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Information on EC 2.7.7.74 - 1L-myo-inositol 1-phosphate cytidylyltransferase

for references in articles please use BRENDA:EC2.7.7.74
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IUBMB Comments
In many organisms this activity is catalysed by a bifunctional enzyme. The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 (CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase) is absolutely specific for CTP and 1L-myo-inositol 1-phosphate. The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate, a widespread organic solute in microorganisms adapted to hot environments.
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The enzyme appears in viruses and cellular organisms
Synonyms
CDP-inositol:inositol-1-phosphate transferase, CTP:inositol-1-phosphate cytidylyltransferase, ICPT, IPCT, Tmari_1425, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CTP + 1L-myo-inositol 1-phosphate = diphosphate + CDP-1L-myo-inositol
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