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Information on EC 3.4.21.83 - Oligopeptidase B
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EC Tree
3.4.21.83 Oligopeptidase BSpecify your search results
Word Map
- 3.4.21.83
- proteases
- leupeptin
-
prolyl
- gingivalis
-
airway
-
chymotrypsin-like
- antipain
- porphyromonas
- aprotinin
- tryptase
-
chloromethyl
-
protease-activated
- chymostatin
- acrosin
-
phenylmethanesulfonyl
- benzamidine
- tlck
-
bapna
- medicine
- proteamaculans
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
La_OpB, oligopeptidase B, OP-Tb, OPB, OPBTc, Opd B, OpdB, Protease II, Proteinase, Escherichia coli alkaline, II, PSP, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
oligopeptidase B
OPB
OPBTc
Opd B
OpdB
Protease II
Proteinase, Escherichia coli alkaline, II
-
-
-
-
PSP
trypsin-like protease
Protease II
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Hydrolysis of -Arg-/-, -Lys-/- bonds in oligopeptides, even when P1' residue is proline
hydrolysis of Arg-+-, Lys-+- bonds in oligopeptides, even when P1' residue is proline, the term-+- depicts the point of cleavage
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hydrolysis of peptide bond
-
-
-
-
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CAS REGISTRY NUMBER
COMMENTARY
57657-67-7
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-aminobenzoyl-ADGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ADGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AEGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AEGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AFGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AFGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGDRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGDR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGERGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGER + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGFRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGFR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRDAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + DAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGREAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + EAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRFAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + FAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGADQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GADQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAEQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAEQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAFQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAFQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGAHQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAHQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAIQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAIQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGALQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GALQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGAMQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAMQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGANQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GANQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAPQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAQQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAQQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGASQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GASQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGATQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GATQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAVQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAVQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGAYQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAYQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGDGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GDGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGEGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GEGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGFGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GFGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGGGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GGGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGHGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GHGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGIGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GIGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGLGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GLGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGMGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GMGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGNGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GNGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGPGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GPGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGQGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GQGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGSGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGRG + Ser-Gly-Gln-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGTGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GTGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGRGVGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GVGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRGYGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GYGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRHAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + HAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRIAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + IAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRLAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + LAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRMAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + MAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRNAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + NAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRPAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + PAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRQAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + QAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRSAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + SAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRTAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + TAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRVAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + VAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGGRYAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + YAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGHRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGHR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGIRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGIR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGKRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGKR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGLRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGLR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGMRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGMR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGNRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGNR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGPRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGPR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGQRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGQR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGRRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGRR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGSRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGSR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGTRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGTR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGVRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGVR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AGYRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGYR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AHGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AHGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AIGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AIGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-ALGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ALGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AMGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AMGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-ANGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ANGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-APGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-APGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AQGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AQGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-ASGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ASGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-ATGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ATGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AVGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AVGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-AYGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AYGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-Phe-Arg + Ser-Ser-Arg-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-GFSPFRSSRIGIKEEQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-GFSPFR + SSRIGIKEEQ-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-LGMISLMKRPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-LGMISLMK + Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-MISLMKRPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-MISLMK + Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-RPPGFSPFRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-RPPGFSPFR + Gln-N-(2,4-dinitrophenyl)ethylenediamine
2-aminobenzoyl-RPPGFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-RPPGFSPFR + Ser-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
3-(2-furyl)acryloyl-Tyr-Lys-Arg + H2O
3-(2-furyl)acryloyl-Tyr-Lys + Arg
-
-
-
?
acetyl-L-Leu-L-Leu-L-Arg-4-nitroanilide + H2O
acetyl-L-Leu-L-Leu-L-Arg + 4-nitroaniline
-
-
-
-
?
acetyl-L-Leu-L-Lys-L-Arg-4-nitroanilide + H2O
acetyl-L-Leu-L-Lys-L-Arg + 4-nitroaniline
-
-
-
-
?
acetyl-Leu-Leu-Arg-4-nitroanilide + H2O
acetyl-Leu-Leu-Arg + 4-nitroaniline
-
-
-
-
?
adrenocorticotropic hormone + H2O
SYSMEHFR + WGK + WGKPVGK + VYP
-
-
-
-
?
benzoyl-Gly-Gly-L-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Gly-Gly-L-Arg + 7-amino-4-methylcoumarin
C9EF60
-
-
-
?
benzoyl-Gly-L-Pro-L-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Gly-L-Pro-L-Arg + 7-amino-4-methylcoumarin
C9EF60
-
-
-
?
benzoyl-L-Pro-L-Phe-L-Arg-4-nitroanilide + H2O
benzoyl-L-Pro-L-Phe-L-Arg + 4-nitroaniline
-
-
-
-
?
Benzoyl-Lys 2-naphthylamide + H2O
Benzoyl-Lys + 2-naphthylamine
-
-
-
-
-
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide + H2O
?
-
-
?
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O
?
-
-
?
benzyloxycarbonyl-Arg-Arg-4-methylcoumaryl 7-amide + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
benzyloxycarbonyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Gly-Arg-4-methylcoumarin 7-amide + H2O
?
-
-
?
benzyloxycarbonyl-Gly-Gly-Arg-4-methylcoumarin 7-amide + H2O
?
-
-
?
benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Gly-Gly-Arg + 7-amino-4-methylcoumarin
benzyloxycarbonyl-Gly-L-Arg-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Gly-L-Arg-L-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Gly-L-Pro-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Gly-L-Pro-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-L-Leu-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-L-Leu-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
benzyloxycarbonyl-L-Val-L-Val-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-L-Val-L-Val-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
benzyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Leu-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Lys-4-methylcoumarin 7-amide + H2O
?
