Reference on EC 3.4.24.26 - pseudolysin
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Nishino, N.; Powers, J.C.
Pseudomonas aeruginosa elastase. Development of a new substrate, inhibitors, and an affinity ligand
J. Biol. Chem.
255
3482-3486
1980
Pseudomonas aeruginosa
Black, W.J.; Quinn, F.; Tompkins, L.S.
Legionella pneumophila zinc metalloprotease is structurally and functionally homologous to Pseudomonas aeruginosa elastase
J. Bacteriol.
172
2608-2613
1990
Legionella pneumophila
Morihara, K.; Tsuzuki, H.
Pseudomonas aeruginosa elastase. Affinity chromatography and some properties as a metalloneutral proteinase
Agric. Biol. Chem.
39
1123-1128
1975
Pseudomonas aeruginosa
-
Morihara, K.
Pseudolysin and other pathogen endopeptidases of thermolysin family
Methods Enzymol.
248
242-253
1995
Pseudomonas aeruginosa, Vibrio cholerae serotype O1
Bever, R.A.; Iglewski, B.H.
Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene
J. Bacteriol.
170
4309-4314
1988
Pseudomonas aeruginosa
Kessler, E.; Safrin, M.; Gustin, J.K.; Ohman, D.E.
Elastase and the LasA protease of Pseudomonas aeruginosa are secreted with their propeptides
J. Biol. Chem.
273
30225-30231
1998
Pseudomonas aeruginosa
Mariencheck, W.I.; Alcorn, J.F.; Palmer, S.M.; Wright, J.R.
Pseudomonas aeruginosa elastase degrades surfactant proteins A and D
Am. J. Respir. Cell Mol. Biol.
28
528-537
2003
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Dulon, S.; Leduc, D.; Cottrell, G.S.; D'Alayer, J.; Hansen, K.K.; Bunnett, N.W.; Hollenberg, M.D.; Pidard, D.; Chignard, M.
Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells
Am. J. Respir. Cell Mol. Biol.
32
411-419
2005
Pseudomonas aeruginosa, Pseudomonas aeruginosa (P14756)
Besson, C.; Saulnier, J.; Wallach, J.M.
Synthetic peptide substrates for a conductimetric assay of Pseudomonas aeruginosa elastase
Anal. Biochem.
237
216-223
1996
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Burns, F.R.; Paterson, C.A.; Gray, R.D.; Wells, J.T.
Inhibition of Pseudomonas aeruginosa elastase and Pseudomonas keratitis using a thiol-based peptide
Antimicrob. Agents Chemother.
34
2065-2069
1990
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Poncz, L.
Substrate inhibition of Pseudomonas aeruginosa elastase by 3-(2-furyl)acryloyl-glycyl-L-phenylalanyl-L-phenylalanine
Arch. Biochem. Biophys.
266
508-515
1988
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Padrines, M.; Bieth, J.G.
Oxidized and Met358-->Leu mutated alpha 1-proteinase inhibitor as substrates of Pseudomonas aeruginosa elastase
Biochim. Biophys. Acta
1163
61-66
1993
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Saulnier, J.M.; Curtil, F.M.; Duclos, M.C.; Wallach, J.M.
Elastolytic activity of Pseudomonas aeruginosa elastase
Biochim. Biophys. Acta
995
285-290
1989
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Kocabiyik, S.; Ergin, E.; Turkoglu, S.
Effects of metals on elastase from Pseudomonas aeruginosa SES-938-1
Biol. Trace Elem. Res.
50
25-31
1995
Pseudomonas aeruginosa, Pseudomonas aeruginosa SES-938-1
Kessler, E.; Spierer, A.
Inhibition by phosphoramidon of Pseudomonas aeruginosa elastase injected intracorneally in rabbit eyes
Curr. Eye Res.
3
1075-1078
1984
Pseudomonas aeruginosa
Spierer, A.; Kessler, E.
The effect of 2-mercaptoacetyl-L-phenylalanyl-L-leucine, a specific inhibitor of Pseudomonas aeruginosa elastase, on experimental Pseudomonas keratitis in rabbit eyes
Curr. Eye Res.
