Reference on EC 3.4.21.45 - complement factor I and Organism(s) Homo sapiens
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
topREF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ekdahl, K.N.; Nilsson, U.R.; Nilsson, B.
Inhibition of factor I by diisopropylfluorophosphate. Evidence of conformational changes in factor I induced by C3b and additional studies on the specificity of factor I
J. Immunol.
144
4269-4274
1990
Homo sapiens
Medicus, R.G.; Melamed, J.; Arnaout, M.A.
Role of human factor I and C3b receptor in the cleavage of surface-bound C3bi molecules
Eur. J. Immunol.
13
465-470
1983
Homo sapiens
Hsiung, L.; Barclay, A.N.; Brandon, M.R.; Sim, E.; Porter, R.R.
Purification of human C3b inactivator by monoclonal-antibody affinity chromatography
Biochem. J.
203
293-298
1982
Homo sapiens
Crossley, L.G.
C3b inactivator and beta1H
Methods Enzymol.
80
112-124
1981
Homo sapiens
Nagasawa, S.; Ichihara, C.; Stroud, R.M.
Cleavage of C4b by C3b inactivator: production of a nicked form of C4b, C4b', as an intermediate cleavage product of C4b by C3b inactivator
J. Immunol.
125
578-582
1980
Homo sapiens
Fujita, T.; Nussenzweig, V.
The role of C4-binding protein and beta1H in proteolysis of C4b and C3b
J. Exp. Med.
150
267-276
1979
Homo sapiens
Gaither, T.A.; Hammer, C.H.; Frank, M.M.
Studies of the molecular mechanisms of C3b inactivation and a simplified assay of beta1H and the C3b inactivator (C3bINA)
J. Immunol.
123
1195-1204
1979
Homo sapiens
DiScipio, R.G.
The fractionation of human plasma proteins
Protein Expr. Purif.
5
178-186
1994
Homo sapiens
Van den Berg, C.W.; Perez de la Lastra, J.M.; Llanes, D.; Morgan, B.P.
Purification and characterization of the pig analogue of human membrane cofactor protein (CD46/MCP)
J. Immunol.
158
1703-1709
1997
Homo sapiens, Sus scrofa
Ekdahl, K.N.; Nilsson, B.
Phosphorylation of complement component C3 and C3 fragments by a human platelet protein kinase
J. Immunol.
154
6402-6510
1995
Homo sapiens
-
Cunnion, K.M.; Hair, P.S.; Buescher, E.S.
Cleavage of complement C3b to iC3b on the surface of Staphylococcus aureus is mediated by serum complement factor I
Infect. Immun.
72
2858-2863
2004
Homo sapiens
Tsiftsoglou, S.A.; Sim, R.B.
Human complement factor I does not require cofactors for cleavage of synthetic substrates
J. Immunol.
173
367-375
2004
Homo sapiens
Tsiftsoglou, S.A.; Willis, A.C.; Li, P.; Chen, X.; Mitchell, D.A.; Rao, Z.; Sim, R.B.
The catalytically active serine protease domain of human complement factor I
Biochemistry
44
6239-6249
2005
Homo sapiens
Kavanagh, D.; Kemp, E.J.; Mayland, E.; Winney, R.J.; Duffield, J.S.; Warwick, G.; Richards, A.; Ward, R.; Goodship, J.A.; Goodship, T.H.
Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome
J. Am. Soc. Nephrol.
16
2150-2155
2005
Homo sapiens
Cunnion, K.M.; Buescher, E.S.; Hair, P.S.
Serum complement factor I decreases Staphylococcus aureus phagocytosis
J. Lab. Clin. Med.
146
279-286
2005
Homo sapiens
Tsiftsoglou, S.A.; Arnold, J.N.; Roversi, P.; Crispin, M.D.; Radcliffe, C.; Lea, S.M.; Dwek, R.A.; Rudd, P.M.; Sim, R.B.
Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides
Biochim. Biophys. Acta
1764
1757-1766
2006
Homo sapiens (P05156), Homo sapiens
Nilsson, S.C.; Karpman, D.; Vaziri-Sani, F.; Kristoffersson, A.C.; Salomon, R.; Provot, F.; Fremeaux-Bacchi, V.; Trouw, L.A.; Blom, A.M.
A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation
Mol. Immunol.
44
1835-1844
2007
Homo sapiens (P05156)
Timar, K.K.; Junnikkala, S.; Dallos, A.; Jarva, H.; Bhuiyan, Z.A.; Meri, S.; Bos, J.D.; Asghar, S.S.
Human keratinocytes produce the complement inhibitor factor I: Synthesis is regulated by interferon-gamma
Mol. Immunol.
44
2943-2949
2007
Homo sapiens (P05156), Homo sapiens
Okroj, M.; Hsu, Y.F.; Ajona, D.; Pio, R.; Blom, A.M.
Non-small cell lung cancer cells produce a functional set of complement factor I and its soluble cofactors
Mol. Immunol.
45
169-179
2008
Homo sapiens (P05156)
Kavanagh, D.; Richards, A.; Noris, M.; Hauhart, R.; Liszewski, M.K.; Karpman, D.; Goodship, J.A.; Fremeaux-Bacchi, V.; Remuzzi, G.; Goodship, T.H.; Atkinson, J.P.
Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome
Mol. Immunol.
45
95-105
2008
Homo sapiens (P05156)
Chan, M.R.; Thomas, C.P.; Torrealba, J.R.; Djamali, A.; Fernandez, L.A.; Nishimura, C.J.; Smith, R.J.; Samaniego, M.D.
