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Disease on EC 3.1.27.5 - pancreatic ribonuclease

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Threatened
[Circulating immune complexes and ribonuclease and 5'-nucleotidase activity in the blood of women with threatened abortion treated with acupuncture-reflexotherapy]
Acquired Immunodeficiency Syndrome
[Developments in the serological diagnosis of malignant diseases]
Acute Kidney Injury
The Role of Ribonuclease 1 and Ribonuclease Inhibitor 1 in Acute Kidney Injury after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair.
Acute Lung Injury
MCP-induced protein 1 attenuates sepsis-induced acute lung injury by modulating macrophage polarization via the JNK/c-Myc pathway.
Adenocarcinoma
Acetaminophen-induced proliferation of estrogen-responsive breast cancer cells is associated with increases in c-myc RNA expression and NF-kappaB activity.
Chemokine expression is associated with the accumulation of tumour associated macrophages (TAMs) and progression in human colorectal cancer.
Expression of COX-2 and PGE synthase and synthesis of PGE(2)in endometrial adenocarcinoma: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors.
Human pancreatic ribonuclease 1: expression and distribution in pancreatic adenocarcinoma.
Inhibition of telomerase by site-specific ribonucleases in gastric and esophageal adenocarcinoma.
Northern blot and ribonuclease protection study of alpha 2-adrenoceptor subtypes in cultured cell lines.
Production and characterisation of a recombinant single-chain anti ErbB2-clavin immunotoxin.
Ribonucleases expressed by human pancreatic adenocarcinoma cell lines.
Rutamarin, an Active Constituent from Ruta angustifolia Pers., Induced Apoptotic Cell Death in the HT29 Colon Adenocarcinoma Cell Line.
[Bacillus pumilus Ribonuclease Inhibits Migration of Human Duodenum Adenocarcinoma HuTu 80 Cells].
Adenocarcinoma, Bronchiolo-Alveolar
Internalization of Bacillus intermedius ribonuclease (BINASE) induces human alveolar adenocarcinoma cell death.
Adenoma
The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression.
Adenomatous Polyposis Coli
Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors.
Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.
Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma.
Adenosarcoma
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Aggressive Periodontitis
[Experience in the treatment of periodontosis with amorphous ribonuclease]
[Role of salivary ribonuclease in pathogenesis of periodontosis]
Albuminuria
Further evidence for tubular dysfunction in insulin dependent diabetes.
Alzheimer Disease
Altered phosphofructokinase mRNA levels but unchanged isoenzyme pattern in brains from patients with Alzheimer's disease.
Brain messenger RNA levels and ribonuclease activity in Alzheimer's disease.
Ribonuclease activities and distribution in Alzheimer's and control brains.
Role of ribonuclease and ribonuclease inhibitor activities in Alzheimer's disease.
Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.
[DNA diagnosis and laboratory tests]
Amyotrophic Lateral Sclerosis
5'ValCAC tRNA fragment generated as part of a protective angiogenin response provides prognostic value in amyotrophic lateral sclerosis.
A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective Activity.
A molecular dynamics based investigation reveals the role of rare Ribonuclease 4 variants in amyotrophic lateral sclerosis susceptibility.
Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis.
Insights into the role of ribonuclease 4 polymorphisms in amyotrophic lateral sclerosis.
Rare Angiogenin and Ribonuclease 4 variants associated with amyotrophic lateral sclerosis exhibit loss-of-function: a comprehensive in silico study.
Anaphylaxis
Delineation of the antigenic sites of oxidized ribonuclease in the mouse by passive cutaneous anaphylaxis and hemagglutination inhibition.
Anemia
Feedback modulation of renal and hepatic erythropoietin mRNA in response to graded anemia and hypoxia.
Ribonuclease inhibition of erythropoiesis in anemia of uremia.
Aortic Aneurysm, Thoracic
The Role of Ribonuclease 1 and Ribonuclease Inhibitor 1 in Acute Kidney Injury after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair.
Aortic Valve Stenosis
Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors.
Arthritis
[Serum ribonuclease in rheumatic disease. I. Serum alkaline ribonuclease activities in rheumatic diseases, especially in malignant rheumatoid arthritis]
Arthritis, Rheumatoid
[Serum ribonuclease in rheumatic disease. I. Serum alkaline ribonuclease activities in rheumatic diseases, especially in malignant rheumatoid arthritis]
Aspergillosis
Expression and characterization of Asp fI, an immunodominant allergen/antigen of A. fumigatus in insect cell.
Asthenozoospermia
Enhanced seminal plasma ribonuclease activities in azoospermia, severe oligiozoospermia, and asthenozoospermia.
RNASET2 is required for ROS propagation during oxidative stress-mediated cell death.
Asthma
Expression of beta 2-adrenergic receptor mRNA in peripheral lung in asthma and chronic obstructive pulmonary disease.
Astrocytoma
Children's brain tumour cells produce RNA particles with incomplete retrovirus characteristics.
Azoospermia
Enhanced seminal plasma ribonuclease activities in azoospermia, severe oligiozoospermia, and asthenozoospermia.
Bacteriuria
Urine concentrations of human beta-defensins and ribonuclease 7 in urinary tract infection and asymptomatic bacteriuria.
Blister
Physiological characterization of an Escherichia coli mutant altered in the structure of murein lipoprotein.
Brain Edema
[Activity of lysosomal enzymes in rabbit brain during the development of edema]
Brain Injuries
Expression of the activin axis and neuronal rescue effects of recombinant activin A following hypoxic-ischemic brain injury in the infant rat.
Breast Neoplasms
A metastatic breast tumor cell line, GI-101A, is estrogen receptor positive and responsive to estrogen but resistant to tamoxifen.
A Novel Ribonuclease from Rana Chensinensis and Its Potential for the Treatment of Human Breast Cancer.
A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells.
Acetaminophen-induced proliferation of estrogen-responsive breast cancer cells is associated with increases in c-myc RNA expression and NF-kappaB activity.
Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer.
An exon 5 deletion variant of the estrogen receptor frequently coexpressed with wild-type estrogen receptor in human breast cancer.
Coexpression of wild-type and variant oestrogen receptor mRNAs in a panel of human breast cancer cell lines.
Correlation of insulin-like growth factor-binding protein-3 messenger RNA with protein expression in primary breast cancer tissues: detection of higher levels in tumors with poor prognostic features.
Differential expression of an estrogen receptor messenger RNA containing exon 1' sequences in MCF-7 breast cancer cell line stocks.
Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue.
Expression and hormonal regulation of the Sox4 gene in mouse female reproductive tissues.
Expression of insulin-like growth factor binding proteins in human breast cancer correlates with estrogen receptor status.
Homeopathic medicines do not alter growth and gene expression in prostate and breast cancer cells in vitro.
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation.
Immunodetection of nmt55/p54nrb isoforms in human breast cancer.
Induction of 2'-5' oligoadenylate synthetase and activation of ribonuclease in tamoxifen treated human breast cancer cell lines.
Insulin-like growth factor II mRNA expression in human breast cancer.
Modulation of vitamin D receptor and estrogen receptor by 1,25(OH)2-vitamin D3 in T-47D human breast cancer cells.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
RNase MC2: a new Momordica charantia ribonuclease that induces apoptosis in breast cancer cells associated with activation of MAPKs and induction of caspase pathways.
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer.
The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium.
Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2.
[Analysis of gene expression of ribonuclease inhibitor in human breast cancer tissue]
[Effects of ribonuclease inhibitor on apoptosis and invasion of human breast cancer MDA-MB-231 cells].
[Lactoferrin--its role in defense against infection and immunotropic properties]
[Value of plasma ribonuclease as a marker for gynecologic tumors and breast tumors]
Brief, Resolved, Unexplained Event
Fetal hemoglobin synthesis determined by gamma-mRNA/gamma-mRNA + beta-mRNA quantitation in infants at risk for sudden infant death syndrome being monitored at home for apnea.
Bronchial Diseases
[The use of ribonuclease in the complex therapy of chronic bronchial diseases]
Carcinogenesis
Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase.
Development of experimental cancer in the head of the pancreas by surgical induction of tissue injury.
Discordant transforming growth factor beta 1 RNA and protein localization during chemical carcinogenesis of the skin.
Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration.
Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1.
SERUM RIBONUCLEASE DURING THE PROCESS OF DAB CARCINOGENESIS AND TUMOR GROWTH.
The distribution of ribonuclease activity in rat liver during azo-dye carcinogenesis.
Transgenic mice carrying a murine amylase 2.2/SV40 T antigen fusion gene develop pancreatic acinar cell and stomach carcinomas.
Tumor and metastasis suppression by the human RNASET2 gene.
Carcinoid Tumor
New insights into hypoxia-related mechanisms involved in different microvascular patterns of bronchopulmonary carcinoids and poorly differentiated neuroendocrine carcinomas. Role of ribonuclease T2 (RNASET2) and HIF-1?.
Carcinoma
A Cell-Autonomous Oncosuppressive Role of Human RNASET2 Affecting ECM-Mediated Oncogenic Signaling.
Action of deoxyribonuclease and ribonuclease on the growth of Ehrlich ascites carcinoma in mice.
An assessment of the clinical usefulness of plasma ribonuclease assays.
Carcinoma of the lung and cigarette smoking. Effect on serum ribonuclease activity.
Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase.
Cloning, genetic mapping and expression studies of the rat Brca1 gene.
Determination of ribonuclease activity in the serum of ovarian carcinoma patients.
Development of a hammerhead ribozyme against BCL-2. II. Ribozyme treatment sensitizes hormone-resistant prostate cancer cells to apoptotic agents.
Differential tissue-specific protein markers of vaginal carcinoma.
Effects of diethylstilbestrol diphosphate on serum and tissue ribonuclease levels in prostatic carcinoma.
Expression of the neurotensin gene in fetal human liver and fibrolamellar carcinoma.
Gastrointestinal tumor markers, other than carcinoembryonic antigen, and alpha fetal protein.
High expression of Wnt7b in human superficial bladder cancer vs invasive bladder cancer.
Highly efficient destruction of squamous carcinoma cells of the head and neck by photochemical internalization of Ranpirnase.
Human pancreatic ribonuclease 1: expression and distribution in pancreatic adenocarcinoma.
Increasing human serum ribonuclease activity is a concomitant phenomenon of ovarian carcinoma.
Invitro synergism between a novel amphibian oocytic ribonuclease (onconase(r)) and tamoxifen, lovastatin and Cisplatin, in human ovcar-3 ovarian-carcinoma cell-line.
Ovarian carcinoma: increase in clinical validity by simultaneous determination of SRA and CA 125.
Poly (C) avid ribonuclease estimation in patients with solid tumors. A critical evaluation.
Properties of a purified nucleolar ribonuclease from Ehrlich ascites carcinoma cells.
Ribonuclease as a tumour marker for pancreatic carcinoma.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Serum ribonuclease in patients with lung carcinoma.
Serum ribonuclease in the diagnosis of pancreatic carcinoma and in monitoring chemotherapy.
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines.
The poly(A)-containing ribonucleoproteins in the nucleus and the cytoplasm of ehrlich ascites carcinoma cells.
