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Information on EC 3.1.3.66 - phosphatidylinositol-3,4-bisphosphate 4-phosphatase

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EC Tree
IUBMB Comments
Mg2+-independent. This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyses Ins(1,3,4)P3 to Ins(1,3)P2. It also converts Ins(3,4)P2 into Ins-3-P.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
4-ptase-1, D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase, inositol polyphosphate 4 phosphatase A, inositol polyphosphate 4-phosphatase, inositol polyphosphate 4-phosphatase 1, inositol polyphosphate 4-phosphatase II, inositol polyphosphate 4-phosphatase type I, inositol polyphosphate 4-phosphatase type II, inositol polyphosphate 4-phosphatase-1, inositol-3,4-bisphosphate 4-phosphatase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate
show the reaction diagram
Mg2+-independent, the enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyses Ins(1,3,4)P3 to Ins(1,3)P2, it also converts Ins(3,4)P2 to Ins-3-P
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PATHWAY SOURCE
PATHWAYS
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