Disease on EC 3.4.11.1 - leucyl aminopeptidase
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Abortion, Spontaneous
ERAP, KIR and HLA-C gene interaction in susceptibility to recurrent spontaneous abortion in the Polish population.
Abortion, Threatened
[Serum leucine aminopeptidase activity in threatened abortion, prolonged pregnancy and pregnancy toxemias]
Adenocarcinoma
Biochemical methods for predicting metastatic ability of prostatic cancer utilizing the dunning R-3327 rat prostatic adenocarcinoma system as a model.
Adenocarcinoma
Cytoenzymology of benign and malignant tumours of the corpus uteri. III. Alkaline phosphatase, non-specific esterase and leucine aminopeptidase.
Adenoma, Bile Duct
[Usefulness of carbohydrate antigen 19-9 (CA19-9) for the diagnosis of cholangioma. As a role of screening patients with the elevation of serum alkaline phosphatase, leucine aminopeptidase and/or gamma-glutamyl transpeptidase]
Appendicitis
Experimental model of acute appendicitis in the rabbit with determination of leucine amino peptidase (LAP) and acid phosphatase (acid-P) activities in portal blood samples.
Arthritis
[Determination of leucine aminopeptidase in the serum and synovial fluid of patients with progressive chronic polyarthritis]
Arthritis, Psoriatic
ERAP1 and ERAP2 Gene Variations Influence the Risk of Psoriatic Arthritis in Romanian Population.
Arthritis, Rheumatoid
Alkaline phosphatase isoenzyme activities in rheumatoid arthritis: hepatobiliary enzyme dissociation and relation to disease activity.
Arthritis, Rheumatoid
Evaluation of the renal injury from gold salts and nonsteroidal anti-inflammatory drugs in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Expression of ERAP2 and LST1 is increased before start of therapy in rheumatoid arthritis patients with good clinical response to glucocorticoids.
Asthma
[Leucine aminopeptidase activity (LAP) in the serum and urine of patients with allergic bronchial asthma]
Autoimmune Diseases
Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus.
Autoimmune Diseases
ERAP1 and HLA-C interaction in inflammatory bowel disease in the Spanish population.
Autoimmune Diseases
Influence of ERAP1 and ERAP2 gene polymorphisms on disease susceptibility in different populations.
Autoimmune Diseases
Peptide Trimming for MHC Class I Presentation by Endoplasmic Reticulum Aminopeptidases.
Autoimmune Diseases
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies.
Autoimmune Diseases
The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective.
Azotemia
Lactic dehydrogenase, leucine aminopeptidase, alpha globulin, and azotemia in circulatory stress.
Bacterial Infections
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing.
Bile Duct Neoplasms
[Diagnostic significance of serum leucine aminopeptidase, alkaline phosphatase and lactic dehydrogenase isozymes in liver and bile duct cancer]
Biliary Atresia
Serum leucine aminopeptidase activity in normal infants, in biliary atresia, and in other diseases.
Biliary Tract Diseases
[Comparative studies of the activity of leucine aminopeptidase and glycyl aminopeptidase in liver and biliary tract diseases]
Biliary Tract Diseases
[Comparative study of leucyl aminopeptidase and glycyl aminopeptidase activity in liver and biliary tract diseases. I. Behavior of both enzymes in serum and liver tissue]
Birdshot Chorioretinopathy
A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.
Birdshot Chorioretinopathy
The genetics, structure and function of the M1 aminopeptidase oxytocinase subfamily and their therapeutic potential in immune-mediated disease.
Birdshot Chorioretinopathy
The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective.
Blister
Hepatic toxicity in the rhesus monkey treated with chenodeoxycholic acid for 6 months: biochemical and ultrastructural studies.
Blister
[Leucine aminopeptidase activity in blood serum & blister content. II. Studies in patients with psoriasis, neurodermatitis diffusa, dermatitis, eczema & other dermatoses.]
Breast Neoplasms
A monoclonal antibody driven biodiagnostic system for the quantitative screening of breast cancer.
Breast Neoplasms
Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products.
Breast Neoplasms
Leucine aminopeptidase 3 promotes migration and invasion of breast cancer cells through upregulation of fascin and matrix metalloproteinases-2/9 expression.
Breast Neoplasms
Serum leucine aminopeptidase estimation: a sensitive prognostic indicator of invasiveness in breast carcinoma.
Breast Neoplasms
The combined action of two enzymes in human serum can mimic the activity of cathepsin B.
Breast Neoplasms
Vimentin plays an important role in the promotion of breast cancer cell migration and invasion by leucine aminopeptidase 3.
Carcinoma
Biological markers as an aid in the clinical management of patients with liver metastases.
Carcinoma
Changes in serum acid and alkaline phosphatase and leucine aminopeptidase activities following massage of the prostate. Value in differentiating carcinoma from benign hyperplasia of the prostate.
Carcinoma
Differences in the leucine aminopeptidase activity in extracts from human prostatic carcinoma and benign prostatic hyperplasia.
Carcinoma
Disaccharidases, leucine aminopeptidase, and glucose uptake in intestinalized gastric mucosa and in gastric carcinoma.
Carcinoma
ELEVATED SERUM LEUCINE AMINOPEPTIDASE ACTIVITY: CLINICAL SIGNIFICANCE IN PANCREATIC CARCINOMA.
Carcinoma
FACS quantitation of leucine aminopeptidase and acid phosphatase on tumor-associated macrophages from metastatic and nonmetastatic mouse mammary tumors.
Carcinoma
Histochemically demonstrable enzyme activities and their independence of the hormone receptor content in female breast carcinoma.
Carcinoma
Leucine amino peptidase a better indicator of carcinoma of liver, biliary tract and pancreas.
Carcinoma
Leucine aminopeptidase; its nonspecificity as a test for carcinoma of the pancreas.
Carcinoma
Overexpression of leucine aminopeptidase 3 contributes to malignant development of human esophageal squamous cell carcinoma.
Carcinoma
SERUM LACTIC DEHYDROGENASE, LEUCINE AMINOPEPTIDASE AND 5-NUCLEOTIDASE ACTIVITIES: OBSERVATION IN PATIENTS WITH CARCINOMA OF THE PANCREAS AND HEPATOBILIARY DISEASE.
Carcinoma
Serum leucine amino peptidase activity in carcinoma of the stomach with metastases.
Carcinoma
Serum leucine aminopeptidase activity: findings in carcinoma of the pancreas, pregnancy and other disorders.
