Reference on EC 3.1.13.4 - poly(A)-specific ribonuclease and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Korner, C.G.; Wormington, M.; Muckenthaler, M.; Schneider, S.; Dehlin, E.; Wahle, E.
The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes
EMBO J.
17
5427-5437
1998
Bos taurus, Xenopus sp., Homo sapiens (O95453), Homo sapiens
Ren, Y.G.; Martinez, J.; Virtanen, A.
Identification of the active site of poly(A)-specific ribonuclease by site-directed mutagenesis and Fe(2+)-mediated cleavage
J. Biol. Chem.
277
5982-5987
2002
Homo sapiens
Uchida, N.; Hoshino, S.i.; Katada, T.
Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein
J. Biol. Chem.
279
1383-1391
2004
Homo sapiens (Q504Q3), Homo sapiens
Virtanen, A.; Martinez, J.; Ren, Y.G.
Purification of poly(A)-specific ribonuclease
Methods Enzymol.
342
303-309
2001
Bos taurus, Homo sapiens, Xenopus sp.
Gao, M.; Fritz, D.T.; Ford, L.P.; Wilusz, J.
Interaction between a poly(A)-specific ribonuclease and the 5' cap influences mRNA deadenylation rates in vitro
Mol. Cell
5
479-488
2000
Homo sapiens
Lai, W.S.; Kennington, E.A.; Blackshear, P.J.
Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease
Mol. Cell. Biol.
23
3798-3812
2003
Homo sapiens (O95453)
Wu, M.; Reuter, M.; Lilie, H.; Liu, Y.; Wahle, E.; Song, H.
Structural insight into poly(A) binding and catalytic mechanism of human PARN
EMBO J.
24
4082-4093
2005
Homo sapiens (O95453), Homo sapiens
Nilsson, P.; Virtanen, A.
Expression and purification of recombinant poly(A)-specific ribonuclease (PARN)
Int. J. Biol. Macromol.
39
1-3
2006
Homo sapiens
Seal, R.; Temperley, R.; Wilusz, J.; Lightowlers, R.N.; Chrzanowska-Lightowlers, Z.M.
Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability
Nucleic Acids Res.
33
376-387
2005
Homo sapiens
Zhang, A.; Liu, W.F.; Yan, Y.B.
Role of the RRM domain in the activity, structure and stability of poly(A)-specific ribonuclease
Arch. Biochem. Biophys.
461
255-262
2007
Homo sapiens
Liu, W.; Zhang, A.; He, G.; Yan, Y.
The R3H domain stabilizes poly(A)-specific ribonuclease by stabilizing the RRM domain
Biochem. Biophys. Res. Commun.
360
846-851
2007
Homo sapiens
Liu, W.F.; Zhang, A.; Cheng, Y.; Zhou, H.M.; Yan, Y.B.
Effect of magnesium ions on the thermal stability of human poly(A)-specific ribonuclease
FEBS Lett.
581
1047-1052
2007
Homo sapiens
Nilsson, P.; Henriksson, N.; Niedzwiecka, A.; Balatsos, N.A.; Kokkoris, K.; Eriksson, J.; Virtanen, A.
A multifunctional RNA recognition motif in poly(A)-specific ribonuclease with cap and poly(A) binding properties
J. Biol. Chem.
282
32902-32911
2007
Homo sapiens
Liu, W.F.; Zhang, A.; Cheng, Y.; Zhou, H.M.; Yan, Y.B.
Allosteric regulation of human poly(A)-specific ribonuclease by cap and potassium ions
Biochem. Biophys. Res. Commun.
379
341-345
2009
Homo sapiens
Monecke, T.; Schell, S.; Dickmanns, A.; Ficner, R.
Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode
J. Mol. Biol.
382
827-834
2008
Homo sapiens (O95453)
Balatsos, N.A.; Vlachakis, D.; Maragozidis, P.; Manta, S.; Anastasakis, D.; Kyritsis, A.; Vlassi, M.; Komiotis, D.; Stathopoulos, C.
Competitive inhibition of human poly(A)-specific ribonuclease (PARN) by synthetic fluoro-pyranosyl nucleosides
Biochemistry
48
6044-6051
2009
Homo sapiens (O95453), Homo sapiens
Balatsos, N.A.; Anastasakis, D.; Stathopoulos, C.
Inhibition of human poly(A)-specific ribonuclease (PARN) by purine nucleotides: kinetic analysis
J. Enzyme Inhib. Med. Chem.
24
516-523
2009
Homo sapiens
Niedzwiecka, A.; Lekka, M.; Nilsson, P.; Virtanen, A.
Global architecture of human poly(A)-specific ribonuclease by atomic force microscopy in liquid and dynamic light scattering
Biophys. Chem.
158
141-149
2011
Homo sapiens (Q96LI5), Homo sapiens
Wang, H.; Morita, M.; Yang, X.; Suzuki, T.; Yang, W.; Wang, J.; Ito, K.; Wang, Q.; Zhao, C.; Bartlam, M.; Yamamoto, T.; Rao, Z.
Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity
EMBO J.
29
2566-2576
2010
Homo sapiens
He, G.J.; Liu, W.F.; Yan, Y.B.
Dissimilar roles of the four conserved acidic residues in the thermal stability of poly(a)-specific ribonuclease
Int. J. Mol. Sci.
12
2901-2916
2011
Homo sapiens (O95453)
Henriksson, N.; Nilsson, P.; Wu, M.; Song, H.; Virtanen, A.
