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(Gly-Pro-Ala)n + H2O
Gly-Pro + Ala
-
-
-
?
Ala-Ala-2-naphthylamide + H2O
Ala-Ala + 2-naphthylamine
Ala-Ala-2-nitroanilide + H2O
Ala-Ala + 2-nitroaniline
-
low activity
-
?
Ala-Ala-4-nitroanilide + H2O
Ala-Ala + 4-nitroaniline
Ala-Ala-Ala + H2O
Ala-Ala + Ala
-
54% activity compared to Met-Ala-Ser
-
-
?
Ala-Ala-Ala-Ala + H2O
Ala-Ala + Ala-Ala
-
39% activity compared to Met-Ala-Ser
-
-
?
Ala-Ala-p-nitroanilide + H2O
Ala-Ala + p-nitroaniline
-
481% activity compared to Gly-Pro-7-amido-4-methylcoumarin
-
-
?
Ala-Ala-Phe-OH + H2O
Ala-Ala + Phe-OH
Ala-Phe-4-nitroanailide + H2O
Ala-Phe + 4-nitroaniline
Ala-Pro-2-(4-methoxy)-naphthylamine + H2O
?
Ala-Pro-4-nitroanilide + H2O
Ala-Pro + 4-nitroaniline
-
-
-
-
?
Ala-Pro-amino-4-trifluoromethylcoumarin + H2O
Ala-Pro + amino-4-trifluoromethylcoumarin
Ala-Pro-p-nitroanilide + H2O
Ala-Pro + p-nitroaniline
Arg-Ala-2-naphthylamide + H2O
Arg-Ala + 2-naphthylamine
Arg-Pro-2-naphthylamide + H2O
Arg-Pro + 2-naphthylamine
-
27% of the activity with Phe-Pro-2-naphthylamide
-
-
?
Arg-Pro-4-nitroanilide + H2O
Arg-Pro + 4-nitroaniline
Arg-Pro-Lys-Pro + H2O
Arg-Pro + Lys-Pro
Arg-Pro-p-nitroanilide + H2O
Arg-Pro + p-nitroaniline
Asn-Pro-p-nitroanilide + H2O
Asn-Pro + p-nitroaniline
-
-
-
?
Asp-Pro-4-nitroanilide + H2O
Asp-Pro + 4-nitroaniline
-
-
-
-
?
azocasein + H2O
?
-
-
-
-
?
bradykinin fragment 1-3 + H2O
?
-
-
-
-
?
bradykinin fragment 1-5 + H2O
?
-
-
-
-
?
Glu-Pro-4-nitroanilide + H2O
Glu-Pro + 4-nitroaniline
Gly-Ala-7-amido-4-methylcoumarin + H2O
Gly-Ala + 7-amino-4-methylcoumarin
-
-
?
Gly-Ala-Ala + H2O
Gly-Ala + Ala
-
-
-
-
?
Gly-L-Pro-4-nitroanilide + H2O
Gly-L-Pro + 4-nitroaniline
-
-
-
-
?
Gly-Pro-2-(4-methoxy)-naphthylamide + H2O
?
-
-
-
-
?
Gly-Pro-2-naphthylamide + H2O
Gly-Pro + 2-naphthylamine
-
-
-
-
?
Gly-Pro-4-methylcoumarin 7-amide + H2O
Gly-Pro + 7-amino-4-methylcoumarin
-
-
-
-
?
Gly-Pro-4-nitroanilide + H2O
Gly-Pro + 4-nitroaniline
Gly-Pro-7-amido-4-methylcoumarin + H2O
Gly-Pro + 7-amino-4-methylcoumarin
Gly-Pro-Ala + H2O
Gly-Pro + Ala
Gly-Pro-Gly-Gly + H2O
Gly-Pro + Gly-Gly
-
16% activity compared to Met-Ala-Ser
-
-
?
Gly-Pro-Leu-Gly + H2O
?
-
-
-
-
?
Gly-Pro-p-nitroanilide + H2O
Gly-Pro + p-nitroaniline
His-Ala-p-nitroanilide + H2O
His-Ala + p-nitroaniline
-
-
-
?
His-Pro-p-nitroanilide + H2O
His-Pro + p-nitroaniline
-
-
-
?
His-Pro-Val + H2O
His-Pro + Val
-
-
-
-
?
L-Lys-L-Ala-5-chloro-1-anthraquinonylhydrazide-2HBr + H2O
L-Lys-L-Ala + 5-Cl-1-anthraquinonylhydrazine + HBr
-
i.e. Lys-Ala-CAH, synthetic substrate for colorimetric assay
i.e. CAH, forms a highly insoluble, deeply colored hydrazone when coupled to an aromatic aldehyde, e.g. 4-nitrobenzaldehyde or piperonal, useful for histochemical detection of the enzyme
?
L-Lys-L-Ala-7-amido-4-methylcoumarin + H2O
L-Lys-L-Ala + 7-amino-4-methylcoumarin
Leu-Ala-2-naphthylamide + H2O
Leu-Ala + 2-naphthylamine
Lys-Ala-2-(4-methoxy)-naphthylamide Lys-Ala-4-methoxy-2-naphthylamide + H2O
?
Lys-Ala-2-naphthylamide + H2O
Lys-Ala + 2-naphthylamine
Lys-Ala-4-methylcoumaryl-7-amide + H2O
Lys-Ala + 7-amino-4-methylcoumarin
Lys-Ala-7-amido-4-methylcoumarin + H2O
Lys-Ala + 7-amino-4-methylcoumarin
Lys-Ala-Ala + H2O
Lys-Ala + Ala
Lys-Ala-OCH3 + H2O
?
-
-
-
-
?
Lys-Ala-p-nitroanilide + H2O
Lys-Ala + p-nitroaniline
-
-
-
?
Lys-Ala-Pro + H2O
Lys-Ala + Pro
-
-
-
-
?
Lys-Arg-2-naphthylamide + H2O
Lys-Arg + 2-naphthylamine
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamide + H2O
?
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamine + H2O
?
Lys-Pro-2-naphthylamide + H2O
Lys-Pro + 2-naphthylamine
Lys-Pro-4-nitroanilide + H2O
Lys-Pro + 4-nitroaniline
Lys-Pro-7-amido-4-methylcoumarin + H2O
Lys-Pro + 7-amino-4-methylcoumarin
-
-
?
Lys-Pro-p-nitroanilide + H2O
Lys-Pro + p-nitroaniline
Met-Ala-Ser + H2O
Met-Ala + Ser
-
100% activity
-
-
?
Met-Met-Ala + H2O
Met-Met + Ala
-
-
-
-
?
Met-Met-Met + H2O
Met-Met + Met
-
-
-
-
?
Nle-Nle-p-nitroanilide + H2O
Nle-Nle + p-nitroaniline
-
-
-
?
Nle-Nle-rhodamine + H2O
Nle-Nle + rhodamine
-
-
?
Nle-Pro-7-amido-4-methylcoumarin + H2O
Nle-Pro + 7-amino-4-methylcoumarin
-
-
?
Nle-Pro-rhodamine + H2O
Nle-Pro + rhodamine
-
-
?
Phe-Pro-2-naphthylamide + H2O
Phe-Pro + 2-naphthylamine
Phe-Pro-4-methylcoumarin 7-amide + H2O
Phe-Pro + 7-amino-4-methylcoumarin
-
-
-
-
?
Phe-Pro-Ala + H2O
Phe-Pro + Ala
-
-
-
-
?
Phe-Pro-p-nitroanilide + H2O
Phe-Pro + p-nitroaniline
-
-
-
?
Pro-Ala-p-nitroanilide + H2O
Pro-Ala + p-nitroaniline
-
-
-
?
Ser-Met-Gln + H2O
Ser-Met + Gln
-
-
-
-
?
Ser-Met-Glu + H2O
Ser-Met + Glu
-
-
-
-
?
Ser-Met-OCH3 + H2O
?
-
-
-
-
?
Ser-Pro-p-nitroanilide + H2O
Ser-Pro + p-nitroaniline
-
-
-
?
Tyr-Ala-p-nitroanilide + H2O
Tyr-Ala + p-nitroaniline
-
-
-
?