Carcinoma
Special features of intestinal metaplasia and its relation to early gastric carcinoma in man: observation by a method in which leucine aminopeptidase activity is used.
Carcinoma
Study of activities of arginase, hexosaminidase, and leucine aminopeptidase in prostate fluid.
Carcinoma
The diagnostic value of determinations of serum leucine aminopeptidase concentrations in carcinoma of the pancreas.
Carcinoma
The serum leucine aminopeptidase test: an appraisal of its value in diagnosis of carcinoma of pancreas.
Carcinoma
[Alkaline phosphatase and leucine aminopeptidase in untreated carcinoma of the endometrium]
Carcinoma
[Diagnostic value of biochemical tumor markers in serum of patients with cancer of the ovary]
Carcinoma
[Histochemical observations on leucine aminopeptidase activity in cervical carcinoma.]
Carcinoma
[Markers of carcinoma of the ovary: serum cystine aminopeptidase and leucine aminopeptidase, reliable diagnostic parameters?]
Carcinoma, Ductal
Histochemically demonstrable enzyme activities and their independence of the hormone receptor content in female breast carcinoma.
Carcinoma, Hepatocellular
Enzyme histochemical study on hepatoma--the relation between enzyme activity and histological type.
Carcinoma, Hepatocellular
Estimation of leucine aminopeptidase and 5-nucleotidase increases alpha-fetoprotein sensitivity in human hepatocellular carcinoma cases.
Carcinoma, Hepatocellular
Expression of leucine aminopeptidase 3 (LAP3) correlates with prognosis and malignant development of human hepatocellular carcinoma (HCC).
Carcinoma, Hepatocellular
In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe.
Carcinoma, Hepatocellular
In vivo imaging via a red-emitting fluorescent probe to diagnosing liver cancer or drug-induced liver disease.
Carcinoma, Hepatocellular
Leucine amino peptidase a better indicator of carcinoma of liver, biliary tract and pancreas.
Carcinoma, Hepatocellular
Proteomic Analysis of Hepatocellular Carcinoma Tissues With Encapsulation Shows Up-regulation of Leucine Aminopeptidase 3 and Phosphoenolpyruvate Carboxykinase 2.
Carcinoma, Small Cell
Biological markers as an aid in the clinical management of patients with liver metastases.
Cardiovascular Diseases
RNA-sequencing analysis of differential gene expression associated with arterial stiffness.
Cataract
[Variation of some enzymatic activities of the rat crystalline lens in experimental galactose cataract (lactate dehydrogenase, leucine aminopeptidase, phosphoglucose isomerase]
Celiac Disease
[Morphologic and histochemical study of the intestinal mucosa in celiac disease. Leucine aminopeptidase behavior in gluten intolerance]
Chemical and Drug Induced Liver Injury
In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe.
Chickenpox
[Behavior of leucine aminopeptidase in the blood of individuals with measles, scarlet fever and chickenpox]
Cholestasis
Effect of sodium tauroursodeoxycholate on phalloidin-induced cholestasis in rats.
Cholestasis
Triton-polyacrylamide gel electrophoresis and leucine aminopeptidase activity staining detect Triton-slowed bands including high-molecular-mass aminopeptidase N (CD13) isoform in cholestatic patient sera.
Cholestasis
Value of serum alkaline phosphatase, aminotransferases, gamma-glutamyl transferase, leucine aminopeptidase, and bilirubin in the distinction between benign and malignant diseases causing jaundice and cholestasis: results from a prospective study.
Cholestasis
[Comparative study of lipoprotein-X and leucine aminopeptidase in the diagnosis of cholestasis]
Cholestasis
[Increased serum alkaline phosphatase induced by DT-5061, an oral contraceptive, in rats]
Cholestasis, Intrahepatic
[Changes in hepatobiliary enzymes and its isoenzymes in intrahepatic cholestasis in pregnancy]
Cholestasis, Intrahepatic
[Hypertension and bilateral stenosis of the renal artery associated with congenital hypoplasia of the intrahepatic bile ducts (author's transl)]
Choriocarcinoma
Cystine animopeptidase and leucine aminopeptidase of choriocarcinoma cells grown in culture.
Choriocarcinoma
The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma.
Clonorchiasis
Molecular identification and characterization of leucine aminopeptidase 2, an excretory-secretory product of Clonorchis sinensis.
Coccidiosis
[Alteration of enzyme activities in serum of Eimeria stiedai infected rabbits (author's transl)]
Communicable Diseases
Influence of ERAP1 and ERAP2 gene polymorphisms on disease susceptibility in different populations.
Communicable Diseases
Polymorphisms in ERAP1 and ERAP2 are shared by Caninae and segregate within and between random- and pure-breeds of dogs.
COVID-19
Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms.
Crohn Disease
Brief Report: Functional Interaction of Endoplasmic Reticulum Aminopeptidase 2 and HLA-B27 Activates the Unfolded Protein Response.
Crohn Disease
Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection.
Crohn Disease
Increased proteolysis and leucine aminopeptidase activity in faeces of patients with Crohn's disease.
Crohn Disease
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies.
Cystadenoma, Serous
[A comparison of the enzyme activities of alkaline and acid phosphatase, lactic acid dehydrogenase and leucine aminopeptidase from the wall and fluid of human ovarian follicles, cysts and serous cystadenomas (author's transl)]
Cystic Fibrosis
The experience with the foetal diagnosis of the cystic fibrosis in the second and first trimester.
Cysts
Essential Role for an M17 Leucine Aminopeptidase in Encystation of Acanthamoeba castellanii.
Cysts
[A comparison of the enzyme activities of alkaline and acid phosphatase, lactic acid dehydrogenase and leucine aminopeptidase from the wall and fluid of human ovarian follicles, cysts and serous cystadenomas (author's transl)]
Cytomegalovirus Infections
Serum leucine aminopeptidase for monitoring viral infections with plasmacytoid reaction.
Dental Calculus
[Leucine aminopeptidase and aminotransferase activity in human dental calculus, dental deposit and saliva]
Dental Deposits
[Leucine aminopeptidase and aminotransferase activity in human dental calculus, dental deposit and saliva]
Dermatitis
[Leucine aminopeptidase activity in blood serum & blister content. II. Studies in patients with psoriasis, neurodermatitis diffusa, dermatitis, eczema & other dermatoses.]
Diabetes Mellitus, Type 1
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies.
Digestive System Diseases
Electrophoretic patterns of serum leucine aminopeptidase in patients with pancreatic and hepatobiliary disease.
