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Reference on EC 3.4.21.113 - pestivirus NS3 polyprotein peptidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Xu, J.; Mendez, E.; Caron, P.R.; Lin, C.; Murcko, M.A.; Collett, M.S.; Rice, C.M.
Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication
J. Virol.
71
5312-5322
1997
Bovine viral diarrhea virus 1, Bovine viral diarrhea virus 1 NADL
Manually annotated by BRENDA team
Tautz, N.; Elbers, K.; Stoll, D.; Meyers, G.; Thiel, H.J.
Serine protease of pestiviruses: determination of cleavage sites
J. Virol.
71
5415-5422
1997
Bovine viral diarrhea virus 1, Bovine viral diarrhea virus 1 CP7
Manually annotated by BRENDA team
Deng, R.; Brock, K.V.
Molecular cloning and nucleotide sequence of a pestivirus genome, noncytopathic bovine viral diarrhea virus strain SD-1
Virology
191
867-869
1992
Bovine viral diarrhea virus 1 (Q01499), Bovine viral diarrhea virus 1 SD-1 (Q01499)
Manually annotated by BRENDA team
Tautz, N.; Kaiser, A.; Thiel, H.J.
NS3 serine protease of bovine viral diarrhea virus: characterization of active site residues, NS4A cofactor domain, and protease-cofactor interactions
Virology
273
351-363
2000
Bovine viral diarrhea virus 1
Manually annotated by BRENDA team
Chen, K.X.; Njoroge, F.G.; Arasappan, A.; Venkatraman, S.; Vibulbhan, B.; Yang, W.; Parekh, T.N.; Pichardo, J.; Prongay, A.; Cheng, K.C.; Butkiewicz, N.; Yao, N.; Madison, V.; Girijavallabhan, V.
Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles
J. Med. Chem.
49
995-1005
2006
Hepacivirus C
Manually annotated by BRENDA team
Wiskerchen, M.; Collett, M.S.
Pestvirus gene expression: protein p80 of bovine viral diarrhea virus is a proteinase involved in polyprotein processing
Virology
184
341-350
1991
Bovine viral diarrhea virus 1
Manually annotated by BRENDA team
Zuo, G.; Li, Z.; Chen, L.; Xu, X.
Activity of compounds from Chinese herbal medicine Rhodiola kirilowii (Regel) Maxim against HCV NS3 serine protease
Antiviral Res.
76
86-92
2007
Hepacivirus C
Manually annotated by BRENDA team
Li, X.; Zhang, W.; Qiao, X.; Xu, X.
Prediction of binding for a kind of non-peptic HCV NS3 serine protease inhibitors from plants by molecular docking and MM-PBSA method
Bioorg. Med. Chem.
15
220-226
2007
Hepacivirus C
Manually annotated by BRENDA team
Chen, K.X.; Vibulbhan, B.; Yang, W.; Cheng, K.C.; Liu, R.; Pichardo, J.; Butkiewicz, N.; Njoroge, F.G.
Potent and selective small molecule NS3 serine protease inhibitors of Hepatitis C virus with dichlorocyclopropylproline as P2 residue
Bioorg. Med. Chem.
16
1874-1883
2008
Hepacivirus C
Manually annotated by BRENDA team
Beran, R.K.; Serebrov, V.; Pyle, A.M.
The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate
J. Biol. Chem.
282
34913-34920
2007
Hepacivirus C
Manually annotated by BRENDA team
Bogen, S.L.; Arasappan, A.; Bennett, F.; Chen, K.; Jao, E.; Liu, Y.T.; Lovey, R.G.; Venkatraman, S.; Pan, W.; Parekh, T.; Pike, R.E.; Ruan, S.; Liu, R.; Baroudy, B.; Agrawal, S.; Chase, R.; Ingravallo, P.; Pichardo, J.; Prongay, A.; Brisson, J.M.; Hsieh, T.Y.; Cheng, K.C.; Kemp, S.J.; Levy, O.E.; Lim-Wilby, M.; Tamura, S.Y.; Saksena, A.K.; Girijavallabhan, V.; Njoroge, F.G.
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication
J. Med. Chem.
49
2750-2757
2006
Hepacivirus C
Manually annotated by BRENDA team
Chernov, A.V.; Shiryaev, S.A.; Aleshin, A.E.; Ratnikov, B.I.; Smith, J.W.; Liddington, R.C.; Strongin, A.Y.
The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase
J. Biol. Chem.
283
17270-17278
2008
West Nile virus (Q3HM13)
Manually annotated by BRENDA team
Condotta, S.A.; Martin, M.M.; Boutin, M.; Jean, F.
Detection and in-cell selectivity profiling of the full-length West Nile virus NS2B/NS3 serine protease using membrane-anchored fluorescent substrates
Biol. Chem.
391
549-559
2010
West Nile virus
Manually annotated by BRENDA team
Lim, H.A.; Joy, J.; Hill, J.; San Brian Chia, C.
Novel agmatine and agmatine-like peptidomimetic inhibitors of the West Nile virus NS2B/NS3 serine protease
Eur. J. Med. Chem.
46
3130-3134
2011
West Nile virus
Manually annotated by BRENDA team
Lamp, B.; Riedel, C.; Wentz, E.; Tortorici, M.A.; Ruemenapf, T.
Autocatalytic cleavage within classical swine fever virus NS3 leads to a functional separation of protease and helicase
J. Virol.
87
11872-11883
2013
Classical swine fever virus (P19712)
Manually annotated by BRENDA team
Riedel, C.; Lamp, B.; Heimann, M.; Koenig, M.; Blome, S.; Moennig, V.; Schuettler, C.; Thiel, H.J.; Ruemenapf, T.
The core protein of classical Swine Fever virus is dispensable for virus propagation in vitro
PLoS Pathog.
8
e1002598
2012
Classical swine fever virus (P19712)
Manually annotated by BRENDA team
Zheng, F.; Lu, G.; Li, L.; Gong, P.; Pan, Z.
Uncoupling of protease trans-cleavage and helicase activities in pestivirus NS3
J. Virol.
91
e01094-17
2017
Classical swine fever virus (Q5U8X5), Classical swine fever virus
Manually annotated by BRENDA team
Dubrau, D.; Tortorici, M.A.; Rey, F.A.; Tautz, N.
A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis
PLoS Pathog.
13
e1006134
2017
Classical swine fever virus (Q5U8X5)
Manually annotated by BRENDA team