Val-Ala-4-nitroanilide + H2O
Val-Ala + 4-nitroaniline
-
-
-
-
?
Val-Ala-Phe-OH + H2O
Val-Ala + Phe-OH
additional information
?
-
(Ala)3 + H2O
?
-
L-Ala3
-
-
?
Ala-Ala-2-naphthylamide + H2O
Ala-Ala + 2-naphthylamine
-
-
-
-
?
Ala-Ala-2-naphthylamide + H2O
Ala-Ala + 2-naphthylamine
-
-
-
-
?
Ala-Ala-4-nitroanilide + H2O
Ala-Ala + 4-nitroaniline
-
-
-
-
?
Ala-Ala-4-nitroanilide + H2O
Ala-Ala + 4-nitroaniline
-
-
-
-
?
Ala-Ala-Phe-OH + H2O
Ala-Ala + Phe-OH
-
-
-
?
Ala-Ala-Phe-OH + H2O
Ala-Ala + Phe-OH
-
-
-
?
Ala-Phe-4-nitroanailide + H2O
Ala-Phe + 4-nitroaniline
-
-
-
?
Ala-Phe-4-nitroanailide + H2O
Ala-Phe + 4-nitroaniline
-
-
-
?
Ala-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Ala-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Ala-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Ala-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Ala-Pro-amino-4-trifluoromethylcoumarin + H2O
Ala-Pro + amino-4-trifluoromethylcoumarin
-
-
?
Ala-Pro-amino-4-trifluoromethylcoumarin + H2O
Ala-Pro + amino-4-trifluoromethylcoumarin
-
-
-
?
Ala-Pro-p-nitroanilide + H2O
Ala-Pro + p-nitroaniline
-
-
-
-
?
Ala-Pro-p-nitroanilide + H2O
Ala-Pro + p-nitroaniline
-
-
-
?
Arg-Ala-2-naphthylamide + H2O
Arg-Ala + 2-naphthylamine
-
-
-
-
?
Arg-Ala-2-naphthylamide + H2O
Arg-Ala + 2-naphthylamine
-
11% of the activity with Phe-Pro-2-naphthylamide
-
-
?
Arg-Pro-4-nitroanilide + H2O
Arg-Pro + 4-nitroaniline
-
-
-
-
?
Arg-Pro-4-nitroanilide + H2O
Arg-Pro + 4-nitroaniline
-
-
-
-
?
Arg-Pro-Lys-Pro + H2O
Arg-Pro + Lys-Pro
-
fragments of substance P
-
-
?
Arg-Pro-Lys-Pro + H2O
Arg-Pro + Lys-Pro
fragments of substance P
-
-
?
Arg-Pro-Lys-Pro + H2O
Arg-Pro + Lys-Pro
-
fragments of substance P
-
-
?
Arg-Pro-Lys-Pro + H2O
Arg-Pro + Lys-Pro
-
fragments of substance P
-
-
?
Arg-Pro-p-nitroanilide + H2O
Arg-Pro + p-nitroaniline
-
-
-
?
Arg-Pro-p-nitroanilide + H2O
Arg-Pro + p-nitroaniline
-
591% activity compared to Gly-Pro-7-amido-4-methylcoumarin
-
-
?
bradykinin + H2O
?
-
-
-
-
?
bradykinin + H2O
?
-
-
-
?
bradykinin + H2O
?
-
-
-
-
?
bradykinin + H2O
?
-
-
-
-
?
casomorphin + H2O
?
-
-
-
-
?
casomorphin + H2O
?
-
-
-
?
casomorphin + H2O
?
-
-
-
-
?
casomorphin + H2O
?
-
-
-
-
?
Glu-Pro-4-nitroanilide + H2O
Glu-Pro + 4-nitroaniline
-
-
-
-
?
Glu-Pro-4-nitroanilide + H2O
Glu-Pro + 4-nitroaniline
-
-
-
-
?
Gly-Pro-4-nitroanilide + H2O
Gly-Pro + 4-nitroaniline
-
-
-
-
?
Gly-Pro-4-nitroanilide + H2O
Gly-Pro + 4-nitroaniline
-
specific for proline
-
?
Gly-Pro-4-nitroanilide + H2O
Gly-Pro + 4-nitroaniline
-
-
-
-
?
Gly-Pro-4-nitroanilide + H2O
Gly-Pro + 4-nitroaniline
-
-
-
-
?
Gly-Pro-4-nitroanilide + H2O
Gly-Pro + 4-nitroaniline
-
specific for proline
-
?
Gly-Pro-7-amido-4-methylcoumarin + H2O
Gly-Pro + 7-amino-4-methylcoumarin
-
-
?
Gly-Pro-7-amido-4-methylcoumarin + H2O
Gly-Pro + 7-amino-4-methylcoumarin
-
-
-
?
Gly-Pro-7-amido-4-methylcoumarin + H2O
Gly-Pro + 7-amino-4-methylcoumarin
-
100% activity
-
-
?
Gly-Pro-Ala + H2O
Gly-Pro + Ala
-
96% activity compared to Met-Ala-Ser
-
-
?
Gly-Pro-Ala + H2O
Gly-Pro + Ala
-
-
-
-
?
Gly-Pro-Ala + H2O
Gly-Pro + Ala
-
-
-
-
?
Gly-Pro-p-nitroanilide + H2O
Gly-Pro + p-nitroaniline
-
-
-
-
?
Gly-Pro-p-nitroanilide + H2O
Gly-Pro + p-nitroaniline
-
-
-
?
Gly-Pro-p-nitroanilide + H2O
Gly-Pro + p-nitroaniline
-
562% activity compared to Gly-Pro-7-amido-4-methylcoumarin
-
-
?
L-Lys-L-Ala-7-amido-4-methylcoumarin + H2O
L-Lys-L-Ala + 7-amino-4-methylcoumarin
-
-
-
-
?
L-Lys-L-Ala-7-amido-4-methylcoumarin + H2O
L-Lys-L-Ala + 7-amino-4-methylcoumarin
-
-
-
-
?
Leu-Ala-2-naphthylamide + H2O
Leu-Ala + 2-naphthylamine
-
-
-
-
?
Leu-Ala-2-naphthylamide + H2O
Leu-Ala + 2-naphthylamine
-
-
-
-
?
Lys-Ala-2-(4-methoxy)-naphthylamide Lys-Ala-4-methoxy-2-naphthylamide + H2O
?
-
-
-
-
?
Lys-Ala-2-(4-methoxy)-naphthylamide Lys-Ala-4-methoxy-2-naphthylamide + H2O
?
-
-
-
-
?
Lys-Ala-2-naphthylamide + H2O
Lys-Ala + 2-naphthylamine
-
-
-
-
?
Lys-Ala-2-naphthylamide + H2O
Lys-Ala + 2-naphthylamine
-
-
-
-
?
Lys-Ala-2-naphthylamide + H2O
Lys-Ala + 2-naphthylamine
-
15% of the activity with Phe-Pro-2-naphthylamide
-
-
?
Lys-Ala-4-methylcoumaryl-7-amide + H2O
Lys-Ala + 7-amino-4-methylcoumarin
-
-
-
-
?
Lys-Ala-4-methylcoumaryl-7-amide + H2O
Lys-Ala + 7-amino-4-methylcoumarin
-
-
-
?
Lys-Ala-4-methylcoumaryl-7-amide + H2O
Lys-Ala + 7-amino-4-methylcoumarin
-
-
-
-
?
Lys-Ala-7-amido-4-methylcoumarin + H2O
Lys-Ala + 7-amino-4-methylcoumarin
-
-
?
Lys-Ala-7-amido-4-methylcoumarin + H2O
Lys-Ala + 7-amino-4-methylcoumarin
-
-
-
?
Lys-Ala-7-amido-4-methylcoumarin + H2O
Lys-Ala + 7-amino-4-methylcoumarin
-
38% activity compared to Gly-Pro-7-amido-4-methylcoumarin
-
-
?
Lys-Ala-Ala + H2O
Lys-Ala + Ala
-
-
-
-
?
Lys-Ala-Ala + H2O
Lys-Ala + Ala
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Lys-Pro-2-(4-methoxy)-naphthylamine + H2O
?
