Reference on EC 3.4.22.53 - calpain-2 and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Shastri, R.; Jagadeesh, G.; Anandaraj, M.P.J.S.
Human placental calcium activated neutral proteinase: Separation and functional characterization of subunits
J. Biosci.
15
427-434
1990
Homo sapiens
-
Rojas, F.J.; Brush, M.; Moretti-Rojas, I.
Calpain-calpastatin: a novel, complete calcium-dependent protease system in human spermatozoa
Mol. Hum. Reprod.
5
520-526
1999
Homo sapiens
Strobl S.; Fernandez-Catalan C.; Braun M.; Huber R.; Masumoto H.; Nakagawa K.; Irie A.; Sorimachi H.; Bourenkow G.; Bartunik H.; Suzuki K.; Bode W.
The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium
Proc. Natl. Acad. Sci. USA
97
588-592
2000
Homo sapiens (P17655), Homo sapiens
Imajoh S.; Aoki K.; Ohno S.; Emori Y.; Kawasaki H.; Sugihara H.; Suzuki K.
Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease
Biochemistry
27
8122-8128
1988
Homo sapiens (P17655)
Hata A.; Ohno S.; Akita Y.; Suzuki K.
Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease
J. Biol. Chem.
264
6404-6411
1989
Homo sapiens (P17655)
Ye Z.; Connor J.R.
cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs
Biochem. Biophys. Res. Commun.
275
223-227
2000
Homo sapiens (P17655)
Strausberg R.L.; Feingold E.A.; Grouse L.H.; Derge J.G.; et al.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Proc. Natl. Acad. Sci. USA
99
16899-16903
2002
Homo sapiens (P17655)
Masumoto, H.; Yoshizawa, T.; Sorimachi, H.; Nishino, T.; Ishiura, S.; Suzuki, K.
Overexpression, purification, and characterization of human m-calpain and its active site mutant, m-C105S-calpain, using a baculovirus expression system
J. Biochem.
124
957-961
1998
Homo sapiens
Dedieu, S.; Mazeres, G.; Dourdin, N.; Cottin, P.; Brustis, J.J.
Transactivation of capn2 by Myogenic Regulatory Factors During Myogenesis
J. Mol. Biol.
326
453-465
2003
Homo sapiens
Veerann, V.; Kaji, T.; Boland, B.; Odrljin, T.; Mohan, P.; Basavarajappa, B.S.; Peterhoff, C.; Cataldo, A.; Rudnicki, A.; Amin, N.; Li, B.S.; Pant, H.C.; Hungund, B.L.; Arancio, O.; Nixon, R.A.
Calpain mediates calcium-induced activation of the Erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: Relevance to Alzheimers disease
Am. J. Pathol.
165
795-805
2004
Homo sapiens
Li, H.; Thompson, V.F.; Goll, D.E.
Effects of autolysis on properties of mu- and m-calpain
Biochim. Biophys. Acta
1691
91-103
2004
Homo sapiens
Carragher, N.O.
Calpain inhibition: a therapeutic strategy targeting multiple disease states
Curr. Pharm. Des.
12
615-638
2006
Homo sapiens (P07384), Homo sapiens
Upla, P.; Marjomaeki, V.; Nissinen, L.; Nylund, C.; Waris, M.; Hyypiae, T.; Heino, J.
Calpain 1 and 2 are required for RNA replication of echovirus 1
J. Virol.
82
1581-1590
2008
Homo sapiens
Miyazaki, T.; Honda, K.; Ohata, H.
Requirement of Ca2+ influx- and phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity
Am. J. Physiol.
293
C1216-C1225
2007
Homo sapiens
Shanmuga Sundaram, J.; Mohana Rao, V.; Meena, A.K.; Anandaraj, M.P.
Altered expression, intracellular distribution and activity of lymphocyte calpain II in Duchenne muscular dystrophy
Clin. Chim. Acta
373
82-87
2006
Homo sapiens
Su, Y.; Cui, Z.; Li, Z.; Bloc, E.R.
Calpain-2 regulation of VEGF-mediated angiogenesis
FASEB J.
20
1443-1451
2006
Homo sapiens
Maehara, H.; Suzuki, K.; Sasaki, T.; Oshita, H.; Wada, E.; Inoue, T.; Shimizu, K.
G1-G2 aggrecan product that can be generated by M-calpain on truncation at Ala709-Ala710 is present abundantly in human articular cartilage
J. Biochem.
141
469-477
2007
Homo sapiens
Sanchez-Sanchez, F.; Martinez-Redondo, F.; Aroca-Aguilar, J.D.; Coca-Prados, M.; Escribano, J.
Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease
J. Biol. Chem.
282
27810-27824
2007
Homo sapiens
Cortesio, C.L.; Chan, K.T.; Perrin, B.J.; Burton, N.O.; Zhang, S.; Zhang, Z.Y.; Huttenlocher, A.
Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
J. Cell Biol.
180
957-971
2008
Homo sapiens
Nuzzi, P.A.; Senetar, M.A.; Huttenlocher, A.
Asymmetric localization of calpain 2 during neutrophil chemotaxis
Mol. Biol. Cell
18
795-805
2007
Homo sapiens
Qiu, K.; Su, Y.; Block, E.R.
