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Information on EC 3.4.21.47 - alternative-complement-pathway C3/C5 convertase

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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Cleavage of Arg-/-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-/- bond in complement component C5 alpha-chain to yield C5a and C5b
Synonyms
c3bbb, c5 convertase, properdin factor b, alternative pathway c3 convertase, c3b,bb, heat-labile factor, c3/c5 convertase, c3 proactivator, alternative c3 convertase, cvf,bb, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
Cleavage of Arg-/-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-/- bond in complement component C5 alpha-chain to yield C5a and C5b
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