-
-
?
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O
?
-
-
?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
benzyloxycarbonyl-Phe-Arg-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
benzyloxycarbonyl-Val-Arg-4-methylcoumarin 7-amide + H2O
?
-
-
?
Boc-Gly-Arg-Arg-4-methylcoumarin 7-amide + H2O
Boc-Gly-Arg-Arg + 7-amino-4-methylcoumarin
-
-
?
Boc-Gly-Lys-Arg-4-methylcoumarin 7-amide + H2O
Boc-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
-
?
CBZ-L-Arg-L-Arg-7-amido-4-methylcoumarin + H2O
CBZ-L-Arg-L-Arg + 7-amino-4-methylcoumarin
-
weak substrate
-
-
?
DL-Val-Leu-Arg-paranitroanilide + H2O
DL-Val-Leu-Arg + p-nitroaniline
-
-
-
-
?
Glucagon + H2O
?
-
wild type enzyme cleaves Lys12-Tyr13, Arg17-Arg18, and Arg18-Ala19 bonds of glucagon
-
-
?
histone + H2O
?
human histones H1, H2A, H3 and H4, restricted proteolysis
-
?
L-pGlu-Gly-L-Arg-7-amido-4-methylcoumarin + H2O
L-pGlu-Gly-L-Arg + 7-amino-4-methylcoumarin
-
low hydrolytic rate
-
-
?
L-pGlu-L-Arg-L-Thr-L-Lys-L-Arg-7-amido-4-methylcoumarin + H2O
L-pGlu-L-Arg-L-Thr-L-Lys-L-Arg + 7-amino-4-methylcoumarin
-
low hydrolytic rate
-
-
?
L-Pro-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
L-Pro-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
N-Benzoyl-DL-Arg 4-nitroanilide + H2O
N-Benzoyl-DL-Arg + 4-nitroaniline
-
-
-
-
-
N-Benzyloxycarbonyl-Gly 4-nitrophenyl ester + H2O
N-Benzyloxycarbonyl-Gly + 4-nitrophenol
-
weak
-
-
-
N-benzyloxycarbonyl-Gly-Gly-L-Arg-7-amido-4-methylcoumarin + H2O
N-benzyloxycarbonyl-Gly-Gly-L-Arg + 7-amino-4-methylcoumarin
-
-
-
?
N-benzyloxycarbonyl-L-Arg-L-Arg-7-amido-4-methylcoumarin + H2O
N-benzyloxycarbonyl-L-Arg-L-Arg + 7-amino-4-methylcoumarin
-
-
-
?
N-benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
N-benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
-
-
?
N-Benzyloxycarbonyl-Lys benzyl ester + H2O
N-Benzyloxycarbonyl-Lys + benzol
-
-
-
-
-
N-Carbobenzoxy-L-Lys 4-nitrophenyl ester + H2O
N-Carbobenzoxy-L-Lys + 4-nitrophenol
-
-
-
-
-
N-tosyl-Gly-Pro-Arg-paranitroanilide + H2O
N-tosyl-Gly-Pro-Arg + p-nitroaniline
-
-
-
-
?
Nalpha-benzoyl-Arg-7-amido-4-methylcoumarin + H2O
?
-
68% of the activity with carbobenzoxy-Arg-Arg-4-methylcoumaryl-7-amide
-
-
?
Nalpha-benzoyl-DL-Arg-4-nitroanilide + H2O
Nalpha-benzoyl-DL-Arg + 4-nitroaniline
-
-
-
-
?
Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O
Nalpha-benzoyl-DL-arginine + 4-nitroaniline
Nalpha-benzyloxycarbonyl-L-Ala-L-Ala-L-Arg-4-nitroanilide + H2O
Nalpha-benzyloxycarbonyl-L-Ala-L-Ala-L-Arg + 4-nitroaniline
-
poor substrate
-
-
?
Nalpha-benzyloxycarbonyl-L-lysine thiobenzyl ester + H2O
Nalpha-benzyloxycarbonyl-L-lysine + phenylmethanethiol
-
-
-
-
?
Nalpha-benzyloxycarbonyl-L-Phe-L-Arg-4-nitroanilide + H2O
Nalpha-benzyloxycarbonyl-L-Phe-L-Arg + 4-nitroaniline
-
-
-
-
?
RRRPRPPRLPRPRPR + 2 H2O
L-Arg-L-Arg + RPRPPR + LPRPRPR
-
proline-rich peptide Bac(1-16)
-
-
?
RRRPRPPYLPRPRPPPFF + H2O
L-Arg-L-Arg + RPRPPYLPRPRPPPFF
-
proline-rich peptide PR-39(1-18)
-
-
?
succinyl-Gly-L-Pro-L-Lys-4-nitroanilide + H2O
succinyl-Gly-L-Pro-L-Lys + 4-nitroaniline
-
poor substrate
-
-
?
succinyl-L-Ala-L-Ala-L-Pro-L-Lys-4-nitroanilide + H2O
succinyl-L-Ala-L-Ala-L-Pro-L-Lys + 4-nitroaniline
-
-
-
-
?
succinyl-L-AlaL-Ala-L-Pro-L-Arg-4-nitroanilide + H2O
succinyl-L-Ala-L-Ala-L-Pro-L-Arg + 4-nitroaniline
-
-
-
-
?
t-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Ala-Gly-Pro-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Arg-Val-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Ala-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Gln-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Arg-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Gln-Gly-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Gly-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Glu-Lys-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Glu-Lys-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Arg-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Lys-Arg + 7-amino-4-methylcoumarin
t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Val-Leu-Arg + 7-amino-4-methylcoumarin
tert-butoxycarbonyl-L-Val-L-Leu-L-Lys-7-amido-4-methylcoumarin + H2O
tert-butoxycarbonyl-L-Val-L-Leu-L-Lys + 7-amino-4-methylcoumarin
-
best substrate, the hydrolytic activity is observed only in the presence of NaCl and the thiol-reacting reagents dithiothreitol, reduced glutathione, and oxidized glutathione at pH 8.5 (50 mM Tris-HCl)
-
-
?
tert-butyloxycarbonyl-Ala-Arg-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Glu-Lys-Lys-7-amido-4-methylcoumarin + H2O
?