The ribonuclease activity of the cells of the mouse ascites carcinoma of Ehrlich.
Time-dependent changes of plasma ribonuclease activity in female Wistar rats under combination therapy of ovarian carcinoma.
[Action of ribonuclease and desoxyribonuclease on the incorporation of L-glutamic acid U-C-14 and methionine S-35 in tumor cells of Ehrlich's ascites carcinoma]
[Alterations of the plasma ribonuclease activity in female wistar rats under the conditions of combined therapy of the ovary carcinoma (author's transl)]
[Autoradiographic analysis of the effects of actinomycin D and ribonuclease on DNA synthesis in Ehrlich ascites carcinoma cells]
[CONTRIBUTIONS TO THE STUDY OF THE CYTOMORPHOLOGICAL CHANGES IN EHRLICH'S ASCITES CARCINOMA UNDER THE INFLUENCE OF RIBONUCLEASE AND DESOXYRIBONUCLEASE.]
[Diagnostic values of serum ribonuclease activities in pancreatic carcinoma (author's transl)]
[In vitro effects of ribonuclease on cells of bone marrow & Landschütz ascites carcinoma.]
[Serum ribonuclease activity in gynecologic neoplasms. The behavior of serum ribonuclease in ovarian cancer under cytostatic therapy]
[Serum ribonuclease activity in patients with gynaecologic malignomas (author's transl)]
[Serum ribonuclease and its importance for renal diagnosis (author's transl)]
[The effect of actinomycin-D and ribonuclease on the synthesis and content of DNA in the cells of Ehrlich's ascites carcinoma (microspectrophotometric and autoradiographic analysis)]
[The effects of ribonuclease on cells of Ehrlich carcinoma.]
[The value of poly-C-specific serum ribonuclease and CEA in the diagnosis of pancreatic carcinoma (author's transl)]
Carcinoma, Bronchogenic
Diagnostic value of serum ribonuclease (at pH-5) in bronchogenic carcinoma.
[The diagnostic value of ribonuclease in bronchoalveolar lavage fluid to bronchogenic carcinoma]
Carcinoma, Ehrlich Tumor
A ribonuclease specific for double-stranded RNA and two distinct ribonuclease H activities from the ribosomal salt wash fraction of Ehrlich ascites tumor cells.
DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. 3. Ribonuclease H and elongating activity of stimulatory factor S-II.
Inhibition of protein synthesis in a polyribosome-dependent cell-free system by a specific ribonuclease prepared from the follicles of two different stages of development of the silkmothAntherea pernyi.
Purification and properties of a novel nucleolar exoribonuclease capable of degrading both single-stranded and double-stranded RNA.
Ribonuclease activity in the Ehrlich ascites tumour.
Carcinoma, Embryonal
A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product.
RC-6 ribonuclease induces caspase activation, cellular senescence and neuron-like morphology in NT2 embryonal carcinoma cells.
Studies of dual promoters of mouse kappa-opioid receptor gene.
Carcinoma, Hepatocellular
A T1 ribonuclease fragment present in 18 S ribosomal RNA of Novikoff rat ascites hepatoma cells and absent from 18 S ribosomal RNA of HeLa cells.
Abrogation of the p16-Rb pathway in Korean hepatocellular carcinomas.
Cloning of the rat insulin-like growth factor binding protein-1 gene and analysis of its 5' promoter region.
Comparison of nucleotide sequences of large T1 ribonuclease fragments of 18S ribosomal RNA of rat and chicken.
Effects of cross-linked dimers of ribonuclease A or of lysozyme on the processing of endocytosed peroxidase by hepatoma cells.
Estimation of poly (C) avid serum ribonuclease in hepatoma patients.
Evidence for an ATP-dependent bile acid transport protein other than the canalicular liver ecto-ATPase in rats.
Induction of differentiation rescues HL-60 cells from Rana catesbeiana ribonuclease-induced cell death.
Inhibition of hepatitis B virus replication by ligand-mediated activation of RNase L.
Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene.
Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs.
Long Noncoding RNA RMRP Suppresses the Tumorigenesis of Hepatocellular Carcinoma Through Targeting microRNA-766.
Phosphodiesterase and ribonuclease activities of plasma membrane of rat liver and hepatoma.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells.
Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma.
RIBONUCLEASE ACTIVITY IN SOME TRANSPLANTABLE RAT HEPATOMAS.
Rutamarin, an Active Constituent from Ruta angustifolia Pers., Induced Apoptotic Cell Death in the HT29 Colon Adenocarcinoma Cell Line.
Structural analysis of nucleolar precursors of ribosomal ribonucleic acids. Sequence analysis of long oligonucleotides produced by T 1 ribonuclease digestion of nucleolar and ribosomal 28 S ribonucleic acid of Novikoff hepatoma ascites cells.
Studies on the function of intracellular ribonucleases. V. Ribonuclease activity in ribosomes and polysomes prepared from rat liver and hepatomas.
Synergistic cytotoxicity of Rana catesbeiana ribonuclease and IFN-gamma on hepatoma cells.
The distribution of acid and alkaline ribonuclease activities in preneoplastic and neoplastic rat livers.
[On the effects of ribonuclease on the membrane-bound ribosomes of liver and hepatoma tissue]
[Ribonuclease of histones in liver and hepatoma]
Carcinoma, Neuroendocrine
New insights into hypoxia-related mechanisms involved in different microvascular patterns of bronchopulmonary carcinoids and poorly differentiated neuroendocrine carcinomas. Role of ribonuclease T2 (RNASET2) and HIF-1?.
Carcinoma, Squamous Cell
Highly efficient destruction of squamous carcinoma cells of the head and neck by photochemical internalization of Ranpirnase.
Cardiomegaly
Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice.
Cardiomyopathies
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis.
Selective activation of N-acyl-D-glucosamine 2-epimerase expression in failing human heart ventricular myocytes.
Cardiomyopathy, Hypertrophic
Sudden death due to troponin T mutations.
Cardiomyopathy, Hypertrophic, Familial
An evaluation of ribonuclease protection assays for the detection of beta-cardiac myosin heavy chain gene mutations.
Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy.
Cataract
Ribonuclease activity and polysome profile in human senile cataract.
Cholangiocarcinoma
Thalidomide attenuates tumor growth and preserves fast-twitch skeletal muscle fibers in cholangiocarcinoma rats.
Cholera
Prediction of sequential antigenic regions in proteins.
[Biochemical and immunochemical characteristics of a new oral, chemical cholera bivalent vaccine and results of a trial of the preparation on volunteers]
Choriocarcinoma
Expression of the germ cell alkaline phosphatase gene in human choriocarcinoma cells.
Homeobox gene HB24, a regulator of haematopoiesis, is a candidate for regulating differentiation of the extra-embryonic trophoblast cell lineage.
Classical Swine Fever
Glycoprotein E2 of classical swine fever virus: expression in insect cells and identification as a ribonuclease.
High-resolution epitope mapping for monoclonal antibodies to the structural protein Erns of classical swine fever virus using peptide array and random peptide phage display approaches.
Colitis
Increased expression of epidermal growth factor-receptor in an experimental model of colitis in rats.
Increased expression of transforming growth factor alpha precursors in acute experimental colitis in rats.
Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.
Colitis, Ulcerative
[Study on ribonuclease activity in tissues of human colonorectal mucosa using synthetic substrate--activity in normal mucosa, cancer tissue and inflammatory mucosa of ulcerative colitis]
Colonic Neoplasms
Fetal and neoplastic expression of the neurotensin gene in the human colon.
Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity.
Rutamarin, an Active Constituent from Ruta angustifolia Pers., Induced Apoptotic Cell Death in the HT29 Colon Adenocarcinoma Cell Line.
Colorectal Neoplasms
A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells.
Comparative study of proteome between primary cancer and hepatic metastatic tumor in colorectal cancer.
Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish.
Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway.
Overexpression of ribonuclease inhibitor induces autophagy in human colorectal cancer cells via the Akt/mTOR/ULK1 pathway.
The ratio of splicing variants of MGC-24/CD164, a sialomucin, correlates with the metastatic potential of colorectal carcinomas.
[Proteome study of colorectal cancer genesis and hepatic metastasis]
Corneal Opacity
Pseudomonas aeruginosa-induced inflammation in the rat extended-wear contact lens model.
Cystic Fibrosis
Cystic fibrosis-like changes in saliva of healthy persons subjected to anaerobic exercise.
Cystic fibrosis. Carbohydrate metabolism in CF and in animal models for CF.
Identification and functional analysis of a bacteriocin, pyocin S6, with ribonuclease activity from a Pseudomonas aeruginosa cystic fibrosis clinical isolate.
Isozymes of ribonuclease in human serum and urine. II. A survey of patients with cystic fibrosis.
Proinflammatory cytokines inhibit secretion in rat bile duct epithelium.
Properties of purified salivary ribonuclease, and salivary ribonuclease levels in children with cystic fibrosis and in heterozygous carriers.
Ribonuclease and its inhibitor in red blood cells in CF.
Ribonuclease in different types of saliva from cystic fibrosis patients.
Salivary ribonuclease in cystic fibrosis and control subjects.
Serum ribonuclease levels in patients with cystic fibrosis.
[Determination of the ribonuclease activity of the duodenal contents of children as a test in the differential diagnosis of cystic fibrosis and pancreatic exocrine insufficiency]
Cystitis
Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction.
Dehydration
Ribonuclease Activity of Stressed Tomato Leaflets.
Dementia
Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia.
Dengue
A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor.
Dental Plaque
[Cooperation of antigens, immunoglobulins, complement and antimicrobial enzymes in the regulation of blood granulocyte locomotion]
Dermatitis, Atopic
RNase 7 Strongly Promotes TLR9-Mediated DNA Sensing by Human Plasmacytoid Dendritic Cells.
Diabetes Mellitus, Experimental
[Ribonuclease activity following partial hepatectomy in the liver of healthy and alloxan diabetic rats and histological findings in the islets of Langerhans (author's transl)]
Diabetes Mellitus, Type 2
Muscle Rad expression and human metabolism: potential role of the novel Ras-related GTPase in energy expenditure and body composition.
Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus.
DiGeorge Syndrome
Processing of virus-derived cytoplasmic primary-microRNAs.
Diphtheria
The second intron of AGAMOUS drives carpel- and stamen-specific expression sufficient to induce complete sterility in Arabidopsis.
Dysentery
[Ribonuclease activity of saliva in healthy persons, stomach cancer, food poisoning and bacterial dysentery]
Edema, Cardiac
Targeting of Extracellular RNA Reduces Edema Formation and Infarct Size and Improves Survival After Myocardial Infarction in Mice.
Encephalitis
Artificial ribonucleases inactivate a wide range of viruses using their ribonuclease, membranolytic, and chaotropic-like activities.
Chemokines are differentially expressed by astrocytes, microglia and inflammatory leukocytes in Toxoplasma encephalitis and critically regulated by interferon-gamma.
Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia.
Encephalitis, Japanese
Rana catesbeiana ribonuclease inhibits Japanese encephalitis virus (JEV) replication and enhances apoptosis of JEV-infected BHK-21 cells.
Encephalitis, Tick-Borne
Ribonuclease treatment of tick-borne encephalitis.
