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Disease on EC 2.7.7.49 - RNA-directed DNA polymerase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abnormalities, Multiple
Dyskeratosis congenita: a disorder of defective telomere maintenance?
Dyskeratosis congenita: molecular insights into telomerase function, ageing and cancer.
Abortion, Habitual
Implications of telomeres and telomerase in endometrial pathology.
Abortion, Spontaneous
Expression of telomerase activity in human chorion.
Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies.
Acidosis
High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment.
Lactic acidosis and hyperlactatemia associated with lamivudine accumulation and sepsis in a kidney transplant recipient-a case report and review of the literature.
Renal tubular acidosis and hypophosphataemia after treatment with nucleoside reverse transcriptase inhibitors.
Validation of the Accutrend((R)) lactate meter for hyperlactatemia screening during antiretroviral therapy in a resource-poor setting.
Acidosis, Lactic
A case of lactic acidosis caused by stavudine in an AIDS patient.
A high incidence of lactic acidosis and symptomatic hyperlactatemia in women receiving highly active antiretroviral therapy in Soweto, South Africa.
A high incidence of nucleoside reverse transcriptase inhibitor (NRTI)-induced lactic acidosis in HIV-infected patients in a South African context.
Alteration of cytochrome oxidase subunit I labeling is associated with severe mitochondriopathy in NRTI-related hepatotoxicity in HIV patients.
Clinical features and risk factors of lactic acidosis following long-term antiretroviral therapy: 4 fatal cases.
Elevated lactate levels in hospitalized persons with HIV infection.
Extensive investigations of mitochondrial DNA genome in treated HIV-infected subjects: beyond mitochondrial DNA depletion.
Fatal Tenofovir-Associateacd Lactic Acidosis: A Case Report.
Hepatic steatosis and lactic acidosis caused by stavudine in an HIV-infected patient.
High doses of riboflavin and thiamine may help in secondary prevention of hyperlactatemia.
HIV-associated neuromuscular weakness syndrome.
Human immunodeficiency virus infection with human granulocytic ehrlichiosis complicated by symptomatic lactic acidosis.
Hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral therapy.
Hyperlactataemia in HIV-infected patients: the role of NRTI-treatment.
Lactic acidosis and anti-retroviral drugs.
Lactic acidosis associated with nucleoside reverse transcriptase inhibitors.
Lactic acidosis associated with severe neuromuscular weakness and stavudine therapy.
Lactic acidosis in an HIV-infected patient receiving highly active antiretroviral therapy.
Lactic acidosis in HIV-exposed infants with perinatal exposure to antiretroviral therapy.
Linezolid use associated with lactic acidosis.
Managing issues related to antiretroviral therapy.
Metabolic complications and treatment of perinatally HIV-infected children and adolescents.
Mild to moderate symptoms do not correlate with lactate levels in HIV-positive patients on nucleoside reverse transcriptase inhibitors.
Mutations of mtDNA polymerase-? and hyperlactataemia in the HIV-infected Zulu population of South Africa.
Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment.
Prognostic factors in lactic acidosis syndrome caused by nucleoside reverse transcriptase inhibitors: report of eight cases and review of the literature.
Real-World Experience With Higher-Than-Recommended Doses of Lamivudine in Patients With Varying Degrees of Renal Impairment.
Recurrent Anion Gap Metabolic Acidosis.
Riboflavin treatment of antiretroviral induced lactic acidosis and hepatic steatosis.
Risk factors for lactic acidosis in HIV-infected patients treated with nucleoside reverse-transcriptase inhibitors: a case-control study.
Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.
Severe nucleoside-associated lactic acidosis in human immunodeficiency virus-infected patients: report of 12 cases and review of the literature.
The nephrotoxic effects of HAART.
The role of nucleoside reverse transcriptase inhibitors usage in the incidence of hyperlactatemia and lactic acidosis in HIV/AIDS patients.
Treatment of nucleoside reverse transcriptase inhibitor-induced lactic acidosis.
Type B Lactic Acidosis Associated With Venlafaxine Overdose.
Validation of A Point-of-Care Lactate Device For Screening At-Risk Adults Receiving Combination Antiretroviral Therapy In Botswana.
[Lactic acidosis type B. A life-threatening adverse effect of antiretroviral therapy]
[Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors]
Acidosis, Renal Tubular
Renal tubular acidosis and hypophosphataemia after treatment with nucleoside reverse transcriptase inhibitors.
Acquired Immunodeficiency Syndrome
'Infectious web'.
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase.
A brief overview of mechanisms of mitochondrial toxicity from NRTIs.
A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.
A nanoparticle-encapsulated non-nucleoside reverse-transcriptase inhibitor with enhanced anti-HIV-1 activity and prolonged circulation time in plasma.
A new generation of peptide-based inhibitors targeting HIV-1 reverse transcriptase conformational flexibility.
A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.
A novel vaginal drug delivery system: anti-HIV bioadhesive film containing abacavir.
A transient kinetic approach to investigate nucleoside inhibitors of mitochondrial DNA polymerase gamma.
Accelerated replicative senescence of the peripheral immune system induced by HIV infection.
Activation of c-Jun N-terminal kinase mediates gp120IIIB- and nucleoside analogue-induced sensory neuron toxicity.
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy.
Analysis of human immunodeficiency virus type 1 drug resistance in children receiving nucleoside analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir (Pediatric AIDS Clinical Trials Group 377).
Boosted protease inhibitor monotherapy in HIV-infected adults: outputs from a pan-European expert panel meeting.
Cardiomyopathy, nucleoside reverse transcriptase inhibitors and mitochondria are linked through AIDS and its therapy.
Characteristics of a group of nonnucleoside reverse transcriptase inhibitors with structural diversity and potent anti-human immunodeficiency virus activity.
Characterization of New DNA Aptamers for Anti-HIV-1 Reverse Transcriptase.
Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions.
Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team.
Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV.
Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance.
Covalent coupling of nucleosides to low density lipoprotein (LDL) generates macrophage specific (drug)-carriers.
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor.
Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: a new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains.
Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
Designed multiple ligands: an emerging anti-HIV drug discovery paradigm.
Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine.
DNA polymerases versus HIV reverse transcriptase in AIDS therapy.
Efavirenz binding to HIV-1 reverse transcriptase monomers and dimers.
Effect of a bound non-nucleoside RT inhibitor on the dynamics of wild-type and mutant HIV-1 reverse transcriptase.
Electronic transduction of HIV-1 drug resistance in AIDS patients.
Evaluation of viral resistance to reverse transcriptase inhibitors (RTI) in HIV-1-infected patients before and after 6 months of single or double antiretroviral therapy.
Expression of the human immunodeficiency virus gag gene in insect cells.
Fidelity of HIV-1 reverse transcriptase.
Further characterization of sulfated homopolysaccharides as anti-HIV agents.
Genetic variants in telomerase-associated protein 1 are associated with telomere damage in PAH-exposed workers.
Genotype and phenotype patterns of drug-resistant HIV-1 subtype B' (Thai B) isolated from patients failing antiretroviral therapy in China.
High incidence of herpes zoster in patients with AIDS soon after therapy with protease inhibitors.
High Incidence of Zidovudine Induced Anaemia in HIV Infected Patients in Southern Odisha.
High prevalence of genotypic and phenotypic HIV-1 drug-resistant strains among patients receiving antiretroviral therapy in Abidjan, Côte d'Ivoire.
HIV reverse transcriptase inhibitors of natural origin.
HIV reverse transcriptase structure-function relationships.
HIV-1 reverse transcriptase codon 215 mutation in plasma RNA: immunologic and virologic responses to zidovudine. The AIDS Clinical Trials Group Study 175 Virology Team.
HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir.
HIV-1 RNA, CD4 cell count and the risk of progression to AIDS and death during treatment with HIV-1 reverse transcriptase inhibitors.
HIV-1-resistant strains during 8-week on 8-week off intermittent therapy and their effect on CD4+ T-cell counts and antiviral response.
HIV-related morbidity and mortality in patients starting protease inhibitors in very advanced HIV disease (CD4 count of < 50 cells/microL): an analysis of 338 clinical events from a randomized clinical trial.
HTLV-III gag protein is processed in yeast cells by the virus pol-protease.
Identification of the metabolites of the HIV-1 reverse transcriptase inhibitor delavirdine in monkeys.
Impact of Antiretroviral Drugs on Fracture Risk in HIV-Infected Individuals: A Case-Control Study Nested Within the French Hospital Database on HIV (FHDH-ANRS CO4).
Impact of indinavir on the quality of life in patients with advanced HIV infection treated with zidovudine and lamivudine.
Impaired CD4+ T-Cell Restoration in the Small Versus Large Intestine of HIV-1-Positive South Africans Receiving Combination Antiretroviral Therapy.
Improved survival in rhesus macaques immunized with modified vaccinia virus Ankara recombinants expressing simian immunodeficiency virus envelope correlates with reduction in memory CD4+ T-cell loss and higher titers of neutralizing antibody.
In utero nucleoside reverse transcriptase inhibitor exposure and cancer in HIV-uninfected children: an update from the pediatric AIDS clinical trials group 219 and 219C cohorts.
In vitro interaction of nucleoside reverse transcriptase inhibitor, didanosine with calf-thymus DNA: Insights from spectroscopic studies.
In vivo comparison of zidovudine resistance mutations in blood and CSF of HIV-1-infected patients.
Inhibition of human immunodeficiency virus type 1 replication in vitro by the bisheteroarylpiperazine atevirdine (U-87201E) in combination with zidovudine or didanosine.
Inhibition of human immunodeficiency virus type-1 reverse transcriptase by a novel peptide derived from the viral integrase.
Intrapatient variability of efavirenz concentrations as a predictor of virologic response to antiretroviral therapy.
Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.
Lack of evidence of mitochondrial dysfunction in the offspring of HIV-infected women. Retrospective review of perinatal exposure to antiretroviral drugs in the Perinatal AIDS Collaborative Transmission Study.
Long-term probability of detecting drug-resistant HIV in treatment-naive patients initiating combination antiretroviral therapy.
Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat.
Mechanism of inhibition of the human immunodeficiency virus type 1 reverse transcriptase by d4TTP: an equivalent incorporation efficiency relative to the natural substrate dTTP.
Metabolism of the HIV-1 reverse transcriptase inhibitor delavirdine in mice.
Mitochondrial DNA replication, nucleoside reverse-transcriptase inhibitors, and AIDS cardiomyopathy.
Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: experimental clarifications and persistent clinical questions.
Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective.
Molecular dynamics model of unliganded HIV-1 reverse transcriptase.
Molecular dynamics of HIV-1 reverse transcriptase indicates increased flexibility upon DNA binding.
Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate.
Mutagenicity and pausing of HIV reverse transcriptase during HIV plus-strand DNA synthesis.
Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV-1 Infection.
Newer aminopyrimidinimino isatin analogues as non-nucleoside HIV-1 reverse transcriptase inhibitors for HIV and other opportunistic infections of AIDS: design, synthesis and biological evaluation.
Non-nucleoside inhibitors of HIV reverse transcriptase: screening successes--clinical failures.
Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability.
Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide.
Nucleoside reverse transcriptase inhibitors, mitochondrial DNA and AIDS therapy.
Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance.
Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations.
Peptide and non-peptide HIV fusion inhibitors.
Peptide inhibition of HIV-1: current status and future potential.
Perspectives for the chemotherapy of AIDS.
Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure.
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases.
Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjects.
Pyranocoumarins from tropical species of the genus Calophyllum: a chemotaxonomic study of extracts in the National Cancer Institute collection.
Recent discoveries in HIV-1 reverse transcriptase inhibitors.
Schwann cell mitochondrial alterations in peripheral nerves of rabbits treated with 2',3'-dideoxycytidine.
Selective and synergistic inhibition of human immunodeficiency virus type 1 reverse transcriptase by a non-nucleoside inhibitor, MKC-442.
Solution characterization of [methyl-(13)C]methionine HIV-1 reverse transcriptase by NMR spectroscopy.
Spindle cells from Acquired Immune Deficiency Syndrome (AIDS)-associated Kaposi's sarcoma (KS) lesions express telomerase activity directly relating to the RNA levels of fibroblast growth factor (FGF)-2.
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
Structure-based design and engineering of a nontoxic recombinant pokeweed antiviral protein with potent anti-human immunodeficiency virus activity.
Study on the interaction between HIV reverse transcriptase and its non-nucleoside inhibitor nevirapine by capillary electrophoresis.
Subtype polymorphisms among HIV-1 protease variants confer altered flap conformations and flexibility.
Targeted transgenic overexpression of mitochondrial thymidine kinase (TK2) alters mitochondrial DNA (mtDNA) and mitochondrial polypeptide abundance: transgenic TK2, mtDNA, and antiretrovirals.
Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategies.
Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy.
Telomere-regulating genes and the telomere interactome in familial cancers.
The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets.
The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic.
The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.
The HIV RNA Levels of Plasma and Ocular Fluids in AIDS Patients with Ophthalmic Infections.
The HIV-1 reverse transcription (RT) process as target for RT inhibitors.
The observed inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate for HIV-1 reverse transcriptase depends on the length of the poly(rA) region of the template.
The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy.
Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site.
Transgenic expression of the deoxynucleotide carrier causes mitochondrial damage that is enhanced by NRTIs for AIDS.
Trapping of a catalytic HIV reverse transcriptase*template:primer complex through a disulfide bond.
Viral load outcome of non-nucleoside reverse transcriptase inhibitor regimens for 2203 mainly antiretroviral-experienced patients.
Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection.
[Impacts of HIV-1 resistance mutations associated with nucleoside reverse transcriptase inhibitors on viral fitness].
[Inhibitors of HIV-1 reverse transcriptase and protease as chemotherapeutics for AIDS]
[Research on the selective kinetics of HIV-1 nucleoside reverse transcriptase inhibitor drug resistance-associated mutations among 4 AIDS patients receiving highly active antiretroviral therapy]
Acromegaly
Expression of growth hormone receptor isoform exon-3-excluding and exon-3-retaining messenger RNAs in peripheral lymphocytes from normal and acromegalic subjects.
Prognostic implications of telomerase expression in pituitary adenomas.
Acute Coronary Syndrome
Prognostic value of telomere length in acute coronary syndrome.
Telomerase Activation to Reverse Immunosenescence in Elderly Patients With Acute Coronary Syndrome: Protocol for a Randomized Pilot Trial.
The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome.
The role of the terc-63g>a and tert-1327c>t telomerase polymorphisms in the study of men with acute coronary syndrome.
Acute Kidney Injury
Telomerase, Autophagy and Acute Kidney Injury.
Telomeres and telomerase in renal health.
The nephrotoxic effects of HAART.
Acute-On-Chronic Liver Failure
Liver Transplantation for Decompensated Cirrhosis Secondary to Telomerase Reverse Transcriptase (TERT) Mutation.
Adenocarcinoma
A Combination of ?-Tocotrienol and Ferulic Acid Synergistically Inhibits Telomerase Activity in DLD-1 Human Colorectal Adenocarcinoma Cells.
A simple two-gene prognostic model for adenocarcinoma of the lung.
Allelotype and loss of heterozygosity around the L-myc gene locus in primary lung cancers.
Alternative lengthening of telomeres is induced by telomerase inhibitors in Barrett's esophageal cells.
Androgens stimulate telomerase expression, activity and phosphorylation in ovarian adenocarcinoma cells.
Antiproliferative effects of the major tea polyphenol, (-)-epigallocatechin gallate and retinoic acid in cervical adenocarcinoma.
Aurora kinase expression in colorectal adenocarcinoma: correlations with clinicopathological features, p16 expression, and telomerase activity.
AZT as a telomerase inhibitor.
Cancer-associated stromal fibroblasts promote pancreatic tumor progression.
Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.
Cellular proliferative and telomerase activity in canine mammary gland tumors.
Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis.
Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy.
Correspondence re: Seki et al., Diagnosis of pancreatic adenocarcinoma by detection of human telomerase reverse transcriptase messenger RNA in pancreatic juice with sample qualification. Clin. Cancer Res., 7: 1976-1981, 2001.
Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors.
Decreasing telomerase activity of adenocarcinoma cancer cell line (AGS) is associated with different concentrations of sodium selenite and cadmium chloride and selenium l methionine.
Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization.
Detection of circulating prostate derived cells in patients with prostate adenocarcinoma is an independent risk factor for tumor recurrence.
Detection of hTERT mRNA in colonic brush specimens as an adjunct to cytopathologic diagnosis of colonic adenocarcinoma.
Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer.
Determination of qualitative telomerase activity as an adjunct to the diagnosis of pancreatic adenocarcinoma by EUS-guided fine-needle aspiration.
Diagnosis of pancreatic adenocarcinoma by detection of human telomerase reverse transcriptase messenger RNA in pancreatic juice with sample qualification.
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours.
Down-regulation of KAI1 messenger RNA expression is not associated with loss of heterozygosity of the KAI1 gene region in lung adenocarcinoma.
Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol.
Dual mechanisms for telomerase inhibition in DLD-1 human colorectal adenocarcinoma cells by polyunsaturated fatty acids.
Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells.
Effects of low concentrations of benzene on human lung cells in vitro.
Effects of various agents on DNA fragmentation and telomerase enzyme activities in adenocarcinoma cell lines.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
Elevated level of microRNA-21 in the serum of patients with colorectal cancer.
Evaluation of telomerase in the development and progression of colon cancer.
Evidence for Enhanced Telomerase Activity in Barrett's Esophagus with Dysplasia and Adenocarcinoma.
Expression of telomerase & its significance in the diagnosis of pancreatic cancer.
Expression of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in gastric adenocarcinomas.
Expression of telomerase genes correlates with telomerase activity in human colorectal carcinogenesis.
Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells.
Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas.
Functional Loss of ATRX and TERC Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells.
Genetic and epigenetic changes in stomach cancer.
Genetic Polymorphism, Telomere Biology and Non-Small Lung Cancer Risk.
GOLPH3 Promotes Cancer Growth by Interacting With STIP1 and Regulating Telomerase Activity in Pancreatic Ductal Adenocarcinoma.
Growth arrest, apoptosis, and telomere shortening of Barrett's-associated adenocarcinoma cells by a telomerase inhibitor.
Htert gene expression levels and telomerase activity in drug resistant mcf-7 cells.
HTERT mRNA partially regulates telomerase activity in gastric adenocarcinoma and adjacent normal gastric mucosa.
Human telomerase RNA as endogenous control in endometrial tissue.
Immunohistochemical detection of human telomerase reverse transcriptase (hTERT), topoisomerase IIalpha expression, and apoptosis in endometrial adenocarcinoma and atypical hyperplasia.
Immunohistochemical detection of telomerase reverse transcriptase in colorectal adenocarcinoma and benign colonic mucosa.
Immunohistochemical expression of ubiquitin and telomerase in cervical cancer.
In situ hybridization for the detection of telomerase RNA in the progression from Barrett's esophagus to esophageal adenocarcinoma.
In vitro and in vivo tumor suppressive activity induced by human telomerase transcriptase-targeting antisense oligonucleotides mediated by cationic liposomes.
Increased telomerase activities in human pancreatic duct adenocarcinomas.
Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.
Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection.
Inhibition of survivin reduces cell proliferation and induces apoptosis in human endometrial cancer.
Inhibition of telomerase activity by dominant-negative hTERT retards the growth of breast cancer cells.
Inhibition of telomerase by site-specific ribonucleases in gastric and esophageal adenocarcinoma.
Inhibitory effect of the tea polyphenol, (-)-epigallocatechin gallate, on growth of cervical adenocarcinoma cell lines.
Linoleic Acid-Induced Growth Inhibition of Human Gastric Epithelial Adenocarcinoma AGS Cells is Associated with Down-Regulation of Prostaglandin E2 Synthesis and Telomerase Activity.
Loss of ONECUT1 expression in human pancreatic cancer cells.
Lysophosphatidic acid activates telomerase in ovarian cancer cells through hypoxia-inducible factor-1alpha and the PI3K pathway.
Molecular diagnosis of pancreatic cancer.
Molecular Imaging of MDM2 Messenger RNA with 99mTc-Labeled Antisense Oligonucleotides in Experimental Human Breast Cancer Xenografts.
Oncornavirus-like particles released by human prostatic explant cultures.
Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3.
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Polyunsaturated fatty acids inhibit telomerase activity in DLD-1 human colorectal adenocarcinoma cells: a dual mechanism approach.
Progesterone receptor expression and proliferative activity in uterine tumours of pet rabbits.
Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis.
Quantitative analysis of survivin in colorectal adenocarcinoma: increased expression and correlation with telomerase activity.
Radiation-induced effects on telomerase in gynecological cancer cell lines with different radiosensitivity and repair capacity.
Real-time PCR quantification of human telomerase reverse transcriptase (hTERT) in colorectal cancer.
Semi-quantitative analysis of telomerase in pancreatic ductal adenocarcinoma.
Shortened telomere length and increased telomerase activity in hamster pancreatic duct adenocarcinomas and cell lines.
Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients.
Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.
Targeting protein kinase C (PKC) and telomerase by phenethyl isothiocyanate (PEITC) sensitizes PC-3 cells towards chemotherapeutic drug-induced apoptosis.
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Telomerase activation in a model of lung adenocarcinoma.
Telomerase activation--one step on the road to carcinoma of the gall bladder.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and patient survival after surgery for gastric and oesophageal cancer.
Telomerase activity as a marker for differential diagnosis of pancreatic adenocarcinoma: a systematic review and meta-analysis.
Telomerase activity could be used as a marker for neoplastic transformation in gastric adenocarcinoma: but it does not have a prognostic significance.
Telomerase activity in chronic inflammatory bowel disease.
Telomerase activity in different clinical staging of colorectal adenocarcinoma.
Telomerase Activity in Gastric Adenocarcinomas: Frozen Tissues Versus Methacarn-fixed Paraffin-embedded Tissues.
Telomerase activity in gynecological tumors.
Telomerase activity in human benign prostate tissue and prostatic adenocarcinomas.
Telomerase activity in pancreatic endocrine tumors.
Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
Telomerase activity in pancreatic juice differentiates pancreatic cancer from chronic pancreatitis: A meta-analysis.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity in small-cell and non-small-cell lung cancers.
Telomerase activity in thymomas and mammary gland adenocarcinomas induced by polyoma virus in AKR mice.
Telomerase activity is a useful marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts.
Telomerase activity of blood samples and recurrence of colorectal cancer.
Telomerase activity significantly correlates with cell differentiation, proliferation and lymph node metastasis in colorectal carcinomas.
Telomerase as a useful target in cancer fighting-the breast cancer case.
Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma.
Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cells.
Telomerase inhibition by siRNA causes senescence and apoptosis in Barrett's adenocarcinoma cells: mechanism and therapeutic potential.
Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells.
Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions.
Telomerase reactivation is associated with hepatobiliary and pancreatic cancers.
Telomerase reverse transcriptase (TERT) promoter mutations in primary adenocarcinoma of bladder and urothelial carcinoma with glandular differentiation: pathogenesis and diagnostic implications.
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence.
Telomerase, hTERT and splice variants in Barrett's oesophagus and oesophageal adenocarcinoma.
Telomere maintenance in laser capture microdissection-purified Barrett's adenocarcinoma cells and effect of telomerase inhibition in vivo.
TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer.
The association between telomerase, p53, and clinical staging in colorectal cancer.
The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration.
Tumor-specific apoptotic gene targeting overcomes radiation resistance in esophageal adenocarcinoma.
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization.
[Detection of telomerase activity in gastric cancer].
[Effect of selenium dioxide on proliferation, apoptosis, and elomerase activity of human lung cancer cell line in vitro]
[General rules for the study of pancreatic cancer by molecular biological aspect]
[Telomerase activity in association with the pathological differentiation of prostate cancer]
[Telomerase activity in human primary lung caner.]
[Telomere length and telomerase activity in intestinal metaplasia, adenoma and well differentiated adenocarcinoma of the stomach]
[The role of telomerase for pancreatic carcinogenesis in human and hamster]
Adenocarcinoma of Lung
A novel method to generate single-cell-derived cancer-associated fibroblast clones.
Bidirectional regulation of telomerase activity in a subline derived from human lung adenocarcinoma.
Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.
Combination of four gene markers to detect circulating tumor cells in the peripheral blood of patients with advanced lung adenocarcinoma using real-time PCR.
CPSF4 activates telomerase reverse transcriptase and predicts poor prognosis in human lung adenocarcinomas.
Discovery of a Novel Anti-Cancer Agent Targeting Both Topoisomerase I & II as well as Telomerase Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo: Cinnamomum verum Component Cuminaldehyde.
Efficacy of Pemetrexed-Based Chemotherapy in Patients with ROS1 Fusion-Positive Lung Adenocarcinoma Compared with in Patients Harboring Other Driver Mutations in East Asian Populations.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
Enhanced expression of telomerase activity in thymoma and thymic carcinoma tissues: a clinicopathologic study.
Functional impairment of telomerase in sublines derived from human lung adenocarcinoma exposed to mild oxidative stress.
Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma.
High expression of JMJD6 predicts unfavorable survival in lung adenocarcinoma.
HOXB2 as a novel prognostic indicator for stage I lung adenocarcinomas.
Identification of small molecule inhibitors of telomerase activity through transcriptional regulation of hTERT and calcium induction pathway in human lung adenocarcinoma A549 cells.
Indoleamine 2,3-dioxygenase 1 and programmed cell death-ligand 1 co-expression correlates with aggressive features in lung adenocarcinoma.
Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC.
MET Exon 14 Skipping Mutations in Lung Adenocarcinoma: Clinicopathologic Implications and Prognostic Values.
Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line.
n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2alpha and telomerase activity.
Newly identified biomarkers for detecting circulating tumor cells in lung adenocarcinoma.
Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells.
Silencing of the human TERT gene by RNAi inhibits A549 lung adenocarcinoma cell growth in vitro and in vivo.
Silencing tankyrase and telomerase promotes A549 human lung adenocarcinoma cell apoptosis and inhibits proliferation.
Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide.
Subtractive screening of genes involved in cellular senescence.
Telomerase activation in a model of lung adenocarcinoma.
Telomerase activity significantly correlates with chromosome alterations, cell differentiation, and proliferation in lung adenocarcinomas.
Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.
The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression.
Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line.
[A study on effects of cisplatin and its mechanisms on human lung adenocarcinoma SLC-89 cells.]
[Effect of tankyrase antisense oligonucleotide combined human telomerase reverse transcriptase antisense oligonucleotide on telomere dynamics in human lung adenocarcinoma A549 cells]
[Effects of matrine on the growth inhibition, c-myc and hTERT protein expression in human adenocarcinoma lung cancer cell line A549.]
[Effects of vinorelbine on apoptosis and expression of telomerase activity in human lung adenocarcinoma cells in vitro].
[Expression of hTERT mRNA in Anip973 and Anip973/NVB cell detected by quantitative real-time PCR]
[Expression of telomerase activity in thymoma and thymiccarcinoma tissues; a clinicopathological study]
[Significant correlation of telomerase activity in lung adenocarcinomas with cell differentiation and chromosome aberration]
Adenocarcinoma, Bronchiolo-Alveolar
Expression of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 2 (DYRK2) can be a favorable prognostic marker in pulmonary adenocarcinoma.
Expression of human telomerase RNA component and telomerase reverse transcriptase mRNA in atypical adenomatous hyperplasia of the lung.
Telomere length and telomerase expression in atypical adenomatous hyperplasia and small bronchioloalveolar carcinoma of the lung.
Adenocarcinoma, Clear Cell
Telomerase activity in gynecological tumors.
Adenocarcinoma, Follicular
A Clinical Overview of Telomerase-Associated Aberrancies in Follicular Thyroid Tumors as Diagnostic and Prognostic Markers: Tert Alert!
Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease.
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
Oncofoetal fibronectin--a tumour-specific marker in detecting minimal residual disease in differentiated thyroid carcinoma.
Thyroid carcinomas that express telomerase follow a more aggressive clinical course in children and adolescents.
Adenocarcinoma, Mucinous
Telomerase activity: comparison between fine-needle aspiration and biopsy specimens for the detection of tumor cells.
Adenocarcinoma, Scirrhous
[Telomerase activity in benign proliferative breast disease and breast cancer]
Adenolymphoma
[Detection of telomerase activity in salivary tumor and its significance]
Adenoma
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Alteration of telomerase activity associated with development and extension of epithelial ovarian cancer.
Cellular proliferative and telomerase activity in canine mammary gland tumors.
Change in telomerase activity during human colorectal carcinogenesis.
Clinical application of human telomerase reverse transcriptase gene expression in thyroid follicular tumors by fine-needle aspirations using in situ hybridization.
Consistent decrease in telomere length in parathyroid tumors but alteration in telomerase activity limited to malignancies: preliminary report.
Decrease of telomere length in thyroid adenomas without telomerase activity.
Demonstration of human telomerase reverse transcriptase (hTERT) in human parathyroid tumours by in situ hybridization with a new oligonucleotide probe.
Detection of circulating prostate derived cells in patients with prostate adenocarcinoma is an independent risk factor for tumor recurrence.
