional neurons from postnatal stem cells in vitro.
Development of high-specificity antibodies against renal urate transporters using genetic immunization.
Development of Thy-1 antigen on cerebellar neurons in culture.
Development of Vaccine Delivery Vehicles Based on Lactic Acid Bacteria.
Development, validation and acceptance of alternative methods in the quality control of vaccines: A case report.
Developmental and neurochemical specificity of neuronal deficits produced by electrical impulse blockade in dissociated spinal cord cultures.
Developmental changes in release properties of the CA3-CA1 glutamate synapse in rat hippocampus.
Developmental expression of cell type-specific markers in mouse cerebellar cells in vitro.
Developmental neuroplasticity: roles in early life seizures and chronic epilepsy.
DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies.
Diagnostic and Therapeutic Potential of Tetanus Toxin-Derivatives in Neurological Diseases.
Differences in the multiple step process of inhibition of neurotransmitter release induced by tetanus toxin and botulinum neurotoxins type A and B at Aplysia synapses.
Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments.
Different effects of botulinum A toxin and tetanus toxin on the transmitter releasing process at the mammalian neuromuscular junction.
Different frequencies of memory B-cells induced by tetanus, botulinum, and heat-labile toxin binding domains.
Different neuropathological effects of intrahippocampal injections of kainic acid and tetanus toxin.
Different response of the knockout mice lacking b-series gangliosides against botulinum and tetanus toxins.
Different VAMP/synaptobrevin complexes for spontaneous and evoked transmitter release at the crayfish neuromuscular junction.
Differential and time-dependent changes in gene expression for type II calcium/calmodulin-dependent protein kinase, 67 kDa glutamic acid decarboxylase, and glutamate receptor subunits in tetanus toxin-induced focal epilepsy.
Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides.
Differential effects of dopamine D1-like and D2-like receptor agonists on water drinking behaviour under thirsty conditions in mice with reduced dopamine secretion.
Differential effects of superantigen-induced "anergy" on priming and effector stages of a T cell-dependent antibody response.
Differential effects of tetanus toxin on inhibitory and excitatory neurotransmitter release from mammalian spinal cord cells in culture.
Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin.
Differential effects of various secretagogues on quantal transmitter release from mouse motor nerve terminals treated with botulinum A and tetanus toxin.
Differential neurochemical effects of chronic exposure of cerebral cortical cell culture to valproic acid, diazepam, or ethosuximide.
Differential potencies of effector genes in adult Drosophila.
Differential regulation of acetylcholine sensitivity and alpha-bungarotoxin-binding sites on ciliary ganglion neurons in cell culture.
Differential toxicity of chronic exposure to phenytoin, phenobarbital, or carbamazepine in cerebral cortical cell cultures.
Differentiation of PC12 cells with v-src: comparison with nerve growth factor.
Differentiation-regulated loss of the polysialylated embryonic form and expression of the different polypeptides of the neural cell adhesion molecule by cultured oligodendrocytes and myelin.
Diminished activity of protein kinase C in tetanus toxin-treated macrophages and in the spinal cord of mice manifesting generalized tetanus intoxication.
Direct evidence for the specific fixation of Cl. botulinum A neurotoxin to brain matter.
Direct modulation of the secretory machinery underlies PKA-dependent synaptic facilitation in hippocampal neurons.
Direct-Pathway Spiny Projection Neuron Inhibition Evokes Transient Circuit Imbalance Manifested as Rotational Behavior.
Discrimination between binding to CNS, toxicity and immunreactivity of derivatives of tetanus toxin.
Discrimination of human CD4 T cell clones based on their reactivity with antigen-presenting T cells.
Display of heterologous antigens on the Bacillus subtilis spore coat using CotC as a fusion partner.
Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans.
Dissociation of tetanus neurotoxin into two polypeptide fragments.
Distinct dopaminergic control of the direct and indirect pathways in reward-based and avoidance learning behaviors.
Distinct effects of clostridial toxins on activity-dependent modulation of autaptic responses in cultured hippocampal neurons.
Distinct functions of neuronal synaptobrevin in developing and mature fly photoreceptors.
Distinct kinetic changes in neurotransmitter release after SNARE protein cleavage.
Distinct protease requirements for antigen presentation in vitro and in vivo.
Distinct roles for Peyer's patch B cells for induction of antigen-specific IgA antibody responses in mice administered oral recombinant Salmonella.
Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behavior.
Distinct sites of action of clostridial neurotoxins revealed by double-poisoning of mouse motor nerve terminals.
Distinct targets for tetanus and botulinum A neurotoxins within the signal transducing pathway in chromaffin cells.
Distribution of tetanus toxin in rat peripheral nerve trunks during the development of local tetanus.
Disulfide formation in reduced tetanus toxin by thioredoxin: the pharmacological role of interchain covalent and noncovalent bonds.
Disulfide linkage between C3b and tetanus toxin on tetanus toxin-specific EBV-transformed B cells.
DNA and Adenoviral Vectors Encoding Carcinoembryonic Antigen Fused to Immunoenhancing Sequences Augment Antigen-Specific Immune Response and Confer Tumor Protection.
DNA and adenoviral vectors encoding carcinoembryonic antigen fused to immunoenhancing sequences augment antigen-specific immune response and confer tumor protection.
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire.
DNA fusion gene vaccines against cancer: from the laboratory to the clinic.
DNA fusion gene vaccines induce cytotoxic T-cell attack on naturally processed peptides of human prostate-specific membrane antigen.
DNA fusion vaccine designed to induce cytotoxic T cell responses against defined peptide motifs: implications for cancer vaccines.
DNA fusion vaccine designs to induce tumor-lytic CD8+ T-cell attack via the immunodominant cysteine-containing epitope of NY-ESO 1.
DNA fusion vaccines against B-cell tumors.
DNA fusion vaccines enter the clinic.
DNA fusion vaccines induce epitope-specific cytotoxic CD8(+) T cells against human leukemia-associated minor histocompatibility antigens.
DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8(+) T-cell responses and increases PSA doubling time.
DNA vaccination against multiple myeloma.
DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance.
DNA Vaccination with Electroporation Induces Increased Antibody Responses in Patients with Prostate Cancer.
DNA vaccines against cancer: from genes to therapy.
DNA vaccines against lymphoma: promotion of anti-idiotypic antibody responses induced by single chain Fv genes by fusion to tetanus toxin fragment C.
DNA vaccines to target the cancer testis antigen PASD1 in human multiple myeloma.
DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma.
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in the rat.
Does tetanus toxin have a sequence homology with the haemagglutinin of influenza virus?
Dominant role of betagamma subunits of G-proteins in oxytocin-evoked burst firing.
Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy.
Dopamine D2 Receptor as a Cellular Component Controlling Nocturnal Hyperactivities in Drosophila melanogaster.
DOPS Adjuvant Confers Enhanced Protection against Malaria for VLP-TRAP Based Vaccines.
Double anchorage to the membrane and intact interchain disulfide bond are required for the low pH induced entry of Tetanus and Botulinum Neurotoxins into neurons.
Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer's Disease Like Tau Aggregation.
DR alpha beta dimers released from complexes with invariant chain fail to stimulate alloreactive T cell clones.
Dual antigenic recognition by cloned human gamma delta T cells.
Dual properties of cultured retinoblastoma cells: immunohistochemical characterization of neuronal and glial markers.
Dynamical properties of LFPs from mice with unilateral injection of TeNT.
Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission.
Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor.
Early dendrite development in spinal cord cell cultures: a quantitative study.
Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25.
Early local tetanus: does tetanus toxin change the stimulus evoked discharge in afferents from the injected muscle?
Early segregation of a neuronal precursor cell line in the neural crest as revealed by culture in a chemically defined medium.
Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster.
Effect of 2,5-hexanedione and 3,4-dimethyl-2,5-hexanedione on retrograde axonal transport in sciatic nerve.
Effect of cortisone and desoxycorticosterone on infection with tetanus spores and upon the toxicity of tetanus toxin.
Effect of experimental limbic epilepsy on the estrus cycle and reproductive success in rats.
Effect of fragmentation of tetanus immune globulin (human) on neutralization of tetanus toxin.
Effect of medium composition on the production of tetanus toxin by Clostridium tetani.
Effect of seizures on hippocampal peptidergic neurons.
Effect of tetanus toxin in the goldfish.
Effect of tetanus toxin on basal and evoked release of 5-hydroxytryptamine and dopamine in rat hippocampus in vivo.
Effect of tetanus toxin on jaw reflexes.
Effect of tetanus toxin on oxytocin and vasopressin release from nerve endings of the neurohypophysis.
Effect of tetanus toxin on presynaptic inhibition in the spinal cord.
Effect of tetanus toxin on the accumulation of the permeant lipophilic cation tetraphenylphosphonium by guinea pig brain synaptosomes.
Effect of tetanus toxin on the content of glycine, gamma-aminobutyric acid, glutamate, glutamine and aspartate in the rat spinal cord.
Effect of tetanus toxin on the excitatory and the inhibitory post-synaptic potentials in the cat motoneurone.
Effect of tetanus toxin on the inhibitory neuromuscular junction of crayfish muscle.
Effect of tetanus toxin on the monosynaptic reflex.
Effect of tetanus toxin on transmitter release from substantia nigra and striatum in vitro.
Effect of tetanus toxin on uptake and potassium-evoked release of radio-labelled transmitters from the substantia nigra and striatum of the rat [proceedings]
Effect of the C-terminal domain of the heavy chain of tetanus toxin on dyskinesia caused by levodopa in 6-hydroxydopamine-lesioned rats.
Effective levels of tetanus toxin can be made in a production medium totally lacking both animal (e.g., brain heart infusion) and dairy proteins or digests (e.g., casein hydrolysates).
Effectiveness of Fragment C Domain of Tetanus Toxin and Pramipexole in an Animal Model of Parkinson's Disease.
Effects of 'casoparan', a peptide isolated from casein hydrolysates with mastoparan-like properties.
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
Effects of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Gut Microbiota in a Rat Model of Depression.
Effects of cyclic nucleotides on tetanus toxin paralyzed rabbit sphincter pupillae muscles.
Effects of myotoxins on skeletal muscle fibers.
Effects of tetanus toxin after intracerebral microinjection are antagonized by drugs enhancing GABAergic transmission in adult fowls.
Effects of tetanus toxin on catecholamine release from intact and digitonin-permeabilized chromaffin cells.
Effects of tetanus toxin on functional inhibition after injection in separate cortical areas in rat.
Effects of tetanus toxin on spontaneous and evoked transmitter release at inhibitory and excitatory synapses in the rat SDCN neurons.
Effects of tetanus toxin, Salmonella typhimurium porin, and bacterial lipopolysaccharide on platelet aggregation.
Effects of transgenic expression of botulinum toxins in Drosophila.
Effects of transient oxygen-glucose deprivation on G-proteins and G-protein-coupled receptors in rat CA3 pyramidal cells in vitro.
Efficacy demonstration of tetanus vaccines by double antigen ELISA.
Efficacy of intravenous immunoglobulin preparations against viral and bacterial infections in mouse protection tests.
Efficacy of vitamin C in counteracting tetanus toxin toxicity.
Efficacy, heat stability and safety of intranasally administered Bacillus subtilis spore or vegetative cell vaccines expressing tetanus toxin fragment C.
Electrical excitability of motoneurones in early local tetanus.
Electromyographic investigations on the mode of action of tetanus toxin.
Electron microscopic evidence for a transsynaptic migration of tetanus toxin in spinal cord motoneurons: an autoradiographic and morphometric study.
Electrophysiological analysis of inhibitory synaptic mechanisms in the preoptic area of the rat.
Electroporation as a "prime/boost" strategy for naked DNA vaccination against a tumor antigen.
Electrospray mass spectrometry of NeuAc oligomers associated with the C fragment of the tetanus toxin.
Elevation of levels of IgE antibody to tetanus toxin in individuals vaccinated with diphtheria-pertussis-tetanus vaccine.
ELISA for the routine determination of antitoxic immunity to tetanus.
Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction.
Endocytosis and retrograde axonal traffic in motor neurons.
Endogenous amino acid release from cultured cerebellar neuronal cells: effect of tetanus toxin on glutamate release.
Engineering the microflora to vaccinate the mucosa: serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli.
Enhanced CNS uptake of systemically administered proteins through conjugation with tetanus C-fragment.
Enhanced expression of soluble recombinant tetanus neurotoxin Hc in Escherichia coli as a tetanus vaccine candidate.
Enhanced mucosal delivery of antigen with cell wall mutants of lactic acid bacteria.
Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2.
Enhancement of antibody responses in DNA vaccination using a vector encoding a universal T-helper cell epitope.
Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.
Enhancement of DNA vaccine potency against legumain.
Enrichment and detection of live antigen-specific CD4(+) and CD8(+) T cells based on cytokine secretion.
Ensilicated tetanus antigen retains immunogenicity: in vivo study and time-resolved SAXS characterization.
Entrapping of impermeant probes of different size into nonpermeabilized synaptosomes as a method to study presynaptic mechanisms.
Entry of a recombinant, full-length, atoxic tetanus neurotoxin into Neuro-2a cells.
Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity.
Enzymatic breakdown of tetanus toxin.
Enzymatic fragmentation of tetanus toxin. Identification and characterization of an atoxic, immunogenic fragment.
Enzymatic hydrolysis of tetanus toxin by intrinsic and extrinsic proteases. Characterization of the fragments by monoclonal antibodies.
Epileptic activity outlasts disinhibition after intrahippocampal tetanus toxin in the rat.
Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy.
Epileptiform syndrome in rats produced by injecting tetanus toxin into the hippocampus.
Epitope Mapping of Tetanus Toxin by Monoclonal Antibodies: Implication for Immunotherapy and Vaccine Design.
Epitope repertoire of human CD4+ lines propagated with tetanus toxoid or with synthetic tetanus toxin sequences.
Epitope repertoire of human CD4+ T cells on tetanus toxin: identification of immunodominant sequence segments.
Epitope-directed processing of specific antigen by B lymphocytes.
Epitopes common to trypanosomes (T. cruzi, T. dionisii and T. vespertilionis (Schizotrypanum]: astrocytes and neurons.
Erratum to: Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments.
Escherichia coli-based production of a tumor idiotype antibody fragment - tetanus toxin fragment C fusion protein vaccine for B cell lymphoma.
Essential role of histidine peptides in tetanus toxin production.
Establishment of a monoclonal antibody recognizing an antigenic site common to Clostridium botulinum type B, C1, D, and E toxins and tetanus toxin.
Establishment of hybridomas secreting human monoclonal antibodies against tetanus toxin and hepatitis B virus surface antigen.
Estimating coupling direction between neuronal populations with permutation conditional mutual information.
Estrogen enhances depolarization-induced glutamate release through activation of phosphatidylinositol 3-kinase and mitogen-activated protein kinase in cultured hippocampal neurons.
Estrogen treatment enhances survival of cultured fetal rat amygdala neurons in a defined medium.
Evaluation of a guinea pig model to assess interference in the immunogenicity of different components of a combination vaccine comprising diphtheria, tetanus and acellular pertussis (DTaP) vaccine and haemophilus influenzae type b capsular polysaccharide conjugate vaccine.
Evaluation of a recombinant tetanus toxin subunit vaccine.
Evaluation of EBV transformation of human memory B-cells isolated by FACS and MACS techniques.
Evaluation of live-attenuated Salmonella vaccines expressing Campylobacter antigens for control of C. jejuni in poultry.
Evaluation of specific immune responses to BoNT/A and tetanus toxoid in patients undergoing treatment for neurologic disorders.
Evidence for a link between specific proteolysis and inhibition of [3H]-noradrenaline release by the light chain of tetanus toxin.
Evidence for a vesicle-mediated maintenance of store-operated calcium channels in a human embryonic kidney cell line.
Evidence for calcium-dependent vesicular transmitter release insensitive to tetanus toxin and botulinum toxin type F.
EVIDENCE FOR CENTRAL ANTISPASTIC EFFECT OF BOTULINUM TOXIN TYPE A.
Evidence for different exocytosis pathways in dendritic and terminal dopamine release in vivo.
Evidence for the functional role of monosialoganglioside GM1 in synaptic transmission in the rat hippocampus.
Evidence for the innervation of sperm storage tubules in the oviduct of the turkey (Meleagris gallopavo).
Evidence for the participation of nigrotectal gamma-aminobutyrate-containing neurones in striatal and nigral-derived circling in the rat.
Evidence of an exocytotic-like release of [3H]5-hydroxytryptamine induced by d-fenfluramine in rat hippocampal synaptosomes.
Evidence that transglutaminase and synapsin I are involved in the neuroparalytic action of tetanus toxin.
Evolution of triiodothyronine nuclear binding sites in hypothalamic serum-free cultures: evidence for their presence in neurons and astrocytes.
Ex vivo release of GABA from tetanus toxin-induced chronic epileptic foci decreased during the active seizure phase.
Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
Excitability and ion content of cerebral tissues treated with alkylating agents, tetanus toxin, or a neuraminidase.
Exocytosis in chromaffin cells: evidence for a MgATP-independent step that requires a pertussis toxin-sensitive GTP-binding protein.
Exocytotic and nonexocytotic modes of glutamate release from cultured cerebellar granule cells during chemical ischaemia.
Exogenous mRNA encoding tetanus or botulinum neurotoxins expressed in Aplysia neurons.
Experiences in the production of human monoclonal antibodies to tetanus toxoid.
Experimental models of chronic focal epilepsy: a critical review of four models.
Experimental studies on the interaction of tetanus toxin and toxoid.
Experiments in examination of the ;locked-jaw' induced by tetanus toxin.
Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals.
Expression and characterisation of the heavy chain of tetanus toxin: reconstitution of the fully-recombinant dichain protein in active form.
Expression and delivery of tetanus toxin fragment C fused to the N-terminal domain of SipB enhances specific immune responses in mice.
Expression and immunogenicity of an Echinococcus granulosus fatty acid-binding protein in live attenuated Salmonella vaccine strains.
Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908.
Expression and purification of a trivalent pertussis toxin-diphtheria toxin-tetanus toxin fusion protein in Escherichia coli.
Expression and Purification of Tetanus Toxin Fragment C in Escherichia coli BL21(DE3).
Expression of depolarizing voltage- and transmitter-activated currents in neuronal precursor cells from the rat brain is preceded by a proton-activated sodium current.
Expression of differentiation markers by chick embryo neuroretinal cells in vivo and in culture.
Expression of disulphide-bridge-dependent conformational epitopes and immunogenicity of the carboxy-terminal 19 kDa domain of Plasmodium yoelii merozoite surface protein-1 in live attenuated Salmonella vaccine strains.
Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain.
Expression of HLA-DP0401 molecules for identification of DP0401 restricted antigen specific T cells.
Expression of mRNAs encoding flip isoforms of GluR1 and GluR2 glutamate receptors is increased in rat hippocampus in epilepsy induced by tetanus toxin.
Expression of receptors for tetanus toxin and monoclonal antibody A2B5 by pancreatic islet cells.
Expression of SNARE proteins in enteroendocrine cell lines and functional role of tetanus toxin-sensitive proteins in cholecystokinin release.
Expression of synaptobrevin II, cellubrevin and syntaxin but not SNAP-25 in cultured astrocytes.
Expression of tetanus toxin fragment C in E. coli: high level expression by removing rare codons.
Expression of tetanus toxin Fragment C in tobacco chloroplasts.
Expression of tetanus toxin fragment C in yeast: gene synthesis is required to eliminate fortuitous polyadenylation sites in AT-rich DNA.
Expression of tetanus toxin fragment C.
Expression of tetanus toxin subfragments in vitro and characterization of epitopes.
Expression of Thy-1, H-2, and NS-4 cell surface antigens and tetanus toxin receptors in early postnatal and adult mouse cerebellum.
Expression of VAMP-2-like protein in kidney collecting duct intracellular vesicles. Colocalization with Aquaporin-2 water channels.
Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line.
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.
Extracts from neuron-enriched cultures of chick telencephalon stimulate the proliferation of rat oligodendrocytes.
Facilitatory effect of glutamate exocytosis from rat cerebrocortical nerve terminals by alpha-tocopherol, a major vitamin E component.
Factors affecting the immunogenicity of tetanus toxin fragment C expressed in Lactococcus lactis.
Factors Affecting the Production of Tetanus Toxin: Temperature.
Factors affecting the production of tetanus toxin; temperature.
Factors Influencing the Production of Tetanus Toxin: Gaseous Products of Growth.
Factors influencing the production of tetanus toxin; gaseous products of growth.
Failure of analysis of amino acid composition as a probe for sequence similarity in tetanus toxin.
Fast changes in the functional status of release sites during short-term plasticity: involvement of a frequency-dependent bypass of Rac at Aplysia synapses.
Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens.
Fate of labeled tetanus toxin in animal body.
Fate of tetanus toxin bound to the surface of primary neurons in culture: evidence for rapid internalization.
Fed-batch production of tetanus toxin by Clostridium tetani.
Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension.
Filopodia, lamellipodia and retractions at mouse neuromuscular junctions.
Fine tuning neuronal targeting of nanoparticles by adjusting the ligand grafting density and combining PEG spacers of different length.
First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427).
Fixation and locomotor activity are impaired by inducing tetanus toxin expression in adult Drosophila brain.
FIXATION OF TETANUS TOXIN BY SUBCELLULAR FRACTIONS OF BRAIN.
Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons.
Flow cytometric analysis of tetanus toxin binding to neuroblastoma cells.
Fluorescence emission and polarization analyses for evaluating binding of ruthenium metalloglycoclusters to lectins and tetanus toxin C-fragment.
Fluorescence emission and polarization for analyzing binding of ruthenium metalloglycocluster to lectin and tetanus toxin C-fragment.
Fluorescence imaging of fast retrograde axonal transport in living animals.
Force during stretches of rat skeletal muscles after hypertonia at short and long lengths.
Force-velocity relationship of tetanus toxin treated skeletal muscle.
Forebrain ischaemia with CA1 cell loss impairs epileptogenesis in the tetanus toxin limbic seizure model.
Formation and action of a peptidase which hydrolyzes histidine peptides required in tetanus toxin synthesis.
Formation of tetanus toxin within the bacterial cell.
Fragile X Mental Retardation Protein Requirements in Activity-Dependent Critical Period Neural Circuit Refinement.
Fragment A-B of tetanus toxin does not block neuromuscular transmission in the goldfish.
Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice.
Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy.
Fragment C of tetanus toxin: new insights into its neuronal signaling pathway.
Fragment C tetanus toxin: a putative activity-dependent neuroanatomical tracer.
Functional alterations of cat abducens neurons after peripheral tetanus neurotoxin injection.
Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles.
Functional characterisation of tetanus and botulinum neurotoxins binding domains.
Functional characterization of the catalytic site of the tetanus toxin light chain using permeabilized adrenal chromaffin cells.
Functional dissection of the serological DR LYGUE and genotypic DRB1*1303 specificities using a tetanus toxin-specific T-cell clone.
Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons.
Functional importance of synaptobrevin and SNAP-25 during exocytosis of histamine by rat gastric enterochromaffin-like cells.
Functional inactivation of dorsal medial striatum alters behavioral flexibility and recognition process in mice.
Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells.
Functional Oxygen Sensitivity of Astrocytes.
Functional studies in 3T3L1 cells support a role for SNARE proteins in insulin stimulation of GLUT4 translocation.
Functions of retrograde axonal transport.
Further evidence for the presence of subepithelial nerve cells in the rat ileum--an immunohistochemical study.
Further studies on the sympathomimetic action of tetanus toxin.
Fusion complex formation protects synaptobrevin against proteolysis by tetanus toxin light chain.
Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons.
Fusion protein vesicle-associated membrane protein 2 is implicated in IFN-gamma-induced piecemeal degranulation in human eosinophils from atopic individuals.
G-protein gamma subunit 1 is required for sugar reception in Drosophila.
GABAA receptors modulate early spontaneous excitatory activity in differentiating P19 neurons.
GABAergic cells and signals appear together in the early post-mitotic period of telencephalic and striatal development.
GAL4/UAS-WGA system as a powerful tool for tracing Drosophila transsynaptic neural pathways.
Gamma activity of the rigid cat caused by tetanus toxin.
Gamma interferon-induced specific binding of tetanus toxin on the GG2EE macrophage cell line.
Gamma-bias of the muscle poisoned by tetanus toxin.
Ganglioside GD3 enhances adherence of botulinum and tetanus neurotoxins to bovine brain synapsin I.
Ganglioside-induced adherence of botulinum and tetanus neurotoxins to adducin.
Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in mice.
Gangliosides as high affinity receptors for tetanus neurotoxin.
Gangliosides in nervous tissue cultures and binding of 125I-labelled tetanus toxin, a neuronal marker.
Gangliosides in phospholipid bilayer membranes: interaction with tetanus toxin.
Gangliosides mediate association of tetanus toxin with neural cells in culture.
Gangliosides mediate inhibitory effects of tetanus and botulinum A neurotoxins on exocytosis in chromaffin cells.
Gangliosides of cultured astroglia.
Gangliosides, the thyrotropin receptor, and autoimmune thyroid disease.
Gastrointestinal absorption of tetanus toxin in the fetal and newborn rat and rabbit.
Gene activation using FLP recombinase in C. elegans.
Gene transfer in the nervous system and implications for transsynaptic neuronal tracing.
Generalization of courtship learning in Drosophila is mediated by cis-vaccenyl acetate.
Generalized Tetanus in a Gyrfalcon ( Falco rusticolus ) with Pododermatitis.
Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response.
Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
Genetic characterisation of the botulinum toxin complex of Clostridium botulinum strain NCTC 2916.
Genetic detoxification of an aroA Salmonella enterica serovar Typhimurium vaccine strain does not compromise protection against virulent Salmonella and enhances the immune responses towards a protective malarial antigen.
Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish.
Genetic dissection of the circuit for hand dexterity in primates.
Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival in a mouse model of lymphoma.
Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration.
Germination-independent induction of cellular immune response by Bacillus subtilis spores displaying the C fragment of the tetanus toxin.
Glial cells in the pineal gland of mice and rats. A combined immunofluorescence and electron-microscopic study.
Glial Synaptobrevin mediates peripheral nerve insulation, neural metabolic supply, and is required for motor function.
Gliosis in the Mice Hippocampus Without Neuronal Death After Systemic Administration of High Dosage of Tetanus Toxin.
Glucocorticoids increase the endocytic activity of human dendritic cells.
Glucose tolerance during experimental tetanus toxicity in rabbits.
GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A in muscle cells.
Glutamate exocytosis from cerebellar granule cells: the mechanism of a transition to an L-type Ca2+ channel coupling.
Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine.
Glutamate transmission is involved in the mechanisms of neuronal degeneration produced by intrahippocampal tetanus toxin in rats.
Glutamate-induced exocytosis of glutamate from astrocytes.
Glutamine in the production of tetanus toxin.
GM1 binding-deficient exotoxin is a potent noninflammatory broad spectrum intradermal immunoadjuvant.
GT1b ganglioside prevents tetanus toxin-induced protein kinase C activation and down-regulation in the neonatal brain in vivo.
Haemagglutination antibody titre levels which give certain protection against tetanus toxin.
HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction.
Heat shock increases antigenic peptide generation but decreases antigen presentation.
Heiner Niemann as I remember him. "The end of tetanus toxin, the beginning of SNAREs, 1985-1993".
HER-2 DNA and protein vaccines containing potent Th cell epitopes induce distinct protective and therapeutic antitumor responses in HER-2 transgenic mice.
Heterogeneity of 125I-labeled tetanus toxin in isoelectric focusing on polyacrylamide gel and polyacrylamide gel electrophoresis.
Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia.
Heterologous expression of the cuticular-glutathione peroxidase of lymphatic filariae in an attenuated vaccine strain of Salmonella typhimurium abrogates H-2 restriction of specific antibody responses.
High affinity binding of tetanus toxin to mammalian brain membranes.
High level heterologous expression in E. coli using mutant forms of the lac promoter.
High level heterologous expression in E. coli using the anaerobically-activated nirB promoter.
High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein.
High vulnerability of dentate granule cells to the neuropathological effects induced by intrahippocampal injection of tetanus toxin.
High-level Expression of Tetanus Toxin Fragment C in Escherichia coli.
High-level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene.
High-level expression of tetanus toxin fragment C-thioredoxin fusion protein in Escherichia coli.
Highly immunogenic and protective recombinant vaccine candidate expressed in transgenic plants.
Hippocampal damage produced by tetanus toxin in rats can be prevented by lesioning CA1 pyramidal cell excitatory afferents.
HISTOLOGICAL CHANGES IN STRUCTURAL CONSTITUENTS OF SPINAL MOTONEURONS AFTER PICROTOXIN, STRYCHNINE AND TETANUS TOXIN ADMINISTRATION.
Histological identification of premotor neurons for horizontal saccades in monkey and man by parvalbumin immunostaining.
Historical links between toxinology and immunology.
History, extensive characterization and challenge of anti-tetanus serum from World War I: exciting remnants and deceived hopes : Centenarian IgGs lost their neutralization capacity.
HIV protein, transactivator of transcription, alters circadian rhythms through the light entrainment pathway.
HIV-1 transmission and function of virus-infected monocytes/macrophages.
How botulinum and tetanus neurotoxins block neurotransmitter release.
How does tetanus toxin act?
HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses.
Human CD14+ leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4.
Human dendritic cells are superior to B cells at presenting a major histocompatibility complex class II-restricted heterologous antigen expressed on recombinant Streptococcus gordonii.
Human dendritic cells very efficiently present a heterologous antigen expressed on the surface of recombinant gram-positive bacteria to CD4+ T lymphocytes.
Human lethal dose of tetanus toxin.
Human lymphoblastoid cell line producing protective monoclonal IgG1, kappa anti-tetanus toxin.
Human monoclonal antibodies with a protective activity against tetanus toxin.
Human monoclonal ScFv that inhibits cellular entry and metalloprotease activity of tetanus neurotoxin.
Human peripheral blood monocyte-derived interleukin-10-induced semi-mature dendritic cells induce anergic CD4(+) and CD8(+) T cells via presentation of the internalized soluble antigen and cross-presentation of the phagocytosed necrotic cellular fragments.
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates.
Human sperm capacitation is necessary for SNARE assembly in neurotoxin-resistant complexes.
Human spinal cord neurons in dissociated monolayer cultures: morphological, biochemical, and electrophysiological properties.
Human T cell leukemia/lymphoma virus type I infection of a CD4+ proliferative/cytotoxic T cell clone progresses in at least two distinct phases based on changes in function and phenotype of the infected cells.
Human T-cell responses to botulinum neurotoxin Proliferative responses in vitro of lymphocytes from botulinum neurotoxin A-treated movement disorder patients.
Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B.
Human T-lymphotropic virus type 1 peptides in chimeric and multivalent constructs with promiscuous T-cell epitopes enhance immunogenicity and overcome genetic restriction.
Human T4+ T-lymphocyte clones specific for the B fragment of tetanus toxin.
Humoral and cell mediated immune responses to a pertussis containing vaccine in pregnant and nonpregnant women.
Humoral and cellular immune responses in mice immunized with recombinant Mycobacterium bovis Bacillus Calmette-Guérin producing a pertussis toxin-tetanus toxin hybrid protein.
Hybrid tetanus toxin C fragment-diphtheria toxin translocation domain allows specific gene transfer into PC12 cells.
Hyperbaric oxygen therapy in mice injected with tetanus toxin.
Hyperbaric oxygen treatment following injection of tetanus toxin in mice.
Hyperexcitability of cultured central nervous system neurons caused by tetanus toxin.
Hyperosmolarity reduces GLUT4 endocytosis and increases its exocytosis from a VAMP2-independent pool in l6 muscle cells.
Hyposmolality differentially and spatiotemporally modulates levels of glutamine synthetase and serine racemase in rat supraoptic nucleus.
Hyposmolarity evokes norepinephrine efflux from synaptosomes by a depolarization- and Ca2+ -dependent exocytotic mechanism.
Hypothesis: a motor neuron toxin produced by a clostridial species residing in gut causes ALS.
Identification and assembly of V genes as idiotype-specific DNA fusion vaccines in multiple myeloma.
Identification and characterization of an 18-kilodalton, VAMP-like protein in suspension-cultured carrot cells.
Identification and partial characterization of a low affinity metal-binding site in the light chain of tetanus toxin.
Identification of a binding site for ganglioside on the receptor binding domain of tetanus toxin.
Identification of a ganglioside recognition domain of tetanus toxin using a novel ganglioside photoaffinity ligand.
Identification of a non-coding RNA and its putative involvement in the regulation of tetanus toxin synthesis in Clostridium tetani.
Identification of a novel linear epitope in tetanus toxin recognized by a protective monoclonal antibody: Implications for vaccine design.
Identification of a Tetanus Toxin Specific Epitope in Single Amino Acid Resolution.
Identification of an ion channel-forming motif in the primary structure of tetanus and botulinum neurotoxins.
Identification of cell types in rat hippocampal slices maintained in organotypic cultures.
Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.
Identification of novel small molecule ligands that bind to tetanus toxin.
Identification of novel small molecules that bind to two different sites on the surface of tetanus toxin C fragment.
Identification of SNAREs involved in regulated exocytosis in the pancreatic acinar cell.
Identification of the Amino Acid Residues Rendering TI-VAMP Insensitive toward Botulinum Neurotoxin B.
Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.
Identification of the Serum Complex Which Induces Cerebellar Granule Cell In Vitro Differentiation and Resistance to Excitatory Amino Acids.
Identification of two promiscuous T cell epitopes from tetanus toxin.
Identifying the principal protective antigenic determinants of type A botulinum neurotoxin.
Identity of the tetanus toxin receptor in nervous tissue.
Idiotypic DNA vaccination for the treatment of multiple myeloma: safety and immunogenicity in a phase I clinical study.
IgA protease from Neisseria gonorrhoeae inhibits exocytosis in bovine chromaffin cells like tetanus toxin.
IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages.
IL-12 is both required and sufficient for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells.
Immediate allergy to tetanus toxoid vaccine: determination of immunoglobulin E and immunoglobulin G antibodies to allergenic proteins.
Immune response and reactions to various dose regimens for raising hyperimmune antisera in sheep.
Immune response in mice following immunization with DNA encoding fragment C of tetanus toxin.
Immune response of male baboons to testis-specific LDH-C(4).
Immune response to fused core protein of hepatitis C virus and truncated tetanus toxin peptides in mice.
Immune responses in calves immunised orally or subcutaneously with a live Salmonella typhimurium aro vaccine.
Immune status and booster effects of low doses of tetanus toxoid in Swedish medical personnel.
Immune System Modifications Induced in a Mouse Model of Chronic Exposure to (90)Sr.
Immunisation strategies against prion diseases: prime-boost immunisation with a PrP DNA vaccine containing foreign helper T-cell epitopes does not prevent mouse scrapie.
Immunity in HIV-1-infected adults with a previous state of moderate-severe immune-suppression and more than 500 CD4+ T cell after highly active antiretroviral therapy.
Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin.
Immunization of female cynomolgus macaques with a synthetic epitope of sperm-specific lactate dehydrogenase results in high antibody titers but does not reduce fertility.
Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli.
Immunization of mice with DNA encoding fragment C of tetanus toxin.
Immunization of mice with poliovirus replicons expressing the C-fragment of tetanus toxin protects against lethal challenge with tetanus toxin.
Immunization with a multiple antigen peptide containing defined B- and T-cell epitopes: production of bactericidal antibodies against group B Neisseria meningitidis.
Immunization with a peptide corresponding to chlamydial heat shock protein 60 increases the humoral immune response in C3H mice to a peptide representing variable domain 4 of the major outer membrane protein of Chlamydia trachomatis.
Immunization with recombinant Streptococcus gordonii expressing tetanus toxin fragment C confers protection from lethal challenge in mice.
Immuno-informatics based approaches to design a novel multi epitope-based vaccine for immune response reinforcement against Leptospirosis.
Immunochemical studies on tetanus neurotoxin [proceedings]
Immunochemistry of tetanus toxin. The nitration of tyrosyl residues in tetanus toxin.
Immunocytochemical localization of tetanus toxin to synapses of spinal cord.
Immunocytochemical study on cholera toxin binding sites by monoclonal anti-cholera toxin antibody in neuronal tissue culture.
Immunodeficiency in alpha-mannosidosis: a matched case-control study on immunoglobulins, complement factors, receptor density, phagocytosis and intracellular killing in leucocytes.
Immunofluorescence staining of cultured neurons: a comparative study using tetanus toxin and neurofilament antisera.
Immunogenicity and protection in small-animal models with controlled-release tetanus toxoid microparticles as a single-dose vaccine.
Immunogenicity and reactogenicity of a single dose of a diphtheria--tetanus--acellular pertussis component vaccine (DTaP) compared to a diphtheria--tetanus toxoid (Td) and a diphtheria toxoid vaccine (d) in adults.
Immunogenicity of a bovine herpes virus I peptide expressed in tandem copies in attenuated Salmonella.
Immunogenicity of a promiscuous T cell epitope peptide based conjugate vaccine against benzo[a]pyrene: redirecting antibodies to the hapten.
Immunogenicity of a Salmonella typhimurium aroA aroD vaccine expressing a nontoxic domain of Clostridium difficile toxin A.
Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human ?-synuclein: feasibility study.
Immunogenicity of multiple antigen peptides containing Plasmodium vivax CS epitopes in BALB/c mice.
Immunogenicity of Plasmodium falciparum circumsporozoite protein multiple antigen peptide vaccine formulated with different adjuvants.
Immunogenicity of synthetic peptide constructs based on PvMSP9E795-A808, a linear B-cell epitope of the P. vivax Merozoite Surface Protein-9.
Immunoglobulin E-suppressing and immunoglobulin G-enhancing tetanus toxoid prepared by conjugation with pullulan.
Immunoreactive insulin from mouse brain cells in culture and whole rat brain.
Immunoreactivity of a new generation of horse F(ab')2 preparations against European viper venoms and the tetanus toxin.
Immunotherapy with human monoclonal antibodies. Fragment A specificity of polyclonal and monoclonal antibodies is crucial for full protection against tetanus toxin.
Impact of plasmid stability on oral DNA delivery by Salmonella enterica serovar Typhimurium.
Impact of prior immunological exposure on vaccine delivery by Salmonella enterica serovar Typhimurium.
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Improved Lentiviral Transduction of ALS Motoneurons in vivo via Dual Targeting.
Improved Survival of HER2+ Breast Cancer Patients Treated with Trastuzumab and Chemotherapy Is Associated with Host Antibody Immunity against the HER2 Intracellular Domain.
In search of the central respiratory neurons: I. Dissociated cell cultures of respiratory areas from the upper medulla.
In search of the central respiratory neurons: II. Electrophysiologic studies of medullary fetal cells inherently sensitive to CO2 and low pH.
In search of the real respiratory neurons: culture of medullary fetal cells sensitive to CO2 and low pH.
In silico analyses of heat shock protein 60 and calreticulin to designing a novel vaccine shifting immune response toward T helper 2 in atherosclerosis.
In silico analysis of transmembrane protein 31 (TMEM31) antigen to design novel multiepitope peptide and DNA cancer vaccines against melanoma.
In silico rational design of a novel tetra-epitope tetanus vaccine with complete population coverage using developed immunoinformatics and surface epitope mapping approaches.
In situ scanning probe microscopy studies of tetanus toxin-membrane interactions.
In vitro and in vivo stability of recombinant plasmids in a vaccine strain of Salmonella enterica var. Typhimurium.
In vitro CNS tissue analogues formed by self-organisation of reaggregated post-natal brain tissue.
In vitro determination of specific toxicity in tetanus vaccines.
In vitro determination of tetanus toxicity by an endopeptidase assay linked to a ganglioside-binding step.
In vitro effect of tetanus toxin on GABA release form rat hippocampal slices.
In vitro exocytosis in sea urchin eggs requires a synaptobrevin-related protein.
In vitro immunization for antibody production against tetanus toxin and toxoid. 3. Recombinant gamma interferon and indomethacin support specific antibody production induced by antigen-pulsed immobilized monocytes.
In vitro kinetics of allergen- and microbe-induced IL-4 and IFN-gamma mRNA expression in PBMC of pollen-allergic patients.
In vitro labeling strategies for identifying primary neural tissue and a neuronal cell line after transplantation in the CNS.
In vivo blockade of neural activity alters dendritic development of neonatal CA1 pyramidal cells.
In vivo characterization of the murine intranasal model for assessing the immunogenicity of attenuated Salmonella enterica serovar Typhi strains as live mucosal vaccines and as live vectors.
In vivo distribution of radioactivity in mice after injection of biodegradable polymer microspheres containing 14C-labeled tetanus toxoid.
In vivo evidence for an activity-independent maturation of AMPA/NMDA signaling in the developing hippocampus.
In vivo induction of type 1 and 2 immune responses against protein antigens.
In vivo neuronal tracing with GFP-TTC gene delivery.
In vivo persistence of expanded clones specific for bacterial antigens within the human T cell receptor alpha/beta CD4-8- subset.
In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters.
In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles.
In vivo translocation and down-regulation of protein kinase C following intraventricular administration of tetanus toxin.
Inactivated tetanus as an immunological smokescreen: A major step towards harnessing tetanus-based therapeutics.
Inactivation of botulinum and tetanus toxins by chelators.
Increase of permeability of synaptosomes and liposomes by the heavy chain of tetanus toxin.
Increased cyclooxygenase-2 and nuclear factor-?B/p65 expression in mouse hippocampi after systemic administration of tetanus toxin.
Increased expression of GAD mRNA during the chronic epileptic syndrome due to intrahippocampal tetanus toxin.
Increased presynaptic protein kinase C activity and glutamate release in rats with a prenatally induced hippocampal lesion.
Increased susceptibility to tetanus toxin-induced seizures in immature rats.
Increasing color density with decreasing toxicity of tetanus toxin in the Mueller medium.
Increasing the potency of neutralizing single-domain antibodies by functionalization with a CD11b/CD18 binding domain.
INCUBATION PERIOD AND THE INITIAL SYMPTOMS OF TETANUS: A CLINICAL ASSESSMENT OF THE PROBLEM OF THE PASSAGE OF TETANUS TOXIN TO THE CENTRAL NERVOUS SYSTEM.
Individual Neuronal Subtypes Exhibit Diversity in CNS Myelination Mediated by Synaptic Vesicle Release.
Inducible expression of retrograde transynaptic genetic tracer in mice.
Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.
Induction of pro-apoptotic antibodies to triple negative breast cancer by vaccination with TRAIL death receptor DR5 DNA.
Induction of protection against tetanus toxin in mice by tetanus toxoid-liposome conjugate.
Induction of protective antibodies in Saimiri monkeys by immunization with a multiple antigen construct (MAC) containing the Plasmodium vivax circumsporozoite protein repeat region and a universal T helper epitope of tetanus toxin.
Induction of protective CTL responses against the Plasmodium yoelii circumsporozoite protein by immunization with peptides.
Induction of protective immunity against Streptococcus mutans colonization after mucosal immunization with attenuated Salmonella enterica serovar typhimurium expressing an S. mutans adhesin under the control of in vivo-inducible nirB promoter.
Induction of protective polyclonal antibodies by immunization with a Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine.
Induction of spheroid cytoplasmic bodies in a rat muscle by local tetanus.
Induction of sustained and elevated immune responses to weakly immunogenic synthetic malarial peptides by encapsulation in biodegradable polymer microspheres.
Induction of T cell adhesion by antigen stimulation and modulation by the coreceptor CD4.
Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer.
Infected open depressed skull fracture complicated with tetanus grade I in an unimmunized child: a rare case report with literature review.
Influence of afferent synaptic innervation on the discharge variability of cat abducens motoneurones.
Influence of codon usage on the immunogenicity of a DNA vaccine against tetanus.
Influence of frequent infectious exposures on general and varicella-zoster virus-specific immune responses in pediatricians.
Influence of intracerebroventricular administration of tetanus toxin on experimental seizures and protection afforded by some antiepileptic drugs in mice.
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
Influence of preimmunization with tetanus toxoid on immune responses to tetanus toxin fragment C-guest antigen fusions in a Salmonella vaccine carrier.
Influence of the medium on the inactivation of tetanus toxin by X-ray irradiation.
Influence on the mouse immune system of chronic ingestion of (137)Cs.
Inhibition by clostridial neurotoxins of calcium-independent [3H]noradrenaline outflow from freeze-thawed synaptosomes: comparison with synaptobrevin hydrolysis.
Inhibition by tetanus and botulinum A toxin of the release of [3H]noradrenaline and [3H]GABA from rat brain homogenate.
