Disease on EC 3.4.21.113 - pestivirus NS3 polyprotein peptidase
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DISEASE 
TITLE OF PUBLICATION
LINK TO PUBMED
African Horse Sickness
Expression of nonstructural protein NS3 of African horsesickness virus (AHSV): evidence for a cytotoxic effect of NS3 in insect cells, and characterization of the gene products in AHSV infected Vero cells.
African Horse Sickness
Membrane association of African horsesickness virus nonstructural protein NS3 determines its cytotoxicity.
African Horse Sickness
Subcellular localization of the nonstructural protein NS3 of African horsesickness virus.
African Horse Sickness
Variation of African horsesickness virus nonstructural protein NS3 in southern Africa.
Autoimmune Diseases
Hepatitis C virus nonstructural protein NS3 binds to Sm-D1, a small nuclear ribonucleoprotein associated with autoimmune disease.
Carcinogenesis
[Effect of hepatitis C virus nonstructural protein NS3 on telomerase activity]
Dengue
A single nine-amino acid peptide induces virus-specific, CD8+ human cytotoxic T lymphocyte clones of heterogeneous serotype specificities.
Dengue
Dengue virus-specific, human CD4+ CD8- cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones.
Dengue
Modulation of enzymatic activity of dengue virus nonstructural protein NS3 nucleoside triphosphatase/helicase by poly(U).
Encephalitis, Japanese
Japanese encephalitis virus nonstructural protein NS3 has RNA binding and ATPase activities.
Hepatitis C
Effect of hepatitis C virus nonstructural protein NS3 on proliferation and MAPK phosphorylation of normal hepatocyte line.
Hepatitis C
Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3.
Hepatitis C
Hepatitis C virus nonstructural protein NS3 binds to Sm-D1, a small nuclear ribonucleoprotein associated with autoimmune disease.
Hepatitis C
IgE antibodies to hepatitis C virus core and nonstructural antigens in chronic hepatitis C patients before and after antiviral treatment.
Hepatitis C
Inhibition of sphingosine kinase by bovine viral diarrhea virus NS3 is crucial for efficient viral replication and cytopathogenesis.
Hepatitis C
Internal cleavage of hepatitis C virus NS3 protein is dependent on the activity of NS34A protease.
Hepatitis C
Screening factors effecting a response in soluble protein expression: formalized approach using design of experiments.
Hepatitis C
Significance of the immune response to a major, conformational B-cell epitope on the hepatitis C virus NS3 region defined by a human monoclonal antibody.
Hepatitis C
The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication.
Hepatitis C
[The combined application of nucleotide and amino acid sequences of NS3 hepatitis C virus protein, DNA encoding granulocyte macrophage colony-stimulating factor and inhibitor of regulatory T cells induces effective immune response against hepatitis C virus].
Hepatitis C, Chronic
IgE antibodies to hepatitis C virus core and nonstructural antigens in chronic hepatitis C patients before and after antiviral treatment.
Infections
Cytopathogenicity of border disease virus is correlated with integration of cellular sequences into the viral genome.
Infections
Dengue virus-specific, human CD4+ CD8- cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones.
Infections
Development of an immunochromatographic test kit for rapid detection of bovine viral diarrhea virus antigen.
Infections
Rescue of the highly virulent classical swine fever virus strain "Koslov" from cloned cDNA and first insights into genome variations relevant for virulence.
Infections
The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication.
Infections
[Replication complex of tick-borne encephalitis complex. I. Identification of a nuclear fraction protein responsible for the initiation of RNA synthesis using affinity labeling]
Virus Diseases
An insect cell line derived from the small brown planthopper supports replication of Rice stripe virus, a tenuivirus.
Yellow Fever
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.
Yellow Fever
Interaction between the yellow fever virus nonstructural protein NS3 and the host protein Alix contributes to the release of infectious particles.
Yellow Fever
RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria.
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