Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 3.4.21.104 - mannan-binding lectin-associated serine protease-2 and Organism(s) Homo sapiens

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma of Lung
Analysis of genomic and transcriptomic variations as prognostic signature for lung adenocarcinoma.
Arthritis, Rheumatoid
Association of MASP-2 Levels and MASP2 Gene Polymorphisms with Rheumatoid Arthritis in Patients and Their Relatives.
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
Autoimmune Diseases
Bipolar and panic disorders may be associated with hereditary defects in the innate immune system.
Bacteremia
Polymorphic receptors of the innate immune system (MBL/MASP-2 and TLR2/4) and susceptibility to pneumococcal bacteremia in HIV-infected patients: a case-control study.
The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT).
Carcinoma
Clinical significance of mannose-binding lectin-associated serine protease-2 expression in esophageal squamous cell carcinoma.
Mannan-binding lectin (MBL)-associated plasma protein present in human urine inhibits calcium oxalate crystal growth.
Carcinoma, Hepatocellular
MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma.
Carcinoma, Renal Cell
Mannan-binding lectin (MBL)-associated plasma protein present in human urine inhibits calcium oxalate crystal growth.
Cardiomyopathies
Identification of critical regions and candidate genes for cardiovascular malformations and cardiomyopathy associated with deletions of chromosome 1p36.
MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease.
Cardiovascular Diseases
Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?
Chagas Disease
Deficiency in Mannose-Binding Lectin-Associated Serine Protease-2 Does Not Increase Susceptibility to Trypanosoma cruzi Infection.
Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.
MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease.
Coinfection
A dual role for Mannan-binding lectin-associated serine protease 2 (MASP-2) in HIV infection.
Colorectal Neoplasms
Biological variation in circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the influence of age, gender and physical exercise.
Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) genotypes in colorectal cancer.
Pre- and postoperative levels in serum of mannan-binding lectin associated serine protease-2 -a prognostic marker in colorectal cancer.
Serum mannan-binding lectin-associated serine protease 2 levels in colorectal cancer: relation to recurrence and mortality.
Coma
The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials.
Communicable Diseases
Multiple Infectious Complications in a Severely Injured Patient with Single Nucleotide Polymorphisms in Important Innate Immune Response Genes.
Coronavirus Infections
Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.
COVID-19
Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19.
Dental Caries
MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children.
Diabetes Mellitus, Type 1
Incident microalbuminuria and complement factor mannan-binding lectin-associated protein 19 in people with newly diagnosed type 1 diabetes.
Diabetic Nephropathies
[Triperygium wilfordii multiglucoside ameliorates kidney damage in diabetic rats by inhibiting the expressions of MBL and MASP2].
Endometrial Neoplasms
Distinct clinical and genetic mutation characteristics in sporadic and Lynch syndrome-associated endometrial cancer in a Chinese population.
Enterocolitis
Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis.
Esophageal Squamous Cell Carcinoma
Clinical significance of mannose-binding lectin-associated serine protease-2 expression in esophageal squamous cell carcinoma.
Frontotemporal Dementia
No association of TDP-43 with sporadic frontotemporal dementia.
Gout
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Graft vs Host Disease
Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation.
Hematologic Neoplasms
Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2).
Hepatitis
Effects of MASP2 haplotypes and MASP-2 levels in hepatitis C-infected patients.
Hepatitis C
Effects of MASP2 haplotypes and MASP-2 levels in hepatitis C-infected patients.
MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection.
Hepatitis C, Chronic
MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection.
HIV Infections
A dual role for Mannan-binding lectin-associated serine protease 2 (MASP-2) in HIV infection.
Polymorphic receptors of the innate immune system (MBL/MASP-2 and TLR2/4) and susceptibility to pneumococcal bacteremia in HIV-infected patients: a case-control study.
Infections
Association of MASP-2 Levels and MASP2 Gene Polymorphisms with Rheumatoid Arthritis in Patients and Their Relatives.
Bipolar and panic disorders may be associated with hereditary defects in the innate immune system.
Deficiency in Mannose-Binding Lectin-Associated Serine Protease-2 Does Not Increase Susceptibility to Trypanosoma cruzi Infection.