-
specific substrate for Escherichia coli oligopeptidase B, 20% of the activity with carbobenzoxy-Arg-Arg-4-methylcoumaryl-7-amide
-
-
?
tert-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Leu-Arg-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Leu-Gly-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Val-Gly-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tert-butyloxycarbonyl-Val-Pro-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
tosyl-Gly-L-Pro-L-Arg-7-amido-4-methylcoumarin + H2O
tosyl-Gly-L-Pro-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
tosyl-Gly-L-Pro-L-Lys-7-amido-4-methylcoumarin + H2O
tosyl-Gly-L-Pro-L-Lys + 7-amino-4-methylcoumarin
-
-
-
-
?
2-aminobenzoyl-ADGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ADGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ADGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ADGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AEGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AEGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AEGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AEGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AFGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AFGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AFGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AFGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGDRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGDR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGDRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGDR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGERGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGER + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGERGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGER + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGFRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGFR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGFRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGFR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRDAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + DAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRDAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + DAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGREAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + EAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGREAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + EAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRFAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + FAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRFAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + FAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAIQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAIQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAIQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAIQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGALQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GALQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGALQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GALQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AGGRGAQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AGGRGAVQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAVQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGAVQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GAVQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGDGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GDGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGDGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GDGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGEGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GEGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGEGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GEGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGFGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GFGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGFGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GFGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGGGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GGGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGGGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GGGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGHGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GHGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGHGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GHGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGIGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GIGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGIGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GIGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGLGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GLGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGLGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GLGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGMGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GMGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGMGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GMGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGNGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GNGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGNGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GNGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGPGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GPGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGPGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GPGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGQGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GQGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGQGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GQGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGSGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGRG + Ser-Gly-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGSGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGRG + Ser-Gly-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGTGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GTGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
-
-
-
?
2-aminobenzoyl-AGGRGTGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GTGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
-
-
-
?
2-aminobenzoyl-AGGRGVGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GVGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGVGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GVGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGYGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GYGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRGYGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + GYGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRHAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + HAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRHAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + HAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRIAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + IAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRIAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + IAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRLAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + LAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRLAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + LAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRMAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + MAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRMAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + MAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRNAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + NAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRNAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + NAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRPAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + PAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRPAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + PAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRQAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + QAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRQAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + QAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRSAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + SAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRSAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + SAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRTAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + TAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRTAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + TAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRVAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + VAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRVAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + VAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRYAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + YAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGGRYAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGGR + YAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGHRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGHR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGHRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGHR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGIRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGIR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGIRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGIR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGKRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGKR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGKRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGKR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGLRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGLR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGLRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGLR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGMRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGMR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGMRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGMR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGNRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGNR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGNRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGNR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGPRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGPR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGPRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGPR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGQRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGQR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGQRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGQR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGRRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGRR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGRRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGRR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGRRRAQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AGRRRAQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AGSRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGSR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGSRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGSR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGTRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGTR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGTRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGTR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGVRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGVR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGVRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGVR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGYRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGYR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AGYRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AGYR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AHGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AHGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AHGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AHGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AHKRYSHQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AHKRYSHQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AIGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AIGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AIGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AIGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ALGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ALGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ALGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ALGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AMGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AMGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AMGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AMGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AMRRTISQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-AMRRTISQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-ANGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ANGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ANGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ANGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-APGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-APGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-APGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-APGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AQGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AQGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AQGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AQGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ASGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ASGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ASGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ASGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ATGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ATGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-ATGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-ATGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AVGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AVGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AVGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AVGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AYGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AYGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-AYGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-AYGR + GAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-FRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-FRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-Phe-Arg + Ser-Ser-Arg-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-FRSSR-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-Phe-Arg + Ser-Ser-Arg-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-GFSPFRSSRIGIKEEQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-GFSPFR + SSRIGIKEEQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-GFSPFRSSRIGIKEEQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-GFSPFR + SSRIGIKEEQ-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-GFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
?
-
-
-
?
2-aminobenzoyl-LGMISLMKRPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-LGMISLMK + Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-LGMISLMKRPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-LGMISLMK + Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-MISLMKRPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-MISLMK + Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-MISLMKRPQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-MISLMK + Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-RPPGFSPFRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-RPPGFSPFR + Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-RPPGFSPFRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-RPPGFSPFR + Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-RPPGFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-RPPGFSPFR + Ser-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
2-aminobenzoyl-RPPGFSPFRSSRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-RPPGFSPFR + Ser-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
-
-
-
?