[Comparative effectiveness of ribonuclease and anti-encephalitis gamma globulin in tick-borne encephalitis]
[Dynamics of specific antibody accumulation in patients with tick-borne encephalitis following ribonuclease therapy]
[Experience with the etiotropic treatment of children with tick-bone encephalitis]
[Ribonuclease participation in the mechanism of the body's defense against viruses in tick-borne encephalitis]
[Ribonuclease therapy for tick-borne encephalitis]
[Use of ribonuclease in the treatment of tick-borne encephalitis]
Encephalomyelitis
In situ detection of autoreactive CD4 T cells in brain and heart using major histocompatibility complex class II dextramers.
Encephalomyelitis, Autoimmune, Experimental
Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis.
Endometrial Neoplasms
Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma.
Eosinophilia
Dissecting the role of eosinophil cationic protein in upper airway disease.
Telomerase activity in Hodgkin's disease.
Epilepsy, Reflex
Ribonuclease activity of brain homogenates of rats with audiogenic epilepsy.
Erythroblastosis, Fetal
[Value of determination of total protein content and ribonuclease activity in the amniotic fluid in the diagnosis of hemolytic disease of newborn]
Escherichia coli Infections
Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.
Foodborne Diseases
[Ribonuclease activity of saliva in healthy persons, stomach cancer, food poisoning and bacterial dysentery]
Foot-and-Mouth Disease
Ribonuclease activities associated with purified foot and mouth disease virus.
Ribonuclease contamination of crystalline deoxyribonclease, trypsin, and of partially purified foot-and-mouth disease virus preparations.
Genital Neoplasms, Female
[Serum ribonuclease activity in gynecologic neoplasms. The behavior of serum ribonuclease in ovarian cancer under cytostatic therapy]
Glioblastoma
Interleukin 1b and anaphylatoxins exert a synergistic effect on NGF expression by astrocytes.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
Glioma
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity.
Northern blot and ribonuclease protection study of alpha 2-adrenoceptor subtypes in cultured cell lines.
Glomerulonephritis
Expression and localization of inducible nitric oxide synthase in anti-Thy-1 glomerulonephritis.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
Goiter
[Serum ribonuclease activity in patients with simple or toxic goiter]
Granuloma
Involvement of ribonuclease in the interactions of macrophages and fibroblasts in experimental silicosis.
Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni.
Proinflammatory cytokines in granulomas associated with murine cysticercosis are not the cause of seizures.
Head and Neck Neoplasms
A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor.
Oral chemotherapy in head and neck cancer.
Heart Defects, Congenital
Induction of interleukin-8 messenger RNA in heart and skeletal muscle during pediatric cardiopulmonary bypass.
Heart Septal Defects, Ventricular
Expression of adenylyl cyclase V/VI mRNA and protein is upregulated in cyanotic infant human myocardium.
Hemorrhagic Septicemia, Viral
Analysis of the nucleoprotein gene identifies distinct lineages of viral haemorrhagic septicaemia virus within the European marine environment.
Hepatitis
Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.
[Ribonuclease activity of the liver and spleen during experimental mouse hepatitis caused by MHV-3 virus]
Hepatitis B
A ribonuclease H-oligo DNA conjugate that specifically cleaves hepatitis B viral messenger RNA.
Adenoviral-vector mediated transfer of HBV-targeted ribonuclease can inhibit HBV replication in vivo.
Effects of recombinant leukocyte interferon on ribonuclease activities in serum in chronic hepatitis B.
Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA.
Targeted ribonuclease can inhibit replication of hepatitis B virus.
Hepatitis B, Chronic
Effects of recombinant leukocyte interferon on ribonuclease activities in serum in chronic hepatitis B.
Hepatitis C
A ribonuclease protection assay for the direct detection and quantitation of hepatitis C virus RNA.
A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus.
Antiviral effect of ribonuclease conjugated oligodeoxynucleotides targeting the IRES RNA of the hepatitis C virus.
Inhibition of hepatitis C virus-directed gene expression by a DNA ribonuclease.
Structural domains of the 3'-terminal sequence of the hepatitis C virus replicative strand.
The ribonuclease L-dependent antiviral roles of human 2',5'-oligoadenylate synthetase family members against hepatitis C virus.
Herpes Simplex
Evidence for translational regulation by the herpes simplex virus virion host shutoff protein.
Herpes simplex virus 2 virion host shutoff protein interferes with type I interferon production and responsiveness.
Prediction of sequential antigenic regions in proteins.
The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formation.
The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin.
The roles of the cAMP-response element and TATA box in expression of the herpes simplex virus type 1 latency-associated transcripts.
Herpes Zoster
Downregulation of adrenal atrial natriuretic peptide receptor mRNAs and proteins by pregnancy in rats.
Hodgkin Disease
Complexing Rauscher leukemia virus reverse transcriptase with human plasma ribonuclease from Hodgkin's disease patients.
Telomerase activity in Hodgkin's disease.
Hydatidiform Mole
Use of a novel system for defining a gene imprinting region.
Hypersensitivity
Molecular study of hypersensitivity to spores in adults and children from Castile & Leon.
The determination of draining lymph node cell cytokine mRNA levels in BALB/c mice following dermal sodium lauryl sulfate, dinitrofluorobenzene, and toluene diisocyanate exposure.
Hypertension
Gene expression of vascular natriuretic peptide receptor in the aorta of hypertensive rats.
Parathyroid hormone-related peptide as a locally produced vasorelaxant: regulation of its mRNA by hypertension in rats.
Hyponatremia
Ectopic production and processing of atrial natriuretic peptide in a small cell lung carcinoma cell line and tumor from a patient with hyponatremia.
Ileus
[Changes in the activity of lysosomal enzymes in experimental ileus]
Infections
Alteration of cellular ribonucleases associated with murine oncogenic virus infection.
Alteration of human serum ribonuclease activity in malignancy.
Alternaria alternata Accelerates Loss of Alveolar Macrophages and Promotes Lethal Influenza A Infection.
Antiviral Activity of Binase against the Pandemic Influenza A (H1N1) Virus.
Cell fusing agent virus and dengue virus mutually interact in Aedes aegypti cell lines.
Changes in Two Ribonuclease Isozymes During Rust Infection of Flax Cotyledons.
Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo.
Conservation of DNA sequence in the predicted major late promoter regions of selected mastadenoviruses.
Deletion of the virion host shut-off gene of pseudorabies virus results in selective upregulation of the expression of early viral genes in the late stage of infection.
Down-regulation of the M6P/IGF-II receptor increases cell proliferation and reduces apoptosis in neonatal rat cardiac myocytes.
Fetal-maternal HLA-A and -B discordance is associated with placental RNase expression and anti-HIV-1 activity.
Fg12 ribonuclease secretion contributes to Fusarium graminearum virulence and induces plant cell death.
Formation in the dark, of virus-induced deoxyribonuclease activity in Anacystis nidulans, an obligate photoautotroph.
Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence.
Genetic analyses of the FRNK motif function of turnip mosaic virus uncover multiple and potentially interactive pathways of cross-protection.
Influenza A virus protein PA-X suppresses host Ankrd17-mediated immune responses.
Phosphatidylcholine-specific phospholipase C but not gamma interferon regulate gene expression and secretion of CC Chemokine Ligand-2 (CCL-2) by human astrocytes during infection by Toxoplasma gondii.
Preparation and Evaluation of Ribonuclease-Resistant Viral HIV RNA Standards Based on Armored RNA Technology
Profile of small interfering RNAs from cotton plants infected with the polerovirus Cotton leafroll dwarf virus.
Reactions of tobacco genotypes with different antioxidant capacities to powdery mildew and Tobacco mosaic virus infections.
Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.
Ribonuclease 7, an antimicrobial peptide upregulated during infection, contributes to microbial defense of the human urinary tract.
RNAi-associated ssRNA-specific ribonucleases in Tombusvirus P19 mutant-infected plants and evidence for a discrete siRNA-containing effector complex.
RNase 7 but not psoriasin nor sPLA2-IIA associates with Mycobacterium tuberculosis during airway epithelial cell infection.
RNASEK is required for internalization of diverse acid-dependent viruses.
Simian virus 40-infected, interferon-treated cells contain 2',5'-oligoadenylates which do not activate cleavage of RNA.
Targeted ribonuclease can inhibit replication of hepatitis B virus.
The antiviral activity of ribosomal polynucleotides against encephalomyocarditis virus infection of mice.
The bacteriophage T4 regB ribonuclease. Stimulation of the purified enzyme by ribosomal protein S1.
The effect of ribonuclease on the penetration of R17 phage A-protein and RNA.
The Escherichia coli prr region encodes a functional type IC DNA restriction system closely integrated with an anticodon nuclease gene.
Urine concentrations of human beta-defensins and ribonuclease 7 in urinary tract infection and asymptomatic bacteriuria.
[Construction and expression of prokaryotic expression vector for pTAT-HBV targeted ribonuclease fusion protein]
[The ribonuclease activity of bacteria as a factor in the persistence of the causative agents of sapronotic infections]
Infectious Mononucleosis
[Ribonuclease treatment of infectious mononucleosis in children]
Infertility
Ribonuclease 7, an antimicrobial peptide upregulated during infection, contributes to microbial defense of the human urinary tract.
Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract.
The second intron of AGAMOUS drives carpel- and stamen-specific expression sufficient to induce complete sterility in Arabidopsis.
Infertility, Male
Expression of Engineered Nuclear Male Sterility in Brassica napus (Genetics, Morphology, Cytology, and Sensitivity to Temperature).
Nuclear male sterility induced by pollen-specific expression of a ribonuclease.
RTS, a rice anther-specific gene is required for male fertility and its promoter sequence directs tissue-specific gene expression in different plant species.
Inflammatory Bowel Diseases
Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.
Influenza in Birds
[Preparation and antiviral properties of Bacillus intermedius ribonuclease modified by chloranhydride of adamantanecarboxylic acid]
Influenza, Human
Action of ribonuclease on the multiplication of the influenza virus.
Alternaria alternata Accelerates Loss of Alveolar Macrophages and Promotes Lethal Influenza A Infection.
Anti-Influenza Activity of the Ribonuclease Binase: Cellular Targets Detected by Quantitative Proteomics.
Association of a ribonuclease with the purified influenza virus.
Bacterial ribonuclease binase exerts an intra-cellular anti-viral mode of action targeting viral RNAs in influenza a virus-infected MDCK-II cells.
Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression.
Design, RNA cleavage and antiviral activity of new artificial ribonucleases derived from mono-, di- and tripeptides connected by linkers of different hydrophobicity.
Effects of ribonuclease and deoxyribonuclease on a murine leukemia virus (Rauscher).
Glycosylation: heterogeneity and the 3D structure of proteins.
Influenza A virus protein PA-X suppresses host Ankrd17-mediated immune responses.
The action of ribonuclease on the multiplication of influenza viruses in the de-embryonated egg.
The inaccessibility of genetically active but noninfective influenza virus to the intracellular action of ribonuclease.
The isolation and properties of a ribonuclease associated with influenza virus.
The matrix 1 protein of influenza A virus inhibits the transcriptase activity of a model influenza reporter genome in vivo.