Digestive System Diseases
SERUM LACTIC DEHYDROGENASE, LEUCINE AMINOPEPTIDASE AND 5-NUCLEOTIDASE ACTIVITIES: OBSERVATION IN PATIENTS WITH CARCINOMA OF THE PANCREAS AND HEPATOBILIARY DISEASE.
Digestive System Diseases
Serum leucine aminopeptidase in pancreatic and hepatobiliary diseases.
Digestive System Diseases
Triton-polyacrylamide gel electrophoresis and leucine aminopeptidase activity staining detect Triton-slowed bands including high-molecular-mass aminopeptidase N (CD13) isoform in cholestatic patient sera.
Digestive System Diseases
[DIAGNOSTIC VALUE OF THE ENZYME LEUCINE AMINOPEPTIDASE. II. INVESTIGATION IN CHOLOSTATIC, HEPATOBILIARY DISEASES AND OTHER DIGESTIVE TRACT PROCESSES.]
Digestive System Diseases
[ELECTROPHORETIC FRACTIONATION OF "CELLOGEL" OF BLOOD LEUCINE AMINOPEPTIDASE IN HEPATOBILIARY DISEASES.]
Digestive System Diseases
[MECHANISM OF ABNORMAL SERUM LAP ISOZYME IN HEPATOBILIARY DISORDERS AS INDICATED BY URINARY LEUCINE AMINOPEPTIDASE (LAP) ZYMOGRAM.]
Digestive System Diseases
[SIGNIFICANCE OF SERUM LEUCINE AMINOPEPTIDASE ISOZYMES IN HEPATOBILIARY DISORDERS.]
Diphtheria
[Modification of beta-glucuronidase, leucine aminopeptidase and alkaline phosphatase activities by diphtheria toxin in experimental animals]
Duodenal Ulcer
Study of enzyme activities in the descending part of the duodenum in patients of duodenal ulcer.
Eclampsia
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Eczema
[Leucine aminopeptidase activity in blood serum & blister content. II. Studies in patients with psoriasis, neurodermatitis diffusa, dermatitis, eczema & other dermatoses.]
Elephantiasis, Filarial
Tissue localization of collagenase and leucine aminopeptidase in the bovine filarial parasite Setaria cervi.
Endometrial Neoplasms
Adipocyte-derived leucine aminopeptidase suppresses angiogenesis in human endometrial carcinoma via renin-angiotensin system.
Endometrial Neoplasms
Expression of adipocyte-derived leucine aminopeptidase in endometrial cancer. Association with tumor grade and CA-125.
Endometrial Neoplasms
Possible involvement of adipocyte-derived leucine aminopeptidase via angiotensin II in endometrial carcinoma.
Endometrial Neoplasms
Serum cystine aminopeptidase and leucine aminopeptidase activity in women with benign and malignant uterine and ovarian tumors.
Epstein-Barr Virus Infections
Serum leucine aminopeptidase for monitoring viral infections with plasmacytoid reaction.
Esophageal Squamous Cell Carcinoma
Overexpression of leucine aminopeptidase 3 contributes to malignant development of human esophageal squamous cell carcinoma.
Essential Hypertension
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.
Fascioliasis
Vaccination with cathepsin L proteinases and with leucine aminopeptidase induces high levels of protection against fascioliasis in sheep.
Fetal Death
Uteroplacental blood flow and uteroplacental shunt rates in normal and prolonged pregnancies in rats.
Fibrosarcoma
Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
A new glucose-6-phosphate dehydrogenase deficiency variant, G6PD Mizushima, showing increases in serum ferritin and cytosol leucine aminopeptidase levels.
Glucosephosphate Dehydrogenase Deficiency
A new glucose-6-phosphate dehydrogenase deficiency variant, G6PD Mizushima, showing increases in serum ferritin and cytosol leucine aminopeptidase levels.
Granuloma
Mononuclear phagocytes from carrageenan-induce granulomas. Isolation, cultivation, and characterization.
Granuloma
Streptozotocin diabetes: prolonged inflammatory response with delay in granuloma formation.
Granuloma
[Enzymehistochemical and immunopathological findings in the guinea pig lung after repeated doses of Freund's adjuvant (author's transl)]
Head and Neck Neoplasms
[ENZYMES IN CLINICAL PRACTICE: LEUCINE AMINOPEPTIDASE. ITS IMPORTANCE IN DIAGNOSIS OF BILIARY DISEASES AND IN CASES OF CANCER OF THE HEAD OF THE PANCREAS.]
HELLP Syndrome
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Hepatitis
[Changes in serum leucine aminopeptidase activity (expressed in U./G.R.) in children with contagious hepatitis]
Hepatitis
[Changes in the serum phosphohexose isomerase and leucine aminopeptidase levels during lysozyme treatment of viral hepatitis in childhood]
Hepatitis
[Effect of glucocorticoids (GCS) on the enzyme activity in viral hepatitis (VH). II. Isoenzymatic profile of leucine aminopeptidase (LAP) and glycyl aminopeptidase (GAP) of blood serum]
Hepatitis
[Effects of glucocorticoids on enzyme activity in viral hepatitis. I. Behavior of serum leucine aminopeptidase and glycine aminopeptidase]
Hepatitis
[Leucine aminopeptidase and cystinyl aminopeptidase activity of serum during the course of viral hepatitis, with reference to the effect of cortico therapy]
Hepatitis
[Leucine aminopeptidase in the differential diagnosis of viral hepatitis and mechanical jaundice]
Hepatitis
[Serum beta-glucuronidase and leucine aminopeptidase in the diagnosis of hepatitis and cirrhosis.]
Hepatitis
[Suitability of "classical" leucine aminopeptidase (LAP) as indicator enzyme in hepatitis epidemica acuta. Differentiation between leucine aminopeptidase and arylamidase in hepatobiliary illnesses]
Hepatitis
[The activity of leucine aminopeptidase in different clinical course types of hepatitis in childhood]
Hepatitis A
[Blood and urinary leucinaminopeptidase (LAP) levels in infectious hepatitis in childhood]
Hepatitis A
[Determination of serum leucine aminopeptidase by a new method in children with latent infectious hepatitis]
Hepatitis A
[On the serum L-leucine aminopeptidase activity in children with acute infectious hepatitis.]