Use of recombinant calpain-2 siRNA adenovirus to assess calpain-2 modulation of lung endothelial cell migration and proliferation
Mol. Cell. Biochem.
292
69-78
2006
Homo sapiens
Garnham, C.; Hanna, R.; Chou, J.; Low, K.; Gourlay, K.; Campbell, R.; Beckmann, J.; Davies, P.
Limb-girdle muscular dystrophy type 2A can result from accelerated autoproteolytic inactivation of calpain 3
Biochemistry
48
3457-3467
2009
Homo sapiens (P04632), Rattus norvegicus (Q07009)
Vissing, K.; Overgaard, K.; Nedergaard, A.; Fredsted, A.; Schjerling, P.
Effects of concentric and repeated eccentric exercise on muscle damage and calpain-calpastatin gene expression in human skeletal muscle
Eur. J. Appl. Physiol.
103
323-332
2008
Homo sapiens (P17655), Homo sapiens
Babbin, B.A.; Koch, S.; Bachar, M.; Conti, M.A.; Parkos, C.A.; Adelstein, R.S.; Nusrat, A.; Ivanov, A.I.
Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion
Am. J. Pathol.
174
436-448
2009
Homo sapiens
Wang, H.C.; Huang, Y.S.; Ho, C.C.; Jeng, J.C.; Shih, H.M.
SUMO modification modulates the activity of calpain-2
Biochem. Biophys. Res. Commun.
384
444-449
2009
Homo sapiens
Meng, X.N.; Jin, Y.; Yu, Y.; Bai, J.; Liu, G.Y.; Zhu, J.; Zhao, Y.Z.; Wang, Z.; Chen, F.; Lee, K.Y.; Fu, S.B.
Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion
Br. J. Cancer
101
327-334
2009
Homo sapiens
Barbero, S.; Mielgo, A.; Torres, V.; Teitz, T.; Shields, D.J.; Mikolon, D.; Bogyo, M.; Barila, D.; Lahti, J.M.; Schlaepfer, D.; Stupack, D.G.
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis
Cancer Res.
69
3755-3763
2009
Homo sapiens
Pilop, C.; Aregger, F.; Gorman, R.C.; Brunisholz, R.; Gerrits, B.; Schaffner, T.; Gorman, J.H.; Matyas, G.; Carrel, T.; Frey, B.M.
Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms
Circulation
120
983-991
2009
Homo sapiens
Roumes, H.; Leloup, L.; Dargelos, E.; Brustis, J.J.; Daury, L.; Cottin, P.
Calpains: markers of tumor aggressiveness?
Exp. Cell Res.
316
1587-1599
2010
Homo sapiens
Chen, H.; Libertini, S.J.; Wang, Y.; Kung, H.J.; Ghosh, P.; Mudryj, M.
ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines
J. Biol. Chem.
285
2368-2374
2010
Homo sapiens
Liu, Z.; Wang, S.; Zhou, H.; Yang, Y.; Zhang, M.
Na+/H+ exchanger mediates TNF-alpha-induced hepatocyte apoptosis via the calpain-dependent degradation of Bcl-xL
J. Gastroenterol. Hepatol.
24
879-885
2009
Homo sapiens
Su, L.T.; Chen, H.C.; Gonzalez-Pagan, O.; Overton, J.D.; Xie, J.; Yue, L.; Runnels, L.W.
TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase
J. Mol. Biol.
396
858-869
2010
Homo sapiens
Zadran, S.; Jourdi, H.; Rostamiani, K.; Qin, Q.; Bi, X.; Baudry, M.
Brain-derived neurotrophic factor and epidermal growth factor activate neuronal m-calpain via mitogen-activated protein kinase-dependent phosphorylation
J. Neurosci.
30
1086-1095
2010
Homo sapiens
Ma, H.; Tochigi, A.; Shearer, T.R.; Azuma, M.
Calpain inhibitor SNJ-1945 attenuates events prior to angiogenesis in cultured human retinal endothelial cells
J. Ocul. Pharmacol. Ther.
25
409-414
2009
Homo sapiens
Jang, H.S.; Lal, S.; Greenwood, J.A.
Calpain 2 is required for glioblastoma cell invasion: regulation of matrix metalloproteinase 2
Neurochem. Res.
35
1796-1804
2010
Homo sapiens
Svensson, L.; McDowall, A.; Giles, K.M.; Stanley, P.; Feske, S.; Hogg, N.
Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes
PLoS ONE
5
e15090
2010
Homo sapiens
Prangsaengtong, O.; Senda, K.; Doki, Y.; Park, J.Y.; Jo, M.; Sakurai, H.; Shibahara, N.; Saiki, I.; Koizumi, K.
Calpain 1 and -2 play opposite roles in cord formation of lymphatic endothelial cells via eNOS regulation
Hum. Cell
25
36-44
2012
Homo sapiens
Telechea-Fernandez, M.; Rodriguez-Fernandez, L.; Garcia, C.; Zaragoza, R.; Vina, J.; Cervantes, A.; Garcia-Trevijano, E.R.
New localization and function of calpain-2 in nucleoli of colorectal cancer cells in ribosomal biogenesis effect of KRAS status
Oncotarget
9
9100-9113
2018
Homo sapiens (P17655)