Detection of telomerase activity in biopsy samples of colorectal cancer.
Detection of telomerase activity in patients with pancreatic cancer.
Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma.
Expression of telomerase genes correlates with telomerase activity in human colorectal carcinogenesis.
Genetic diagnosis of pancreatic cancer.
Human telomerase reverse transcriptase expression in colorectal tumors: correlations with immunohistochemical expression and clinicopathologic features.
Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma.
Immunohistochemical detection of human telomerase reverse transcriptase in normal mucosa and precancerous lesions of the stomach.
In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormone-secreting human pituitary adenomas.
Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation.
Increased telomerase activity and hTERT expression in human salivary gland carcinomas.
Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.
Molecular-pathological diagnosis of gastrointestinal tissues and its contribution to cancer histopathology.
Nonradioisotopic telomeric repeat amplification protocol (TRAP) using digoxigenin labeled probe.
Patterns of gene expression in pituitary carcinomas and adenomas analyzed by high-density oligonucleotide arrays, reverse transcriptase-quantitative PCR, and protein expression.
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposis.
Preoperative diagnosis of intraductal papillary-mucinous tumors of the pancreas with attention to telomerase activity.
Progesterone receptor expression and proliferative activity in uterine tumours of pet rabbits.
Quantitative analysis of hTERT mRNA expression in colorectal cancer.
Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma.
Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension.
Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid.
Telomerase activation in colorectal carcinogenesis.
Telomerase activity and expression of telomerase RNA component and catalytic subunits in precancerous and cancerous colorectal lesions.
Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer.
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
Telomerase activity and p53 gene mutation in familial polyposis coli.
Telomerase activity and telomere length in benign and malignant human thyroid tissues.
Telomerase activity in benign and malignant adrenal tumors.
Telomerase activity in benign and malignant human thyroid tissues.
Telomerase activity in benign and malignant thyroid tumors.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in human thyroid carcinomas originating from the follicular cells.
Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
Telomerase activity in pituitary adenomas: significance of telomerase expression in predicting pituitary adenoma recurrence.
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Telomerase activity in the differentiation of benign and malignant adrenal tumors.
Telomerase activity in thyroid malignancy.
Telomerase activity is significantly enhanced in malignant adrenocortical tumors in comparison to benign adrenocortical adenomas.
Telomerase and N-Cadherin Differential Importance in Adrenocortical Cancers and Adenomas.
Telomerase elevation in pancreatic ductal carcinoma compared to nonmalignant pathological states.
Telomerase expression in sebaceous lesions of the skin.
Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions.
Telomere length and telomerase activity in carcinogenesis of the stomach.
The breakdown of apoptotic mechanism in the development and progression of colorectal carcinoma.
Variable expression of the transcription factors cAMP response element-binding protein and inducible cAMP early repressor in the normal adrenal cortex and in adrenocortical adenomas and carcinomas.
[Specific activation of telomerase in pancreatic cancer tissue and preoperative diagnosis of pancreatic cancer by telomerase in pancreatic juice]
[Telomerase activity and genomic instability in colorectal cancers]
[Telomerase activity in colorectal cancer--a semi-quantitative procedure]
[Telomerase activity in lung cancer and adjacent peritumoral tissues determined by TRAP-SYBR green assay]
[Telomerase activity in stool of patients with colorectal cancer]
[Telomerase expression in colorectal tubular adenoma determined by immunohistochemical staining]
[Telomere length and telomerase activity in intestinal metaplasia, adenoma and well differentiated adenocarcinoma of the stomach]
Adenoma, Liver Cell
Absence of correlation between telomerase activity and hepatic neoplasia in B6C3F1 mice.
Adenoma, Pleomorphic
Immunohistochemical evaluation of salivary gland tumors differentiation and proliferation by using calponin and telomerase.
Telomerase activity in oral cancer.
Adenomatous Polyposis Coli
Lack of telomerase in desmoids occurring sporadically and in association with familial adenomatous polyposis.
Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray.
Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposis.
Telomerase activity and p53 gene mutation in familial polyposis coli.
Adenomatous Polyps
Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis.
Evaluation of telomerase in the development and progression of colon cancer.
Evaluation of telomerase mRNA (hTERT) in colon cancer.
Molecular biology of colorectal cancer.
Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence.
Telomerase activity associated with acquisition of malignancy in human colorectal cancer.
Adenoviridae Infections
Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts.
Adrenal Cortex Neoplasms
Telomerase and N-Cadherin Differential Importance in Adrenocortical Cancers and Adenomas.
Telomerase is not required for experimental tumorigenesis of human and bovine adrenocortical cells.
Adrenocortical Adenoma
Telomerase activity in benign and malignant adrenal tumors.
Telomerase activity is significantly enhanced in malignant adrenocortical tumors in comparison to benign adrenocortical adenomas.
[Telomerase expression in various lesions of adrenal cortex]
Adrenocortical Carcinoma
Alternative lengthening of telomeres in the human adrenocortical carcinoma cell line H295R.
Telomerase activity as an indicator of potentially malignant adrenal tumors.
Telomerase activity in benign and malignant adrenal tumors.
TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma.
[Telomerase expression in various lesions of adrenal cortex]
African Swine Fever
Assessing the value of PCR assays in oral fluid samples for detecting African swine fever, classical swine fever, and foot-and-mouth disease in U.S. swine.
Agammaglobulinemia
Association of immune abnormalities with telomere shortening in autosomal-dominant dyskeratosis congenita.
Aggressive Periodontitis
Aggressive periodontitis: An appraisal of systemic effects on its etiology-genetic aspect.
Telomerase Expression in Subjects With Chronic and Aggressive Periodontitis.
AIDS Dementia Complex
HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir.
AIDS-Related Complex
Phase I/II study of 3TC (lamivudine) in HIV-positive, asymptomatic or mild AIDS-related complex patients: sustained reduction in viral markers. The Lamivudine European HIV Working Group.
Albinism, Oculocutaneous
Pigmentary disorders of the eyes and skin.
Alopecia
Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling.
[Experimental and clinical studies of mechanisms of the anti-aging effects of chemical compounds in Astragalus membranaceus (review).]
alpha-Thalassemia
alpha-and beta-Globin complementary deoxyribonucleic acids of human and rabbit. Specificity of hybridization.
Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas.
Hb Charlieu [alpha106(G13)Leu-->Pro (alpha1)]: a new phenotypically silent hemoglobin variant associated with a mild alpha-thalassemia phenotype.
Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors.
Alveolitis, Extrinsic Allergic
New trajectories in the treatment of interstitial lung disease: treat the disease or treat the underlying pattern?
Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease.
Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.
Alzheimer Disease
Beta-carotene, telomerase activity and Alzheimer's disease in old age subjects.
Both estrogen and raloxifene protect against beta-amyloid-induced neurotoxicity in estrogen receptor alpha-transfected PC12 cells by activation of telomerase activity via Akt cascade.
Brain-derived Neurotrophic Factor Signaling Pathway: Modulation by Acupuncture in Telomerase Knockout Mice.
Changes in expression of lymphocyte amyloid precursor protein mRNA isoforms in normal aging and Alzheimer's disease.
Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease.
Double negative (CD19(+)IgG(+)IgD(-)CD27(-)) B lymphocytes: A new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients.
Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy.
Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.
New horizons for diagnostics and therapeutic applications of graphene and graphene oxide.
Novel Neuroendocrine and Metabolic Mechanism Provides the Patented Platform for Important Rejuvenation Therapies: Targeted Therapy of Telomere Attrition and Lifestyle Changes of Telomerase Activity with the Timing of Neuron-Specific Imidazole-Containing Dipeptide-Dominant Pharmaconutrition Provision.
Pharmacogenetics to predict drug-related adverse events.
Telomere dysfunction of lymphocytes in patients with Alzheimer disease.
Telomeres and telomerase in Alzheimer's disease: Epiphenomena or a new focus for therapeutic strategy?
The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis.
The Role of Telomerase Protein TERT in Alzheimer's Disease and in Tau-Related Pathology In Vitro.
Ameloblastoma
Association between clincopathological characteristics and hTERT expression as well as telomere length in ameloblastoma.
Establishment of human dental epithelial cell lines expressing ameloblastin and enamelin by transfection of hTERT and cdk4 cDNAs.
Immortalization of ameloblastoma cells via reactivation of telomerase function: Phenotypic and molecular characteristics.
Telomerase activity and telomerase reverse transciptase (TERT) expression in ameloblastomas.
The basement membrane-type heparan sulfate proteoglycan (perlecan) in ameloblastomas: its intercellular localization in stellate reticulum-like foci and biosynthesis by tumor cells in culture.
[Characterization of growth and proliferation in a telomerase-immortalized ameloblastoma cell line]
[Expression of cyclin D1 and its inhibitors and hTERT in ameloblastoma]
[Expression of human telomerase reverse transcriptase and bcl-2 in ameloblastoma]
[Expression of pRb and E2F-1 and telomerase activity in ameloblastoma.]
[Expression of telomerase activity and c-myc and stimulatory protein 1 in human ameloblastoma]
[Expression of telomerase activity and cyclin A in ameloblastoma]
[Expression of telomerase and p53 in ameloblastoma]
Amyotrophic Lateral Sclerosis
Telomerase activity and expression in adult human mesenchymal stem cells derived from amyotrophic lateral sclerosis individuals.
Telomerase expression in amyotrophic lateral sclerosis (ALS) patients.
Telomere shortening leads to earlier age of onset in ALS mice.
Anaphylaxis
Large defects of type I allergic response in telomerase reverse transcriptase knockout mice.
Anemia
Characterization of RNA elements that regulate gag-pol ribosomal frameshifting in equine infectious anemia virus.
Developmental Therapeutics in Myeloproliferative Neoplasms.
DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts.
Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.
Factors associated with anaemia in HIV-infected individuals in southern India.
High Incidence of Zidovudine Induced Anaemia in HIV Infected Patients in Southern Odisha.
High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment.
Lack of mutations in the human telomerase RNA component (hTERC) gene in Fanconi's anemia.
Managing issues related to antiretroviral therapy.
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure.
Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.
RNA-dependent DNA polymerase associated with equine infectious anemia virus.
[Side effects of antiretroviral therapy]
[Study of telomerase activity and its related genes expression in leukemia cells]
Anemia, Aplastic
A molecular switch underlies a human telomerase disease.
A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria.
A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
Acquired Aplastic Anemia as a Clonal Disorder of Hematopoietic Stem Cells.
Aplastic anaemia and telomerase RNA mutations.
Association between aplastic anaemia and mutations in telomerase RNA.
Comprehensive structure-function analysis of the core domain of human telomerase RNA.
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs.
Detection of mutations in TERT, the genes for telomerase reverse transcriptase, in Indian patients of aplastic anaemia: a pilot study.
Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference.
Dyskeratosis congenita and telomerase.
Dyskeratosis congenita.
Dyskeratosis congenita: advances in the understanding of the telomerase defect and the role of stem cell transplantation.
Dyskeratosis congenita: its link to telomerase and aplastic anaemia.
Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies.
Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.
Fanconi Anemia germline variants as susceptibility factors in aplastic anemia, MDS and AML.
Functional characterization of novel telomerase RNA (TERC) mutations in patients with diverse clinical and pathological presentations.
Hepatitis Associated Aplastic Anemia: A review.
Heterozygous telomerase RNA mutations found in dyskeratosis congenita and aplastic anemia reduce telomerase activity via haploinsufficiency.
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita.
Lack of mutations of the human telomerase RNA gene (hTERC) in myelodysplastic syndrome.
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA.
Life and Death of Yeast Telomerase RNA.
Longitudinal data on telomere length in leukocytes from newborn baboons support a marked drop in stem cell turnover around 1 year of age.
Low frequency of telomerase RNA mutations among children with aplastic anemia or myelodysplastic syndrome.
Making the most of a little: dosage effects in eukaryotic telomere length maintenance.
Many disease-associated variants of hTERT retain high telomerase enzymatic activity.
Medical genetics and epigenetics of telomerase.
Mutations in telomerase catalytic protein in Japanese children with aplastic anemia.
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia.
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA.
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome.
Prognostic value of telomere attrition in patients with aplastic anemia.
Recent progress in dyskeratosis congenita.
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase.
Telomerase activity and its correlation with the proliferative potential of bone marrow in aplastic anemia in children.
Telomerase and cancer stem cells.
Telomerase gene mutation screening in Chinese patients with aplastic anemia.
Telomerase gene therapy rescues telomere length, bone marrow aplasia and survival in mice with aplastic anemia.
Telomerase mutations in aplastic anemia.
Telomerase mutations in families with idiopathic pulmonary fibrosis.
Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes.
Telomerase RNA biosynthesis and processing.
Telomerase RNA levels limit the telomere length equilibrium.
Telomere dynamics in mice and humans.
Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging.
Telomere length variation and telomerase activity expression in patients with congenital and acquired aplastic anemia.
Telomere length, stem cells and aging.
Telomeres in health and disease.
Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres.
Understanding telomere diseases through analysis of patient-derived iPS cells.
[Analysis for telomerase activity in various hematologic disorders]
[Expression of telomerase activity and its related genes in the marrow hemopoietic stem cells of children with aplastic anemia].
[The relationship of telomere and telomerase activity with outcome of aplastic anemia after immunesu pysessive therapy.]
Anemia, Hemolytic
alpha-and beta-Globin complementary deoxyribonucleic acids of human and rabbit. Specificity of hybridization.
Aneurysm
Polymorphisms of Pro-Inflammatory IL-6 and IL-1? Cytokines in Ascending Aortic Aneurysms as Genetic Modifiers and Predictive and Prognostic Biomarkers.
Red Blood Cell Distribution Width, Vascular Aging Biomarkers, and Endothelial Progenitor Cells for Predicting Vascular Aging and Diagnosing/Prognosing Age-Related Degenerative Arterial Diseases.
Telomere Biology and Thoracic Aortic Aneurysm.
Angiomyolipoma
Genetic changes and telomerase activity in human renal cell carcinoma.
Hepatic angiomyolipoma in a 26-year-old Caucasian woman with a history of tibial osteosarcoma.
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
Anthrax
Using molecular docking, 3D-QSAR, and cluster analysis for screening structurally diverse data sets of pharmacological interest.
Aortic Aneurysm
Long telomeres in blood leukocytes are associated with a high risk of ascending aortic aneurysm.
Telomere Biology and Thoracic Aortic Aneurysm.
Aortic Aneurysm, Abdominal
Telomerase deficiency in bone marrow-derived cells attenuates angiotensin II-induced abdominal aortic aneurysm formation.
Telomerase expression on aortic wall endothelial cells is attenuated in abdominal aortic aneurysms compared to healthy nonaneurysmal aortas.
Arrhythmias, Cardiac
Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients - Potential markers of ventricular arrhythmia.
[Animal in vivo model of arrhythmia for genes target identification for 5-amino-exo-3-azatricyclo[5.2.1.0(2,6)]decan-4-one].
Arthritis
Amelioration of experimental arthritis by a telomerase-dependent conditionally replicating adenovirus that targets synovial fibroblasts.
Arthritis, Rheumatoid
Abatacept suppresses the telomerase activity of lymphocytes in patients with rheumatoid arthritis.
Aggressive periodontitis: An appraisal of systemic effects on its etiology-genetic aspect.
Autoantibodies targeting telomere-associated proteins in systemic sclerosis.
Basic FGF-induced activation of telomerase in rheumatoid synoviocytes.
Different mechanisms of synovial hyperplasia in rheumatoid arthritis and pigmented villonodular synovitis: the role of telomerase activity in synovial proliferation.
Evaluation of synovial cytokine patterns in rheumatoid arthritis and osteoarthritis by quantitative reverse transcription polymerase chain reaction.
Evidence in patients with systemic lupus erythematosus of the presence of antibodies against RNA-dependent DNA polymerase of baboon endogenous virus.
Impaired activation-induced telomerase activity in PBMC of early but not chronic rheumatoid arthritis patients.
Longterm Culture of Telomerase-Transduced Rheumatoid Arthritis Fibroblast-like Synoviocytes Display a Distinct Gene Expression Pattern.
Telomerase activity in connective tissue diseases: elevated in rheumatoid arthritis, but markedly decreased in systemic sclerosis.
Telomerase activity in rheumatoid synovium correlates with the mononuclear cell infiltration level and disease aggressiveness of rheumatoid arthritis.
Telomerase insufficiency in rheumatoid arthritis.
Telomerase transduced osteoarthritis fibroblast-like synoviocytes display a distinct gene expression profile.
Telomere dysfunction, autoimmunity and aging.
The role of telomerase in joint deterioration in rheumatoid arthritis.
The telomere/telomerase system in autoimmune and systemic diseases.
Asbestosis
Telomerase gene variants and telomere shortening in patients with silicosis or asbestosis.
Asthma
Activation of telomerase is induced by a natural antigen in allergen-specific memory T lymphocytes in bronchial asthma.
Eosinophil cationic protein mRNA expression in children with bronchial asthma.
PINX1 and TERT Are Required for TNF-?-Induced Airway Smooth Muscle Chemokine Gene Expression.
Astrocytoma
Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma.
Beyond the World Health Organization classification of central nervous system tumors 2016: what are the new developments for gliomas from a clinician's perspective?
Cerebral granular cell astrocytomas: a Mib-1, bcl-2, and telomerase study.
Clinical significance of ABCA2' a possible molecular marker for oligodendrogliomas.
Correlation between IDH, ATRX, and TERT promoter mutations in glioma.
Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.
Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade.
Granulocyte colony-stimulating factor (G-CSF) production by astrocytoma cells and its effect on tumor growth.
Increased expression of telomerase RNA component is associated with increased cell proliferation in human astrocytomas.
Increased telomerase activity and absence of p53 mutation in oligoastrocytomas induced by N-ethyl-N-nitrosourea in rats.
Molecular diagnostics of gliomas using next generation sequencing of a glioma-tailored gene panel.
Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis.
Molecular Testing of Brain Tumor.
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Pilocytic Astrocytomas Have Telomere-Associated Promyelocytic Leukemia Bodies without Alternatively Lengthened Telomeres.
Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity level.
Prognostic significance of telomerase in brain tumors
Progression of astrocytomas and meningiomas: an evaluation in vitro.
PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma.
Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
Relative expression of human telomerase catalytic subunit (hTERT) transcripts in astrocytic gliomas.
RTEL1 and TERT polymorphisms are associated with astrocytoma risk in the Chinese Han population.
Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.
Survival of diffuse astrocytic glioma, IDH1/2-wildtype, with molecular features of glioblastoma, WHO grade IV: a confirmation of the cIMPACT-NOW criteria.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and hTERT mRNA expression in glial tumors.
Telomerase Activity in Human Brain Tumors: Astrocytoma and Meningioma.
Telomerase activity in human brain tumours.
Telomerase activity in human gliomas.
Telomerase expression in gliomas including the nonastrocytic tumors.
Telomerase expression in intracranial tumours: prognostic potential for malignant gliomas and meningiomas.
Telomerase expression shows differences across multiple regions of oligodendroglioma versus high grade astrocytomas but shows correlation with Mib-1 labelling.
Telomerase inhibition induces acute ATM-dependent growth arrest in human astrocytomas.
The role of aldehyde reductase AKR1A1 in the metabolism of gamma-hydroxybutyrate in 1321N1 human astrocytoma cells.
The significant role of telomerase activity in human brain tumors.
Ataxia
Introduction of Telomerase to Ataxia Teleangiectasia Cells Can Extend Shortend Telomere and Bypass Replicative Senescence.
Riccardin D, a Macrocyclic Bisbibenzy, Inhibits Human Breast Cancer Growth through the Suppression of Telomerase Activity.
Ataxia Telangiectasia
Arabidopsis ATM and ATR kinases prevent propagation of genome damage caused by telomere dysfunction.
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres.
Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression.
Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells.
Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion.
Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions.
DNA Repair Defect in AT Cells and their Hypersensitivity to Low-Dose-Rate Radiation.
Establishment of immortal normal and ataxia telangiectasia fibroblast cell lines by introduction of the hTERT gene.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors.
Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.
Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1.
Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.
Atherosclerosis
Activation of telomerase and expression of human telomerase reverse transcriptase in coronary atherosclerosis.
Aspirin inhibits human telomerase activation in unstable carotid plaques.
Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells.
Epigenetic control of telomerase and modes of telomere maintenance in aging and abnormal systems.
Evaluation of Energy Balance on Human Telomerase Reverse Transcriptase (hTERT) Alternative Splicing by Semi-quantitative RT-PCR in Human Umbilical Vein Endothelial Cells.
Evaluation of TERT mRNA alternative spliced variants in aortic endothelial cells of the rabbit, in the fatty streaks stage of atherosclerosis.
HIV-1 antiretrovirals induce oxidant injury and increase intima-media thickness in an atherogenic mouse model.
Injection of hTERT-Transduced Endothelial Progenitor Cells Promotes Beneficial Aortic Changes in a High-Fat Dietary Model of Early Atherosclerosis.
MicroRNA-216a promotes M1 macrophages polarization and atherosclerosis progression by activating telomerase via the Smad3/NF-?B pathway.
Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment.
Nucleoside reverse transcriptase inhibitors prevent HIV protease inhibitor-induced atherosclerosis by ubiquitination and degradation of protein kinase C.
Remnant like particles may induce atherosclerosis via accelerating endothelial progenitor cells senescence.
Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.
Short telomeres protect from diet-induced atherosclerosis in apolipoprotein E-null mice.
Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.
Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages.
Telomerase as a Therapeutic Target in Cardiovascular Disease.
Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells.
Telomerase, telomere length, and coronary artery calcium in black and white men in the CARDIA study.
The GG Genotype of Telomerase Reverse Transcriptase at Genetic Locus rs2736100 Is Associated with Human Atherosclerosis Risk in the Han Chinese Population.
Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress.
[Effects of Chinese herbal medicine Shoushen Granule on telomere length and telomerase activity of peripheral white blood cells and vascular cells in rats with atherosclerosis].
Atypical Squamous Cells of the Cervix
Clinical Role of the Detection of Human Telomerase RNA Component Gene Amplification by Fluorescence in situ Hybridization on Liquid-Based Cervical Samples: Comparison with Human Papillomavirus-DNA Testing and Histopathology.
Prediction of outcome in patients with low-grade squamous intraepithelial lesions by fluorescence in situ hybridization analysis of human papillomavirus, TERC, and MYC.
Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears.
Telomerase and human papillomavirus as diagnostic adjuncts for cervical dysplasia and carcinoma.
Autoimmune Diseases
An Autoantigen-ome from HS-Sultan B-Lymphoblasts Offers a Molecular Map for Investigating Autoimmune Sequelae of COVID-19.
Impaired activation-induced telomerase activity in PBMC of early but not chronic rheumatoid arthritis patients.
Mimicry between the hepatitis B virus DNA polymerase and the antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis B virus infection.
Telomerase activity in connective tissue diseases: elevated in rheumatoid arthritis, but markedly decreased in systemic sclerosis.
Telomere dysfunction, autoimmunity and aging.
Avian Leukosis
Comparison of the RNA-dependent DNA polymerase of an endogenous avian leukosis virus to the polymerase of an exogenous avian leukosis virus.
Generation of transforming viruses in cultures of chicken fibroblasts infected with an avian leukosis virus.
Isolation and characterization of a virus-specific ribonucleoprotein complex from reticuloendotheliosis virus-transformed chicken bone marrow cells.
Joint treatment with azidothymidine and antiserum for eradication of avian leukosis virus subgroup a contamination in vaccine virus seeds.
Marker rescue of endogenous cellular genetic information related to the avian leukosis virus gene encoding RNA-directed DNA polymerase.
Mutual regulation between chicken telomerase reverse transcriptase and the Wnt/?-catenin signalling pathway inhibits apoptosis and promotes the replication of ALV-J in LMH cells.
Proteolytic cleavage at the Gag-Pol junction in avian leukosis virus: differences in vitro and in vivo.
Reverse transcriptase and protease activities of avian leukosis virus Gag-Pol fusion proteins expressed in insect cells.
Reverse transcriptase associated with avian sarcoma-leukosis viruses. II. Comparison of subunit structure and catalytic properties.
Specific antigenic relationships between the RNA-dependent DNA polymerases of avian reticuloendotheliosis viruses and mammalian type C retroviruses.
Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas.
trans-acting viral protease is necessary and sufficient for activation of avian leukosis virus reverse transcriptase.
Azoospermia
Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA in testicular tissue of infertile patients.
Quantification of the expression level of the gene encoding the catalytic subunit of telomerase in testicular tissue specimens predicts successful sperm recovery.
Telomerase activity and expression of telomerase subunits in the testicular tissue of infertile patients.
Telomerase activity in the testis of infertile patients with selected causes.
Bacteremia
The detection of intraoperative bacterial translocation in the mesenteric lymph nodes is useful in predicting patients at high risk for postoperative infectious complications after esophagectomy.
Bacterial Infections
Immortalization of Fetal Bovine Colon Epithelial Cells by Expression of Human Cyclin D1, Mutant Cyclin Dependent Kinase 4, and Telomerase Reverse Transcriptase: An In Vitro Model for Bacterial Infection.
Stable expression in a Chinese hamster ovary (CHO) cell line of bioactive recombinant chelonianin, which plays an important role in protecting fish against pathogenic infection.
Barrett Esophagus
Alternative lengthening of telomeres is induced by telomerase inhibitors in Barrett's esophageal cells.
Cytotoxicity of chronic exposure to 4 cigarette smoke condensates in 2 cell lines.
Evidence for Enhanced Telomerase Activity in Barrett's Esophagus with Dysplasia and Adenocarcinoma.
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
GERD is associated with shortened telomeres in the squamous epithelium of the distal esophagus.
In situ hybridization for the detection of telomerase RNA in the progression from Barrett's esophagus to esophageal adenocarcinoma.
Oxidative DNA Damage in Barrett Mucosa: Correlation with Telomeric Dysfunction and p53 Mutation.
Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions.
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence.
Zoning of mucosal phenotype, dysplasia, and telomerase activity measured by telomerase repeat assay protocol in Barrett's esophagus.
beta-Thalassemia
alpha-and beta-Globin complementary deoxyribonucleic acids of human and rabbit. Specificity of hybridization.
Expression of human telomerase reverse transcriptase in bone marrow CD34+ cells from patients with beta-thalassemia major.
Premature senescence of T lymphocytes from patients with beta-thalassemia major.
Bile Duct Diseases
[Detection of telomerase activity of exfoliated cells in bile and its clinical impact]
Biliary Atresia
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
Biliary Tract Diseases
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Biliary Tract Neoplasms
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Detection of telomerase activity in biopsy specimens for diagnosis of biliary tract cancers.
Detection of telomerase activity in exfoliated cancer cells obtained from bile.
Detection of telomerase reverse transcriptase mRNA in biopsy specimens and bile for diagnosis of biliary tract cancers.
Blast Crisis
Activation of STAT5 confers imatinib resistance on leukemic cells through the transcription of TERT and MDR1.
Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells.
Cross-talk between Bcr-Abl tyrosine kinase, protein kinase C and telomerase-a potential reason for resistance to Glivec in chronic myelogenous leukaemia.
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression.
Telomerase activity in Philadelphia positive chronic myeloid leukaemia.
Telomere dynamics and genetic instability in disease progression of chronic myeloid leukemia.
Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy.
Blister
Human skin lymph derived from irritant and allergic contact dermatitis: interleukin 10 is increased selectively in elicitation reactions.
In vivo and in vitro evidence for autocrine DCoH/HNF-1alpha transcription of albumin in the human epidermis.
Bloom Syndrome
Telomerase activity in cell lines and lymphoma originating from Bloom syndrome.
Bluetongue
Bluetongue virus detection: a safer reverse-transcriptase polymerase chain reaction for prediction of viremia in sheep.
Identification of a novel bluetongue virus vector species of Culicoides in Sicily.
Identification of bluetongue virus serotype 2 (Corsican strain) by reverse-transcriptase PCR reaction analysis of segment 2 of the genome.
Bone Cysts
Telomerase activity in benign bone tumors and tumor-like lesions.
Bone Cysts, Aneurysmal
Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness.
Telomerase activity in benign bone tumors and tumor-like lesions.
Bone Diseases, Metabolic
Circular RNA hsa_circ_0001445 in plasma as a novel biomarker for osteoporosis in postmenopausal women.
Influence of Moxonidine and Bisoprolol on Morphofunctional Condition of Arterial Wall and Telomerase Activity in Postmenopausal Women with Arterial Hypertension and Osteopenia. The Results from a Moscow Randomized Study.
Bone Marrow Failure Disorders
A case of laryngeal carcinoma in a young adult with dyskeratosis congenita.
A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria.
A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome.
A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice.
Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of Dyskeratosis congenita.
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia.
Differences in disease severity but similar telomere lengths in genetic subgroups of patients with telomerase and shelterin mutations.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in hoyeraal-hreidarsson syndrome.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndrome.
DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts.
Dyskeratosis congenita and telomerase.
Dyskeratosis congenita and the DNA damage response.
Dyskeratosis congenita: a disorder of defective telomere maintenance?