[Reproduction of influenza virus with the aid of viral ribonucleic acid. IV. Investigation of ribonuclease in embryonated eggs of various ages.]
Insulin Resistance
Insulin receptor messenger ribonucleic acid sequence alterations detected by ribonuclease cleavage in patients with syndromes of insulin resistance.
Keloid
Elevated interleukin-6 expression in keloid fibroblasts.
Keratosis, Actinic
The expression of antimicrobial peptides is significantly altered in cutaneous squamous cell carcinoma and precursor lesions.
Kidney Failure, Chronic
Effect of hemodialysis on acid leukocyte-type ribonuclease, alkaline ribonuclease and polymorphonuclear elastase serum levels in patients with end-stage renal disease.
Zinc metabolism in uremia.
Kidney Neoplasms
A phase II trial of weekly intravenous ranpirnase (Onconase), a novel ribonuclease in patients with metastatic kidney cancer.
Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay.
Kwashiorkor
The activity of serum ribonuclease in protein-energy malnutrition.
Leukemia
A novel ribonuclease with antiproliferative activity toward leukemia and lymphoma cells and HIV-1 reverse transcriptase inhibitory activity from the mushroom, Hohenbuehelia serotina.
Alteration of cellular ribonucleases associated with murine oncogenic virus infection.
Complexing Rauscher leukemia virus reverse transcriptase with human plasma ribonuclease from Hodgkin's disease patients.
Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides.
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Effects of ribonuclease and deoxyribonuclease on a murine leukemia virus (Rauscher).
Elevated expression of the c-fes proto-oncogene in adult human myeloid leukemia cells in the absence of gene amplification.
Elevated ribonuclease activity in the thymus and white blood cells of genetically cancer prone mice.
Footprint analysis of replicating murine leukemia virus reverse transcriptase.
Levels of serum ribonuclease as an indicator of renal insufficiency in patients with leukemia.
Na+ -phosphate cotransport in mouse distal convoluted tubule cells: evidence for Glvr-1 and Ram-1 gene expression.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
Value of ribonuclease and guanase activity for the diagnosis of leukemias.
[Clinical significance of serum ribonuclease (RNase) assay in acute leukemia]
[Variations of ribonuclease in the blood and in urine in various types of leukemia.]
Leukemia, Erythroblastic, Acute
Identification of a novel exon and spliced form of Duffy mRNA that is the predominant transcript in both erythroid and postcapillary venule endothelium.
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
Leukemia, Experimental
[Ribonuclease polymorphism in experimental leukemia]
Leukemia, Hairy Cell
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Leukemia, Lymphocytic, Chronic, B-Cell
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Ribonuclease deficiency in lymphocytes of patients with chronic lymphocytic leukemia (CLL).
Leukemia, Lymphoid
Elevated expression of the c-fes proto-oncogene in adult human myeloid leukemia cells in the absence of gene amplification.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Differences in distribution of ribonuclease isoenzymes in cytosol and granules in normal human granulocytes and in granulocytes of patients with chronic granulocytic leukemia (CGL).
Disorders of ribonuclease activity in chronic granulocytic leukemia.
Major interference from leukocytes in reverse transcription-PCR identified as neurotoxin ribonuclease from eosinophils: detection of residual chronic myelogenous leukemia from cell lysates by use of an eosinophil-depleted cell preparation.
Profiles of ribonuclease fractions in normal human polymorphonuclear neutrophilic leukocytes and in chronic granulocytic leukemia (CGL) leukocytes.
Studies on serum and urinary ribonuclease activity in subjects related to patients with chronic granulocytic leukemia.
The pathogenesis of chronic granulocytic leukemia in the light of studies of ribonuclease metabolism.
The properties of ribonucleases isolated from urine of patients with chronic granulocytic leukemia (CGL). II. Urinary acid ribonuclease.
The properties of ribonucleases isolated from urine of patients with chronic granulocytic leukemia. I. Urinary alkaline ribonuclease.
The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester.
[Antiheparin activity of myeloperoxidase and ribonuclease of leukocytes in chronic granulocytic leukemia]
[Studies of activity of ribonuclease in the serum and urine in subjects genetically related to patients with chronic granulocytic leukemia]
[Studies on the pathogenesis of chronic granulocytic leukemias with special reference to the role of ribonuclease.]
[The properties of ribonucleases isolated from urine of patients with chronic granulocytic leukemia (CGL). I. Urinary alkaline ribonuclease (RNase)]
[The properties of ribonucleases isolated from urine of patients with chronic granulocytic leukemia (CGL). II. Urinary acid ribonuclease (RNase)]
Liver Abscess, Amebic
[Serum ribonuclease in hepatic amebiasis]
Liver Cirrhosis
[Expression of collagen XVIII mRNA in rat liver fibrosis]
Liver Diseases
Effects of chronic liver diseases on mitochondrial DNA transcription and replication in human liver.
Ribonuclease activities in liver tissue of patients with chronic liver diseases.
Liver Neoplasms
In vitro and in vivo anticarcinogenic effects of RNase MC2, a ribonuclease isolated from dietary bitter gourd, toward human liver cancer cells.
Recombinant hHscFv-RC-RNase protein derived from transgenic tobacco acts as a bifunctional molecular complex against hepatocellular carcinoma.
Liver Neoplasms, Experimental
Fidelity of synthesis of preribosomal RNA in isolated nucleoli and nucleolar chromatin.
Purification of a ribonuclease inhibitor from Novikoff hepatoma supernatant fraction.
Ribonuclease activity of ribonucleoprotein particles isolated from livers of rats fed 4-dimethylaminoazobenzene, primary liver tumors, and Novikoff hepatoma.
Structural analysis of nucleolar precursors of ribosomal ribonucleic acids. Sequence analysis of long oligonucleotides produced by T 1 ribonuclease digestion of nucleolar and ribosomal 28 S ribonucleic acid of Novikoff hepatoma ascites cells.
[Ribonuclease activity of ribosomes and nucleoli in experimental hepatomas and liver cells of healthy and tumor-bearing animals]
Lung Neoplasms
Carcinoma of the lung and cigarette smoking. Effect on serum ribonuclease activity.
Mechanisms of enhanced tumoricidal efficacy of multiple small dosages of ranpirnase, the novel cytotoxic ribonuclease, on lung cancer.
Lupus Erythematosus, Systemic
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
RNA-hydrolyzing antibodies from peripheral blood of patients with lupus erythematosus.
Lymphoma
A novel ribonuclease with antiproliferative activity toward leukemia and lymphoma cells and HIV-1 reverse transcriptase inhibitory activity from the mushroom, Hohenbuehelia serotina.
Different endocytic compartments are involved in the tight association of class II molecules with processed hen egg lysozyme and ribonuclease A in B cells.
Ribonucleases in mouse ascitic tumor cells during ageing in vivo and in vitro.
RNASET2 - An autoantigen in anaplastic large cell lymphoma identified by protein array analysis.
Lymphoma, B-Cell
Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma.
Lymphoma, Large-Cell, Anaplastic
RNASET2 - An autoantigen in anaplastic large cell lymphoma identified by protein array analysis.
Lymphoma, Non-Hodgkin
Changes in ribonuclease activities in P1798 lymphosarcoma after asparaginase treatment.
EFFECT OF CORTICOSTEROIDS ON RIBONUCLEASE AND NUCLEIC ACID CONTENT IN LYMPHOSARCOMA P1798.
Effect of starvation of intact and adrenalectomized mice bearing lymphosarcoma P1798 on tumor regression and ribonuclease activity.
Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma.
Ribonuclease inhibitor in lymphosarcoma P1798: effects of steroid and 5-FU.
The role of ribonuclease in regression of lymphosarcoma P1798.
Malnutrition
Serum ribonuclease activity in patients during parenteral nutrition, chronic hemodialysis and acute pancreatitis.
Medulloblastoma
Children's brain tumour cells produce RNA particles with incomplete retrovirus characteristics.
Melanoma
Effect of wheat leaf ribonuclease on tumor cells and tissues.
Genomic organization and chromosomal assignment of the human beta1, 4-N-acetylgalactosaminyltransferase gene. Identification of multiple transcription units.
MCPIP1 expression positively correlates with melanoma-specific survival of patients, and its overexpression affects vital intracellular pathways of human melanoma cells.
Mung bean sprout (Phaseolus aureus) nuclease and its biological and antitumor effects.
Plant ribonucleases and nucleases as antiproliferative agens targeting human tumors growing in mice.
Ribonuclease inhibitor up-regulation inhibits the growth and induces apoptosis in murine melanoma cells through repression of angiogenin and ILK/PI3K/AKT signaling pathway.
The JAK/STAT pathway is not sufficient to sustain the antiproliferative response in an interferon-resistant human melanoma cell line.
The structural organization of the human Na+/myo-inositol cotransporter (SLC5A3) gene and characterization of the promoter.
Up-regulating ribonuclease inhibitor inhibited epithelial-to-mesenchymal transition and metastasis in murine melanoma cells.
[Inhibitory effect of ginsenoside-Rg3 on lung metastasis of mouse melanoma transfected with ribonuclease inhibitor]
Melanoma, Experimental
Antitumor effects of human ribonuclease inhibitor gene transfected on B16 melanoma cells.
Inhibition of B16 melanoma growth in vivo by retroviral vector-mediated human ribonuclease inhibitor.
[Inhibitory effect of ginsenoside-Rg3 on lung metastasis of mouse melanoma transfected with ribonuclease inhibitor]
Meningioma
Growth hormone receptor expression and function in meningiomas: effect of a specific receptor antagonist.
Meningitis
[Ribonuclease activity in viral serous meningitis]
[Ribonuclease treatment of patients with viral serous meningitis]
[Treatment with ribonuclease of serous meningitis in children]
Mesothelioma
Antibody-targeted RNase fusion proteins (immunoRNases) for cancer therapy.
Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies.
Mesothelioma, Malignant
Combination of onconase and dihydroartemisinin synergistically suppresses growth and angiogenesis of non-small-cell lung carcinoma and malignant mesothelioma.
Cytostatic and cytotoxic properties of Amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes.
Designing hybrid onconase nanocarriers for mesothelioma therapy: a Taguchi orthogonal array and multivariate component driven analysis.
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity.
Interaction of onconase with the human ribonuclease inhibitor protein.
Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase.
Ranpirnase Interferes with NF-?B Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft Growth.
Ranpirnase--an antitumour ribonuclease: its potential role in malignant mesothelioma.
Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.
Mitochondrial Diseases
Mitochondrial tRNA cleavage by tRNA-targeting ribonuclease causes mitochondrial dysfunction observed in mitochondrial disease.
Mixed Connective Tissue Disease
Interstitial nephritis in a patient with atypical Sjögren's syndrome.
Mixed connective tissue disease.
Mouth Diseases
Ribonuclease activities associated with purified foot and mouth disease virus.
Multiple Myeloma
An assessment of the clinical usefulness of plasma ribonuclease assays.
Influence of renal insufficiency on levels of serum ribonuclease in patients with multiple myeloma.
Letter: Serum ribonuclease activity in multiple myeloma.
Serum ribonuclease in multiple myeloma.
