Reference on EC 3.1.3.75 - phosphoethanolamine/phosphocholine phosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Roberts, S.J.; Stewart, A.J.; Sadler, P.J.; Farquharson, C.
Human PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activities
Biochem. J.
382
59-65
2004
Homo sapiens
Houston, B.; Seawright, E.; Jefferies, D.; Hoogland, E.; Lester, D.; Whitehead, C.; Farquharson, C.
Identification and cloning of a novel phosphatase expressed at high levels in differentiating growth plate chondrocytes
Biochim. Biophys. Acta
1448
500-506
1999
Gallus gallus (O73884)
Houston, B.; Stewart, A.J.; Farquharson, C.
PHOSPHO1-a novel phosphatase specifically expressed at sites of mineralisation in bone and cartilage
Bone
34
629-637
2004
Homo sapiens, Gallus gallus (O73884)
Stewart, A.J.; Schmid, R.; Blindauer, C.A.; Paisey, S.J.; Farquharson, C.
Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily
Protein Eng.
16
889-895
2003
Homo sapiens (Q8TCT1), Homo sapiens
Roberts, S.J.; Stewart, A.J.; Schmid, R.; Blindauer, C.A.; Bond, S.R.; Sadler, P.J.; Farquharson, C.
Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2
Biochim. Biophys. Acta
1752
73-82
2005
Homo sapiens (Q8TCT1), Homo sapiens
Massimelli, M.J.; Beassoni, P.R.; Forrellad, M.A.; Barra, J.L.; Garrido, M.N.; Domenech, C.E.; Lisa, A.T.
Identification, cloning, and expression of Pseudomonas aeruginosa phosphorylcholine phosphatase gene
Curr. Microbiol.
50
251-256
2005
Pseudomonas aeruginosa
Stewart, A.J.; Roberts, S.J.; Seawright, E.; Davey, M.G.; Fleming, R.H.; Farquharson, C.
The presence of PHOSPHO1 in matrix vesicles and its developmental expression prior to skeletal mineralization
Bone
39
1000-1007
2006
Gallus gallus
Beassoni, P.R.; Otero, L.H.; Massimelli, M.J.; Lisa, A.T.; Domenech, C.E.
Critical active-site residues identified by site-directed mutagenesis in Pseudomonas aeruginosa phosphorylcholine phosphatase, a new member of the haloacid dehalogenases hydrolase superfamily
Curr. Microbiol.
53
534-539
2006
Pseudomonas aeruginosa
Roberts, S.; Narisawa, S.; Harmey, D.; Millan, J.L.; Farquharson, C.
Functional involvement of PHOSPHO1 in matrix vesicle-mediated skeletal mineralization
J. Bone Miner. Res.
22
617-627
2007
Gallus gallus, Homo sapiens, Mus musculus
Beassoni, P.R.; Otero, L.H.; Lisa, A.T.; Domenech, C.E.
Using a molecular model and kinetic experiments in the presence of divalent cations to study the active site and catalysis of Pseudomonas aeruginosa phosphorylcholine phosphatase
Biochim. Biophys. Acta
1784
2038-2044
2008
Pseudomonas aeruginosa
Roberts, S.J.; Owen, H.C.; Farquharson, C.
Identification of a novel splice variant of the haloacid dehalogenase: PHOSPHO1
Biochem. Biophys. Res. Commun.
371
872-876
2008
Homo sapiens
Otero, L.H.; Beassoni, P.R.; Lisa, A.T.; Domenech, C.E.
Transition from octahedral to tetrahedral geometry causes the activation or inhibition by Znf2+ of Pseudomonas aeruginosa phosphorylcholine phosphatase
Biometals
23
307-314
2010
Pseudomonas aeruginosa
MacRae, V.E.; Davey, M.G.; McTeir, L.; Narisawa, S.; Yadav, M.C.; Millan, J.L.; Farquharson, C.
Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick
Bone
46
1146-1155
2010
Gallus gallus (O73884)
Beassoni, P.R.; Berti, F.P.; Otero, L.H.; Risso, V.A.; Ferreyra, R.G.; Lisa, A.T.; Domenech, C.E.; Ermacora, M.R.
Preparation and biophysical characterization of recombinant Pseudomonas aeruginosa phosphorylcholine phosphatase
Protein Expr. Purif.
71
153-159
2010
Pseudomonas aeruginosa (Q9HTR2), Pseudomonas aeruginosa
Otero, L.H.; Beassoni, P.R.; Domenech, C.E.; Lisa, A.T.; Albert, A.