Dyskeratosis congenita: molecular insights into telomerase function, ageing and cancer.
Dyskerin is a component of the arabidopsis telomerase RNP required for telomere maintenance.
Engineered telomere degradation models dyskeratosis congenita.
Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.
Erratum: Parry EM, Alder JK, Qi X, Chen JJ-L, Armanios M. Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase. Blood. 2011;117(21):5607-5611.
Fanconi Anemia germline variants as susceptibility factors in aplastic anemia, MDS and AML.
Functional characterization of telomerase RNA variants found in patients with hematologic disorders.
Hematopoietic stem cell development, aging and functional failure.
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.
Human telomerase RNA mutations and bone marrow failure.
Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.
InTERTpreting telomerase structure and function.
Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.
Lack of mutations of the human telomerase RNA gene (hTERC) in myelodysplastic syndrome.
Liver Transplantation for Decompensated Cirrhosis Secondary to Telomerase Reverse Transcriptase (TERT) Mutation.
Low frequency of telomerase RNA mutations among children with aplastic anemia or myelodysplastic syndrome.
Lung transplantation in telomerase mutation carriers with pulmonary fibrosis.
Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation.
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure.
Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.
Pulmonary fibrosis, bone marrow failure, and telomerase mutation.
Regulation of human telomerase in homeostasis and disease.
Senescence of hematopoietic stem cells and bone marrow failure.
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Short telomere syndromes cause a primary T cell immunodeficiency.
Short Telomere Syndromes in Clinical Practice: Bridging Bench and Bedside.
Short telomeres are sufficient to cause the degenerative defects associated with aging.
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies.
Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase.
Telomerase and idiopathic pulmonary fibrosis.
Telomerase as a clinical target: current strategies and potential applications.
Telomerase enzyme activity in Egyptian children with bone marrow failure and response to immunosuppressive therapy.
Telomerase gene mutation screening and telomere overhang detection in Chinese patients with acute myeloid leukemia.
Telomerase gene mutation screening in Chinese patients with aplastic anemia.
Telomerase gene mutations are associated with cirrhosis formation.
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis.
Telomerase therapeutics for degenerative diseases.
Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells.
Telomere elongation and clinical response to androgen treatment in a patient with aplastic anemia and a heterozygous hTERT gene mutation.
Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations.
Telomeres and disease.
TERC mutations in children with refractory cytopenia.
Variation at the TERT locus and predisposition for cancer.
[Aplastic anemia: Current state of diagnosis and treatment].
[Bone marrow failure due to telomerase complex gene mutations]
[Study on telomerase gene mutation in northern Chinese patients with acquired bone marrow failure syndromes.]
[Telomere length measurement of 10 Chinese patients with bone marrow failure syndrome.]
Bone Neoplasms
Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain.
Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients.
Bowen's Disease
Bowen's disease with high telomerase activity.
Evaluation of telomerase activity in non-genital Bowen's disease.
Telomerase activity in melanoma and non-melanoma skin cancer.
The higher incidence of squamous cell carcinoma in renal transplant recipients is associated with increased telomere lengths.
Brain Abscess
Distinct cytokine pattern in response to different bacterial pathogens in human brain abscess.
Brain Injuries
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.
Metallothionein (MT) -I and MT-II Expression Are Induced and Cause Zinc Sequestration in the Liver after Brain Injury.
Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons.
Seizures and tissue injury induce telomerase in hippocampal microglial cells.
Telomerase induction in astrocytes of Sprague-Dawley rat after ischemic brain injury.
Telomerase reverse transcriptase: A novel neuroprotective mechanism involved in neonatal hypoxic-ischemic brain injury.
Umbilical cord blood mesenchymal stem cells co-modified by TERT and BDNF: A novel neuroprotective therapy for neonatal hypoxic-ischemic brain damage.
[Effect of telomerase activation on biological behaviors of neural stem cells in rats with hypoxic-ischemic insults].
[The neuroprotective role of exogenous TERT gene in neonatal rats with hypoxic-ischemic brain damage].
Brain Injuries, Traumatic
Sexually Dimorphic Behavioral and Genetic Outcomes Associated With Administration of TA65 (A Telomerase Activator) Following Repetitive Traumatic Brain Injury: A Pilot Study.
Traumatic brain injury results in a concomitant increase in neocortical expression of vasopressin and its V(1a) receptor.
Brain Ischemia
Dysregulation of Autophagy, Mitophagy, and Apoptotic Genes in the Medial Temporal Lobe Cortex in an Ischemic Model of Alzheimer's Disease.
Immortalized Human Bone Marrow Derived Stromal Cells in Treatment of Transient Cerebral Ischemia in Rats.
[Effects of cerebellar fastigial nucleus electrical stimulation on telomerase reverse transcriptase expression and mitochondrial apoptotic pathway in rats with focal cerebral ischemia and reperfusion].
Brain Neoplasms
A telomerase assay detects brain tumor cells in blood.
Aberrant methylation of the TERT promoter in esophageal squamous cell carcinoma.
Can Dietary Antioxidants Reduce the Incidence of Brain Tumors?
Cellular immortality in brain tumours: An integration of the cancer stem cell paradigm.
Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors.
Correlation of clinical features and telomerase activity in human gliomas.
Curcumin as Prospective Anti-Aging Natural Compound: Focus on Brain.
Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells.
Detection of Brain Tumor Cells in the Peripheral Blood by a Telomerase Promoter-Based Assay.
Differential telomerase expression and telomere length in primary intracranial tumors.
Evidence for telomerase involvement in the angiogenesis of astrocytic tumors: expression of human telomerase reverse transcriptase messenger RNA by vascular endothelial cells.
Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.
Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells.
Glioblastoma induces vascular endothelial cells to express telomerase in vitro.
High incidence of TERT mutation in brain tumor cell lines.
Histone deacetylase inhibition attenuates cell growth with associated telomerase inhibition in high-grade childhood brain tumor cells.
Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas.
Implications of prognostic markers in brain tumors.
Increased telomerase activity and absence of p53 mutation in oligoastrocytomas induced by N-ethyl-N-nitrosourea in rats.
Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.
Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells.
Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk.
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163.
Part I. Telomerase levels in human metastatic brain tumors show four-fold logarithmic variability but no correlation with tumor type or interval to patient demise.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Particles with RNA of high molecular weight and RNA-directed DNA polymerase in human brain tumors.
Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells.
Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity level.
Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness.
Presence of telomerase activity with undetectable p16 gene mutation in Malaysian patients with brain tumor.
Prognostic implication of telomerase activity in patients with brain tumors.
Prognostic significance of telomerase in brain tumors
Promoter hypermethylation of TERT is associated with hepatocellular carcinoma in the Han Chinese population.
Suramin increased telomerase activity in the c6 glioma/wistar experimental brain tumor model.
Survivin in glioblastomas. Protein and messenger RNA expression and comparison with telomerase levels.
Targeting DNA-PKcs and telomerase in brain tumour cells.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and expression of telomerase reverse transcriptase correlated with cell proliferation in meningiomas and malignant brain tumors in vivo.
Telomerase activity and hTERT mRNA expression in glial tumors.
Telomerase activity and the expression of telomerase components in pituitary adenoma with malignant transformation.
Telomerase activity in 144 brain tumours.
Telomerase Activity in Human Brain Tumors: Astrocytoma and Meningioma.
Telomerase activity in human brain tumours.
Telomerase activity in microdissected human gliomas.
Telomerase downregulation in cancer brain stem cell.
Telomerase expression shows differences across multiple regions of oligodendroglioma versus high grade astrocytomas but shows correlation with Mib-1 labelling.
Telomerase in brain tumors.
Telomerase inhibitors for the treatment of brain tumors and the potential of intranasal delivery.
Telomerase reverse transcriptase (TERT) expression and proliferation in canine brain tumours.
The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas.
The significant role of telomerase activity in human brain tumors.
Breast Diseases
Culture models of human mammary epithelial cell transformation.
Quantitative determination of telomerase activity in breast cancer and benign breast diseases.
Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma.
[Telomerase activity in benign proliferative breast disease and breast cancer]
Breast Neoplasms
1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents.
A combination of the telomerase inhibitor, BIBR1532, and paclitaxel synergistically inhibit cell proliferation in breast cancer cell lines.
A comparison of the inhibitory effect of nano-encapsulated helenalin and free helenalin on telomerase gene expression in the breast cancer cell line, by real-time PCR.
A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity.
A human breast cancer model for the study of telomerase inhibitors based on a new biotinylated-primer extension assay.
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation.
A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGFbeta signaling for breast cancer therapy.
A novel and exploitable antifungal peptide from kale (Brassica alboglabra) seeds.
A Novel Prodrug of Epigallocatechin-3-gallate: Differential Epigenetic hTERT Repression in Human Breast Cancer Cells.
A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer.
A potential role for the estrogen-metabolizing cytochrome P450 enzymes in human breast carcinogenesis.
A robust cysteine-deficient chitinase-like antifungal protein from inner shoots of the edible chive Allium tuberosum.
A single quantum dot-based biosensor for telomerase assay.
A stable trypsin inhibitor from Chinese dull black soybeans with potentially exploitable activities.
A Static Magnetic Field Inhibits the Migration and Telomerase Function of Mouse Breast Cancer Cells.
A study on telomerase activity and prognosis in breast cancer.
A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women.
A trypsin-chymotrypsin inhibitor with antiproliferative activity from small glossy black soybeans.
Abcg2/Bcrp1 mediates the polarized transport of antiretroviral nucleosides abacavir and zidovudine.
Accuracy of telomerase in estimating breast cancer risk: a systematic review and meta-analysis.
Aloe emodin inhibits telomerase activity in breast cancer cells: transcriptional and enzymological mechanism.
AlphaCP1 mediates stabilization of hTERT mRNA by autocrine human growth hormone.
Alteration of hTERT full-length variant expression level showed different gene expression profiles and genomic copy number changes in breast cancer.
An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells.
An ultrasensitive and point-of-care sensor for the telomerase activity detection.
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells.
Antiproliferative Effects of Cucurbitacin B in Breast Cancer Cells: Down-Regulation of the c-Myc/hTERT/Telomerase Pathway and Obstruction of the Cell Cycle.
Antitumor and HIV-1 Reverse Transcriptase Inhibitory Activities of a Hemagglutinin and a Protease Inhibitor from Mini-Black Soybean.
Assessment of telomerase as drug target in breast cancer.
Association Between Human Telomerase Reverse Transcriptase Gene Variations and Risk of Developing Breast Cancer.
Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells.
Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells.
Biomarkers of aging associated with past treatments in breast cancer survivors.
Bisphosphonates decrease telomerase activity and hTERT expression in MCF-7 breast cancer cells.
Boldine, a natural aporphine alkaloid, inhibits telomerase at non-toxic concentrations.
Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3.
Brassiparin, an antifungal peptide from Brassica parachinensis seeds.
BRCA1 inhibition of telomerase activity in cultured cells.
Breast cancer biomarkers and molecular medicine.
Breast cancer biomarkers and molecular medicine: part II.
Breast cancer prognosis determined by gene expression profiling: a quantitative reverse transcriptase polymerase chain reaction study.
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.
BRIT1 regulates p53 stability and functions as a tumor suppressor in breast cancer.
Changes of Telomerase Activity and Proliferation by Inhibition of Reverse Transcriptase Activity in Human Cancer Cell.
Changes of telomerase activity by alternative splicing of full-length and beta variants of hTERT in breast cancer patients.
Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast.
Characterization of tree shrew telomeres and telomerase.
Circulating hTERT DNA in early breast cancer.
Clinical evaluation of a panel of mRNA markers in the detection of disseminated tumor cells in patients with operable breast cancer.
Clinical relevance of telomerase polymorphism for breast cancer: A systematic review.
Cognitive performance in survivors of breast cancer and markers of biological aging.
Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers.
Comparison of inhibitory effect of curcumin nanoparticles and free curcumin in human telomerase reverse transcriptase gene expression in breast cancer.
Complex roles for telomeres and telomerase in breast carcinogenesis.
Conclusions: future strategies in the treatment of breast cancer.
Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells.
Coordinate regulation between expression levels of telomere-binding proteins and telomere length in breast carcinomas.
Correlation between the expression of telomerase reverse transcriptase and proliferative activity in breast cancer cells using an immunocytochemical restaining method.
Correspondence re: S. M. Melana et al., Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine. Clin. Cancer Res., 4: 693-696, 1998.
Curcumin and silibinin inhibit telomerase expression in T47D human breast cancer cells.
Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line.
Curcumin sensitizes chemotherapeutic drugs via modulation of PKC, telomerase, NF-kappaB and HDAC in breast cancer.
Cyclo-oxygenase-2 (COX-2) mRNA expression correlates with progesterone receptor positivity in human breast cancer.
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.
Delivering antisense telomerase RNA by a hybrid adenovirus/ adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells.
Deregulation of estrogen induced telomerase activity in tamoxifen-resistant breast cancer cells.
Detection of bone sialoprotein in human breast cancer tissue and cell lines at both protein and messenger ribonucleic acid levels.
Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Comparison between MUC1 mRNA and keratin 19 mRNA amplification.
Detection of circulating tumor cells in patients with breast cancer using the quantitative RT-PCR assay for monitoring of therapy efficacy.
Detection of telomerase activity in breast masses by fine-needle aspiration.
Detection of telomerase RNA in the plasma of patients with breast cancer, malignant melanoma or thyroid cancer.
Determination of telomerase activity in stem cells and non-stem cells of breast cancer.
Development of a quantitative luminometric hybridization assay for the determination of telomerase activity.
Development of PEA-15 using a potent non-viral vector for therapeutic application in breast cancer.
Diagnostic value of telomerase expression in breast fine-needle aspiration biopsies.
Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells.
DNA flow cytometry but not telomerase activity as predictor of disease-free survival in pT1-2/N0/G2 breast cancer.
Down-regulation of telomerase activity after progesterone treatment of human breast cancer cells: essential role of the cell cycle status.
Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells.
Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.
Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer.
Effect of bisphenols on telomerase expression and activity in breast cancer cell lines.
Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) alpha+beta+ transcript in estrogen receptor-positive MCF-7 breast cancer cells.
Effect of estrogen on telomerase activity in human breast cancer cells.
Effect of procathepsin D activation peptide on gene expression of breast cancer cells.
Effective Targeted Gene Knockdown in Mammalian Cells Using the piggyBac Transposase-based Delivery System.
Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer.
Effects of chemopreventive and antitelomerase agents on the spontaneous immortalization of breast epithelial cells.
Effects of Ganoderma lucidum (Higher Basidiomycetes) Extracts on the miRNA Profile and Telomerase Activity of the MCF-7 Breast Cancer Cell Line.
Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells.
Effects of Reverse Transcriptase Inhibitors on Proliferation, Apoptosis, and Migration in Breast Carcinoma Cells.
Effects of Shugansanjie Tang on matrix metalloproteinases 1, 3 and 9 and telomerase reverse transcriptase expression in human breast cells in vitro.
Effects of tamoxifen on telomerase activity in breast carcinoma cell lines.
EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis.
Ellipticine binds to a human telomere sequence: an additional mode of action as a putative anticancer agent?
Emerging role of p53, bcl-2 and telomerase activity in Egyptian breast cancer patients.
Enterolactone Reduces Telomerase Activity and The Level of Its Catalytic Subunit in Breast Cancer Cells.
Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase.
Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.
Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent ?-H2AX and telomerase regulation in triple-negative breast cancer.
Erratum to: A combination of the telomerase inhibitor, BIBR1532, and paclitaxel synergistically inhibit cell proliferation in breast cancer cell lines.
Establishment and characterization of a new cell line derived from a human primary breast carcinoma.
Ets2 transcription factor in normal and neoplastic human breast tissue.
Ets2 Transcription Factor, Telomerase Activity And Breast Cancer.
Evasion of a single-step, chemotherapy-induced senescence in breast cancer cells: implications for treatment response.
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
Evidence for two forms of reverse transcriptase in human placenta of a patient with breast cancer. Purification and biochemical characterization of the enzymes.
Evidence of an autocrine role for leptin and leptin receptor in human breast cancer.
Expression and distribution of human telomerase catalytic component, hTERT, in human breast tissues.
Expression and prognostic relevance of Mcl-1 in breast cancer.
Expression distribution of cancer stem cells, epithelial to mesenchymal transition, and telomerase activity in breast cancer and their association with clinicopathologic characteristics.
Expression of human sequences related to those of mouse mammary tumor virus.
Expression of human telomerase reverse transcriptase gene and protein, and of estrogen and progesterone receptors, in breast tumors: preliminary data from neo-adjuvant chemotherapy.
Expression of telomerase genes in cancer development in atypical hyperplasia of the mammary duct.
Expression of the breast cancer resistance protein and 5-fluorouracil resistance in clinical breast cancer tissue specimens.
Familial melanoma and multiple primary melanoma.
Gefitinib induces apoptosis and decreases telomerase activity in MDA-MB-231 human breast cancer cells.
Gene expression for suppressors of telomerase activity (telomeric-repeat binding factors) in breast cancer.
Genetic changes associated with telomerase activity in breast cancer.
Genetic inhibition of telomerase results in sensitization and recovery of breast tumor cells.
Genetic polymorphisms in human telomerase reverse transcriptase (hTERT) gene polymorphisms do not associated with breast cancer in patients in a turkish population: hospital-based case-control study.
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms.
Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component.
Herbal complex suppresses telomerase activity in chemo-endocrine resistant cancer cell lines.
High BMI1 Expression with Low CD8+ and CD4+ T Cell Activity Could Promote Breast Cancer Cell Survival: A Machine Learning Approach.
hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells.
HTERT mRNA expression correlates with matrix metalloproteinase-1 and vascular endothelial growth factor expression in human breast cancer: a correlative study using RT-PCR.
hTERT mRNA expression correlates with telomerase activity in human breast cancer.
hTERT protein expression is independent of clinicopathological parameters and c-Myc protein expression in human breast cancer.
hTERT regulation by NF-?B and c-myc in irradiated HER2-positive breast cancer cells.
Human mammaglobin: a superior marker for reverse-transcriptase PCR in detecting circulating tumor cells in breast cancer patients.
Human telomerase and alpha-methylacyl-coenzyme A racemase in prostatic carcinoma. A comparative immunohistochemical study.
Identification of an RNA aptamer binding hTERT-derived peptide and inhibiting telomerase activity in MCF7 cells.
Impact of a 21-gene RT-PCR assay on treatment decisions in early-stage breast cancer: an economic analysis based on prognostic and predictive validation studies.
Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas.
In vitro quantification of the cytotoxic T lymphocyte response against human telomerase reverse transcriptase in breast cancer.
Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
Induction of cellular resistance to nucleoside reverse transcriptase inhibitors by the wild-type breast cancer resistance protein.
Influence of Mindfulness-Based Stress Reduction (MBSR) on Telomerase Activity in Women With Breast Cancer (BC).
Inhibition of breast carcinoma and trophoblast cell invasiveness by vascular endothelial growth factor.
Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine.
Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by retinoic acids.
Inhibition of Human Telomerase Reverse Transcritpase (hTERT) and Telomerase Activity by Curcumin in Human Mammary Epithelial and Breast Carcinoma Cell Lines.
Inhibition of telomerase activity by dominant-negative hTERT retards the growth of breast cancer cells.
Inhibitory effects of costunolide on the telomerase activity in human breast carcinoma cells.
Intercellular traffic of human immunodeficiency virus type 1 transactivator protein defined by monoclonal antibodies.
Investigation of the effect of telomerase inhibitor BIBR1532 on breast cancer and breast cancer stem cells.
Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer?
Isolation and characterization of a lectin with potentially exploitable activities from caper (Capparis spinosa) seeds.
Isolation and Characterization of Juncin, an Antifungal Protein from Seeds of Japanese Takana ( Brassica juncea Var. integrifolia).
Isolation and identification of a novel polysaccharide-peptide complex with antioxidant, antiproliferative, and hypoglycemic activities from the abalone mushroom.
Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells.
Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients.
Lipid transfer proteins from Brassica campestris and mung bean surpass mung bean chitinase in exploitability.
Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab.
Long-term exposure to MST-312 leads to telomerase reverse transcriptase overexpression in MCF-7 breast cancer cells.
Long-term in vitro treatment with telomerase inhibitor MST-312 induces resistance by selecting long telomeres cells.
Loss of RAB25 expression in breast cancer.
Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase.
Marmorin, a new ribosome inactivating protein with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from the mushroom Hypsizigus marmoreus.
Maspin and mammaglobin genes are specific markers for RT-PCR detection of minimal residual disease in patients with breast cancer.
Melatonin, an inhibitory agent in breast cancer.
miR-221/222: promising biomarkers for breast cancer.
Molecular detection and prognostic value of circulating cytokeratin-19 messenger RNA-positive and HER2 messenger RNA-positive cells in the peripheral blood of women with early-stage breast cancer.
Molecular detection of telomerase-positive circulating epithelial cells in metastatic breast cancer patients.
Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro.
MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells.
Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray.
MYC amplification and TERT expression in breast tumor progression.
Novel siRNA-based molecular beacons for dual imaging and therapy.
Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice.
p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells.
PES1 is a critical component of telomerase assembly and regulates cellular senescence.
Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment.
Plumbagin triggers DNA damage response, telomere dysfunction and genome instability of human breast cancer cells.
Polymorphisms in the telomerase reverse transcriptase promoter are associated with risk of breast cancer: A meta-analysis.
Preparation of monoclonal antibodies against human telomerase.
Prevalence and prognostic and predictive relevance of PRAME in breast cancer.
Prevalence of telomerase activity in human cancer.
Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer.
Prognostic significance of disseminated tumor cells as detected by quantitative real-time reverse-transcriptase polymerase chain reaction in patients with breast cancer.
Prognostic significance of reactivation of telomerase in breast core biopsy specimens.
Progress in the development of a therapeutic vaccine for breast cancer.
Prostate-specific antigen gene expression and telomerase activity in breast cancer patients: possible relationship to steroid hormone receptors.
Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells.
PTOP and TRF1 help enhance the radio resistance in breast cancer cell.
Purification and characterization of a laccase from the edible wild mushroom Tricholoma mongolicum.
Purification and Characterization of an Antifungal Peptide with Potent Antifungal Activity but Devoid of Antiproliferative and HIV Reverse Transcriptase Activities from Legumi Secchi Beans.
Purification of melibiose-binding lectins from two cultivars of Chinese black soybeans.
Quantitative determination of telomerase activity in breast cancer and benign breast diseases.
Raloxifene inhibits estrogen-induced up-regulation of telomerase activity in a human breast cancer cell line.
Re: Poremba et al Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hTERT and hTR. J Pathol 2002; 198: 181-189.
Re: Telomerase activity in human breast tumors.
Real-time quantitative analysis of telomerase activity in breast tumor specimens using a highly specific and sensitive fluorescent-based assay.
Recent advances in breast cancer biology.
Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.
Relationship between dyskerin expression and telomerase activity in human breast cancer.
Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance.
Resveratrol down-regulates the growth and telomerase activity of breast cancer cells in vitro.
Retinoid-induced histone deacetylation inhibits telomerase activity in estrogen receptor-negative breast cancer cells.
Retraction. Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3.
Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination.
Ribozyme cleavage of telomerase mRNA sensitizes breast epithelial cells to inhibitors of topoisomerase.
Riccardin D, a Macrocyclic Bisbibenzy, Inhibits Human Breast Cancer Growth through the Suppression of Telomerase Activity.
RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line.
RNA-directed DNA polymerase activity in human breast cancer biopsy specimens. Relation to estrogen receptor protein.
Role of melatonin in the epigenetic regulation of breast cancer.
Role of RIN1 on telomerase activity driven by EGF-Ras mediated signaling in breast cancer.
Sensitive detection of circulating breast cancer cells by reverse-transcriptase polymerase chain reaction of maspin gene.
Sensitive detection of human telomerase reverse transcriptase mRNA in the serum of patients with hepatocellular carcinoma.
Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction.
Sequence homology of deoxyribonucleic acid to mouse mammary tumor virus genome in human breast tumors.
Serum human telomerase reverse transcriptase: a novel biomarker for breast cancer diagnosis.
Serum tRNA-derived fragments (tRFs) as potential candidates for diagnosis of nontriple negative breast cancer.
Shorter telomeres and high telomerase activity correlate with a highly aggressive phenotype in breast cancer cell lines.
siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells.
Stratification Using hTERT and Stem Cell Markers Confers a Good Prognosis in Invasive Breast Cancer.
Studies on the purification of polypeptide from sika antler plate and activities of antitumor.
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.
SUMO E3 ligase CBX4 regulates hTERT-mediated transcription of CDH1 and promotes breast cancer cell migration and invasion.
Suppression of cell proliferation and telomerase activity in 4-(hydroxyphenyl)retinamide-treated mammary tumors.
Systematic determination of telomerase activity and telomerase length during the progression of human breast cancer in cell culture models.
Targeted BikDD expression kills androgen-dependent and castration-resistant prostate cancer cells.
Targeted Expression of BikDD Eliminates Breast Cancer with Virtually No Toxicity in Noninvasive Imaging Models.
Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes.
Telomerase activation in neoplastic cell immortalization and tumour progression.
Telomerase activity and Bcl-2 expression in human breast cancer.
Telomerase activity and genetic alterations in primary breast carcinomas.
Telomerase activity and lymphovascular invasion in breast cancer.
Telomerase activity and prognosis in breast cancer.
Telomerase activity and prognosis in primary breast cancers.
Telomerase activity and survival of patients with node-positive breast cancer.
Telomerase activity and telomere lengths in various cell lines: changes of telomerase activity can be another method for chemosensitivity evaluation.
Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples.
Telomerase activity as a marker of invasive ductal breast carcinomas on FNABs and relationship to other prognostic variables.
Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer.
Telomerase activity in breast cancer in Western India (Gujarat).
Telomerase activity in breast cancer patients: association with poor prognosis and more aggressive phenotype.
Telomerase activity in ductal carcinoma in situ and invasive breast cancer.
Telomerase activity in ductal carcinoma in situ of the breast.
Telomerase activity in gestational trophoblastic disease.
Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.
Telomerase activity in human breast tumors.
Telomerase activity in human proliferative breast lesions.
Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome.
Telomerase activity in normal and neoplastic breast.
Telomerase activity in relation to p53 status and clinico-pathological parameters in breast cancer.
Telomerase activity is associated with cell cycle deregulation in human breast cancer.
Telomerase activity levels for evaluating the surgical margin in breast-conserving surgery.
Telomerase activity, and tissue polypeptide specific antigen (TPS) in Egyptian breast cancer patients.
Telomerase activity, estrogen receptors (alpha, beta), Bcl-2 expression in human breast cancer and treatment response.
Telomerase and breast cancer.
Telomerase and breast cancer: from diagnosis to therapy.
Telomerase as a Possible Candidate Targeting Therapy in Different Breast Cancer Cell Lines.
Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hTERT and hTR.
Telomerase as a useful target in cancer fighting-the breast cancer case.
Telomerase downregulation induces proapoptotic genes expression and initializes breast cancer cells apoptosis followed by DNA fragmentation in a cell type dependent manner.
Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma.
Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells.
Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome.
Telomerase expression in human breast cancer with and without lymph node metastases.
Telomerase in breast cancer: a critical evaluation.
Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells.
Telomerase inhibition regulates EMT mechanism in breast cancer stem cells.
Telomerase is controlled by protein kinase Calpha in human breast cancer cells.
Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells.
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells.
Telomerase RNA as a detection marker in the serum of breast cancer patients.
Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.
Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation.
Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients.
TERT attenuated ER stress-induced cell death.
TERT polymorphisms rs2853669 and rs7726159 influence on prostate cancer risk in Russian population.
TERT regulates cell survival independent of telomerase enzymatic activity.
TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.
The association between telomerase activity and expression of its RNA component (hTR) in breast cancer patients: the importance of DNase treatment.
The association between telomerase activity and hormone receptor status and p53 expression in breast cancer.
The association between telomerase, histopathological parameters, and KI-67 expression in breast cancer.
The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.
The co-expression of telomerase and ALT pathway in human breast cancer tissues.
The correlation between telomerase activity and Bax/Bcl-2 ratio in valproic acid-treated MCF-7 breast cancer cell line.
The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.
The effect of environmental Bisphenol A exposure on breast cancer associated with obesity.
The effect of raloxifene on telomerase expression in breast carcinoma samples from postmenopausal women.
The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells.
The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cells.
The role of breast cancer resistance protein (BCRP/ABCG2) in cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.
The role of interferon-gamma and vitamin-A in modulating telomerase activity in breast cancer patients.
The role of telomerase in breast cancer.
The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2(+) breast cancer cells.
The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel.
The value of telomerase assay in breast cancer.
There is no correlation between c-Myc mRNA expression and telomerase activity in human breast cancer.
Tissue-specific promoters active in CD44+CD24-/low breast cancer cells.
Transcription and alternative splicing of telomerase reverse transcriptase in benign and malignant breast tumours and in adjacent mammary glandular tissues: implications for telomerase activity.
Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines.
