Reference on EC 2.8.3.5 - 3-oxoacid CoA-transferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zammit, V.A.; Beis, A.; Newsholme, E.A.
The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver
FEBS Lett.
103
212-215
1979
Gallus gallus, Clupea harengus, Columba livia, Oryctolagus cuniculus, Dicentrarchus labrax, Lacerta viridis, Mus musculus, Oncorhynchus mykiss, Pleuronectes platessa, Raja clavata, Rattus norvegicus, Scomber scombrus, Scyliorhinus canicula
Hersh, L.B.; Jencks, W.P.
Coenzyme A transferase. Kinetics and exchange reactions
J. Biol. Chem.
242
3468-3480
1967
Sus scrofa
-
Edwards, M.R.; Singh, M.; Tubbs, P.K.
A simple purification of acetoacetate-succinate CoA-transferase using substrate elution chromatography
FEBS Lett.
37
155-158
1973
Sus scrofa
White, H.; Jencks, W.P.
Properties of succinyl-CoA:3-ketoacid coenzyme A transferase
J. Biol. Chem.
251
1708-1711
1976
Sus scrofa
Kindman, L.A.; Jencks, W.P.
Modification and inactivation of CoA transferase by 2-nitro-5-(thiocyanato)benzoate
Biochemistry
20
5183-5187
1981
Sus scrofa
Lin, T.; Bridger, W.A.
Sequence of a cDNA clone encoding pig heart mitochondrial CoA transferase
J. Biol. Chem.
267
975-978
1992
Sus scrofa
Fenselau, A.; Wallis, K.
Comparative studies on 3-oxo acid coenzyme A transferase from various rat tissues
Biochem. J.
142
619-627
1974
Rattus norvegicus
Russell, J.J.; Patel, M.S.
Purification and properties of succinyl-CoA:3-oxo-acid CoA-transferase from rat brain
J. Neurochem.
38
1446-1452
1982
Rattus norvegicus
Fenselau, A.; Wallis, K.
Ketone body usage by mammals. Acetoacetate substrate inhibition of CoA transferase from various rat tissues
Life Sci.
15
811-818
1974
Rattus norvegicus
Fenselau, A.; Wallis, K.
Ping-pong chromatography. A novel purification of CoA-transferase
Biochem. Biophys. Res. Commun.
62
350-356
1975
Rattus norvegicus
Hanson, P.J.; Carrington, J.M.
Activity of 3-oxo acid CoA-transferase, D-3-hydroxybutyrate dehydrogenase, hexokinase and carnitine palmitoyltransferase in the stomach and small and large intestine of the rat
Biochem. J.
200
349-355
1981
Rattus norvegicus
Haney, P.M.; Bolinger, L.; Raefsky, C.; Patel, M.S.
Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells
Biochem. J.
224
67-74
1984
Mus musculus, Rattus norvegicus
Fenselau, A.; Wallis, K.
Substrate specificity and mechanism of action of acetoacetate coenzyme A transferase from rat heart
Biochemistry
13
3884-3889
1974
Rattus norvegicus
Sharp, J.A.; Edwards, M.R.
Purification and properties of succinyl-coenzyme A-3-oxo acid coenzyme A-transferase from sheep kidney
Biochem. J.
173
759-765
1978
Ovis aries, Sus scrofa
Sharp, J.A.; Edwards, M.R.
Initial-velocity kinetics of succinoyl-coenzyme A-3-oxo acid coenzyme A-transferase from sheep kidney
Biochem. J.
213
179-185
1983
Ovis aries
Berry, G.T.; Fukao, T.; Mitchell, G.A.; Mazur, A.; Ciafre, M.; Gibson, J.; Kondo, N.; Palmieri, M.J.
Neonatal hypoglycaemia in severe succinyl-CoA: 3-oxoacid CoA-transferase deficiency
J. Inherit. Metab. Dis.
24
587-595
2001
Homo sapiens
Corthesy-Theulaz, I.E.; Bergonzelli, G.E.; Henry, H.; Bachmann, D.; Schorderet, D.F.; Blum, A.L.; Ornston, L.N.
Cloning and characterization of Helicobacter pylori succinyl CoA:acetoacetate CoA-transferase, a novel prokaryotic member of the CoA-transferase family
J. Biol. Chem.
272
25659-25667
1997
Helicobacter pylori, Helicobacter pylori 69A
Kassovska-Bratinova, S.; Fukao, T.; Song, X.Q.; Duncan, A.M.V.; Chen, H.S.; Robert, M.F.; Perez-Cerda, C.; Ugarte, M.; Chartrand, C.; et al.
Succinyl CoA:3-oxoacid CoA transferase (SCOT): human cDNA cloning, human chromosomal mapping to 5p13, and mutation detection in a SCOT-deficient patient
Am. J. Hum. Genet.
59
519-528
1996
Homo sapiens
Koga, M.; Tanaka, H.; Yomogida, K.; Nozaki, M.; Tsuchida, J.; Ohta, H.; Nakamura, Y.; Masai, K.; Yoshimura, Y.; Yamanaka, M.; Iguchi, N.; Nojima, H.; Matsumiya, K.; Okuyama, A.; Nishimune, Y.