Inhibition by tetanus toxin of sodium-dependent, high-affinity [3H]5-hydroxytryptamine uptake in rat synaptosomes.
Inhibition of a vaccine-induced anti-tumor B cell response by soluble protein antigen in the absence of continuing T cell help.
Inhibition of bacterial carbonic anhydrases and zinc proteases: from orphan targets to innovative new antibiotic drugs.
Inhibition of exocytosis in bovine adrenal medullary cells by botulinum toxin type D.
Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.
Inhibition of macrophage secretion by tetanus toxin is not directly linked to cytosolic calcium homeostasis.
Inhibition of neurotransmitter release by botulinum neurotoxins and tetanus toxin at Aplysia synapses: role of the constituent chains.
Inhibition of neurotransmitter release by synthetic proline-rich peptides shows that the N-terminal domain of vesicle-associated membrane protein/synaptobrevin is critical for neuro-exocytosis.
Inhibition of peptide binding to DR molecules by a leupeptin-induced invariant chain fragment.
Inhibition of SNARE-mediated membrane traffic impairs cell migration.
Inhibition of synaptosomal choline uptake by tetanus and botulinum A toxin. Partial dissociation of fixation and effect of tetanus toxin.
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels.
Inhibition of tetanus toxin fragment C binding to ganglioside G(T1b) by monoclonal antibodies recognizing different epitopes.
Inhibition of the immune response to whooping cough and tetanus vaccines by malaria infection, and the effect of pertussis adjuvant.
Inhibition of transmitter release correlates with the proteolytic activity of tetanus toxin and botulinus toxin A in individual cultured synapses of Hirudo medicinalis.
Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins.
Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors.
Injectable phenytoin loaded polymeric microspheres for the control of temporal lobe epilepsy in rats.
Injection of tetanus toxin into the neocortex elicits persistent epileptiform activity but only transient impairment of GABA release.
Insight into the potential for DNA idiotypic fusion vaccines designed for patients by analysing xenogeneic anti-idiotypic antibody responses.
Insights in metabolism and toxin production from the complete genome sequence of Clostridium tetani.
Insights into Clostridium tetani: From genome to bioreactors.
Insights into the different catalytic activities of Clostridium neurotoxins.
Insights into the Mechanisms by Which Clostridial Neurotoxins Discriminate between Gangliosides.
Insights into the tetanus toxin model of early-onset epilepsy from long-term video monitoring during anticonvulsant therapy.
Instruments for oral disease-intervention strategies: recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis.
Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP.
Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts.
Intact inhibition of the stretch reflex during general tetanus.
Intensive Care Management of Severe Tetanus.
Interaction between a Novel Oligopeptide Fragment of the Human Neurotrophin Receptor TrkB Ectodomain D5 and the C-Terminal Fragment of Tetanus Neurotoxin.
Interaction between tetanus toxin and rabbit kidney: a comparison with rat brain preparations.
Interaction of botulinum and tetanus toxins with the lipid bilayer surface.
Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides.
Interaction of Haemophilus influenzae type b conjugate vaccines with diphtheria-tetanus-pertussis vaccine in control tests.
Interaction of labelled tetanus toxin and toxoid with substructures of rat brain and spinal cord in vitro.
Interaction of labelled tetanus toxin with substructures of rat spinal cord in vivo.
Interaction of solid-phase gangliosides with tetanus toxin and toxoid.
Interaction of tetanus toxin and toxoid with cultured neuroblastoma cells. Analysis by immunofluorescence.
Interaction of tetanus toxin derived hybrid proteins with neuronal cells.
Interaction of tetanus toxin with lipid vesicles at low pH. Protection of specific polypeptides against proteolysis.
Interaction of tetanus toxin with lipid vesicles. Effects of pH, surface charge, and transmembrane potential on the kinetics of channel formation.
Interactions between synaptic vesicle fusion proteins explored by atomic force microscopy.
Interferon-alpha and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells.
Internalization and proteolytic action of botulinum toxins in CNS neurons and astrocytes.
Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments.
Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions.
Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons.
Intraaxonal and extraaxonal transport of 125I-tetanus toxin in early local tetanus.
Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells.
Intracellular Localization of Amyloid-? Peptide in SH-SY5Y Neuroblastoma Cells.
Intracellular pathway of Onconase that enables its delivery to the cytosol.
Intracellular targeting of CEA results in Th1-type antibody responses following intradermal genetic vaccination by a needle-free jet injection device.
Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells.
Intracerebral injections of kainic acid and tetanus toxin: possible models for the signs of chorea and dystonia.
Intrahippocampal tetanus toxin produces generalized convulsions and neurodegeneration in rats: antagonism by NMDA receptor blockers.
Intranasal immunisation against tetanus with an attenuated Bordetella bronchiseptica vector expressing FrgC: improved immunogenicity using a Bvg-regulated promoter to express FrgC.
Intranasal immunization with tetanus toxoid and CNF1 as a new mucosal adjuvant protects BALB/c mice against lethal challenge.
Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin.
Intraspinal distribution and reaction in the grey matter with tetanus toxin of intracisternally injected anti-tetanus toxoid F(ab')2 fragments.
Intrathecal Immunoglobulin for treatment of adult patients with tetanus: A randomized controlled 2x2 factorial trial.
Intratumoral DNA electroporation induces anti-tumor immunity and tumor regression.
Intravenous immunoglobulins induce the in vitro differentiation of human B lymphocytes and the secretion of IgG.
Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks.
Introduction of macromolecules into bovine adrenal medullary chromaffin cells and rat pheochromocytoma cells (PC12) by permeabilization with streptolysin O: inhibitory effect of tetanus toxin on catecholamine secretion.
Investigation of a pain syndrome of spinal origin (on the concept of the generator mechanism of the pain syndrome).
Investigation of ansB and sspA derived promoters for multi- and single-copy antigen expression in attenuated Salmonella enterica var. typhimurium.
Investigation of the detoxification mechanism of formaldehyde-treated tetanus toxin.
Investigation of the neuronal aggregate generating seizures in the rat tetanus toxin model of epilepsy.
Investigation of the tetanus toxin from two different strains of Clostridium tetani.
Involvement of basal protein kinase C and extracellular signal-regulated kinase 1/2 activities in constitutive internalization of AMPA receptors in cerebellar Purkinje cells.
Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4+ memory T cells.
Involvement of major histocompatibility complex class I antigens in T cell activation.
Involvement of the nerve growth factor-inducible large external glycoprotein (NILE) in neurite fasciculation in primary cultures of rat brain.
Involvement of the Zn-binding region of tetanus toxin in B and T recognition. Influence of Zn fixation.
Ionic channel current burst analysis by a machine learning based approach.
Irreplaceability of Neuronal Ensembles after Memory Allocation.
Is the test for irreversibility of tetanus toxoids still relevant?
Is there retrograde axonal transport of tetanus toxin in both alpha and beta fibres?
Isolated light chain of tetanus toxin inhibits exocytosis: studies in digitonin-permeabilized cells.
Isolated lymphoid follicles are not IgA inductive sites for recombinant Salmonella.
Isolation and characterization of a novel human monoclonal antibody that neutralizes tetanus toxin.
Isolation and characterization of CD6- T cells from peripheral blood.
Isolation and characterization of human antigen-specific B lymphocytes.
Isolation and purification by high performance liquid chromatography of a tetanus toxin fragment (fragment [A-B]) derived from mildly papain-treated toxin.
Isolation and purification of two antigenically active, "complimentary" polypeptide fragments of tetanus neurotoxin.
Isolation and some properties of nontoxigenic derivatives of a strain of Clostridium tetani.
Isolation, purification, and characterization of fragment B, the NH2-terminal half of the heavy chain of tetanus toxin.
Key protection factors against tetanus: Anti-tetanus toxin antibody affinity and its ability to prevent tetanus toxin - ganglioside interaction.
Kinetics of the mucosal antibody secreting cell response and evidence of specific lymphocyte migration to the lung after oral immunisation with attenuated S. enterica var. typhimurium.
L- and T-type calcium channels in cultured neuronal cell lines are insensitive to tetanus toxin.
Labelled wheat germ agglutinin and tetanus toxin as highly sensitive retrograde tracers in the CNS: the afferent fiber connections of the rat nucleus caudatus.
Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats.
Lack of proliferative response by gluten-specific T cells in the blood and gut of patients with dermatitis herpetiformis.
Lactobacilli as live vaccine delivery vectors: progress and prospects.
Lactococcus lactis: high-level expression of tetanus toxin fragment C and protection against lethal challenge.
Large scale production of tetanus toxin. III. The production of highly potent and pure tetanus toxin.
Large-scale prospective T cell function assays in shipped, unfrozen blood samples: experiences from the multicenter TRIGR trial.
Lateral mobility of presynaptic ?7-containing nicotinic receptors and its relevance for glutamate release.
Latex agglutination test for detection of tetanus antitoxins.
Leaky Lactococcus cultures that externalize enzymes and antigens independently of culture lysis and secretion and export pathways.
Lectins from Triticum vulgaris and Limax flavus are universal antagonists of botulinum neurotoxin and tetanus toxin.
Letter: Neural transport of tetanus toxin.
Levetiracetam inhibits oligomeric A?-induced glutamate release from human astrocytes.
Levetiracetam-loaded biodegradable polymer implants in the tetanus toxin model of temporal lobe epilepsy in rats.
Light and electron microscopic changes in slow and fast skeletal muscle fibres and their motor end-plates in the mouse after the local injection of tetanus toxin.
Light and peptidergic eclosion hormone neurons stimulate a rapid eclosion response that masks circadian emergence in Drosophila.
Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuro-neuronal synapses, and its internalization is mediated by heavy chain.
Limbic epilepsy induced by tetanus toxin: a longitudinal electroencephalographic study.
Limitations of in vivo IL-12 supplementation strategies to induce Th1 early life responses to model viral and bacterial vaccine antigens.
Limited proteolysis of single-chain tetanus toxin by tissue enzymes, in cultured brain tissue and during retrograde axonal to the spinal cord.
Limited proteolysis of tetanus toxin. Relation to activity and identification of cleavage sites.
Linkage of exogenous T-cell epitopes to the 19-kilodalton region of Plasmodium yoelii merozoite surface protein 1 (MSP1(19)) can enhance protective immunity against malaria and modulate the immunoglobulin subclass response to MSP1(19).
Linking genetically defined neurons to behavior through a broadly applicable silencing allele.
Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses.
Lipid interaction of Pseudomonas aeruginosa exotoxin A. Acid-triggered permeabilization and aggregation of lipid vesicles.
Lipid interaction of tetanus neurotoxin. A calorimetric and fluorescence spectroscopy study.
Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons.
Local and systemic neutralizing antibody responses induced by intranasal immunization with the nontoxic binding domain of toxin A from Clostridium difficile.
Local circuit abnormalities in chronically epileptic rats after intrahippocampal tetanus toxin injection in infancy.
Local tetanus after intradermal injection of tetanus toxin.
Local tetanus in cats: the influence of neuromuscular activity on spinal distribution of 125 I labelled tetanus toxin.
Local tetanus in rats; concentration of amino acids as studied in spinal cord segments, spinal roots, and dorsal root ganglia.
Localisation of the MRC OX-2 glycoprotein on the surfaces of neurones.
Localization of cardiac parasympathetic preganglionic neurons in the medulla oblongata of pigeon, Columba livia: a study using fragment C of tetanus toxin.
Localization of cellubrevin to the Golgi complex in pancreatic acinar cells.
Localization of putative receptors for tetanus toxin and botulinum neurotoxin type A in rat central nervous system.
Localized tetanus in immunized mice.
Locally applied valproate enhances survival in rats after neocortical treatment with tetanus toxin and cobalt chloride.
Locomotor control by the central complex in Drosophila-An analysis of the tay bridge mutant.
Long term stability of lyophilized plasmid DNA pDERMATT.
Long-peptide therapeutic vaccination against CRPV-induced papillomas in HLA-A2.1 transgenic rabbits.
Long-term changes in hippocampal physiology and learning ability of rats after intrahippocampal tetanus toxin.
Long-term culture of neurones from human cerebral cortex in serum-free medium.
Long-term seizure dynamics are determined by the nature of seizures and the mutual interactions between them.
Loss of hilar somatostatin neurons following tetanus toxin-induced seizures.
Low pH induces a hydrophobic domain in the tetanus toxin molecule.
Lymphocyte response to tetanus toxin T-cell epitopes: effects of tetanus vaccination and concurrent malaria prophylaxis.
Magnitude of alloresponses to MHC class I/II expressing human cardiac myocytes is limited by their intrinsic ability to process and present antigenic peptides.
Maintenance of HIV-Specific Memory B-Cell Responses in Elite Controllers Despite Low Viral Burdens.
Maintenance of immunocytologically identified Purkinje cells from mouse cerebellum in monolayer culture.
Mammalian neuronal differentiation: early expression of a neuronal phenotype from mouse neural crest cells in a chemically defined culture medium.
Management and prevention of tetanus.
MANAGEMENT OF MEDICAL COMPLICATIONS ASSOCIATED WITH A PRESUMED TETANUS INFECTION IN A NORTHWEST BORNEAN ORANGUTAN (PONGO PYGMAEUS PYGMAEUS).
Manipulation of pathogen-derived genes to influence antigen presentation via DNA vaccines.
Mapping the glycation sites in the neoglycoconjugate from hexasaccharide antigen of Vibrio cholerae, serotype Ogawa and the recombinant tetanus toxin C-fragment carrier.
Mapping the major human T helper epitopes of tetanus toxin. The emerging picture.
Mass spectrometry and non-covalent protein-ligand complexes: confirmation of binding sites and changes in tertiary structure.
Mastoparan stimulates GABA release from MIN6 cells: relationship between SNARE proteins and mastoparan action.
Measuring immunoglobulin g antibodies to tetanus toxin, diphtheria toxin, and pertussis toxin with single-antigen enzyme-linked immunosorbent assays and a bead-based multiplex assay.
Mechanism of action of tetanus and botulinum neurotoxins.
Mechanism of ethanol-induced insulin secretion from INS-1 and INS-1E tumor cell lines.
Mechanism of tetanus toxin in neuronal cell death.
Mechanism of the local tetanus induced by intramuscular tetanus toxin.
MECHANISM OF THE REACTION BETWEEN BILE SALTS AND BLOOD SERUM AND THE EFFECT OF CONJUGATION IN THE FORMATION OF BILE SALTS.
Mechanisms of Antigen Adsorption Onto an Aluminum-Hydroxide Adjuvant Evaluated by High-Throughput Screening.
Mechanisms of the release of anterogradely transported neurotrophin-3 from axon terminals.
Mechanisms through which ammonia regulates cortical collecting duct net proton secretion.
Mechanisms underlying LTP of inhibitory synaptic transmission in the deep cerebellar nuclei.
Mechanisms underlying oxytocin-induced excitation of supraoptic neurons: prostaglandin mediation of actin polymerization.
Mechanosensitive currents in putative aortic baroreceptor neurons in vitro.
Medullary actions of tetanus toxin. An electrophysiological study in man.
Menstrum for culture preservation and medium for seed preparation in a tetanus toxin production process containing no animal or dairy products.
Mesial temporal lobe epilepsy: pathogenesis, induced rodent models and lesions.
Metal substitution of tetanus neurotoxin.
Metallopeptidase inhibitors of tetanus toxin: A combinatorial approach.
MHC class II expression by microglia in tetanus toxin-induced experimental epilepsy in the rat.
MHC class II-associated invariant chain peptide replacement by T cell epitopes: engineered invariant chain as a vehicle for directed and enhanced MHC class II antigen processing and presentation.
Microbiologic characterization and antimicrobial susceptibility of Clostridium tetani isolated from wounds of patients with clinically diagnosed tetanus.
Microelectrophoretic effects of (+/-) cis-1,3-aminocyclohexane carboxylic acid on nigral neurones in control and tetanus toxin treated rats [proceedings]
Micrometer-sized supported lipid bilayer arrays for bacterial toxin binding studies through total internal reflection fluorescence microscopy.
Microtubules and microfilaments participate in the inhibition of synaptosomal noradrenaline release by tetanus toxin.
Mimicking the humoral immune response in vitro results in antigen-specific isotype switching supported by specific autologous T helper cells: generation of human HIV-1-neutralizing IgG monoclonal antibodies from naive donors.
Miniature excitatory synaptic currents in cultured hippocampal neurons.
Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A.
Minimum essential factors required for vesicle mobilization at hippocampal synapses.
Mode of action of tetanus toxin on the neuromuscular junction.
Mode of action of tetanus toxin.
Mode of enlargement of young mouse neuromuscular junctions observed repeatedly in vivo with visualization of pre- and postsynaptic borders.
Modification of tetanus toxin with selective chemical reagents.
Modification of the ELISA for the estimation of tetanus antitoxin in human sera.
Modulation by epitope-specific antibodies of class II MHC-restricted presentation of the tetanus toxin antigen.
Modulation of antigen processing and presentation by covalently linked complement C3b fragment.
Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants.
Modulation of ion gradients and glutamate release in cultured cerebellar granule cells by ouabain.
Modulation of locomotor behaviors by location-specific epileptic spiking and seizures.
Modulation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex by P2Y receptor activation.
Modulation of sensory neuron mechanotransduction by PKC- and nerve growth factor-dependent pathways.
Molecular aspects of tetanus and botulinum neurotoxin poisoning.
Molecular basis for tetanus toxin coreceptor interactions.
Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence.
Molecular Methods for Identification of Clostridium tetani by Targeting Neurotoxin.
Molecular pharmacology of botulinum toxin and tetanus toxin.
Molecular structure of tetanus neurotoxin as revealed by Fourier transform infrared and circular dichroic spectroscopy.
Monoclonal antibodies against tetanus toxin and toxoid.
Monoclonal antibodies as probes of tetanus toxin structure and function.
Monoclonal antibody (M2) to glial and neuronal cell surfaces.
More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines.
More than at the Neuromuscular Synapse: Actions of Botulinum Neurotoxin A in the Central Nervous System.
Mosquito inoculation: an alternative bioassay for toxins.
Motoneuron uptake from the circulation of the binding fragment of tetanus toxin.
Motor neuron targeting of IGF-1 attenuates age-related external Ca2+-dependent skeletal muscle contraction in senescent mice.
Motor neurone targeting of IGF-1 prevents specific force decline in ageing mouse muscle.
Movement of labeled macromolecules to the goldfish optic tectum following intraocular injection of 125I-labelled tetanus toxin.
Mucosal and cellular immune responses elicited by recombinant Lactococcus lactis strains expressing tetanus toxin fragment C.
Mucosal delivery of antigens using adsorption to bacterial spores.
Mucosal delivery of murine interleukin-2 (IL-2) and IL-6 by recombinant strains of Lactococcus lactis coexpressing antigen and cytokine.
Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum.
Mucosally delivered Salmonella live vector vaccines elicit potent immune responses against a foreign antigen in neonatal mice born to naive and immune mothers.
Multi-epitope insert modulates solubility-based and chromatographic purification of human papilloma virus 16 L1-based vaccine without inhibiting virus-like particle assembly.
Multifunctional receptor-targeted nanocomplexes for magnetic resonance imaging and transfection of tumours.
Multimeric bivalent immunogens from recombinant tetanus toxin H(C) fragment, synthetic hexasaccharides, and a glycopeptide adjuvant.
Multiple and diverse forms of regulated exocytosis in wild-type and defective PC12 cells.
Multiple domains of tetanus toxin direct entry into primary neurons.
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.
Multiplexed measurement of serum antibodies using an array biosensor.
Multireactive human monoclonal antibodies.
Muscle extractives in the production of tetanus toxin.
Mushroom bodies suppress locomotor activity in Drosophila melanogaster.
Mutant molecular motors disrupt neural circuits in Drosophila.
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants.
Mutation in slowmo causes defects in Drosophila larval locomotor behaviour.
Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis.
Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons.
Myostatin DNA vaccine increases skeletal muscle mass and endurance in mice.
Na+-channel-associated scorpion toxin receptor sites as probes for neuronal evolution in vivo and in vitro.
NADPH oxidase 4-derived superoxide mediates flow-stimulated NKCC2 activity in thick ascending limbs.
Nano-sized Soluplus® polymeric micelles enhance the induction of tetanus toxin neutralising antibody response following transcutaneous immunisation with tetanus toxoid.
Nasal immunization with attenuated Salmonella Typhimurium expressing an MrpA-TetC fusion protein significantly reduced Proteus mirabilis colonization in the mouse urinary tract.
Natural processing sites for human cathepsin E and cathepsin D in tetanus toxin: implications for T cell epitope generation.
Naturally acquired antibodies to tetanus toxin in humans and animals from the galápagos islands.
Naturally acquired immunity to tetanus toxin in an isolated community.
Neocortical slices from adult chronic epileptic rats exhibit discharges of higher voltages and broader spread.
Neonatal tetanus despite protective serum antitoxin concentration.
Nephrotoxic effects of tetanus toxin: an ultrastructural study.
Neural differentiation, NCAM-mediated adhesion, and gap junctional communication in neuroectoderm. A study in vitro.
Neural induction and in vitro initial expression of neurofilament and tetanus toxin binding site molecules in amphibians.
Neural induction: embryonic determination elicits full expression of specific neuronal traits.
Neuroimmunology. II: Antigenic specificity of the nervous system.
Neuromuscular blocking in acutely tetanus intoxicated mice.
Neuron generation in dissociated cell cultures from fetal rat cerebral cortex.
Neuron-specific delivery of nucleic acids mediated by Tet1-modified poly(ethylenimine).
Neuronal acquisition of tetanus toxin binding sites: relationship with the last mitotic cycle.
Neuronal activity and the establishment of normal and epileptic circuits during brain development.
Neuronal activity-dependent membrane traffic at the neuromuscular junction.
Neuronal and glial cells in the superficial layers of early postnatal mouse neocortex: immunofluorescence observations.
Neuronal binding of tetanus toxin compared to its ganglioside binding fragment (H(c)).
Neuronal development and migration in explant cultures of the adult canary forebrain.
Neuronal differentiation of cloned human teratoma cells in response to retinoic acid in vitro.
Neuronal influence on antigenic marker profile, cell shape and proliferation of cultured astrocytes obtained by microdissection of distinct layers from the early postnatal mouse cerebellum.
Neuronal lysosomal enzyme replacement using fragment C of tetanus toxin.