Crystallization and preliminary X-ray diffraction analysis of Pseudomonas aeruginosa phosphorylcholine phosphatase
Acta Crystallogr. Sect. F
66
957-960
2010
Pseudomonas aeruginosa (Q9HTR2), Pseudomonas aeruginosa
Beassoni, P.R.; Otero, L.H.; Boetsch, C.; Domenech, C.E.; Gonzalez-Nilo, F.D.; Lisa, A.T.
Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa phosphorylcholine phosphatase
Biochim. Biophys. Acta
1814
858-863
2011
Pseudomonas aeruginosa (Q9HTR2), Pseudomonas aeruginosa
May, A.; Spinka, M.; Koeck, M.
Arabidopsis thaliana PECP1 - Enzymatic characterization and structural organization of the first plant phosphoethanolamine/phosphocholine phosphatase
Biochim. Biophys. Acta
1824
319-325
2012
Arabidopsis thaliana (Q9FZ62), Arabidopsis thaliana
Huesa, C.; Yadav, M.; Finnilae, M.; Goodyear, S.; Robins, S.; Tanner, K.; Aspden, R.; Millan, J.; Farquharson, C.
PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures
Bone
48
1066-1074
2011
Mus musculus (Q8R2H9)
Domenech, C.E.; Otero, L.H.; Beassoni, P.R.; Lisa, A.T.
Phosphorylcholine phosphatase: A peculiar enzyme of Pseudomonas aeruginosa
Enzyme Res.
2011
561841
2011
Pseudomonas aeruginosa (Q9HTR2), Pseudomonas aeruginosa
Otero, L.H.; Beassoni, P.R.; Boetsch, C.; Lisa, A.T.; Domenech, C.E.
Different effects of Mg2+ and Zn2+ on the two sites for alkylammonium compounds in Pseudomonas aeruginosa phosphorylcholine phosphatase
Enzyme Res.
2011
918283
2011
Pseudomonas aeruginosa (Q9HTR2), Pseudomonas aeruginosa
Yadav, M.; Simao, A.; Narisawa, S.; Huesa, C.; McKee, M.; Farquharson, C.; Millan, J.
Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: A unified model of the mechanisms of initiation of skeletal calcification
J. Bone Miner. Res.
26
286-297
2011
Mus musculus (Q8R2H9), Mus musculus C57BL/6 (Q8R2H9)
Bravo, Y.; Teriete, P.; Dhanya, R.P.; Dahl, R.; Lee, P.S.; Kiffer-Moreira, T.; Ganji, S.R.; Sergienko, E.; Smith, L.H.; Farquharson, C.; Millan, J.L.; Cosford, N.D.
Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1
Bioorg. Med. Chem. Lett.
24
4308-4311
2014
Homo sapiens
Huesa, C.; Houston, D.; Kiffer-Moreira, T.; Yadav, M.M.; Millan, J.L.; Farquharson, C.
The functional co-operativity of tissue-nonspecific alkaline phosphatase (TNAP) and PHOSPHO1 during initiation of skeletal mineralization
Biochem. Biophys. Rep.
4
196-201
2015
Mus musculus (Q8R2H9)
Huang, N.J.; Lin, Y.C.; Lin, C.Y.; Pishesha, N.; Lewis, C.A.; Freinkman, E.; Farquharson, C.; Millan, J.L.; Lodish, H.
Enhanced phosphocholine metabolism is essential for terminal erythropoiesis
Blood
131
2955-2966
2018
Homo sapiens (Q8TCT1), Homo sapiens, Mus musculus (Q8R2H9), Mus musculus
Morcos, M.W.; Al-Jallad, H.; Li, J.; Farquharson, C.; Millan, J.L.; Hamdy, R.C.; Murshed, M.
PHOSPHO1 is essential for normal bone fracture healing an animal study
Bone Joint Res.
7
397-405
2018
Mus musculus (Q8R2H9)
Pandya, M.; Rosene, L.; Farquharson, C.; Millan, J.; Diekwisch, T.
Intravesicular phosphatase PHOSPHO1 function in enamel mineralization and prism formation
Front. Physiol.
8
805
2017
Mus musculus (Q8R2H9)
Zweifler, L.E.; Ao, M.; Yadav, M.; Kuss, P.; Narisawa, S.; Kolli, T.N.; Wimer, H.F.; Farquharson, C.; Somerman, M.J.; Millan, J.L.; Foster, B.L.
Role of PHOSPHO1 in periodontal development and function
J. Dent. Res.
95
742-751
2016
Mus musculus (Q8R2H9)
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