-
-
-
-
?
Lys-Pro-2-naphthylamide + H2O
Lys-Pro + 2-naphthylamine
-
-
-
-
?
Lys-Pro-2-naphthylamide + H2O
Lys-Pro + 2-naphthylamine
-
46% of the activity with Phe-Pro-2-naphthylamide
-
-
?
Lys-Pro-4-nitroanilide + H2O
Lys-Pro + 4-nitroaniline
-
-
-
-
?
Lys-Pro-4-nitroanilide + H2O
Lys-Pro + 4-nitroaniline
-
-
-
-
?
Lys-Pro-p-nitroanilide + H2O
Lys-Pro + p-nitroaniline
-
-
-
-
?
Lys-Pro-p-nitroanilide + H2O
Lys-Pro + p-nitroaniline
-
-
-
?
Phe-Pro-2-naphthylamide + H2O
Phe-Pro + 2-naphthylamine
-
-
-
-
?
Phe-Pro-2-naphthylamide + H2O
Phe-Pro + 2-naphthylamine
-
-
-
-
?
Substance P + H2O
?
-
-
-
-
?
Substance P + H2O
?
-
-
-
?
Substance P + H2O
?
-
-
-
-
?
Substance P + H2O
?
-
-
-
-
?
Val-Ala-Phe-OH + H2O
Val-Ala + Phe-OH
-
-
-
?
Val-Ala-Phe-OH + H2O
Val-Ala + Phe-OH
-
-
-
?
additional information
?
-
-
Pro and Arg are the preferred penultimate residues
-
-
?
additional information
?
-
-
no hydrolysis occurs if either the carboxyl group or the amino group of otherwise susceptible tripeptides is blocked. Tetrapeptides, tripeptide esters and dipeptides are not attacked
-
-
?
additional information
?
-
-
Ala and Pro are the preferred residues in the P1 position
-
-
?
additional information
?
-
specific for Pro at position P1
-
?
additional information
?
-
-
specific for Pro at position P1
-
?
additional information
?
-
Ala and Pro are the preferred residues in the P1 position
-
-
?
additional information
?
-
-
no activity with Ala-Ala-Ala-Ala-Ala, Arg-Pro-Lys-Pro (substance P 1-4), and Arg-Pro-Pro-Gly-Phe (bradikinin1-5)
-
-
?
additional information
?
-
-
the enzyme contributes to the alveolar macrophage's proteolytic capabilities
-
-
?
additional information
?
-
-
substrate specificity
-
?
additional information
?
-
-
no activity with bradykinin
-
-
?
additional information
?
-
-
the enzyme contributes to the alveolar macrophage's proteolytic capabilities
-
-
?
additional information
?
-
-
hydrolyzes specifically N-terminal X-alanine or X-proline from their respective arylamides and from tripeptides or tetrapeptides, but not from pentapeptides
-
-
?
additional information
?
-
-
possible role of the mast cell enzyme in remodelling of connective tissue
-
-
?
additional information
?
-
-
the enzyme may play a role in the segregation and degradation of specific regions of normal lens fiber cells
-
-
?
additional information
?
-
-
Ala and Pro are the preferred residues in the P1 position
-
-
?
additional information
?
-
-
Ala and Pro are the preferred residues in the P1 position
-
-
?
additional information
?
-
-
no activity with Gly-Arg-7-amido-4-methylcoumarin, Arg-Arg-7-amido-4-methylcoumarin, and Ala-Arg-7-amido-4-methylcoumarin
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(1R,S)-(2E)-2-(1-fluoro-2-[(2-phenylethyl)amino]ethylidene)cyclopentanecarbonitrile
-
IC50: 0.0361 mM, low inhibitory potential against EC 3.4.14.5
(1R,S)-(2E)-2-(1-fluoro-2-[(4-fluorobenzyl)amino]ethylidene)cyclopentanecarbonitrile
-
IC50: 0.0404 mM, low inhibitory potential against EC 3.4.14.5
(1R,S)-(2Z)-2-(1-fluoro-2-[(2-phenylethyl)amino]ethylidene)cyclopentanecarbonitrile
-
IC50: 0.0329 mM, low inhibitory potential against EC 3.4.14.5
(1R,S)-(2Z)-2-(1-fluoro-2-[(4-fluorobenzyl)amino]ethylidene)cyclopentanecarbonitrile
-
IC50: 0.0873 mM, low inhibitory potential against EC 3.4.14.5
(3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
-
-
(3S)-4-[(3aR,6aR)-hexahydrocyclopenta[b]pyrrol-1(2H)-yl]-4-oxobutane-1,3-diamine
-
AX8819, potent and selective inhibitor of DPP II
(3S)-N1-(4-chlorobenzyl)-4-(2-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
-
IC50: 2.3 mM; IC50: 2.3 nM
(3S)-N1-(4-chlorobenzyl)-4-(3-fluoropiperidin-1-yl)-4-oxobutane-1,3-diamine
-
0.62 nM; IC50: 0.62 nM
(3S)-N1-(4-chlorobenzyl)-4-(3-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
-
IC50: 1.13 nM
(3S)-N1-(4-chlorobenzyl)-4-(4-fluoropiperidin-1-yl)-4-oxobutane-1,3-diamine
-
IC50: 0.39 nM
(3S)-N1-(4-chlorobenzyl)-4-(4-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
-
IC50: 0.55 nM
(3S)-N1-(4-chlorobenzyl)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
(D-Ala)3
-
5 mM, 30% inhibition of hydrolysis of (L-Ala)3, noncompetitive
1-((2S)-2-amino-4-((4-chlorobenzyl)amino)butanoyl)piperidin-3-ol
-
IC50: 54.7 nM
1-((2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl)piperidin-4-ol
-
IC50: 113 nM
1-((2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl)piperidine-2-carbonitrile
-
IC50: 6.5 nM
1-([(2-phenylethyl)amino]acetyl)-2-pyrrolidinecarbonitrile
-
0.0163 mM
1-([(4-fluorobenzyl)amino]acetyl)-2-pyrrolidinecarbonitrile
-
IC50: 0.0255 mM
1-benzyl-N-(2-cyclohexylidene-2-fluoroethyl)-4-piperidinamine
-
IC50: 0.00104 mM, low inhibitory potential against EC 3.4.14.5
1-benzyl-N-(2-cyclohexylidene-2-fluoroethyl)piperidin-4-amine
-
-
1-benzyl-N-(2-cyclopentylidene-2-fluoroethyl)-4-piperidinamine
-
IC50: 0.0013 mM, low inhibitory potential against EC 3.4.14.5
1-benzyl-N-(2-oxo-2-piperidin-1-ylethyl)piperidin-4-amine
-
-
1-benzyl-N-[2-oxo-2-(1-piperidinyl)ethyl]-4-piperidinamine
-
IC50: 0.0031 mM, low inhibitory potential against EC 3.4.14.5
1-[(1-adamantylamino)acetyl]-2-pyrrolidinecarbonitrile
-
IC50: 0.1335 mM
1-[(2S)-2-amino-4-(benzylamino)butanoyl]piperidine-2-carbonitrile
-
IC50: 4.0 nM
1-[(2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl]piperidin-3-ol
-
IC50: 54.7 nM
1-[(2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl]piperidin-4-ol
-
IC50: 113 nM
1-[(2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl]piperidine-2-carbonitrile
-
IC50: 6.5 nM
3-((3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl)aminomethyl)-benzonitrile
-
IC50: 2.7 nM
4-(2-aminoethyl)benzenesulfonyl fluoride
4-Chloromercuriphenylsulfonate
4-oxo-4-(1-piperidinyl)-N1 -(4-piperidinyl)-1,3-(S)-butanedi-amine
-
IC50: 85 nM
4-oxo-4-(1-piperidinyl)-N1-(2-thienylmethyl)-1,3-(S)-butanediamine
-
IC50: 0.8 nM
4-oxo-4-(1-piperidinyl)-N1-(4-pyridinylmethyl)-1,3-(S)-butanediamine
-
IC50: 0.75 nM
4-oxo-4-(1-piperidinyl)-N3-(4-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.017 mM
4-oxo-N1-(2-phenylethyl)-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.9 nM
4-oxo-N1-(3-phenylpropyl)-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.91 nM
4-oxo-N1-phenyl-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.0015 mM
6-((3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl)amino)nicotinonitrile
-
IC50: 0.0046 mM
Ala-PSI[CS-N]-pyrrolidine
