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Information on EC 3.2.1.163 - 1,6-alpha-D-mannosidase

for references in articles please use BRENDA:EC3.2.1.163
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IUBMB Comments
The enzyme is specific for (1->6)-linked mannobiose and has no activity towards any other linkages, or towards p-nitrophenyl-alpha-D-mannopyranoside or baker's yeast mannan. It is strongly inhibited by Mn2+ but does not require Ca2+ or any other metal cofactor for activity.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Hydrolysis of the (1->6)-linked alpha-D-mannose residues in alpha-D-Manp-(1->6)-D-Manp
Synonyms
alpha 1,6-mannosidase, alpha-1,6-linkage-specific mannosidase, alpha-1,6-mannosidase, alpha-1,6-specific mannosidase, core-specific alpha1,6-mannosidase, core-specific lysosomal alpha (1-6)-mannosidase, core-specific lysosomal alpha 1,6-mannosidase, CpGH125, Epman, GH125 exo-alpha-1,6-mannosidase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
Hydrolysis of the (1->6)-linked alpha-D-mannose residues in alpha-D-Manp-(1->6)-D-Manp
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