Troglitazone suppresses telomerase activity independently of PPARgamma in estrogen-receptor negative breast cancer cells.
Update in genetic susceptibility in melanoma.
Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf.
Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).
Use of reverse-transcriptase polymerase chain reaction (RT-PCR) for carcinoembryonic antigen, cytokeratin 19, and maspin in the detection of tumor cells in leukapheresis products from patients with breast cancer: comparison with immunocytochemistry.
Wild-type p16INK4a suppresses cell growth, telomerase activity and DNA repair in human breast cancer MCF-7 cells.
ZEB1 stimulates breast cancer growth by up-regulating hTERT expression.
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity.
[Analysis for telomerase activity in various hematologic disorders]
[Changes in telomerase activity decreases in MCF-7 cells during apoptosis induced by sodium butyrate]
[Cleavage of telomerase RNA component by two DNAzymes and their effects on expression of two apoptosis-related genes in human mammary cancer cells]
[Clinical implications of telomerase activity in breast cancer fine-needle aspirates]
[Construction of an expression vector carrying short hairpin RNA targeting hTERT gene and its effects on breast cancer cell telomerase activity and proliferation in vivo]
[Current status of breast cancer chemoprevention]
[Detection of breast cancer micrometastases in lymph nodes by amplification of keratin 19 mRNA with reverse-transcriptase polymerase chain reaction]
[Effect of HSP90 function inhibited on the telomerase and P53 mutant in breast cancer cells]
[Effects of a novel antiprogestin derivative ZXH951 on proliferation and telomerase activity of human breast carcinoma cell lines]
[Enhanced thymidine kinase gene vector and its killing effect on nasopharyngeal carcinoma in vitro and in vivo].
[Expression of telomerase genes in human tumors]
[Expression of telomerase genes in mamary atypical ductal hyperplasia]
[Inhibitory effect of telomerase inhibitors combined with X-irradiation on bone marrow hematopoiesis in mice]
[Inhibitory mechanism on growth of MA-891 cells by arsenic trioxide].
[Quantitative detection of telomerase activity and its association with clinicopathological characteristics in breast cancer]
[Relationship between expressions of telomerase genes and apoptosis related genes in mammary ductal atypical hyperplasia]
[Significance of telomerase activity detection by fine-needle aspiration in patients with breast cancer]
[Significance of telomerase expression in diagnosis and treatment of breast tumor]
[Study on the relationship between TK gene regulated by enhanced suicide gene vector and telomerase activity in nasopharyngeal carcinoma cells]
[Telomerase activity in benign proliferative breast disease and breast cancer]
[Telomerase activity in breast carcinoma]
[Telomerase activity in gastrointestinal, bladder and breast carcinomas and their clinical applications]
[Telomerase activity in infiltration ductal carcinoma of breast]
[The inhibitory effect of antisense adenovirus vector of telomerase on telomerase activity in breast cancer cells MCF-7]
Bronchiolitis, Viral
Viral Bronchiolitis is Associated with Altered Cytokine Gene Expression and Lymphocyte Activation Status.
Bronchitis
Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung.
Bronchitis, Chronic
[Determination of telomerase activity in BALF cells from lung cancer patients]
Burkitt Lymphoma
A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of Burkitt's lymphoma cells in vitro and in vivo.
Atypical protein-kinase Czeta, but neither conventional Ca2+ -dependent protein-kinase C isoenzymes nor Ca2+ -calmodulin, participates in regulation of telomerase activity in Burkitt's lymphoma cells.
Dimethyl sulfoxide (DMSO) causes a reversible inhibition of telomerase activity in a Burkitt lymphoma cell line.
Selective killing of Burkitt's lymphoma cells by mBAFF-targeted delivery of PinX1.
Short telomeres limit tumor progression in vivo by inducing senescence.
Telomere dysfunction and inactivation of the p16(INK4a)/Rb pathway in pyothorax-associated lymphoma.
Telomere size and telomerase activity in Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cell lines.
[Telomere DNA and telomerase of lymphoma-derived cell lines--telomere hypothesis for cell growth control]
Buschke-Lowenstein Tumor
Telomerase activity in giant condyloma acuminatum.
Caliciviridae Infections
Allogeneic hematopoietic stem cell transplantation and norovirus gastroenteritis: a previously unrecognized cause of morbidity.
Apparently non-specific results found using a norovirus antigen immunoassay for fecal specimens from neonates.
Candidiasis
Antiretroviral therapy with protease inhibitors has an early, immune reconstitution-independent beneficial effect on Candida virulence and oral candidiasis in human immunodeficiency virus-infected subjects.
Candidiasis, Oral
Isolation and characterization of the Candida albicans MOT2 gene.
Capsule Opacification
[Expression and significance of telomerase activity of lens epithelial cells in posterior capsule opacification of rabbits]
Carcinogenesis
9-Hydroxyellipticine inhibits telomerase activity in human pancreatic cancer cells.
A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis.
A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin.
A comparative study of telomerase activity and malignant phenotype in multistage carcinogenesis of esophageal epithelial cells induced by human papillomavirus.
A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis.
A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
A molecular switch underlies a human telomerase disease.
A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation.
A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias.
A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer.
A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters.
A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis.
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
Aberrant telomerase expression in the endometrium of infertile women with deep endometriosis.
Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.
Accuracy of telomerase in cervical lesions: a systematic review.
Acidified bile acids increase hTERT expression via c-myc activation in human gastric cancer cells.
Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse.
Activation of telomerase by human cytomegalovirus.
Activation of telomerase in BeWo cells by estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin in co-operation with c-Myc.
Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients.
Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription.
Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat).
AKT plays a crucial role in gastric cancer.
Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions.
Alternative lengthening of telomeres (ALT) and chromatin: is there a connection?
Alternative lengthening of telomeres frequently occurs in mismatch repair system-deficient gastric carcinoma.
Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis in vivo.
Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers.
ALV Integration-Associated Hypomethylation at the TERT Promoter Locus.
Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase.
Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer.
Amplification of TERT and TERC genes in cervical intraepithelial neoplasia and cervical cancer.
Amplification of the telomerase RNA component gene in the process of human esophageal carcinogenesis.
An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells.
Analysis of DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis.
Analysis of telomerase activity and telomere length in bone and soft tissue tumors.
Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors, and invasive carcinomas.
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
Androgen depletion activates telomerase in the prostate of the nonhuman primate, Macaca mulatta.
Androgens stimulate telomerase expression, activity and phosphorylation in ovarian adenocarcinoma cells.
Anticancer Potential and Mechanism of Action of Mango Ginger (Curcuma amada Roxb.) Supercritical CO2 Extract in Human Glioblastoma Cells.
Antidepressants, prostaglandins and the prevention and treatment of cancer.
Antiproliferative effects of the major tea polyphenol, (-)-epigallocatechin gallate and retinoic acid in cervical adenocarcinoma.
Antisense hTERT inhibits thyroid cancer cell growth.
Antisense telomerase RNA inhibits the growth of human glioma cells in vitro and in vivo.
Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation.
Antisense-mediated hTERT inhibition specifically reduces the growth of human bladder cancer cells.
Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors.
Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells.
Application of telomerase assay for the screening of cervical lesions.
Arsenic inhibition of telomerase transcription leads to genetic instability.
ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells.
Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk.
Association of p53 gene mutation and telomerase activity in resectable non-small cell lung cancer.
ATM protein overexpression in prostate tumors: possible role in telomere maintenance.
Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells.
Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis.
Bile duct cyst as precursor to biliary tract cancer.
Biological characterization of long-term cultured human mesenchymal stem cells.
BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells.
Bronchogenic and alveologenic tumors in mice induced by N-nitrosopiperidine.
C-erbB-2 or mutant Ha-ras induced malignant transformation of immortalized human ovarian surface epithelial cells in vitro.
c-MYC and h-TERT co-expression in colon adenocarcinoma: a tissue microarray digitized image analysis.
C-terminal p73 isoforms repress transcriptional activity of the human telomerase reverse transcriptase (hTERT) promoter.
Cancer stem cell-like characteristics and telomerase activity of the nasopharyngeal carcinoma radioresistant cell line CNE-2R.
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications.
Canis familiaris telomerase reverse transcriptase undergoes alternative splicing.
Cascaded Electrochemiluminescence Signal Amplifier for the Detection of Telomerase Activity from Tumor Cells and Tissues.
Catalytically inactive telomerase in oncogenesis.
CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation.
Change in telomerase activity during human colorectal carcinogenesis.
Changes of the alternative splicing variants of human telomerase reverse transcriptase during gastric carcinogenesis.
Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.
Chemoprevention by naturally occurring and synthetic agents in oral, liver, and large bowel carcinogenesis.
Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer.
Clinical implications of telomerase in cancer.
Clinical Significance of Human Telomerase RNA Gene (hTERC) Amplification in Cervical Squamous Cell Lesions Detected by Fluorescence in Situ Hybridization.
Clinical significance of telomerase genes (hTERC and hTERT) amplification in patients with acute myeloid leukemia.
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.
Cloning and expression of hamster telomerase catalytic subunit cDNA.
Cloning of hTERT cDNA fragment and application of anti-hTERT monoclonal antibody in mechanism of laryngeal carcinogenesis.
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells.
Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis.
Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion.
Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours.
Comparison of human telomerase reverse transcriptase messenger RNA and telomerase activity as urine markers for diagnosis of bladder carcinoma.
Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?
Complex roles for telomeres and telomerase in breast carcinogenesis.
Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development.
Cooperative role of telomerase activity and p16 expression in the prognosis of non-small-cell lung cancer.
Correlating telomerase activity levels with human neuroblastoma outcomes.
Correlation between telomerase activity and telomeric-repeat binding factors in gastric cancer.
Correlation of dyskerin expression with active proliferation independent of telomerase.
Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression.
Correlation of telomerase activity to apoptosis and survival in adult acute lymphoblastic leukemia: an Egyptian single-center study.
Correlation of telomerase activity, clinical prognosis and therapy in oral carcinogenesis.
Correlation of TERT and Stem Cell Markers in the Context of Human Breast Cancer.
Correlation of the expression of telomerase RNA with risk factors for recurrence of sebaceous gland carcinoma.
CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia.
CpG island methylator phenotype association with upregulated telomerase activity in hepatocellular carcinoma.
Craniopharyngiomas, including Recurrent Cases, Lack TERT Promoter Hotspot Mutations.
Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity.
Cytogenetic aberrations in immortalization of esophageal epithelial cells.
Cytogenetics in head and neck cancer.
Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.
Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors.
Decreased gene expression for telomeric-repeat binding factors and TIN2 in malignant hematopoietic cells.
Decreased telomerase activity is not a reliable indicator of chemosensitivity in testicular cancer cell lines.
Demethylating reagent 5-azacytidine inhibits telomerase activity in human prostate cancer cells through transcriptional repression of hTERT.
Demonstration of human telomerase reverse transcriptase by in situ hybridization in lung carcinoma.
Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization.
Detection of DNA strand breaks, DNA-protein crosslinks, and telomerase activity in nickel-transformed BALB/c-3T3 cells.
Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer.
Detection of telomerase activity and correlation with mitotic and apoptotic indices, Ki-67 and expression of cyclins D1 and A in cutaneous melanoma.
Detection of telomerase activity in biopsy samples of colorectal cancer.
Detection of telomerase activity in patients with mycosis fungoides.
Detection of telomerase activity in prostate cancer by needle biopsy.
Detection of telomerase activity in prostate needle-biopsy samples.
Detection of telomerase activity in tissues and primary cultured lymphoid cells of Penaeus japonicus.
Detection of TERC amplification in cervical epithelial cells for the diagnosis of high-grade cervical lesions and invasive cancer: a multicenter study in China.
Detection of the presence of catalytic subunit mRNA associated with telomerase gene in exfoliated urothelial cells from patients with bladder cancer.
Diagnosis of bladder cancer using telomerase activity in voided urine.
Diagnostic and therapeutic application of telomerase-specific oncolytic adenoviral agents.
Diagnostic performance of HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR assays on formalin-fixed paraffin-embedded cervical tissue specimens from women with cervical cancer.
Diagnostic roles of proliferative markers in pathological Grade of T1 Urothelial Bladder Cancer.
Different effects of interferon-alpha on melanoma cell lines: a study on telomerase reverse transcriptase, telomerase activity and apoptosis.
Different TERT Expression between Colorectal Adenoma and Serrated Polyp.
Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions.
Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma.
Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma, and glioma cells in culture.
Differential Lysis of Tumors by Polyclonal T Cell Lines and T Cell Clones Specific for hTERT.
Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis.
Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer.
Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis.
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis.
Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model.
DNA G-quadruplexes, telomere-specific proteins and telomere-associated enzymes as potential targets for new anticancer drugs.
DNA methylation is not likely to be responsible for hTERT expression in premalignant cervical lesions.
DNA Methylation Profiling of hTERT Gene Alongside with the Telomere Performance in Gastric Adenocarcinoma.
DNA repair factors and telomere-chromosome integrity in mammalian cells.
Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells.
Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression.
E2F1 acts as a negative feedback regulator of c-Myc?induced hTERT transcription during tumorigenesis.
Early growth response-1 mediates up-regulation of telomerase in placenta.
Editorial Comment from Dr Kurobe to Telomerase reverse transcriptase promoter mutation in tumorigenesis of bladder cancer: Evolutionary trajectory by algorithmic inference from cross-sectional data.
Editorial Comment from Dr Urabe to Telomerase reverse transcriptase promoter mutation in tumorigenesis of bladder cancer: Evolutionary trajectory by algorithmic inference from cross-sectional data.
Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells.
Effect of RNA interference targeting human telomerase reverse transcriptase on telomerase and its related protein expression in nasopharyngeal carcinoma cells.
Effects of cadmium on telomerase activity, expressions of TERT, c-myc and P53, and apoptosis of rat hepatocytes.
Effects of genomic imbalances on telomerase activity in gastric cancer: clues to telomerase regulation.
Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells.
Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers.
Effects of telomerase activity on carcinogenesis and survival in laryngeal carcinoma.
Efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from TERT.
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.
Elevated expression of hTERT is associated with dysplastic cell transformation during human oral carcinogenesis in situ.
Elevated human telomerase reverse transcriptase gene expression in blood cells associated with chronic arsenic exposure in Inner Mongolia, China.
Emerging immunotherapeutic strategies targeting telomerases in genitourinary tumors.
Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.
Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells.
Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention.
Epigenetic control of telomerase and modes of telomere maintenance in aging and abnormal systems.
Epigenetic linkage of aging, cancer and nutrition.
Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review).
Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion.
Epigenetic targets of bioactive dietary components for cancer prevention and therapy.
Establishing Cell-Based Reporter Systems for the Analysis of hTERT Expression.
Estrogen activates telomerase.
Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells.
Estrogen, Telomerase, Ovarian Aging And Cancer.
Estrogen-receptor-dependent regulation of telomerase activity in human endometrial cancer cell lines.
Evaluation of combined telomerase and c-myc expression in non-small cell lung carcinomas using tissue microarrays and computerized image analysis.
Evaluation of telomerase activation in head and neck cancer.
Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter.
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
Evidence for UV-associated activation of telomerase in human skin.
Evolving views of telomerase and cancer.
Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer.
Expression and distribution of human telomerase catalytic component, hTERT, in human breast tissues.
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.
Expression of human telomerase catalytic protein in gallbladder carcinogenesis.
Expression of human telomerase catalytic subunit gene in cancerous and precancerous gastric conditions.
Expression of human telomerase reverse transcriptase gene and protein, and of estrogen and progesterone receptors, in breast tumors: preliminary data from neo-adjuvant chemotherapy.
Expression of human telomerase reverse transcriptase, the catalytic subunit of telomerase, is associated with the development of persistent disease in complete hydatidiform moles.
Expression of human telomerase RNA is an early event of stomach carcinogenesis.
Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.
Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer.
Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors.
Expression of NF-kappaB and human telomerase reverse transcriptase in gastric cancer and precancerous lesions.
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis.
Expression of telomerase activity and oxidative stress in human hepatocellular carcinoma with cirrhosis.
Expression of telomerase activity and telomerase RNA in human soft tissue sarcomas.
Expression of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in gastric adenocarcinomas.
Expression of telomerase activity, telomerase RNA component and telomerase catalytic subunit gene in lung cancer.
Expression of telomerase components in oral keratinocytes and squamous cell carcinomas.
Expression of telomerase genes correlates with telomerase activity in human colorectal carcinogenesis.
Expression of telomerase subunits and localization of telomerase activation in hydatidiform mole.
Expression of telomerase subunits in gastric cancer.
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.
Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer.
Expression of the RNA component of human telomerase (hTR) in prostate cancer, prostatic intraepithelial neoplasia, and normal prostate tissue.
Expression profile of telomerase subunits in human pleural mesothelioma.
Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress.
Extracellular Superoxide Dismutase Induces Mouse Embryonic Fibroblast Proliferative Burst, Growth Arrest, Immortalization, and Consequent In Vivo Tumorigenesis.
Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.
Frequency of TERT promoter mutations in human cancers.
Frequent amplification of the telomerase reverse transcriptase gene in human tumors.
Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer.
FRET investigation toward DNA tetrahedron-based ratiometric analysis of intracellular telomerase activity.
Functional and mechanistic analysis of telomerase: An antitumor drug target.
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Gain of the 3q26 region in cervicovaginal liquid-based pap preparations is associated with squamous intraepithelial lesions and squamous cell carcinoma.
Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells.
Genetic alterations in anaplastic thyroid carcinoma and targeted therapies.
Genetic and epigenetic alterations in multistep carcinogenesis of the stomach.
Genetic and Epigenetic of Medullary Thyroid Cancer
Genetic changes and telomerase activity in human renal cell carcinoma.
Genetic pathways of two types of gastric cancer.
Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome.
Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma.
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.
Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT).
Grainyhead-like 2 as a double-edged sword in development and cancer.
Growth-related signaling regulates activation of telomerase in regenerating hepatocytes.
H. pylori induces a novel NF-?B/Lin28A/let-7a/hTERT axis to promote gastric carcinogenesis.
HCCR-1-interacting molecule "deleted in polyposis 1" plays a tumor-suppressor role in colon carcinogenesis.
Helicobacter pylori infection and carcinogenesis of the stomach.
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.
Hepatitis C virus nonstructural protein NS(3) and telomerase activity.
Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells.
High susceptibility of a human breast epithelial cell type with stem cell characteristics to telomerase activation and immortalization.
High telomerase activity and long telomeres in advanced hepatocellular carcinomas with poor prognosis.
High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis.
Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation.
Histone deacetylase inhibitor AR42 regulates telomerase activity in human glioma cells via an Akt-dependent mechanism.
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells.
Hormones and growth factors regulate telomerase activity in ageing and cancer.
How RNAi machinery enters the world of telomerase.
How will telomeric complex be further contributed to our longevity? - the potential novel biomarkers of telomere complex counteracting both aging and cancer.
HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis.
htert expression correlates with MYC over-expression in human prostate cancer.
hTERT expression in melanocytic lesions: an immunohistochemical study on paraffin-embedded tissue.
hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines.
hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells.
hTERT promoter activity and CpG methylation in HPV-induced carcinogenesis.
hTERT promoter methylation in pituitary adenomas.
hTERT rs2736098 genetic variants and susceptibility of hepatocellular carcinoma in the Chinese population: a case-control study.
Human telomerase and its regulation.
Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor.
Human telomerase catalytic subunit gene re-expression is an early event in oral carcinogenesis.
Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis.
Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues.
Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells.
Human telomerase reverse transcriptase expression in oral carcinogenesis--a preliminary report.
Human telomerase reverse transcriptase is a novel target of Hippo-YAP pathway.
Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ.
Human telomerase reverse transcriptase promoter regulation in normal and malignant human ovarian epithelial cells.
Human telomerase RNA as endogenous control in endometrial tissue.
Human telomerase RNA component (hTERC) gene expression and chromosome 7 ploidy correlate positively with histological grade of cervical intraepithelial neoplasia.
Human Telomerase RNA: Telomerase Component or More?
Human TERT promoter mutations as a prognostic biomarker in glioma.
ICAM-5 (telencephalin) gene expression in head and neck squamous carcinoma tumorigenesis and perineural invasion!
Identification and functional characterization of nuclear mortalin in human carcinogenesis.
Identification of GdRFC1 as a novel regulator of telomerase in Giardia duodenalis.
Immortalization of human osteoblasts by transferring human telomerase reverse transcriptase gene.
Immortalized mouse mammary cells in vivo do not exhibit increased telomerase activity.
Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.
Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths.
Immunohistochemical detection of human telomerase reverse transcriptase in normal mucosa and precancerous lesions of the stomach.
Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas.
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.
Implication of human telomerase reverse transcriptase in cervical carcinogenesis and cancer recurrence.
Implications of telomeres and telomerase in endometrial pathology.
Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.
In silico evaluation of TERT inhibition by anticancer drugs.
In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma.
In situ detection of telomerase enzymatic activity in human hepatocellular carcinogenesis.
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions.
In situ nucleic acid detection of human telomerase in intrahepatic cholangiocarcinoma and its preneoplastic lesion.
In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.
In vivo imaging of human cancer with telomerase-specific replication-selective adenovirus.
Increase in viral load, viral integration, and gain of telomerase genes during uterine cervical carcinogenesis can be simultaneously assessed by the HPV 16/18 MLPA-assay.
Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells.
Increased expression of telomerase RNA component is associated with increased cell proliferation in human astrocytomas.
Increased telomerase activity and absence of p53 mutation in oligoastrocytomas induced by N-ethyl-N-nitrosourea in rats.
Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung.
Increased telomerase activity in mouse skin premalignant progression.
Indole-3-carbinol inhibits telomerase activity and gene expression in prostate cancer cell lines.
Induction of telomerase activity in avian lymphoblastoid cell line transformed by Marek's disease virus, MDCC-MSB1.
Influence of the growth factors PDGF-BB, TGF-beta1 and bFGF on the replicative aging of human articular chondrocytes during in vitro expansion.
Inhibition of cell growth and telomerase activity in osteosarcoma cells by DN-hTERT.
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
Inhibition of human telomerase reverse transcriptase gene expression by BRCA1 in human ovarian cancer cells.
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.
Inhibition of telomerase activity and secretion of prostate specific antigen by silibinin in prostate cancer cells.
Inhibition of telomerase activity by HDV ribozyme in cancers.
Inhibition of telomerase activity by NME2: impact on metastasis suppression?
Inhibition of telomerase enhances apoptosis induced by sodium butyrate via mitochondrial pathway.
Inhibition of telomerase in tumor cells by ribozyme targeting telomerase RNA component.
Inhibition of telomerase induces alternative lengthening of telomeres during human esophageal carcinogenesis.
Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells.
Inhibition of the hTERT promoter by the proto-oncogenic protein TAL1.
Inhibitor of the human telomerase reverse trancriptase (hTERT) gene promoter induces cell apoptosis via a mitochondrial-dependent pathway.
Inhibitory effects of ursodeoxycholic acid on N-methylnitrosourea-induced colon carcinogenesis and colonic mucosal telomerase activity in F344 rats.
Insights into Cdc13 dependent telomere length regulation.
Interferon-alpha repressed telomerase along with G1-accumulation of Daudi cells.
Interleukin 8 is a biomarker of telomerase inhibition in cancer cells.
Involvement of the NFX1-repressor complex in PKC-?-induced repression of hTERT transcription.
Involvement of WRN helicase in immortalization and tumorigenesis by the telomeric crisis pathway (Review).
Irradiation-induced telomerase activity and the risk of lung cancer: a pilot case-control study.
Isolation and expression of the reverse transcriptase component of the Canis familiaris telomerase ribonucleoprotein (dogTERT).
Isothiazolone derivatives selectively inhibit telomerase from human and rat cancer cells in vitro.
JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and post-translationally in ATL cells.
Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation.
Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC.
Lack of correlation of betel nut chewing, tobacco smoking, and alcohol consumption with telomerase activity and the severity of oral cancer.
Large defects of type I allergic response in telomerase reverse transcriptase knockout mice.
Latency and tumorigenesis in Marek's disease.
Leucocyte telomere length, genetic variants at the
Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.
Long telomeres bypass the requirement for telomere maintenance in human tumorigenesis.
Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.
Loss of telomeric DNA during aging may predispose cells to cancer (review).
Malignant transformation of the cultured human normal biliary tract epithelial cells induced by hepatitis C virus core protein.
Mammalian telomerase: catalytic subunit and knockout mice.
Manipulating mouse telomeres: models of tumorigenesis and aging.
Marek's disease: Genetic regulation of gallid herpesvirus 2 infection and latency.
MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene.
Measuring telomerase activity in various human tumors in routine histology and cytology.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
Mechanisms for telomerase gene control in aging cells and tumorigenesis.
Mechanisms of telomerase induction during vascular smooth muscle cell proliferation.
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players.
Mechanixm of Carcinogenesis By RNA Tumor Viruses, I. An RNA-Dependent DNA Polymerase In Murine Sarcoma Viruses.
Melatonin down-regulates hTERT expression induced by either natural estrogens (17beta-estradiol) or metalloestrogens (cadmium) in MCF-7 human breast cancer cells.
miR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame of hTERT.
Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse.
Modulation of telomerase expression and function by miRNAs: Anti-cancer potential.
Molecular analysis of PinX1 in human hepatocellular carcinoma.
Molecular biological observations in gastric cancer.
Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells.
Molecular mechanism of human stomach carcinogenesis implicated in Helicobacter pylori infection.
Molecular mechanisms by which oxidative DNA damage promotes telomerase activity.
Molecular pattern of ductal pancreatic cancer.
Molecular Profiling and Research of Therapeutic Targets.
Molecular targeting of neural cancer stem cells: TTAGGG, you're it!
Mouse models for the study of telomerase.
Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.
Multiple tumor suppressor pathways negatively regulate telomerase.
Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues-A Paradigm Shift in Tissue Regeneration and Evolution.
Mutation of TP53 gene is involved in carcinogenesis of hepatic undifferentiated (embryonal) sarcoma of the adult, in contrast with Wnt or telomerase pathways: an immunohistochemical study of three cases with genomic relation in two cases.
Mutation Profile of Well-Differentiated Thyroid Cancer in Asians.
Mutational analysis defines a minimum level of telomerase activity required for tumourigenic growth of human cells.
Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.
Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma.
Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents.
Ndj1p-dependent epigenetic resetting of telomere size in yeast meiosis.
Neoplastic transformation and cytogenetic changes after Gamma irradiation of human epithelial cells expressing telomerase.
New Directions in the Treatment of Glioblastoma.
Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine.
Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton's lymphoma ascites tumor.
Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis.
Nucleolar localization of TERT is unrelated to telomerase function in human cells.
Oligonucleotides Targeting Telomeres and Telomerase in Cancer.
Overexpression of human telomerase RNA in Helicobacter pylori-infected human gastric mucosa.
Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis.
P53 expression, p53 and Ha-ras mutation and telomerase activation during nitrosamine-mediated hamster pouch carcinogenesis.
Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Persistent human papillomavirus infection and cervical neoplasia.
PES1 is a critical component of telomerase assembly and regulates cellular senescence.
PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis.
Pluripotent nontumorigenic multilineage differentiating stress enduring cells (Muse cells): a seven-year retrospective.
Possible immortalization of Hodgkin and Reed-Sternberg cells: telomerase expression, lengthening of telomere, and inhibition of apoptosis by NF-kappaB expression.
Possible role of telomerase activation in the cancer predisposition of patients with hereditary nonpolyposis colorectal cancers.
Potent antitumoral efficacy of a novel replicative adenovirus CNHK300 targeting telomerase-positive cancer cells.
Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity level.
Presence of telomerase activity with undetectable p16 gene mutation in Malaysian patients with brain tumor.
Prevalence of telomerase activity in human cancer.
Prognostic potential of the telomerase subunit human telomerase reverse transcriptase in tumor tissue and nontumorous mucosa from patients with colorectal carcinoma.
Prognostic relevance of hTERT mRNA expression in ductal adenocarcinoma of the pancreas.
Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis.
Prognostic value of human telomerase reverse transcriptase gene expression in oral carcinogenesis.
Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis.
Proinflammatory cytokine TNF? promotes HPV-associated oral carcinogenesis by increasing cancer stemness.
Prompt activation of telomerase by chemical carcinogens in rats detected with a modified TRAP assay.
Proteomics: the tool to bridge the gap between the facts and fables of telomerase.
Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR.
Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells.
Quantitative assay of telomerase activity in head and neck squamous cell carcinoma and other tissues.
Quantitative assessment of hTERT mRNA expression in dysplastic nodules of HBV-related hepatocarcinogenesis.
Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas.
Raloxifene inhibits estrogen-induced up-regulation of telomerase activity in a human breast cancer cell line.
Real-time PCR hTERT mRNA pattern in tumor core, edge, resection margin, and lymph nodes in laryngeal tumors: relation to proliferative index and impact on prognosis.
Real-time telomerase activity measurements for detection of cancer.
Reappraisal of analysis of the DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis.
Rearrangement of upstream sequences of the hTERT gene during cellular immortalization.
Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas.
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT.
Recurrent epimutations activate gene body promoters in primary glioblastoma.