Multiple Sclerosis
Intrathecal origin of CSF ribonuclease. Differences between infectious processes of the nervous system and multiple sclerosis.
Mumps
[Various mechanisms of the pathogenesis and etiotropic therapy of neurologic forms of epidemic parotitis]
Myocardial Infarction
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats.
Serum ribonuclease activity in acute myocardial infarction.
Serum ribonuclease activity in patients with myocardial infarction. I. Changes in the first three days of the disease.
[Ribonuclease (RNase) activity in blood serum of patients with myocardial infarction. I. The changes of activity during first three days of the disease]
Myocarditis
Characterization of cytokine and iNOS mRNA expression in situ during the course of experimental autoimmune myocarditis in rats.
Neoplasm Metastasis
Comparative study of proteome between primary cancer and hepatic metastatic tumor in colorectal cancer.
Crosstalk between NRF2 and Dicer through metastasis regulating MicroRNAs; Mir-34a, Mir-200 family and mir-103/107 family.
Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway.
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Knockdown of ribonuclease inhibitor expression with siRNA in non-invasive bladder cancer cell line BIU-87 promotes growth and metastasis potentials.
MicroRNA hsa-let-7e-5p as a potential prognosis marker for rectal carcinoma with liver metastases.
Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer.
Tumor and metastasis suppression by the human RNASET2 gene.
Up-regulating ribonuclease inhibitor inhibited epithelial-to-mesenchymal transition and metastasis in murine melanoma cells.
[Experiences with the tumor markers Ca 125 and plasma ribonuclease in ovarian cancer]
[Inhibitory effect of ginsenoside-Rg3 on lung metastasis of mouse melanoma transfected with ribonuclease inhibitor]
[Proteome study of colorectal cancer genesis and hepatic metastasis]
Neoplasms
"Plasma"-type ribonuclease in pancreatic cancer diagnosis: a critical appraisal.
111In-labelled octreotide binding by the somatostatin receptor subtype 2 in neuroendocrine tumours.
A Human Ribonuclease Variant and ERK-Pathway Inhibitors Exhibit Highly Synergistic Toxicity for Cancer Cells.
A multifunctional ribonuclease A-conjugated carbon dot cluster nanosystem for synchronous cancer imaging and therapy.
A novel human antitumor dimeric ImmunoRNase.
A novel somatic MAPK1 mutation in primary ovarian mixed germ cell tumors.
A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity.
A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells.
A phase II trial of weekly intravenous ranpirnase (Onconase), a novel ribonuclease in patients with metastatic kidney cancer.
A ribonuclease inhibitor expresses anti-angiogenic properties and leads to reduced tumor growth in mice.
A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells.
A ribonuclease specific for double-stranded RNA and two distinct ribonuclease H activities from the ribosomal salt wash fraction of Ehrlich ascites tumor cells.
A ribonuclease with antimicrobial, antimitogenic and antiproliferative activities from the edible mushroom Pleurotus sajor-caju.
A ribozyme specifically suppresses transformation and tumorigenicity of Ha-ras-oncogene-transformed NIH/3T3 cell lines.
Action of ribonuclease on certain ascites tumours.
Action of ribonuclease on neoplastic growth. I. Chemical aspects of normal tumour growth: the Landschütz ascites tumour.
Action of ribonuclease on two solid tumours in vivo.
Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase).
Activation of NF-kappaB-dependent gene expression by silica in lungs of luciferase reporter mice.
Adrenocortical carcinoma manifesting pure primary aldosteronism: a case report and analysis of steroidogenic enzymes.
Alkaline ribonuclease and ribonuclease inhibitor in mammary gland during the lactation cycle and in the R3230AC mammary tumour.
Alteration of cellular ribonucleases associated with murine oncogenic virus infection.
Alteration of human serum ribonuclease activity in malignancy.
Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer.
Angiogenin as a molecular target for the treatment of prostate cancer.
Angiogenin expression in head and neck basaloid and conventional squamous cell carcinoma: a site- and stage-matched comparison.
Angiogenin-mediated rRNA transcription in cancer and neurodegeneration.
Anti-gliomas Effect of Chlorotoxin-Conjugated Onconase at High Dose.
Anti-tumor effect in an in vivo model by human-derived pancreatic RNase with basic fibroblast growth factor insertional fusion protein through antiangiogenic properties.
Antitumor activity and toxicity of anti-HER2 immunoRNase scFv 4D5-dibarnase in mice bearing human breast cancer xenografts.
Antitumor effects of human ribonuclease inhibitor gene transfected on B16 melanoma cells.
Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning.
Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.
Biochemical analysis of secretory proteins synthesized by normal rat pancreas and by pancreatic acinar tumor cells.
c-myc, c-fos, and c-myb gene expression in human pituitary adenomas.
Catalytic Knockdown of miR-21 by Artificial Ribonuclease: Biological Performance in Tumor Model.
Cinacalcet attenuates hypercalcemia observed in mice bearing either Rice H-500 Leydig cell or C26-DCT colon tumors.
Combined action of 5-fluorouracil and other cytotoxic agents with crystalline ribonuclease on mouse ascites tumor.
Comparative study of proteome between primary cancer and hepatic metastatic tumor in colorectal cancer.
Comparison of secretory protein profiles in developing rat pancreatic rudiments and rat acinar tumor cells.
Construction of ribonuclease-antibody conjugates for selective cytotoxicity.
Contribution of the C30/C75 disulfide bond to the biological properties of onconase.
Cytostatic and cytotoxic properties of Amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes.
Design and Characterization of an HIV-Specific Ribonuclease Zymogen.
Design, characterization and anti-tumour cytotoxicity of a panel of recombinant, mammalian ribonuclease-based immunotoxins.
Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay.
DICER1-associated metastatic abdominopelvic primitive neuroectodermal tumor with an EWSR1 rearrangement in a 16-yr-old female.
DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. 3. Ribonuclease H and elongating activity of stimulatory factor S-II.
Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway.
Ectopic production and processing of atrial natriuretic peptide in a small cell lung carcinoma cell line and tumor from a patient with hyponatremia.
Effect of cimetidine on intratumoral cytokine expression in an experimental tumor.
Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II).
Effect of modification of the carboxyl groups of the sialic acid binding lectin from bullfrog (Rana catesbeiana) oocyte on anti-tumor activity.
Effect of Onconase on double-stranded RNA in vitro.
Effect of promoter and intron 2 polymorphisms on murine lung K-ras gene expression.
Effect of ribonuclease and deoxyribonuclease on incorporation of tritiated pyrimidine-nucleosides into ribonucleic acid and deoxyribonucleic acid in human cancer cells (HeLa) in culture.
Effect of ribonuclease on survival of ascites tumor bearing mice.
Effect of starvation of intact and adrenalectomized mice bearing lymphosarcoma P1798 on tumor regression and ribonuclease activity.
Effect of tumour growth on hepatic neutral ribonuclease and its inhibitor and on RNA polymerase activity of liver nuclei.
Effect of wheat leaf ribonuclease on tumor cells and tissues.
Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Efficient Intracellular Delivery of RNase A Using DNA Origami Carriers.
Efficient killing of CD22+ tumor cells by a humanized diabody-RNase fusion protein.
Elevated ribonuclease activity in the thymus and white blood cells of genetically cancer prone mice.
Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease.
Engineering the refolding pathway and the quaternary structure of seminal ribonuclease by newly introduced disulfide bridges.
Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease onconase (Ranpirnase).
Enzyme measurements in the investigation of pancreatic diseases.
Enzyme-free electrochemical biosensor based on double signal amplification strategy for the ultra-sensitive detection of exosomal microRNAs in biological samples.
Epidermal nucleases: purification and characterization of ribonuclease from mammalian epidermis.
Estrogen receptor expression in human pituitary: correlation with immunohistochemistry in normal tissue, and immunohistochemistry and morphology in macroadenomas.
Evolution of Molecularly Imprinted Enzyme Inhibitors: From Simple Activity Inhibition to Pathological Cell Regulation.
Exogenous nitric oxide donor and related compounds protect against lung inflammatory response after hemorrhagic shock and resuscitation.
Expression and characterization of a cytotoxic human-frog chimeric ribonuclease: potential for cancer therapy.
Expression and function of CXC and CC chemokines in human malignant liver tumors: a role for human monokine induced by gamma-interferon in lymphocyte recruitment to hepatocellular carcinoma.
Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma.
Expression of apoptosis-associated genes by human dermal scar fibroblasts.
Expression of chemokines and chemokine receptors during human renal transplant rejection.
Expression of toll-like receptor 4 and endotoxin responsiveness in mice during perinatal period.
Expression profiles of BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell lines.
Expression, Location, Clinical Implication, and Bioinformatics Analysis of RNASET2 in Gastric Adenocarcinoma.
Fetal and neoplastic expression of the neurotensin gene in the human colon.
Growth hormone receptor expression and function in meningiomas: effect of a specific receptor antagonist.
Human Cancer Antigen Globo H Is a Cell-Surface Ligand for Human Ribonuclease 1.
Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1.
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation.
Human ribonuclease with a pendant poly(ethylene glycol) inhibits tumor growth in mice.
Identification of germline and somatic mutations affecting the retinoblastoma gene.
Immunodetection of nmt55/p54nrb isoforms in human breast cancer.
Impact of antibody framework residue VH-71 on the stability of a humanised anti-MUC1 scFv and derived immunoenzyme.
In vitro and in vivo anticarcinogenic effects of RNase MC2, a ribonuclease isolated from dietary bitter gourd, toward human liver cancer cells.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
Induction of acute phase gene expression by brain irradiation.
Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase.
Induction of fibrinogen and a subset of acute phase response genes involves a novel monokine which is mimicked by phorbol esters.
Influence of age and N, N'-diethylene-N"-phenethyl-phosphoramide (PEDP) upon nucleic acid and ribonuclease activity in tumor tissue.
Influence of nutritional status on circulatory ribonuclease C levels in patients with cancer.
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells.
Inhibition of apoptosis in human neutrophils by Helicobacter pylori water-soluble surface proteins.
Inhibition of protein synthesis in a polyribosome-dependent cell-free system by a specific ribonuclease prepared from the follicles of two different stages of development of the silkmothAntherea pernyi.
Inhibition of telomerase by site-specific ribonucleases in gastric and esophageal adenocarcinoma.
Inhibition of tumor cell proliferation by dimerized ribonuclease.
Interaction of onconase with the human ribonuclease inhibitor protein.
Invitro synergism between a novel amphibian oocytic ribonuclease (onconase(r)) and tamoxifen, lovastatin and Cisplatin, in human ovcar-3 ovarian-carcinoma cell-line.
Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms.
Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity.
KFERQ sequence in ribonuclease A-mediated cytotoxicity.
Killing of cancer cells through the use of eukaryotic expression vectors harbouring genes encoding nucleases and ribonuclease inhibitor.
Landes Highlights.
Large-scale preparation of a ribonuclease from Rana catesbeiana (bullfrog) oocytes and characterization of its specific cytotoxic activity against tumor cells.
Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo.
Mammalian Rh/T2/S-glycoprotein ribonuclease family genes: cloning of a human member located in a region of chromosome 6 (6q27) frequently deleted in human malignancies.