Neuronal properties of monkey adrenal medulla in vitro.
Neuronal sensitivity to tetanus toxin requires gangliosides.
Neuronal survival during electrical blockade is increased by 8-bromo cyclic adenosine 3',5' monophosphate.
Neuronal targeting of cardiotrophin-1 by coupling with tetanus toxin C fragment.
Neuropathology of the chronic epileptic syndrome induced by intrahippocampal tetanus toxin in rat: preservation of pyramidal cells and incidence of dark cells.
Neuropharmacological characterization of fragment B from tetanus toxin.
Neurophysiological aspects of tetanus toxin effects on the motor system.
Neuropil pattern formation and regulation of cell adhesion molecules in Drosophila optic lobe development depend on synaptobrevin.
Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy.
Neuroprotective effects of C-terminal domain of tetanus toxin on rat brain against motorneuron damages after experimental spinal cord injury.
Neuroprotective efficiency of tetanus toxin C fragment in model of global cerebral ischemia in Mongolian gerbils.
Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model.
Neurotoxicity of nitroxyl: insights into HNO and NO biochemical imbalance.
Neurotoxins as probes in the study of neuronal development.
Neurotransmission selectively regulates synapse formation in parallel circuits in vivo.
Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease.
Neutralization of MERS coronavirus through a scalable nanoparticle vaccine.
Neutralization of tetanus toxin by a novel chimeric monoclonal antibody.
Neutralization of tetanus toxin by distinct monoclonal antibodies binding to multiple epitopes on the toxin molecule.
Neutralization of tetanus toxin by human and rabbit immunoglobulin classes and subunits.
Neutralization of tetanus toxin by human monoclonal antibodies directed against tetanus toxin fragment C.
Neutralizing antibodies and immunoprotection against pertussis and tetanus obtained by use of a recombinant pertussis toxin-tetanus toxin fusion protein.
New combination vaccines: DTaP-IPV (Kinrix) and DTaP-IPV/Hib (Pentacel).
New concepts on tetanus immunization: naturally acquired immunity.
New strategies for vaccination and imunomodulation in NHL.
Nicotine induces dendritic spine remodeling in cultured hippocampal neurons.
Nitrogen-gas bubbling during the cultivation of Clostridium tetani produces a higher yield of tetanus toxin for the preparation of its toxoid.
Nociceptive signals induce trafficking of TRPA1 to the plasma membrane.
Non-cell autonomous influence of the astrocyte system xc- on hypoglycaemic neuronal cell death.
Non-invasive, epicutaneous immunisation with toxoid in deformable vesicles protects mice against tetanus, chiefly owing to a Th2 response.
Non-viral gene delivery of the GDNF, either alone or fused to the C-fragment of tetanus toxin protein, prolongs survival in a mouse ALS model.
Non-viral neuronal gene delivery mediated by the HC fragment of tetanus toxin.
Nonclassical Antigen-Presenting Cells Stimulate the Proliferation of Th0 but not Th1/Th2 Clones and Modulate the Cytokine Pattern of T-Helper Clones.
Nontoxic Shiga toxin derivatives from Escherichia coli possess adjuvant activity for the augmentation of antigen-specific immune responses via dendritic cell activation.
Nonvesicular release of acetylcholine is required for axon targeting in the Drosophila visual system.
Noradrenaline release from permeabilized synaptosomes is inhibited by the light chain of tetanus toxin.
Norepinephrine exocytosis stimulated by alpha-latrotoxin requires both external and stored Ca2+ and is mediated by latrophilin, G proteins and phospholipase C.
Novel actin-like filament structure from Clostridium tetani.
Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase.
Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
Novel neutralizing human monoclonal antibodies against tetanus neurotoxin.
Novel use of anaerobically induced promoter, dmsA, for controlled expression of fragment C of tetanus toxin in live attenuated Salmonella enterica serovar Typhi strain CVD 908-htrA.
Nucleotide sequence of the gene coding for Clostridium botulinum (Clostridium argentinense) type G neurotoxin: genealogical comparison with other clostridial neurotoxins.
Nucleus Accumbens Dopamine D1-Receptor-Expressing Neurons Control the Acquisition of Sign-Tracking to Conditioned Cues in Mice.
Observations on the passage of tetanus toxin through the placenta and fetal membranes of the rat.
OH. treatment of tetanus toxin reduces its susceptibility to limited proteolysis with more efficient presentation to specific T cells.
Olfactory neural circuitry for attraction to amino acids revealed by transposon-mediated gene trap approach in zebrafish.
On the antigens participating in the third zone of flocculation of crude tetanus toxin.
On the enzymatic activity of tetanus toxin.
On the mode of release of tetanus toxin from the bacterial cell.
On the Occurrence of Toxic Compounds of Tetanus Toxin and Antitoxin, Tetanus Toxin and Brain Emulsions.
On the role of polysialoglycosphingolipids as tetanus toxin receptors. A study with lipid monolayers.
On the role of voltage-dependent calcium channels in calcium signaling of astrocytes in situ.
On the structure of tetanus toxin.
On-chip native gel electrophoresis-based immunoassays for tetanus antibody and toxin.
Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach.
Optimization of tetanus toxoid ammonium sulfate precipitation process using response surface methodology.
Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy.
Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses.
Oral immunization with attenuated Salmonella enterica serovar Typhimurium encoding Cryptosporidium parvum Cp23 and Cp40 antigens induces a specific immune response in mice.
Oral immunogenicity of tomato-derived sDPT polypeptide containing Corynebacterium diphtheriae, Bordetella pertussis and Clostridium tetani exotoxin epitopes.
Oral priming of mice by recombinant spores of Bacillus subtilis.
Oral vaccination against tetanus: comparison of the immunogenicities of Salmonella strains expressing fragment C from the nirB and htrA promoters.
Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier.
Oral vaccination of mice against tetanus with recombinant Lactococcus lactis.
Oral vaccine models: multiple delivery systems employing tetanus toxoid.
Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani.
Oviduct contraction in Drosophila is modulated by a neural network that is both, octopaminergic and glutamatergic.
Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin.
Oxytocin Rapidly Changes Astrocytic GFAP Plasticity by Differentially Modulating the Expressions of pERK 1/2 and Protein Kinase A.
Papain-derived fragment IIc of tetanus toxin: its binding to isolated synaptic membranes and retrograde axonal transport.
Partial protection against Plasmodium vivax blood-stage infection in Saimiri monkeys by immunization with a recombinant C-terminal fragment of merozoite surface protein 1 in block copolymer adjuvant.
Partial Raphe Dysfunction in Neurotransmission Is Sufficient to Increase Mortality after Anoxic Exposures in Mice at a Critical Period in Postnatal Development.
Participation of peptides in tetanus toxin production.
Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required for Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference.
Parvalbumin-containing GABA cells and schizophrenia: experimental model based on targeted gene delivery through adeno-associated viruses.
Parvalbumin-positive interneurons of the prefrontal cortex support working memory and cognitive flexibility.
Pathogenesis of local tetanus in rats: neural ascent of tetanus toxin.
Pathway-specific control of reward learning and its flexibility via selective dopamine receptors in the nucleus accumbens.
Pathway-specific modulation of nucleus accumbens in reward and aversive behavior via selective transmitter receptors.
Pediatric diphtheria and tetanus toxoids-adsorbed vaccine: immune response to the first booster following the diphtheria and tetanus toxoids vaccine primary series.
Pelvic nerve grafts restore bladder function in denervated rats.
Pentavalent replicon vaccines against botulinum neurotoxins and tetanus toxin using DNA-based Semliki Forest virus replicon vectors.
Peptide-antibody conjugates for tumour therapy: a MHC-class-II-restricted tetanus toxin peptide coupled to an anti-Ig light chain antibody can induce cytotoxic lysis of a human B-cell lymphoma by specific CD4 T cells.
Peptide-induced T cell clones: specificity, MHC restriction, proliferation and cytokine pattern as a function of different stimulations.
Perceptive bilateral deafness following clinical tetanus to a neonate.
Periodate-modified gangliosides enhance surface binding of tetanus toxin to PC12 pheochromocytoma cells.
Peripheral Administration of Tetanus Toxin Hc Fragment Prevents MPP
Permanent tetraplegia as a consequence of tetanus neonatorum. Evidence for widespread lower motor neuron damage.
Peroxynitrite and nitric oxide donors induce neuronal apoptosis by eliciting autocrine excitotoxicity.
Peyer's patches are required for intestinal immunoglobulin A responses to Salmonella spp.
Phage display of a human antibody against Clostridium tetani toxin.
Phagocytosis, germination and killing of Bacillus subtilis spores presenting heterologous antigens in human macrophages.
Pharmacological experiments on the binding and internalization of the 50,000 dalton carboxyterminus of tetanus toxin at the cholinergic neuromuscular junction.
Pharmacological management of tetanus: an evidence-based review.
Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara.
Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases.
Photopolymerized cross-linked polyacrylamide gels for on-chip protein sizing.
Physical effects of tetanus toxin on model membranes containing ganglioside.
Physicochemical and immunochemical assays for monitoring consistent production of tetanus toxoid.
Physiological and behavioural consequences of seizures induced in the rat by intrahippocampal tetanus toxin.
Physiological release of endogenous tau is stimulated by neuronal activity.
Pig kidney legumain: an asparaginyl endopeptidase with restricted specificity.
PKCgamma-induced trafficking of AMPA receptors in embryonic zebrafish depends on NSF and PICK1.
Plant viral genes in DNA idiotypic vaccines activate linked CD4+ T-cell mediated immunity against B-cell malignancies.
Plasminogen activator secretion by granule neurons in cultures of developing cerebellum.
Plasticity of developing cerebellar cells in vitro studied with antibodies against the NG2 antigen.
Plasticity of presynaptic and postsynaptic elements of neuromuscular junctions repeatedly observed in living adult mice.
Pluronic F127-based systemic vaccine delivery systems.
Pneumatic hydrodynamics influence transplastomic protein yields and biological responses during in vitro shoot regeneration of Nicotiana tabacum callus: Implications for bioprocess routes to plant-made biopharmaceuticals.
Pneumococcal conjugate vaccine followed by pneumococcal polysaccharide vaccine; immunogenicity in patients with ataxia-telangiectasia.
Pneumococcal Surface Protein A does not affect the immune responses to a combined diphtheria tetanus and pertussis vaccine in mice.
Pore formation by tetanus toxin, its chain and fragments in neuronal membranes and evaluation of the underlying motifs in the structure of the toxin molecule.
Possible role of sialocompounds in the uptake of choline into synaptosomes and nerve cell cultures.
Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice.
Postischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet451 reduces cerebral infarction following focal ischemia/reperfusion in rats.
Postoperative tetanus after laparoscopic obturator hernia repair for strangulated ileus: report of a case.
Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila.
Postsynaptic VAMP/Synaptobrevin Facilitates Differential Vesicle Trafficking of GluA1 and GluA2 AMPA Receptor Subunits.
Potassium-evoked glutamate release liberates arachidonic acid from cortical neurons.
Potent CD4+ T-cell epitope P30 enhances HER2/neu-engineered dendritic cell-induced immunity against Tg1-1 breast cancer in transgenic FVBneuN mice by enhanced CD4+ T-cell-stimulated CTL responses.
Pre-clinical efficacy and characterization of candidate vaccines for treatment of opioid use disorders using clinically viable carrier proteins.
Pre-emptive treatment for Clostridium tetani: importance of early recognition and treatment in the community.
Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7.
Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7.
Predicting differential antigen-antibody contact regions based on solvent accessibility.
Predicting the stimulation effectiveness using pre-stimulation neural states via optogenetic activation of the medial septum glutamatergic neurons modulating the hippocampal neural activity.
Preferential Targeting of Lateral Entorhinal Inputs onto Newly Integrated Granule Cells.
Preliminary histochemical and electron microscopic observations on the nervous system of hydra.
Premotor neurons for vertical eye movements in the rostral mesencephalon of monkey and human: histologic identification by parvalbumin immunostaining.
Prenatal and postnatal ontogenesis of neurotransmitter-synthetizing enzymes and [125I]tetanus toxin binding capacity in the mouse hypothalamus.
Preparation of affinity-purified, biotinylated tetanus toxin, and characterization and localization of cell surface binding sites on nerve growth factor-treated PC12 cells.
Preparation of conjugates using two tetanus toxin derived fragments: their binding to gangliosides and isolated synaptic membranes and their immunological properties.
Preparation of MUC-1 oligomers using an improved convergent solid-phase peptide synthesis.
Presence of a novel epithelial antigen on rat cerebellar cell lines as detected by a monoclonal antibody.
Presentation of T-cell epitopes assembled as multiple-antigen peptides to murine and human T lymphocytes.
Presynaptic calcium channels and field-evoked transmitter exocytosis from cultured cerebellar granule cells.
Presynaptic dysregulation of the paraventricular thalamic nucleus causes depression-like behavior.
Presynaptic effect of tetanus toxin at the neuromuscular junction.
Presynaptic exocytosis regulates NR2A mRNA expression in cultured neocortical neurones.
Presynaptic inhibition of the monosynaptic reflex during local tetanus in the cat.
Presynaptic or postsynaptic origin of acetylcholinesterase at neuromuscular junctions? An immunological study in heterologous nerve-muscle cultures.
Pretectal projections to the oculomotor complex of the monkey and their role in eye movements.
Prevention by the NMDA receptor antagonist, MK801 of neuronal loss produced by tetanus toxin in the rat hippocampus.
Prevention of myonecrosis in mdx mice: effect of immobilization by the local tetanus method.
Prime-boost with alternating DNA vaccines designed to engage different antigen presentation pathways generates high frequencies of peptide-specific CD8+ T cells.
Primed vesicles can be distinguished from docked vesicles by analyzing their mobility.
Prior immunity to homologous and heterologous Salmonella serotypes suppresses local and systemic anti-fragment C antibody responses and protection from tetanus toxin in mice immunized with Salmonella strains expressing fragment C.
Proceedings: Structure-function relationship of tetanus toxin: studies on "complementary" polypeptide fragments of the toxin.
Proceedings: The action of tetanus toxin on the electrical activity of the rabbit's brain.
Proceedings: The effect of lanthanum on miniature junction potentials at the goldfish neuromuscular jucntion after block by tetanus toxin.
Processing and presentation of tetanus toxin by antigen-presenting cells from patients with chronic granulomatous disease (CGD) to human specific T cell clones are not impaired.
Processing of tetanus and botulinum A neurotoxins in isolated chromaffin cells.
Processing of tetanus toxin by human antigen-presenting cells. Evidence for donor and epitope-specific processing pathways.
Production and characterization of monoclonal antibodies to tetanus toxin.
Production and characterization of recombinant light chain and carboxyterminal heavy chain fragments of tetanus toxin.
Production of a novel multi-epitope peptide vaccine for cancer immunotherapy in TC-1 tumor-bearing mice.
Production of biologically active light chain of tetanus toxin in Escherichia coli. Evidence for the importance of the C-terminal 16 amino acids for full biological activity.
Production of neutralizing human monoclonal antibody directed to tetanus toxin in CHO cell.
Production of Recombinant Human scFv Against Tetanus Toxin Heavy Chain by Phage Display Technology.
PRODUCTION OF TETANUS TOXIN ON PEPTONE-FREE MEDIA.
Production, characterization and applications of a tetanus toxin specific monoclonal antibody T-62.
Progenitor cells from embryonic chick dorsal root ganglia differentiate in vitro to neurons: biochemical and electrophysiological evidence.
Promiscuous T cell epitopes boosts specific IgM immune response against a P0 peptide antigen from sea lice in different teleost species.
Properties and use of botulinum toxin and other microbial neurotoxins in medicine.
Properties of Ca(2+)-dependent exocytosis in cultured astrocytes.
Properties of neurons from dissociated fetal rat brain in serum-free culture.
Properties of purified tetanus toxin and toxoid.
Prostigmine inhibits neutralization of tetanus toxin by brain homogenates.
Protection against experimental melioidosis following immunisation with a lipopolysaccharide-protein conjugate.
Protection against Experimental Melioidosis with a Synthetic manno-Heptopyranose Hexasaccharide Glycoconjugate.
Protection against malaria by Plasmodium yoelii sporozoite surface protein 2 linear peptide induction of CD4+ T cell- and IFN-gamma-dependent elimination of infected hepatocytes.
Protection against Staphylococcus aureus and tetanus infections by a combined vaccine containing SasA and TeNT?Hc in mice.
Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines.
Protection against tetanus toxin after intragastric administration of two recombinant lactic acid bacteria: impact of strain viability and in vivo persistence.
Protection against tetanus toxin in mice nasally immunized with recombinant Lactococcus lactis expressing tetanus toxin fragment C.
Protection against tetanus toxin using a plant-based vaccine.
Protection of mice against tetanus toxin by combination of two human monoclonal antibodies recognizing distinct epitopes on the toxin molecule.
Protection of mice with polyvinylpyrrolidone against lethal doses of tetanus toxin.
Protection test and early antibody response to tetanus immunization.
Protective antigen-mediated antibody response against a heterologous protein produced in vivo by Bacillus anthracis.
Protective effect of supplemental superoxide dismutase on survival of neuronal cells during starvation. Requirement for cytosolic distribution.
Protective human hybridoma antibody to tetanus toxin.
Protective mucosal immunity in aging is associated with functional CD4+ T cells in nasopharyngeal-associated lymphoreticular tissue.
Protective murine monoclonal antibodies to tetanus toxin.
Protein biotoxins of military significance.
Protein kinase C and clostridial neurotoxins affect discrete and related steps in the secretory pathway.
Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4.
Proteolysis of SNAP-25 by types E and A botulinal neurotoxins.
Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage.
Proteolysis of synthetic peptides by type A botulinum neurotoxin.
Proteolytic cleavage of cellubrevin and vesicle-associated membrane protein (VAMP) by tetanus toxin does not impair insulin-stimulated glucose transport or GLUT4 translocation in rat adipocytes.
Proteolytic cleavage of tetanus toxin increases activity.
Proteolytic fragmentation of tetanus toxin by subcellular fractions of JY, a B lymphoblastoid cell line.
Proteomics integrated with Escherichia coli vector-based vaccines and antigen microarrays reveals the immunogenicity of a surface sialidase-like protein of Propionibacterium acnes.
Pseudorabies virus as a transneuronal tract tracing tool: specificity and applications to the sympathetic nervous system.
Purification and some properties of tetanolysin.
Purification of bacterial exotoxins. The case of botulinum, tetanus, anthrax, pertussis and cholera toxins.
Purification of High Titer Tetanus Toxin.
Purification of tetanus toxin and its major peptides.
Purification of tetanus toxin and its peptide components by preparative polyacrylamide gel electrophoresis.
Purification of tetanus toxin and toxoid by ion exchange chromatography.
Purification of tetanus toxin by multi-membrane electrodecantation.
Purification of tetanus toxin with the aid of Sephadex gels.
Purification of tetanus toxin.
Quantification of tetanus antitoxin in human sera. I. Counter-immunoelectrophoresis.
Quantifying epileptogenesis in rats with spontaneous and responsive brain state dynamics.
Quantitation of commercial equine tetanus antitoxin by competitive enzyme-linked immunosorbent assay.
Quantitative analysis of bacterial toxin affinity and specificity for glycolipid receptors by surface plasmon resonance.
Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography.
Quantitative characterization of the ultrastructural changes in axo-dendritic synapses induced by tetanus toxin.
Quantitative comparison between tetanus toxin, some fragments and toxoid for binding and axonal transport in the rat.
Quantitative distribution of tetanus toxin in peripheral nerves and central nervous system.
Quantitative immunoassays for type II collagen and its cyanogen bromide peptides.
Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes.
Quaternary structure of botulinum and tetanus neurotoxins as probed by chemical cross-linking and native gel electrophoresis.
Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway.
Randomized clinical trial of DTaP5-HB-IPV-Hib vaccine administered concomitantly with meningococcal serogroup C conjugate vaccines during the primary infant series.
Rapid behavioural and biochemical effects of tetanus toxin microinjected into the substantia nigra: a dual role for GABA?
Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy.
Rapid induction of autoantibodies against Nogo-A and MOG in the absence of an encephalitogenic T cell response: implication for immunotherapeutic approaches in neurological diseases.
Rapid, sensitive, and specific detection of Clostridium tetani by loop-mediated isothermal amplification assay.
Rapid, simplified method for production and purification of tetanus toxin.
Rat basophilic leukemia cells express syntaxin-3 and VAMP-7 in granule membranes.
Rat kidney papilla contains abundant synaptobrevin protein that participates in the fusion of antidiuretic hormone-regulated water channel-containing endosomes in vitro.
Rat nerve cell cultures in pharmacology and toxicology.
Rat neural antigen-2 (RAN-2): a cell surface antigen on astrocytes, ependymal cells, Müller cells and lepto-meninges defined by a monoclonal antibody.
Reassessing the role of HLA-DRB3 T-cell responses: Evidence for significant expression and complementary antigen presentation.
Recall antigen activation induces prompt release of CCR5 ligands from PBMC: implication in memory responses and immunization.
Recent Advances in Design of Immunogenic and Effective Naked DNA Vaccines against Cancer.
Reciprocal age-dependent pattern of two neuronal markers, tetanus toxin and neuron-specific enolase, in postnatal rat sensory and sympathetic neurons.
Recognition of higher order patterns in proteins: immunologic kernels.
Recombinant and truncated tetanus neurotoxin light chain: cloning, expression, purification, and proteolytic activity.
Recombinant baculovirus expressing the FrC-OVA protein induces protective antitumor immunity in an EG7-OVA mouse model.
Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways.
Recombinant fusion peptides containing single or multiple repeats of a ubiquitous T-helper epitope are highly immunogenic.
Recombinant GDNF: tetanus toxin fragment C fusion protein produced from insect cells.
Recombinant GST-I-A beta 28-induced efficient serum antibody against A beta 42.
Recombinant Lactobacillus johnsonii as a mucosal vaccine delivery vehicle.
Recombinant Salmonella enterica serovar Typhi in a prime-boost strategy.
Recombinant Subunit Rotavirus Trivalent Vaccine Candidate: Physicochemical Comparisons and Stability Evaluations of Three Protein Antigens.
Recombinant vaccines against infectious hematopoietic necrosis virus: production by the Caulobacter crescentus S-layer protein secretion system and evaluation in laboratory trials.
Reconstitution of depolarization and Ca2+-evoked secretion in Xenopus oocytes monitored by membrane capacitance.