Regulation of c-MYC transcriptional activity by transforming growth factor-beta 1-stimulated clone 22.
Regulation of telomerase activity by the p53 family member p73.
Regulation of telomerase activity in quiescent immortalized human cells.
Regulation of telomerase and its hTERT messenger in colorectal cancer.
Regulation of telomerase and telomeres: human tumor viruses take control.
Regulation of telomerase by human papillomaviruses.
Regulation of telomerase during human placental differentiation: a role for TGFbeta1.
Regulation of the human catalytic subunit of telomerase (hTERT).
Regulation of the human telomerase reverse transcriptase gene.
Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives.
Relationship Between Serum microRNA155 and Telomerase Expression in Hepatocellular Carcinoma.
Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix.
Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma.
Replication of an adenoviral vector controlled by the human telomerase reverse transcriptase promoter causes tumor-selective tumor lysis.
Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer.
Retinoic acid inhibits telomerase activity and downregulates expression but does not affect splicing of hTERT: correlation with cell growth rate inhibition in an in vitro cervical carcinogenesis/multidrug-resistance model.
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation.
RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells.
Role of DNA methylation and CpG sites in the viral telomerase RNA promoter during Gallid herpesvirus 2 pathogenesis.
Role of GLTSCR2 in the regulation of telomerase activity and chromosome stability.
Role of menin in the regulation of telomerase activity in normal and cancer cells.
Role of telomerase in cell senescence and oncogenesis.
Role of Telomerase in Cervical Lesions as Prognostic Marker: A Comparison Between Immunohistochemistry and FISH.
Semi-quantitative analysis of telomerase activity in exfoliated human urothelial cells and bladder transitional cell carcinoma.
Semiquantitative analysis of telomerase activity in cervical cancer and precancerous lesions.
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells.
Shortened telomere length is demonstrated in T-cell subsets together with a pronounced increased telomerase activity in CD4 positive T cells from blood of patients with mycosis fungoides and parapsoriasis.
ShRNA-mediated BMI-1 gene silencing inhibits gastrointestinal stromal tumor cell telomerase activity and enhances apoptosis.
Signaling on telomerase: a master switch in cell aging and immortalization.
Signaling through estrogen receptors modulates telomerase activity in human prostate cancer.
Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells.
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).
Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging.
Strategies targeting telomerase inhibition.
Successful immortalization of endometrial glandular cells with normal structural and functional characteristics.
Suppression of cell proliferation and telomerase activity in 4-(hydroxyphenyl)retinamide-treated mammary tumors.
Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: regulatory mechanisms.
Survivin enhances telomerase activity via up-regulation of specificity protein 1- and c-Myc-mediated human telomerase reverse transcriptase gene transcription.
Synergistic down-regulation of telomerase activity and hTERT mRNA expression by combination of retinoic acid and GM-CSF in human myeloblastic leukemia ML-1 cells.
Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line.
Synergistic Interaction of Telomerase-Specific Oncolytic Virotherapy and Chemotherapeutic Agents for Human Cancer.
Systematic determination of telomerase activity and telomerase length during the progression of human breast cancer in cell culture models.
Tandem Application of Virtual Screening and NMR Experiments in the Discovery of Brand New DNA Quadruplex Groove Binders.
Targeting telomerase by antisense-based approaches: perspectives for new anti-cancer therapies.
Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis.
Telomerase activates transcription of cyclin D1 gene through the interaction with NOL1.
Telomerase activation and cell proliferation during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.
Telomerase activation and MAPK pathways in regenerating hepatocytes.
Telomerase activation and p53 mutations in urethane-induced A/J mouse lung tumor development.
Telomerase activation cooperates with inactivation of p16 in early head and neck tumorigenesis.
Telomerase activation in cervical neoplasia.
Telomerase activation in colorectal carcinogenesis.
Telomerase activation in in vitro and in vivo cervical carcinogenesis.
Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.
Telomerase activation in neoplastic cell immortalization and tumour progression.
Telomerase activity and Bcl-2 expression in gallbladders of pancreaticobiliary maljunction patients: a preliminary study.
Telomerase activity and clinical progression in chronic lymphoproliferative disorders of B-cell lineage.
Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues.
Telomerase activity and expression of telomerase genes in squamous dysplasia and squamous cell carcinoma of the esophagus.
Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer.
Telomerase activity and genetic alterations in primary breast carcinomas.
Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer.
Telomerase activity and hTERT protein expression in meningiomas: an analysis in vivo versus in vitro.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity and human telomerase reverse transcriptase expression in colorectal carcinoma.
Telomerase activity and human telomerase reverse transcriptase mRNA expression are correlated with clinical aggressiveness in soft tissue tumors.
Telomerase activity and in situ telomerase RNA expression in oral carcinogenesis.
Telomerase activity and lymphovascular invasion in breast cancer.
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
Telomerase activity and oncogenesis in giant cell tumor of bone.
Telomerase activity and prognosis in breast cancer.
Telomerase activity and telomerase catalytic subunit in hepatocellular carcinoma.
Telomerase activity and telomerase reverse transciptase (TERT) expression in ameloblastomas.
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
Telomerase activity and telomere length in lymphocytes from patients with cutaneous T-cell lymphoma.
Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence.
Telomerase activity as a potential marker in preneoplastic bladder lesions.
Telomerase activity as a prognostic factor in colorectal cancer.
Telomerase activity as a tumor marker in Indian women with cervical intraepithelial neoplasia and cervical cancer.
Telomerase activity as an indicator of malignant potential in iodine-nonreactive lesions of the esophagus.
Telomerase activity associated with acquisition of malignancy in human colorectal cancer.
Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer.
Telomerase Activity Detection with Amplification-Free Single Molecule Stochastic Binding Assay.
Telomerase activity during carcinogenesis in the bronchus.
Telomerase activity in benign and malignant human thyroid tissues.
Telomerase activity in cancer as a diagnostic and therapeutic target.
Telomerase activity in cell lines of pediatric soft tissue sarcomas.
Telomerase activity in cervical intraepithelial neoplasia.
Telomerase activity in chronic inflammatory bowel disease.
Telomerase activity in condyloma acuminatum tissue with different HPV types.
Telomerase activity in ductal carcinoma in situ of the breast.
Telomerase activity in esophageal squamous cell carcinoma and lesions unstained with Lugol's solution.
Telomerase Activity in Gastric Adenocarcinomas: Frozen Tissues Versus Methacarn-fixed Paraffin-embedded Tissues.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in gastric cancer.
Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.
Telomerase activity in high-grade cervical lesions is associated with allelic imbalance at 6Q14-22.
Telomerase activity in human bladder cancer.
Telomerase activity in human bladder tumors and bladder washing specimens.
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.
Telomerase activity in human laryngeal squamous cell carcinomas.
Telomerase activity in human pleural mesothelioma.
Telomerase activity in human proliferative breast lesions.
Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis.
Telomerase activity in Indian patients with carcinomas of the aerodigestive tract.
Telomerase activity in juxtacortical and conventional high-grade osteosarcomas: correlation with grade, proliferative activity and clinical response to chemotherapy.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome.
Telomerase activity in microdissected human gliomas.
Telomerase activity in neuroendocrine tumors.
Telomerase activity in normal and malignant murine tissues.
Telomerase activity in oral and maxillofacial tumors.
Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma.
Telomerase activity in oral squamous cell carcinoma.
Telomerase activity in ovarian tumors.
Telomerase activity in patients with transitional cell carcinoma: a preliminary study.
Telomerase activity in pituitary adenomas: significance of telomerase expression in predicting pituitary adenoma recurrence.
Telomerase activity in plasma cell dyscrasias.
Telomerase activity in pleural malignant mesotheliomas.
Telomerase activity in precancerous hepatic nodules.
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Telomerase activity in primary and secondary glioblastomas multiforme as a novel molecular tumor marker.
Telomerase activity in prognostic histopathologic features of melanoma.
Telomerase activity in proximal and distal gastric neoplastic and preneoplastic lesions using immunohistochemical detection of hTERT.
Telomerase activity in sex cord-stromal tumors of the ovary.
Telomerase activity in the human breast.
Telomerase activity in thymomas and mammary gland adenocarcinomas induced by polyoma virus in AKR mice.
Telomerase activity is detected in pancreatic cancer but not in benign tumors.
Telomerase activity is frequently found in metaplastic and malignant human nasopharyngeal tissues.
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase.
Telomerase activity is upregulated in laryngeal squamous cell carcinoma.
Telomerase activity modulation in the prevention of prostate cancer.
Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues.
Telomerase activity of the Lugol-stained and -unstained squamous epithelia in the process of oesophageal carcinogenesis.
Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review.
Telomerase activity: a biomarker of cell proliferation, not malignant transformation.
Telomerase and cancer stem cells.
Telomerase and human tumorigenesis.
Telomerase and telomere length in normal and malignant human endometrium as prognostic markers.
Telomerase and telomeres in aging theory and chronographic aging theory (Review).
Telomerase and the process of cervical carcinogenesis.
Telomerase and tumorigenesis.
Telomerase as a growth-promoting factor.
Telomerase as a tumor marker in diagnosis of prostatic intraepithelial neoplasia and prostate cancer.
Telomerase catalytic subunit in laryngeal carcinogenesis--an immunohistochemical study.
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism.
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene.
Telomerase Dysfunction in the Tumorigenesis of Genetic Disorders.
Telomerase elevation in pancreatic ductal carcinoma compared to nonmalignant pathological states.
Telomerase expression in B-cell chronic lymphocytic leukemia predicts survival and delineates subgroups of patients with the same igVH mutation status and different outcome.
Telomerase expression in benign and malignant skin neoplasms: comparison of three major subunits.
Telomerase expression in gliomas including the nonastrocytic tumors.
Telomerase expression in lung preneoplasia and neoplasia.
Telomerase expression in sebaceous carcinoma of the eyelid.
Telomerase expression in uveal melanoma.
Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene.
Telomerase hTR and hTRT gene expression in oral precancerous lesions and squamous cell carcinomas.
Telomerase in cancer: clinical applications.
Telomerase in cutaneous carcinogenesis.
Telomerase in gynecologic cancers.
Telomerase in hepatocellular carcinogenesis.
Telomerase in human tumors: molecular diagnosis and clinical significance.
Telomerase in intracranial meningiomas.
Telomerase in the ovary.
Telomerase in urological malignancy.
Telomerase Induction in HPV Infection and Oncogenesis.
Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cells.
Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT.
Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions.
Telomerase is not an oncogene.
Telomerase is not required for experimental tumorigenesis of human and bovine adrenocortical cells.
Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells.
Telomerase is upregulated in irreversible preneoplastic lesions during bladder carcinogenesis in rats.
Telomerase Mechanism of Telomere Synthesis.
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation.
Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells.
Telomerase reactivation is an early event in laryngeal carcinogenesis.
Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity.
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.
Telomerase Regulation: A Role for Epigenetics.
Telomerase reverse transcriptase (TERT) is a novel target of Wnt/?-catenin pathway in human cancer.
Telomerase reverse transcriptase (TERT) promoter mutations in primary adenocarcinoma of bladder and urothelial carcinoma with glandular differentiation: pathogenesis and diagnostic implications.
Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activity.
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence.
Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections.
Telomerase reverse transcriptase promoter mutation in tumorigenesis of bladder cancer: Evolutionary trajectory by algorithmic inference from cross-sectional data.
Telomerase reverse transcriptase regulates the expression of a key cell cycle regulator, cyclin D1.
Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres.
Telomerase RNA expression during progression of gastric cancer.
Telomerase, cervical cancer, and human papillomavirus.
Telomerase, hTERT and splice variants in Barrett's oesophagus and oesophageal adenocarcinoma.
Telomerase, immortality and cancer.
Telomerase, p53 and human papillomavirus infection in the uterine cervix.
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.
Telomerase-specific oncolytic virotherapy for human cancer with the hTERT promoter.
Telomerase-specific replication-selective virotherapy for human cancer.
Telomerase-Specific T-Cell Immunity in Breast Cancer: Effect of Vaccination on Tumor Immunosurveillance.
Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex.
Telomerase: is it the future diagnostic and prognostic tool in human cancer?
Telomerase: Key regulator of inflammation and cancer.
Telomerase: not just for the elongation of telomeres.
Telomere and telomerase in oncology.
Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix.
Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.
Telomere DNA damage signaling regulates cancer stem cell evolution, epithelial mesenchymal transition, and metastasis.
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
Telomere length analysis in residents of a community exposed to arsenic.
Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk.
Telomere length and hTERT expression in patients with colorectal carcinoma.
Telomere length and telomerase activity in carcinogenesis of the stomach.
Telomere length and telomerase expression in atypical adenomatous hyperplasia and small bronchioloalveolar carcinoma of the lung.
Telomere length in Chernobyl accident recovery workers in the late period after the disaster.
Telomere length is related to alternative splice patterns of telomerase in thyroid tumors.
Telomere length of tumor tissues and survival in patients with early stage non-small cell lung cancer.
Telomere Maintenance and DNA Damage Responses during Lung Carcinogenesis.
Telomere maintenance and tumorigenesis: an "ALT"ernative road.
Telomere maintenance in childhood primitive neuroectodermal brain tumors.
Telomere maintenance in sarcomas.
Telomere shortening and expression of TRF1 and TRF2 in uterine leiomyoma.
Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991.
Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas.
Telomere shortening and telomerase reactivation in dysplastic nodules of human hepatocarcinogenesis.
Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesions.
Telomere stability and carcinogenesis: an off-again, on-again relationship.
Telomere structure and shortening in telomerase-deficient Trypanosoma brucei.
Telomere structure and telomerase expression during mouse development and tumorigenesis.
Telomere Terminal G/C Strand Synthesis: Measuring Telomerase Action and C-Rich Fill-In.
Telomere, telomerase, tumorigenesis and therapy: an overview.
Telomeres and telomerase biology in vertebrates: progress towards a non-human model for replicative senescence and ageing.
Telomeres and Telomerase During Human Papillomavirus-Induced Carcinogenesis.
Telomeres and telomerase in adrenocortical tissue maintenance, carcinogenesis and aging.
Telomeres and telomerase in aging, regeneration and cancer.
Telomeres and telomerase in cancer stem cells.
Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.
Telomeres and telomerase in oncogenesis.
Telomeres and telomerase in renal health.
Telomeres and Telomerase in the Development of Liver Cancer.
Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.
Telomeres and telomerase influence the course of human diseases, aging and carcinogenesis.
Telomeres and telomerase: a dual role in hepatocarcinogenesis.
Telomeres and telomerase: a modern fountain of youth?
Telomeres and telomerase: pharmacological targets for new anticancer strategies?
Telomeres and Telomerase: Role in Marek's Disease Virus Pathogenesis, Integration and Tumorigenesis.
Telomeres and telomere dynamics: relevance to cancers of the GI tract.
Telomeres in Plants and Humans: Not So Different, Not So Similar.
TERT Gene rs2736100 and rs2736098 Polymorphisms are Associated with Increased Cancer Risk: A Meta-Analysis.
TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer.
TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker.
TERT promoter mutation in adult granulosa cell tumor of the ovary.
TERT promoter mutations and gene amplification: promoting TERT expression in Merkel cell carcinoma.
TERT promoter mutations and their correlation with BRAF and RAS mutations in a consecutive cohort of 145 thyroid cancer cases.
TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications.
The ?-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype.
The absence of up-regulation of telomerase activity during regeneration after partial hepatectomy in hepatitis B virus X gene transgenic mice.
The association between telomerase, histopathological parameters, and KI-67 expression in breast cancer.
The clinical implications of telomerase activity in upper tract urothelial cancer and washings.
The expression of hTERT mRNA and cellular immunity in gastric cancer and precancerosis.
The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas.
The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter.
The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation.
The identification of two regulatory ESCC susceptibility genetic variants in the TERT-CLPTM1L loci.
The implications of telomerase biochemistry for human disease.
The influence of reactivation of the telomerase in tumour tissue on the prognosis of squamous cell carcinomas in the head and neck.
The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells.
The interaction of telomere DNA G-quadruplex with three bis-benzyltetrahydroisoquinoline alkaloids.
The many faces of telomerase: emerging extratelomeric effects.
The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis.
The multistage process of carcinogenesis in human esophageal epithelial cells induced by human papillomavirus.
The papillomavirus E6 proteins.
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor.
The regulation of telomerase in oncogenesis.
The Role of Alternative Lengthening of Telomeres Mechanism in Cancer: Translational and Therapeutic Implications.
The role of interferon-gamma and vitamin-A in modulating telomerase activity in breast cancer patients.
The role of telomerase activation in the regulation of vascular smooth muscle cell proliferation.
The role of telomeres and telomerase complex in haematological neoplasia: the length of telomeres as a marker of carcinogenesis and prognosis of disease.
The role of telomeres and telomerase in cirrhosis and liver cancer.
The role of telomeres in stem cells and cancer.
The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignancies.
The scaffold protein WRAP53? orchestrates the ubiquitin response critical for DNA double-strand break repair.
The secrets of telomerase: Retrospective analysis and future prospects.
The significance of telomerase activation and cellular immortalization in human cancer.
The tea polyphenol, (-)-epigallocatechin gallate effects on growth, apoptosis, and telomerase activity in cervical cell lines.
The telomerase activities in several organs and strains of rats with ageing.
The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
Therapeutic Targeting of Telomerase.
Three molecular determinants of malignant conversion and their potential as therapeutic targets.
Transcriptional activation of hTERT, the catalytic subunit of telomerase, by NFAT.
Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers.
Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line.
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts.
TRF2 inhibition promotes anchorage-independent growth of telomerase-positive human fibroblasts.
Triptolide inhibits human telomerase reverse transcriptase by downregulating translation factors SP1 and c-Myc in Epstein-Barr virus-positive B lymphocytes.
Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells.
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization.
Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers.
Understanding TERT Promoter Mutations: a Common Path to Immortality.
Up-regulation of human telomerase catalytic subunit during gastric carcinogenesis.
Up-regulation of telomerase activity in Herpesvirus saimiri immortalized human T-lymphocytes.
Up-regulation of telomerase activity in human lymphocytes.
Up-regulation of telomerase activity in human pancreatic cancer cells after exposure to etoposide.
Upregulated human telomerase reverse transcriptase (hTERT) expression is associated with spinal chordoma growth, invasion and poor prognosis.
Upregulation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells.
Upstream stimulatory factor (USF) as a transcriptional suppressor of human telomerase reverse transcriptase (hTERT) in oral cancer cells.
Use of hTERT and HPV E6/E7 mRNA RT-qPCR TaqMan Assays in Combination for Diagnosing High-Grade Cervical Lesions and Malignant Tumors.
Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells.
Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.
Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes.
Value of endoscopic methylene blue and Lugol's iodine double staining and detection of GST-Pi and telomerase in the early diagnosis of esophageal carcinoma.
Variation at the TERT locus and predisposition for cancer.
Vertebrate marine species as model systems for studying telomeres and telomerase.
Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development.
[1997, a good year for telomerase?]
[Aging or tumor: the crosstalk between telomerase and p53]
[Changes of alternative splicing variants of human telomerase reverse transcriptase during gastric carcinogenesis]
[Clinical Application and Challenges of Telomere and Telomerase Research ?in Lung Cancer].
[Clinical significance of telomerase activity in lung cancer.]
[Correlation of hTERT expression to maspin and bFGF expression and their significance in glioma]
[Detection of telomerase activity by semi-quantitative and in situ assays and quantification of hTERT expression in bladder carcinomas]
[Detection of telomerase activity in bronchoscopic brush-off samples in patients with lung cancer]
[Detection of telomerase activity in human lung cancer.]
[Diagnotic value of the combined determination of telomerase activity in induced sputum, pleural effusion and fiberobronchoscopic biopsy samples in lung cancer]
[Effect of hepatitis C virus nonstructural protein NS3 on telomerase activity]
[Effect of telomerase on ginsenoside Rh2-induced differentiation of hepatocarcinoma cell line SMMC-7721.]
[Effects of matrine on the growth inhibition, c-myc and hTERT protein expression in human adenocarcinoma lung cancer cell line A549.]
[Effects of telomerase on cell cycle regulation and tumorigenesis]
[Expression and significance of telomerase reverse transcriptase and its regulators in non-small cell lung carcinoma]
[Expression of telomerase activity and c-myc and stimulatory protein 1 in human ameloblastoma]
[Expression of telomerase activity in human lung cancer.]
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
[Expressions of h-TERT, c-myc, PCNA and cell apoptosis in liver carcinogenesis]
[Genetic alterations in stomach cancer]
[Genic alterations in oral and head and neck squamous cell carcinomas: analysis of international literature]
[Identification of telomerase activity in the experimental carcinogenesis of oral cavity]
[Inhibitory effect of antisense human telomerase reverse transcriptase(hTERT) on telomerase activity of human pulmonary giant cell carcinoma cell line(PLA-801D)]
[Inhibitory effect of yiqijiedu powder to telomerase and telomerase RNA in nasopharyngeal tumorigenesis of rats]
[Oncolytic virotherapy for human solid tumors]
[Preliminary study on the alternative splicing pattern of human telomerase reverse transcriptase gene during gastric carcinogenesis.]
[Profile of telomerase and telomerase RNA expression in nasopharyngeal carcinogenesis of rats induced by N, N'dinitrosopiperazine (DNP)]
[Prognostic and diagnostic value of telomerase in the head and neck cancer]
[Progress in telomerase and the inhibitors]
[Quantitative detection of telomerase activity and its association with clinicopathological characteristics in breast cancer]
[Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck]
[Relationship among telomerase activity, expression of human telomerase reverse transcriptase (hTERT), and expression of c-myc in acute leukemia]
[Research on expression of human papillomavirus type 16 and telomerase in oral lesions]
[Study and detection of telomerase activity in oral squamous cell carcinomas and precancerous lesions]
[Study on the correlation between the different papillomavirus type and telomerase in cervical cancer]
[Study on the relationship between telomerase gene and telomerase activity in lung cancer tissue.]
[Telomerase activity and genomic instability in colorectal cancers]
[Telomerase activity in cervical cancer and its precursor lesion]
[Telomerase activity in cervical intraepithelial neoplasia]
[Telomerase activity in colorectal cancer--a semi-quantitative procedure]
[Telomerase activity in human head and neck squamous cell carcinoma and adjacent tissues]
[Telomerase activity in human primary lung caner.]
[Telomerase activity in oral squamous cell carcinoma and leukoplakia]
[Telomerase activity in rat tongue carcinogenesis]
[Telomerase expression in colorectal tubular adenoma determined by immunohistochemical staining]
[Telomerase expression in tarsal gland carcinoma]
[Telomerase hTRT mRNA expression in oral squamous cell carcinogenesis]
[Telomerase in diseases of the digestive system]
[Telomerase in tumors: facts and perspectives]
[Telomerase inhibitor]
[Telomerase, cell immortality and cancer]
[Telomerase]
[Telomere and cancer: what's more at the end?]
[Telomere length and telomerase activity in intestinal metaplasia, adenoma and well differentiated adenocarcinoma of the stomach]
[Telomeres and telomerase]
[The effect of hepatitis B virus X gene transfection on expression of human telomerase reverse transcriptase mRNA in human bile duct carcinoma cell lines]
[The effect of shRNA targeting hTERT on telomerase and the expression of PCNA and Caspase-3 in nasopharyngeal carcinoma cells]
[The experimental study on telomerase activity and expression of p53 and c-myc genes in tongue cancer]
[The expression and significance of human telomerase reverse transcriptase protein and gene in bile duct carcinomas and their adjacent tissues]
[The function of Aurora A and its role in the development of liver cancer].
[The role of telomerase for pancreatic carcinogenesis in human and hamster]
[The significance of telomerase activity in patients with gastric cancer]
[The study on the role of telomerase activity in human nasopharyngeal carcinoma]
[Theranostic application of telomerase-specific oncolytic adenovirus for human cancer]
Carcinoid Tumor
Differential expression of telomerase activity in neuroendocrine lung tumours: correlation with gene product immunophenotyping.
hTR repressor-related gene on human chromosome 10p15.1.
Lack of telomerase activity in lung carcinoids is dependent on human telomerase reverse transcriptase transcription and alternative splicing and is associated with long telomeres.
Telomerase activity in pulmonary neuroendocrine tumors: correlation with histologic subtype (MS-0060).
Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Carcinoma
3q26 (hTERC) gain studied by fluorescence in situ hybridization as a persistence-progression indicator in low-grade squamous intraepithelial lesion cases.
4-Hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
67-kDa laminin receptor in human laryngeal squamous cell carcinoma.
?-Elemene inhibits the proliferation of esophageal squamous cell carcinoma by regulating long noncoding RNA-mediated inhibition of hTERT expression.
A case of gallbladder carcinoma diagnosed preoperatively by the detection of human telomerase reverse transcriptase mRNA in endoscopically obtained gallbladder bile.
A comparison of BTA stat, hemoglobin dipstick, telomerase and Vysis UroVysion assays for the detection of urothelial carcinoma in urine.
A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity.
A highly sensitive and quantitative telomerase activity assay with pancreatic juice is useful for diagnosis of pancreatic carcinoma without problems due to polymerase chain reaction inhibitors: analysis of 100 samples of pancreatic juice from consecutive patients.
A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma.
A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.
A novel tumor-specific gene therapy for bladder cancer.
A prospective evaluation of the diagnostic and potential prognostic utility of urinary human telomerase reverse transcriptase mRNA in patients with bladder cancer.
A Telomerase Responsive DNA-icosahedron for Precise Delivery of Platinum-nanodrug to Cisplatin-resistance Cancer.
Absence of correlation between telomerase activity and hepatic neoplasia in B6C3F1 mice.
Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.
Acquired cellular resistance to flavopiridol in a human colon carcinoma cell line involves up-regulation of the telomerase catalytic subunit and telomere elongation. Sensitivity of resistant cells to combination treatment with a telomerase inhibitor.
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Advantages of assaying telomerase activity in ascites for diagnosis of digestive tract malignancies.
Allelotype and loss of heterozygosity around the L-myc gene locus in primary lung cancers.
AlphaCP1 mediates stabilization of hTERT mRNA by autocrine human growth hormone.
Alternative lengthening of telomeres frequently occurs in mismatch repair system-deficient gastric carcinoma.
Alternative splicing of calretinin mRNA leads to different forms of calretinin.
Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells.
Amplification of the human telomerase gene in liquid-based preparations is associated with cervical dysplasia and carcinoma.
Amplification of the telomerase reverse transcriptase (hTERT) gene in cervical carcinomas.
Amplification of the telomerase RNA component gene as a new genetic marker for disease progression and prognosis in esophageal squamous cell carcinoma.
Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer.
An institutional experience evaluating hTERT immunostaining in 100 consecutive ThinPrep urine specimens.
An ultra-sensitive colorimetric assay for reliable visual detection of telomerase activity.
Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors, and invasive carcinomas.
Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma.
Analysis of telomeric repeats and telomerase activity in human colon carcinoma cells with gene amplification.
Androgen ablation therapy for prostate carcinoma suppresses the immunoreactive telomerase subunit hTERT.
Antagonistic Interactions Between Gemcitabine and 5-Fluorouracil in the Human Pancreatic Carcinoma Cell Line Capan-2.
Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro.
Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells.
Antitumor Activity of Small Double-Stranded Oligodeoxynucleotides Targeting Telomerase RNA in Malignant Melanoma Cells.
Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines.
Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression.
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Association between clincopathological characteristics and hTERT expression as well as telomere length in ameloblastoma.
Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology.
Association of p53 gene mutation and telomerase activity in resectable non-small cell lung cancer.
Association of telomerase expression with successful heterotransplantation of lung cancer.
Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells.
Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells.
Augmented telomerase activity, reduced telomere length and the presence of alternative lengthening of telomere in renal cell carcinoma: Plausible predictive and diagnostic markers.
Autocatalytic caspase-3 driven by human telomerase reverse transcriptase promoter suppresses human ovarian carcinoma growth in vitro and in mice.
Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells.
Azacitidine, as a DNMT inhibitor decreases hTERT gene expression and telomerase activity more effective compared with HDAC inhibitor in human Head and neck squamous cell carcinoma cell lines.
BCG effects on telomerase activity in bladder cancer cell lines.
Biochemical and electron microscopical evidence for the presence of oncorna viruses in spleen tissue from two patients with haematological malignancies.
Biological behavior of keratoacanthoma and squamous cell carcinoma: telomerase activity and COX-2 as potential markers.
Biological features of bronchial squamous dysplasia followed up by autofluorescence bronchoscopy.
Biological significance of PinX1 telomerase inhibitor in esophageal carcinoma treatment.
Biological significance of TERT promoter mutation in papillary urothelial neoplasm of low malignant potential.
Biology of ovarian cancer.
Bowen's disease with high telomerase activity.
Bronchogenic and alveologenic tumors in mice induced by N-nitrosopiperidine.
C2-O-sLeX glycoproteins are E-selectin ligands that regulate invasion of human colon and hepatic carcinoma cells.
Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.
Cell cycle-regulated trafficking of human telomerase to telomeres.
Cervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity.