3
645-650
1984
Pseudomonas aeruginosa
Jones, A.; Elphick, H.; Pettitt, E.; Everard, M.L.; Evans, G.S.
Colistin stimulates the activity of neutrophil elastase and Pseudomonas aeruginosa elastase
Eur. Respir. J.
19
1136-1141
2002
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Morihara, K.; Tsuzuki, H.; Oda, K.
Protease and elastase of Pseudomonas aeruginosa: inactivation of human plasma alpha 1-proteinase inhibitor
Infect. Immun.
24
188-193
1979
Pseudomonas aeruginosa (P14756)
Kessler, E.; Israel, M.; Landshman, N.; Chechick, A.; Blumberg, S.
In vitro inhibition of Pseudomonas aeruginosa elastase by metal-chelating peptide derivatives
Infect. Immun.
38
716-723
1982
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Heck, L.W.; Morihara, K.; McRae, W.B.; Miller, E.J.
Specific cleavage of human type III and IV collagens by Pseudomonas aeruginosa elastase
Infect. Immun.
51
115-118
1986
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Poncz, L.; Jentoft, N.; Ho, M.C.; Dearborn, D.G.
Kinetics of proteolysis of hog gastric mucin by human neutrophil elastase and by Pseudomonas aeruginosa elastase
Infect. Immun.
56
703-704
1988
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Bejarano, P.A.; Langeveld, J.P.; Hudson, B.G.; Noelken, M.E.
Degradation of basement membranes by Pseudomonas aeruginosa elastase
Infect. Immun.
57
3783-3787
1989
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Hse, C.C.; Finkelstein, R.A.
Comparison of the Vibrio cholerae hemagglutinin/protease and the Pseudomonas aeruginosa elastase
Infect. Immun.
58
4011-4015
1990
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Kawamoto, S.; Shibano, Y.; Fukushima, J.; Ishii, N.; Morihara, K.; Okuda, K.
Site-directed mutagenesis of Glu-141 and His-223 in Pseudomonas aeruginosa elastase: catalytic activity, processing, and protective activity of the elastase against Pseudomonas infection
Infect. Immun.
61
1400-1405
1993
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Wolz, C.; Hohloch, K.; Ocaktan, A.; Poole, K.; Evans, R.W.; Rochel, N.; Albrecht-Gary, A.M.; Abdallah, M.A.; Doring, G.
Iron release from transferrin by pyoverdin and elastase from Pseudomonas aeruginosa
Infect. Immun.
62
4021-4027
1994
Pseudomonas aeruginosa (P14756)
Azghani, A.O.; Baker, J.W.; Shetty, S.; Miller, E.J.; Bhat, G.J.
Pseudomonas aeruginosa elastase stimulates ERK signaling pathway and enhances IL-8 production by alveolar epithelial cells in culture
Inflamm. Res.
51
506-510
2002
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Kessler, E.; Kennah, H.E.; Brown, S.I.
Pseudomonas protease. Purification, partial characterization, and its effect on collagen, proteoglycan, and rabbit corneas
Invest. Ophthalmol. Vis. Sci.
16
488-497
1977
Pseudomonas aeruginosa
Kessler, E.; Spierer, A.; Blumberg, S.
Specific inhibition of Pseudomonas aeruginosa elastase injected intracorneally in rabbit eyes
Invest. Ophthalmol. Vis. Sci.
24
1093-1097
1983
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Marquart, M.E.; Caballero, A.R.; Chomnawang, M.; Thibodeaux, B.A.; Twining, S.S.; O'Callaghan, R.J.
Identification of a novel secreted protease from Pseudomonas aeruginosa that causes corneal erosions
Invest. Ophthalmol. Vis. Sci.
46
3761-3768
2005
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa (Q5XPI6), Pseudomonas aeruginosa, Pseudomonas aeruginosa PA103 (Q5XPI6)
Fukushima, J.; Yamamoto, S.; Morihara, K.; Atsumi, Y.; Takeuchi, H.; Kawamoto, S.; Okuda, K.
Structural gene and complete amino acid sequence of Pseudomonas aeruginosa IFO 3455 elastase
J. Bacteriol.
171
1698-1704
1989
Pseudomonas aeruginosa, Pseudomonas aeruginosa IFO3455
McIver, K.; Kessler, E.; Ohman, D.E.