Mammary tumor regression. V. Role of acid ribonuclease and cathepsin.
Mammary tumor regression. VI. Synthesis and degradation of acid ribonuclease.
Mast cell activation triggers a urothelial inflammatory response mediated by tumor necrosis factor-alpha.
MCPIP1 expression positively correlates with melanoma-specific survival of patients, and its overexpression affects vital intracellular pathways of human melanoma cells.
MCPIP1 ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells.
Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators.
MicroRNA hsa-let-7e-5p as a potential prognosis marker for rectal carcinoma with liver metastases.
Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase.
Multiple epithelial cell-derived factors enhance neutrophil survival. Regulation by glucocorticoids and tumor necrosis factor-alpha.
Mung bean sprout (Phaseolus aureus) nuclease and its biological and antitumor effects.
Murine complement C4 is not required for experimental autoimmune encephalomyelitis.
Non-specificity of elevated serum ribonuclease as a pancreatic tumour marker.
Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector.
Nuclear EGFR Suppresses Ribonuclease Activity of Polynucleotide Phosphorylase through DNAPK-mediated Phosphorylation at Serine 776.
On the track of antitumour ribonucleases.
Ovarian carcinoma: increase in clinical validity by simultaneous determination of SRA and CA 125.
Pancreatic-like ribonuclease activity in the ascites fluid of the Novikoff and Ehrlich tumors.
Plant ribonucleases and nucleases as antiproliferative agens targeting human tumors growing in mice.
Plasmacytoid differentiation of Epstein-Barr virus-transformed B cells in vivo is associated with reduced expression of viral latent genes.
Poly (C) avid ribonuclease estimation in patients with solid tumors. A critical evaluation.
Polyribosomes in tumor cells during induction of ribonuclease by cytostatic treatment.
Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer.
Potentiation of tumor necrosis factor induced apoptosis by onconase.
Promoter-specific transcription of the IGF2 gene: a novel rapid, non-radioactive and highly sensitive protocol for mRNA analysis.
Purification and properties of a novel nucleolar exoribonuclease capable of degrading both single-stranded and double-stranded RNA.
Purine-binding factor (nm23) gene expression in pituitary tumors: marker of adenoma invasiveness.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
Ranpirnase (Onconase), a cytotoxic amphibian ribonuclease, manipulates tumour physiological parameters as a selective killer and a potential enhancer for chemotherapy and radiation in cancer therapy.
Ranpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies.
Ranpirnase: amphibian ribonuclease A, P-30 protein-alfacell.
Recombinant expression, different downstream processing of the disulfide-rich anti-tumor peptide Ranpirnase and its effect on the growth of human glioma cell line SHG-44.
Reduction of tumorigenicity of SMMC-7721 hepatoma cells by vascular endothelial growth factor antisense gene therapy.
Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.
Retinoic acids and thyroid hormone act synergistically with dexamethasone to increase growth hormone-releasing hormone receptor messenger ribonucleic acid expression.
Ribonuclease activity and cancer: a review.
Ribonuclease activity and ribonucleic acid content of homologous human normal and cancer cells.
Ribonuclease activity in the Ehrlich ascites tumour.
Ribonuclease activity of ribonucleoprotein particles isolated from livers of rats fed 4-dimethylaminoazobenzene, primary liver tumors, and Novikoff hepatoma.
Ribonuclease and deoxyribonuclease activites in experimental and human tumors by the histochemical substrate film method.
Ribonuclease as a tumour marker for pancreatic carcinoma.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Ribonucleases and their antitumor activity.
Ribonucleases as novel chemotherapeutics : the ranpirnase example.
Ribonucleases expressed by human pancreatic adenocarcinoma cell lines.
Ribonucleoprotein from a rat tumor, the Jensen sarcoma. III. Ribosomes purified without deoxycholate but with bentonite as ribonuclease inhibitor.
RNA cleavage and inhibition of protein synthesis by bleomycin.
RNASET2 - An autoantigen in anaplastic large cell lymphoma identified by protein array analysis.
Role of metallothionein-III following central nervous system damage.
Role of the N terminus in RNase A homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity.
Rutamarin, an Active Constituent from Ruta angustifolia Pers., Induced Apoptotic Cell Death in the HT29 Colon Adenocarcinoma Cell Line.
Sensitive detection of clonal antigen receptor gene rearrangements for the diagnosis and monitoring of lymphoid neoplasms by a polymerase chain reaction-mediated ribonuclease protection assay.
SERUM LACTIC DEHYDROGENASE AND RIBONUCLEASE IN THE DIAGNOSIS OF MALIGNANT TUMOURS IN CHILDREN.
Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma.
Serum ribonuclease activity in cancer patients.
Serum ribonuclease activity in patients with ovarian tumors.
Serum ribonuclease activity in the diagnosis of prostate cancer in men with serum prostate-specific antigen levels between 2.5 and 20 ng/mL.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
SERUM RIBONUCLEASE DURING THE PROCESS OF DAB CARCINOGENESIS AND TUMOR GROWTH.
Serum ribonuclease in the diagnosis of pancreatic carcinoma and in monitoring chemotherapy.
Small Molecule Targeted Recruitment of a Nuclease to RNA.
Stressing out over tRNA cleavage.
Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.
Synergism of Rana catesbeiana ribonuclease and IFN-gamma triggers distinct death machineries in different human cancer cells.
Temporal changes in cytokine expression of foals during the first month of life.
Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features of DICER1 syndrome.
The cytotoxic ribonuclease onconase targets RNA interference (siRNA).
The Cytotoxicity of RNase-Derived Peptides.
The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas.
The insecticidal protein hirsutellin A from the mite fungal pathogen Hirsutella thompsonii is a ribotoxin.
The Rana catesbeiana rcr gene encoding a cytotoxic ribonuclease. Tissue distribution, cloning, purification, cytotoxicity, and active residues for RNase activity.
The role of angiogenin in pT1-T2 tongue carcinoma neo-angiogenesis and cell proliferation: an exploratory study.
The widespread human desmocollin Dsc2 and tissue-specific patterns of synthesis of various desmocollin subtypes.
Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma.
Transcription of angiogenin and ribonuclease 4 is regulated by RNA Polymerase III elements and a CCCTC-binding factor (CTCF)-dependent intragenic chromatin loop.
Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2.
Transcriptomic alterations in malignant pleural mesothelioma cells in response to long?term treatment with bullfrog sialic acid?binding lectin.
Translin-Trax: Considerations for Oncological Therapeutic Targeting.
TREATMENT OF EXPERIMENTAL ASCITES TUMORS WITH CRYSTALLINE RIBONUCLEASE.
Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-kappaB.
Tumor and metastasis suppression by the human RNASET2 gene.
Unique recombinant human ribonuclease and inhibition of Kaposi's sarcoma cell growth.
VEGF-B expression in human primary breast cancers is associated with lymph node metastasis but not angiogenesis.
X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.
Zinc-alpha(2)-glycoprotein hinders cell proliferation and reduces cdc2 expression.
[Action of ribonuclease and desoxyribonuclease on the incorporation of L-glutamic acid U-C-14 and methionine S-35 in tumor cells of Ehrlich's ascites carcinoma]
[Bacillus pumilus Ribonuclease Inhibits Migration of Human Duodenum Adenocarcinoma HuTu 80 Cells].
[Biochemical and histochemical study of nucleic acids and the enzymes depolymerizing them in cancerous tumor of the larynx before and after the effect of ribonuclease]
[Changes in ribonuclease activity in the serum and urine in surgical cases of cancer of the digestive tract and other diseases. 1]
[Changes in serum and urinary ribonuclease activities in various diseases with special reference to surgical cases of digestive organ tumors]
[Changes in serum and urinary ribonuclease activity in surgically treated cases of digestive organ tumors and various other diseases]
[Changes of plasma ribonuclease activities according to the method of treatment in gynecologic cancer patients (author's transl)]
[Effect of Bacillus pumilus ribonuclease on the paramagnetic centers of microbial cells].
[Effect of ribonuclease on cell cycle dynamics in tumor cells in vitro and in vivo]
[Effective expression of ribonuclease-onconase in Escherichia coli and assaying its cytotoxic potential]
[Experiences with the tumor markers Ca 125 and plasma ribonuclease in ovarian cancer]
[Influence of ribonuclease on experimental tumor growth]
[Mechanisms of the effect of polyamines on the complex-forming ability of blood plasma ribonucleases]
[On the effect of cytostatic compounds and nicotinic acid amide on ascites tumor ribonuclease (n).]
[ON THE LOCALIZATION OF RIBONUCLEASE (RNASE) AND DESOXYRIBONUCLEASE (DNASE) ACTIVITY IN NORMAL AND INFLAMED SKIN AND IN SKIN TUMORS.]
[Proteome study of colorectal cancer genesis and hepatic metastasis]
[Reversible injuries of the natural killer cell membrane after contact with tumor cells]
[Ribonuclease activity & ribonucleic acid content of normal tissues & neoplasms.]
[Ribonuclease activity in the nervous system and its tumors]
[Secretory expression vector V-pLNCX-s-hri inhibits the growth of mouse B16 melanoma.]
[Serum ribonuclease activity in gynecologic neoplasms. The behavior of serum ribonuclease in ovarian cancer under cytostatic therapy]
[Serum ribonuclease activity in the diagnosis of malignant neoplasms (author's transl)]
[Serum ribonuclease and beta-glucuronidase activity in patients with malignant ovarian tumors treated surgically and followed up with combined chemotherapy]
[Serum ribonuclease and its importance for renal diagnosis (author's transl)]
[Serum ribonuclease in patients with malignant tumor of the ovary]
[Study of ribonuclease absorption by bone marrow cells & by ascites tumor cells.]
[Study on ribonuclease activity in tissues of human colonorectal mucosa using synthetic substrate--activity in normal mucosa, cancer tissue and inflammatory mucosa of ulcerative colitis]
[Transplantation of ascites tumor cells pretreated with ribonuclease and phytohemagglutinin]
[Value of plasma ribonuclease as a marker for gynecologic tumors and breast tumors]
Neoplasms, Germ Cell and Embryonal
A novel somatic MAPK1 mutation in primary ovarian mixed germ cell tumors.
Nephritis
Changes in the pattern of fibronectin mRNA alternative splicing in acute experimental mesangioproliferative nephritis.
Nephrosis
Coxsackievirus and adenovirus receptor, a tight junction membrane protein, is expressed in glomerular podocytes in the kidney.
Role of Fat1 in cell-cell contact formation of podocytes in puromycin aminonucleoside nephrosis and neonatal kidney.
Up-regulation of connexin43 in glomerular podocytes in response to injury.
Nephrotic Syndrome
Purification and properties of urinary alkaline ribonucleases from patients with nephrotic syndrome.
Nervous System Diseases
[Use of ribonuclease and desoxyribonuclease in several chronic nervous system diseases of viral etiology]
Neuroblastoma
MCPIP1 ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells.
Northern blot and ribonuclease protection study of alpha 2-adrenoceptor subtypes in cultured cell lines.
Neurodegenerative Diseases
Angiogenin and tRNA fragments in Parkinson's disease and neurodegeneration.
G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments.