Cervical intraepithelial neoplasia: Telomerase activity and splice pattern of hTERT mRNA.
Change in telomerase activity during human colorectal carcinogenesis.
Change of telomerase activity in peripheral blood of patients with head and neck squamous cell carcinoma pre and post curative treatment.
Change of telomerase activity in peripheral whole blood of head and neck squamous cell carcinoma patients before and after surgery: a pilot study.
Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines.
Changes in telomerase activity, expression and splicing in response to differentiation of normal and carcinoma colon cells.
Characterization of plasminogen system on rat yolk sac carcinoma (L2) cells.
Chromosome in situ hybridisation, Ki-67, and telomerase immunocytochemistry in liquid based cervical cytology.
Circadian telomerase activity and DNA synthesis for timing peptide administration.
Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer.
Clinical application of human telomerase reverse transcriptase gene expression in thyroid follicular tumors by fine-needle aspirations using in situ hybridization.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer.
Clinical significance of telomerase activity in basal cell carcinomas and in tumour-free surgical margins.
Clinical significance of telomerase activity in gastric carcinoma and peritoneal dissemination.
Clinical significance of telomerase activity in peripheral blood of patients with esophageal squamous cell carcinoma.
Clinical significance of telomerase activity in the non-cancerous epithelial region of oesophageal squamous cell carcinoma.
Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus.
Clonal expansion and HPV-induced immortalization are early molecular alterations in cervical carcinogenesis.
Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy.
Coexistence of BRAF V600E and TERT Promoter Mutations in Low-grade Serous Carcinoma of Ovary Recurring as Carcinosarcoma in a Lymph Node: Report of a Case.
Combination of assay of human telomerase reverse transcriptase mRNA and cytology using bile obtained by endoscopic transpapillary catheterization into the gallbladder for diagnosis of gallbladder carcinoma.
Combined assay of CYFRA21-1, telomerase and vascular endothelial growth factor in the detection of bladder transitional cell carcinoma.
Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours.
Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma.
Comparison of human telomerase reverse transcriptase messenger RNA and telomerase activity as urine markers for diagnosis of bladder carcinoma.
Comparison of human telomerase RNA and telomerase activity in urine for diagnosis of bladder cancer.
Comparison of screening methods in the detection of bladder cancer.
Comparison of telomerase activity in bladder carcinoma and exfoliated cells collected in urine and bladder washings, using a quantitative assay.
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma.
Correlation between morphology and telomerase activity in cells from exfoliative lung cytologic specimens.
Correlation of dyskerin expression with active proliferation independent of telomerase.
Correlation of expression of CD44 isoforms and E-cadherin with differentiation in human urothelial cell lines and transitional cell carcinoma.
Correlation of telomerase activity, clinical prognosis and therapy in oral carcinogenesis.
Correlation of the expression of telomerase RNA with risk factors for recurrence of sebaceous gland carcinoma.
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.
Decrease of telomeres and increase of interstitial telomeric sites in chromosomes of short-term cultured gastric carcinoma cells detected by fluorescence in situ hybridization.
Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors.
Demonstration of constant upregulation of the telomerase RNA component in human gastric carcinomas using in situ hybridization.
Demonstration of human telomerase reverse transcriptase by in situ hybridization in lung carcinoma.
Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization.
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Detection of circulating carcinoma cells by telomerase activity.
Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal Pap smears.
Detection of HPV E7 Oncoviral Protein in Cervical Lesions by a New Antibody.
Detection of hTERC and c-MYC genes in cervical epithelial exfoliated cells for cervical cancer screening.
Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformation.
Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination.
Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy.
Detection of telomerase activity in biopsy specimens for diagnosis of biliary tract cancers.
Detection of telomerase activity in cultured cells and tumor tissue of lung carcinoma by modified telomeric repeat amplification protocol.
Detection of telomerase activity in esophageal squamous cell carcinoma and normal esophageal epithelium.
Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications.
Detection of telomerase activity in exfoliated cancer cells obtained from bile.
Detection of telomerase activity in human carcinomas using a trap-ELISA method: correlation with hTR and hTERT expression.
Detection of telomerase activity in human prostate: a diagnostic marker for prostatic cancer?
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Detection of telomerase activity in oral lesions.
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Detection of telomerase activity in patients with pancreatic cancer.
Detection of telomerase activity in saliva from oral squamous cell carcinoma patients.
Detection of telomerase reverse transcriptase mRNA in biopsy specimens and bile for diagnosis of biliary tract cancers.
Detection of telomerase status by semiquantitative and in situ assays, and by real-time reverse transcription-polymerase chain reaction (telomerase reverse transcriptase) assay in bladder carcinomas.
Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data.
Determination of telomerase activity for differential analysis of multifocal renal cell carcinomas.
Determination of telomerase activity in multifocal renal cell carcinoma.
Determination of telomerase activity in squamous cell carcinoma of the penis.
Determination of the activity of telomerase in cancer cells by using BSA-protected gold nanoclusters as a fluorescent probe.
Diagnosis of esophagogastric tumors.
Diagnostic value of telomerase expression in breast fine-needle aspiration biopsies.
Different amplification patterns of the human telomerase RNA gene in invasive cervical carcinomas and cervical intraepithelial neoplasia grade III.
Differential expression of full-length telomerase reverse transcriptase mRNA and telomerase activity between normal and malignant renal tissues.
Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions.
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours.
Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma, and glioma cells in culture.
Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis.
Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors.
Differing Expression of Cytokines and Tumor Markers in Combined Pulmonary Fibrosis and Emphysema Compared to Emphysema and Pulmonary Fibrosis.
Dissemination of cancer cells into circulation occurs by incisional biopsy of oral squamous cell carcinoma.
Distinct profiles of TERT promoter mutations and telomerase expression in head and neck cancer and cervical carcinoma.
Divalent hammerhead ribozyme targeting template region of human telomerase RNA has potent cleavage activity, but less inhibitory activity on telomerase.
Down-regulation of cyclooxygenase-2 and telomerase activity by beta-lapachone in human prostate carcinoma cells.
Dyskeratosis Congenita and Oral Cavity Squamous Cell Carcinoma: Report of a Case and Literature Review.
Early diagnosis for colorectal cancer in China.
Ectopic expression of wnt-5a in human renal cell carcinoma cells suppresses in vitro growth and telomerase activity.
Effect of all-trans retinoic acid on telomerase activity in ovarian cancer cells.
Effect of antisense human telomerase RNA on malignant phenotypes of gastric carcinoma.
Effect of silencing key proteins in telomerase mechanism and alternative lengthening of telomeres mechanism in laryngeal cancer cells.
Effect of VEGF, P53 and telomerase on angiogenesis of gastric carcinoma tissue.
Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.
Effects of telomerase activity on carcinogenesis and survival in laryngeal carcinoma.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
EGFR Tyrosine Kinase Inhibitor Pelitinib Regulates Radiation-Induced p65-Dependent Telomerase Activation in Squamous Cell Carcinoma.
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase.
Emerging immunotherapeutic strategies targeting telomerases in genitourinary tumors.
Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia.
Epigenetic perturbation driving asleep telomerase reverse transcriptase: Possible therapeutic avenues in carcinoma.
Erucin and Benzyl Isothiocyanate Suppress Growth of Late Stage Primary Human Ovarian Carcinoma Cells and Telomerase Activity In Vitro.
Evaluation of an in vitro telomeric repeat amplification protocol assay to detect telomerase activity in canine urine.
Evaluation of combined telomerase and c-myc expression in non-small cell lung carcinomas using tissue microarrays and computerized image analysis.
Evaluation of Sienna Cancer Diagnostics hTERT Antibody on 500 Consecutive Urinary Tract Specimens.
Evaluation of telomerase in non-melanoma skin cancer.
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
Evidence for elevated telomerase activity in small cell carcinoma of the bladder.
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
Ex vivo expanded telomerase-specific T cells are effective in an orthotopic mouse model for pancreatic adenocarcinoma.
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.
Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma.
Expression of cancer testis antigens in head and neck squamous cell carcinomas.
Expression of Epstein-Barr virus in thyroid carcinoma correlates with tumor progression.
Expression of hTERT in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma - an Immunohistochemical Analysis.
Expression of human telomerase reverse transcriptase (hTERT) protein is significantly associated with the progression, recurrence and prognosis of oral squamous cell carcinoma in Taiwan.
Expression of human telomerase reverse transcriptase in vulvar intraepithelial neoplasia and squamous cell carcinoma: an immunohistochemical study with survivin and p53.
Expression of human telomerase reverse transcriptase protein in oral epithelial dysplasia and oral squamous cell carcinoma: An immunohistochemical study.
Expression of human telomerase reverse transcriptase, Survivin, DD3 and PCGEM1 messenger RNA in archival prostate carcinoma tissue.
Expression of human telomerase RNA is an early event of stomach carcinogenesis.
Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas.
Expression of telomerase catalytic component, telomerase reverse transcriptase, in human gastric carcinomas.
Expression of telomerase catalytic subunit (hTERT) mRNA does not predict survival in patients with transitional cell carcinoma of the upper urinary tract.
Expression of telomerase components in oral keratinocytes and squamous cell carcinomas.
Expression of telomerase genes in thyroid carcinoma.
Expression of telomerase mRNA component (hTR) in transitional cell carcinoma of the upper urinary tract.
Expression of telomerase reverse transcriptase in peripheral T-cell lymphoma.
Expression of telomerase subunits in normal and neoplastic prostate epithelial cells isolated by laser capture microdissection.
Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas.
Expression of thrombospondin-1 is correlated with microvessel density in gastric carcinoma.
Expression of VEGF, HGF, IL-6, IL-8, MMP-9, Telomerase in Peripheral Blood of Patients with Head and Neck Squamous Cell Carcinoma.
Expression pattern of telomerase reverse transcriptase in rectal carcinoma predicts tumor radiosensitivity, local recurrence and disease-free survival.
Focal intratumoral heterogeneity for telomerase activity in human prostate cancer.
Frequent high telomerase reverse transcriptase expression in primary oral squamous cell carcinoma.
Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.
Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4.
Gain of Chromosomal Region 3q26 as a Prognostic Biomarker for High-Grade Cervical Intraepithelial Neoplasia: Literature Overview and Pilot Study.
Gain of the human telomerase RNA gene TERC at 3q26 is strongly associated with cervical intraepithelial neoplasia and carcinoma.
Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells.
Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter.
Genes associated with telomerase activity levels in esophageal carcinoma cell lines.
Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells.
Genetic changes and telomerase activity in human renal cell carcinoma.
Genetic control of telomerase and replicative senescence in human and rodent cells.
Genomic amplification of hTERC in paraffin-embedded tissues of cervical intraepithelial neoplasia and invasive cancer.
Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer.
Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity.
High expression of circadian gene mPer2 diminishes radiosensitivity of tumor cells.
High expression of human telomerase reverse transcriptase in high-grade intraepithelial neoplasia and carcinoma of uterine cervix and its correlation with human papillomavirus infection.
High levels of telomere dysfunction bestow a selective disadvantage during the progression of human oral squamous cell carcinoma.
High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma.
High telomerase activity correlates with the stabilities of genome and DNA ploidy in renal cell carcinoma.
Histological markers of risk and the role of high-grade prostatic intraepithelial neoplasia.
hTERT expression in sporadic renal cell carcinomas.
hTERT is a critical determinant of telomerase activity in renal-cell carcinoma.
hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression.
hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells.
Human epithelial cell immortalization as a step in carcinogenesis.
Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma.
Human squamous cell carcinomas lose a mortality gene from chromosome 6q14.3 to q15.
Human telomerase and alpha-methylacyl-coenzyme A racemase in prostatic carcinoma. A comparative immunohistochemical study.
Human telomerase reverse transcriptase expression and its clinical significance in laryngeal squamous cell carcinoma.
Human telomerase reverse transcriptase expression in colorectal tumors: correlations with immunohistochemical expression and clinicopathologic features.
Human telomerase reverse transcriptase is a promising target for cancer inhibition in squamous cell carcinomas.
Human telomerase reverse transcriptase mRNA expression assessed by real-time reverse transcription polymerase chain reaction predicts chemosensitivity in patients with ovarian carcinoma.
Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma.
Human telomerase reverse transcriptase regulates cyclin D1 and G1/S phase transition in laryngeal squamous carcinoma.
Human telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment.
Human telomerase RNA component (hTERC) gene amplification detected by FISH in precancerous lesions and carcinoma of the larynx.
Human telomerase RNA expression and MIB-1 (Ki-67) proliferation index distinguish hemangioblastomas from metastatic renal cell carcinomas.
Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.
Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma: tumor size and lymph node status remain the most important prognostic features.
Immunoexpression and prognostic role of hTERT and cyclin D1 in urothelial carcinoma.
Immunohistochemical and molecular study of radiation-induced multiple meningiomas with pleural and pulmonary metastasis.
Immunohistochemical detection of human telomerase reverse transcriptase (hTERT) and c-kit in serous ovarian carcinoma: a clinicopathologic study.
Immunohistochemical detection of human telomerase reverse transcriptase in normal mucosa and precancerous lesions of the stomach.
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Immunohistochemical expression of p53, p16 and hTERT in oral squamous cell carcinoma and potentially malignant disorders.
Immunohistochemical expression of proliferative markers in renal cell carcinoma.
Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.
Improvement in detecting telomerase activity using silica-based resin treatment: An experience of urine in bladder carcinoma.
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions.
In vitro modulation of telomerase activity, telomere length and cell cycle in MKN45 cells by verbascoside.
Increased phosphorylation of AKT in high-risk gastric mucosa.
Increased telomerase activities in human pancreatic duct adenocarcinomas.
Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung.
Increased telomerase activity and hTERT expression in human salivary gland carcinomas.
Indomethacin and telomerase activity in tumor growth retardation.
Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres.
Induction of apoptosis and inhibition of telomerase activity by aqueous extract from Platycodon grandiflorum in human lung carcinoma cells.
Induction of apoptosis and inhibition of telomerase activity in human lung carcinoma cells by the water extract of Cordyceps militaris.
Induction of apoptosis by hexamethylene bisacetamide is p53-dependent associated with telomerase activity but not with terminal differentiation.
Induction of telomerase activity and chromosome aberrations in human tumour cell lines following X-irradiation.
Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells.
Inhibition of human telomerase by a retrovirus expressing telomeric antisense RNA.
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
Inhibition of telomerase activity as a measure of tumor cell killing by cisplatin in squamous cell carcinoma cell line.
Inhibition of telomerase activity in human cancer cells by RNA interference.
Inhibition of telomerase activity in renal cell carcinoma cells by doxorubicin and anti-Fas monoclonal antibody.
Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells.
Inhibitory effects of Gleditsia sinensis fruit extract on telomerase activity and oncogenic expression in human esophageal squamous cell carcinoma.
Intact functional domains of the retinoblastoma gene product (pRb) are required for downregulation of telomerase activity.
Intensive Inhibition of hTERT Expression by a Ribozyme Induces Rapid Apoptosis of Cancer Cells through a Telomere Length-Independent Pathway.
Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32.
KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth.
Label-free, PCR-free chip-based detection of telomerase activity in bladder cancer cells.
Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.
Localization of telomerase hTERT protein and hTR in benign mucosa, dysplasia, and squamous cell carcinoma of the cervix.
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Loss of heterozygosity at chromosome 3p correlates with telomerase activity in renal cell carcinoma.
Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.
Low frequency of positive telomerase activity in a chromophobe subtype of renal cell carcinoma.
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
Mechanism of telomerase repression during terminal differentiation of normal epithelial cells and squamous carcinoma lines.
Merkel cell polyomavirus in non-small cell lung carcinomas from Chile.
MG-132 inhibits telomerase activity, induces apoptosis and G(1) arrest associated with upregulated p27kip1 expression and downregulated survivin expression in gastric carcinoma cells.
Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines.
miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.
Missing association between telomerase activity and clinicopathological features in patients with early stage carcinoma of the cervix.
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression.
Modulation of telomerase activity by zinc in human prostatic and renal cancer cells.
Molecular alterations in endometrial and ovarian clear cell carcinomas: clinical impacts of telomerase reverse transcriptase promoter mutation.
Molecular characterization of head and neck tumors by analysis of telomerase activity and a panel of microsatellite markers.
Molecular cytogenetic analyses of hTERC (3q26) and MYC (8q24) genes amplifications in correlation with oncogenic human papillomavirus infection in Czech patients with cervical intraepithelial neoplasia and cervical carcinomas.
Molecular detection and characterization of circulating tumor cells and micrometastases in prostatic, urothelial, and renal cell carcinomas.
Molecular diagnosis of pancreatic cancer.
Molecular staging of surgical margins after radical prostatectomy by detection of telomerase activity.
Mouse models for the study of telomerase.
Mutations in TERT promoter and FGFR3 and telomere length in bladder cancer.
Negative Prognostic Implication of TERT Promoter Mutations in Human Papillomavirus-Negative Tonsillar Squamous Cell Carcinoma Under the New 8th AJCC Staging System.
New quinolones, ofloxacin and levofloxacin, inhibit telomerase activity in transitional cell carcinoma cell lines.
Non-invasive methods of bladder cancer detection.
Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine.
Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.
Nuclear hTERT immunohistochemical expression is associated with survival of patients with urothelial bladder cancer.
Oesophageal basaloid squamous cell carcinoma: a unique clinicopathological entity with telomerase activity as a prognostic indicator.
Oncofoetal fibronectin--a tumour-specific marker in detecting minimal residual disease in differentiated thyroid carcinoma.
Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas.
P53 expression, p53 and Ha-ras mutation and telomerase activation during nitrosamine-mediated hamster pouch carcinogenesis.
p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma.
Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Patterns of gene expression in pituitary carcinomas and adenomas analyzed by high-density oligonucleotide arrays, reverse transcriptase-quantitative PCR, and protein expression.
PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway.
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Polygala tenuifolia polysaccharide (PTP) inhibits cell proliferation by repressing Bmi-1 expression and downregulating telomerase activity.
Positive expression of Lin28 is correlated with poor survival in gastric carcinoma.
Possible role of telomerase activation in the cancer predisposition of patients with hereditary nonpolyposis colorectal cancers.
Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis.
Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells.
Precancerous hepatic nodules had significant levels of telomerase activity determined by sensitive quantitation using a hybridization protection assay.
Predicting clinical outcome in feline oral squamous cell carcinoma: tumour initiating cells, telomeres and telomerase.
Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation.
Predictive and prognostic significance of telomerase levels/telomere length in tissues and peripheral blood in head and neck squamous cell carcinoma.
Preoperative diagnosis of intraductal papillary-mucinous tumors of the pancreas with attention to telomerase activity.
Prevalence of telomerase activity in human cancer.
Production of spindle cell carcinoma by transduction of H-Ras 61L into immortalized human mammary epithelial cells.
Prognostic relevance of human telomerase reverse transcriptase (hTERT) expression in patients with gall bladder disease and carcinoma.
Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis.
Prognostic Significance of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression in Ampullary Carcinoma.
Prognostic value of cell-cycle regulators and cellular biomarkers in laryngeal squamous cell carcinoma.
Prognostic value of human telomerase reverse transcriptase gene expression in oral carcinogenesis.
Prognostic value of telomerase and DNA ploidy in laryngeal carcinoma.
Promoter region mutations of the telomerase reverse transcriptase (TERT) gene in head and neck squamous cell carcinoma.
Prostate-specific antigen (protein and mRNA) analysis in the differential diagnosis and staging of prostate cancer.
Quantification of alternative splicing variants of human telomerase reverse transcriptase and correlations with telomerase activity in lung cancer.
Quantification of hTERT mRNA and telomerase activity in bladder washings of patients with recurrent urothelial cell carcinomas.
Quantification of telomerase activity in normal oral mucosal tissue and oral squamous cell carcinoma.
Quantification of telomerase activity of regions unstained with iodine solution that surround oral squamous cell carcinoma.
Quantitative analysis of hTERT mRNA expression in colorectal cancer.
Quantitative analysis of telomerase activity and telomerase reverse transcriptase expression in renal cell carcinoma.
Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma.
Quantitative analysis of telomerase in feline mammary tissues.
Quantitative assay of telomerase activity in head and neck squamous cell carcinoma and other tissues.
Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer.
Quantitative determination of telomerase activity in breast cancer and benign breast diseases.
Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas.
Quantitative measurement of telomerase reverse transcriptase (hTERT) mRNA in urothelial cell carcinomas.
Radiation-induced effects on telomerase in gynecological cancer cell lines with different radiosensitivity and repair capacity.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Rapid, quantitative nonisotopic assay for telomerase activity in human tumors.
Rb and E2F-1 regulate telomerase activity in human cancer cells.
Real-time determination of human telomerase reverse transcriptase mRNA in gastric cancer.
Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas.
Regulation of Epithelial Cell Proliferation, Differentiation, and Plasticity by Grainyhead-Like 2 During Oral Carcinogenesis.
Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells.
Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix.
Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma.
Relationship between the expression of telomerase and human papillomavirus infection in invasive uterine cervical carcinoma.
Renal cell carcinoma (RCC) and telomerase activity: relationship to stage.
Repression of telomerase reverse transcriptase mRNA and hTERT promoter by gambogic acid in human gastric carcinoma cells.
Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence.
Resistance to telomerase inhibition by human squamous cell carcinoma cell lines.
Retinoic acid suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma.
RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.
Role of telomerase in anticancer activity of pristimerin in prostate cancer cells.
Role of vaccine therapy for renal cell carcinoma in the era of targeted therapy.
Sarcomatoid Renal Cell Carcinoma With Unusual Metastasis to the Small Intestine Manifesting as Perforated Appendicitis.
Selective suppression of autocatalytic caspase-3 driven by two-step transcriptional amplified human telomerase reverse transcriptase promoter on ovarian carcinoma growth in vitro and in mice.
Semi-quantitative analysis of telomerase activity in exfoliated human urothelial cells and bladder transitional cell carcinoma.
Semi-quantitative analysis of telomerase activity in human urothelial cells and bladder transitional cell carcinoma.
Semi-quantitative procedure for telomeric repeat amplification protocol (TRAP) assay in colorectal carcinomas.
Sensitive detection of circulating breast cancer cells by reverse-transcriptase polymerase chain reaction of maspin gene.
Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction.
Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.
Short hairpin ribonucleic acid targeting the telomerase catalytic unit of messenger ribonucleic acid significantly limits the growth of laryngeal squamous cell carcinoma in nude mice.
Shortened telomere length and increased telomerase activity in hamster pancreatic duct adenocarcinomas and cell lines.
Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension.
Significant telomere reduction in human superficial transitional cell carcinoma.
Simultaneous over activation of EGFR, telomerase (h TERT), and cyclin D1 correlates with advanced disease in larynx squamous cell carcinoma: a tissue microarray analysis.
Soluble purified recombinant C2ORF40 protein inhibits tumor cell growth in vivo by decreasing telomerase activity in esophageal squamous cell carcinoma.
Stem cell features of benign and malignant prostate epithelial cells.
Suppression of cell proliferation and telomerase activity in 4-(hydroxyphenyl)retinamide-treated mammary tumors.
Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element.
Survivin and telomerase expression in the uterine cervix of women with human papillomavirus-induced lesions.
Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113).
Targeted sequencing of Plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations.
Targeted therapy of human laryngeal squamous cell carcinoma in vitro by antisense oligonucleotides directed against telomerase reverse transcriptase mRNA.
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Telomerase (TERT) promoter mutations are infrequent in Merkel cell carcinomas.
Telomerase activation and cell proliferation during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Telomerase activation cooperates with inactivation of p16 in early head and neck tumorigenesis.
Telomerase activation in adenocarcinoma-bronchioloalveolar carcinoma.
Telomerase activation in cervical neoplasia.
Telomerase activation in colorectal carcinogenesis.
Telomerase activation in in vitro and in vivo cervical carcinogenesis.
Telomerase activation in neoplastic cell immortalization and tumour progression.
Telomerase activation--one step on the road to carcinoma of the gall bladder.
Telomerase activity analysis of esophageal carcinoma using microdissection-TRAP assay.
Telomerase activity and cytokeratin 20 as markers for the detection and followup of transitional cell carcinoma: an unfulfilled promise.
Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues.
Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas.
Telomerase activity and expression of its RNA component in cervical lesions.
Telomerase activity and expression of telomerase genes in squamous dysplasia and squamous cell carcinoma of the esophagus.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity and human papillomavirus in malignant, premalignant and benign cervical lesions.
Telomerase activity and in situ telomerase RNA expression in oral carcinogenesis.
Telomerase activity and its inhibition in benign and malignant breast lesions.
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
Telomerase activity and p53 expression in pterygia.
Telomerase activity and p53 gene mutation in familial polyposis coli.
Telomerase activity and survival of late-stage South African esophageal carcinoma patients.
Telomerase activity and telomere length in different areas of renal cell carcinoma.
Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents.
Telomerase activity and telomere lengths: alterations in renal cell carcinomas.
Telomerase activity as a biological marker in some gynecological tumors: comparison with tissue and serum CA 125.
Telomerase activity as a marker of invasive ductal breast carcinomas on FNABs and relationship to other prognostic variables.
Telomerase activity as a potential marker in preneoplastic bladder lesions.
Telomerase activity as a prognostic factor in colorectal cancer.
Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer.
Telomerase activity as an indicator of malignant potential in iodine-nonreactive lesions of the esophagus.
Telomerase activity as an indicator of potentially malignant adrenal tumors.
Telomerase activity associated with acquisition of malignancy in human colorectal cancer.
Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer.
Telomerase activity could be used as a marker for neoplastic transformation in gastric adenocarcinoma: but it does not have a prognostic significance.
Telomerase activity detected by quantitative assay in bladder carcinoma and exfoliated cells in urine.
Telomerase activity during carcinogenesis in the bronchus.
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA.
Telomerase activity in benign and malignant cytologic fluids.
Telomerase activity in benign and malignant epithelial ovarian tumors.
Telomerase activity in benign and malignant human thyroid tissues.
Telomerase activity in benign and malignant thyroid diseases.
Telomerase activity in benign and malignant thyroid tumors.
Telomerase activity in bladder cancer tissue.
Telomerase activity in bladder cancer, bladder washings and in urine.
Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine.
Telomerase activity in cervical intraepithelial neoplasia.
Telomerase activity in cervical smears.
Telomerase activity in colorectal cancer and its relationship to bcl-2 expression.
Telomerase activity in esophageal carcinoma.
Telomerase activity in esophageal squamous cell carcinoma and lesions unstained with Lugol's solution.
Telomerase activity in esophageal squamous cell carcinoma: down-regulation by chemotherapeutic agent.
Telomerase activity in fine needle aspiration biopsy samples: application to diagnosis of human thyroid carcinoma.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in gastrointestinal stromal tumors.
Telomerase activity in gestational trophoblastic disease.
Telomerase activity in giant condyloma acuminatum.
Telomerase activity in gynecologic tumors.
Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.
Telomerase activity in head and neck tumors after introduction of wild-type p53, p21, p16, and E2F-1 genes by means of recombinant adenovirus.
Telomerase activity in HeLa cervical carcinoma cell line proliferation.
Telomerase activity in high-grade cervical lesions is associated with allelic imbalance at 6Q14-22.
Telomerase activity in human gynaecological malignancies.
Telomerase activity in human laryngeal squamous cell carcinomas.
Telomerase activity in human ovarian carcinoma.
Telomerase activity in human proliferative breast lesions.
Telomerase activity in human renal cell carcinoma.
Telomerase activity in human thyroid carcinomas originating from the follicular cells.
Telomerase activity in Indian patients with carcinomas of the aerodigestive tract.
Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.
Telomerase activity in laryngeal squamous cell carcinoma.
Telomerase activity in lesions of the thyroid: application to diagnosis of clinical samples including fine-needle aspirates.
Telomerase activity in malignant and benign renal tumors.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase activity in non-small cell lung carcinomas correlates with smoking status.
Telomerase activity in normal leukocytes and in hematologic malignancies.
Telomerase activity in oral and maxillofacial tumors.
Telomerase activity in oral cancer.
Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma.
Telomerase activity in oral squamous cell carcinoma.
Telomerase activity in pancreatic endocrine tumors.
Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
Telomerase activity in patients with transitional cell carcinoma: a preliminary study.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium.
Telomerase activity in proximal and distal gastric neoplastic and preneoplastic lesions using immunohistochemical detection of hTERT.
Telomerase activity in pulmonary neuroendocrine tumors: correlation with histologic subtype (MS-0060).
Telomerase activity in radiation-induced chronic human skin ulcers.
Telomerase activity in renal cell carcinoma by modified telomeric repeat amplification protocol assay.
Telomerase activity in renal cell carcinoma.
Telomerase activity in sex cord-stromal tumors of the ovary.
Telomerase activity in small cell esophageal carcinoma.
Telomerase activity in soft-tissue and bone sarcomas.
Telomerase activity in solid transitional cell carcinoma, bladder washings, and voided urine.
Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid.
Telomerase activity in the female reproductive tract and neoplasms.
Telomerase activity in the normal and neoplastic rat mammary gland.
Telomerase activity in the occurrence and progression of oral squamous cell carcinoma.
