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Information on EC 3.1.1.31 - 6-phosphogluconolactonase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC3.1.1.31

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The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
6-phosphogluconolactonase, 6pgl, phosphogluconolactonase, glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, g6pd-6pgl, 6-pgl, 6-phosphoglucono-gamma-lactonase, xoo2316, og1rf_11582, 6-phosphogluconolactonase 3, more

SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6-PGL
-
-
-
-
6-phospho-D-glucose-delta-lactone hydrolase
-
-
-
-
6-phosphoglucono-gamma-lactonase
-
-
-
-
6PGL
-
-
-
-
lactonase, phosphoglucono-
-
-
-
-
phosphogluconolactonase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of carboxylic ester
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
Entner-Doudoroff pathway I, formaldehyde oxidation I, heterolactic fermentation, pentose phosphate pathway (oxidative branch) I, superpathway of glycolysis and the Entner-Doudoroff pathway
SYSTEMATIC NAME
IUBMB Comments
6-phospho-D-glucono-1,5-lactone lactonohydrolase
-
CAS REGISTRY NUMBER
COMMENTARY hide
37278-45-8
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-5-oxo-2-tetrahydrofurancarboxylic acid + H2O
L-alpha-hydroxyglutaric acid
show the reaction diagram
-
Substrates: -
Products: -
?
6-phospho-D-glucono-1,5-lactone + H2O
6-phospho-D-gluconate
show the reaction diagram
D-glucono-delta-lactone + H2O
?
show the reaction diagram
-
Substrates: -
Products: -
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
6-phospho-D-glucono-1,5-lactone + H2O
6-phospho-D-gluconate
show the reaction diagram
Substrates: -
Products: -
?
top print hide Go to Organism Search
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
top print hide Go to Localization Search
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Highest Expressing Human Cell Lines
Cell Line Links Gene Links
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A077JSQ0_PSEAI
238
0
25615
TrEMBL
-
A0A0C7CS03_PSEAI
238
0
25571
TrEMBL
Secretory Pathway (Reliability: 1)
A0A0F6RRD9_PSEAI
238
0
25614
TrEMBL
-
A0A367MDX9_PSEAI
238
0
25453
TrEMBL
-
A0A6A9JWB9_PSEAI
238
0
25621
TrEMBL
other Location (Reliability: 1)
A0A8G3F1X0_PSEAI
238
0
25599
TrEMBL
-
A0ABD7K3M1_PSEAI
238
0
25600
TrEMBL
other Location (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
40000
-
SDS-PAGE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
His-Trap nickel affinity column chromatography and Superdex 75 gel filtration
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as a His fusion protein in Escherichia coli BL21(DE3) cells
-
pgl is a member of the hex regulon
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hager, P.W.; Calfee, M.W.; Phibbs, P.V.
The Pseudomonas aeruginosa devB/SOL homolog, pgl, is a member of the hex regulon and encodes 6-phosphogluconolactonase
J. Bacteriol.
182
3934-3941
2000
Pseudomonas aeruginosa (Q9X2N2), Pseudomonas aeruginosa
Manually annotated by BRENDA team
Tarighi, S.; Wei, Q.; Camara, M.; Williams, P.; Fletcher, M.P.; Kajander, T.; Cornelis, P.
The PA4204 gene encodes a periplasmic gluconolactonase (PpgL) which is important for fitness of Pseudomonas aeruginosa
Microbiology
154
2979-2990
2008
Pseudomonas aeruginosa
Manually annotated by BRENDA team