Reference on EC 3.4.22.43 - cathepsin V and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Brmme, D.; Li, Z.; Barnes, M.; Mehler, E.
Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization
Biochemistry
38
2377-2385
1999
Homo sapiens (O60911), Homo sapiens
Adachi, W.; Kawamoto, S.; Ohno, I.; Nishida, K.; Kinoshita, S.; Matsubara, K.; Okubo, K.
Isolation and characterization of human cathepsin V: a major proteinase in corneal epithelium
Invest. Ophthalmol. Vis. Sci.
39
1789-1796
1998
Homo sapiens
Santamaria, I.; Velasco, G.; Cazorla, M.; Fueyo, A.; Campo, E.; Lopez-Otin, C.
Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas
Cancer Res.
58
1624-1630
1998
Homo sapiens
Somoza, J.R.; Zhan, H.; Bowman, K.K.; Yu, L.; Mortara, K.D.; Palmer, J.T.; Clark, J.M.; McGrath, M.E.
Crystal structure of human cathepsin V
Biochemistry
39
12543-12551
2000
Homo sapiens
Puzer, L.; Cotrin, S.S.; Alves, M.F.; Egborge, T.; Araujo, M.S.; Juliano, M.A.; Juliano, L.; Broemme, D.; Carmona, A.K.
Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L
Arch. Biochem. Biophys.
430
274-283
2004
Homo sapiens
Hagemann, S.; Guenther, T.; Dennemaerker, J.; Lohmueller, T.; Broemme, D.; Schuele, R.; Peters, C.; Reinheckel, T.
The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles
Eur. J. Cell Biol.
83
775-780
2004
Homo sapiens
Broemme, D.
Cathepsin V
Handbook of Proteolytic Enzymes (Barrett, A.J., Rawlings, N.D., Woessner, J.F., eds)
2nd Ed.
1107-1109
2004
Homo sapiens
-
Kenney, M.C.; Chwa, M.; Atilano, S.R.; Tran, A.; Carballo, M.; Saghizadeh, M.; Vasiliou, V.; Adachi, W.; Brown, D.J.
Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder
Invest. Ophthalmol. Vis. Sci.
46
823-832
2005
Homo sapiens
Yasuda, Y.; Li, Z.; Greenbaum, D.; Bogyo, M.; Weber, E.; Broemme, D.
Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages
J. Biol. Chem.
279
36761-36770
2004
Homo sapiens
Cheng, T.; Hitomi, K.; van Vlijmen-Willems, I.M.; de Jongh, G.J.; Yamamoto, K.; Nishi, K.; Watts, C.; Reinheckel, T.; Schalkwijk, J.; Zeeuwen, P.L.
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification
J. Biol. Chem.
281
15893-15899
2006
Homo sapiens
Zeeuwen, P.L.; Ishida-Yamamoto, A.; van Vlijmen-Willems, I.M.; Cheng, T.; Bergers, M.; Iizuka, H.; Schalkwijk, J.
Colocalization of cystatin M/E and cathepsin V in lamellar granules and corneodesmosomes suggests a functional role in epidermal differentiation
J. Invest. Dermatol.
127
120-128
2006
Homo sapiens
Helske, S.; Syvaeranta, S.; Lindstedt, K.A.; Lappalainen, J.; Oeoerni, K.; Maeyraenpaeae, M.I.; Lommi, J.; Turto, H.; Werkkala, K.; Kupari, M.; Kovanen, P.T.
Increased Expression of Elastolytic Cathepsins S, K, and V and Their Inhibitor Cystatin C in Stenotic Aortic Valves
Arterioscler. Thromb. Vasc. Biol.
26
1791-1798
2006
Homo sapiens (O60911)
Burden, R.E.; Snoddy, P.; Jefferies, C.A.; Walker, B.; Scott, C.J.
Inhibition of cathepsin L-like proteases by cathepsin V propeptide
Biol. Chem.
388
541-545
2007
Homo sapiens (O60911)
Puzer, L.; Barros, N.M.; Paschoalin, T.; Hirata, I.Y.; Tanaka, A.S.; Oliveira, M.C.; Broemme, D.; Carmona, A.K.
Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen
Biol. Chem.
389
195-200
2008
Homo sapiens (O60911), Homo sapiens
Ong, P.C.; McGowan, S.; Pearce, M.C.; Irving, J.A.; Kan, W.T.; Grigoryev, S.A.; Turk, B.; Silverman, G.A.; Brix, K.; Bottomley, S.P.; Whisstock, J.C.; Pike, R.N.
DNA accelerates the inhibition of human cathepsin V by serpins
J. Biol. Chem.
282
36980-36986
2007
Homo sapiens (O60911), Homo sapiens
Mihelic, M.; Dobersek, A.; Guncar, G.; Turk, D.
Inhibitory fragment from the p41 form of invariant chain can regulate activity of cysteine cathepsins in antigen presentation
J. Biol. Chem.
283
14453-14460
2008
Homo sapiens
Elie, B.T.; Gocheva, V.; Shree, T.; Dalrymple, S.A.; Holsinger, L.J.; Joyce, J.A.
Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model
Biochimie
92
1618-1624
2010
Homo sapiens
Sevenich, L.; Hagemann, S.; Stoeckle, C.; Tolosa, E.; Peters, C.; Reinheckel, T.
Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice
Biochimie
92
1674-1680
2010
Homo sapiens
Coppini, L.P.; Barros, N.M.; Oliveira, M.; Hirata, I.Y.; Alves, M.F.; Paschoalin, T.; Assis, D.M.; Juliano, M.A.; Puzer, L.; Broemme, D.; Carmona, A.K.