Ala-PSI[CS-N]-thiazolidine
benzamidine
-
10% inhibition at 1 mM, preincubation at room temperature for 15 min
benzethonium chloride
-
-
benzyl 4-[(2-cyclohexylidene-2-fluoroethyl)amino]-1-piperidinecarboxylate
-
IC50: 0.0128 mM, low inhibitory potential against EC 3.4.14.5
cetyltrimethylammonium bromide
-
-
diaminobutyric acid-piperidide
-
-
diisopropyl fluorophosphate
diisopropylfluorophosphate
-
complete inhibition at 1 mM, 25% inhibition at 0.1 mM, preincubation at room temperature for 15 min
Diprotin A
not selective for the enzyme
epsilon-Z-Lys-Pro
-
competitive inhibitor
Fe2+
-
significant inhibition
Ile cyanothiazolidide
not selective for the enzyme
Ile-PSI[CS-N]-pyrrolidine
Ile-PSI[CS-N]-thiazolidine
Lys piperidide
not selective for the enzyme
Lys thiazolidide
not selective for the enzyme
Lys-Ala chloromethyl ketone
-
0.1 mM, complete inhibition, active-site-directed inhibitor
Lys-Ala-CH2Cl
-
inhibitory at 0.1 mM
N-(1,3-benzodioxol-5-ylmethyl)-2-cyclohexylidene-2-fluoroethanamine
-
IC50: 0.0129 mM, low inhibitory potential against EC 3.4.14.5
N-(1,3-benzodioxol-5-ylmethyl)-2-cyclopentylideneethanamine
-
0.0075 mM; IC50: 0.0075 mM, low inhibitory potential against EC 3.4.14.5, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)-1-adamantanamine
-
IC50: 0.0913 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)-4-piperidinamine
-
IC50: 0.0042 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)-N-(2-phenylethyl)-amine
-
IC50: 0.011 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)-N-(4-fluorobenzyl)-amine
-
IC50: 0.0219 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)-N-(4-methoxybenzyl)amine
-
IC50: 0.0134 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)aniline
-
IC50: 0.1 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclohexylidene-2-fluoroethyl)cyclohexanamine
-
IC50: 0.5 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclopentylidene-2-fluoroethyl)-N-(2-phenylethyl)amine
-
IC50: 0.0272 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclopentylidene-2-fluoroethyl)-N-(2-pyridinylethyl)amine
-
IC50: 0.0096 mM, low inhibitory potential against EC 3.4.14.5; IC50: 0.0157 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclopentylidene-2-fluoroethyl)-N-(4-fluorobenzyl)amine
-
IC50: 0.0108 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclopentylidene-2-fluoroethyl)-N-(4-methoxy-benzyl)amine
-
IC50: 0.0155 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclopentylidene-2-fluoroethyl)cyclohexanamine
-
IC50: 0.09 mM, low inhibitory potential against EC 3.4.14.5
N-(2-cyclopentylideneethyl)cyclohexanamine
-
IC50: 0.062 mM; IC50: 0.062 mM, low inhibitory potential against EC 3.4.14.5, low inhibitory potential against EC 3.4.14.5
N-(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butane-diamine dihydrochloride
N-4(chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine dihydrochloride
-
-
N-benzyl-2-cyclohexylidene-2-fluoroethanamine
-
IC50: 0.034 mM, low inhibitory potential against EC 3.4.14.5
N-benzyl-2-cyclopentylidene-2-fluoroethanamine
-
IC50: 0.0378 mM, low inhibitory potential against EC 3.4.14.5
N-benzyl-2-cyclopentylideneethanamine
-
IC50: 0.026 mM; IC50: 0.026 mM, low inhibitory potential against EC 3.4.14.5, low inhibitory potential against EC 3.4.14.5
N-benzyl-2-oxo-2-(1-piperidinyl)ethaneamine
-
IC50: 0.397 mM, low inhibitory potential against EC 3.4.14.5
N-benzyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine
-
IC50: 0.5 mM
N-benzyl-2-thioxo-2-(1-piperidinyl)ethaneamine
-
IC50: 0.0484 mM, low inhibitory potential against EC 3.4.14.5
N-cyclohexyl-2-oxo-2-(1-piperidinyl)ethaneamine
-
IC50: 0.177 mM, low inhibitory potential against EC 3.4.14.5
N-cyclohexyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine
-
IC50: 0.276 mM
N-cyclohexyl-2-thioxo-2-(1-piperidinyl)ethaneamine
-
IC50: 0.069 mM, low inhibitory potential against EC 3.4.14.5
N-cyclohexyl-2-thioxo-2-(1-pyrrolidinyl)ethaneamine
-
IC50: 0.092 mM, low inhibitory potential against EC 3.4.14.5
N-piperonyl-2-oxo-2-(1-piperidinyl)ethaneamine
-
IC50: 0.052 mM, low inhibitory potential against EC 3.4.14.5
N-piperonyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine
-
IC50: 0.063 mM, low inhibitory potential against EC 3.4.14.5
N-piperonyl-2-thioxo-2-(1-piperidinyl)ethaneamine
-
IC50: 0.042 mM, low inhibitory potential against EC 3.4.14.5
N-piperonyl-2-thioxo-2-(1-pyrrolidinyl)ethaneamine
-
IC50: 0.067 mM, low inhibitory potential against EC 3.4.14.5
N-[3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl]acetamide
-
IC50: 0.0015 mM
N-[3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl]guanidine bis-(trifluoroacetate)
-
IC50: 0.0018 mM
N-[3-amino-1-(S)-(1-piperidinylcarbonyl)propyl]guanidine bis-(trifluoroacetate)
-
IC50: 0.0074 mM
N-[3-amino-4-oxo-4-(1-piperidinyl)butyl]benzamide
-
IC50: 0.0074 mM
N1 -(2-cyclopentylidene-2-fluoroethyl)-N3,N3-dimethyl-1,3-propanediamine
-
IC50: 0.0537 mM, low inhibitory potential against EC 3.4.14.5
N1 -(4-methoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.66 nM
N1,N1-di(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 4.2 nM
N1,N1-dibenzyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.6 nM
N1-(1-naphthylmethyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.31 nM
N1-(2,4-dimethoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 2.7 nM
N1-(2-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.23 nM
N1-(2-cyclohexylidene-2-fluoroethyl)-N3,N3-dimethyl-1,3-propanediamine
-
IC50: 0.0546 mM, low inhibitory potential against EC 3.4.14.5
N1-(2-methoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.85 nM
N1-(2-naphthylmethyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.1 nM
N1-(3-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.34 nM
N1-(3-methoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.77 nM
N1-(3-nitro-2-pyridinyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.0235 mM
N1-(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.48 nM
N1-(4-chlorobenzyl)-N1-methyl-4-oxo-4-(1-piperidinyl)-1,3-butanediamine
-
IC50: 0.22 nm
N1-(cyclohexylmethyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 1.1 nM
N1-benzyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 2.03 nM
N1-cyclohexyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 18.6 nM
N1-[2-(benzyloxy)benzyl]-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.39 nM
N1-[4-(benzyloxy)benzyl]-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