Reconstitution of tetanus neurotoxin from two antigenically active polypeptide fragments.
Reconstruction of a pathway of antigen processing and class II MHC peptide capture.
Recovery from 6 weeks of repeated strain injury to rat soleus muscles.
Recruitment of renal dopamine 1 receptors requires an intact microtubulin network.
Recruitment order of cat abducens motoneurons and internuclear neurons.
Recurrent seizures and the molecular maturation of hippocampal and neocortical glutamatergic synapses.
Recycling of the membrane-anchored chemokine, CX3CL1.
Reduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: evidence for an exocytotic mechanism.
Reduction of epileptiform activity through local valproate-implants in a rat neocortical epilepsy model.
Reduction of the ganglioside binding activity of the tetanus toxin HC fragment destroys immunogenicity: implications for development of novel tetanus vaccines.
Reductive chain separation of botulinum A toxin--a prerequisite to its inhibitory action on exocytosis in chromaffin cells.
Reductive cleavage of tetanus toxin and botulinum neurotoxin A by the thioredoxin system from brain. Evidence for two redox isomers of tetanus toxin.
Reevaluation of the role of gangliosides as receptors for tetanus toxin.
Refinement of ectopic protein expression through the GAL4/UAS system in Bombyx mori: application to behavioral and developmental studies.
Refining GAL4-driven transgene expression in Drosophila with a GAL80 enhancer-trap.
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke.
Regions recognized on the light chain of botulinum neurotoxin type A by T lymphocytes of SJL and BALB/c mice primed with inactivated toxin.
Regulated delivery of AMPA receptor subunits to the presynaptic membrane.
Regulated exocytosis: a novel, widely expressed system.
Regulation of kinetic and pharmacological properties of synaptic NMDA receptors depends on presynaptic exocytosis in rat hippocampal neurones.
Regulation of myelin structure and conduction velocity by perinodal astrocytes.
Regulation of synaptic connectivity: levels of Fasciclin II influence synaptic growth in the Drosophila CNS.
Regulation of toxin synthesis in Clostridium botulinum and Clostridium tetani.
Relation of spastic and flaccid paralysis to retrograde transport of 125I-tetanus toxin and its 125I-Ibc fragment. Modulating effect of F (ab) antibodies directed to specific areas on the toxin molecule.
Relations between the effect of tetanus toxin on the neuromuscular transmission and histological functional properties of various muscles of the rat.
Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation.
Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca(2+) -dependent P2Y1 receptor mechanism.
Release of ATP induced by hypertonic solutions in Xenopus oocytes.
Release of D,L-threo-beta-hydroxyaspartate as a false transmitter from excitatory amino acid-releasing nerve terminals.
Release of dopamine from human neocortex nerve terminals evoked by different stimuli involving extra- and intraterminal calcium.
Release of DR molecules from complexes with invariant chain through the formation of a C-terminal 25 kDa invariant chain fragment.
Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity.
Removal of neuroblastoma cells from bone marrow by a direct monoclonal antibody rosetting technique.
Renewal of EBV-hybridoma method: efficient generation of recombinant fully human neutralizing IgG antibodies specific for tetanus toxin by use of tetroma cells.
Repeated amphetamine couples norepinephrine transporter and calcium channel activities in PC12 cells.
Replacement of the in vivo neutralisation test for efficacy demonstration of tetanus vaccines ad us. vet.
Requirement of at least two distinct monoclonal antibodies for efficient neutralization of tetanus toxin in vivo.
Residual enzymatic activity of the tetanus toxin light chain present in tetanus toxoid batches used for vaccine production.
Resistance induced by concanavalin A and phytohaemagglutinin P against tetanus toxin in mice.
Resolving the Molecular Steps in Clostridial Neurotoxin Light Chain Translocation.
Response of Human T Cells to Tetanus Neurotoxin HCC Sub-Domain: T Cell Cytokine Production and Activation Marker Induced by HCC.
Restoration of exocytosis occurs after inactivation of intracellular tetanus toxin.
Restriction of secretory granule motion near the plasma membrane of chromaffin cells.
Results of an international transferability study of the BINACLE (binding and cleavage) assay for in vitro detection of tetanus toxicity.
Retargeted clostridial neurotoxins as novel agents for treating chronic diseases.
Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin.
Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro.
Retinoic acid-induced neural differentiation of embryonal carcinoma cells.
Retrograde axonal and transsynaptic transport of macromolecules: physiological and pathophysiological importance.
Retrograde axonal transport of an exogenous enzyme covalently linked to B-IIb fragment of tetanus toxin.
Retrograde axonal transport of specific macromolecules as a tool for characterizing nerve terminal membranes.
Retrograde trans-synaptic transfer of green fluorescent protein allows the genetic mapping of neuronal circuits in transgenic mice.
Retrograde transneuronal transfer of the C-fragment of tetanus toxin.
Retrograde transneuronal transport properties of fragment C of tetanus toxin.
Retrograde transport of tetanus toxin through a chain of two neurons.
Retrograde, trans-synaptic and transneuronal transport of fragment C of tetanus toxin by sympathetic preganglionic neurons.
Reverse mode Na(+)/Ca(2+) exchangers trigger the release of Ca(2+) from intracellular Ca(2+) stores in cultured rat embryonic cortical neurons.
Reversible deafferentation of abducens motoneurons and internuclear neurons with tetanus neurotoxin.
Reversible effects of low doses of tetanus toxin on synaptic inhibition in the substantia nigra and turning behaviour in the rat.
Reversible effects of tetanus toxin on striatal-evoked responses and [3H]-gamma-aminobutyric acid release in the rat substantia nigra.
Reversible suppression of glutamatergic neurotransmission of cerebellar granule cells in vivo by genetically manipulated expression of tetanus neurotoxin light chain.
Review of the role of inhibitory neurons in chronic epileptic foci induced by intracerebral tetanus toxin.
Rhythmic activity in the cerebellum and spinal cord of rabbits receiving tetanus toxin intravenously.
Rhythmic cerebellar and cortical electric activity in tetanus intoxicated rabbits.
Role for astroglial ?1-adrenoreceptors in gliotransmission and control of synaptic plasticity in the neocortex.
Role of AMPA receptor trafficking in NMDA receptor-dependent synaptic plasticity in the rat lateral amygdala.
Role of gangliosides in the uptake and retrograde axonal transport of cholera and tetanus toxin as compared to nerve growth factor and wheat germ agglutinin.
Role of granule-cell transmission in memory trace of cerebellum-dependent optokinetic motor learning.
Role of membrane gangliosides in the binding and action of bacterial toxins.
Role of PKA signaling in D2 receptor-expressing neurons in the core of the nucleus accumbens in aversive learning.
Role of protein kinase C in short-term transmission at the mammalian neuromuscular junction.
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth.
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein in membrane domains transport and homeostasis.
Role of the Axis Cylinder in Transport of Tetanus Toxin.
Role of transglutaminase in [3H]5-HT release from synaptosomes and in the inhibitory effect of tetanus toxin.
Role of vesicle-associated membrane protein-2, through Q-soluble N-ethylmaleimide-sensitive factor attachment protein receptor/R-soluble N-ethylmaleimide-sensitive factor attachment protein receptor interaction, in the exocytosis of specific and tertiary granules of human neutrophils.
Rotatory effects of intracerebral tetanus toxin injections.
Route of transport of tetanus toxin to the CNS: fluorescence microscopy in experimental tetanus.
Ruthenium red interferes with the tetanus toxin inhibition of potassium-stimulated GABA release from rat cerebral cortex slices.
S100A10-Mediated Translocation of Annexin-A2 to SNARE Proteins in Adrenergic Chromaffin Cells Undergoing Exocytosis.
Safety and immune responses to attenuated Salmonella enterica serovar typhi oral live vector vaccines expressing tetanus toxin fragment C.
Safety and immunogenicity of a parenterally administered rotavirus VP8 subunit vaccine in healthy adults.
Safety and Immunogenicity of a Recombinant Tetanus Vaccine in Healthy Adults in China: A Randomized, Double-Blind, Dose Escalation, Placebo- and Positive-Controlled, Phase 1/2 Trial.
Salmonella enterica serovar typhimurium surA mutants are attenuated and effective live oral vaccines.
Salmonella typhimurium as a basis for a live oral Echinococcus granulosus vaccine.
Salmonella vaccines for use in humans: present and future perspectives.
Salmonella-mediated mucosal cell-mediated immunity.
Scanning for T helper epitopes with human PBMC using pools of short synthetic peptides.
scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor.
scFv6.C4 DNA vaccine with fragment C of tetanus toxin increases protective immunity against CEA-expressing tumor.
Secretion from bovine chromaffin cells acutely expressing exogenous proteins using a recombinant Semliki Forest virus containing an EGFP reporter.
Seizure entrainment with polarizing low-frequency electric fields in a chronic animal epilepsy model.
Selective binding, uptake, and retrograde transport of tetanus toxin by nerve terminals in the rat iris. An electron microscope study using colloidal gold as a tracer.
Selective depression of synaptic transmission by tetanus toxin: a comparative study on hippocampal and neostriatal slices.
Selective inhibition of cytokine-induced lysozyme activity by tetanus toxin in the GG2EE macrophage cell line.
Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.
Selective regulation of the perinuclear distribution of glucose transporter 4 (GLUT4) by insulin signals in muscle cells.
Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport.
Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice.
Selective trans-synaptic migration of tetanus toxin after retrograde axonal transport in peripheral sympathetic nerves: a comparison with nerve growth factor.
Selective uptake and retrograde axonal transport of dopamine-beta-hydroxylase antibodies in peripheral adrenergic neurons.
Selective uptake of C-fragment of tetanus toxin by sympathetic preganglionic nerve terminals.
Selective uptake of tritiated glycine, GABA and D-aspartate by retinal cells in culture: a study using autoradiography and simultaneous immunofluorescence.
Self-assembled peptide monolayers as a toxin sensing mechanism within arrayed microchannels.
Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.
Sensory neuropathy in progressive motor neuronopathy (pmn) mice is associated with defects in microtubule polymerization and axonal transport.
Separation from tryptic digests of casein of some acid-labile components essential in tetanus toxin formation.
Separation of tetanus toxin and toxoid proteins by Sephadex gel.
Sequence homology and structural analysis of the clostridial neurotoxins.
Sequence homology between tetanus and botulinum toxins detected by an antipeptide antibody.
Sequencing and phylogenetic analysis of neurotoxin gene from an environmental isolate of Clostridium sp.: comparison with other clostridial neurotoxins.
Sequestration of tetanus toxin in developing neuronal cell cultures.
Serological evaluation of a simplified immunization schedule using quadruple DPT-polio vaccine in Burkina Faso.
Serological identification and physical-chemical properties of the non-spasmogenic principle (NSP) in tetanus toxin.
Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis.
Seroprevalence of antibodies to repetitive domains of Plasmodium vivax circumsporozoite protein in United Arab Emirates children.
Serotonin is critical for rewarded olfactory short-term memory in Drosophila.
Serotonin transport is modulated differently by tetanus toxin and growth factors.
Serotonin transporter phosphorylation modulated by tetanus toxin.
Serotonin uptake and release mechanisms in developing cultures of rat embryonic raphe neurons: age- and region-specific differences.
Serum antibodies against haemophilus influenzae type b and tetanus at 2.5 years of age: a follow-up of 2 different regimens of infant vaccination.
Severe tetanus in immunized patients with high anti-tetanus titers.
Significance of circulating toxin and antitoxin in unimmunized tetanus cases of neonates and infants.
Similarities in the heavy and light chains of tetanus toxin suggested by their amino acid compositions.
Simultaneous expression of neuronal and glial properties by chick ciliary ganglion cells during development.
Simultaneous multicolor detection system of the single-molecular microbial antigen with total internal reflection fluorescence microscopy.
Single dopaminergic neurons that modulate aggression in Drosophila.
siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking.
Site of action of tetanus toxin in the central nervous system--subcellular site of binding of tetanus toxin in the cerebrum.
Site-directed primary in vitro immunization: production of HIV-1 neutralizing human monoclonal antibodies from lymphocytes obtained from seronegative donors.
Sm14 of Schistosoma mansoni in fusion with tetanus toxin fragment C induces immunoprotection against tetanus and schistosomiasis in mice.
Smell and taste perception in Drosophila melanogaster larva: toxin expression studies in chemosensory neurons.
SNAP-25 requirement for dendritic growth of hippocampal neurons.
SNARE proteins and rab3A contribute to canalicular formation in parietal cells.
SNARE proteins are critical for regulated exocytosis of ECP from human eosinophils.
SNARE zippering and synaptic strength.
SNARE-mediated rapid lysosome fusion in membrane raft clustering and dysfunction of bovine coronary arterial endothelium.
SNARE-mediated trafficking of alpha5beta1 integrin is required for spreading in CHO cells.
Soleus-specific myopathy induced by passive stretching under local tetanus.
Solid-phase synthesis, conformational analysis and in vitro cleavage of synthetic human synaptobrevin II 1-93 by tetanus toxin L chain.
Solubility of the catalytic domains of Botulinum neurotoxin serotype E subtypes.
Soluble ?Klotho downregulates Orai1-mediated store-operated Ca2+ entry via PI3K-dependent signaling.
Soluble N-ethylmaleimide-sensitive factor attachment protein receptors required during Trypanosoma cruzi parasitophorous vacuole development.
Soluble NSF attachment protein receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment.
Somatodendritic secretion in oxytocin neurons is upregulated during the female reproductive cycle.
Some general rules governing fate and action of polypeptide and protein drugs, as derived from investigations with staphylococcal alpha-toxin, tetanus toxin, and so-calledd crotoxin.
Some immature tetanus toxin-positive cells share antigenic properties with subclasses of glial cells. An immunofluorescence study in the developing nervous system of the mouse using a new monoclonal antibody S1.
Some metabolic changes occurring in skeletal and heart muscles of guinea pigs treated with tetanus toxin.
Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy.
Spatially Selective Dissection of Signal Transduction in Neurons Grown on Netrin-1 Printed Nanoarrays via Segmented Fluorescence Fluctuation Analysis.
Specific antibodies against the Zn(2+)-binding domain of clostridial neurotoxins restore exocytosis in chromaffin cells treated with tetanus or botulinum A neurotoxin.
Specific antibodies in colostrum of north Indian mothers with special reference to their nutritional status.
Specific cathepsin B inhibitor is cell-permeable and activates presentation of TTC in primary human dendritic cells.
Specific peptides of casein pancreatic digestion enhance the production of tetanus toxin.
Specific T cell deletion by transfected human monocytes expressing fas ligand and antigen.
Spine loss and other persistent alterations of hippocampal pyramidal cell dendrites in a model of early-onset epilepsy.
Spontaneous and evoked high-frequency oscillations in the tetanus toxin model of epilepsy.
Spontaneous nerve activity and sensitivity in catfish ampullary electroreceptor organs after tetanus toxin application.
Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map.
Spontaneous peripheral T-cell responses to the IA-2beta (phogrin) autoantigen in young nonobese diabetic mice.
Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains.
Starch granules as a vehicle for the oral administration of immobilized antigens.
Stentian structural plasticity in the developing visual system.
Steps towards the development of a replacement in vitro test for quantification of antibodies to tetanus toxin during potency testing of vaccine.
Stepwise iodination. A general procedure for detoxification of proteins suitable for vaccine development and antiserum production.
Stereotaxic injection of tetanus toxin in rat central nervous system causes alteration in normal levels of monoamines.
Stereotypical physiological properties emerge during early neuronal and glial lineage development in the embryonic rat neocortex.
Stimulation of a memory B cell response does not require primed helper T cells.
Stimulation of the N-methyl-D-aspartate receptor has a trophic effect on differentiating cerebellar granule cells.
Storage and release of ATP from astrocytes in culture.
Strikingly Reduced Amyloid Burden and Improved Behavioral Performance in Alzheimer's Disease Mice Immunized with Recombinant Chimeric Vaccines by Hexavalent Foldable A?1-15 Fused to Toxin-Derived Carrier Proteins.
Strong similarities in antigen fine specificity among DRB1* 1302-restricted tetanus toxin tt830-843-specific TCRs in spite of highly heterogeneous CDR3.
Structural analysis of the catalytic domain of tetanus neurotoxin.
Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity.
Structural and functional substrates of tetanus toxin in an animal model of temporal lobe epilepsy.
Structural basis of tetanus toxin neutralization by native human monoclonal antibodies.
Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity.
Structural determinants of the specificity for synaptic vesicle-associated membrane protein/synaptobrevin of tetanus and botulinum type B and G neurotoxins.
Structural flexibility of the tetanus neurotoxin revealed by crystallographic and solution scattering analyses.
Structural studies on the zinc-endopeptidase light chain of tetanus neurotoxin.
Structure and function of tetanus and botulinum neurotoxins.
Structure of tetanus toxin. Demonstration and separation of a specific enzyme converting intracellular tetanus toxin to the extracellular form.
Structure of tetanus toxin. I. Breakdown of the toxin molecule and discrimination between polypeptide fragments.
Structure of tetanus toxin. II. Toxin binding to ganglioside.
Structure of tetanus toxin. N-Terminal amino acid analysis of the two molecular forms of tetanus toxin and its composite chains.
Structure of tetanus toxin: the arrangement of papain digestion products within the heavy chain-light chain framework of extracellular toxin.
Structure of the receptor binding fragment HC of tetanus neurotoxin.
Structure-based sequence alignment for the beta-trefoil subdomain of the clostridial neurotoxin family provides residue level information about the putative ganglioside binding site.
Structure:function studies of receptors for thyrotropin and tetanus toxin: lipid modulation of effector binding to the glycoprotein receptor component.
Studies of tetanus toxin and antitoxin in human sera. I. Production of high titer tetanus toxin for use in serologic tests.
Studies of tetanus toxin and antitoxin in human sera. II. Comparison of hemagglutination and mouse neutralization tests for determining circulating human tetanus antitoxin.
Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve.
Studies on effects of co-culturing on the development of embryonic and postnatal cerebellar cells.
Studies on immune response to atoxic fragments of tetanus toxin and its denatured antigen.
Studies on tetanus toxin and toxoid. 3. Sedimentation of toxin and derivatives obtained by sulphite and aldehyde treatments.
Studies on tetanus toxin and toxoid. I. Isolation of tetanus toxin using DEAE-cellulose.
Studies on tetanus toxin and toxoid. II. Isolation and characterization of the tetanus toxin and toxoid.
Studies on tetanus toxin and toxoid. IV. Interaction of formaldehyde with tetanus toxin.
STUDIES ON TETANUS TOXIN. I. FORMATION OF INTRAMITOCHONDRIAL DENSE GRANULES IN MICE ACUTELY POISONED WITH TETANUS TOXIN.
STUDIES ON TETANUS TOXIN. II. THE PREPARATION OF PURIFIED TETANUS TOXIN AND ITS FLUORESCENT LABELLING.
Studies on tetanus. V. In vivo localization of purified tetanus neurotoxin in mice with fluorescein-labelled tetanus antitoxin.
Studies on the antibody composition and neutralizing activity of tetanus antitoxin sera from various species of animals in relation to the antigenic substructure of the tetanus toxin molecule.
Studies on the antigenic structure of tetanus toxin.
Studies on the effect of tetanus antitoxin against tetanus toxin.
Studies on the immunotherapy of tetanus. I. Purification and characterization of tetanus toxin.
Studies on the intoxication pathway of tetanus toxin in the rat pheochromocytoma (PC12) cell line. Binding, internalization, and inhibition of acetylcholine release.
STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : VII. THE DIFFERENTIATION OF TETANOLYSIN AND TETANOSPASMIN.
Studies on the toxic action of tetanus toxin. I.
Studies on thermal sedation in suppression of the symptoms of tetanus toxin.
Subcellular fixation of tetanus toxin in susceptible and resistant species.
Subcellular localization of tetanus neurotoxin-insensitive vesicle-associated membrane protein (VAMP)/VAMP7 in neuronal cells: evidence for a novel membrane compartment.
Subcellular localization of the carbohydrate Lewisx adhesion structure in hippocampus cell cultures.
Sublingual immunization with an engineered Bacillus subtilis strain expressing tetanus toxin fragment C induces systemic and mucosal immune responses in piglets.
Sublingually administered Bacillus subtilis cells expressing tetanus toxin C fragment induce protective systemic and mucosal antibodies against tetanus toxin in mice.
Subpopulations of rat cerebellar astrocytes in primary culture: morphology, cell surface antigens and [3H]GABA transport.
Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins.
Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.
Suppression of 3H-acetylcholine release from primary nerve cell cultures by tetanus and botulinum-A toxin.
Supratrigeminal Bilaterally Projecting Neurons Maintain Basal Tone and Enable Bilateral Phasic Activation of Jaw-Closing Muscles.
Surface display of recombinant proteins on Bacillus subtilis spores.
Surface topography of histidine residues of tetanus toxin probed by immobilized-metal-ion affinity chromatography.
Surface-accessible GABA supports tonic and quantal synaptic transmission.
Sustained and selective block of IPSPs in brain slices from rats made epileptic by intrahippocampal tetanus toxin.
SV2 mediates entry of tetanus neurotoxin into central neurons.
Sympathomimetic action of tetanus toxin.
Synapse composition and organization following chronic activity blockade in cultured hippocampal neurons.
Synapse-specific regulation of AMPA receptor subunit composition by activity.
Synaptic activity and activity-dependent competition regulates axon arbor maturation, growth arrest, and territory in the retinotectal projection.
Synaptic and intrinsic control of membrane excitability of neostriatal neurons. II. An in vitro analysis.
Synaptic inhibition in primary and secondary chronic epileptic foci induced by intrahippocampal tetanus toxin in the rat.
Synaptic Plasticity Induced by Differential Manipulation of Tonic and Phasic Motoneurons in Drosophila.
Synaptic structural modification following changes in activity induced by tetanus neurotoxin in cat abducens neurons.
Synaptic targeting of retrogradely transported trophic factors in motoneurons: comparison of glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor, and cardiotrophin-1 with tetanus toxin.
Synaptic transmission in neurons that express the Drosophila atypical soluble guanylyl cyclases, Gyc-89Da and Gyc-89Db, is necessary for the successful completion of larval and adult ecdysis.
Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons.
Synaptic vesicle exocytosis and increased cytosolic calcium are both necessary but not sufficient for activity-dependent bulk endocytosis.