Hepatitis, Chronic
[The significance of serum gamma-glutamyl transpeptidase determination in the differentiation of icterus of various etiologies]
Herpes Simplex
[Leucine aminopeptidase activity in a simulation of keratitis due to serotypes I and II of the herpes simplex virus]
Histiocytic Sarcoma
Prognostic evaluation of serum leucine aminopeptidase in malignancy of lymphoreticular and haemopoietic cell lines in children, with special reference to malignant histiocytosis of the intestine.
HIV Infections
Bestatin-mediated inhibition of leucine aminopeptidase may hinder HIV infection.
Hydatidiform Mole
Serum leucine aminopeptidase activity in normal pregnancy and in patients with hydatidiform mole.
Hypersensitivity
Enhancement of delayed-type hypersensitivity by bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase.
Hypersensitivity, Delayed
Increased sensitivity of IL2-dependent cultured T cells and enhancement of in vitro IL2 production by human lymphocytes treated with Bestatin.
Hypersensitivity, Delayed
New microbial secondary metabolites under preclinical development for cancer treatment.
Hypertension
Gene Variation of Endoplasmic Reticulum Aminopeptidases 1 and 2, and Risk of Blood Pressure Progression and Incident Hypertension among 17,255 Initially Healthy Women.
Hypertension
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Hypertension
Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension.
Hypertension, Portal
Activity of brush border membrane enzymes in proximal jejunum of portal hypertensive rats.
Hyperthyroidism
[Cytochemical properties of peripheral blood neutrophils in patients with hyperthyroidism]
Immune System Diseases
Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.
Infections
A Complex Array of Proteins Related to the Multimeric Leucine Aminopeptidase of Tomato.
Infections
A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?
Infections
Decreased activity of brush border membrane-bound digestive enzymes in small intestines from pigs experimentally infected with porcine epidemic diarrhea virus.
Infections
Does Convit vaccine (BCG + Mycobacterium leprae) afford protection against biochemical changes in renal brush border membrane in experimental leprosy?
Infections
Effects of size of Trichostrongylus colubriformis infections on histopathology of the mucosa along the whole small intestine in rabbits.
Infections
Endoplasmic reticulum aminopeptidase 2 (ERAP2) haplotypes play a role in modulating susceptibility to HIV infection.
Infections
Evaluation of recombinant SjLAP and SjFBPA in detecting antibodies to Schistosoma japonicum.
Infections
Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection.
Infections
Leucine aminopeptidase is an immunodominant antigen of Fasciola hepatica excretory and secretory products in human infections.
Infections
Localization and post-translational processing of the wound-induced leucine aminopeptidase proteins of tomato.
Infections
Pseudomonas aeruginosa Leucine Aminopeptidase Influences Early Biofilm Composition and Structure via Vesicle-Associated Antibiofilm Activity.
Infections
Renal brushborder membrane vesicle. Study of marker enzymes and uptake of nutrients in Mycobacterium leprae infected mice.
Infections
The induction of tomato leucine aminopeptidase genes (LapA) after Pseudomonas syringae pv. tomato infection is primarily a wound response triggered by coronatine.
Infections
The recombinant gut-associated M17 leucine aminopeptidase in combination with different adjuvants confers a high level of protection against Fasciola hepatica infection in sheep.
Infections
[Antibody responses to leucine aminopeptidase in Schistosoma japonicum infection].
Infections
[Serum activity of leucine aminopeptidase in lymphotropic infections and in malignant lymphomas]
Infections
[Significance of the study of leucine aminopeptidase activity of the blood serum in patients with suppurative surgical infections]
Infectious Mononucleosis
[Evaluation of leucine aminopeptidase activity (LAP) in infectious mononucleosis]
Influenza, Human
A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?
Intervertebral Disc Degeneration
Correlation Between Proteolytic Enzymes and Microangiogenesis in Degenerative Intervertebral Disc Nucleus.
Keratitis
[Leucine aminopeptidase activity in a simulation of keratitis due to serotypes I and II of the herpes simplex virus]
Leishmaniasis
Structural and Functional Basis of Potent Inhibition of Leishmanial Leucine Aminopeptidase by Peptidomimetics.
Leprosy, Lepromatous
Urinary excretion of renal brush-border enzymes in lepromatous leprosy--a preliminary investigation.
leucyl aminopeptidase deficiency
Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.
leucyl aminopeptidase deficiency
Brief Report: Functional Interaction of Endoplasmic Reticulum Aminopeptidase 2 and HLA-B27 Activates the Unfolded Protein Response.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
CHROMATOGRAPHIC STUDIES ON LEUCINE AMINOPEPTIDASE IN NORMAL HUMAN GRANULOCYTES AND IN CELLS OF ACUTE AND CHRONIC MYELOID LEUKEMIA.
Leukoplakia
[The effect of antioxidants on the activity of acid hydrolases in blood leukocytes from patients with leukoplakia of mouth mucosa]
Liver Cirrhosis
[Effect of hydrocortisone on the activity of plasma and hepatic tissue enzymes. I. Leucylaminopeptidase (LAP) and glycylaminopeptidase (GAP) activity in experimental liver cirrhosis and mechanical jaundice in rats]
Liver Cirrhosis, Experimental
[Effect of hydrocortisone on the activity of plasma and hepatic tissue enzymes. I. Leucylaminopeptidase (LAP) and glycylaminopeptidase (GAP) activity in experimental liver cirrhosis and mechanical jaundice in rats]
Liver Diseases
High serum levels of secretory IgA in liver disease: possible liver origin of the circulating secretory component.
Liver Diseases
Rational design of a fluorescent probe for the detection of LAP and its application in drug-induced liver injury.
Liver Diseases
Sephadex gel filtration of gamma-glutamyl-transpeptidase, alkaline phosphatase and leucine aminopeptidase in the serum of patients affected by various liver diseases.
Liver Diseases
[LEUCINAMINOPEPTIDASE ACTIVITY OF THE BLOOD OF PATIENTS WITH VARIOUS TYPES OF LIVER DISEASES.]
Liver Diseases
[Serum activity of leucine aminopeptidase in lymphotropic infections and in malignant lymphomas]
Liver Diseases, Alcoholic
Beta-hexosaminidase, leucine aminopeptidase, cystidyl aminopeptidase, hepatic enzymes and bilirubin in serum of chronic alcoholics with acute ethanol intoxication.
Liver Failure
Recommendation to Exclude Bile-Duct-Cannulated Rats with Hyperbilirubinemia for Proper Conduct of Biliary Drug Excretion Studies.