-
IC50: 0.41 nM
N2-cyclopentyl-N-[(diphenoxyphosphoryl)(phenyl)methyl]glycinamide
-
-
N3-benzyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine dihydrobromide
-
IC50: 0.0125 mM
N6-benzyloxycarbonyl-Lys-Pro
-
1 mM, 31% inhibition of DPP II-S, 41% inhibition of DPP II-M
p-hydroxymercuribenzoate
-
-
p-Nitrophenyl-p-guanidinobenzoate
PCMBS
-
77% inhibition at 1 mM, preincubation at room temperature for 15 min
pepstatin
-
0.01 mM, 11% inhibition
Phe-PSI[CS-N]-pyrrolidine
Phe-PSI[CS-N]-thiazolidine
phenylmethylsulfonyl fluoride
Phenylmethylsulfonylfluoride
-
-
PMSF
-
45% inhibition at 1 mM, preincubation at room temperature for 15 min
puromycin aminonucleoside
-
inhibition by cations increases with the size of the ion
threo-Ile thiazolidide
not selective for the enzyme
Val pyrrolidide
not selective for the enzyme
Val thiazolidide
not selective for the enzyme
Val-PSI[CS-N]-pyrrolidine
Val-PSI[CS-N]-thiazolidine
[(1R)-1-[[(2S)-2,4-diaminobutanoyl]amino]pentyl]boronic acid
-
-
(3S)-N1-(4-chlorobenzyl)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
-
IC50: 1.1 nM
(3S)-N1-(4-chlorobenzyl)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
-
UAMC00039, potent and specific inhibitor
4-(2-aminoethyl)benzenesulfonyl fluoride
-
60% inhibition at 1 mM, preincubation at room temperature for 15 min
4-(2-aminoethyl)benzenesulfonyl fluoride
-
-
4-Chloromercuriphenylsulfonate
-
-
4-Chloromercuriphenylsulfonate
-
-
Ala-PSI[CS-N]-pyrrolidine
-
competitive
Ala-PSI[CS-N]-pyrrolidine
-
competitive
Ala-PSI[CS-N]-thiazolidine
-
competitive
Ala-PSI[CS-N]-thiazolidine
-
competitive
Ala-pyrrolidine
-
competitive
Ala-pyrrolidine
-
competitive
Ala-thiazolidine
-
competitive
Ala-thiazolidine
-
competitive
bestatin
-
-
bestatin
-
1 mM, 12% inhibition of DPP II-S, 21% inhibition of DPP II-M; no inhibition
Cd2+
-
moderate inhibition
Co2+
-
moderate inhibition
Cu2+
-
significant inhibition
Cu2+
-
10 mM CuSO4, 23% inhibition
Cu2+
-
40% inhibition at 1 mM, preincubation at room temperature for 15 min
diisopropyl fluorophosphate
-
-
diisopropyl fluorophosphate
-
-
diisopropyl fluorophosphate
-
-
diisopropyl fluorophosphate
-
-
Hg2+
-
significant inhibition
Hg2+
-
complete inhibition at 1 mM, preincubation at room temperature for 15 min
histamine
-
-
histamine
-
0.1 M 55% inhibition
Ile-PSI[CS-N]-pyrrolidine
-
competitive
Ile-PSI[CS-N]-pyrrolidine
-
competitive
Ile-PSI[CS-N]-thiazolidine
-
competitive
Ile-PSI[CS-N]-thiazolidine
-
competitive
Ile-pyrrolidine
-
competitive
Ile-pyrrolidine
-
competitive
Ile-thiazolidine
-
competitive
Ile-thiazolidine
-
competitive
iodoacetate
-
-
K+
-
-
K+
-
inhibition by cations increases with the size of the ion
K+
-
50 mM KCl, 42% inhibition
Li+
-
-
Li+
-
inhibition by cations increases with the size of the ion
lysyl-piperidide
-
-
N-(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butane-diamine dihydrochloride
-
N-(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butane-diamine dihydrochloride
-
-
Na+
-
-
Na+
-
inhibition by cations increases with the size of the ion
Na+
-
10 mM NaCl, 38% inhibition
Na+
-
400 mM NaCl, 56% inhibition of DPP II-M, 31% inhibition of DPP II-S
Na+
-
100 mM NaCl, 11% inhibition
p-Nitrophenyl-p-guanidinobenzoate
-
-
p-Nitrophenyl-p-guanidinobenzoate
-
1 mM, 43% inhibition
p-Nitrophenyl-p-guanidinobenzoate
-
-
Pb2+
-
moderate inhibition
Phe-PSI[CS-N]-pyrrolidine
-
competitive
Phe-PSI[CS-N]-pyrrolidine
-
competitive
Phe-PSI[CS-N]-thiazolidine
-
competitive
Phe-PSI[CS-N]-thiazolidine
-
competitive
Phe-pyrrolidine
-
competitive
Phe-pyrrolidine
-
competitive
Phe-thiazolidine
-
competitive
Phe-thiazolidine
-
competitive
phenylmethylsulfonyl fluoride
-
1 mM, 15% inhibition
phenylmethylsulfonyl fluoride
-
-
phenylmethylsulfonyl fluoride
-
5 mM, about 80% inhibition
phenylmethylsulfonyl fluoride
-
-
phenylmethylsulfonyl fluoride
-
-
phenylmethylsulfonyl fluoride
-
-
puromycin
-
-
puromycin
-
1 mM, 76% inhibition; inhibition by cations increases with the size of the ion
puromycin
-
1 mM, 47% inhibition
sodium deoxycholate
-
-
Tris
-
-
Tris
-
50 mM, 96% inhibition; inhibition by cations increases with the size of the ion
Tris
-
50 mM, 97% inhibition
Tris
-
50 mM, 55% inhibition
Val-PSI[CS-N]-pyrrolidine
-
competitive
Val-PSI[CS-N]-pyrrolidine
-
competitive
Val-PSI[CS-N]-thiazolidine
-
competitive
Val-PSI[CS-N]-thiazolidine
-
competitive
Val-pyrrolidine
-
competitive
Val-pyrrolidine
-
competitive
Val-thiazolidine
-
competitive
Val-thiazolidine
-
competitive
Zn2+
-
moderate inhibition
Zn2+
-
10 mM, 83% inhibition
additional information
-
not inhibited by N-ethylmaleimide, p-chloromercuribenzoate, iodoacetate, iodoacetamide, beta-mercaptoethanol, cysteine, EDTA, EGTA, o-phenanthroline, or dithiothreitol
-
additional information
-
isomerization of the thiazolidine derivatives
-
additional information
-
poor or no inhibition by EDTA, NEM, E-64, diprotin A, and actinonin
-
additional information
-
no inhibition by bacitracin
-
additional information
-
isomerization of the thiazolidine derivatives
-
additional information
-
not inhibited by diprotin A
-
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0.0361
(1R,S)-(2E)-2-(1-fluoro-2-[(2-phenylethyl)amino]ethylidene)cyclopentanecarbonitrile
Homo sapiens
-
IC50: 0.0361 mM, low inhibitory potential against EC 3.4.14.5
0.0404
(1R,S)-(2E)-2-(1-fluoro-2-[(4-fluorobenzyl)amino]ethylidene)cyclopentanecarbonitrile
Homo sapiens
-
IC50: 0.0404 mM, low inhibitory potential against EC 3.4.14.5
0.0329
(1R,S)-(2Z)-2-(1-fluoro-2-[(2-phenylethyl)amino]ethylidene)cyclopentanecarbonitrile
Homo sapiens
-
IC50: 0.0329 mM, low inhibitory potential against EC 3.4.14.5
0.0873
(1R,S)-(2Z)-2-(1-fluoro-2-[(4-fluorobenzyl)amino]ethylidene)cyclopentanecarbonitrile
Homo sapiens
-
IC50: 0.0873 mM, low inhibitory potential against EC 3.4.14.5
0.00013
(3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
Homo sapiens
-
-
0.00000088
(3S)-4-[(3aR,6aR)-hexahydrocyclopenta[b]pyrrol-1(2H)-yl]-4-oxobutane-1,3-diamine
Homo sapiens
-
-
0.0000023 - 2.3
(3S)-N1-(4-chlorobenzyl)-4-(2-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
0.62
(3S)-N1-(4-chlorobenzyl)-4-(3-fluoropiperidin-1-yl)-4-oxobutane-1,3-diamine
Homo sapiens
-
IC50: 0.62 nM
0.00000113
(3S)-N1-(4-chlorobenzyl)-4-(3-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
Homo sapiens
-
IC50: 1.13 nM
0.00000039
(3S)-N1-(4-chlorobenzyl)-4-(4-fluoropiperidin-1-yl)-4-oxobutane-1,3-diamine