Substitution of active-site His-223 in Pseudomonas aeruginosa elastase and expression of the mutated lasB alleles in Escherichia coli show evidence for autoproteolytic processing of proelastase
J. Bacteriol.
173
7781-7789
1991
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
McIver, K.S.; Olson, J.C.; Ohman, D.E.
Pseudomonas aeruginosa lasB1 mutants produce an elastase, substituted at active-site His-223, that is defective in activity, processing, and secretion
J. Bacteriol.
175
4008-4015
1993
Pseudomonas aeruginosa (P14756)
Thayer, M.M.; Flaherty, K.M.; McKay, D.B.
Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution
J. Biol. Chem.
266
2864-2871
1991
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Kessler, E.; Safrin, M.
The propeptide of Pseudomonas aeruginosa elastase acts an elastase inhibitor
J. Biol. Chem.
269
22726-22731
1994
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Heck, L.W.; Alarcon, P.G.; Kulhavy, R.M.; Morihara, K.; Russell, M.W.; Mestecky, J.F.
Degradation of IgA proteins by Pseudomonas aeruginosa elastase
J. Immunol.
144
2253-2257
1990
Pseudomonas aeruginosa, Pseudomonas aeruginosa IFO 3455
Azghani, A.O.; Bedinghaus, T.; Klein, R.
Detection of elastase from Pseudomonas aeruginosa in sputum and its potential role in epithelial cell permeability
Lung
178
181-189
2000
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
McKay, D.B.; Thayer, M.M.; Flaherty, K.M.; Pley, H.; Benvegnu, D.
Crystallographic structures of the elastase of Pseudomonas aeruginosa
Matrix Suppl.
1
112-115
1992
Pseudomonas aeruginosa (P14756)
Braun, P.; Bitter, W.; Tommassen, J.
Activation of Pseudomonas aeruginosa elastase in Pseudomonas putida by triggering dissociation of the propeptide-enzyme complex
Microbiology
146
2565-2572
2000
Pseudomonas aeruginosa (P14756)
-
Braun, P.; Tommassen, J.; Filloux, A.
Role of the propeptide in folding and secretion of elastase of Pseudomonas aeruginosa
Mol. Microbiol.
19
297-306
1996
Pseudomonas aeruginosa (P14756)
Galloway, D.R.
Pseudomonas aeruginosa elastase and elastolysis revisited: recent developments
Mol. Microbiol.
5
2315-2321
1991
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa, Pseudomonas aeruginosa PAO-E64 (P14756)
Barbey-Morel, C.; Perlmutter, D.H.
Effect of pseudomonas elastase on human mononuclear phagocyte alpha 1-antitrypsin expression
Pediatr. Res.
29
133-140
1991
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Matheson, N.R.; Potempa, J.; Travis, J.
Interaction of a novel form of Pseudomonas aeruginosa alkaline protease (aeruginolysin) with interleukin-6 and interleukin-8
Biol. Chem.
387
911-915
2006
Pseudomonas aeruginosa
Gupta, A.; Roy, I.; Khare, S.K.; Gupta, M.N.
Purification and characterization of a solvent stable protease from Pseudomonas aeruginosa PseA
J. Chromatogr. A
1069
155-161
2005
Pseudomonas aeruginosa
Adekoya, O.A.; Willassen, N.P.; Sylte, I.
Molecular insight into pseudolysin inhibition using the MM-PBSA and LIE methods
J. Struct. Biol.
153
129-144
2006
Pseudomonas aeruginosa
Elston, C.; Wallach, J.; Saulnier, J.
New continuous and specific fluorometric assays for Pseudomonas aeruginosa elastase and LasA protease
Anal. Biochem.
368
87-94
2007
Pseudomonas aeruginosa
Lutfullah, G.; Amin, F.; Khan, Z.; Azhar, N.; Azim, M.K.; Noor, S.; Shoukat, K.
Homology modeling of hemagglutinin/protease [HA/P (vibriolysin)] from Vibrio cholerae: Sequence comparision, residue interactions and molecular mechanism
Protein J.
27
105-114
2008
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Kida, Y.; Higashimoto, Y.; Inoue, H.; Shimizu, T.; Kuwano, K.