Liver Neoplasms
A ratiometric fluorescent probe based on quinoline for monitoring and imaging of Leucine aminopeptidase in liver tumor cells.
Liver Neoplasms
A Ratiometric Fluorescent Probe for Monitoring Leucine Aminopeptidase in Living Cells and Zebrafish Model.
Liver Neoplasms
In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe.
Lupus Erythematosus, Systemic
Serum leucine aminopeptidase as an activity indicator in systemic lupus erythematosus: a study of 46 consecutive cases.
Lupus Erythematosus, Systemic
[The value of urinary enzyme determinations in systemic lupus erythematosus (author's transl)]
Lymphadenitis
Increased activities of cytosol aminopeptidase and lactate dehydrogenase in serum originate from lymphocytes in necrotizing lymphadenitis.
Lymphadenitis
[Serum activity of leucine aminopeptidase in lymphotropic infections and in malignant lymphomas]
Lymphatic Diseases
[Marked dissociation of leucine aminopeptidase activities by the use of 2 different substrates--application of the methods to lymphatic diseases]
Lymphocytic Choriomeningitis
Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses.
Lymphoma
[Serum activity of leucine aminopeptidase in lymphotropic infections and in malignant lymphomas]
Malabsorption Syndromes
The activities of alanine aminopeptidase, leucine aminopeptidase, proline dipeptidase and prolyl dipeptidase in the mucosa of the small intestine. Investigations on normal children and patients with the malabsorption syndrome.
Malaria
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development.
Malaria
Enzymatic characteristics and preventive effect of leucine aminopeptidase against Echinococcus multilocularis.
Malaria
In silico screening of novel inhibitors of M17 Leucine Amino Peptidase (LAP) of Plasmodium vivax as therapeutic candidate.
Malaria
Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites. Target for the antimalarial activity of bestatin.
Malaria
The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: the importance of active site metal ions in the binding of substrates and inhibitors.
Malnutrition
Interaction of malnutrition and difluoromethylornithine-induced intestinal mucosal damage: degree of severity and subsequent recovery.
Measles
Increased cytosol aminopeptidase and lactate dehydrogenase in serum originating from lymphocytes in measles and rubella infection.
Measles
[Behavior of leucine aminopeptidase in the blood of individuals with measles, scarlet fever and chickenpox]
Meningitis
Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.
Methemoglobinemia
Leucine aminopeptidase activity in plasma of rats, after combined carboxy- and methemoglobinemia.
Multiple Sclerosis
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies.
Multiple Sclerosis
[Isolation and various properties of leucine aminopeptidase from biological fluids of patients with multiple sclerosis]
Multiple Sclerosis
[Possible role of hydrolytic enzymes in the pathogenesis of multiple sclerosis]
Multiple Sclerosis
[Prognostic significance of determining myelin leucine aminopeptidase activity in disseminated sclerosis]
Mumps
[Blood leucine aminopeptidase (LAP) in epidemic parotitis. Comparative evaluation with blood lipase and amylase in salivary and pancreatic localization of the parotitis virus]
Muscular Diseases
[Histochemical evidence of leucine aminopeptidase activity in human skeletal muscle in myopathies]
Musculoskeletal Diseases
Renal injury in patients with rheumatoid arthritis treated with gold.
Myocardial Infarction
Prognostic significance of serum leucine aminopeptidase in myocardial infarction with left ventricular failure.
Myocardial Infarction
[The value of glycine peptidase, leucine aminopeptidase and -glutamyl transpeptidase determinations in distant diagnosis of myocardial infarction]
Neoplasm Metastasis
Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products.
Neoplasm Metastasis
Leucine amino peptidase a better indicator of carcinoma of liver, biliary tract and pancreas.
Neoplasm Metastasis
Leucine aminopeptidase 3 promotes migration and invasion of breast cancer cells through upregulation of fascin and matrix metalloproteinases-2/9 expression.
Neoplasm Metastasis
Serum leucine amino peptidase activity in carcinoma of the stomach with metastases.
Neoplasm Metastasis
Serum leucine aminopeptidase profile in cancers of gastro-intestinal tract with special reference to hepatic metastasis.
Neoplasm Metastasis
Transport mechanisms of bestatin in rabbit intestinal brush-border membranes: role of H+/dipeptide cotransport system.
Neoplasms
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing.
Neoplasms
A near-infrared fluorescent probe for monitoring leucine aminopeptidase in living cells.
Neoplasms
A new method to evaluate the enzyme-suppressing activity of a leucine aminopeptidase 3 inhibitor.
Neoplasms
A ratiometric fluorescent probe based on quinoline for monitoring and imaging of Leucine aminopeptidase in liver tumor cells.
Neoplasms
A Ratiometric Fluorescent Probe for Monitoring Leucine Aminopeptidase in Living Cells and Zebrafish Model.
Neoplasms
A turn-on fluorescence probe based on aggregation-induced emission for leucine aminopeptidase in living cells and tumor tissue.
Neoplasms
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.
Neoplasms
Characterization of a monoclonal antibody defining a macrophage activation-specific cell surface antigen.
Neoplasms
Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes.
Neoplasms
Cytoenzymology of benign and malignant tumours of the corpus uteri. III. Alkaline phosphatase, non-specific esterase and leucine aminopeptidase.
Neoplasms
Detection of leucine aminopeptidase activity in serum using surface-enhanced Raman spectroscopy.
Neoplasms
Diagnosis of hepatocellular carcinoma in patients with liver cirrhosis using liver function assays.
Neoplasms
Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma.
Neoplasms
Effect of a rhodium complex on alterations of hepatic function in thioacetamide-induced hyperplastic noduligenesis in rats.
Neoplasms
Electrochemical substrate for active profiling of cellular surface leucine aminopeptidase activity and drug resistance in cancer cells.
Neoplasms
Endoplasmic reticulum aminopeptidase 2 involvement in metastasis of oral cavity squamous cell carcinoma discovered by proteome profiling of primary cancer cells.
Neoplasms
Endoplasmic Reticulum Aminopeptidase 2, a common immunological link to adverse pregnancy outcomes and cancer clearance?
Neoplasms
Enhanced cleavage of diaminopimelate-containing isopeptides by leucine aminopeptidase and matrix metalloproteinases in tumors: application to bioadhesive peptides.
Neoplasms
Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer.
Neoplasms
EpCAM associates with endoplasmic reticulum aminopeptidase 2 (ERAP2) in breast cancer cells.
Neoplasms
Expression of adipocyte-derived leucine aminopeptidase in endometrial cancer. Association with tumor grade and CA-125.