Atrial natriuretic factor + H2O
?
cleavage at four sites: Arg3-Arg4, Arg4-/-Ser5, Arg11-/-Ile12, and Arg27-Tyr28, thereby abrogating smooth muscle relaxant and prohypotensive properties of atrial natriuretic factor. The in vitro half-life of atrial natriuretic factor in rat plasma is reduced 300fold in plasma from Trypanosoma evansi infected rodents, which contain high levels of OpdB activity. Oligopeptidase B plays a role in peptide hormone dysregulation in trypanosomiasis, specifically in generating the depressed plasma levels of atrial natriuretic factor in mammals infected with trypanosoma evansi
-
-
?
Atrial natriuretic factor + H2O
?
cleavage at four sites: Arg3-Arg4, Arg4-/-Ser5, Arg11-/-Ile12, and Arg27-Tyr28, thereby abrogating smooth muscle relaxant and prohypotensive properties of atrial natriuretic factor
-
-
?
benzoyl-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzoyl-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzoyl-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
benzoyl-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzoyl-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzoyl-L-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-L-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzoyl-L-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Gly-Gly-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Gly-Gly-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
benzyloxycarbonyl-Leu-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Insulin B-chain + H2O
?
-
cleaves the carboxymethylated B-chain of insulin at the Arg22-Gly23 bond, but after prolonged periods of incubation it is also able to cleave the Tyr16-Leu17 bond
-
-
-
Insulin B-chain + H2O
?
-
cleavage at the carboxyl sides of Arg and Lys residues
-
-
-
Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O
Nalpha-benzoyl-DL-arginine + 4-nitroaniline
-
-
-
-
?
Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O
Nalpha-benzoyl-DL-arginine + 4-nitroaniline
-
-
-
?
Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O
Nalpha-benzoyl-DL-arginine + 4-nitroaniline
-
-
-
?
Nalpha-benzoyl-L-Arg 2-naphthylamide + H2O
Nalpha-benzoyl-L-Arg + 2-naphthylamine
-
-
-
-
-
Nalpha-benzoyl-L-Arg 2-naphthylamide + H2O
Nalpha-benzoyl-L-Arg + 2-naphthylamine
-
-
-
?
Nalpha-benzoyl-L-Arg 2-naphthylamide + H2O
Nalpha-benzoyl-L-Arg + 2-naphthylamine
-
-
-
?
t-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Ala-Gly-Pro-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Ala-Gly-Pro-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Ala-Gly-Pro-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Ala-Gly-Pro-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Arg-Val-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Arg-Val-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Arg-Val-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Arg-Val-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Arg-Val-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Ala-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Ala-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Ala-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Ala-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gln-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Gln-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gln-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Arg-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Gln-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gln-Gly-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Gly-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Gln-Gly-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Gly-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gln-Gly-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Gly-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Gln-Gly-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gln-Gly-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Glu-Lys-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Glu-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Glu-Lys-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Glu-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Glu-Lys-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Glu-Lys-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Glu-Lys-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Glu-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Arg-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Lys-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Val-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Val-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
?
t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Val-Leu-Arg + 7-amino-4-methylcoumarin
K0J8D4
-
-
-
?
t-butyloxycarbonyl-Val-Leu-Lys-7-amido-4-methylcoumarin + H2O
t-butyloxycarbonyl-Val-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
?
additional information
?
-
-
hydrolyzes peptides with dibasic sites much faster than monobasic substrates, hydrolyzes the peptide bond at lysine and arginine residues
-
?
additional information
?
-
-
specific for substrates with a pair of basic residues at positions P1 and P2
-
?
additional information
?
-
OpdB does not hydrolyse protein substrates with the exception of nominal digestion of the endogenous Escherichia coli enzymes aspartokinase L-homoserine dehydrogenase and aspartokinase III
-
-
-
additional information
?
-
-
oligopeptidase B can efficiently hydrolyze in vitro cationic antimicrobial peptides up to 30 residues in length, even though they contained several prolines, shortening them to inactive fragments. Two consecutive basic residues are a preferred cleavage site for the peptidase. In the case of a single basic residue, there is no cleavage if proline residues are present in the P1 and P2 positions
-
-
-
additional information
?
-
C9EF60
OPB has a strong preference for lysine or arginine residues at P1. OPB can accommodate several amino acids in the P2–P4 positions, with a preference for glycine in P2, serine, glycine, alanine, asparagine, proline, and threonine in P3, and proline in P4. Bulky hydrophobic groups, such as tyrosine, phenylalanine, and tryptophan, are least preferred
-
-
-
additional information
?
-
-
no substrate: N-benzyloxycarbonyl-Gly-L-Pro-7-amido-4-methylcoumarin
-
-
-
additional information
?
-
no substrate: N-benzyloxycarbonyl-Gly-L-Pro-7-amido-4-methylcoumarin
-
-
-
additional information
?
-
exhibits amidolytic activity exclusively against substrates with basic residues in P1, no activity is observed against H-Arg-4-methylcoumarin 7-amide, H-Leu-4-methylcoumarin 7-amide, H-Lys-4-methylcoumarin 7-amide, benzyloxycarbonyl-Leu-Leu-Glu-beta-nitroanilide, benzyloxycarbonyl-Gly-Gly-Leu-p-nitroanilide, benzyloxycarbonyl-Ala-Ala-Phe-4-methylcoumarin 7-amide, Suc-Ile-Ala-4-methylcoumarin 7-amide, Suc-Gly-Pro-4-methylcoumarin 7-amide, Ac-Tyr-Val-Ala-Asp-p-nitroanilide, Suc-Ala-Ala-Pro-Phe-4-methylcoumarin 7-amide
-
?
additional information
?
-
-
no hydrolytic activity against the aminopeptidase substrates (4-nitroanilide derivatives of amino acids) and FITC-casein, substrates containing Pro at Xaa positions in the FRETS library are not hydrolyzed
-
-
-
additional information
?