Recognition of adenosine residues by the active site of poly(A)-specific ribonuclease
J. Biol. Chem.
285
163-170
2010
Homo sapiens
Maragozidis, P.; Karangeli, M.; Labrou, M.; Dimoulou, G.; Papaspyrou, K.; Salataj, E.; Pournaras, S.; Matsouka, P.; Gourgoulianis, K.I.; Balatsos, N.A.
Alterations of deadenylase expression in acute leukemias: evidence for poly(A)-specific ribonuclease as a potential biomarker
Acta Haematol.
128
39-46
2012
Homo sapiens
He, G.J.; Zhang, A.; Liu, W.F.; Yan, Y.B.
Distinct roles of the R3H and RRM domains in poly(A)-specific ribonuclease structural integrity and catalysis
Biochim. Biophys. Acta
1834
1089-1098
2013
Homo sapiens (O95453)
He, G.J.; Yan, Y.B.
Self-association of poly(A)-specific ribonuclease (PARN) triggered by the R3H domain
Biochim. Biophys. Acta
1844
2077-2085
2014
Homo sapiens (O95453)
Yoda, M.; Cifuentes, D.; Izumi, N.; Sakaguchi, Y.; Suzuki, T.; Giraldez, A.J.; Tomari, Y.
Poly(A)-specific ribonuclease mediates 3-end trimming of Argonaute2-cleaved precursor microRNAs
Cell Rep.
5
715-726
2013
Homo sapiens
Vlachakis, D.; Pavlopoulou, A.; Tsiliki, G.; Komiotis, D.; Stathopoulos, C.; Balatsos, N.; Kossida, S.
An integrated in silico approach to design specific inhibitors targeting human poly(A)-specific ribonuclease
PLoS ONE
7
e51113
2012
Homo sapiens (O95453), Homo sapiens
He, G.; Yan, Y.
Contributions of the C-terminal domain to poly(A)-specific ribonuclease (PARN) stability and self-association
Biochem. Biophys. Rep.
18
100626
2019
Homo sapiens (O95453)
-
Zhang, L.; Yan, Y.
Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression
Biochim. Biophys. Acta
1853
522-534
2015
Homo sapiens (O95453), Homo sapiens
Niedzwiecka, A.; Nilsson, P.; Worch, R.; Stepinski, J.; Darzynkiewicz, E.; Virtanen, A.
Molecular recognition of mRNA 5' cap by 3' poly(A)-specific ribonuclease (PARN) differs from interactions known for other cap-binding proteins
Biochim. Biophys. Acta
1864
331-345
2016
Homo sapiens (O95453)
Jadhav, G.; Kaur, I.; Maryati, M.; Airhihen, B.; Fischer, P.; Winkler, G.
Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1
Bioorg. Med. Chem. Lett.
25
4219-4224
2015
Homo sapiens (O95453), Homo sapiens (Q9UIV1), Homo sapiens
Dhanraj, S.; Gunja, S.M.; Deveau, A.P.; Nissbeck, M.; Boonyawat, B.; Coombs, A.J.; Renieri, A.; Mucciolo, M.; Marozza, A.; Buoni, S.; Turner, L.; Li, H.; Jarrar, A.; Sabanayagam, M.; Kirby, M.; Shago, M.; Pinto, D.; Berman, J.N.; Scherer, S.W.; Virtanen, A.; Dror, Y.
Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)
J. Med. Genet.
52
738-748
2015
Homo sapiens (O95453), Homo sapiens
Maragozidis, P.; Papanastasi, E.; Scutelnic, D.; Totomi, A.; Kokkori, I.; Zarogiannis, S.G.; Kerenidi, T.; Gourgoulianis, K.I.; Balatsos, N.A.
Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer prognostic value and impact on gene expression
Mol. Cancer
14
187
2015
Homo sapiens (O95453), Homo sapiens
Moon, D.H.; Segal, M.; Boyraz, B.; Guinan, E.; Hofmann, I.; Cahan, P.; Tai, A.K.; Agarwal, S.
Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component
Nat. Genet.
47
1482-1488
2015
Homo sapiens (O95453), Homo sapiens
Anastasakis, D.; Skeparnias, I.; Shaukat, A.N.; Grafanaki, K.; Kanellou, A.; Taraviras, S.; Papachristou, D.J.; Papakyriakou, A.; Stathopoulos, C.
Mammalian PNLDC1 is a novel poly(A) specific exonuclease with discrete expression during early development
Nucleic Acids Res.
44
8908-8920
2016
Homo sapiens (Q8NA58), Homo sapiens, Mus musculus (B2RXZ1), Mus musculus
Ishikawa, H.; Yoshikawa, H.; Izumikawa, K.; Miura, Y.; Taoka, M.; Nobe, Y.; Yamauchi, Y.; Nakayama, H.; Simpson, R.J.; Isobe, T.; Takahashi, N.
Poly(A)-specific ribonuclease regulates the processing of small-subunit rRNAs in human cells
Nucleic Acids Res.
45
3437-3447
2017
Homo sapiens (O95453), Homo sapiens
Montellese, C.; Montel-Lehry, N.; Henras, A.K.; Kutay, U.; Gleizes, P.E.; ODonohue, M.F.
Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation
Nucleic Acids Res.
45
6822-6836
2017
Homo sapiens (O95453), Homo sapiens
Lee, D.; Park, D.; Park, J.; Kim, J.; Shin, C.
Poly(A)-specific ribonuclease sculpts the 3' ends of microRNAs
RNA
25
388-405
2019
Homo sapiens (O95453)
-