Neoplasms
Expression of Endoplasmic Reticulum Aminopeptidases in EBV-B Cell Lines from Healthy Donors and in Leukemia/Lymphoma, Carcinoma, and Melanoma Cell Lines.
Neoplasms
FACS quantitation of leucine aminopeptidase and acid phosphatase on tumor-associated macrophages from metastatic and nonmetastatic mouse mammary tumors.
Neoplasms
Highly sensitive fluorescence imaging of cancer with avidin-protease probe conjugate.
Neoplasms
In Silico Screening for Novel Leucine Aminopeptidase Inhibitors with 3,4-Dihydroisoquinoline Scaffold.
Neoplasms
Increased sensitivity of IL2-dependent cultured T cells and enhancement of in vitro IL2 production by human lymphocytes treated with Bestatin.
Neoplasms
Influence of ERAP1 and ERAP2 gene polymorphisms on disease susceptibility in different populations.
Neoplasms
Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products.
Neoplasms
Interaction between ERAP Alleles and HLA Class I Types Support a Role of Antigen Presentation in Hodgkin Lymphoma Development.
Neoplasms
Leucine amino peptidase a better indicator of carcinoma of liver, biliary tract and pancreas.
Neoplasms
Leucine amino peptidase levels in hepatic and certain gastro intestinal tract cancers.
Neoplasms
Leucine aminopeptidase 3 promotes migration and invasion of breast cancer cells through upregulation of fascin and matrix metalloproteinases-2/9 expression.
Neoplasms
Leucine aminopeptidase activity; observations in patients with cancer of the pancreas and other diseases.
Neoplasms
Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe.
Neoplasms
Macrophage activation in rat models of inflammation and arthritis: determination of markers of stages of activation.
Neoplasms
Molecular mechanism of inflammatory response in mouse liver caused by exposure to CeCl(3).
Neoplasms
Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing.
Neoplasms
Near-Infrared Fluorescent Probe with Remarkable Large Stokes Shift and Favorable Water Solubility for Real-Time Tracking Leucine Aminopeptidase in Living Cells and In Vivo.
Neoplasms
Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane.
Neoplasms
Peptide Trimming for MHC Class I Presentation by Endoplasmic Reticulum Aminopeptidases.
Neoplasms
Polymorphisms in ERAP1 and ERAP2 are shared by Caninae and segregate within and between random- and pure-breeds of dogs.
Neoplasms
Prediction of portal vein invasion by hepatocellular carcinoma: a correlations between portal vein tumor thrombus and biochemical tests.
Neoplasms
Prognostic evaluation of serum leucine aminopeptidase in malignancy of lymphoreticular and haemopoietic cell lines in children, with special reference to malignant histiocytosis of the intestine.
Neoplasms
Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis.
Neoplasms
Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.
Neoplasms
Serum cystine aminopeptidase and leucine aminopeptidase activity in women with benign and malignant uterine and ovarian tumors.
Neoplasms
Serum lactic dehydrogenase, leucine aminopeptidase and alkaline phosphatase in the diagnosis of cancer.
Neoplasms
Serum leucine aminopeptidase profile in cancers of gastro-intestinal tract with special reference to hepatic metastasis.
Neoplasms
The colorimetric determination of leucine aminopeptidase in urine and serum of normal subjects and patients with cancer and other diseases.
Neoplasms
The effect of dietary n-3 and n-6 fatty acids on tumor necrosis factor-alpha production and leucine aminopeptidase levels in rat peritoneal macrophages.
Neoplasms
The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective.
Neoplasms
Transport mechanisms of bestatin in rabbit intestinal brush-border membranes: role of H+/dipeptide cotransport system.
Neoplasms
Tumor-associated macrophages of mouse mammary tumors. II. Differential distribution of macrophages from metastatic and nonmetastatic tumors.
Neoplasms
[Behavior of leucine aminopeptidase activity in blood serum in patients with malignant tumors in the mouth and neck area.]
Neoplasms
[Biochemical evaluation of the leucine aminopeptidase content of malignant neoplasms of the female genital system]
Neoplasms
[Cytology and enzymocytochemistry of nodose hyperplasia and cancer of the prostate]
Neoplasms
[Diagnostic significance of serum leucine aminopeptidase, alkaline phosphatase and lactic dehydrogenase isozymes in liver and bile duct cancer]
Neoplasms
[Diagnostic value of biochemical tumor markers in serum of patients with cancer of the ovary]
Neoplasms
[DIAGNOSTIC VALUE OF THE ENZYME LEUCINE AMINOPEPTIDASE. 3. STUDY OF ITS ACTIVITY IN TUMORS AND OTHER NON-GASTROENTEROLOGIC DISEASES. ORIGIN OF SERUM L.A.P. ACTIVITY . FINAL CONSIDERATIONS.]
Neoplasms
[ENZYMES IN CLINICAL PRACTICE: LEUCINE AMINOPEPTIDASE. ITS IMPORTANCE IN DIAGNOSIS OF BILIARY DISEASES AND IN CASES OF CANCER OF THE HEAD OF THE PANCREAS.]
Neoplasms
[Enzymological study of prostatic cancer. I. Changes of serum lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase, prostatic acid phosphatase, glutamic pyruvic transaminase, glutamic oxalacetic transaminase activity and lactic dehydrogenase isoenzymes in prostatic cancer under anti-androgenic treatment, with special reference to prognosis]
Neoplasms
[Enzymological study of prostatic cancer. II. Serum lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase, prostatic acid phosphatase activity and lactic dehydrogenase isoenzymes in prostatic cancer, with special reference to relation with stage and histological malignancy]
Neoplasms
[Leucine aminopeptidase activity in some neoplasms of the female genital apparatus before and after irradiation]
Neoplasms
[Leucine aminopeptidase activity in the urine of patients with malignant tumors.]
Neoplasms
[Proceedings: Gamma-glutamyl transpeptidase, leucine aminopeptidase and alkaline phosphatase in the serum and urine in the diagnosis of neoplasms]
Neoplasms
[STUDIES ON THE CAUSE OF INCREASED LEUCINE AMINOPEPTIDASE ACTIVITY IN THE URINE DURING TUMOR IRRADIATION.]
Neoplasms
[The leucine aminopeptidase (LAP) in tumor cells and its significance in destructive tumor growth]
Neoplasms
[THE LEUCINE AMINOPEPTIDASE. ITS IMPORTANCE IN THE DIAGNOSIS OF BILIARY DISEASES AND IN CASES OF NEOPLASM OF THE HEAD OF THE PANCREAS.]