Synaptic-like Vesicles Facilitate Pioneer Axon Invasion.
Synaptobrevin cleavage by the tetanus toxin light chain is linked to the inhibition of exocytosis in chromaffin cells.
Synaptobrevin is essential for secretion but not for the development of synaptic processes.
Synaptobrevin/vesicle-associated membrane protein (VAMP) of Aplysia californica: structure and proteolysis by tetanus toxin and botulinal neurotoxins type D and F.
Synaptobrevin2 is the v-SNARE required for cytotoxic T-lymphocyte lytic granule fusion.
Synaptogyrins regulate Ca2+-dependent exocytosis in PC12 cells.
Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
Synthesis of tetanus toxin fragment C in insect cells by use of a baculovirus expression system.
Synthesis of tumor-associated glycopeptide antigens for the development of tumor-selective vaccines.
Synthetic Cannabinoid-Induced Immunosuppression Augments Cerebellar Dysfunction in Tetanus-Toxin Treated Mice.
Synthetic peptide antigens of tetanus toxin.
Systemic administration of low dosage of tetanus toxin decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus.
Systemic immune response after mucosal immunization in patients with IgA nephropathy.
T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity.
Tandem copies of a human rotavirus VP8 epitope can induce specific neutralizing antibodies in BALB/c mice.
Targeted expression of tetanus neurotoxin interferes with behavioral responses to sensory input in Drosophila.
Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects.
Targeted expression of tetanus toxin reveals sets of neurons involved in larval locomotion in Drosophila.
Targeted expression of tetanus toxin: a new tool to study the neurobiology of behavior.
Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila.
Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c.
Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunologic and Clinical Outcomes.
Targeting the epithelial SNARE machinery by bacterial neurotoxins.
Targeting the R domain of coagulase by active vaccination protects mice against lethal Staphylococcus aureus infection.
Tat-tetanus toxin fragment C: a novel protein delivery vector and its use with photochemical internalization.
Temperature-mediated interaction of tetanus toxin with cerebral neuron cultures: characterization of a neuraminidase-insensitive toxin-receptor complex.
Temporal profile of connexin 43 mRNA expression in a tetanus toxin-induced seizure disorder.
Tentative identification of the tetanus toxin recptor in nervous tissue.
Testing the efficacy of a recombinant merozoite surface protein (MSP-1(19) of Plasmodium vivax in Saimiri boliviensis monkeys.
Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses.
Tetanus and botulinum neurotoxins: turning bad guys into good by research.
Tetanus and botulinum toxins block the release of acetylcholine from slices of rat striatum and from the isolated electric organ of Torpedo at different concentrations.
Tetanus and botulinum toxins inhibit, and black widow spider venom stimulates the release of methionine-enkephalin-like material in vitro.
Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin.
Tetanus and botulism neurotoxins: a novel group of zinc-endopeptidases.
TETANUS and TETANUS NEUROTOXIN: from peripheral uptake to central nervous tissue targets.
Tetanus antibodies as a marker of potential efficacy of killed polio immunization.
Tetanus antitoxin binds to intracellular tetanus toxin in permeabilized chromaffin cells without restoring Ca2(+)-induced exocytosis.
Tetanus immunity in kibbutz women.
Tetanus in animals.
Tetanus insensitive VAMP2 differentially restores synaptic and dense core vesicle fusion in tetanus neurotoxin treated neurons.
Tetanus intoxication causes an increment of serotonin in the central nervous system.
Tetanus neurotoxin HCC protein commits T cells to IFN-? producing cells.
Tetanus Neurotoxin Neutralizing Antibodies Screened from a Human Immune scFv Antibody Phage Display Library.
Tetanus neurotoxin utilizes two sequential membrane interactions for channel formation.
Tetanus neurotoxin-induced epilepsy in mouse visual cortex.
Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion.
Tetanus neurotoxin.
Tetanus neurotoxin: conformational plasticity as an adaptive strategy.
Tetanus of suspected dental causality.
Tetanus seroprevalence among farmers: a preliminary study.
Tetanus toxin abolishes exocytosis of ROMK1 induced by inhibition of protein tyrosine kinase.
Tetanus toxin action on cultured nerve cells does it modify a neuronal protein?
Tetanus toxin action: inhibition of neurotransmitter release linked to synaptobrevin proteolysis.
Tetanus toxin activity and ganglioside content of rat brain.
Tetanus toxin affects the K+-stimulated release of catecholamines from nerve growth factor-treated PC12 cells.
Tetanus toxin alters 5-hydroxytryptamine, dopamine, and their metabolites in rat hippocampus measured by in vivo microdialysis.
Tetanus toxin and amino acid levels in cat spinal cord.
Tetanus toxin and antigenic derivatives. I. Purification of the biologically active monomer.
Tetanus toxin and antigenic derivatives. II. Effect of protein and formaldehyde concentration on toxoid formation.
Tetanus toxin and antitoxin.
Tetanus toxin and axonal transport.
Tetanus toxin and botulinum A and C neurotoxins inhibit noradrenaline release from cultured mouse brain.
Tetanus toxin and botulinum A neurotoxin inhibit and at higher concentrations enhance noradrenaline outflow from particulate brain cortex in batch.
Tetanus toxin and botulinum A toxin inhibit acetylcholine release from but not calcium uptake into brain tissue.
Tetanus toxin and botulinum A toxin inhibit release and uptake of various transmitters, as studied with particulate preparations from rat brain and spinal cord.
Tetanus toxin and botulinum toxin A utilize unique mechanisms to enter neurons of the central nervous system.
Tetanus toxin and botulinum toxins type A and B inhibit glutamate, gamma-aminobutyric acid, aspartate, and met-enkephalin release from synaptosomes. Clues to the locus of action.
Tetanus toxin and Clostridium perfringens enterotoxin as tools for the study of exocytosis.
Tetanus toxin and experimental epilepsy in rats.
Tetanus toxin and muscle relaxation.
Tetanus toxin and neuronal membranes: the relationship between binding and toxicity.
Tetanus toxin and spinal inhibition.
Tetanus toxin and synaptic inhibition in the substantia nigra and striatum of the rat.
Tetanus toxin and the synaptic release of GABA.
Tetanus toxin and thyrotropin interactions with rat brain membrane preparations.
Tetanus toxin as a marker for small-cell lung cancer cell lines.
Tetanus toxin as a neurobiological tool to study mechanisms of neuronal cell death in the mammalian brain.
Tetanus toxin as a tool for studying epilepsy.
Tetanus toxin association with developing neuronal cell cultures. Kinetic parameters and evidence for ganglioside-mediated internalization.
Tetanus toxin attenuates the ability of phorbol myristate acetate to mobilize cytosolic protein kinase C in NG-108 cells.
Tetanus toxin binding to different morphological phenotypes of cultured rat and bovine adrenal medullary cells.
Tetanus toxin binding to isolated and cultured rat retinal glial cells.
Tetanus toxin binding to mouse spinal cord cells: an evaluation of the role of gangliosides in toxin internalization.
Tetanus toxin binding to neuroblastoma cells differentiated by antimitotic agents.
Tetanus toxin binds with high affinity to neuroblastoma x glioma hybrid cells NG 108-15 and impairs their stimulated acetylcholine release.
Tetanus toxin blocks Ca spikes in neuroblastoma clone N1E-115 cells.
Tetanus toxin blocks inhibition of granule cells in the dentate gyrus of the urethane-anaesthetized rat.
Tetanus toxin blocks potassium-induced transmitter release and rearrangement of intramembrane particles at pure cholinergic synaptosomes.
Tetanus toxin blocks the efferent endings in the cochlea.
Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons.
Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum A toxin.
Tetanus toxin C fragment-conjugated nanoparticles for targeted drug delivery to neurons.
Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo.
Tetanus toxin C-fragment: the courier and the cure?
Tetanus toxin channel in phosphatidylserine planar bilayers: conductance states and pH dependence.
Tetanus Toxin cis-Loop Contributes to Light-Chain Translocation.
Tetanus toxin conformation.
Tetanus toxin does not affect the release of noradrenaline and taurine from rat cerebral cortex slices evoked by high K+ and Na+-free media.
Tetanus toxin effect on the metabolism and release of acetylcholine in rat central nervous system.
Tetanus toxin enhances protein kinase C activity translocation and increases polyphosphoinositide hydrolysis in rat cerebral cortex preparations.
Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus.
Tetanus Toxin Forms Channels in Planar Lipid Bilayers Containing Gangliosides.
Tetanus toxin fragment C as a vector to enhance delivery of proteins to the CNS.
Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons.
Tetanus toxin fragment C expressed in live Salmonella vaccines enhances antibody responses to its fusion partner Schistosoma haematobium glutathione S-transferase.
Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine.
Tetanus toxin fragment C fusion facilitates protein delivery to CNS neurons from cerebrospinal fluid in mice.
Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis.
Tetanus toxin fragment forms channels in lipid vesicles at low pH.
Tetanus toxin fragments and Bcl-2 fusion proteins: cytoprotection and retrograde axonal migration.
Tetanus toxin H(C) fragment reduces neuronal MPP(+) toxicity.
Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress.
Tetanus toxin impairs accessory and secretory functions in interferon-gamma-treated murine macrophages.
Tetanus toxin in dissociated spinal cord cultures: long-term characterization of form and action.
Tetanus toxin in the rat hippocampus [proceedings]
Tetanus toxin induced actions on spinal Renshaw cells and Ia-inhibitory interneurones during development of local tetanus in the cat.
Tetanus toxin induces fusion and aggregation of lipid vesicles containing phosphatidylinositol at low pH.
Tetanus toxin induces long-term changes in excitation and inhibition in the rat hippocampal CA1 area.
Tetanus toxin inhibition of K+-stimulated [3H]GABA release from developing cell cultures of the rat cerebellum.
Tetanus toxin inhibits amino acid release from nerve endings in vitro.
Tetanus toxin inhibits depolarization-induced [3H]serotonin release from rat brain cortex synaptosomes.
Tetanus toxin inhibits depolarization-stimulated protein phosphorylation in rat cortical synaptosomes: effect on synapsin I phosphorylation and translocation.
Tetanus toxin inhibits neuroexocytosis even when its Zn(2+)-dependent protease activity is removed.
Tetanus toxin inhibits neurotensin-induced mobilization of cytosolic protein kinase C activity in NG-108 cells.
Tetanus toxin inhibits secretion of lysosomal contents from human macrophages.
Tetanus toxin inhibits spontaneous quantal release and cleaves VAMP/synaptobrevin.
Tetanus toxin inhibits the evoked outflow of an inhibitory (GABA) and an excitatory (D-aspartate) amino acid from particulate brain cortex.
Tetanus toxin interaction with human erythrocytes. I. Properties of polysialoganglioside association with the cell surface.
Tetanus toxin interaction with human erythrocytes. II. Kinetic properties of toxin association and evidence for a ganglioside-toxin macromolecular complex formation.
Tetanus toxin interactions with the thyroid: decreased toxin binding to membranes from a thyroid tumor with a thyrotropin receptor defect and in vivo stimulation of thyroid function.
Tetanus toxin interactions with thyroid plasma membranes. Implications for structure and function of tetanus toxin receptors and potential pathophysiological significance.
Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.
Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1.
Tetanus toxin is labeled with photoactivatable phospholipids at low pH.
Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation.
Tetanus toxin L chain is processed by major histocompatibility complex class I and class II pathways and recognized by CD8+ or CD4+ T lymphocytes.
Tetanus toxin labeling as a novel rapid and highly specific tool in human neuroblastoma differential diagnosis.
Tetanus toxin light chain cleaves a vesicle-associated membrane protein (VAMP) isoform 2 in rat pancreatic zymogen granules and inhibits enzyme secretion.
Tetanus toxin light chain expression in Sertoli cells of transgenic mice causes alterations of the actin cytoskeleton and disrupts spermatogenesis.
Tetanus toxin mechanism of action in Torpedo electromotor system: a study on different steps in the intoxication process.
Tetanus toxin modulates serotonin transport in rat-brain neuronal cultures.
Tetanus toxin potently stimulates tissue transglutaminase. A possible mechanism of neurotoxicity.
Tetanus toxin preserves skeletal muscle contractile force and size during limb immobilization.
Tetanus toxin produces neuronal loss and a reduction in GABAA but not GABAB binding sites in rat hippocampus.
Tetanus toxin production in soy-based medium: nutritional studies and scale-up into small fermentors.
Tetanus toxin production in the absence of protein.
Tetanus toxin production is triggered by the transition from amino acid consumption to peptides.
Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells.
Tetanus toxin receptors on nerve cells contain a trypsin-sensitive component.
Tetanus toxin reduces local and descending regulation of the H-reflex.
Tetanus toxin selectively impairs anti-tumoral but not anti-microbial macrophage-mediated effector functions.
Tetanus Toxin Synthesis is Under the Control of A Complex Network of Regulatory Genes in Clostridium tetani.
Tetanus toxin treatment in vitro inhibits the release of GABA from rat cerebral cortex slices evoked by high K(+) and Na(+)-free media.
Tetanus toxin, a neuromuscular blocking agent.
Tetanus toxin-enhanced GABA immunoreactivity in living neurons.
Tetanus toxin-induced effects on extracellular amino acid levels in rat hippocampus: an in vivo microdialysis study.
Tetanus toxin-induced protein kinase C activation and elevated serotonin levels in the perinatal rat brain.
Tetanus toxin-induced seizures cause microglial activation in rat hippocampus.
Tetanus toxin-induced seizures in infant rats and their effects on hippocampal excitability in adulthood.
Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells.
Tetanus toxin-mediated cleavage of cellubrevin inhibits proton secretion in the male reproductive tract.
Tetanus toxin-sensitive VAMP-related proteins are present in murine macrophages.
Tetanus toxin-[2,3-3H]propionamid. Synthesis, specific activity, immunoreactivity, toxicity and ascent into the spinal cord.
Tetanus toxin.
Tetanus toxin. The effect of chemical modifications on toxicity, immunogenicity, and conformation.
Tetanus toxin: a cell surface marker for neurones in culture.
Tetanus toxin: a marker of amphibian neuronal differentiation in vitro.
Tetanus toxin: a rapid and selective blockade of the calcium, but not sodium, component of action potentials in cultured neuroblastoma N1E-115 cells.
Tetanus toxin: biochemical and pharmacological comparison between its protoxin and some isotoxins obtained by limited proteolysis.
Tetanus toxin: convulsant action on mouse spinal cord neurons in culture.
Tetanus toxin: direct evidence for retrograde intraaxonal transport.
Tetanus toxin: evidence for binding at presynaptic nerve endings.
Tetanus toxin: fine structure localization of binding sites in striated muscle.
Tetanus toxin: Immunocytochemical evidence for retrograde transport.
Tetanus toxin: inhibitory action in chromaffin cells is initiated by specified types of gangliosides and promoted in low ionic strength solution.
Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins.
Tetanus toxin: Retrograde axonal transport of systemically administered toxin.
Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblock-copolymers: immune response in mice.
Tetanus toxoid purification: Chromatographic procedures as an alternative to ammonium-sulphate precipitation.
Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy.
Tetanus vaccine-induced human neutralizing antibodies provide full protection against neurotoxin challenge in mice.
Tetanus--still a topic of present interest: a report of 27 cases from a Belgian referral hospital.
Tetanus.
Tetanus: a diagnostic challenge in the Western world.
Tetanus: a review.
Tetanus: pathophysiology and management.
Tetanus: pathophysiology, treatment, and the possibility of using botulinum toxin against tetanus-induced rigidity and spasms.
TetR is a positive regulator of the tetanus toxin gene in Clostridium tetani and is homologous to botR.
Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition.
TH1/TH2 cytokine balance in patients with both type 1 diabetes mellitus and asthma.
The 25 kDa HCN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity.
The action of clavacin isomer and related compounds on tetanus toxin.
The action of clavacin, a clavacin isomere, and related compounds on tetanus toxin.
The action of tetanus toxin in frogs.
The action of tetanus toxin on preganglionic sympathetic reflex discharges.
The action of tetanus toxin on the acetylcholine and cholinesterase contents of the rabbit's iris.
The action of tetanus toxin on the inhibition of motoneurones.
The action of tetanus toxin on the rabbit's iris.
The action of tetanus toxin.
The action of tetanus toxin: a case report.
The active site structure of tetanus neurotoxin resolved by multiple scattering analysis in X-Ray absorption spectroscopy.
The affinity of the nerve fiber for tetanus toxin.
The amino acid compositions of proteins are correlated with their molecular sizes.
The anticholinesterase activity of tetanus toxin: comparison between intoxication by organophosphoric esters and by tetanus toxin.
THE APPARENT ALTERATION OF TETANUS TOXIN WITHIN THE SPINAL CORD OF DOGS.
The binding fragment from tetanus toxin antagonizes the neuromuscular blocking actions of botulinum toxin.
The binding of tetanus toxin to retinal cells.
The C-terminal domain of tetanus toxin protects motoneurons against acute excitotoxic damage on spinal cord organotypic cultures.
The C-terminal domain of the heavy chain of tetanus toxin given by intramuscular injection causes neuroprotection and improves the motor behavior in rats treated with 6-hydroxydopamine.
The C-terminal domain of the heavy chain of tetanus toxin prevents the oxidative and nitrosative stress induced by acute toxicity of 1-methyl-4-phenylpyridinium, a rat model of Parkinson's disease.
The C-terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurones from apoptotic death: involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways.
The C-terminal fragment of the heavy chain of the tetanus toxin (Hc-TeTx) improves motor activity and neuronal morphology in the limbic system of aged mice.
The C-terminal transmembrane region of synaptobrevin binds synaptophysin from adult synaptic vesicles.
The carboxyl-terminal domain of the heavy chain of tetanus toxin prevents dopaminergic degeneration and improves motor behavior in rats with striatal MPP(+)-lesions.
The CBD1 peptide corresponding to the caveolin-1 binding domain of HIV-1 glycoprotein gp41 elicits neutralizing antibodies in cynomolgus macaques when administered with the tetanus T helper epitope.
The cellular function of MASH1 in autonomic neurogenesis.
The chain composition of tetanus toxin.
The chemical component of the mixed GF-TTMn synapse in Drosophila melanogaster uses acetylcholine as its neurotransmitter.
The Coffin-Lowry syndrome-associated protein RSK2 regulates neurite outgrowth through phosphorylation of phospholipase D1 (PLD1) and synthesis of phosphatidic acid.
The combined use of analytical tools for exploring tetanus toxin and tetanus toxoid structures.
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene.
The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene.
The complete nucleotide sequence of tetanus toxin.
The complete nucleotide sequence of the gene coding for botulinum type C1 toxin in the C-ST phage genome.
The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins.
The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.
The development of oral vaccines based on live attenuated Salmonella strains.
The Effect of Cysteine on Tetanus Toxin.
The Effect of Differentially Designed Fusion Proteins to Elicit Efficient Anti-human Thyroid Stimulating Hormone Immune Responses.
The effect of environmental temperature on the reaction of mice to tetanus toxin.
THE EFFECT OF EOSIN UPON TETANUS TOXIN AND UPON TETANUS IN RATS AND GUINEA-PIGS.
The effect of experimental epilepsy induced by injection of tetanus toxin into the amygdala of the rat on eating behaviour and response to novelty.
The effect of helper epitopes and cellular localization of an antigen on the outcome of gene gun DNA immunization.
THE EFFECT OF IMPURE TETANUS TOXIN ON THE FREQUENCY OF MINIATURE END-PLATE POTENTIALS.
The effect of lanthanum on nerve terminals in goldfish muscle after paralysis with tetanus toxin.
The effect of lysozyme on the production of tetanus toxin. I. Studies with flocculation.
The effect of lysozyme on the production of tetanus toxin. II. Mouse M.L.D.
The effect of N-glycosylation on the expression of the tetanus toxin fragment C in Pichia pastoris.
The Effect of Pepton upon the Production of Tetanus Toxin.
The effect of sclerosis of the nerve trunk on the ascent of tetanus toxin in the sciatic nerve of rabbits and on the development of local tetanus.
The effect of tetanus toxin at the neuromuscular junction in the goldfish.
The effect of tetanus toxin in the goldfish.
The effect of tetanus toxin on boutons terminaux.
The effect of tetanus toxin on in vitro synaptogenesis.
The effect of tetanus toxin on neuromuscular transmission.
The effect of tetanus toxin on the choline esterase activity of the muscles of rats.
The effect of the injection of tetanus toxin into the central nervous system of rabbits.
The effect of the retrograde axonal transport of nerve growth factor on the morphology of adrenergic neurones.
The effect of the treatment of crude tetanus toxin with ganglioside cerebroside complex on sphincter paralysis in the rabbit's eye.
The effect of transection on the ascent of tetanus toxin in the rabbit's spinal cord.
The effectiveness of tetanus toxin on sciatic nerve regeneration: A preliminary experimental study in rats.
The effects of induced hypoxia on the cardiovascular system in dogs poisoned with tetanus toxin.
The effects of tetanus toxin on neuromuscular transmission and on the morphology of motor end-plates in slow and fast skeletal muscle of the mouse.
The effects of tetanus toxin on the motor end-plates of the mouse. An electron microscopic study.
The effects of tetanus toxin on the orbicularis oculi muscle.
The effects of tetanus toxin-induced limbic epilepsy on the exploratory response to novelty in the rat.
THE ELECTRICAL CHARGE OF TOXIN AND ANTITOXIN.
The First International Standard for Antitetanus Immunoglobulin, Human; pharmaceutical evaluation and international collaborative study.
The fixation of tetanus toxin by frog brain.
The fixation of tetanus toxin by ganglioside.
The fixation of tetanus toxin by nervous tissue.
The fixation of tetanus toxin by synaptic membranes.
The fixation of tetanus toxin to the brain stem of guinea-pigs.
The fixation of tetanus toxin, strychnine, serotonin and other substances by ganglioside.
The flocculation of tetanus toxin and toxoid. I.
The flocculations of tetanus toxin and toxoid. II.
The genome sequence of Clostridium tetani, the causative agent of tetanus disease.
The habenula prevents helpless behavior in larval zebrafish.
The HC fragment of tetanus toxin forms stable, concentration-dependent dimers via an intermolecular disulphide bond.
The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction.
The heat shock protein Hsp70 enhances antigen-specific proliferation of human CD4+ memory T cells.
The heavy chain of tetanus toxin can mediate the entry of cytotoxic gelonin into intact cells.