Rare Angiogenin and Ribonuclease 4 variants associated with amyotrophic lateral sclerosis exhibit loss-of-function: a comprehensive in silico study.
Transcription of angiogenin and ribonuclease 4 is regulated by RNA Polymerase III elements and a CCCTC-binding factor (CTCF)-dependent intragenic chromatin loop.
Obesity
Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus.
Osteoporosis
[Effect of ribonuclease on the development of experimental osteoporosis in animals of various ages]
Ovarian Neoplasms
Bacillus intermedius ribonuclease (BINASE) induces apoptosis in human ovarian cancer cells.
Effect of Cytostatic Drugs on the mRNA Expression Levels of Ribonuclease k in Breast and Ovarian Cancer Cells.
Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line.
[Determination of the plasma ribonuclease activity as a diagnostic aid in the diagnosis of ovarian cancer. Results of a double blind study (author's transl)]
[Experiences with the tumor markers Ca 125 and plasma ribonuclease in ovarian cancer]
[Serum ribonuclease activity in gynecologic neoplasms. The behavior of serum ribonuclease in ovarian cancer under cytostatic therapy]
Pancreatic Diseases
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Serum ribonuclease activity in the diagnosis of pancreatic disease.
Urinary elastase 1 in chronic pancreatic disease.
Urinary ribonuclease excretion in pancreatic disease.
[Studies on ribonuclease in the pancreatic juice of patient with pancreatic disease. II. Secretory pattern of ribonuclease, amylase and immunoreactive trypsin in duodenal juice during pancreozymin secretin test]
[Studies on ribonucleases in the pancreatic juice of patients with pancreatic disease. I. Ribonuclease assay, effect of storing samples and isolation of the ribonucleases in pure pancreatic juice (author's transl)]
Pancreatic Neoplasms
"Plasma"-type ribonuclease in pancreatic cancer diagnosis: a critical appraisal.
Assessment of the clinical usefulness of serum ribonuclease assays: an indicator for the detection of pancreatic cancer.
Butyrate inhibits pancreatic cancer invasion.
Combined evaluation of serum ribonuclease and ferritin: any advantages in pancreatic cancer diagnosis?
Elevated serum ribonuclease in patients with pancreatic cancer.
Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.
IIIc isoform of fibroblast growth factor receptor 1 is overexpressed in human pancreatic cancer and enhances tumorigenicity of hamster ductal cells.
Non-specificity of elevated serum ribonuclease as a pancreatic tumour marker.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Renal tubular dysfunction in pancreatic cancer and chronic pancreatitis.
Ribonuclease and ribonuclease inhibitor in the human pancreas.
Ribonuclease C and pancreatic secretory proteins in the peripheral circulation before and after pancreatectomy for pancreatic cancer.
Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells.
Ribonucleases expressed by human pancreatic adenocarcinoma cell lines.
Sensitivity and specificity of serum ribonuclease in the diagnosis of pancreatic cancer.
Serum deoxyribonuclease and ribonuclease in pancreatic cancer and chronic pancreatitis.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
Serum RNase in the diagnosis of pancreatic carcinoma.
Urinary elastase 1 in chronic pancreatic disease.
Urinary ribonuclease excretion in pancreatic disease.
[Diagnostic significance of serum ribonuclease determination in the pancreatic cancer (author's transl)]
[Study of mechanisms of increasing serum RNase]
[The activity of serum ribonuclease in pancreatic cancer]
pancreatic ribonuclease deficiency
Ribonuclease deficiency in lymphocytes of patients with chronic lymphocytic leukemia (CLL).
Tiny abortive initiation transcripts exert antitermination activity on an RNA hairpin-dependent intrinsic terminator.
Pancreatitis
Biochemical studies in peritoneal fluid from patients with acute pancreatitis. Relationship to etiology.
Comparison of sensitivity and specificity of serum poly-C avid ribonuclease activity and C-reactive protein concentration in detection of mild and severe acute pancreatitis.
Determination of ribonuclease activity in serum of patients with pancreatic necrosis. An attempt of extending the enzyme diagnosis of acute pancreatitis.
Glutamate cysteine ligase up-regulation fails in necrotizing pancreatitis.
Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: Involvement of cyclooxygenases and heat shock protein 70.
Poly-C specific ribonuclease activity correlates with increased concentrations of IL-6, IL-8 and sTNFR55/sTNFR75 in plasma of patients with acute pancreatitis.
Relationship between pancreatic enzymes and pathological changes in the pancreas in acute pancreatitis. The significance of determination of serum deoxyribonuclease.
Serum ribonuclease activity in patients during parenteral nutrition, chronic hemodialysis and acute pancreatitis.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
Serum ribonuclease elevations and pancreatic necrosis in acute pancreatitis.
Serum RNase in the diagnosis of pancreatic carcinoma.
The endogenous scavengers in cerulein-induced acute pancreatitis.
The proteome of mesenteric lymph during acute pancreatitis and implications for treatment.
[Individual choice of ribonuclease and fluorofur doses in the treatment of patients with acute pancreatitis]
[Ribonuclease in the experimental therapy of pancreatitis]
[Ribonuclease in the treatment of acute pancreatitis]
[Use of ribonuclease in multimodal treatment of acute pancreatitis]
[Use of ribonuclease in treatment of acute experimental pancreatitis]
Pancreatitis, Acute Necrotizing
Determination of ribonuclease activity in serum of patients with pancreatic necrosis. An attempt of extending the enzyme diagnosis of acute pancreatitis.
Poly-C specific ribonuclease activity correlates with increased concentrations of IL-6, IL-8 and sTNFR55/sTNFR75 in plasma of patients with acute pancreatitis.
Serum ribonuclease elevations and pancreatic necrosis in acute pancreatitis.
Pancreatitis, Chronic
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Renal tubular dysfunction in pancreatic cancer and chronic pancreatitis.
Serum deoxyribonuclease and ribonuclease in pancreatic cancer and chronic pancreatitis.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
Serum ribonuclease in the diagnosis of pancreatic carcinoma and in monitoring chemotherapy.
Urinary elastase 1 in chronic pancreatic disease.
Urinary ribonuclease excretion in pancreatic disease.
[Ribonuclease in the experimental therapy of pancreatitis]
Papilloma
RIBONUCLEASE AND DEOXYRIBONUCLEASE ACTIVITIES IN RAT AND MOUSE STRATIFIED SQUAMOUS EPITHELIA AND SKIN PAPILLOMAS.
Survivin expression in juvenile-onset recurrent respiratory papillomatosis.
Paralysis
Artificial ribonucleases inactivate a wide range of viruses using their ribonuclease, membranolytic, and chaotropic-like activities.
Parasitic Diseases
Activity of some hydrolytic enzymes in tissue homogenates and haemolymph of fresh water snails, intermediate hosts in schistosomiasis.
Parathyroid Neoplasms
Vitamin D receptor (VDR) and parathyroid hormone messenger ribonucleic acid levels correspond to polymorphic VDR alleles in human parathyroid tumors.
Parkinson Disease
Angiogenin and tRNA fragments in Parkinson's disease and neurodegeneration.
Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia.
peptide-n4-(n-acetyl-beta-glucosaminyl)asparagine amidase deficiency
High-throughput protein modification quantitation analysis using intact protein MRM and its application on hENGase inhibitor screening.
Periodontal Diseases
[The use of ribonuclease in the treatment of early stages of parodontosis]
Peritonitis
Analysis of the Ribonuclease A Superfamily of Antimicrobial Peptides in Patients Undergoing Chronic Peritoneal Dialysis.
Persistent Infection
Structures and Functions of Pestivirus Glycoproteins: Not Simply Surface Matters.
Pinealoma
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.
Pituitary Neoplasms
c-myc, c-fos, and c-myb gene expression in human pituitary adenomas.
Estrogen receptor expression in human pituitary: correlation with immunohistochemistry in normal tissue, and immunohistochemistry and morphology in macroadenomas.
Pleural Effusion, Malignant
Ribonuclease at pH5 in malignant pleural effusion.
Pneumonia
Diminished expression of an antiviral ribonuclease in response to pneumovirus infection in vivo.
T(H)2-mediated pulmonary inflammation leads to the differential expression of ribonuclease genes by alveolar macrophages.
[Use of pentoxyl and ribonuclease in the overall treatment of young children with pneumonia]
Pneumovirus Infections
Diminished expression of an antiviral ribonuclease in response to pneumovirus infection in vivo.
Poliomyelitis
Correlation of beta-bend conformations of tetrapeptides with their activities in CD4-receptor binding assays.
[Interference of ribonuclease with multiplication of poliomyelitis virus in cell cultures in vitro.]
Prostatic Neoplasms
2'-5' oligoadenylate synthetase 1 polymorphism is associated with prostate cancer.
Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells.
Angiogenin as a molecular target for the treatment of prostate cancer.
Angiogenin-stimulated rRNA transcription is essential for initiation and survival of AKT-induced prostate intraepithelial neoplasia.
Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase.
Effect of homeopathic treatment on gene expression in Copenhagen rat tumor tissues.
Enzyme markers in human prostatic carcinoma.
Immunological similarities between cancer and chronic fatigue syndrome: the common link to fatigue?
In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene.
Mechanism and Function of Angiogenin in Prostate Cancer.
Microarray analysis of differential gene expression in androgen independent prostate cancer using a metastatic human prostate cancer cell line model.
Protein kinase C mu is down-regulated in androgen-independent prostate cancer.
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases.
RNASEL germline variants are associated with pancreatic cancer.
Serum acid phosphohydrolase (phosphatase) and ribonuclease in diagnosis of prostatic cancer.
Serum ribonuclease activity in the diagnosis of prostate cancer in men with serum prostate-specific antigen levels between 2.5 and 20 ng/mL.
The role of inflammation in the pathogenesis of prostate cancer.
Protein Deficiency
An assessment of the clinical usefulness of plasma ribonuclease assays.
Serum ribonuclease activity in patients during parenteral nutrition, chronic hemodialysis and acute pancreatitis.
Protein-Energy Malnutrition
The activity of serum ribonuclease in protein-energy malnutrition.
Proteinuria
Further evidence for tubular dysfunction in insulin dependent diabetes.
Proteinuria and excretion of ribonuclease in patients with chronic granulocytic leukaemia.
Pseudohypoparathyroidism
Expression and modulation of the parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid in skin fibroblasts from patients with type Ib pseudohypoparathyroidism.
Psoriasis
RNase 7 Strongly Promotes TLR9-Mediated DNA Sensing by Human Plasmacytoid Dendritic Cells.
[RIBONUCLEIC ACID AND RIBONUCLEASE IN PSORIASIS SCALES.]
Pulmonary Disease, Chronic Obstructive
Expression of beta 2-adrenergic receptor mRNA in peripheral lung in asthma and chronic obstructive pulmonary disease.
Pulpitis
The effect of a proteolytic enzyem mixture (Orenzyme-Forte) on experimentally induced pulpitis.
Rabies
Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro.
[Ribonuclease effects on rabies fixed virus]
Renal Insufficiency
Acid ribonuclease and alkaline ribonuclease isoenzymes in plasma of patients with decreased glomerular filtration rate.