-
-
no hydrolysis of 2-aminobenzoyl acid-LGMISLMKRPPGFSPFRSSRI-NH2-N-(2,4-dinitrophenyl)ethylenediamine
-
?
additional information
?
-
-
the enzyme may be associated with Chagas disease pathogenesis nb yhydrolyzing host proteins and inducing host immune responses
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
Atrial natriuretic factor + H2O
?
Q6QDP1
cleavage at four sites: Arg3-Arg4, Arg4-/-Ser5, Arg11-/-Ile12, and Arg27-Tyr28, thereby abrogating smooth muscle relaxant and prohypotensive properties of atrial natriuretic factor. The in vitro half-life of atrial natriuretic factor in rat plasma is reduced 300fold in plasma from Trypanosoma evansi infected rodents, which contain high levels of OpdB activity. Oligopeptidase B plays a role in peptide hormone dysregulation in trypanosomiasis, specifically in generating the depressed plasma levels of atrial natriuretic factor in mammals infected with trypanosoma evansi
-
-
?
additional information
?
-
-
the enzyme may be associated with Chagas disease pathogenesis nb yhydrolyzing host proteins and inducing host immune responses
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Ca2+
Ca2+
-
stimulates amidase and proteolytic activities, maximal activation of 25% at concentrations above 25 mM
Ca2+
-
in presence of Ca2+, efficiency of hydrolysis of substrates with positively charged P2 residues decreases by an order of magnitude due to the worsening in the substrate binding. In the presence of 50 mM Ca2+, no substrate inhibition is observed in the case of acetyl-L-Leu-L-Lys-L-Arg-4-nitroanilide, and the effect was less pronounced for other substrates
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
4-(2-aminoethyl)benzenesulfonylfluoride
Q382P7
non-peptide irreversible serine-peptidase inhibitor
benzoyl-Arg-4-nitroanilide
-
enzyme is inhibited by high concentrations of substrate
bovine basic pancreatic trypsin inhibitor
-
substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, competitive
-
diisopropylfluorophosphate
Q382P7
non-peptide irreversible serine-peptidase inhibitor
m-phenanthroline
-
substrates Nalpha-benzoyl-DL-Arg-4-nitroanilide, acetyl-Leu-Leu-Arg-4-nitroanilide, anticompetitive
methanol
-
incubation in 20% (v/v) methanol (10-20 h, 4°C) results in partial decomposition of the high molecular weight PSP-GroEL complex with precipitation of denatured chaperonin and a small (no more than 10%) loss of PSP activity
NaCl
-
loss of almost 50 and 70% of its activity in the presence of 0.2 and 1.0 M NaCl, respectively. Presence of NaCl does not disrupt the dimeric structure
NEM
-
Cys256 is the reactive cysteine residue that mediates OpdB inhibition. Cys256 adducts occlude the P1 substrate-binding site, preventing substrate binding
o-phenanthroline
-
substrates Nalpha-benzoyl-DL-Arg-4-nitroanilide, acetyl-Leu-Leu-Arg-4-nitroanilide, anticompetitive
p-chloromercuribenzoate
Q382P7
non-peptide irreversible serine-peptidase inhibitor
peptidyl phosphonate alpha-aminoalkyl diphenyl ester
Q382P7
irreversible peptidyl inhibitors
protamines
-
protamines, basic 30-32 residue peptides that are rich in Arg residues, are potent inhibitors of OpdB
-
tert-butoxycarbonyl-L-Val-L-Leu-L-Lys-7-amido-4-methylcoumarin
-
in the case of added dithiothreitol, reduced glutathione, or oxidized glutathione, a high concentration of the substrate tert-butoxycarbonyl-L-Val-L-Leu-L-Lys-7-amido-4-methylcoumarin inhibits the enzyme activity. By contrast, addition of 1 M NaCl to either dithiothreitol, reduced glutathione, or oxidized glutathione or 1 M NaCl alone prevents substrate inhibition
trans-4-guanidinomethylcyclohexanecarboxylic acid 4-tert-butylphenyl ester
-
IC50: about 0.01 mM. Oligopeptidase B is much more sensitive than oligopeptidase B
ZnCl2
-
substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, noncompetitive
3,4-dichloroisocoumarin
Q382P7
non-peptide irreversible serine-peptidase inhibitor
4-(2-aminoethyl)benzenesulfonyl fluoride
irreversible inhibition
4-(2-aminoethyl)benzenesulfonyl fluoride
-
OpdB activity toward tert-butoxycarbonyl-L-Val-L-Leu-L-Lys-7-amido-4-methylcoumarin hydrolysis is inhibited completely by 4 mM pefbloc SC
antipain
-
OpdB activity toward tert-butoxycarbonyl-L-Val-L-Leu-L-Lys-7-amido-4-methylcoumarin hydrolysis is inhibited completely by 0.3 mM antipain
leupeptin
-
OpdB activity toward tert-butoxycarbonyl-L-Val-L-Leu-L-Lys-7-amido-4-methylcoumarin hydrolysis is inhibited completely by 0.05 mM leupeptin
additional information
-
1,10-phenanthroline; EDTA; not: chelating agents; PMSF; several natural trypsin inhibitors; sulfhydryl agents
-
additional information
-
no inhibition by N-ethylmaleimide and iodoacetic acid. This is consistent with the absence of a cysteine residue at position 256 which is replaced by His
-
additional information
no inhibition of wild-type enzyme with iodoacetamide, iodoacetate, N-ethylmaleimide, EDTA, EGTA, bestatin,amastatin, arphamenine A, elastinal, dynorphin A or dynorphin B
-
additional information
-
OpdB is not inhibited by E-64 (0.03 mM), pepstain (0.04 mM), EDTA (1 mM), chimostatin (0.2 mM), and phosphoramidon (0.4 mM)
-
additional information
-
reducing reagent such as dithiothreitol has no effect on the inactivation of wild type and mutant OPBs by heat and urea treatment
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
NaCl
-
enzymatic activity is markedly enhanced by high NaCl concentration, NaCl affects the P1 preference of OpdB synergistically in a substrate-dependent manner
oxidized glutathione
-
oxidized glutathione enhances OpdB activity and affects the P1 preference of OpdB synergistically in a substrate-dependent manner
reduced glutathione
-
enzymatic activity is markedly enhanced by reduced glutathione at submillimolar level which affects the P1 preference of OpdB synergistically in a substrate-dependent manner
dithiothreitol
-
enzymatic activity is markedly enhanced by dithiothreitol at submillimolar level, which affects the P1 preference of OpdB synergistically in a substrate-dependent manner
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.0036
2-aminobenzoyl-ADGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.039
2-aminobenzoyl-AEGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.013
2-aminobenzoyl-AGDRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0033
2-aminobenzoyl-AGERGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0057
2-aminobenzoyl-AGGRGADQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.021
2-aminobenzoyl-AGGRGAEQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0063
2-aminobenzoyl-AGHRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0083
2-aminobenzoyl-ANGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.00308
benzoyl-Gly-Gly-L-Arg-7-amido-4-methylcoumarin
C9EF60
pH 8.0, 25°C
0.00776
benzoyl-Gly-L-Pro-L-Arg-7-amido-4-methylcoumarin
C9EF60
pH 8.0, 25°C
0.0002
benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme; pH 8.0, 37°C, recombinant enzyme
0.0034
benzyloxycarbonyl-Gly-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C
0.0023
benzyloxycarbonyl-Gly-Gly-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C