Isolation and characterization of a haploid germ cell-specific novel complementary deoxyribonucleic acid; testis-specific homologue of succinyl CoA:3-Oxo acid CoA transferase
Biol. Reprod.
63
1601-1609
2000
Mus musculus, Mus musculus (Q9JJN4)
Lloyd, A.J.; Shoolingin-Jordan, P.M.
dimeric pig heart succinate-coenzyme A transferase zses only one subunit to support catalysis
Biochemistry
40
2455-2467
2001
Sus scrofa
Marcondes, S.; Turko, I.V.; Murad, F.
Nitration of succinyl-CoA:3-oxoacid CoA-transferase in rats after endotoxin administration
Proc. Natl. Acad. Sci. USA
98
7146-7151
2001
Rattus norvegicus
Rochet, J.C.; Bridger, W.A.
Identification of glutamate 344 as the catalytic residue in the active site of pig heart CoA transferase
Protein Sci.
3
975-981
1994
Sus scrofa
Rochet, J.C.; Brownie, E.R.; Oikawa, K.; Hicks, L.D.; Fraser, M.E.; James, M.N.; Kay, C.M.; Bridger, W.A.; Wolodko, W.T.
Pig heart CoA transferase exists as two oligomeric forms separated by a large kinetic barrier
Biochemistry
39
11291-11302
2000
Sus scrofa
Rochet, J.C.; Oikawa, K.; Hicks, L.D.; Kay, C.M.; Bridger, W.A.; Wolodko, W.T.
Productive interactions between the two domains of pig heart CoA transferase during folding and assembly
Biochemistry
36
8807-8820
1997
Sus scrofa
Song, X.Q.; Fukao, T.; Mitchell, G.A.; Kassovska-Bratinova, S.; Ugarte, M.; Wanders, R.J.; Hirayama, K.; Shintaku, H.; Churchill, P.; Watanabe, H.; Orii, T.; Kondo, N.
Succinyl-CoA:3-ketoacid coenzyme A transferase (SCOT): development of an antibody to human SCOT and diagnostic use in hereditary SCOT deficiency
Biochim. Biophys. Acta
1360
151-156
1997
Homo sapiens
Song, X.Q.; Fukao, T.; Watanabe, H.; Shintaku, H.; Hirayama, K.; Kassovska-Bratinova, S.; Kondo, N.; Mitchell, G.A.
Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency: two pathogenic mutations, V133E and C456F, in Japanese siblings
Hum. Mutat.
12
83-88
1998
Homo sapiens
Tanaka, H.; Kohroki, J.; Iguchi, N.; Onishi, M.; Nishimune, Y.
Cloning and characterization of a human orthologue of testis-specific succinyl CoA: 3-oxo acid CoA transferase (Scot-t) cDNA
Mol. Hum. Reprod.
8
16-23
2002
Homo sapiens (Q9BYC2), Homo sapiens
Turko, I.V.; Marcondes, S.; Murad, F.
Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase
Am. J. Physiol.
281
H2289-H2294
2001
Rattus norvegicus
Whitty, A.; Fierke, C.A.; Jencks, W.P.
Role of binding energy with coenzyme A in catalysis by 3-oxoacid coenzyme A transferase
Biochemistry
34
11678-11689
1995
Sus scrofa
Coros, A.M.; Swenson, L.; Wolodko, W.T.; Fraser, M.E.
Structure of the CoA transferase from pig heart to 1.7 A resolution
ACTA CRYSTALLOGR. SECT. D
60
1717-1725
2004
Sus scrofa
El Midaoui, A.; Chiasson, J.L.; Tancrede, G.; Nadeau, A.
Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats
Am. J. Physiol.
288
E748-752
2005
Rattus norvegicus
Ohnuki, M.; Takahashi, N.; Yamasaki, M.; Fukui, T.
Different localization in rat brain of the novel cytosolic ketone body-utilizing enzyme, acetoacetyl-CoA synthetase, as compared to succinyl-CoA:3-oxoacid CoA-transferase
Biochim. Biophys. Acta
1729
147-153
2005
Rattus norvegicus
Fukao, T.; Shintaku, H.; Kusubae, R.; Zhang, G.X.; Nakamura, K.; Kondo, M.; Kondo, N.
Patients homozygous for the T435N mutation of succinyl-CoA:3-ketoacid CoA Transferase (SCOT) do not show permanent ketosis
Pediatr. Res.
56
858-863
2004
Homo sapiens
Tammam, S.D.; Rochet, J.C.; Fraser, M.E.
Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A
Biochemistry
46
10852-10863
2007
Sus scrofa, Sus scrofa (Q29551)
Yamada, K.; Fukao, T.; Zhang, G.; Sakurai, S.; Ruiter, J.P.; Wanders, R.J.; Kondo, N.
Single-base substitution at the last nucleotide of exon 6 (c.671G>A), resulting in the skipping of exon 6, and exons 6 and 7 in human succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene
Mol. Genet. Metab.