Plasminogen hydrolysis by cathepsin S and identification of derived peptides as selective substrate for cathepsin V and cathepsin L inhibitor
Biol. Chem.
391
561-570
2010
Homo sapiens
Cheng, T.; Tjabringa, G.S.; van Vlijmen-Willems, I.M.; Hitomi, K.; van Erp, P.E.; Schalkwijk, J.; Zeeuwen, P.L.
The cystatin M/E-controlled pathway of skin barrier formation: expression of its key components in psoriasis and atopic dermatitis
Br. J. Dermatol.
161
253-264
2009
Homo sapiens
Renko, M.; Sabotic, J.; Mihelic, M.; Brzin, J.; Kos, J.; Turk, D.
Versatile loops in mycocypins inhibit three protease families
J. Biol. Chem.
285
308-316
2010
Homo sapiens (O60911)
Zeeuwen, P.L.; Cheng, T.; Schalkwijk, J.
The biology of cystatin M/E and its cognate target proteases
J. Invest. Dermatol.
129
1327-1338
2009
Homo sapiens
Wilder, C.L.; Park, K.Y.; Keegan, P.M.; Platt, M.O.
Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues
Arch. Biochem. Biophys.
516
52-57
2011
Homo sapiens
Severino, R.P.; Guido, R.V.; Marques, E.F.; Broemme, D.; da Silva, M.F.; Fernandes, J.B.; Andricopulo, A.D.; Vieira, P.C.
Acridone alkaloids as potent inhibitors of cathepsin V
Bioorg. Med. Chem.
19
1477-1481
2011
Homo sapiens
Piovan, L.; Alves, M.F.; Juliano, L.; Broemme, D.; Cunha, R.L.; Andrade, L.H.
Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins V and S
Bioorg. Med. Chem.
19
2009-2014
2011
Homo sapiens
Skrzypczak, M.; Springwald, A.; Lattrich, C.; Haering, J.; Schueler, S.; Ortmann, O.; Treeck, O.
Expression of cysteine protease cathepsin L is increased in endometrial cancer and correlates with expression of growth regulatory genes
Cancer Invest.
30
398-403
2012
Homo sapiens (O60911), Homo sapiens
Funkelstein, L.; Lu, W.D.; Koch, B.; Mosier, C.; Toneff, T.; Taupenot, L.; O'Connor, D.T.; Reinheckel, T.; Peters, C.; Hook, V.
Human cathepsin V protease participates in production of enkephalin and NPY neuropeptide neurotransmitters
J. Biol. Chem.
287
15232-15241
2012
Homo sapiens (O60911), Homo sapiens
Keegan, P.M.; Wilder, C.L.; Platt, M.O.
Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte-endothelial cell signaling and JNK activation
Mol. Cell. Biochem.
367
65-72
2012
Homo sapiens (O60911), Homo sapiens
Wong, C.H.; Wu, Z.; Yu, Q.
CTSL2 is a pro-apoptotic target of E2F1 and a modulator of histone deacetylase inhibitor and DNA damage-induced apoptosis
Oncogene
33
1249-1257
2014
Homo sapiens (O60911), Homo sapiens
Novinec, M.; Pavsic, M.; Lenarcic, B.
A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli
Protein Expr. Purif.
82
1-5
2012
Homo sapiens (O60911)
Naumnik, W.; Ossolinska, M.; Plonska, I.; Chyczewska, E.; Niklinski, J.
Endostatin and cathepsin-V in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis
Adv. Exp. Med. Biol.
833
55-61
2015
Homo sapiens (O60911), Homo sapiens
Homma, T.; Kageyama, S.; Nishikawa, A.; Nagata, K.
Melanosome degradation in epidermal keratinocytes related to lysosomal protease cathepsin V
Biochem. Biophys. Res. Commun.
500
339-343
2018
Homo sapiens (O60911)
Leng, Y.P.; Ma, Y.S.; Li, X.G.; Chen, R.F.; Zeng, P.Y.; Li, X.H.; Qiu, C.F.; Li, Y.P.; Zhang, Z.; Chen, A.F.
L-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia
Br. J. Pharmacol.
175
1157-1172
2018
Homo sapiens (O60911), Homo sapiens
Huang, K.; Gao, L.; Yang, M.; Wang, J.; Wang, Z.; Wang, L.; Wang, G.; Li, H.
Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin II-induced hypertrophy
Int. J. Biochem. Cell Biol.
89
6-15
2017
Homo sapiens (O60911), Homo sapiens
Mons, E.; Jansen, I.D.C.; Loboda, J.; van Doodewaerd, B.R.; Hermans, J.; Verdoes, M.; van Boeckel, C.A.A.; van Veelen, P.A.; Turk, B.; Turk, D.; Ovaa, H.
The Alkyne moiety as a latent electrophile in irreversible covalent small molecule inhibitors of cathepsin K
J. Am. Chem. Soc.
141
3507-3514
2019
Homo sapiens (P07711)
Pribis, J.P.; Al-Abed, Y.; Yang, H.; Gero, D.; Xu, H.; Montenegro, M.F.; Bauer, E.M.; Kim, S.; Chavan, S.S.; Cai, C.; Li, T.; Szoleczky, P.; Szabo, C.; Tracey, K.J.; Billiar, T.R.
The HIV protease inhibitor saquinavir inhibits HMGB1-driven inflammation by targeting the interaction of cathepsin V with TLR4/MyD88
Mol. Med.
21
749-757
2015
Homo sapiens (O60911), Homo sapiens