Mannose binding lectin and mannose binding lectin-associated serine protease-2 genes polymorphisms in human T-lymphotropic virus infection.
Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants.
Multiplex sequence-specific polymerase chain reaction reveals new MASP2 haplotypes associated with MASP-2 and MAp19 serum levels.
[Plasma levels of mannan-binding lectin-associated serine protease 2 in children with upper respiratory tract infection].
Ischemic Stroke
Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.
Leprosy
Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5.
Liver Neoplasms
Metadata checklist: identification of CHI3L1 and MASP2 as a biomarker pair for liver cancer through integrative secretome and transcriptome analysis.
Lung Diseases
Association analysis reveals genetic variation altering bleomycin-induced pulmonary fibrosis in mice.
The mannan-binding lectin pathway and lung disease in cystic fibrosis--disfunction of mannan-binding lectin-associated serine protease 2 (MASP-2) may be a major modifier.
Lung Injury
Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab.
Lupus Erythematosus, Systemic
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Lymphoma
The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT).
Lymphoma, B-Cell
Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma.
Lymphoma, Follicular
Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma.
Lymphoma, Large B-Cell, Diffuse
Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma.
Malaria
Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria.
mannan-binding lectin-associated serine protease-2 deficiency
Low clinical penetrance of mannose-binding lectin-associated serine protease 2 deficiency.
Meningitis, Bacterial
Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
Meningitis, Pneumococcal
Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
Neonatal Sepsis
Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants.
Neoplasms
Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients.
Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours.
Neutropenia
Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients.
Osteoarthritis
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Out-of-Hospital Cardiac Arrest
The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials.
Ovarian Neoplasms
Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours.
Pancreatitis
Mannan-binding lectin and mannan-binding lectin-associated serine protease 2 in acute pancreatitis.
Pemphigus
Circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease 2 in endemic pemphigus foliaceus.
Persistent Infection
Construction of human MASP-2-CCP1/2SP, CCP2SP, SP plasmid DNA nanolipoplexes and the effects on tuberculosis in BCG-infected mice.
Pneumococcal Infections
Polymorphic receptors of the innate immune system (MBL/MASP-2 and TLR2/4) and susceptibility to pneumococcal bacteremia in HIV-infected patients: a case-control study.
Serotype-specific pneumococcal disease may be influenced by MBL-deficiency.
Pneumonia
Clinical and immunogenetic factors associated with pneumonia in patients with systemic lupus erythematosus: a case-control study.
Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults.
Proteinuria
The Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus.
Psoriasis
Functional MASP2 single nucleotide polymorphism plays no role in psoriasis.
Reperfusion Injury
Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.
Rheumatic Diseases
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Rheumatic Fever
Association of MASP2 polymorphisms and protein levels with rheumatic fever and rheumatic heart disease.
Functional MASP2 gene polymorphism in patients with history of rheumatic fever.
Rheumatic Heart Disease
Association of MASP2 polymorphisms and protein levels with rheumatic fever and rheumatic heart disease.
Schistosomiasis haematobia
Low MBL-associated serine protease 2 (MASP-2) levels correlate with urogenital schistosomiasis in Nigerian children.
Sepsis
Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?
Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants.
Sjogren's Syndrome
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Spondylitis, Ankylosing
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Starvation
Environmental conditions impinge on dragline silk protein composition.
Stroke
Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke.
Thrombotic Microangiopathies
MASP2 levels are elevated in thrombotic microangiopathies: association with microvascular endothelial cell injury and suppression by anti-MASP2 antibody narsoplimab.
Tuberculosis
Construction of human MASP-2-CCP1/2SP, CCP2SP, SP plasmid DNA nanolipoplexes and the effects on tuberculosis in BCG-infected mice.
Impact of MASP2 gene polymorphism and gene-tea drinking interaction on susceptibility to tuberculosis.
Tuberculosis, Pulmonary
Mannan-binding lectin-associated serine protease-2 (MASP-2) deficiency in two patients with pulmonary tuberculosis and one healthy control.
Virus Diseases
MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection.
MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma.
West Nile Fever
The lectin pathway of complement activation contributes to protection from West Nile virus infection.