0.0012
benzyloxycarbonyl-Gly-L-Arg-L-Arg-7-amido-4-methylcoumarin
21°C, pH not specified in the publication
0.0054
benzyloxycarbonyl-Lys-4-methylcoumarin 7-amide
pH 8.0, 37°C
0.0026
benzyloxycarbonyl-Val-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C
0.0038
N-benzyloxycarbonyl-Gly-Gly-L-Arg-7-amido-4-methylcoumarin
21°C, pH not specified in the publication
0.00093
N-benzyloxycarbonyl-L-Arg-L-Arg-7-amido-4-methylcoumarin
21°C, pH not specified in the publication
0.0031
N-benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin
21°C, pH not specified in the publication
2.2
succinyl-L-Ala-L-Ala-L-Pro-L-Lys-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.0032
2-aminobenzoyl-AFGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0034
2-aminobenzoyl-AFGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0024
2-aminobenzoyl-AGFRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0031
2-aminobenzoyl-AGFRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0015
2-aminobenzoyl-AGGRDAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0045
2-aminobenzoyl-AGGRDAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0014
2-aminobenzoyl-AGGREAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0065
2-aminobenzoyl-AGGREAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0003
2-aminobenzoyl-AGGRFAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0027
2-aminobenzoyl-AGGRFAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0062
2-aminobenzoyl-AGGRGAFQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0097
2-aminobenzoyl-AGGRGAFQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0011
2-aminobenzoyl-AGGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0072
2-aminobenzoyl-AGGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0034
2-aminobenzoyl-AGGRGAHQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0037
2-aminobenzoyl-AGGRGAHQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.011
2-aminobenzoyl-AGGRGAIQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.031
2-aminobenzoyl-AGGRGAIQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0073
2-aminobenzoyl-AGGRGALQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.012
2-aminobenzoyl-AGGRGALQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.003
2-aminobenzoyl-AGGRGAMQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0031
2-aminobenzoyl-AGGRGAMQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0059
2-aminobenzoyl-AGGRGANQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.018
2-aminobenzoyl-AGGRGANQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0011
2-aminobenzoyl-AGGRGAPQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0028
2-aminobenzoyl-AGGRGAPQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0072
2-aminobenzoyl-AGGRGAPQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.013
2-aminobenzoyl-AGGRGAPQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0048
2-aminobenzoyl-AGGRGAQQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0088
2-aminobenzoyl-AGGRGAQQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.002
2-aminobenzoyl-AGGRGASQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.012
2-aminobenzoyl-AGGRGASQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.006
2-aminobenzoyl-AGGRGATQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.027
2-aminobenzoyl-AGGRGATQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0091
2-aminobenzoyl-AGGRGAVQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.021
2-aminobenzoyl-AGGRGAVQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0057
2-aminobenzoyl-AGGRGAYQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.011
2-aminobenzoyl-AGGRGAYQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.008
2-aminobenzoyl-AGGRGDGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.012
2-aminobenzoyl-AGGRGDGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.01
2-aminobenzoyl-AGGRGEGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.138
2-aminobenzoyl-AGGRGEGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0021
2-aminobenzoyl-AGGRGFGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.012
2-aminobenzoyl-AGGRGFGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0062
2-aminobenzoyl-AGGRGGGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.014
2-aminobenzoyl-AGGRGGGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0028
2-aminobenzoyl-AGGRGHGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0033
2-aminobenzoyl-AGGRGHGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0032
2-aminobenzoyl-AGGRGIGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.011
2-aminobenzoyl-AGGRGIGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0052
2-aminobenzoyl-AGGRGLGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.024
2-aminobenzoyl-AGGRGLGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.003
2-aminobenzoyl-AGGRGMGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.02
2-aminobenzoyl-AGGRGMGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0046
2-aminobenzoyl-AGGRGNGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0092
2-aminobenzoyl-AGGRGNGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0012
2-aminobenzoyl-AGGRGPGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0098
2-aminobenzoyl-AGGRGPGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0023
2-aminobenzoyl-AGGRGQGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.01
2-aminobenzoyl-AGGRGQGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0032
2-aminobenzoyl-AGGRGSGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0037
2-aminobenzoyl-AGGRGSGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0058
2-aminobenzoyl-AGGRGTGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.013
2-aminobenzoyl-AGGRGTGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.02
2-aminobenzoyl-AGGRGVGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.031
2-aminobenzoyl-AGGRGVGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0039
2-aminobenzoyl-AGGRGYGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0044
2-aminobenzoyl-AGGRGYGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0005
2-aminobenzoyl-AGGRHAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0017
2-aminobenzoyl-AGGRHAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0003
2-aminobenzoyl-AGGRIAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0005
2-aminobenzoyl-AGGRIAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0006
2-aminobenzoyl-AGGRLAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0013
2-aminobenzoyl-AGGRLAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0069
2-aminobenzoyl-AGGRMAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0083
2-aminobenzoyl-AGGRMAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0004
2-aminobenzoyl-AGGRNAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0013
2-aminobenzoyl-AGGRNAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0005
2-aminobenzoyl-AGGRQAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0007
2-aminobenzoyl-AGGRQAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0005