The heterotrimeric G protein Go2 regulates catecholamine uptake by secretory vesicles.
The house dust mite allergen, Dermatophagoides pteronyssinus, promotes type 2 responses by modulating the balance between IL-4 and IFN-gamma.
The hydrophobicities of cholera toxin, tetanus toxin and their components.
The immune response to anti-idiotype antibodies bearing an internal image epitope of tetanus toxin/toxoid. I. Induction of the humoral immune response.
THE IMMUNITY PRODUCED BY THE GROWTH OF TETANUS BACILLI IN THE DIGESTIVE TRACT.
THE IMMUNIZING POWER OF NUCLEOHISTON AND OF HISTON.
The Immunogenicity of the C Fragment of Tetanus Neurotoxin in Production of Tetanus Antitoxin.
The impact of size on particle drainage dynamics and antibody response.
The in vitro detection of botulinum neurotoxin-cleaved endogenous VAMP is epitope-dependent.
The in vitro inhibition of GABA release by tetanus toxin.
THE INCORPORATION OF C 14-LABELED GLUCOSE AND LEUCINE INTO THE BRAIN PROTEINS OF WHITE MICE INJECTED WITH TETANUS TOXIN.
The influence of certain lipids and proteins on the effect of tetanus toxin in mice.
THE INFLUENCE OF CONCENTRATION (GIBSON'S METHOD) ON THE PRESENCE OF TETANUS TOXIN IN BLOOD SERUM.
The influence of striatal stimulation and putative neurotransmitters on identified neurones in the rat substantia nigra.
The influence of tetanus toxin on sympathetic reflex discharges into the renal nerves.
The inhibition by pertussis and tetanus toxins of evoked catecholamine release from intact and permeabilized bovine adrenal chromaffin cells.
The interaction between aminoquinolines and presynaptically acting neurotoxins.
The interaction of tetanus toxin and antitoxin.
The interaction of tetanus toxin and lanthanum at the neuromuscular junction in the goldfish.
The interaction of tetanus toxin with intact bovine adrenal chromaffin cells: binding of toxin and subsequent inhibition of catecholamine release.
The intestinal life cycle of Bacillus subtilis and close relatives.
The involvement of the sympathetic nervous system in tetanus.
The labelling of motor end-plates in skeletal muscle of mice with 125I tetanus toxin.
The large scale production of tetanus toxin. I. Toxin production in media prepared with peptic-tryptic-ereptic digested meat or casein.
The large scale production of tetanus toxin. II. Chemical research in connection with toxin production.
The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings.
The local effects of tetanus toxin on the electron microscopic structure of skeletal muscle fibres of the mouse.
THE LOCALIZED ACTION ON THE SPINAL CORD OF INTRAMUSCULARLY INJECTED TETANUS TOXIN.
The LTR72 mutant of heat-labile enterotoxin of Escherichia coli enhances the ability of peptide antigens to elicit CD4(+) T cells and secrete gamma interferon after coapplication onto bare skin.
The mechanism of action of tetanus toxin: effect on synaptic processes and some particular features of toxin binding by the nervous tissue.
The mechanism of facilitated cell membrane resealing.
The metallo-proteinase activity of tetanus and botulism neurotoxins.
The molecular weight of tetanus toxin.
The Neural Cell Adhesion Molecule Promotes FGFR-Dependent Phosphorylation and Membrane Targeting of the Exocyst Complex to Induce Exocytosis in Growth Cones.
The nucleotide and deduced amino acid sequences of EcoRI fragment containing the 5'-terminal region of Clostridium botulinum type E toxin gene cloned from Mashike, Iwanai and Otaru strains.
The nucleus tegmenti pedunculopontinus and circling behaviour in the rat.
The Peptide Network between Tetanus Toxin and Human Proteins Associated with Epilepsy.
The peripheral action of tetanus toxin.
The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity.
The population structure of Clostridium tetani deduced from its pan-genome.
The Potentiation of Tetanus Toxin by Broth and Serum.
The potentiation of tetanus toxin by broth and serum.
THE PRESERVATION OF TETANUS TOXIN BY THE LYOPHILE PROCESS.
The production of gastric ulceration in rabbits by perivagal injections of tetanus toxin.
The properties of sulfite-treated tetanus toxin.
The recombinant C-terminal fragment of tetanus toxin protects against cholinotoxicity by intraseptal injection of ?-amyloid peptide (25-35) in rats.
The recombinant protein combined vaccine based on the fragment C of tetanus toxin and the cross-reacting material 197.
The Regions on the Light Chain of Botulinum Neurotoxin Type A Recognized by T Cells from Toxin-Treated Cervical Dystonia Patients. The Complete Human T-Cell Recognition Map of the Toxin Molecule.
The relation between the fixation and inactivation of tetanus toxin by ganglioside.
The relationship between the action of tetanus toxin and its binding by membranes and gangliosides.
The restorative effect of intramuscular injection of tetanus toxin C-fragment in hemiparkinsonian rats.
The role of neural activity in the migration and differentiation of enteric neuron precursors.
The role of reduced iron powder in the fermentative production of tetanus toxin.
THE ROLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : V. PHENOMENA OF PASSIVE IMMUNITY IN BLOCKED AND SPLENECTOMIZED MICE.
The role of transglutaminase in the mechanism of action of tetanus toxin.
The secretion of classical and peptide cotransmitters from a single presynaptic neuron involves a synaptobrevin-like molecule.
The Stability of Glutamatergic Synapses Is Independent of Activity Level, but Predicted by Synapse Size.
The Stability of Tetanus Toxin in 50% Glycerine and of Tetanus Antitoxin in Saturated Salt Solution.
The stereotyped behavior syndrome: a new model and proposed therapy.
The structural gene for tetanus neurotoxin is on a plasmid.
The Structure and Classification of Botulinum Toxins.
The structure of the tetanus toxin reveals pH-mediated domain dynamics.
The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding.
The study of clostridial and related toxins. The search for unique mechanisms and common denominators.
The susceptibility of pigeons to tetanus toxin.
The synaptophysin/synaptobrevin complex dissociates independently of neuroexocytosis.
The teratogenic effect of tetanus toxin on the central nervous system of the early chick embryo.
The tetanus neurotoxin-sensitive and insensitive routes to and from the plasma membrane: fast and slow pathways?
The tetanus toxin light chain inhibits exocytosis.
The tetanus toxin model of chronic epilepsy.
The thalamocortical circuit and the generation of epileptic spikes in rat models of focal epilepsy.
The threat of mid-spectrum chemical warfare agents.
The time course of retrograde transsynaptic transport of tetanus toxin fragment C in the oculomotor system of the rabbit after injection into extraocular eye muscles.
The titration of tetanus antitoxin IV. Studies on the sensitivity and reproducibility of the toxin neutralization test.
The toxin binding inhibition test as a reliable in vitro alternative to the toxin neutralization test in mice for the estimation of tetanus antitoxin in human sera.
The transglutaminase hypothesis for the action of tetanus toxin.
The use of antibody Fab fragments specifically directed to two different complementary parts of the tetanus toxin molecule for studying the mode of action of the toxin.
The use of live attenuated Salmonella for oral vaccination.
The use of microcalorimetry to characterize tetanus neurotoxin, pertussis toxin and filamentous haemagglutinin.
The vesicle-associated membrane protein family of proteins in rat pancreatic and parotid acinar cells.
The vSNAREs VAMP2 and VAMP4 control recycling and intracellular sorting of post-synaptic receptors in neuronal dendrites.
Therapeutic Assay with the Non-toxic C-Terminal Fragment of Tetanus Toxin (TTC) in Transgenic Murine Models of Prion Disease.
Therapeutic effects of Tetanus neurotoxin in spinal cord injury: a case series on four dogs.
Three-dimensional structural analysis of tetanus toxin by electron crystallography.
Thyrotropin-releasing hormone has profound presynaptic action on cultured spinal cord neurons.
Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons.
Time evolution of interhemispheric coupling in a model of focal neocortical epilepsy in mice.
Time-course transcriptomics reveals that amino acids catabolism plays a key role in toxinogenesis and morphology in Clostridium tetani.
Toll-like receptor 5 is not essential for the promotion of secretory immunoglobulin A antibody responses to flagellated bacteria.
Towards the Development of Antitumor Vaccines: A Synthetic Conjugate of a Tumor-Associated MUC1 Glycopeptide Antigen and a Tetanus Toxin Epitope This work was supported by the Deutsche Forschungsgemeinschaft and by the Stiftung Rheinland-Pfalz für Innovation. S.K. is grateful for a Kekulé-Stipendium from the Fonds der Chemischen Industrie.
Towards the Development of Antitumor Vaccines: A Synthetic Conjugate of a Tumor-Associated MUC1 Glycopeptide Antigen and a Tetanus Toxin Epitope.
Toxic effects of tetanus toxin on GG2EE macrophages: prevention of gamma interferon-mediated upregulation of lysozyme-specific mRNA levels.
Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.
TOXIN-ANTITOXIN REACTION WITHOUT NEUTRALIZATION.
Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin.
Transcutaneous delivery of tetanus toxin Hc fragment induces superior tetanus toxin neutralizing antibody response compared to tetanus toxoid.
Transcutaneous immunization by merely prolonging the duration of antigen presence on the skin of mice induces a potent antigen-specific antibody response even in the absence of an adjuvant.
Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants.
Transcutaneous immunization with bacterial ADP-ribosylating exotoxins, subunits, and unrelated adjuvants.
Transglutaminase participates in the blockade of neurotransmitter release by tetanus toxin: evidence for a novel biological function.
Transient renal glucosuria in patients with tetanus.
Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region.
Transmembrane TNF-dependent uptake of anti-TNF antibodies.
Transmission at the squid giant synapse was blocked by tetanus toxin by affecting synaptobrevin, a vesicle-bound protein.
Transmitter release in tetanus and botulinum A toxin-poisoned mammalian motor endplates and its dependence on nerve stimulation and temperature.
Transport of cationized anti-tetanus Fab'2 fragments across an in vitro blood-brain barrier model: involvement of the transcytosis pathway.
Transport of tetanus toxin across the rabbit placenta and fetal membranes.
Transsynaptic retrograde labeling in the oculomotor system of the monkey with [125I]tetanus toxin BIIb fragment.
Transsynaptic retrograde transport of fragment C of tetanus toxin demonstrated by immunohistochemical localization.
Transsynaptic transfer of retrogradely transported tetanus protein-peroxidase conjugates.
Transynaptic effects of tetanus neurotoxin in the oculomotor system.
Tumor necrosis factor alpha inhibits the suppressive effect of regulatory T cells on the hepatitis B virus-specific immune response.
Tunicamycin blocks neuritogenesis and glucosamine labeling of gangliosides in developing cerebral neuron cultures.
Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity.
Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture.
Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
Two forms of cerebellar glial cells interact differently with neurons in vitro.
Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics.
Two-dimensional crystals of tetanus toxin.
Types of Tetanus Toxin.
Tyrosine phosphorylation modulates the activity of clostridial neurotoxins.
Tyrosine-1290 of tetanus neurotoxin plays a key role in its binding to gangliosides and functional binding to neurones.
UltramicroELISA for measuring tetanus antitoxin in human sera.
Ultrastructural immunocytochemistry of tetanus toxin binding sites to spinal ganglia of chick embryo in tissue culture.
Ultrastructural localization of the binding fragment of tetanus toxin in putative gamma-aminobutyric acidergic terminals in the intermediolateral cell column: a potential basis for sympathetic dysfunction in generalized tetanus.
Ultrastructure of the spinal cord and the sciatic nerve of rats with tetanus toxin poisoning.
Unidentified Nutrients in Tetanus Toxin Production.
Unidentified nutrients in tetanus toxin production.
Unique ganglioside recognition strategies for clostridial neurotoxins.
Unique gene expression patterns in human T-cell lines generated from multiple sclerosis patients by stimulation with a synthetic MOG peptide.
Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells.
Unveiling the Dual Role of the Dopaminergic System on Locomotion and the Innate Value for an Aversive Olfactory Stimulus in Drosophila.
Uptake of Clostridial Neurotoxins into Cells and Dissemination.
Use of a diluent containing protein for dilution of potent toxins like tetanus toxin for in vivo tests.
Use of a rationally attenuated Bordetella bronchiseptica as a live mucosal vaccine and vector for heterologous antigens.
Use of Biologic Therapy by Pregnant Women with Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines.
Use of central neuronal cultures for the detection of neuronotrophic agents.
Use of Epstein-Barr virus-transformed B cell lines for the generation of immunoglobulin-producing human B cell hybridomas.
Use of genetic immunization to generate a high-level antibody against rat dicarboxylate transporter.
Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination.
Use of in vitro Vero cell assay and ELISA in the United States potency test of vaccines containing adsorbed diphtheria and tetanus toxoids.
Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var. Typhimurium.
Use of long synthetic peptides to study the antigenicity and immunogenicity of the Plasmodium vivax circumsporozoite protein.
Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins.
Use of the B-IIb tetanus toxin derived fragment as a specific neuropharmacological transport agent.
Use of the neurotoxic agents kainic acid and tetanus toxin in the extrapyramidal system.
Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccine.
Use of the stationary phase inducible promoters, spv and dps, to drive heterologous antigen expression in Salmonella vaccine strains.
Using common spatial distributions of atoms to relate functionally divergent influenza virus n10 and n11 protein structures to functionally characterized neuraminidase structures, toxin cell entry domains, and non-influenza virus cell entry domains.
Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma.
v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells.
V3 spinal neurons establish a robust and balanced locomotor rhythm during walking.
Vaccination with DNA encoding a single-chain TCR fusion protein induces anticlonotypic immunity and protects against T-cell lymphoma.
Vaccine therapy in NHL: future promises and current limitations.
Vaccines against botulism.
VAMP2 is implicated in the secretion of antibodies by human plasma cells and can be replaced by other synaptobrevins.
VAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts.
VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx.
VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion.
VAMPs sensitive to tetanus toxin are required for cortical granule exocytosis in mouse oocytes.
Variable factors influencing the production of tetanus toxin.
Variation of Lf value of tetanus toxin depending on the reference antitoxins for flocculation.
Vasoactive intestinal peptide and electrical activity influence neuronal survival.
Vasopressin and oxytocin in sensory neurones: expression, exocytotic release and regulation by lactation.
Vasopressin Expression in Cultured Neurons is Stimulated by Cyclic AMP.
VEGF increases blood-brain barrier permeability to Evans blue dye and tetanus toxin fragment C but not adeno-associated virus in ALS mice.
Vesicle associated membrane protein 8 (VAMP8)-mediated zymogen granule exocytosis is dependent on endosomal trafficking via the constitutive-like secretory pathway.
Vesicle-associated membrane protein (VAMP)/synaptobrevin-2 is associated with dense core secretory granules in PC12 neuroendocrine cells.
Vesicle-associated Membrane Protein-2 (VAMP2) Mediates cAMP-stimulated Renin Release in Mouse Juxtaglomerular Cells.
Vestibular primary afferent projection to the cerebellum of the rabbit.
Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release.
Viral vector-mediated selective and reversible blockade of the pathway for visual orienting in mice.
Virulence Plasmids of Spore-Forming Bacteria.
Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax.
Vitamin C for preventing and treating tetanus.
Voltage-dependent potassium currents in cultured astrocytes.
Wireless hippocampal neural recording via a multiple input RF receiver to construct place-specific firing fields.
X-ray absorption spectroscopy study of zinc coordination in tetanus neurotoxin, astacin, alkaline protease and thermolysin.
Zero mode waveguides for single-molecule spectroscopy on lipid membranes.
Zif268 and Fos-like immunoreactivity in tetanus toxin-induced epilepsy: reciprocal changes in the epileptic focus and the surround.
Zona incerta neurons projecting to the ventral tegmental area promote action initiation towards feeding.
Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses.
zTrap: zebrafish gene trap and enhancer trap database.
[3H]GABA uptake as a marker for cell type in primary cultures of cerebellum and olfactory bulb.
[A case of cephalic tetanus presenting with opisthotonus]
[A method for determining absorption of antigens or toxins through the skin; general intoxication and death of animals from percutaneous application of diphtheria or tetanus toxin.]
[A new possibility of "non-parenteral" (local) vaccination: immunization per wound (author's transl)]
[A new principle for the quantiative determination of high molecular weight antigens (junction test) and its application to tetanus toxin, serum albumin and ovalbumin]
[A screening procedure for determining tetanus antibody concentrations in blood products]
[A simple method for assaying the activity of adsorbed tetanus toxoids]
[A study of the effect of proteinases on some fractions of tetanus toxin]
[Absorption of tetanus toxin and antitoxin by carbon.]
[ACTION OF HYPERBARIC OXYGEN ON THE TETANUS BACILLUS AND TETANUS TOXIN.]
[Action of immune serum on the sensitivity of the guinea pig to tetanus toxin.]
[ACTION OF TETANUS TOXIN ON PARAMECIUM AURELIA. FACTORS INFLUENCING THE ACTION OF THE TOXIN AND REVERSIBILITY OF THE FIXATION.]
[Action of tetanus toxin on the protozoan cell. Study on Paramecium aurelia.]
[Alteration of the functional organization of the lateral geniculate body after injection of tetanus toxin into it]
[Analgesia following electrostimulation of midbrain nuclei of rats with a pain syndrome of spinal origin]
[Analgesia induced by creation of a generator of excitation in the midbrain]
[Analysis of analgesia induced by the generator of excitation in the dorsal raphe nucleus]
[Analysis of synaptic neurotransmitter release mechanisms using bacterial toxins]
[Anti-tetanus protection in a homogeneous group of vaccinated subjects from the city of Reggio Emilia]
[Anti-tetanus vaccines, serums and immunoglobulins]
[Antibodies against vaccine-preventable diseases in pregnant women and their offspring. Diphtheria, pertussis, tetanus]
[Antibody-induced immunosuppression: a possible mechanism for tetanus immunization failure in infants (author's transl)]
[Anticonvulsive effect of stimulation of the mesencephalic reticular formation in animals with experimental photogenic epilepsy]
[Antigenically active fragments of tetanus neurotoxin (author's transl)]
[Antitoxin neutralization of tetanus toxin bound to cerebral substance]
[Application of theories on extraction of endocellular tetanus toxin. I. Effect of penicillin.]
[Application of theories on extraction of endocellular tetanus toxin. II. Effect of trypsin.]
[Application of theories on extraction of endocellular tetanus toxin. III. Cryoextraction of endobacillary tetanus toxin.]
[Asymmetric distribution of peptide regulators of muscle tonus and substance P in the spinal cord of rats with unilateral hyperactivity of the lumbar enlargement neurons]
[ATTEMPT AT DEMONSTRATION OF DISULFIDE BONDS IN TETANUS TOXIN AND DIPHTHERIA TOXIN.]
[Attenuation of the effects of tetanus toxin in mice after absorption of lanosterol]
[Axonal transport from the nerve ending to the nerve cell body: a pathway for trophic signals and neurotoxins]
[Basal Ganglia Circuit Mechanisms in Cognitive Learning].
[Behavior of serum and erythrocyte cholinesterase in experimental tetanus in rabbits]
[Binding of tetanus toxin by muscle sarcosomes in the presence of antitoxins]
[Binding of tetanus toxin with cerebral substance with and without tetanus toxoid premedication.]
[Biochemical problems in tetanus toxin poisoning.]
[C-terminal fragment of tetanus toxin: its use in neuronal network analysis and its potential as non-viral vector]
[Cardiovascular complications of severe tetanus (author's transl)]
[Certain characteristics of functional changes of the central nervous system in experimental tetanus and mechanism of action of tetanus toxin. I. Phenomenon of irradiation of irritation following stimulation of the tetanic extremity.]
[Change in the evoked potentials in the visual centers of the rat brain following administration of tetanus toxin to the lateral geniculate body]
[Change in the ultrastructure of neuromuscular junctions due to tetanus toxin]
[Changes in the posture of healthy rats following intracranial administration of brain extracts from animals with experimental vestibulopathies]
[Changes in the protein composition of the synaptic structures of the brain of rats in tetanus intoxication]
[Changes in the ratio of quantum-vesicular parameters in the presence of disrupted synaptic transmitter secretion in the neuromuscular junctions of mammals]
[Changes of various lipid fractions in experimental intoxication with diphtheric and tetanic toxins]
[Characteristics of the rhythmic activity of a normal and a damaged heart during hyperactivity of spinal cord preganglionic neurons]
[Chemical assay of tetanus toxin and toxoid. II. N- and C-terminal amino acids]
[Chemical studies of tetanus toxin and toxoid. I. Amine and total amino nitrogen content and quantitative and qualitative composition of amino acids]
[Chlorophyll. III. Behavior in relation to tetanus toxin.]
[Cholinesterase inhibition in nerve tissue of animals intoxicated with tetanus toxin.]
[Combined vitamin K with tetanus toxin in the treatment of poliomyelitis.]
[Comparative evaluation of tetanus toxin and anatoxin.]
[Comparative immunochemical study of the antigenic makeup of native tetanus toxin from sporulating and nonsporulating C1. tetani strains]
[Comparative study of the antitoxic properties of the sera of birds immunized with tetanus toxin and toxoid]
[Comparison of the anticholinesterase action in vitro of tetanus toxin and parathion]
[Compensatory effect developed by oximes in comparison with cholinesterase inhibited in vitro by tetanus toxin]
[Competition of an oxime in the binding of cholinesterase and tetanus toxin]
[Competitive relations between tetanus anatoxin and toxin]
[Condition of lymphoid tissue and characteristics of development of antitoxin immunity during an experimental course of methotrexate treatment]
[Conditional cell targeting and reversible synapse silencing to study neural circuits]
[Construction of gene vaccine of myostatin fusion with T-helper epitope and its effects on forelimb grip in immunized mice].
[Contractile proteins of nerve endings as a possible target of the presynaptic action of tetanus toxin]
[Contribution to the study of methods of purification of anatoxins. 3. Purification and concentration of tetanus toxin for the purpose of preparation of adsorbed purified anatoxin. Preliminary note]
[Convulsion threshold during tetanus toxin poisoning as the index of the functional state of the central nervous system.]
[Course of experimental tetanus following administration of tetanus toxin in organs innervated by the cranial nerves.]