A novel secreted protease from Pseudomonas aeruginosa activates NF-kappaB through protease-activated receptors
Cell. Microbiol.
10
1491-1504
2008
Pseudomonas aeruginosa
Cheng, M.; Takenaka, S.; Aoki, S.; Murakami, S.; Aoki, K.
Purification and characterization of an eggshell membrane decomposing protease from Pseudomonas aeruginosa strain ME-4
J. Biosci. Bioeng.
107
373-378
2009
Pseudomonas aeruginosa, Pseudomonas aeruginosa ME-4
Mun, J.J.; Tam, C.; Kowbel, D.; Hawgood, S.; Barnett, M.J.; Evans, D.J.; Fleiszig, S.M.
Clearance of Pseudomonas aeruginosa from a healthy ocular surface involves surfactant protein D and is compromised by bacterial elastase in a murine null-infection model
Infect. Immun.
77
2392-2398
2009
Pseudomonas aeruginosa PAO1
Beaufort, N.; Corvazier, E.; Hervieu, A.; Choqueux, C.; Dussiot, M.; Louedec, L.; Cady, A.; de Bentzmann, S.; Michel, J.B.; Pidard, D.
The thermolysin-like metalloproteinase and virulence factor LasB from pathogenic Pseudomonas aeruginosa induces anoikis of human vascular cells
Cell. Microbiol.
13
1149-1167
2011
Pseudomonas aeruginosa
Ghorbel-Bellaaj, O.; Khaled, H.B.; Bayoudh, A.; Younes, I.; Hmidet, N.; Jellouli, K.; Nasri, M.
Pseudomonas aeruginosa A2 elastase: Purification, characterization and biotechnological applications
Int. J. Biol. Macromol.
50
679-686
2012
Pseudomonas aeruginosa, Pseudomonas aeruginosa A2
Andrejko, M.; Mizerska-Dudka, M.
Elastase B of Pseudomonas aeruginosa stimulates the humoral immune response in the greater wax moth, Galleria mellonella
J. Invertebr. Pathol.
107
16-26
2011
Pseudomonas aeruginosa
Wei, G.; Tian, N.; Valery, A.; Zhong, Y.; Schuppan, D.; Helmerhorst, E.
Identification of pseudolysin (lasB) as an aciduric gluten-degrading enzyme with high therapeutic potential for celiac disease
Am. J. Gastroenterol.
110
899-908
2015
Acinetobacter junii, Acinetobacter junii FA10
Falciani, C.; Lozzi, L.; Scali, S.; Brunetti, J.; Bracci, L.; Pini, A.
Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase
Amino Acids
46
1403-1407
2014
Pseudomonas aeruginosa
Han, M.; Wang, X.; Ding, H.; Jin, M.; Yu, L.; Wang, J.; Yu, X.
The role of N-glycosylation sites in the activity, stability, and expression of the recombinant elastase expressed by Pichia pastoris
Enzyme Microb. Technol.
54
32-37
2014
Pseudomonas aeruginosa
Wildeboer, D.; Hill, K.E.; Jeganathan, F.; Williams, D.W.; Riddell, A.D.; Price, P.E.; Thomas, D.W.; Stephens, P.; Abuknesha, R.A.; Price, R.G.
Specific protease activity indicates the degree of Pseudomonas aeruginosa infection in chronic infected wounds
Eur. J. Clin. Microbiol. Infect. Dis.
31
2183-2189
2012
Pseudomonas aeruginosa
Adekoya, O.; Sjoeli, S.; Wuxiuer, Y.; Bilto, I.; Marques, S.; Santos, M.; Nuti, E.; Cercignani, G.; Rossello, A.; Winberg, J.; Sylte, I.
Inhibition of pseudolysin and thermolysin by hydroxamate-based MMP inhibitors
Eur. J. Med. Chem.
89
340-348
2014
Bacillus thermoproteolyticus
Bian, F.; Yue, S.; Peng, Z.; Zhang, X.; Chen, G.; Yu, J.; Xuan, N.; Bi, Y.
A comprehensive alanine-scanning mutagenesis study reveals roles for salt bridges in the structure and activity of Pseudomonas aeruginosa elastase
PLoS ONE
10
e121108
2015
Pseudomonas aeruginosa
Odunuga, O.; Adekoya, O.; Sylte, I.