2-aminobenzoyl-AGGRSAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0012
2-aminobenzoyl-AGGRSAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0003
2-aminobenzoyl-AGGRTAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0009
2-aminobenzoyl-AGGRTAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0001
2-aminobenzoyl-AGGRVAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0014
2-aminobenzoyl-AGGRVAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0004
2-aminobenzoyl-AGGRYAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0006
2-aminobenzoyl-AGGRYAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0012
2-aminobenzoyl-AGIRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.01
2-aminobenzoyl-AGIRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0018
2-aminobenzoyl-AGKRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0048
2-aminobenzoyl-AGKRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0019
2-aminobenzoyl-AGLRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0077
2-aminobenzoyl-AGLRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0025
2-aminobenzoyl-AGMRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0029
2-aminobenzoyl-AGMRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.004
2-aminobenzoyl-AGNRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.023
2-aminobenzoyl-AGNRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0082
2-aminobenzoyl-AGPRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.016
2-aminobenzoyl-AGPRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0014
2-aminobenzoyl-AGQRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0059
2-aminobenzoyl-AGQRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0004
2-aminobenzoyl-AGSRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0006
2-aminobenzoyl-AGSRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0019
2-aminobenzoyl-AGTRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0075
2-aminobenzoyl-AGTRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0014
2-aminobenzoyl-AGVRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0039
2-aminobenzoyl-AGVRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0077
2-aminobenzoyl-AGYRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.014
2-aminobenzoyl-AGYRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0032
2-aminobenzoyl-AHGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0035
2-aminobenzoyl-AHGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.002
2-aminobenzoyl-AIGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0044
2-aminobenzoyl-AIGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0013
2-aminobenzoyl-ALGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0026
2-aminobenzoyl-ALGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0009
2-aminobenzoyl-AMGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH8.0, 37°C
0.0059
2-aminobenzoyl-AMGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.001
2-aminobenzoyl-APGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH8.0, 37°C
0.0019
2-aminobenzoyl-APGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0019
2-aminobenzoyl-AQGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0024
2-aminobenzoyl-AQGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0023
2-aminobenzoyl-ASGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0074
2-aminobenzoyl-ASGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0018
2-aminobenzoyl-ATGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0082
2-aminobenzoyl-ATGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0026
2-aminobenzoyl-AVGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.013
2-aminobenzoyl-AVGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0018
2-aminobenzoyl-AYGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.003
2-aminobenzoyl-AYGRGAGQ-N-(2,4-dinitrophenyl)ethylenediamine
-
pH 8.0, 37°C
0.0019
3-(2-furyl)acryloyl-Tyr-Lys-Arg
pH 8.0, 37°C, recombinant enzyme
0.457
acetyl-L-Leu-L-Leu-L-Arg-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.265
acetyl-L-Leu-L-Lys-L-Arg-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.0044
Ala-Phe-Lys-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.005
Ala-Phe-Lys-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.048
Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.00268
benzoyl-Arg-7-amido-4-methylcoumarin
-
wild-type, pH not specified in the publication, temperature not specified in the publication
0.00564
benzoyl-Arg-7-amido-4-methylcoumarin
-
mutant E524Q, pH not specified in the publication, temperature not specified in the publication
0.00846
benzoyl-Arg-7-amido-4-methylcoumarin
-
mutant E490Q, pH not specified in the publication, temperature not specified in the publication
0.0212
benzoyl-Arg-7-amido-4-methylcoumarin
-
mutant E172Q, pH not specified in the publication, temperature not specified in the publication
0.0411
benzoyl-Arg-7-amido-4-methylcoumarin
-
mutant R689A, pH not specified in the publication, temperature not specified in the publication
0.00334
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
wild type enzyme, at 37°C
0.0044
benzoyl-L-Arg-7-amido-4-methylcoumarin
21°C, pH not specified in the publication
0.00528
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609Q, at 37°C
0.00568
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E610Q, at 37°C
0.00904
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609L, at 37°C
0.00913
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609F, at 37°C
0.0101
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609A, at 37°C
0.0113
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E607Q, at 37°C
0.0127
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E607Q/E609Q, at 37°C
0.0173
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609Q/E610Q, at 37°C
0.0184
benzoyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609R, at 37°C
0.084
benzoyl-L-Pro-L-Phe-L-Arg-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.00334
benzoyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
wild-type, pH not specified in the publication, temperature not specified in the publication
0.00421
benzoyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
mutant E524Q, pH not specified in the publication, temperature not specified in the publication
0.0108
benzoyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
mutant E490Q, pH not specified in the publication, temperature not specified in the publication
0.0185
benzoyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
mutant R689A, pH not specified in the publication, temperature not specified in the publication
0.034
benzoyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
-
mutant E172Q, pH not specified in the publication, temperature not specified in the publication
0.004
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D638Q
0.0044
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C
0.0045
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D599H
0.0046
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D460T and E494H
0.0047
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D462N
0.005