Homo sapiens
-
IC50: 0.39 nM
0.00000055
(3S)-N1-(4-chlorobenzyl)-4-(4-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
Homo sapiens
-
IC50: 0.55 nM
0.00000048 - 0.0000011
(3S)-N1-(4-chlorobenzyl)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
0.0000547
1-((2S)-2-amino-4-((4-chlorobenzyl)amino)butanoyl)piperidin-3-ol
Homo sapiens
-
IC50: 54.7 nM
0.000113
1-((2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl)piperidin-4-ol
Homo sapiens
-
IC50: 113 nM
0.0000065
1-((2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl)piperidine-2-carbonitrile
Homo sapiens
-
IC50: 6.5 nM
0.0255
1-([(4-fluorobenzyl)amino]acetyl)-2-pyrrolidinecarbonitrile
Homo sapiens
-
IC50: 0.0255 mM
0.00104
1-benzyl-N-(2-cyclohexylidene-2-fluoroethyl)-4-piperidinamine
Homo sapiens
-
IC50: 0.00104 mM, low inhibitory potential against EC 3.4.14.5
0.00104
1-benzyl-N-(2-cyclohexylidene-2-fluoroethyl)piperidin-4-amine
Homo sapiens
-
-
0.0013
1-benzyl-N-(2-cyclopentylidene-2-fluoroethyl)-4-piperidinamine
Homo sapiens
-
IC50: 0.0013 mM, low inhibitory potential against EC 3.4.14.5
0.0031
1-benzyl-N-(2-oxo-2-piperidin-1-ylethyl)piperidin-4-amine
Homo sapiens
-
-
0.0031
1-benzyl-N-[2-oxo-2-(1-piperidinyl)ethyl]-4-piperidinamine
Homo sapiens
-
IC50: 0.0031 mM, low inhibitory potential against EC 3.4.14.5
0.1335
1-[(1-adamantylamino)acetyl]-2-pyrrolidinecarbonitrile
Homo sapiens
-
IC50: 0.1335 mM
0.000004
1-[(2S)-2-amino-4-(benzylamino)butanoyl]piperidine-2-carbonitrile
Homo sapiens
-
IC50: 4.0 nM
0.0000547
1-[(2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl]piperidin-3-ol
Homo sapiens
-
IC50: 54.7 nM
0.000113
1-[(2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl]piperidin-4-ol
Homo sapiens
-
IC50: 113 nM
0.0000065
1-[(2S)-2-amino-4-[(4-chlorobenzyl)amino]butanoyl]piperidine-2-carbonitrile
Homo sapiens
-
IC50: 6.5 nM
0.0000027
3-((3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl)aminomethyl)-benzonitrile
Homo sapiens
-
IC50: 2.7 nM
0.000085
4-oxo-4-(1-piperidinyl)-N1 -(4-piperidinyl)-1,3-(S)-butanedi-amine
Homo sapiens
-
IC50: 85 nM
0.0000008
4-oxo-4-(1-piperidinyl)-N1-(2-thienylmethyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.8 nM
0.00000075
4-oxo-4-(1-piperidinyl)-N1-(4-pyridinylmethyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.75 nM
0.017
4-oxo-4-(1-piperidinyl)-N3-(4-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.017 mM
0.0000009
4-oxo-N1-(2-phenylethyl)-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.9 nM
0.00000191
4-oxo-N1-(3-phenylpropyl)-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.91 nM
0.0015
4-oxo-N1-phenyl-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.0015 mM
0.0046
6-((3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl)amino)nicotinonitrile
Homo sapiens
-
IC50: 0.0046 mM
0.0128
benzyl 4-[(2-cyclohexylidene-2-fluoroethyl)amino]-1-piperidinecarboxylate
Homo sapiens
-
IC50: 0.0128 mM, low inhibitory potential against EC 3.4.14.5
0.0129
N-(1,3-benzodioxol-5-ylmethyl)-2-cyclohexylidene-2-fluoroethanamine
Homo sapiens
-
IC50: 0.0129 mM, low inhibitory potential against EC 3.4.14.5
0.0075
N-(1,3-benzodioxol-5-ylmethyl)-2-cyclopentylideneethanamine
Homo sapiens
-
IC50: 0.0075 mM, low inhibitory potential against EC 3.4.14.5, low inhibitory potential against EC 3.4.14.5
0.0913
N-(2-cyclohexylidene-2-fluoroethyl)-1-adamantanamine
Homo sapiens
-
IC50: 0.0913 mM, low inhibitory potential against EC 3.4.14.5
0.0042
N-(2-cyclohexylidene-2-fluoroethyl)-4-piperidinamine
Homo sapiens
-
IC50: 0.0042 mM, low inhibitory potential against EC 3.4.14.5
0.011
N-(2-cyclohexylidene-2-fluoroethyl)-N-(2-phenylethyl)-amine
Homo sapiens
-
IC50: 0.011 mM, low inhibitory potential against EC 3.4.14.5
0.0219
N-(2-cyclohexylidene-2-fluoroethyl)-N-(4-fluorobenzyl)-amine
Homo sapiens
-
IC50: 0.0219 mM, low inhibitory potential against EC 3.4.14.5
0.0134
N-(2-cyclohexylidene-2-fluoroethyl)-N-(4-methoxybenzyl)amine
Homo sapiens
-
IC50: 0.0134 mM, low inhibitory potential against EC 3.4.14.5
0.1
N-(2-cyclohexylidene-2-fluoroethyl)aniline
Homo sapiens
-
IC50: 0.1 mM, low inhibitory potential against EC 3.4.14.5
0.5
N-(2-cyclohexylidene-2-fluoroethyl)cyclohexanamine
Homo sapiens
-
IC50: 0.5 mM, low inhibitory potential against EC 3.4.14.5
0.0272
N-(2-cyclopentylidene-2-fluoroethyl)-N-(2-phenylethyl)amine
Homo sapiens
-
IC50: 0.0272 mM, low inhibitory potential against EC 3.4.14.5
0.0096 - 0.0157
N-(2-cyclopentylidene-2-fluoroethyl)-N-(2-pyridinylethyl)amine
0.0108
N-(2-cyclopentylidene-2-fluoroethyl)-N-(4-fluorobenzyl)amine
Homo sapiens
-
IC50: 0.0108 mM, low inhibitory potential against EC 3.4.14.5
0.0155
N-(2-cyclopentylidene-2-fluoroethyl)-N-(4-methoxy-benzyl)amine
Homo sapiens
-
IC50: 0.0155 mM, low inhibitory potential against EC 3.4.14.5
0.09
N-(2-cyclopentylidene-2-fluoroethyl)cyclohexanamine
Homo sapiens
-
IC50: 0.09 mM, low inhibitory potential against EC 3.4.14.5
0.062
N-(2-cyclopentylideneethyl)cyclohexanamine
0.034
N-benzyl-2-cyclohexylidene-2-fluoroethanamine
Homo sapiens
-
IC50: 0.034 mM, low inhibitory potential against EC 3.4.14.5
0.0378
N-benzyl-2-cyclopentylidene-2-fluoroethanamine
Homo sapiens
-
IC50: 0.0378 mM, low inhibitory potential against EC 3.4.14.5
0.026
N-benzyl-2-cyclopentylideneethanamine
0.397
N-benzyl-2-oxo-2-(1-piperidinyl)ethaneamine
Homo sapiens
-
IC50: 0.397 mM, low inhibitory potential against EC 3.4.14.5
0.5
N-benzyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine
Homo sapiens
-
IC50: 0.5 mM
0.0484
N-benzyl-2-thioxo-2-(1-piperidinyl)ethaneamine
Homo sapiens
-
IC50: 0.0484 mM, low inhibitory potential against EC 3.4.14.5
0.177
N-cyclohexyl-2-oxo-2-(1-piperidinyl)ethaneamine
Homo sapiens
-
IC50: 0.177 mM, low inhibitory potential against EC 3.4.14.5
0.276
N-cyclohexyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine
Homo sapiens
-
IC50: 0.276 mM
0.069
N-cyclohexyl-2-thioxo-2-(1-piperidinyl)ethaneamine
Homo sapiens
-
IC50: 0.069 mM, low inhibitory potential against EC 3.4.14.5
0.092
N-cyclohexyl-2-thioxo-2-(1-pyrrolidinyl)ethaneamine
Homo sapiens
-
IC50: 0.092 mM, low inhibitory potential against EC 3.4.14.5
0.052
N-piperonyl-2-oxo-2-(1-piperidinyl)ethaneamine
Homo sapiens
-
IC50: 0.052 mM, low inhibitory potential against EC 3.4.14.5
0.063
N-piperonyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine
Homo sapiens
-
IC50: 0.063 mM, low inhibitory potential against EC 3.4.14.5
0.042
N-piperonyl-2-thioxo-2-(1-piperidinyl)ethaneamine