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.
Telomerase activity in the vaginal margins of radical hysterectomy in patients with carcinoma of the cervix: correlation with histology and human papillomavirus.
Telomerase activity in thyroid malignancy.
Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT).
Telomerase activity in touch-imprint cell preparations from fresh prostate needle biopsy specimens.
Telomerase activity in urine in diagnosis and recurrence surveillance of urothelial carcinoma.
Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer.
Telomerase activity in vivo in human malignant hematopoietic cells.
Telomerase activity is correlated with lower grade and lower stage bladder carcinomas.
Telomerase activity is frequently found in metaplastic and malignant human nasopharyngeal tissues.
Telomerase activity is not a key determinant of sensitivity to standard cytotoxic drugs in human esophageal carcinoma cell lines.
Telomerase activity is significantly enhanced in malignant adrenocortical tumors in comparison to benign adrenocortical adenomas.
Telomerase activity is upregulated in laryngeal squamous cell carcinoma.
Telomerase activity levels in the surgical margin and tumour distant tissue of the squamous cell carcinoma of the head-and-neck.
Telomerase activity of basal cell carcinoma in patients living in North Queensland, Australia.
Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion.
Telomerase activity of Merkel cell carcinomas and Merkel cell carcinoma-derived cell cultures.
Telomerase activity of peripheral blood mononuclear cells from patients with laryngeal carcinoma.
Telomerase activity of the Lugol-stained and -unstained squamous epithelia in the process of oesophageal carcinogenesis.
Telomerase activity, expression of Bcl-2 and cell cycle regulation in doxorubicin resistant gastric carcinoma cell lines.
Telomerase activity, telomere length, and apoptosis: a comparison between acquired cholesteatoma and squamous cell carcinoma.
Telomerase activity, telomere length, and DNA ploidy in prostatic intraepithelial neoplasia (PIN).
Telomerase activity: a biomarker of cell proliferation, not malignant transformation.
Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.
Telomerase activity: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase and human papillomavirus as diagnostic adjuncts for cervical dysplasia and carcinoma.
Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma.
Telomerase as a potential marker for early diagnosing cervical carcinoma.
Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hTERT and hTR.
Telomerase as an independent prognostic factor in head and neck squamous cell carcinoma.
Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study.
Telomerase catalytic subunit in laryngeal carcinogenesis--an immunohistochemical study.
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene.
Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.
Telomerase elevation in pancreatic ductal carcinoma compared to nonmalignant pathological states.
Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma.
Telomerase expression in lung preneoplasia and neoplasia.
Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma.
Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix.
Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Telomerase expression in sebaceous carcinoma of the eyelid.
Telomerase expression in sebaceous lesions of the skin.
Telomerase gene expression in intraductal papillary-mucinous tumors (IPMT): preliminary findings.
Telomerase hTR and hTRT gene expression in oral precancerous lesions and squamous cell carcinomas.
Telomerase in saliva: An assistant marker for oral squamous cell carcinoma.
Telomerase in urological malignancy.
Telomerase inhibition and the future management of head-and-neck cancer.
Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.
Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma.
Telomerase pulsed dendritic cells for immunotherapy for renal cell carcinoma.
Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases.
Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With Felis catus Papillomavirus Type-2 Infection.
Telomerase reverse transcriptase (TERT) promoter mutation analysis of benign, malignant and reactive urothelial lesions reveals a subpopulation of inverted papilloma with immortalizing genetic change.
Telomerase reverse transcriptase (TERT) promoter mutations are rare in urachal cancer.
Telomerase reverse transcriptase (TERT) promoter mutations in primary adenocarcinoma of bladder and urothelial carcinoma with glandular differentiation: pathogenesis and diagnostic implications.
Telomerase reverse transcriptase interference synergistically promotes tumor necrosis factor?related apoptosis?inducing ligand?induced oral squamous cell carcinoma apoptosis and suppresses proliferation in vitro and in vivo.
Telomerase reverse transcriptase mediates EMT through NF-?B signaling in tongue squamous cell carcinoma.
Telomerase reverse transcriptase potentially promotes the progression of oral squamous cell carcinoma through induction of epithelial-mesenchymal transition.
Telomerase reverse transcriptase promoter mutations in glandular lesions of the urinary bladder.
Telomerase reverse transcriptase promotes the proliferation of human laryngeal carcinoma cells through activation of the activator protein 1.
Telomerase reverse transcriptase subunit immunoreactivity: a marker for high-grade prostate carcinoma.
Telomerase RNA expression and DNA ploidy as prognostic markers of prostate carcinomas.
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.
Telomerase, cervical cancer, and human papillomavirus.
Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase: An exploration toward the end of cancer.
Telomerase: its clinical relevance in the diagnosis of bladder cancer.
Telomere Dysfuction Promotes Metastasis in a TERC Null Mouse Model of Head and Neck Cancer.
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.
Telomere length and telomerase subunits as diagnostic and prognostic biomarkers in Barrett carcinoma.
Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas.
Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesions.
Telomere shortening in gastric carcinoma with aging despite telomerase activation.
Telomere shortening in mucosa surrounding the tumor: biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell carcinoma.
Telomere shortening in renal cell carcinoma.
Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma.
Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.
Telomeres and telomerase in sarcomas.
Telomeres and Telomerase in the Development of Liver Cancer.
Telomeres and thyroid cancer.
TERT C228T mutation in non-malignant bladder urothelium is associated with intravesical recurrence for patients with non-muscle invasive bladder cancer.
TERT promoter hotspot mutations and their relationship with TERT levels and telomere erosion in patients with head and neck squamous cell carcinoma.
TERT promoter mutation in patients with second primary of tongue squamous cell carcinoma.
TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.
TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma.
TERT promoter mutations in clear cell renal cell carcinoma.
TERT promoter mutations in periocular carcinomas: implications of ultraviolet light in pathogenesis.
TERT promoter mutations in telomere biology.
TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine.
TERT Promoter Mutations Reactivate Telomerase in Urothelial Carcinoma.
The alternative lengthening of telomeres pathway may operate in non-neoplastic human cells.
The association between telomerase, histopathological parameters, and KI-67 expression in breast cancer.
The breakdown of apoptotic mechanism in the development and progression of colorectal carcinoma.
The clinical implications of telomerase activity in upper tract urothelial cancer and washings.
The consequences of insulin-like growth factors/receptors dysfunction in lung cancer.
The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration.
The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with nonsmall cell lung carcinoma.
The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.
The effect of vitamin E acetate on ultraviolet-induced mouse skin carcinogenesis.
The expression of hTERT mRNA and cellular immunity in gastric cancer and precancerosis.
The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation.
The influence of reactivation of the telomerase in tumour tissue on the prognosis of squamous cell carcinomas in the head and neck.
The inhibitory effect of Gleditsia sinensis on cyclooxygenase-2 expression in human esophageal squamous cell carcinoma.
The molecular detection of circulating tumor cells in bladder cancer using telomerase activity.
The multi-step process of human skin carcinogenesis: a role for p53, cyclin D1, hTERT, p16, and TSP-1.
The opposing effect of hypoxia-inducible factor-2alpha on expression of telomerase reverse transcriptase.
The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells.
The retrovirus-mediated antisense human telomerase RNA (hTR) gene limits the growth of hepatocellular carcinoma growth in cell culture and animals.
The role of HPV oncoproteins and cellular factors in maintenance of hTERT expression in cervical carcinoma cells.
The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma.
The significant diagnostic value of human telomerase RNA component (hTERC) gene detection in high-grade cervical lesions and invasive cancer.
The Small Molecule BIBR1532 Exerts Potential Anti-cancer Activities in Preclinical Models of Feline Oral Squamous Cell Carcinoma Through Inhibition of Telomerase Activity and Down-Regulation of TERT.
The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cells.
Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase 1/2 trial.
Therapeutic efficacy of an hTERT promoter-driven oncolytic adenovirus that expresses apoptin in gastric carcinoma.
Transcription and alternative splicing of telomerase reverse transcriptase in benign and malignant breast tumours and in adjacent mammary glandular tissues: implications for telomerase activity.
Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2'-O-Methyl-RNA.
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization.
Uncommon Human Telomerase Reverse Transcriptase Promoter Mutations Are Associated With Poor Survival in Ovarian Clear Cell Carcinoma.
Up-regulation of human telomerase catalytic subunit during gastric carcinogenesis.
Upregulated p27kip1 can Downregulate Survivin Expression and Inhibit Telomerase Activity in Gastric Carcinoma Cells.
Value of endoscopic methylene blue and Lugol's iodine double staining and detection of GST-Pi and telomerase in the early diagnosis of esophageal carcinoma.
Variable expression of the transcription factors cAMP response element-binding protein and inducible cAMP early repressor in the normal adrenal cortex and in adrenocortical adenomas and carcinomas.
Wilms' tumour 1 can suppress hTERT gene expression and telomerase activity in clear cell renal cell carcinoma via multiple pathways.
YY1 Promotes Telomerase Activity and Laryngeal Squamous Cell Carcinoma Progression Through Impairment of GAS5-Mediated p53 Stability.
[Actinic keratoses]
[Analysis of telomerase activity in esophageal carcinoma using microdissection telomeric repeat amplification protocol assay]
[Analysis of telomeric length in epithelial carcinoma of the ovary]
[Change of Bcl-2 expression and telomerase during apoptosis induced by oridonin on human hepatocelluar carcinoma cells]
[Clinical significance of detecting telomerase activity in ascites cells from patients with ovarian carcinoma]
[Construction of autocatalytic caspase-3 driven by amplified human telomerase reverse transcriptase promoter and its enhanced efficacy of inducing apoptosis in human ovarian carcinoma]
[Correlations of telomere length and telomerase activity to radiosensitivity of human laryngeal squamous carcinoma cells]
[Detection and effect of telomerase activity in oral mucosal squamous cell carcinoma]
[Detection of telomerase activity by semi-quantitative and in situ assays and quantification of hTERT expression in bladder carcinomas]
[Detection of telomerase activity in laryngeal carcinoma and the association between telomerase activity and lymphatic metastasis]
[Detection of telomerase activity of exfoliated cells in bile and its clinical impact]
[Detection of telomerase hTERT gene expression of exfoliated cell in broncho-alveolar lavage fluid]
[Effect of inhibition of polyamine biosynthesis on the growth and telomerase activity of human laryngeal carcinoma cells Hep-2]
[Effect of Matrine on cell cycle and human telomerase reverse transcriptase of human salivary adenoid cystic carcinoma]
[Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]
[Evaluation of telomerase activation in laryngeal mucosa adjacent to carcinoma]
[Expression and significance of telomerase reverse transcriptase and its regulators in non-small cell lung carcinoma]
[Expression of human telomerase reverse transcriptase in renal cell carcinoma and its clinical significance]
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
[Expression of telomerase genes hTRTmRNA in oral squamous cell carcinomas.]
[Expression of telomerase reverse transcriptase and its relationship with expression of c-myc in laryngeal squamous cell carcinomas]
[Expression of telomerase reverse transcriptase in premalignant esophageal squamous dysplasia]
[Expression of telomere and telomerase in human primary gastric carcinoma]
[General rules for the study of pancreatic cancer by molecular biological aspect]
[Genetic alterations in stomach cancer]
[Genic alterations in oral and head and neck squamous cell carcinomas: analysis of international literature]
[Hormone-dependent expression of oncovirus genomes in stable mouse mammary cancer cell line GR and RIII]
[hTERT promoter enhances the radiosensitivity to gene-radiation therapy of human laryngeal carcinoma transplanted in nude mice]
[Inhibitory effect of antisense human telomerase reverse transcriptase(hTERT) on telomerase activity of human pulmonary giant cell carcinoma cell line(PLA-801D)]
[Inhibitory effect of hTERT dsRNA on telomerase activity in lung carcinoma cell line A549]
[Inhibitory effect of p53 gene on telomerase activity and proliferative activity in salivary adenoid cystic carcinoma cells]
[Inhibitory Effect of Silencing hTERT Gene by Short Hairpin RNA on Growth of Human Laryngeal Squamous Cell Carcinoma Xenograft in Nude Mice.]
[Modified quantitative determination of telomerase activity in human head and neck malignant tumor]
[Prognostic factors of infiltrating bladder tumors]
[Prognostic significance of hTERT mRNA quantitative expression in resected gastric carcinomas].
[Quantitative analysis of telomerase activity in exfoliated urothelial cells for the diagnosis of bladder carcinoma]
[Quantitative assay of telomerase activity in head and neck squamous cell carcinoma]
[Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck]
[Relationship among HPV16 infection and Expression of hTERT, p21waf1, Ki67 in cervical intraepithelial neoplasias and squamous cell carcinomas of cervix uteri]
[Relationship between human papillomavirus 16 infection and the expression of p33(ING1b), human telomerase reverse transcriptase in cervical squamous cell carcinoma of Uygur female in Xinjiang Uygur Autonomous Region]
[Research on expression of human papillomavirus type 16 and telomerase in oral lesions]
[Research on expression of telomerase hTR gene in oral precancerous lesion and squamous cell carcinoma]
[Specific activation of telomerase in pancreatic cancer tissue and preoperative diagnosis of pancreatic cancer by telomerase in pancreatic juice]
[Study and detection of telomerase activity in oral squamous cell carcinomas and precancerous lesions]
[Study of telomerase activity in colorectal carcinomas]
[Study on the clinical value of telomerase activity in exfoliated cells of sputum from lung cancer patients.]
[Targeted therapy of human laryngeal squamous cell carcinoma in vitro with telomerase catalytic subunit mRNA]
[Telomerase activity in cervical carcinoma and cervical intraepithelial neoplasia and its correlation to classification of koilocytosis]
[Telomerase activity in colorectal carcinoma and its relationship to clinicopathological findings]
[Telomerase activity in esophageal carcinoma and lesions unstained with Lugol's solution]
[Telomerase activity in esophageal squamous cell carcinoma and in normal esophageal epithelium adjacent to carcinoma]
[Telomerase activity in human gastric and colorectal cancer]
[Telomerase activity in human head and neck squamous cell carcinoma and adjacent tissues]
[Telomerase activity in human primary lung caner.]
[Telomerase activity in oral squamous cell carcinoma and leukoplakia]
[Telomerase activity in pancreatic juice for the preoperative diagnosis of pancreatic cancer]
[Telomerase activity of tumors in the head and neck]
[Telomerase and gastrointestinal cancer]
[Telomerase expression in tarsal gland carcinoma]
[Telomerase in lung cancer. Testing the activity of the "immortaligy enzyme" bronchial biopsies increases the diagnostic yield in cases of suspected peripheral bronchogenic carcinomas]
[Telomerase level versus spliced hTERT-specific RNA forms in cervical carcinoma]
[Telomerase SiRNA inhibits KB cell growth in human oral squamous cell carcinoma.]
[The detection and clinical significance of telomerase activity in supraglottic carcinomas]
[The effect of hepatitis B virus X gene transfection on expression of human telomerase reverse transcriptase mRNA in human bile duct carcinoma cell lines]
[The effects on expressions of p53 and PCNA by inhibition of hTERT with siRNA in transplantable model of human laryngeal squamous carcinoma in nude mice]
[The efficacy of autocatalytic casapse-3 driven by human telomerase reverse transcriptase promoter on human ovarian carcinoma]
[The expression and significance of human telomerase reverse transcriptase protein and gene in bile duct carcinomas and their adjacent tissues]
[The expressions of telomerase activity and cyclinD1 protein in laryngeal squamous cell carcinoma]
[The role of telomerase for pancreatic carcinogenesis in human and hamster]
[To inhibit ERK for enhancing chemotherapy sensitivity of drug-resistance cell lines of leukemia and ovarian carcinoma]
Carcinoma in Situ
Comparison of screening methods in the detection of bladder cancer.
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions.
Telomerase activation and cell proliferation during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.
Telomerase activity and p53 expression in pterygia.
Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer.
Telomerase activity as an indicator of malignant potential in iodine-nonreactive lesions of the esophagus.
Telomerase activity in oral cancer.
Telomerase activity: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase catalytic subunit in laryngeal carcinogenesis--an immunohistochemical study.
Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma.
Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix.
Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas.
Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesions.
[Telomerase activity in pancreatic juice for the preoperative diagnosis of pancreatic cancer]
Carcinoma, Acinar Cell
Telomerase activity in oral cancer.
Telomerase activity in pancreatic endocrine tumors.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Carcinoma, Adenoid Cystic
Telomerase activity in oral cancer.
[Effect of Matrine on cell cycle and human telomerase reverse transcriptase of human salivary adenoid cystic carcinoma]
[Inhibitory effect of p53 gene on telomerase activity and proliferative activity in salivary adenoid cystic carcinoma cells]
Carcinoma, Adenosquamous
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Carcinoma, Basal Cell
Clinical significance of telomerase activity in basal cell carcinomas and in tumour-free surgical margins.
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Evaluation of telomerase in non-melanoma skin cancer.
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase activity of basal cell carcinoma in patients living in North Queensland, Australia.
Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma.
TERT promoter mutations in periocular carcinomas: implications of ultraviolet light in pathogenesis.
Carcinoma, Bronchogenic
[Telomerase in lung cancer. Testing the activity of the "immortaligy enzyme" bronchial biopsies increases the diagnostic yield in cases of suspected peripheral bronchogenic carcinomas]
Carcinoma, Ductal
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
Comparison of Telomere Length and Telomerase Activation between Breast Fibroadenoma and Infiltrating Ductal Carcinoma in Malaysian Women.
Culture models of human mammary epithelial cell transformation.
Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ.
Investigation of telomerase activity and apoptosis on invasive ductal carcinoma of the breast using immunohistochemical and Western blot methods.
Telomerase activity in ductal carcinoma in situ and invasive breast cancer.
Telomerase activity in ductal carcinoma in situ of the breast.
Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome.
Telomerase activity in normal and neoplastic breast.
Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
[Telomerase activity in infiltration ductal carcinoma of breast]
Carcinoma, Ductal, Breast
[The diagnostic value of RNA oncomarkers in evaluation of malignant breast tumors].
Carcinoma, Embryonal
Immortalization of neural precursors when telomerase is overexpressed in embryonal carcinomas and stem cells.
Low level expression of human telomerase reverse transcriptase predicts cancer-related death and progression in embryonal carcinoma.
Reverse transcriptase activity from human embryonal carcinoma cells NTera2D1.
Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines.
Telomerase activity in germ cell cancers and mature teratomas.
Telomerase activity is repressed during differentiation of maturation-sensitive but not resistant human tumor cell lines.
Carcinoma, Endometrioid
High telomerase activity is associated with cell cycle deregulation and rapid progression in endometrioid adenocarcinoma of the uterus.
Quantitative analysis of telomerase hTERT mRNA and telomerase activity in endometrioid adenocarcinoma and in normal endometrium.
Telomerase activity in gynecological tumors.
Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma.
Carcinoma, Giant Cell
[Inhibitory effect of antisense human telomerase reverse transcriptase(hTERT) on telomerase activity of human pulmonary giant cell carcinoma cell line(PLA-801D)]
Carcinoma, Hepatocellular
A Bioinformatics Analysis Identifies the Telomerase Inhibitor MST-312 for Treating High-STMN1-Expressing Hepatocellular Carcinoma.
A hemagglutinin from the medicinal fungus Cordyceps militaris.
A multi-target protein of hTERTR-FAM96A presents significant anticancer potent in the treatment of hepatocellular carcinoma.
A novel and exploitable antifungal peptide from kale (Brassica alboglabra) seeds.
A novel biomarker TERTmRNA is applicable for early detection of hepatoma.
A novel platinum compound inhibits telomerase activity in vitro and reduces telomere length in a human hepatoma cell line.
A phase II open label trial evaluating safety and efficacy of a telomerase peptide vaccination in patients with advanced hepatocellular carcinoma.
A trypsin-chymotrypsin inhibitor with antiproliferative activity from small glossy black soybeans.
Abnormal expression of hepatomas and circulating telomerase and its clinical values.
Adeno-associated virus type 2 as an oncogenic virus in human hepatocellular carcinoma.
Advantages of assaying telomerase activity in ascites for diagnosis of digestive tract malignancies.
Alpha-fetoprotein and human telomerase reverse transcriptase mRNA levels in peripheral blood of patients with hepatocellular carcinoma.
Alteration of telomeric repeat length in hepatocellular carcinoma is independent of telomerase activity.
Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry-Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells.
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis.
Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells.
Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells.
Antitumor activity of an hTERT promoter-regulated tumor-selective oncolytic adenovirus in human hepatocellular carcinoma.
Antitumor and HIV-1 Reverse Transcriptase Inhibitory Activities of a Hemagglutinin and a Protease Inhibitor from Mini-Black Soybean.
Antitumoural immunity by virus-mediated immunogenic apoptosis inhibits metastatic growth of hepatocellular carcinoma.
Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.
Azidothymidine treatment of hepatocellular carcinoma in rats: an in vivo study of telomerase inhibition.
Biopsy diagnosis of malignant versus benign liver "nodules": new helpful markers. An update.
Brassiparin, an antifungal peptide from Brassica parachinensis seeds.
Cellular distribution of telomerase reverse transcriptase in human hepatocellular carcinoma.
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells.
Clinical and pathological significance of myeloid differentiation factor 88 expression in human hepatocellular carcinoma tissues.
Clinical impact of serum transforming growth factor-alpha mRNA as a predictive biomarker for the prognosis of fulminant hepatitis.
Clinical implications of telomerase activity in resected hepatocellular carcinoma.
Clinical significance of telomerase activity in hepatocellular carcinoma.
Clinical Significance of Telomerase Reverse-Transcriptase Promoter Mutations in Hepatocellular Carcinoma.
Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer.
Combinational RNAi gene therapy of hepatocellular carcinoma by targeting human EGFR and TERT.
Combined Detection of mRNA Expression of Alpha-Fetoprotein in Peripheral Blood and Telomerase Activity of Monocytes in Hepatocellular Carcinoma Patients.
Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations.
Comparison between Platinum-Azidothymidine and Azidothymidine Effects on Bcl-2 and Telomerase Gene Expression in Rats with Hepatocellular Carcinoma.
Correlation between the expression of hTERT gene and the clinicopathological characteristics of hepatocellular carcinoma.
Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cells.
CpG island methylator phenotype association with upregulated telomerase activity in hepatocellular carcinoma.
Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinoma.
Dedifferentiation of human hepatocellular carcinoma up-regulates telomerase and Ki-67 expression.
Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells.
Detection of telomerase activity, telomerase RNA component, and telomerase reverse transcriptase in human hepatocellular carcinoma.
Detection of telomerase in hepatocellular carcinomas using a PCR ELISA assay: comparison with hTR expression.
Detection of TERT promoter mutation in serum cell-free DNA using wild-type blocking PCR combined with Sanger sequencing in hepatocellular carcinoma.
Development of a novel assay to quantify serum human telomerase reverse transcriptase messenger RNA and its significance as a tumor marker for hepatocellular carcinoma.
Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma.
Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma.
Effect of lidamycin on telomerase activity in human hepatoma BEL-7402 cells.
Effects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cells.
Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells.
Effects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells.
Effects of silymarin and silymarin-doxorubicin applications on telomerase activity of human hepatocellular carcinoma cell line HepG2.
Effects of treatment with platinum azidothymidine and azidothymidine on telomerase activity and bcl-2 concentration in hepatocellular carcinoma- induced rats.
Exploring the Interplay of Telomerase Reverse Transcriptase and ?-Catenin in Hepatocellular Carcinoma.
Expression of hTERT mRNA in a mortal liver cell line during S phase without detectable telomerase activity.
Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers.
Expression of telomerase activity and oxidative stress in human hepatocellular carcinoma with cirrhosis.
Expression of telomerase component genes in hepatocellular carcinomas.
Expression of telomerase in normal and malignant rat hepatic epithelia.
Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma.
Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.
Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
Genetic diagnostic test of hepatocellular carcinoma by telomerase catalytic subunit mRNA.
Growth inhibition of BEL-7404 human hepatoma cells by expression of mutant telomerase reverse transcriptase.
Hammerhead ribozyme-mediated inhibition of telomerase activity in extracts of human hepatocellular carcinoma cells.
HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes.
Hepatitis B virus core protein enhances human telomerase reverse transcriptase expression and hepatocellular carcinoma cell proliferation in a c-Ets2-dependent manner.
Hepatitis B virus protein preS2 potentially promotes HCC development via its transcriptional activation of hTERT.
Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase.
Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.
Hepatitis C virus core protein enhances Telomerase activity in Huh7 cells.
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
High telomerase activity and long telomeres in advanced hepatocellular carcinomas with poor prognosis.
HIV-Tat-mediated Delivery of an LPTS Functional Fragment Inhibits Telomerase Activity and Tumorigenecity of Hepatoma Cells.
Human hepatoma cell telomerase activity inhibition and cell cycle modulation by its RNA component antisense oligodeoxyribonucleotides.
Human Telomerase Reverse Transcriptase Gene Promoter Mutation in Serum of Patients with Hepatocellular Carcinoma.
Human telomerase reverse transcriptase messenger RNA (TERT mRNA) as a tumour marker for early detection of hepatocellular carcinoma.
Identification of serum anti-human telomerase reverse transcriptase (hTERT) auto-antibodies during progression to hepatocellular carcinoma.
Immune response to human telomerase reverse transcriptase-derived helper T cell epitopes in hepatocellular carcinoma patients.
Immuno-histochemical detection of human telomerase reverse transcriptase in human liver tissues.
Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma.
Impact of mitochondrial telomerase over-expression on drug resistance of hepatocellular carcinoma.
In situ detection of telomerase enzymatic activity in human hepatocellular carcinogenesis.
In vitro effects on proliferation, telomerase activity and apoptosis of an eremophilanoid sesquiterpene from Senecio oldhamianus maxim in cultured human tumor cell lines.
Inactivation of p16INK4 in hepatocellular carcinoma.
Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis.
Increased telomerase activity in hyperplastic nodules and hepatocellular carcinomas induced by a choline-deficient L-amino acid-defined diet in rats.
Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice.
Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells.
Inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell proliferation.
Inhibitory Effect of Nucleos(t)ide Analogs on Telomerase Activity and Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B.
Isolation and characterization of a lectin with potentially exploitable activities from caper (Capparis spinosa) seeds.
Isolation and Characterization of Juncin, an Antifungal Protein from Seeds of Japanese Takana ( Brassica juncea Var. integrifolia).
Isolation and identification of a novel polysaccharide-peptide complex with antioxidant, antiproliferative, and hypoglycemic activities from the abalone mushroom.
Isothiazolone derivatives selectively inhibit telomerase from human and rat cancer cells in vitro.
Knockdown of NHP2 inhibits hepatitis B virus X protein-induced hepatocarcinogenesis via repressing TERT expression and disrupting the stability of telomerase complex.
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Leucocyte telomere shortening is associated with nonalcoholic fatty liver disease-related advanced fibrosis.
Levels of telomerase catalytic subunit mRNA as a predictor of potential malignancy.
Lipid transfer proteins from Brassica campestris and mung bean surpass mung bean chitinase in exploitability.
Liver transplantation for hepatocellular carcinoma in a patient with a novel telomerase mutation and steatosis.
Liver-specific gene therapy of hepatocellular carcinoma by targeting human telomerase reverse transcriptase with pegylated immuno-lipopolyplexes.
Long-term exposure to zidovudine delays cell cycle progression, induces apoptosis, and decreases telomerase activity in human hepatocytes.
Marmorin, a new ribosome inactivating protein with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from the mushroom Hypsizigus marmoreus.
Methylation-related silencing of p14ARF gene correlates with telomerase activity and mRNA expression of human telomerase reverse transcriptase in hepatocellular carcinoma.
miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway.
Mistletoe lectin induces apoptosis and telomerase inhibition in human A253 cancer cells through dephosphorylation of Akt.
Modulation of human telomerase reverse transcriptase in hepatocellular carcinoma.
Musa acuminata (Del Monte banana) lectin is a fructose-binding lectin with cytokine-inducing activity.
Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carcinoma.
NAC selectively inhibit cancer telomerase activity: A higher redox homeostasis threshold exists in cancer cells.
Nanocurcumin-Mediated Down-Regulation of Telomerase Via Stimulating TGF?1 Signaling Pathway in Hepatocellular Carcinoma Cells
NF-kappaB p65 modulates the telomerase reverse transcriptase in the HepG? hepatoma cell line.
Nuclear telomerase is less accessible to antibody probing than known nuclear antigens: retrieval with new immunostaining buffer.
Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis.
Over-expression of LPTS-L in hepatocellular carcinoma cell line SMMC-7721 induces crisis.
Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase activation.
PAI-1, t-PA and circulating hTERT DNA as related to virus infection in liver carcinogenesis.
Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma.
Precancerous hepatic nodules had significant levels of telomerase activity determined by sensitive quantitation using a hybridization protection assay.
Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA.
Preoperative peripheral blood human telomerase reverse transcriptase mRNA concentration is not a prognostic factor for resection of hepatocellular carcinoma.