High-level expression of pseudolysin, the extracellular elastase of Pseudomonas aeruginosa, in Escherichia coli and its purification
Protein Expr. Purif.
113
79-84
2015
Pseudomonas aeruginosa
Yang, J.; Zhao, H.; Ran, L.; Li, C.; Zhang, X.; Su, H.; Shi, M.; Zhou, B.; Chen, X.; Zhang, Y.
Mechanistic insights into elastin degradation by pseudolysin, the major virulence factor of the opportunistic pathogen Pseudomonas aeruginosa
Sci. Rep.
5
9936
2015
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Galdino, A.C.M.; de Oliveira, M.P.; Ramalho, T.C.; de Castro, A.A.; Branquinha, M.H.; Santos, A.L.S.
Anti-virulence strategy against the multidrug-resistant bacterial pathogen Pseudomonas aeruginosa pseudolysin (elastase B) as a potential druggable target
Curr. Protein Pept. Sci.
20
471-487
2019
Pseudomonas aeruginosa
Jose, D.; Mohandas, A.; Bright Singh, I.
Bioprocess technology for LasB protease (elastase) production from Pseudomonas aeruginosa MCCB 123
Indian J. Biotechnol.
17
284-289
2018
Pseudomonas aeruginosa (G1EMI7), Pseudomonas aeruginosa MCCB 123 (G1EMI7)
-
Casilag, F.; Lorenz, A.; Krueger, J.; Klawonn, F.; Weiss, S.; Haeussler, S.
The LasB elastase of Pseudomonas aeruginosa acts in concert with alkaline protease AprA to prevent flagellin-mediated immune recognition
Infect. Immun.
84
162-171
2016
Pseudomonas aeruginosa (Q02RJ6), Pseudomonas aeruginosa UCBPP-PA14 (Q02RJ6)
Said, Z.S.A.M.; Arifi, F.A.M.; Salleh, A.B.; Rahman, R.N.Z.R.A.; Leow, A.T.C.; Latip, W.; Ali, M.S.M.
Unravelling protein -organic solvent interaction of organic solvent tolerant elastase from Pseudomonas aeruginosa strain K crystal structure
Int. J. Biol. Macromol.
127
575-584
2019
Pseudomonas aeruginosa (A7LI11)
Kotb, E.; El-Zawahry, Y.; Saleh, G.
Isolation of a putative virulence agent, cytotoxic serine-elastase, from a newly isolated Pseudomonas aeruginosa ZuhP13
J. Biosci.
44
7
2019
Pseudomonas aeruginosa, Pseudomonas aeruginosa ZuhP13
Smith, K.; Rajendran, R.; Kerr, S.; Lappin, D.F.; Mackay, W.G.; Williams, C.; Ramage, G.
Aspergillus fumigatus enhances elastase production in Pseudomonas aeruginosa co-cultures
Med. Mycol.
53
645-655
2015
Pseudomonas aeruginosa
Li, Y.; Bai, F.; Xia, H.; Zhuang, L.; Xu, H.; Jin, Y.; Zhang, X.; Bai, Y.; Qiao, M.
A novel regulator PA5022 (aefA) is involved in swimming motility, biofilm formation and elastase activity of Pseudomonas aeruginosa
Microbiol. Res.
176
14-20
2015
Pseudomonas aeruginosa, Pseudomonas aeruginosa PA68
van der Plas, M.J.; Bhongir, R.K.; Kjellstroem, S.; Siller, H.; Kasetty, G.; Moergelin, M.; Schmidtchen, A.
Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses
Nat. Commun.
7
11567
2016
Pseudomonas aeruginosa (P14756), Pseudomonas aeruginosa
Shinji, T.; Moe, Y.; Yukihiro, K.; Yoko, Y.; Hitoshi, A.
Characterization of an organic-solvent-stable elastase from Pseudomonas indica and its potential use in eggshell membrane hydrolysis
Proc. Biochem.
85
156-163
2019
Pseudomonas indica (WP_084338031.1), Pseudomonas indica NBRC 103045 (WP_084338031.1)
-
html completed