Homo sapiens
-
IC50: 0.042 mM, low inhibitory potential against EC 3.4.14.5
0.067
N-piperonyl-2-thioxo-2-(1-pyrrolidinyl)ethaneamine
Homo sapiens
-
IC50: 0.067 mM, low inhibitory potential against EC 3.4.14.5
0.0015
N-[3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl]acetamide
Homo sapiens
-
IC50: 0.0015 mM
0.0018
N-[3-(S)-amino-4-oxo-4-(1-piperidinyl)butyl]guanidine bis-(trifluoroacetate)
Homo sapiens
-
IC50: 0.0018 mM
0.0074
N-[3-amino-1-(S)-(1-piperidinylcarbonyl)propyl]guanidine bis-(trifluoroacetate)
Homo sapiens
-
IC50: 0.0074 mM
0.0074
N-[3-amino-4-oxo-4-(1-piperidinyl)butyl]benzamide
Homo sapiens
-
IC50: 0.0074 mM
0.0537
N1 -(2-cyclopentylidene-2-fluoroethyl)-N3,N3-dimethyl-1,3-propanediamine
Homo sapiens
-
IC50: 0.0537 mM, low inhibitory potential against EC 3.4.14.5
0.00000066
N1 -(4-methoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.66 nM
0.0000042
N1,N1-di(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 4.2 nM
0.0000006
N1,N1-dibenzyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.6 nM
0.00000131
N1-(1-naphthylmethyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.31 nM
0.0000027
N1-(2,4-dimethoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 2.7 nM
0.00000023
N1-(2-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.23 nM
0.0546
N1-(2-cyclohexylidene-2-fluoroethyl)-N3,N3-dimethyl-1,3-propanediamine
Homo sapiens
-
IC50: 0.0546 mM, low inhibitory potential against EC 3.4.14.5
0.00000185
N1-(2-methoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.85 nM
0.0000011
N1-(2-naphthylmethyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.1 nM
0.00000134
N1-(3-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.34 nM
0.00000177
N1-(3-methoxybenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.77 nM
0.0235
N1-(3-nitro-2-pyridinyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.0235 mM
0.00000048
N1-(4-chlorobenzyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.48 nM
0.00000022
N1-(4-chlorobenzyl)-N1-methyl-4-oxo-4-(1-piperidinyl)-1,3-butanediamine
Homo sapiens
-
IC50: 0.22 nm
0.0000011
N1-(cyclohexylmethyl)-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 1.1 nM
0.00000203
N1-benzyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 2.03 nM
0.0000186
N1-cyclohexyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 18.6 nM
0.00000039
N1-[2-(benzyloxy)benzyl]-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.39 nM
0.00000041
N1-[4-(benzyloxy)benzyl]-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine
Homo sapiens
-
IC50: 0.41 nM
0.0038
N2-cyclopentyl-N-[(diphenoxyphosphoryl)(phenyl)methyl]glycinamide
Homo sapiens
-
-
0.0125
N3-benzyl-4-oxo-4-(1-piperidinyl)-1,3-(S)-butanediamine dihydrobromide
Homo sapiens
-
IC50: 0.0125 mM
0.00000048
[(1R)-1-[[(2S)-2,4-diaminobutanoyl]amino]pentyl]boronic acid
Homo sapiens
-
-
0.0000023
(3S)-N1-(4-chlorobenzyl)-4-(2-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
Homo sapiens
-
IC50: 2.3 nM
2.3
(3S)-N1-(4-chlorobenzyl)-4-(2-methylpiperidin-1-yl)-4-oxobutane-1,3-diamine
Homo sapiens
-
IC50: 2.3 mM
0.00000048
(3S)-N1-(4-chlorobenzyl)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
Homo sapiens
-
-
0.0000011
(3S)-N1-(4-chlorobenzyl)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
Homo sapiens
-
IC50: 1.1 nM
0.0096
N-(2-cyclopentylidene-2-fluoroethyl)-N-(2-pyridinylethyl)amine
Homo sapiens
-
IC50: 0.0096 mM, low inhibitory potential against EC 3.4.14.5
0.0157
N-(2-cyclopentylidene-2-fluoroethyl)-N-(2-pyridinylethyl)amine
Homo sapiens
-
IC50: 0.0157 mM, low inhibitory potential against EC 3.4.14.5
0.062
N-(2-cyclopentylideneethyl)cyclohexanamine
Homo sapiens
-
IC50: 0.062 mM
0.062
N-(2-cyclopentylideneethyl)cyclohexanamine
Homo sapiens
-
IC50: 0.062 mM, low inhibitory potential against EC 3.4.14.5, low inhibitory potential against EC 3.4.14.5
0.026
N-benzyl-2-cyclopentylideneethanamine
Homo sapiens
-
IC50: 0.026 mM
0.026
N-benzyl-2-cyclopentylideneethanamine
Homo sapiens
-
IC50: 0.026 mM, low inhibitory potential against EC 3.4.14.5, low inhibitory potential against EC 3.4.14.5
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Mantle, D.
Characterization of dipeptidyl and tripeptidyl aminopeptidases in human kidney soluble fraction
Clin. Chim. Acta
196
135-142
1991
Homo sapiens
brenda
Chan, S.A.T.; Toursarkissian, K.; Sweeny, J.P.; Jones, T.H.D.
Dipeptidyl-aminopeptidases and aminopeptidases in Dictyostelium discoideum
Biochem. Biophys. Res. Commun.
127
962-968
1985
Dictyostelium discoideum
brenda
Alba, F.; Arenas, J.C.; Lopez, M.A.
Properties of rat brain dipeptidyl aminopeptidases in the presence of detergents
Peptides
16
325-329
1995
Rattus norvegicus
brenda
Lynn, K.R.
The isolation and some properties of dipeptidyl peptidases II and III from porcine spleen
Int. J. Biochem.
23
47-50
1991
Sus scrofa
brenda
MacFarlane, S.; MacFarlane, G.T.
Formation of a dipeptidyl arylamidase by Bacteroides splanchnicus NCTC 10825 with specificities towards glycylprolyl-x and valylalanine-x substrates
J. Med. Microbiol.
46
547-555
1997
Odoribacter splanchnicus
brenda
Mentlein, R.; Struckhoff, G.
Purification of two dipeptidyl aminopeptidases II from rat brain and their action on proline-containing neuropeptides
J. Neurochem.
52
1284-1293
1989
Rattus norvegicus
brenda
Sakai, T.; Kojima, K.
Rapid chromatographic purification of dipeptidyl-aminopeptidase II from human kidney
J. Chromatogr.
416
131-137
1987
Homo sapiens
brenda
DiCarlantonio, G.; Talbot, P.; Dudenhausen, E.
Partial purification and characterization of dipeptidyl peptidase II (DPP II) from guinea pig testes
Gamete Res.
15
161-175
1986
Cavia porcellus
-
brenda
Eisenhauer, D.A.; McDonald, J.K.
A novel dipeptidyl peptidase II from the porcine ovary. Purification and characterization of a lysosomal serine protease showing enhanced specificity for prolyl bonds
J. Biol. Chem.
261
8859-8865
1986
Sus scrofa
brenda
Struckhoff, G.; Heymann, E.
Rat peritoneal mast cells release dipeptidyl peptidase II
Biochem. J.
236
215-219
1986
Rattus norvegicus
brenda
McDonald, J.K.; Eisenhauer, D.A.; Hoisington, A.R.
Complementary specificities of ovarian dipeptidyl peptidase II and tripeptidyl peptidase: collagenolytic potential and increased activity associated with ovulation in the hog
Prog. Clin. Biol. Res.
180
673-675
1985
Sus scrofa
brenda
Nagatsu, T.; Sakai, T.; Kojima, K.; Araki, E.; Sakakibara, S.; Fukasawa, K.; Harada, M.
