show all | hide all No of entries

Information on EC 3.4.22.42 - cathepsin O

for references in articles please use BRENDA:EC3.4.22.42
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.42 cathepsin O
Specify your search results
Select one or more organisms in this record:
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
procathepsin o, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
The recombinant human enzyme hydrolyses synthetic endopeptidase substrates including Z-Phe-Arg-NHMec and Z-Arg-Arg-NHMec
show the reaction diagram
Cathepsin O is a lysosomal cysteine peptidase of family C1, papain family. The recombinant human enzyme is catalytically active at pH 6.0 and is inhibited by compound E-64. Cathepsin O is ubiquitously expressed in human tissues and the human gene locus is 4q31-32
-
-
-
Select items on the left to see more content.