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D567H
0.0051
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, opdB with polyhistidine affinty tag removed
0.0052
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D460T/D462N
0.0054
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E624H
0.0164
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E578A
0.0334
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E576A
0.003
benzyloxycarbonyl-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.004
benzyloxycarbonyl-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.0008
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, wild-type and mutant D567H
0.00088
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, opdB with polyhistidine affinty tag removed
0.001
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E494H, E624H, and D599H
0.0011
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D638Q
0.0021
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D460T
0.0023
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D462N
0.0029
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D460T/D462N
0.0045
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E576A
0.00029
benzyloxycarbonyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin
-
mutant E524Q, pH not specified in the publication, temperature not specified in the publication
0.00063
benzyloxycarbonyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin
-
wild-type, pH not specified in the publication, temperature not specified in the publication
0.00078
benzyloxycarbonyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin
-
mutant R689A, pH not specified in the publication, temperature not specified in the publication
0.0011
benzyloxycarbonyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin
-
mutant E490Q, pH not specified in the publication, temperature not specified in the publication
0.0106
benzyloxycarbonyl-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin
-
mutant E172Q, pH not specified in the publication, temperature not specified in the publication
0.0029
benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.0033
benzyloxycarbonyl-Gly-Gly-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.00268
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
wild type enzyme, at 37°C
0.00525
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609A, at 37°C
0.00586
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E610Q, at 37°C
0.00637
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609L, at 37°C
0.0069
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609F, at 37°C
0.00728
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E607Q/E609Q, at 37°C
0.00807
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609Q, at 37°C
0.0127
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609Q/E610Q, at 37°C
0.015
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E607Q, at 37°C
0.0215
benzyloxycarbonyl-L-Arg-7-amido-4-methylcoumarin
-
mutant enzyme E609R, at 37°C
0.00036
benzyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin
-
mutant E524Q, pH not specified in the publication, temperature not specified in the publication
0.00117
benzyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin
-
wild-type, pH not specified in the publication, temperature not specified in the publication
0.00365
benzyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin
-
mutant E490Q, pH not specified in the publication, temperature not specified in the publication
0.00856
benzyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin
-
mutant R689A, pH not specified in the publication, temperature not specified in the publication
0.0177
benzyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin
-
mutant E172Q, pH not specified in the publication, temperature not specified in the publication
0.002
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D567H
0.0021
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, wild-type and mutant D599A; pH 8.0, 37°C, wild-type and mutant D599H
0.0025
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E494H
0.0026
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E624H
0.0028
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D638Q
0.0029
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D460T and D460T/D462N
0.003
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant D462N
0.0059
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E578A
0.012
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
pH 8.0, 37°C, mutant E576A
0.0023
benzyloxycarbonyl-Phe-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.003
benzyloxycarbonyl-Phe-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.00017
N2-benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin
-
mutant E524Q, pH not specified in the publication, temperature not specified in the publication
0.00027
N2-benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin
-
wild-type, pH not specified in the publication, temperature not specified in the publication
0.00043
N2-benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin
-
mutant E490Q, pH not specified in the publication, temperature not specified in the publication
0.00493
N2-benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin
-
mutant R689A, pH not specified in the publication, temperature not specified in the publication
0.00596
N2-benzyloxycarbonyl-Arg-Arg-7-amido-4-methylcoumarin
-
mutant E172Q, pH not specified in the publication, temperature not specified in the publication
0.302
Nalpha-benzoyl-DL-arginine-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.096
Nalpha-benzyloxycarbonyl-L-lysine thiobenzyl ester
-
pH 8.0, 25°C
0.322
Nalpha-benzyloxycarbonyl-L-lysine thiobenzyl ester
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.0513
Nalpha-benzyloxycarbonyl-L-Phe-L-Arg-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.058
Nalpha-benzyloxycarbonyl-L-Phe-L-Arg-4-nitroanilide
-
pH 8.0, 25°C
0.306
succinyl-L-AlaL-Ala-L-Pro-L-Arg-4-nitroanilide
-
presence of 50 mM Ca2+, pH 8.0, 25°C
0.0017
tert-butyloxycarbonyl-Ala-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.0021
tert-butyloxycarbonyl-Ala-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.0102
tert-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.0135
tert-butyloxycarbonyl-Ala-Gly-Pro-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.0013
tert-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.0021
tert-butyloxycarbonyl-Gly-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.0012
tert-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.0019
tert-butyloxycarbonyl-Gly-Lys-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.0008
tert-butyloxycarbonyl-Leu-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.001
tert-butyloxycarbonyl-Leu-Arg-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.0012
tert-butyloxycarbonyl-Leu-Gly-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, recombinant enzyme
0.0013
tert-butyloxycarbonyl-Leu-Gly-Arg-7-amido-4-methylcoumarin
pH 8.0, 37°C, native enzyme
0.001
tert-butyloxycarbonyl-Leu-Lys-Arg-7-amido-4-methylcoumarin