Influence of renal insufficiency on levels of serum ribonuclease in patients with multiple myeloma.
Levels of serum ribonuclease as an indicator of renal insufficiency in patients with leukemia.
Non-specificity of elevated serum ribonuclease as a pancreatic tumour marker.
Ribonuclease activity in renal failure. Evidence for toxicity.
Ribonuclease activity in renal failure: evidence for toxicity.
Ribonuclease inhibition of erythropoiesis in anemia of uremia.
Serum ribonuclease activity in dialyzed patients with terminal renal failure.
Serum ribonuclease of normal persons and patients with renal impairment.
Serum RNase in the diagnosis of pancreatic carcinoma.
Renal Insufficiency, Chronic
Diagnostic significance of different urinary enzymes in patients suffering from chronic renal diseases.
[The low molecular weight proteins ribonuclease, beta 2 microglobulin and lysozyme in the serum and urine of patients with chronic kidney diseases]
Reperfusion Injury
Ribonuclease alleviates hepatic ischemia-reperfusion injury by suppressing excessive cytokine release and TLR3-mediated apoptosis in mice.
Ribonuclease attenuates hepatic ischemia reperfusion induced cognitive impairment through the inhibition of inflammatory cytokines in aged mice.
Ribonuclease attenuates retinal ischemia reperfusion injury through inhibition of inflammatory response and apoptosis in mice.
Rhabdomyosarcoma, Embryonal
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Rheumatic Diseases
[Serum ribonuclease in rheumatic disease. I. Serum alkaline ribonuclease activities in rheumatic diseases, especially in malignant rheumatoid arthritis]
[Serum ribonuclease in rheumatic disease. II. Possible origin of alkaline ribonuclease from the vessels]
Rubella
Fate of rubella genome ribonucleic acid after immune and nonimmune virolysis in the presence of ribonuclease.
Sarcoma
Alteration of cellular ribonucleases associated with murine oncogenic virus infection.
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Human non-pregnancy ribonuclease with anti-Kaposi's sarcoma activity.
Interactions of histone, ribonuclease and acridine orange in enhancing film sarcoma.
Ribonuclease in Yoshida ascites sarcoma.
[Ribonuclease activity in normal rats and in rats with B 77 sarcoma.]
Sarcoma, Avian
Electron microscopy of Rous sarcoma virus genome RNA and its heat-dissociated subunits.
RNA-directed DNA synthesis by the DNA polymerase of Rous sarcoma virus: structural and functional identification of 4S primer RNA in uninfected cells.
Sequence specificity of internal methylation in B77 avian sarcoma virus RNA subunits.
Studies on the structure of avian myeloblastosis virus (AMV) RNA. III. Electron microscopic definition of secondary structure.
Sarcoma, Experimental
Ribonucleoprotein from a rat tumor, the Jensen sarcoma. III. Ribosomes purified without deoxycholate but with bentonite as ribonuclease inhibitor.
Sarcoma, Kaposi
Ribonuclease inhibits Kaposi's sarcoma.
Unique recombinant human ribonuclease and inhibition of Kaposi's sarcoma cell growth.
Schistosomiasis
Activity of some hydrolytic enzymes in tissue homogenates and haemolymph of fresh water snails, intermediate hosts in schistosomiasis.
Schistosomiasis mansoni
Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo.
Scleritis
Suppressor Of Cytokine Signaling-1 Inhibits Lymphocyte Recruitment into the Retina and Protects SOCS1 Transgenic Rats and Mice from Ocular Inflammation.
Scrapie
A novel replicating agent isolated from the human intestinal tract having characteristics shared with Creutzfeldt-Jakob and related agents.
Seizures
Biphasic response of hippocampal dynorphin expression following recurrent limbic seizure.
Differential regulation of catalytic and non-catalytic trkB messenger RNAs in the rat hippocampus following seizures induced by systemic administration of kainate.
Sepsis
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis.
Shock, Septic
Increased serum ribonuclease activity during endotoxin shock in rats.
Silicosis
Involvement of ribonuclease in the interactions of macrophages and fibroblasts in experimental silicosis.
Skin Neoplasms
MCPIP1 expression positively correlates with melanoma-specific survival of patients, and its overexpression affects vital intracellular pathways of human melanoma cells.
Spinal Cord Injuries
Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction.
Starvation
A Phosphate Starvation-Inducible Ribonuclease of Bacillus licheniformis.
Accumulation of nucleotides by starved Escherichia coli cells as a probe for the involvement of ribonucleases in ribonucleic acid degradation.
An S-like ribonuclease gene is used to generate a trap-leaf enzyme in the carnivorous plant Drosera adelae.
Attenuation of phosphate starvation responses by phosphite in Arabidopsis.
Conditional identification of phosphate-starvation-response mutants in Arabidopsis thaliana.
Effect of starvation of intact and adrenalectomized mice bearing lymphosarcoma P1798 on tumor regression and ribonuclease activity.
Induction of an Extracellular Ribonuclease in Cultured Tomato Cells upon Phosphate Starvation.
LEAF TIP NECROSIS 1 Plays a Pivotal Role in Regulation of Multiple Phosphate Starvation Responses in Rice.
Phosphate-Starvation-Inducible S-Like RNase Genes in Rice Are Involved in Phosphate Source Recycling by RNA Decay.
Physiological characterization of an Escherichia coli mutant altered in the structure of murein lipoprotein.
Starvation and ribonuclease activity in rat erythrocytes.
The involvement of ribonuclease I, ribonuclease II, and polynucleotide phosphorylase in the degradation of stable ribonucleic acid during carbon starvation in Escherichia coli.
Transcriptional analysis of the 16s rRNA gene in Rickettsia prowazekii.
Utilization of polyadenylate mRNA during growth and starvation in Physarum polycephalum.
Stomach Neoplasms
Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma.
Up-regulation and co-expression of fibroblast growth factor receptors in human gastric cancer.
[Ribonuclease activity of saliva in healthy persons, stomach cancer, food poisoning and bacterial dysentery]
Stroke
Extracellular RNAs as a chemical initiator for postoperative cognitive dysfunction.
RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation.
RNase therapy assessed by magnetic resonance imaging reduces cerebral edema and infarction size in acute stroke.
Teratocarcinoma
Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells.
Teratoma
Use of a novel system for defining a gene imprinting region.
Tuberculosis
Cloning, expression, purification and preliminary crystallographic analysis of the RNase HI domain of the Mycobacterium tuberculosis protein Rv2228c as a maltose-binding protein fusion.
Crystal structure of the VapBC-15 complex from Mycobacterium tuberculosis reveals a two-metal ion dependent PIN-domain ribonuclease and a variable mode of toxin-antitoxin assembly.
Effect of trypsin and ribonuclease on the immunogenic activity of ribosomes and ribonucleic acid isolated from Mycobacterium tuberculosis.
Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides.
Immunobiological studies with mycobacterial ribonucleic acid-protein complex: Part I--Immune responses and protective role against experimental tuberculosis.
Structural and dynamic studies provide insights into specificity and allosteric regulation of ribonuclease as, a key enzyme in mycobacterial virulence.
Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides.
VapC proteins from Mycobacterium tuberculosis share ribonuclease sequence specificity but differ in regulation and toxicity.
[On the possible role of ribonucleic acid in the mechanism of anti-tuberculosis resistance. II. Ribonucleic acid and ribonuclease activity in the organism of mice infected with tuberculosis and immunized with BCG vaccine.]
Uremia
Plasma ribonuclease activity in human uremia.
Ribonuclease inhibition of erythropoiesis in anemia of uremia.
Serum ribonuclease and its isoenzymes for diagnosis of pancreatic cancer.
Zinc deficiency: a reversible complication of uremia.
Urinary Bladder Neoplasms
A novel role of ribonuclease inhibitor in regulation of epithelial-to-mesenchymal transition and ILK signaling pathway in bladder cancer cells.
Angiogenin interacts with ribonuclease inhibitor regulating PI3K/AKT/mTOR signaling pathway in bladder cancer cells.
Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway.
High expression of Wnt7b in human superficial bladder cancer vs invasive bladder cancer.
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Knockdown of ribonuclease inhibitor expression with siRNA in non-invasive bladder cancer cell line BIU-87 promotes growth and metastasis potentials.
Urinary Tract Infections
Urine concentrations of human beta-defensins and ribonuclease 7 in urinary tract infection and asymptomatic bacteriuria.
Urologic Neoplasms
Serum ribonuclease in urologic cancer. Relation to host immunocompetence.
Uterine Cervical Neoplasms
Rana catesbeiana ribonuclease induces cell apoptosis via the caspase-9/-3 signaling pathway in human glioblastoma DBTRG, GBM8901 and GBM8401 cell lines.
Vaginal fluid ribonuclease activity in the diagnosis of cervical cancer.
Vaccinia
A freeze-frame view of eukaryotic transcription during elongation and capping of nascent mRNA.
Artificial ribonucleases inactivate a wide range of viruses using their ribonuclease, membranolytic, and chaotropic-like activities.
Inhibition of the vaccinia virus associated ribonuclease by Hela S3 cytosol.
Ribonuclease activity of vaccinia DNA topoisomerase IB: kinetic and high-throughput inhibition studies using a robust continuous fluorescence assay.
[Detection and localization of a ribonuclease activity associated with vaccinia virus]
Vesicular Stomatitis
Glycoprotein evolution of vesicular stomatitis virus New Jersey.
Mapping temperature-sensitive mutants of vesicular stomatitis virus by RNA heteroduplex formation.
Mycoplasmas produce double-stranded ribonuclease.
Ribonuclease activity is associated with subviral particles isolated from interferon-treated vesicular stomatitis virus-infected cells.
Virus Diseases
A Type III CRISPR Ancillary Ribonuclease Degrades Its Cyclic Oligoadenylate Activator.
Alteration of nuclear (2'-5')oligoriboadenylate synthetase and nuclease activities preceding replication of human immunodeficiency virus in H9 cells.
Dynamic changes in the activities of glucose-6-phosphate dehydrogenase, ribulose bisphosphate carboxylase and ribonuclease in tobacco leaves, leaf discs and mesophyll protoplasts in relation to TMV multiplication.
Expression of interferon-stimulated gene 20 in vascular endothelial cells.
RNA regulation of the antiviral protein 2'-5'-oligoadenylate synthetase.
Type III-A CRISPR-associated protein Csm6 degrades cyclic hexa-adenylate activator using both CARF and HEPN domains.
Virus infection and other factors affecting ribonuclease activity of plant leaves.
Visna
Detection of picornavirus sequences in nervous tissue of amyotrophic lateral sclerosis and control patients.
Vitamin A Deficiency
[Effect of increased doses of cobalt on ribonuclease, desoxyribonuclease and catalase in vitamin A deficiency]
Vitiligo
RNASET2 is required for ROS propagation during oxidative stress-mediated cell death.
Werner Syndrome
The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains.
Wilms Tumor
Deficient expression of mRNA for the putative inductive factor bone morphogenetic protein-7 in chemically initiated rat nephroblastomas.
Xeroderma Pigmentosum
DNA adducts of cis-diamminedichloroplatinum(II) and its trans isomer inhibit RNA polymerase II differentially in vivo.