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Information on EC 3.2.1.106 - mannosyl-oligosaccharide glucosidase

for references in articles please use BRENDA:EC3.2.1.106
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IUBMB Comments
This enzyme catalyses the first step in the processing of the N-glycan tetradecasaccharide precursor Glc3Man9GlcNAc2, which takes place in the endoplasmic reticulum, by removing the distal alpha-1,2-linked glucose residue. This and subsequent processing steps are required before complex N-glycans can be synthesized.
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The enzyme appears in viruses and cellular organisms
Synonyms
(Glc3)-glucosidase, acid alpha-glucosidase, alpha-glucosidase I, CHO-GAA, CWH41, Cwh41p, GAA, GCSI, Glc I, Glc3 oligosaccharide glucosidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Glc3Man9GlcNAc2-[protein] + H2O = Glc2Man9GlcNAc2-[protein] + beta-D-glucopyranose
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