90
291-297
2007
Homo sapiens
Stols, L.; Zhou, M.; Eschenfeldt, W.H.; Millard, C.S.; Abdullah, J.; Collart, F.R.; Kim, Y.; Donnelly, M.I.
New vectors for co-expression of proteins: structure of Bacillus subtilis ScoAB obtained by high-throughput protocols
Protein Expr. Purif.
53
396-403
2007
Bacillus subtilis
Rebrin, I.; Bregere, C.; Kamzalov, S.; Gallaher, T.K.; Sohal, R.S.
Nitration of tryptophan 372 in succinyl-CoA:3-ketoacid CoA transferase during aging in rat heart mitochondria
Biochemistry
46
10130-10144
2007
Rattus norvegicus
Fukao, T.; Kursula, P.; Owen, E.P.; Kondo, N.
Identification and characterization of a temperature-sensitive R268H mutation in the human succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene
Mol. Genet. Metab.
92
216-221
2007
Homo sapiens
Orii, K.E.; Fukao, T.; Song, X.Q.; Mitchell, G.A.; Kondo, N.
Liver-specific silencing of the human gene encoding succinyl-CoA: 3-ketoacid CoA transferase
Tohoku J. Exp. Med.
215
227-236
2008
Homo sapiens (P55809), Homo sapiens
MacDonald, M.J.; Longacre, M.J.; Langberg, E.C.; Tibell, A.; Kendrick, M.A.; Fukao, T.; Ostenson, C.G.
Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
Diabetologia
52
1087-1091
2009
Homo sapiens
Bregere, C.; Rebrin, I.; Gallaher, T.K.; Sohal, R.S.
Effects of age and calorie restriction on tryptophan nitration, protein content, and activity of succinyl-CoA:3-ketoacid CoA transferase in rat kidney mitochondria
Free Radic. Biol. Med.
48
609-618
2009
Rattus norvegicus, Rattus norvegicus (B2GV06)
Skinner, R.; Trujillo, A.; Ma, X.; Beierle, E.
Ketone bodies inhibit the viability of human neuroblastoma cells
J. Pediatr. Surg.
44
212-216
2009
Homo sapiens
Bregere, C.; Rebrin, I.; Sohal, R.S.
Detection and characterization of in vivo nitration and oxidation of tryptophan residues in proteins
Methods Enzymol.
441
339-349
2008
Rattus norvegicus
Coker, S.F.; Lloyd, A.J.; Mitchell, E.; Lewis, G.R.; Coker, A.R.; Shoolingin-Jordan, P.M.
The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase
Acta Crystallogr. Sect. D
66
797-805
2010
Sus scrofa (Q29551), Sus scrofa
Hasan, N.M.; Longacre, M.J.; Seed Ahmed, M.; Kendrick, M.A.; Gu, H.; Ostenson, C.G.; Fukao, T.; MacDonald, M.J.
Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells
Arch. Biochem. Biophys.
499
62-68
2010
Rattus norvegicus (B2GV06)
Fraser, M.E.; Hayakawa, K.; Brown, W.D.
Catalytic role of the conformational change in succinyl-CoA:3-oxoacid CoA transferase on binding CoA
Biochemistry
49
10319-10328
2010
Sus scrofa (Q29551), Sus scrofa
Fukao, T.; Sass, J.O.; Kursula, P.; Thimm, E.; Wendel, U.; Ficicioglu, C.; Monastiri, K.; Guffon, N.; Bari?, I.; Zabot, M.T.; Kondo, N.
Clinical and molecular characterization of five patients with succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency
Biochim. Biophys. Acta
1812
619-624
2011
Homo sapiens
Zhang, M.; Xu, H.Y.; Wang, Y.C.; Shi, Z.B.; Zhang, N.N.
Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster
Acta Crystallogr. Sect. F
69
1089-1093
2013
Drosophila melanogaster (Q9W058), Drosophila melanogaster
Cong, W.; Ma, W.; Zhao, T.; Zhu, Z.; Wang, Y.; Tan, Y.; Li, X.; Jin, L.; Cai, L.
Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374)
Am. J. Physiol. Endocrinol. Metab.
304
E826-E835
2013
Mus musculus (Q9D0K2)
Shafqat, N.; Kavanagh, K.L.; Sass, J.O.; Christensen, E.; Fukao, T.; Lee, W.H.; Oppermann, U.; Yue, W.W.
A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency
J. Inherit. Metab. Dis.
36
983-987
2013
Homo sapiens (P55809), Homo sapiens
Chutoam, P.; Charoensawan, V.; Wongtrakoongate, P.; Kum-Arth, A.; Buphamalai, P.; Tungpradabkul, S.
RpoS and oxidative stress conditions regulate succinyl-CoA: 3-ketoacid-coenzyme A transferase (SCOT) expression in Burkholderia pseudomallei
Microbiol. Immunol.
57
605-615
2013
Burkholderia pseudomallei (Q63TL3), Burkholderia pseudomallei, Burkholderia pseudomallei K96243 (Q63TL3)
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