[Design of chimeric proteins based on a pentameric superhelical fragment of COMP. II. Properties of a hybrid, containing an VNTR (MUC1) antigen of human tumors]
[Design of chimeric proteins based on pentameric superhelical fragments of COMP. I. Properties of a hybrid containing an immunodominant segment of the surface protein of Plasmodium falciparum]
[DETECTION OF TETANUS TOXIN IN THE BRAIN, SPINAL CORD AND SCIATIC NERVE OF FROGS DEAD FROM EXPERIMENTAL INTOXICATION.]
[Determination of tetanus toxin and toxoid by ELISA using monoclonal antibodies]
[Detoxification of tetanus toxin by microorganisms]
[Detoxification of tetanus toxin by the in-vitro action of a pralidoxime]
[Detoxification of tetanus toxin]
[Development of an animal model of autonomic over-activity in tetanus]
[Disorder of ophthalmotonus regulation after formation of a generator of pathologically enhanced hippocampus stimulation]
[Distinct roles of the direct and indirect pathways in the basal ganglia circuit mechanism].
[Distribution of Clostridium tetani in topsoil from Sagamihara, central Japan]
[Distribution of radioactive tetanus toxin at the subcellular level]
[Distribution of radioactive tetanus toxin in the body of experimental animals. 3]
[DNA and proteins in the regenerating liver of rats treated with tetanus toxin]
[Effect of diazepam on the epileptic activity of rats with experimental photogenic epilepsy]
[Effect of diphtheria and tetanus toxin on various types of cells cultured in vitro.]
[Effect of Guaiacuran on the EEG in rabbits poisoned with tetanus toxin.]
[Effect of neurotropic toxins on hydrosoluble proteins of nerve tissue. II. Tetanus toxin.]
[Effect of Penicillium glausum on tetanus toxin.]
[Effect of tetanus toxin and colchicine on synaptic membranes of rat cerebral cortex]
[Effect of tetanus toxin on electrokinetic properties of blood serum proteins]
[Effect of tetanus toxin on K+ and Na+ concentration in synaptosomes]
[Effect of tetanus toxin on mechanisms by which calcium ions regulate transmitter secretion at the neuromuscular junction]
[Effect of tetanus toxin on noradrenaline release from rat brain synaptosomes]
[Effect of tetanus toxin on rat liver]
[Effect of tetanus toxin on the activity of the 5-hydroxytryptaminergic system in the mouse brain]
[Effect of tetanus toxin on the amino acid level of the erythrocytes and plasma of guinea pigs]
[Effect of tetanus toxin on the contractile capacity of actomyosin-like proteins of the rat cerebral cortex]
[Effect of tetanus toxin on the interoceptors of the carotid sinus.]
[Effect of tetanus toxin on the mechanisms of presynaptic spinal inhibition]
[Effect of tetanus toxin on the myocardium]
[EFFECT OF TETANUS TOXIN ON THE MYONEURAL JUNCTION.]
[Effect of tetanus toxin on the plasma levels of protein fractions and electrolytes in guinea pigs]
[Effect of tetanus toxin on the transaminase activity in the liver and amino-nitrogen content of the plasma and erythrocytes in guinea pigs]
[Effect of tetanus toxin poisoning on the metabolic turnover of brain 5-hydroxytryptamine]
[Effect of tetanus toxin suppression of inhibitory processes on changes in RNA content of spinal motor neurons caused by motor activity]
[Effect of the administration of lanosterol on the rat exposed to an injection of tetanus toxin]
[Effect of whole-body x-ray irradiation on the formation of immunity in mice immunized with tetanus anatoxin. I. Primary immunity to tetanus toxin]
[Effect of whole-body x-ray irradiation on the formation of immunity in mice immunized with tetanus toxoid. II. Secondary immunity to tetanus toxin]
[Effect on the organism of sublethal doses of tetanus toxin administered repeatedly.]
[Effective simultaneous immunization with living brucellosis vaccine and with tetanus toxin.]
[Effects of diphtheria and tetanus toxins on liver regeneration in the rat]
[Effects of macromolecular substances (polyvinylpyrrolidone and starch derivatives) on experimental tetanus toxin poisoning.]
[Effects of tetanus toxin and endotoxin of Escherichia coli dyspepsiae on mitotic activities.]
[Electrotonic potentials of spinal cord dorsal roots in frogs with experimental tetanus]
[Existence of tetanus toxin under several aggregation conditions.]
[Experience of two cases of tetanus without a clear history of trauma].
[Experimental determination of the average lethal dose L.D.50 of tetanus toxin. Its importance and its variations.]
[Experimental findings on the paths of tetanus toxin dissemination]
[Experimental neuropathological syndromes during the development of hyperactive determinant dispatch stations in the caudate nuclei]
[Experimental pain and pruritic syndromes of thalamic origin]
[Experimental stereotypy caused by disorders of GABA-ergic mechanisms in the caudate nuclei]
[EXPERIMENTAL STUDIES ON THE EFFECT OF POLYVINYLPYRROLIDONE ON TETANUS TOXIN.]
[Expression, purification of tetanus toxin C fragment/cardiotrophin-1 recombinant fusion protein, target delivery to CNS and neurotrophy biology ability]
[Extraction and various characteristics of radioactive tetanus toxin. I]
[FINDINGS ON CONTENT OF TETANUS TOXIN IN THE BRAIN, SPINAL CORD AND SCIATIC NERVE OF FROGS AFTER INTRODUCTION IN THE DORSAL LYMPHATIC SAC OF A MASSIVE DOSE OF TOXIN.]
[Fixation by lyophilization of the properties of the inoculum strain at an optimum stage for the production of tetanus toxin]
[Fixation of tetanus toxin in the system.]
[Formation of a generator of excitation in the gigantocellular nucleus of the medulla oblongata during disruption of inhibitory processes]
[Formation of a generator of pathologically enhanced excitation in the caudate nucleus in experimental parkinsonism]
[Formation of tetanus toxin with suspensions of microorganisms.]
[From biotechnology to bacterial toxins and immunomodulators]
[Ganglioplegics in experimental poisoning induced with tetanus toxin.]
[Gene cloning, optimized expression and immunogenicity evaluation of tetanus toxin fragment C]
[Generalized tetanus with intractable autonomic cardiovascular instability in an aged woman]
[Generators of pathologically enhanced excitation as determinant structures in the spinal cord]
[Hemolytic action of tetanus toxin.]
[Human plasmacytoid dendritic cells from patients with chronic hepatitis B induce the generation of CD4+CD25+Treg in vitro.]
[Immunity in guinea pigs following administration of tetanus toxin, antitoxin and anatoxin]
[Immunization against tetanus - studies about the duration of protection (author's transl)]
[Immunization of foals against tetanus toxin. 3. Active immunization of newborn and young foals from specifically pretreated mares]
[Immunization of foals against tetanus toxin. II. Transmission of tetanus antibodies with the colostrum to newborn foal and subsequent active immunization]
[Immunochemical characteristics of the antigenic makeup of native tetanus toxin]
[Immunoenzimatic detection of the Clostridium tetani bacterial toxin: an alternative to mice bioassays]
[Immunological and biological study of subunits of tetanus toxin]
[In vitro immunization for the production of antibodies to tetanus toxin and toxoid. 1. Systems for the detection of in vitro synthetized specific immunoglobulins. Strategies of test development]
[In vitro immunization for the production of antibodies to tetanus toxin and toxoid. 2. Antibody production in lymphocyte cultures]
[Increase in glutamate decarboxylase activity in the synaptosomes after treatment with tetanus toxin]
[Industrial production of high-titer tetanus toxin.]
[Inhibition of tetanus poisoning by vitamin B-1]
[Inhibition of the function of the thyroid gland in experimental poisoning by tetanus toxin.]
[Inhibition of the reaction between tetanus toxoid-sensitized lymphocytes and tetanus toxin by tetanus antitoxin (author's transl)]
[Inhibitory action developed by tetanus toxin on serum and neural cholinesterases in various animals]
[Intercentral relations in rat spinal cord with local depression of the inhibitory processes]
[Interference between tetanus toxin and "parathion' in experimental intoxication of animals (author's transl)]
[Investigations into the immunization of foals against tetanus toxin. 1. The transmission of tetanus antibodies by colostrum to newborn and young foals, with reference to hematological and electrophoric findings]
[Level of protection against tetanus in an outpatient population]
[Manifestations of neurotropic antagonism between vitamin B1 and tetanus toxin.]
[Mechanism of action and therapeutic uses of botulinum and tetanus neurotoxins]
[Mechanism of paradoxical resistance of the digastric muscle to the action of tetanus toxin]
[Modeling neuropathologic syndromes by creating generators of pathologically enhanced excitation in the hypothalamus of rabbits]
[Molecular mechanism of action of tetanus toxin and botulinum neurotoxins]
[Molecular organization of the tetanus toxin in relation to the characteristics of its biological activities]
[Neurologic-psychiatric follow-up studies of reanimated tetanus patients (author's transl)]
[Neuronal activity in an epileptic focus formed as a result of the effect of tetanus toxin on the motor area of the cat cerebral cortex]
[Neuropathologic effects developing after administration of tetanus toxin to several rat brain structures]
[Neurosecretory disorders in neuromuscular junctions of a muscle poisoned by tetanus toxin]
[Neutralization of tetanus toxin in the body]
[OF ACTION OF TETANUS TOXIN AS POISON.]
[On certain characteristics of functional changes of the central nervous system in experimental tetanus and on the mechanisms of action of tetanus toxin. II. Role of spinal mechanisms in convulsions and in spastic syndrome in tetanus.]
[On some features of the changes of the functional state of the central nervous system in experimental tetanus and the mechanisms of action of tetanus toxin. Part III. On the central and peripheral action of tetanus toxin.]
[On the detoxication function of stored iron. Experimental animal research on the detoxication of tetanus toxin by hemosiderin and reducing substances. II.]
[On the effect of hydrogen peroxide on tetanus toxin in skin wounds]
[On the mode of action of tetanus toxin in rabbit. I. Distribution of tetanus toxin in vivo and development of paralytic signs under some conditions.]
[On the problem of the mechanism of immunity to tetanus toxin early after active immunization.]
[ON THE PROBLEM OF TRANSFER OF TETANUS TOXIN FROM THE MOTHER TO THE INFANT THROUGH THE PLACENTA. OBSERVATIONS ON THE ALBINO MOUSE.]
[On the sensitivity, resistance and tolerance of rats of various ages to tetanus toxin.]
[Oxidative phosphorylation in rat spinal cord mitochondria in tetanus]
[Parellelism in the behavior of the frog, in the resistance and receptivity according to temperature, with respect to organophosphorus poisons and tetanus toxin]
[Pathogenesis of stereotyped behavior]
[Pathogenetic factors in experimental photogenic epilepsy]
[Pathways of entrance of tetanus toxin into the central nervous system and certain problems of the pathogenesis of experimental tetanus. I. Experiments on white rats.]
[Pathways of entrance of tetanus toxin into the central nervous system and some problems in the pathogenesis of experimental tetanus. I. Experiments on mice, guinea pigs, rabbits and cats.]
[PCR-based assembly of the DNA sequence coding for tetanus toxin C fragment.]
[Permeability of the guinea pig lung to tetanus toxin.]
[Pharmacokinetic peculiarities of tetanus toxin and their relation to the pathogenesis of local or generalized tetanus]
[Pharmacological observations on the interaction between tetanus toxin and convulsants (strychnine and phenol).]
[Photogenic epilepsy with localization of the generator of excitation in the lateral geniculate body (the phenomenon of a determining dispatch station)]
[Physico-chemical studies of purified tetanus toxin and toxoid. I. Chromatographic, electrophoretic and oscillopolarographic studies]
[Physico-chemical studies of purified tetanus toxin and toxoid. II. Infrared studies]
[Possible anticholinesterase activity of the tetanus toxin]
[Possible anticholinesterasic action of tetanus toxin in the pathogenesis of tetanus]
[Possible interference between tetanus toxin and organo-phosphorus esters in blocking of cholinesterase]
[Presynaptic nature of the extinction by tetanus toxin of postsynaptic inhibition]
[Prevalence of tetanus toxin antibodies in the population of Genoa in relation to age and sex]
[Problem of focal pathology in "genuine" epilepsy]
[Procedures of fractional isolation of fragment beta from tetanus toxin (T beta) and a coupling preparation of T beta-HRP]
[Production and immunogenicity analysis of conformation-stable fragment-C mutant of tetanus toxin].
[Production and purification of tetanus toxin]
[PRODUCTION OF LINES OF PARAMECIA SENSITIZED TO TETANUS TOXIN.]
[Production of tetanus toxin on dry casein-vegetative media]
[Progress on lactococcus lactis expressing heterologous antigens as live mucosal vaccines]
[Prolongation of sleep following creation of a generator of pathologically enhanced excitation in the orbital cortex]
[Protagon binding of tetanus toxin neutralized by antitoxin]
[PROTECTIVE ACTION OF TISSUE BASIC POLYPEPTIDES ON EXPERIMENTAL TETANUS TOXIN POISONING IN GUINEA PIGS.]
[Proteolytic enzymes of tetanus toxin and their significance for its stability.]
[Quantitative characteristics of ultrastructural changes in axo-dendritic synapses under the influence of tetanus toxin]
[Radioprotective effectiveness of the paramunity inducer "pind-avi": investigation using the model "protective tetanic vaccination in mice" after exposure to X-rays (author's transl)]
[Rate of elimination of ammonia from the blood of sheep, healthy horses and horses hyperimmunized with Erysipelothrix or tetanus toxin]
[Reaction of eserinized chickens to inoculation of tetanus toxin (preliminary note)]
[Regulation of tetanus toxin-inhibited transmitter secretion in the neuromuscular junction in a calcium-free medium]
[Relation between the decrease of toxicity and formol fixation during the transformation of tetanus toxin to anatoxin.]
[Relation of blood level of specific anatoxin to the degree of immunity to tetanus toxin in white mice immunized with adsorbed tetanus anatoxin.]
[Relationship between the routes of antitoxin administration and the effectiveness of treating experimental tetanus]
[Relationship between the severity of the course of tetanus poisoning and the resistance level of the macroorganism]
[Research on factors affecting neonatal tetanus and its prevention through immunization]
[RESEARCH ON LEVEL OF TETANUS TOXIN IN THE BLOOD OF ALBINO MICE IN THE HOURS FOLLOWING SUBCUTANEOUS INTRODUCTION OF A MASSIVE DOSE OF TOXIN.]
[Research on the peripheral action of tetanus toxin.]
[Role of acetylcholine in tetanus toxin poisoning.]
[Role of tetanus toxin and endotoxins of coli dispepsiae in the mitotic activity of the organism.]
[Role of the receptors of the organ in susceptibility to tetanus toxin and to anti-tetanus serum.]
[Round Table: Immunological urticaria mediated by IgE]
[Routes of penetration of tetanus toxin into the central nervous system and some problems of the pathogenesis of experimental tetanus. III. Experiments on monkeys and dogs.]
[Routes of uptake of tetanus toxin into the central nervous system and some problems of the pathogenesis of experimental tetanus. IV. On the pathogenesis of ascending and descending tetanus.]
[Separation of the toxic component of incompletely detoxified tetanus toxin on DEAE-cellulose]
[Sequelae of administration of tetanus toxin into the vagus nerve.]
[Serological study carried out in Cambodia during a tetanus vaccination in adults]
[Shiga toxin and tetanus toxin as a potential biologic weapon].
[Significance of doses and intervals in summation of stimulation with tetanus toxin.]
[Spinal cord electrical activity during focal depression of inhibitory processes]
[Split tetanus vaccine. Studies on its efficacy and tolerance as compared to adsorbed vaccine]
[Statistical analysis of the structure of a train of miniature endplate potentials following different treatments of the process of transmitter secretion]
[STUDIES ON CULTURE MEDIA FOR THE PRODUCTION OF TETANUS TOXIN.]
[Studies on diphtherial toxin and antitoxin and on tetanus toxin in golden hamster.]
[Studies on the cause of death in tetanus. V. Investigations "in vitro" of aerobic and anaerobic respiration of tissues of mice inoculated with tetanus toxin. (Preliminary note)]
[Studies on the structure of tetanus toxin by means of a diffusion gel precipitation method.]
[STUDIES USING NON MYELINATED NERVE FIBERS ON THE SITE OF THE EFFECT OF BOTULINUM AND TETANUS TOXIN.]
[Study of the pancreatic digestion of casein for th production of tetanus toxin.]
[Study on the effect of a biostimulant on the growth and toxigenic function of Clostridium tetani strain Copenhagen-471]
[Suprasegmentary inhibition and facilitation following administration of tetanus toxin to nuclei of the medulla oblongata (concerning the "starting point" phenomenon)]
[Syndromes of food hypermotivation in hyperactivity of lateral hypothalamic structures in rabbits]
[Synergism of experimental potentiation of penicillin by oxidoreductors and reductors on tetanus toxin.]
[Technic for studying antitetanus immunity]
[Tetanus and botulinum toxins are zinc metallopeptidases: molecular mechanisms and inhibition of their neurotoxicity]
[Tetanus following an abrasion injury]
[Tetanus prevention in a hospital emergency department]
[Tetanus toxin (author's transl)]
[Tetanus toxin and antitoxin. Electrophoretic research.]
[Tetanus toxin and formol.]
[Tetanus toxin and oxygen]
[Tetanus toxin and the mechanism of central depression]
[Tetanus toxin disturbance of 3H-GABA transport in the synaptosomes]
[Tetanus toxin I-131 absorption from the muscles and distribution in the organism]
[Tetanus toxin production. 1. Peptone-free medium for the toxin production with special reference to the significance of the bovine heart infusion]
[Tetanus toxin.]
[The anti-tetanus serumprophylaxis (author's transl)]
[The corticospinal tract and its role in motor control].
[The effect of antitoxin on fixation of tetanus toxin by the subcellular structures of the brain]
[The effect of several substances of the phenothiazine series and alpha-adrenoblockers on spinal cord activity with inhibitory mechanisms disrupted by tetanus toxin]
[THE FATE OF LABELED TETANUS TOXIN IN THE ANIMAL ORGANISM.]
[The preventive properties and therapeutic efficacy of an antitetanus immunoglobulin for experimental intravenous administration]
[The production of tetanus toxin.]
[The properdin level in cattle during immunization and hyperimmunization with Escherichia coli, Pasteurella and tetanus toxin]
[The purification of tetanus toxin and antitoxin.]
[The receptor of tetanus toxin in nerve tissue.]
[The standardization of the in-vitro tetanus toxin neutralization test on Chinese hamster ovary cells]
[The structure and function of botulinum type C neurotoxin]
[The structure and mechanism of action of clostridial neurotoxins]
[TITRATION OF TETANUS TOXIN IN BLOOD OF THE FROG AFTER ADMINISTRATION OF A MASSIVE DOSE OF TOXIN.]
[Two severe tetanus cases infected in an urban area of Kawasaki City]
[Ultramicro-ELISA for measuring tetanus antitoxin in human serum]
[Use of monoclonal antibodies against horse immunoglobulin in an enzyme immunoassay of bacterial toxins and anatoxins]
[Use of the toxin-binding inhibition test for estimation of tetanus antitoxin in serum]
[Value of intrathecal baclofen in the treatment of severe tetanus in the tropical milieu]
Tetany
The effects of tetanus toxin on the orbicularis oculi muscle.
Tremor
Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor.
Trismus
[A case of cephalic tetanus presenting with opisthotonus]
Tuberculosis
Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer's Disease Like Tau Aggregation.
Urinary Retention
Intensive Care Management of Severe Tetanus.
Urticaria
[Round Table: Immunological urticaria mediated by IgE]
Vaccinia
Assessment of a vaccinia virus vectored multi-epitope live vaccine candidate for Plasmodium falciparum.
Virus Diseases
A Salmonella typhimurium htrA live vaccine expressing multiple copies of a peptide comprising amino acids 8-23 of herpes simplex virus glycoprotein D as a genetic fusion to tetanus toxin fragment C protects mice from herpes simplex virus infection.
Whooping Cough
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex.
A recombinant live attenuated strain of Vibrio cholerae induces immunity against tetanus toxin and Bordetella pertussis tracheal colonization factor.
Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age.
Comparison of Corynebacterium parvum and Bordetella pertussis with Freund's complete adjuvant as immunopotentiators for beta-human chorionic gonadotropin linked to an atoxic fragment of tetanus toxin.
Concomitant administration of diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) with pentavalent rotavirus vaccine in Japanese infants.
Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus.
Ensilicated tetanus antigen retains immunogenicity: in vivo study and time-resolved SAXS characterization.
Entrapping of impermeant probes of different size into nonpermeabilized synaptosomes as a method to study presynaptic mechanisms.
Expression and purification of a trivalent pertussis toxin-diphtheria toxin-tetanus toxin fusion protein in Escherichia coli.
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.
Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens.
High level heterologous expression in E. coli using mutant forms of the lac promoter.
High level heterologous expression in E. coli using the anaerobically-activated nirB promoter.
Humoral and cellular immune responses in mice immunized with recombinant Mycobacterium bovis Bacillus Calmette-Guérin producing a pertussis toxin-tetanus toxin hybrid protein.
Immunogenicity and reactogenicity of a single dose of a diphtheria--tetanus--acellular pertussis component vaccine (DTaP) compared to a diphtheria--tetanus toxoid (Td) and a diphtheria toxoid vaccine (d) in adults.
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
Measuring immunoglobulin g antibodies to tetanus toxin, diphtheria toxin, and pertussis toxin with single-antigen enzyme-linked immunosorbent assays and a bead-based multiplex assay.
Neutralizing antibodies and immunoprotection against pertussis and tetanus obtained by use of a recombinant pertussis toxin-tetanus toxin fusion protein.
New combination vaccines: DTaP-IPV (Kinrix) and DTaP-IPV/Hib (Pentacel).
Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach.
Pneumococcal Surface Protein A does not affect the immune responses to a combined diphtheria tetanus and pertussis vaccine in mice.
Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes.
Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis.
Tetanus toxin fragment C-specific priming by intranasal infection with recombinant Bordetella pertussis.
The inhibition by pertussis and tetanus toxins of evoked catecholamine release from intact and permeabilized bovine adrenal chromaffin cells.
The use of microcalorimetry to characterize tetanus neurotoxin, pertussis toxin and filamentous haemagglutinin.
[Antibodies against vaccine-preventable diseases in pregnant women and their offspring. Diphtheria, pertussis, tetanus]
Wound Infection
Insights in metabolism and toxin production from the complete genome sequence of Clostridium tetani.