Recurrent atypical hemolytic uremic syndrome associated with factor I mutation in a living related renal transplant recipient
Am. J. Kidney Dis.
53
321-326
2009
Homo sapiens
Fagerness, J.A.; Maller, J.B.; Neale, B.M.; Reynolds, R.C.; Daly, M.J.; Seddon, J.M.
Variation near complement factor I is associated with risk of advanced AMD
Eur. J. Hum. Genet.
17
100-104
2009
Homo sapiens
Nilsson, S.C.; Trouw, L.A.; Renault, N.; Miteva, M.A.; Genel, F.; Zelazko, M.; Marquart, H.; Muller, K.; Sjoeholm, A.G.; Truedsson, L.; Villoutreix, B.O.; Blom, A.M.
Genetic, molecular and functional analyses of complement factor I deficiency
Eur. J. Immunol.
39
310-323
2009
Homo sapiens
Yuasa, I.; Nakagawa, M.; Umetsu, K.; Harihara, S.; Matsusue, A.; Nishimukai, H.; Fukumori, Y.; Saitou, N.; Park, K.S.; Jin, F.; Lucotte, G.; Chattopadhyay, P.K.; Henke, L.; Henke, J.
Molecular basis of complement factor I (CFI) polymorphism: one of two polymorphic suballeles responsible for CFI A is Japanese-specific
J. Hum. Genet.
53
1016-1021
2008
Homo sapiens
Wang, J.; Ohno-Matsui, K.; Yoshida, T.; Kojima, A.; Shimada, N.; Nakahama, K.; Safranova, O.; Iwata, N.; Saido, T.C.; Mochizuki, M.; Morita, I.
Altered function of factor I caused by amyloid beta: implication for pathogenesis of age-related macular degeneration from Drusen
J. Immunol.
181
712-720
2008
Homo sapiens, Mus musculus
Hair, P.S.; Ward, M.D.; Semmes, O.J.; Foster, T.J.; Cunnion, K.M.
Staphylococcus aureus clumping factor A binds to complement regulator factor I and increases factor I cleavage of C3b
J. Infect. Dis.
198
125-133
2008
Homo sapiens
Ponce-Castro, I.M.; Gonzalez-Rubio, C.; Delgado-Cervino, E.M.; Abarrategui-Garrido, C.; Fontan, G.; Sanchez-Corral, P.; Lopez-Trascasa, M.
Molecular characterization of Complement Factor I deficiency in two Spanish families
Mol. Immunol.
45
2764-2771
2008
Homo sapiens
Nakahata, K.; Matsunami, K.; Kobayashi, C.; Omori, T.; Xu, H.; Firdawes, S.; Fukuzawa, M.; Miyagawa, S.
Analysis of the serine protease function of porcine factor I produced by liver cells for xenotransplantation
Transpl. Immunol.
19
30-36
2008
Homo sapiens (P05156), Homo sapiens, Sus scrofa
Nilsson, S.C.; Kalchishkova, N.; Trouw, L.A.; Fremeaux-Bacchi, V.; Villoutreix, B.O.; Blom, A.M.
Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I
Eur. J. Immunol.
40
172-185
2010
Homo sapiens
Hair, P.S.; Echague, C.G.; Sholl, A.M.; Watkins, J.A.; Geoghegan, J.A.; Foster, T.J.; Cunnion, K.M.
Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of Staphylococcus aureus and decreases complement-mediated phagocytosis
Infect. Immun.
78
1717-1727
2010
Homo sapiens
Ennis, S.; Gibson, J.; Cree, A.; Collins, A.; Lotery, A.
Support for the involvement of complement factor I in age-related macular degeneration
Eur. J. Hum. Genet.
18
15-16
2010
Homo sapiens
Roversi, P.; Johnson, S.; Caesar, J.J.; McLean, F.; Leath, K.J.; Tsiftsoglou, S.A.; Morgan, B.P.; Harris, C.L.; Sim, R.B.; Lea, S.M.
Structural basis for complement factor I control and its disease-associated sequence polymorphisms
Proc. Natl. Acad. Sci. USA
108
12839-12844
2011
Homo sapiens
Sanchez-Gallego, J.I.; Groeneveld, T.W.; Krentz, S.; Nilsson, S.C.; Villoutreix, B.O.; Blom, A.M.
Analysis of binding sites on complement factor I using artificial N-linked glycosylation
J. Biol. Chem.
287
13572-13583
2012
Homo sapiens
Broderick, L.; Gandhi, C.; Mueller, J.L.; Putnam, C.D.; Shayan, K.; Giclas, P.C.; Peterson, K.S.; Aceves, S.S.; Sheets, R.M.; Peterson, B.M.; Newbury, R.O.; Hoffman, H.M.; Bastian, J.F.
Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis
J. Clin. Immunol.
33
162-171
2013
Homo sapiens
Malm, S.; Jusko, M.; Eick, S.; Potempa, J.; Riesbeck, K.; Blom, A.M.
Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia
PLoS ONE
7
e34852
2012
Homo sapiens
Okroj, M.; Holmquist, E.; Nilsson, E.; Anagnostaki, L.; Jirstroem, K.; Blom, A.M.
Local expression of complement factor I in breast cancer cells correlates with poor survival and recurrence
Cancer Immunol. Immunother.
64
467-478
2015
Homo sapiens
Kumar, J.; Yadav, V.; Phulera, S.; Kamble, A.; Gautam, A.; Panwar, H.; Sahu, A.
Species specificity of vaccinia virus complement control protein for the bovine classical pathway is governed primarily by direct interaction of its acidic residues with factor I
J. Virol.
91
e00668-17
2017
Bos taurus, Homo sapiens