Neoplasms
[The significance of serum leucine aminopeptidase (P-LAP) determination in the gynecological malignancies]
Neoplasms
[Urological neoplasms and enzyme. IV. Studies on the alteration of lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, and total acid phosphatase activities and LDH isozymes in experimentally induced renal tumors with dimethylnitrosamine]
Neoplasms
[Urological neoplasms and enzymes. V. Studies on the alteration of lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase activities and LDH isozymes in experimentally induced renal tumors with lead acetate]
Nephrotic Syndrome
Activity of serum enzymes in puromycin aminonucleoside-induced nephrotic syndrome.
Nervous System Diseases
[Leucine aminopeptidase activity in the cerebrospinal fluid in nervous system diseases]
Nervous System Diseases
[Results of clinical and immunoenzymatic studies of neurospecific leucine aminopeptidase in patients with neurologic disorders]
Neurodermatitis
[Leucine aminopeptidase activity in blood serum & blister content. II. Studies in patients with psoriasis, neurodermatitis diffusa, dermatitis, eczema & other dermatoses.]
Obesity
Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.
Odontogenic Cysts
Enzyme histochemical studies on the formation of hyalin bodies in the epithelium of odontogenic cysts.
Odontogenic Cysts
Odontogenic keratocysts: a clinical and histological study with special reference to enzyme histochemistry.
Ovarian Neoplasms
Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9.
Pancreatic Diseases
[Clinical significance of serum leucine aminopeptidase activity in liver, bile duct, and pancreatic diseases.]
Pancreatic Diseases
[Clinical significance of serum leucine aminopeptidase in hepatobiliary and pancreatic diseases.]
Pancreatic Diseases
[The behavior of leucine aminopeptidase and other enzymes in the blood serum in liver, biliary and pancreatic diseases.]
Pancreatic Diseases
[The heterogenecity of leucine aminopeptidase. Studies on the organs and serum in liver, biliary tract and pancreatic diseases.]
Pancreatic Neoplasms
Leucine aminopeptidase activity; observations in patients with cancer of the pancreas and other diseases.
Parasitic Diseases
Enzymatic characteristics and preventive effect of leucine aminopeptidase against Echinococcus multilocularis.
Parotitis
[Blood leucine aminopeptidase (LAP) in epidemic parotitis. Comparative evaluation with blood lipase and amylase in salivary and pancreatic localization of the parotitis virus]
Persistent Infection
Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni.
Persistent Infection
The ERAP gene is associated with HCV chronic infection in a Chinese Han population.
Placental Insufficiency
[Proteolytic activity of fetoplacental complex in norm and pathology].
Plasmacytoma
[Serum activity of leucine aminopeptidase in lymphotropic infections and in malignant lymphomas]
Pleural Effusion
[Gamma-glutamyl transferase, leucine aminopeptidase and creatine kinase in the pleural fluid and serum of patients with pleural effusion of neoplastic and infectious origin]
Pleural Effusion
[On lactate dehydrogenase and leucine aminopeptidase of the serum, pleural effusions and ascites determined by electrophoresis]
Pre-Eclampsia
A Novel ERAP2 Haplotype Structure in a Chilean Population: Implications for ERAP2 Protein Expression and Preeclampsia Risk.
Pre-Eclampsia
Association of ERAP2 gene variants with risk of pre-eclampsia among Iranian women.
Pre-Eclampsia
Association Study of Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 and 2 Genes in Iranian Women with Preeclampsia.
Pre-Eclampsia
Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study.
Pre-Eclampsia
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Pre-Eclampsia
Leucine aminopeptidase activity in maternal, cord blood and placenta of normal pregnancy and in pre-eclampsia.
Pre-Eclampsia
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.
Pre-Eclampsia
[Serum leucine aminopeptidase activity in threatened abortion, prolonged pregnancy and pregnancy toxemias]
Pregnancy, High-Risk
[Clinical significance of serum AKP, HSAP, LAP and gamma-GT determination in high-risk pregnancy]
Pregnancy, Prolonged
[Activity of oxytocinase, leucine aminopeptidase and glutamyl-transferase in term pregnancy and prolonged pregnancy]
Pregnancy, Prolonged
[Serum leucine aminopeptidase activity in threatened abortion, prolonged pregnancy and pregnancy toxemias]
Prostatic Hyperplasia
Differences in the leucine aminopeptidase activity in extracts from human prostatic carcinoma and benign prostatic hyperplasia.
Prostatic Neoplasms
Biochemical methods for predicting metastatic ability of prostatic cancer utilizing the dunning R-3327 rat prostatic adenocarcinoma system as a model.
Prostatic Neoplasms
[Enzymological study of prostatic cancer. I. Changes of serum lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase, prostatic acid phosphatase, glutamic pyruvic transaminase, glutamic oxalacetic transaminase activity and lactic dehydrogenase isoenzymes in prostatic cancer under anti-androgenic treatment, with special reference to prognosis]
Prostatic Neoplasms
[Enzymological study of prostatic cancer. II. Serum lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase, prostatic acid phosphatase activity and lactic dehydrogenase isoenzymes in prostatic cancer, with special reference to relation with stage and histological malignancy]
Prostatic Neoplasms
[Enzymological study of prostatic cancer. V. Alterations in the serum acid and alkaline phosphatase and leucine aminopeptidase activities following massage of the prostate]
Proteinuria
Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats.
Psoriasis
Leucine aminopeptidase and naphthylamidases in human epidermis. II. Biochemical and histochemical data in psoriasis and basaliomas.
Psoriasis
The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset.
Psoriasis
The genetics, structure and function of the M1 aminopeptidase oxytocinase subfamily and their therapeutic potential in immune-mediated disease.
Psoriasis
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies.
Psoriasis
The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective.
Psoriasis
[Leucine aminopeptidase activity in blood serum & blister content. II. Studies in patients with psoriasis, neurodermatitis diffusa, dermatitis, eczema & other dermatoses.]
Rotavirus Infections
Effect of orally administered epidermal growth factor on intestinal recovery of neonatal pigs infected with rotavirus.
Rubella
Increased cytosol aminopeptidase and lactate dehydrogenase in serum originating from lymphocytes in measles and rubella infection.
Sarcoma
Cytoenzymology of benign and malignant tumours of the corpus uteri. III. Alkaline phosphatase, non-specific esterase and leucine aminopeptidase.