A sensitive and specific assay for dipeptidyl-aminopeptidase II in serum and tissues by liquid chromatography-fluorometry
Anal. Biochem.
147
80-85
1985
Homo sapiens
brenda
Fukasawa, K.; Fukasawa, K.M.; Hiraoka, B.Y.; Harada, M.
Purification and properties of dipeptidyl peptidase II from rat kidney
Biochim. Biophys. Acta
745
6-11
1983
Rattus norvegicus
brenda
McDonald, J.K.; Schwabe, C.
Dipeptidyl peptidase II of bovine dental pulp. Initial demonstration and characterization as a fibroblastic, lysosomal peptidase of the serine class active on collagen-related peptides
Biochim. Biophys. Acta
616
68-81
1980
Bos taurus
brenda
Gossrau, R.; Lojda, Z.
Study on dipeptidylpeptidase II (DPP II)
Histochemistry
70
53-76
1980
Cavia porcellus, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
McDonald, J.K.; Reilly, T.J.; Zeitman, B.B.; Ellis, S.
Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization
J. Biol. Chem.
243
2028-2037
1968
Bos taurus, Rattus norvegicus
brenda
McDonald, J.K.; Leibach, F.H.; Grindeland, R.E.; Ellis, S.
Purification of dipeptidyl aminopeptidase II (dipeptidyl arylamidase II) of the anterior pituitary gland
J. Biol. Chem.
243
4143-4150
1968
Bos taurus
brenda
Sannes, P.L.
Subcellular localization of dipeptidyl peptidases II and IV in rat and rabbit alveolar macrophages
J. Histochem. Cytochem.
31
684-690
1983
Oryctolagus cuniculus, Rattus norvegicus
brenda
Huang, K.; Takagaki, M.; Kani, K.; Ohkubo, I.
Dipeptidyl peptidase II from porcine seminal plasma: purification, characterization, and its homology to granzymes, cytosolic cell proteinases (CCP 1-4)
Biochim. Biophys. Acta
1290
149-156
1996
Sus scrofa
brenda
Murao, S.; Kitade, T.; Oyama, H.; Shin, T.
Isolation and characterization of a dipeptidyl aminopeptidase from Streptomyces sp. WM-23
Biosci. Biotechnol. Biochem.
58
1545-1546
1994
Streptomyces sp., Streptomyces sp. WM-23
brenda
Gorthy, W.C.; Steward, D.E.; McDonald, J.K.
Localization of the lysosomal protease dipeptidyl peptidase II in the young normal rat lens: a correlative light and electron microscopic analysis
Curr. Eye Res.
11
531-542
1992
Rattus norvegicus
brenda
Leiting, B.; Pryor, K.D.; Wu, J.K.; Marsilio, F.; Patel, R.A.; Craik, C.S.; Ellman, J.A.; Cummings, R.T.; Thornberry, N.A.
Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII
Biochem. J.
371
525-532
2003
Homo sapiens (Q9UHL4), Homo sapiens
brenda
Stoeckel-Maschek, A.; Mrestani-Klaus, C.; Stiebitz, B.; Demuth, H.U.; Neubert, K.
Thioxo amino acid pyrrolidides and thiazolidides: new inhibitors of proline specific peptidases
Biochim. Biophys. Acta
1479
15-31
2000
Homo sapiens, Sus scrofa
brenda
Dikov, A.; Dimitrova, M.; Pajpanova, T.; Krieg, R.; Halbhuber, K.J.
Histochemical method for dipeptidyl aminopeptidase II with a new anthraquinonyl hydrazide substrate
Cell. Mol. Biol.
46
1213-1218
2000
Rattus norvegicus
brenda
Araki, H.; Li, Y.; Yamamoto, Y.; Haneda, M.; Nishi, K.; Kikkawa, R.; Ohkubo, I.
Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase
J. Biochem.
129
279-288
2001
Rattus norvegicus
brenda
Sohar, N.; Sohar, I.; Hammer, H.
Lysosomal enzyme activities: new potential markers for Sjoegrens syndrome
Clin. Biochem.
38
1120-1126
2005
Homo sapiens
brenda
Maes, M.B.; Lambeir, A.M.; Gilany, K.; Senten, K.; Van der Veken, P.; Leiting, B.; Augustyns, K.; Scharpe, S.; De Meester, I.
Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)
Biochem. J.
386
315-324
2005
Homo sapiens (Q9UHL4), Homo sapiens
brenda
Maes, M.B.; Martinet, W.; Schrijvers, D.M.; Van der Veken, P.; De Meyer, G.R.; Augustyns, K.; Lambeir, A.M.; Scharpe, S.; De Meester, I.
Dipeptidyl peptidase II and leukocyte cell death
Biochem. Pharmacol.
72
70-79
2006
Homo sapiens
brenda
Senten, K.; van der Veken, P.; De Meester, I.; Lambeir, A.M.; Scharpe, S.; Haemers, A.; Augustyns, K.
gamma-Amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors
J. Med. Chem.
47
2906-2916
2004
Homo sapiens
brenda
Van der Veken, P.; Senten, K.; Kertesz, I.; De Meester, I.; Lambeir, A.M.; Maes, M.B.; Scharpe, S.; Haemers, A.; Augustyns, K.
Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases
J. Med. Chem.
48
1768-1780
2005
Homo sapiens
brenda
Danilova, O.; Li, B.; Szardenings, A.K.; Huber, B.T.; Rosenblum, J.S.
Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor
Bioorg. Med. Chem. Lett.
17
507-510
2007
Homo sapiens
brenda
Chen, D.; Kennedy, A.; Wang, J.Y.; Zeng, W.; Zhao, Q.; Pearl, M.; Zhang, M.; Suo, Z.; Nesland, J.M.; Qiao, Y.; Ng, A.K.; Hirashima, N.; Yamane, T.; Mori, Y.; Mitsumata, M.; Ghersi, G.; Chen, W.T.
Activation of EDTA-resistant gelatinases in malignant human tumors
Cancer Res.
66
9977-9985
2006
Homo sapiens
brenda
Maes, M.B.; Scharpe, S.; De Meester, I.
Dipeptidyl peptidase II (DPPII), a review
Clin. Chim. Acta
380
31-49
2007
Bos taurus, Rattus norvegicus, Sus scrofa, Homo sapiens (Q9UHL4)
brenda
Van der Veken, P.; Haemers, A.; Augustyns, K.
Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery
Curr. Top. Med. Chem.
7
621-635
2007
Homo sapiens
brenda
Sentandreu, M.A.; Toldra, F.
Oligopeptides hydrolysed by muscle dipeptidyl peptidases can generate angiotensin-I converting enzyme inhibitory dipeptides
Eur. Food Res. Technol.
224
785-790
2007
Homo sapiens
brenda
Sentandreu, M.A.; Toldra, F.
Evaluation of ACE inhibitory activity of dipeptides generated by the action of porcine muscle dipeptidyl peptidases
Food Chem.
102
511-515
2007
Sus scrofa
brenda
Sharoyan, S.G.; Antonyan, A.A.; Mardanyan, S.S.; Lupidi, G.; Cuccioloni, M.; Angeletti, M.; Cristalli, G.
Complex of dipeptidyl peptidase II with adenosine deaminase
Biochemistry
73
943-949
2008
Bos taurus
brenda
Tye, C.E.; Lorenz, R.L.; Bartlett, J.D.
Lysosomal protease expression in mature enamel
Cells Tissues Organs
189
111-114
2009
Mus musculus
brenda
Bista, P.; Mele, D.A.; Baez, D.V.; Huber, B.T.
Lymphocyte quiescence factor Dpp2 is transcriptionally activated by KLF2 and TOB1
Mol. Immunol.
45
3618-3623
2008
Homo sapiens, Mus musculus
brenda
Rhnert, P.; Schmidt, W.; Emmerlich, P.; Goihl, A.; Wrenger, S.; Bank, U.; Nordhoff, K.; Tger, M.; Ansorge, S.; Reinhold, D.; Striggow, F.
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
J. Neuroinflammation
9
44
2012
Rattus norvegicus
brenda