Scarlet Fever
[Behavior of leucine aminopeptidase in the blood of individuals with measles, scarlet fever and chickenpox]
Schistosomiasis
Evaluation of recombinant SjLAP and SjFBPA in detecting antibodies to Schistosoma japonicum.
Schistosomiasis japonica
Evaluation of recombinant SjLAP and SjFBPA in detecting antibodies to Schistosoma japonicum.
Schistosomiasis japonica
[Antibody responses to leucine aminopeptidase in Schistosoma japonicum infection].
Skin Diseases
[Leucine aminopeptidase activity in blood serum & blister content. II. Studies in patients with psoriasis, neurodermatitis diffusa, dermatitis, eczema & other dermatoses.]
Skin Diseases
[ON ELECTROPHORETIC LOCALIZATION OF LEUCINE AMINOPEPTIDASE IN THE SERUM IN DERMATOSES USING AGAR GEL.]
Skin Diseases, Vesiculobullous
Histochemical study of bullous dermatoses. II. Leucine aminopeptidase.
Spondylitis
Substantial Influence of ERAP2 on the HLA-B*40:02 Peptidome. Implications for HLA-B*27-negative Ankylosing Spondylitis.
Spondylitis, Ankylosing
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.
Spondylitis, Ankylosing
Association of the genetic variants in the endoplasmic reticulum aminopeptidase 2 gene with ankylosing spondylitis susceptibility.
Spondylitis, Ankylosing
ERAP1 and HLA-C interaction in inflammatory bowel disease in the Spanish population.
Spondylitis, Ankylosing
ERAP1-ERAP2 haplotypes are associated with ankylosing spondylitis in Polish patients.
Spondylitis, Ankylosing
ERAP2 functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers.
Spondylitis, Ankylosing
ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients.
Spondylitis, Ankylosing
Functional Interaction of the Ankylosing Spondylitis Associated Endoplasmic Reticulum Aminopeptidase 2 with the HLA-B*27 Peptidome in Human Cells.
Spondylitis, Ankylosing
Lack of Associations between Endoplasmic Reticulum Aminopeptidase 2 Gene Polymorphisms and Ankylosing Spondylitis: A Meta-analysis with Trial Sequential Analysis.
Spondylitis, Ankylosing
Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.
Spondylitis, Ankylosing
Substantial Influence of ERAP2 on the HLA-B*40:02 Peptidome. Implications for HLA-B*27-negative Ankylosing Spondylitis.
Spondylitis, Ankylosing
The genetics, structure and function of the M1 aminopeptidase oxytocinase subfamily and their therapeutic potential in immune-mediated disease.
Spondylitis, Ankylosing
The interaction between host genetics and the microbiome in the pathogenesis of spondyloarthropathies.
Spondylitis, Ankylosing
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies.
Spondylitis, Ankylosing
The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective.
Starvation
Age-related response of the small intestine to severe starvation and refeeding in rats.
Starvation
The changes in the biochemical compositions and enzymatic activities of rotifer (Brachionus plicatilis, Müller) and Artemia during the enrichment and starvation periods.
Stomach Neoplasms
The histochemical studies on leucine aminopeptidase activity of human gastric cancers.
Testicular Neoplasms
Serum leucine amino peptidase levels as a marker in testicular tumours.
Tetanus
[BEHAVIOR OF LEUCINE AMINOPEPTIDASE IN THE BLOOD OF INDIVIDUALS WITH TETANUS TREATED WITH TETANUS ANTISERUM.]
Toxemia
[Statistical analysis of urinary estriol (U-E3), serum leucine aminopeptidase (LAP) and heat stable alkaline phosphatase (HSAP) in toxemia]
Trypanosomiasis
[MALIC DEHYDROGENASE, LEUCINE AMINOPEPTIDASE AND SUCCINIC DEHYDROGENASE ACTIVITY IN THE BLOOD OF THE GUINEA PIG WITH EXPERIMENTAL TRYPANOSOMIASIS DUE TO TRYPANOSOMA CRUZI.]
Tuberculosis
Polymorphisms in ERAP1 and ERAP2 Genes Are Associated With Tuberculosis in the Han Chinese.
Tuberculosis
The Activity of a Hexameric M17 Metallo-Aminopeptidase Is Associated With Survival of Mycobacterium tuberculosis.
Tuberculosis, Pulmonary
Enzyme levels in bronchoalveolar lavage fluid and serum of active pulmonary tuberculosis patients.
Urinary Bladder Neoplasms
[Enzymological study of bladder tumor. I. Serum lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase, prostatic acid phosphatase, glutamic pyruvic transaminase, glutamic oxalacetic transaminase activities and LDH isoenzymes: the relations with stage and histological grade]
Urologic Diseases
[Studies on leucine aminopeptidase (LAP) in urological diseases. I. Changed in LAP activity in renal homotransplants]
Urologic Diseases
[Studies on leucine aminopeptidase (LAP) in urological diseases. II. Early diagnosis of rejection reactions]
Urologic Neoplasms
[Urological neoplasms and enzyme. IV. Studies on the alteration of lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, and total acid phosphatase activities and LDH isozymes in experimentally induced renal tumors with dimethylnitrosamine]
Urologic Neoplasms
[Urological neoplasms and enzymes. V. Studies on the alteration of lactic dehydrogenase, alkaline phosphatase, leucine aminopeptidase, total acid phosphatase activities and LDH isozymes in experimentally induced renal tumors with lead acetate]
Urticaria
[Serum and urinary leucine aminopeptidase (LAP) activity in patients with chronic allergic urticaria and in healthy subjects]
Uterine Cervical Neoplasms
Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.
Uterine Cervical Neoplasms
[Study on the behavior of leucine aminopeptidase in cancer of the uterine cervix]
Uterine Neoplasms
Significance of serum tumor markers in patients with carcinoma of the ovary.
Uveitis
Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis.
Uveitis
[On the leucine aminopeptidase activity of the aqueous humor in the course of experimental anaphylactic uveitis. (Experimental note)]
Virus Diseases
Endoplasmic reticulum aminopeptidase 2 (ERAP2) haplotypes play a role in modulating susceptibility to HIV infection.
Virus Diseases
Peptide Trimming for MHC Class I Presentation by Endoplasmic Reticulum Aminopeptidases.
Virus Diseases
Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.
Virus Diseases
Serum leucine aminopeptidase for monitoring viral infections with plasmacytoid reaction.
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