Programmed Death Receptor 1 (PD1) Knockout and Human Telomerase Reverse Transcriptase (hTERT) Transduction Can Enhance Persistence and Antitumor Efficacy of Cytokine-Induced Killer Cells Against Hepatocellular Carcinoma.
Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma.
Protective effect of HO-1 against oxidative stress in human hepatoma cell line (HepG2) is independent of telomerase enzyme activity.
PTEN and hTERT gene expression and the correlation with human hepatocellular carcinoma.
Purification and characterization of a laccase from the edible wild mushroom Tricholoma mongolicum.
Purification and Characterization of a Laccase with Inhibitory Activity toward HIV-1 Reverse Transcriptase and Tumor Cells from an Edible Mushroom (Pleurotus cornucopiae).
Purification and Characterization of an Antifungal Peptide with Potent Antifungal Activity but Devoid of Antiproliferative and HIV Reverse Transcriptase Activities from Legumi Secchi Beans.
Purification of a trypsin-stable lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activity.
Purification of melibiose-binding lectins from two cultivars of Chinese black soybeans.
Quantification of plasma hTERT DNA in hepatocellular carcinoma patients by quantitative fluorescent polymerase chain reaction.
Quantitation of telomerase activity in hepatocellular carcinoma: a possible aid for a prediction of recurrent diseases in the remnant liver.
Quantitative analysis and in situ localization of human telomerase RNA in chronic liver disease and hepatocellular carcinoma.
Quantitative evaluation of telomerase activity in small liver tumors: analysis of ultrasonography-guided liver biopsy specimens.
Radiosensitization to X-ray radiation by telomerase inhibitor MST-312 in human hepatoma HepG2 cells.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma.
Recombinant adenovirus infection suppresses hTERT expression through virus-associated RNA-mediated induction of type 1 interferon.
Reduced p21(WAF1/CIP1) expression and p53 mutation in hepatocellular carcinomas.
Reduced p27Kip1 expression in hepatocellular carcinomas.
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor.
Regulatory regions of growth-related genes can activate an exogenous gene of the alpha-fetoprotein promoter to a comparable degree in human hepatocellular carcinoma cells.
Relationship between microvessel density and telomerase activity in hepatocellular carcinoma.
Relationship Between Serum microRNA155 and Telomerase Expression in Hepatocellular Carcinoma.
Reversal of hepatoma cells resistance to anticancer drugs is correlated to cell proliferation kinetics, telomere length and telomerase activity.
RNAi-hTERT Inhibition Hepatocellular Carcinoma Cell Proliferation via Decreasing Telomerase Activity.
Role of mitochondrial translocation of telomerase in hepatocellular carcinoma cells with multidrug resistance.
Sensitive and specific detection of circulating cancer cells in patients with hepatocellular carcinoma; detection of human telomerase reverse transcriptase messenger RNA after immunomagnetic separation.
Sensitive detection of human telomerase reverse transcriptase mRNA in the serum of patients with hepatocellular carcinoma.
Serum human telomerase reverse transcriptase messenger RNA as a novel tumor marker for hepatocellular carcinoma.
Significance of telomerase activity in the diagnosis of small differentiated hepatocellular carcinoma.
Significance of TERT Genetic Alterations and Telomere Length in Hepatocellular Carcinoma.
Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy.
Sleeping Beauty-mediated suicide gene therapy of hepatocellular carcinoma.
Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells.
Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway.
Surgical significance of telomerase activity in noncancerous liver tissue from patients with hepatocellular carcinoma.
SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity.
Synergic effect of 3'-azido-3'-deoxythymidine and arsenic trioxide in suppressing hepatoma cells.
Synthetic RNA-dependent DNA polymerase activity in normal rat liver and hepatomas.
Telomerase activated thymidine analogue pro-drug is a new molecule targeting hepatocellular carcinoma.
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas.
Telomerase activation in human hepatocarcinogenesis.
Telomerase activation in liver regeneration and hepatocarcinogenesis: Dr. Jekyll or Mr. Hyde?
Telomerase activity and Nm23-H2 protein expression in hepatocellular carcinoma.
Telomerase activity and telomerase catalytic subunit in hepatocellular carcinoma.
Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease.
Telomerase activity and telomere length in human hepatocellular carcinoma.
Telomerase activity as a predictive marker for recurrence of hepatocellular carcinoma after hepatectomy.
Telomerase activity correlates with cell cycle regulators in human hepatocellular carcinoma.
Telomerase activity in hepatocellular carcinoma and adjacent liver tissues.
Telomerase activity in hepatocellular carcinoma as a predictor of postoperative recurrence.
Telomerase activity in human hepatocellular carcinoma: parallel correlation with human telomerase reverse transcriptase (hTERT) mRNA isoform expression but not with cell cycle modulators or c-Myc expression.
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.
Telomerase activity in peripheral blood for diagnosis of hepatoma.
Telomerase activity in precancerous hepatic nodules.
Telomerase activity in tumor and remnant liver as predictor of recurrence and survival in hepatocellular carcinoma after resection.
Telomerase activity of needle-biopsied liver samples: its usefulness for diagnosis and judgement of efficacy of treatment of small hepatocellular carcinoma.
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus status.
Telomerase and c-myc expression in hepatocellular carcinomas.
Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
Telomerase as a tool for the differential diagnosis of human hepatocellular carcinoma.
Telomerase assay for differentiating between malignancy-related and nonmalignant ascites.
Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.
Telomerase expression and p53 status in hepatocellular carcinoma.
Telomerase inhibition and telomere loss in BEL-7404 human hepatoma cells treated with doxorubicin.
Telomerase inhibition decreases alpha-fetoprotein expression and secretion by hepatocellular carcinoma cell lines: in vitro and in vivo study.
Telomerase is strongly activated in hepatocellular carcinoma but not in chronic hepatitis and cirrhosis.
Telomerase mRNA: a novel marker for hepatocellular carcinoma.
Telomerase reactivation is associated with hepatobiliary and pancreatic cancers.
Telomerase reverse transcriptase (TERT) promoter mutation correlated with intratumoral heterogeneity in hepatocellular carcinoma.
Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma.
Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease.
Telomerase reverse transcriptase mRNA expression and telomerase activity in hepatocellular carcinoma.
Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors.
Telomerase reverse transcriptase promoter methylation is related to a risk of recurrence in hepatocellular carcinoma.
Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis.
Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma.
Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma.
Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.
Telomere and telomerase in chronic liver disease and hepatocarcinoma.
Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.
Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target.
Telomere Length Variation in Tumor cells and Cancer-Associated Fibroblasts: Potential Biomarker for Hepatocellular Carcinoma.
Telomere shortening and telomerase reactivation in dysplastic nodules of human hepatocarcinogenesis.
Telomeres and telomerase: a dual role in hepatocarcinogenesis.
Telomeres and telomerase: new targets for the treatment of liver cirrhosis and hepatocellular carcinoma.
Telomeres, NAFLD and Chronic Liver Disease.
Telomeres, p53, HNF4?, and Liver Disease.
TERT promoter mutated circulating tumor DNA as a biomarker for prognosis in hepatocellular carcinoma.
TERT promoter mutations in telomere biology.
The Anticancer Efficacy of Platinum Azidothymidin on Hepatocellular Carcinoma Via Affecting the Telomerase and the BcL-2 Genes Expression.
The efficacy of combination therapy using adeno-associated virus-TRAIL targeting to telomerase activity and cisplatin in a mice model of hepatocellular carcinoma.
The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
The retrovirus-mediated antisense human telomerase RNA (hTR) gene limits the growth of hepatocellular carcinoma growth in cell culture and animals.
The role of previous infection of hepatitis B virus in Hbs antigen negative and anti-HCV negative Japanese patients with hepatocellular carcinoma: etiological and molecular biological study.
The role of telomerase activity in hepatocellular carcinoma.
The role of telomeres and telomerase in cirrhosis and liver cancer.
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma.
Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma.
Up-regulation of hTERT expression by low-dose cisplatin contributes to chemotherapy resistance in human hepatocellular cancer cells.
Using a non-radioisotopic, quantitative TRAP-based method detecting telomerase activities in human hepatoma cells.
[A DNA vector-based RNAi technology to inhibit the activity of the telomerase of cell line HCCLM3]
[Effect of cell cycle on telomerase activity of hepatoma cells and its relationship with replication of hepatitis B virus]
[Effects of differentially expressed proteins in hepatocellular carcinoma cell treated by different telomerase inhibitors]
[Effects of hTERT RNAi on apoptosis of hepatocellular carcinoma cells induced by TRAIL]
[Expression and clinical significance of telomerase hTRT in primary hepatocellular carcinoma]
[Expressions of h-TERT, c-myc, PCNA and cell apoptosis in liver carcinogenesis]
[Inhibition of telomerase activity by ribozyme targeted to human telomerase transcriptase]
[Inhibitory effect of lentivirus-mediated hTERTp-TK combined with hTERTp-tumstatin on human hepatocarcinoma HepG2 cells].
[Inhibitory effect of RNAi targeting human telomerase reverse transcriptase against human hepatocellular carcinoma cells]
[Mechanisms of human telomerase reverse transcriptase RNAi which increases hepatocellular carcinoma cell apoptosis induced by TRAIL]
[Progress on prevention and treatment of Chinese medicine to molecular mechanism of liver cancer]
[Studies on telomerase reverse transcriptase components and liver cancer].
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
[Telomerase activity in liver cancer and the adjacent tissue]
[Telomerase activity inhibition and apoptosis induction of BEL-7404 human hepatoma cells by antisense oligonucleotides to telomerase RNA component]
[Telomere length and telomerase activity in hepatocellular carcinoma]
[The correlation analysis of telomerase activity and aberrant expression of telomerase subunits during the progression of hepatocellular carcinoma]
[The relationship between gene polymorphism of telomerase reverse transcriptase and susceptibility to hepatocellular carcinoma].
[Usefulness of telomerase activity in the diagnosis of small hepatocellular carcinoma]
Carcinoma, Intraductal, Noninfiltrating
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
Characterization of ductal carcinoma in situ cell lines established from breast tumor of a Singapore Chinese patient.
Culture models of human mammary epithelial cell transformation.
Expression of telomerase genes in cancer development in atypical hyperplasia of the mammary duct.
Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ.
Preoperative diagnosis of intraductal papillary-mucinous tumors of the pancreas with attention to telomerase activity.
Telomerase activity in ductal carcinoma in situ and invasive breast cancer.
Telomerase activity in ductal carcinoma in situ of the breast.
Telomerase activity in human proliferative breast lesions.
Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome.
Telomerase activity in normal and neoplastic breast.
Telomerase activity in the human breast.
[Expression of telomerase genes in mamary atypical ductal hyperplasia]
[Relationship between expressions of telomerase genes and apoptosis related genes in mammary ductal atypical hyperplasia]
Carcinoma, Islet Cell
Mouse models for the study of telomerase.
Carcinoma, Lewis Lung
High expression of circadian gene mPer2 diminishes radiosensitivity of tumor cells.
Carcinoma, Medullary
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.
Telomerase activity in benign and malignant thyroid diseases.
Telomerase activity in thyroid malignancy.
Carcinoma, Merkel Cell
Telomerase activity of Merkel cell carcinomas and Merkel cell carcinoma-derived cell cultures.
Carcinoma, Mucoepidermoid
Increased telomerase activity and hTERT expression in human salivary gland carcinomas.
Telomerase activity in oral cancer.
[PTEN tumor suppressor gene combined with doxycycline inhibites telomerase activity in human mucoepidermoid carcinoma cell line].
Carcinoma, Neuroendocrine
Lack of telomerase activity in lung carcinoids is dependent on human telomerase reverse transcriptase transcription and alternative splicing and is associated with long telomeres.
Carcinoma, Non-Small-Cell Lung
A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer.
Analysis of mutant p53 and telomerase activity in non-small cell lung cancer.
Analysis of spontaneous tumor-specific CD4 T cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response.
Association of p53 gene mutation and telomerase activity in resectable non-small cell lung cancer.
BIBR1532, a Selective Telomerase Inhibitor, Enhances Radiosensitivity of Non-Small Cell Lung Cancer Through Increasing Telomere Dysfunction and ATM/CHK1 Inhibition.
Case-Control Study on Impact of the Telomerase Reverse Transcriptase Gene Polymorphism and Additional Single Nucleotide Polymorphism (SNP)- SNP Interaction on Non-Small Cell Lung Cancers Risk in Chinese Han Population.
Chidamide-induced ROS accumulation and miR-129-3p-dependent cell cycle arrest in non-small lung cancer cells.
Circulating DNA is a useful prognostic factor in patients with advanced non-small cell lung cancer.
Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical trial.
Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer.
Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer.
Combination of multiple gene markers to detect circulating tumor cells in the peripheral blood of patients with non-small cell lung cancer using real-time PCR.
Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.
Correlation between telomerase expression and terminal restriction fragment length ratio in non-small cell lung cancer--an adjusted measurement and its clinical significance.
Detecting cell-free circulating hTERT mRNA in the plasma may identify a subset of nonsmall cell lung cancer patients.
Detection of circulating carcinoma cells by telomerase activity.
Detection of human telomerase reverse transcriptase mRNA in cells obtained by lavage of the pleura is not associated with worse outcome in patients with stage I/II non-small cell lung cancer: Results from Cancer and Leukemia Group B 159902.
Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer.
Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model.
Discriminating association of a common telomerase reverse transcriptase promoter polymorphism with telomere parameters in non-small cell lung cancer with or without epidermal growth factor receptor mutation.
Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
Elevation of telomerase activity positively correlates to poor prognosis of patients with non-small cell lung cancer.
Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter--effect on telomerase expression and telomere length maintenance in non-small cell lung cancer.
Expression of telomerase hTERT in human non-small cell lung cancer and its correlation with c-myc gene.
Expression of telomeric repeat binding factor 1 protein in nonsmall cell lung cancer with human telomerase reverse transcriptase positive.
Genetic Polymorphism, Telomere Biology and Non-Small Lung Cancer Risk.
Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance.
Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination.
In vitro activation of hTERT-specific T cell responses in lung cancer patients following chemotherapy.
Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell lung cancer.
Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells.
Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells.
Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer.
LncRNA MEG3 inhibits non-small cell lung cancer via interaction with DKC1 protein.
Long-Term Outcomes of a Phase I Study With UV1, a Second Generation Telomerase Based Vaccine, in Patients With Advanced Non-Small Cell Lung Cancer.
Modulation of telomere shelterin by TRF1 [corrected] and TRF2 interacts with telomerase to maintain the telomere length in non-small cell lung cancer.
Molecular staging of lung cancer: real-time polymerase chain reaction estimation of lymph node micrometastatic tumor cell burden in stage I non-small cell lung cancer--preliminary results of Cancer and Leukemia Group B Trial 9761.
MYC and human telomerase gene (TERC) copy number gain in early-stage non-small cell lung cancer.
Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
Optimized tumor cryptic peptides: the basis for universal neo-antigen-like tumor vaccines.
P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment.
Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity.
Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation.
Prevalence of telomerase activity in human cancer.
Prognostic impact of telomerase activity in non-small cell lung cancers.
Prognostic significance of telomerase activity and some tumor markers in non-small cell lung cancer.
Prognostic significance of telomerase polymorphism in non-small cell lung cancer.
Quantification in the serum of the catalytic fraction of reverse telomerase: a useful prognostic factor in advanced non-small cell lung cancer.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Real-time RT-PCR quantification of human telomerase reverse transcriptase splice variants in tumor cell lines and non-small cell lung cancer.
RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer.
Telomerase activity and Bcl-2 expression in non-small cell lung cancer.
Telomerase activity and expression of the telomerase catalytic subunit gene in non-small cell lung cancer: correlation with decreased apoptosis and clinical prognosis.
Telomerase activity and serum levels of p53 protein as prognostic factors of survival in patients with advanced non-small cell lung cancer.
Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer.
Telomerase activity in endoscopically visible lung cancer.
Telomerase activity in non-small cell lung cancer.
Telomerase activity in transthoracic fine-needle biopsy aspirates from non-small cell lung cancer as prognostic factor of patients' survival.
Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner.
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial.
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer.
Telomerase-Mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance.
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status.
Telomere shortening is associated with poor prognosis and telomerase activity correlates with DNA repair impairment in non-small cell lung cancer.
The level of telomere dysfunction determines the efficacy of telomerase-based therapeutics in a lung cancer cell line.
Vorinostat represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells.
[Expression and significance of telomerase reverse transcriptase and its regulators in non-small cell lung carcinoma]
[Expression of multidrug resistance-associated gene in non-small cell lung cancer and its correlations with telomerase reverse transcriptase and genes related to apoptosis]
[Influence of nicotine addiction on telomerase activity in malignant non-small cell lung tumors]
[Relationship among telomerase activity, telomerase RNA and telomerase catalytic subunit gene expression and their significance in non small-cell lung cancer]
[Telomerase activity in human non-small cell lung cancer (NSCLC)]
[The Expression of hTERT mRNA and p16 Protein in Non-small Cell Lung Cancer.]
Carcinoma, Ovarian Epithelial
Alteration of telomerase activity associated with development and extension of epithelial ovarian cancer.
Alteration of telomerase activity in ovarian cancer after chemotherapy.
Bmi-1 siRNA inhibited ovarian cancer cell line growth and decreased telomerase activity.
Correlation of Bmi-1 expression and telomerase activity in human ovarian cancer.
Correlations of BMI-1 expression and telomerase activity in ovarian cancer tissues.
Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer.
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
Induction of ovarian cancer cell apoptosis by 1,25-dihydroxyvitamin D3 through the down-regulation of telomerase.
RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression.
Telomerase activity in human ovarian carcinoma.
Telomerase activity in sex cord-stromal tumors of the ovary.
Telomerase activity in the female reproductive tract and neoplasms.
The role of telomerase activity in predicting early recurrence of epithelial ovarian cancer after first-line chemotherapy: a prospective clinical study.
Vascular endothelial growth factor (VEGF) expression and survival in human epithelial ovarian carcinomas.
Carcinoma, Pancreatic Ductal
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Semi-quantitative analysis of telomerase in pancreatic ductal adenocarcinoma.
Telomerase elevation in pancreatic ductal carcinoma compared to nonmalignant pathological states.
[The role of telomerase for pancreatic carcinogenesis in human and hamster]
Carcinoma, Papillary
Expression of Epstein-Barr virus in thyroid carcinoma correlates with tumor progression.
Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms.
Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension.
Telomerase activity in benign and malignant human thyroid tissues.
Telomerase activity in benign and malignant thyroid tumors.
Telomerase activity in human thyroid carcinomas originating from the follicular cells.
Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid.
Telomerase activity in thyroid malignancy.
Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.
Carcinoma, Renal Cell
Antisense wnt-5a mimics wnt-1-mediated C57MG mammary epithelial cell transformation.
Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology.
Augmented telomerase activity, reduced telomere length and the presence of alternative lengthening of telomere in renal cell carcinoma: Plausible predictive and diagnostic markers.
BCG effects on telomerase activity in bladder cancer cell lines.
Determination of telomerase activity for differential analysis of multifocal renal cell carcinomas.
Determination of telomerase activity in multifocal renal cell carcinoma.
Differential expression of full-length telomerase reverse transcriptase mRNA and telomerase activity between normal and malignant renal tissues.
Ectopic expression of wnt-5a in human renal cell carcinoma cells suppresses in vitro growth and telomerase activity.
Emerging immunotherapeutic strategies targeting telomerases in genitourinary tumors.
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
Genetic changes and telomerase activity in human renal cell carcinoma.
High telomerase activity correlates with the stabilities of genome and DNA ploidy in renal cell carcinoma.
hTERT expression in sporadic renal cell carcinomas.
Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma.
Human telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment.
Human telomerase RNA expression and MIB-1 (Ki-67) proliferation index distinguish hemangioblastomas from metastatic renal cell carcinomas.
Immunohistochemical expression of proliferative markers in renal cell carcinoma.
Inhibition of proliferation and induction of apoptosis in human renal carcinoma cells by anti-telomerase small interfering RNAs.
Inhibition of telomerase activity in renal cell carcinoma cells by doxorubicin and anti-Fas monoclonal antibody.
Loss of heterozygosity at chromosome 3p correlates with telomerase activity in renal cell carcinoma.
Low frequency of positive telomerase activity in a chromophobe subtype of renal cell carcinoma.
Modulation of telomerase activity by zinc in human prostatic and renal cancer cells.
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Quantitative analysis of telomerase activity and telomerase reverse transcriptase expression in renal cell carcinoma.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Renal cell carcinoma (RCC) and telomerase activity: relationship to stage.
Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence.
Role of vaccine therapy for renal cell carcinoma in the era of targeted therapy.
Sarcomatoid Renal Cell Carcinoma With Unusual Metastasis to the Small Intestine Manifesting as Perforated Appendicitis.
Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics.
Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element.
Telomerase activity and telomere length in different areas of renal cell carcinoma.
Telomerase activity and telomere lengths: alterations in renal cell carcinomas.
Telomerase activity in human renal cell carcinoma.
Telomerase activity in malignant and benign renal tumors.
Telomerase activity in renal cell carcinoma by modified telomeric repeat amplification protocol assay.
Telomerase activity in renal cell carcinoma.
Telomerase pulsed dendritic cells for immunotherapy for renal cell carcinoma.
Telomere shortening in renal cell carcinoma.
TERT promoter mutations in clear cell renal cell carcinoma.
The opposing effect of hypoxia-inducible factor-2alpha on expression of telomerase reverse transcriptase.
Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase 1/2 trial.
Wilms' tumour 1 can suppress hTERT gene expression and telomerase activity in clear cell renal cell carcinoma via multiple pathways.
[Expression of human telomerase reverse transcriptase in renal cell carcinoma and its clinical significance]
Carcinoma, Small Cell
Evidence for elevated telomerase activity in small cell carcinoma of the bladder.
Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas.
Telomerase activity in small cell esophageal carcinoma.
Carcinoma, Squamous Cell
Allelotype and loss of heterozygosity around the L-myc gene locus in primary lung cancers.
Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma.
Antiproliferative effects of celecoxib in Hep-2 cells through telomerase inhibition and induction of apoptosis.
Azacitidine, as a DNMT inhibitor decreases hTERT gene expression and telomerase activity more effective compared with HDAC inhibitor in human Head and neck squamous cell carcinoma cell lines.
Biological behavior of keratoacanthoma and squamous cell carcinoma: telomerase activity and COX-2 as potential markers.
Biological features of bronchial squamous dysplasia followed up by autofluorescence bronchoscopy.
Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.
Change of telomerase activity in peripheral blood of patients with head and neck squamous cell carcinoma pre and post curative treatment.
Change of telomerase activity in peripheral whole blood of head and neck squamous cell carcinoma patients before and after surgery: a pilot study.
Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer.
Clinical significance of telomerase activity in peripheral blood of patients with esophageal squamous cell carcinoma.
Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus.
Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy.
Comparative analysis of various tumor-associated antigen-specific t-cell responses in patients with hepatocellular carcinoma.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors.
Detection of HPV E7 Oncoviral Protein in Cervical Lesions by a New Antibody.
Detection of telomerase activity in esophageal squamous cell carcinoma and normal esophageal epithelium.
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Detection of telomerase activity in oral lesions.
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Determination of telomerase activity in squamous cell carcinoma of the penis.
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours.
Differing Expression of Cytokines and Tumor Markers in Combined Pulmonary Fibrosis and Emphysema Compared to Emphysema and Pulmonary Fibrosis.
Dissemination of cancer cells into circulation occurs by incisional biopsy of oral squamous cell carcinoma.
Dyskeratosis Congenita and Oral Cavity Squamous Cell Carcinoma: Report of a Case and Literature Review.
Effects of resveratrol on the proliferation, apoptosis and telomerase ability of human A431 epidermoid carcinoma cells.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
EGFR Tyrosine Kinase Inhibitor Pelitinib Regulates Radiation-Induced p65-Dependent Telomerase Activation in Squamous Cell Carcinoma.
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase.
Evaluation of telomerase in non-melanoma skin cancer.
Expression of human telomerase reverse transcriptase in vulvar intraepithelial neoplasia and squamous cell carcinoma: an immunohistochemical study with survivin and p53.
Expression of telomerase components in oral keratinocytes and squamous cell carcinomas.
Expression of VEGF, HGF, IL-6, IL-8, MMP-9, Telomerase in Peripheral Blood of Patients with Head and Neck Squamous Cell Carcinoma.
Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4.
Gene expression of telomerase related proteins in human normal oral and ectocervical epithelial cells.
High levels of telomere dysfunction bestow a selective disadvantage during the progression of human oral squamous cell carcinoma.
Human squamous cell carcinomas lose a mortality gene from chromosome 6q14.3 to q15.
Human telomerase reverse transcriptase is a promising target for cancer inhibition in squamous cell carcinomas.
Human telomerase reverse transcriptase regulates cyclin D1 and G1/S phase transition in laryngeal squamous carcinoma.
ICAM-5 (telencephalin) gene expression in head and neck squamous carcinoma tumorigenesis and perineural invasion!
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung.
Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells.
Inhibition of telomerase activity as a measure of tumor cell killing by cisplatin in squamous cell carcinoma cell line.
Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells.
Intact functional domains of the retinoblastoma gene product (pRb) are required for downregulation of telomerase activity.
Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32.
Localization of telomerase hTERT protein and hTR in benign mucosa, dysplasia, and squamous cell carcinoma of the cervix.
MART-10, a novel vitamin D analog, inhibits head and neck squamous carcinoma cells growth through cell cycle arrest at G0/G1 with upregulation of p21 and p27 and downregulation of telomerase.
Mechanism of telomerase repression during terminal differentiation of normal epithelial cells and squamous carcinoma lines.
miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.
Mouse models for the study of telomerase.
Negative Prognostic Implication of TERT Promoter Mutations in Human Papillomavirus-Negative Tonsillar Squamous Cell Carcinoma Under the New 8th AJCC Staging System.
Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.
Non-steroidal anti-inflammatory drugs inhibit telomerase activity in head and neck squamous carcinoma cell lines.
Oesophageal basaloid squamous cell carcinoma: a unique clinicopathological entity with telomerase activity as a prognostic indicator.
P53 expression, p53 and Ha-ras mutation and telomerase activation during nitrosamine-mediated hamster pouch carcinogenesis.
Predictive and prognostic significance of telomerase levels/telomere length in tissues and peripheral blood in head and neck squamous cell carcinoma.
Prevalence of telomerase activity in human cancer.
Promoter region mutations of the telomerase reverse transcriptase (TERT) gene in head and neck squamous cell carcinoma.
Quantification of alternative splicing variants of human telomerase reverse transcriptase and correlations with telomerase activity in lung cancer.
Quantification of telomerase activity of regions unstained with iodine solution that surround oral squamous cell carcinoma.
Quantitative assay of telomerase activity in head and neck squamous cell carcinoma and other tissues.
Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas.
Radiation enhances suicide gene therapy in radioresistant laryngeal squamous cell carcinoma via activation of a tumor-specific promoter.
Radiation-induced effects on telomerase in gynecological cancer cell lines with different radiosensitivity and repair capacity.
Radio-activation of hTERT promoter in larynx squamous carcinoma cells: an 'indirected-activator' strategy in radio-gene-therapy.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix.
Resistance to telomerase inhibition by human squamous cell carcinoma cell lines.
Retinoic acid suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma.
RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.
Simultaneous over activation of EGFR, telomerase (h TERT), and cyclin D1 correlates with advanced disease in larynx squamous cell carcinoma: a tissue microarray analysis.
Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113).
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Telomerase activation in cervical neoplasia.
Telomerase activity and expression of telomerase genes in squamous dysplasia and squamous cell carcinoma of the esophagus.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity during carcinogenesis in the bronchus.
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA.
Telomerase activity in cervical intraepithelial neoplasia.
Telomerase activity in esophageal squamous cell carcinoma and lesions unstained with Lugol's solution.
Telomerase activity in giant condyloma acuminatum.
Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.
Telomerase activity in head and neck tumors after introduction of wild-type p53, p21, p16, and E2F-1 genes by means of recombinant adenovirus.
Telomerase activity in human laryngeal squamous cell carcinomas.
Telomerase activity in Indian patients with carcinomas of the aerodigestive tract.
Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma.
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Telomerase activity in the female reproductive tract and neoplasms.
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.
Telomerase activity in the vaginal margins of radical hysterectomy in patients with carcinoma of the cervix: correlation with histology and human papillomavirus.
Telomerase activity levels in the surgical margin and tumour distant tissue of the squamous cell carcinoma of the head-and-neck.
Telomerase activity of peripheral blood mononuclear cells from patients with laryngeal carcinoma.
Telomerase activity, telomere length, and apoptosis: a comparison between acquired cholesteatoma and squamous cell carcinoma.
Telomerase as an independent prognostic factor in head and neck squamous cell carcinoma.
Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study.
Telomerase catalytic subunit in laryngeal carcinogenesis--an immunohistochemical study.
Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix.
Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Telomerase hTR and hTRT gene expression in oral precancerous lesions and squamous cell carcinomas.
Telomerase inhibition alters telomere maintenance mechanisms in laryngeal squamous carcinoma cells.
Telomerase inhibition decreases esophageal squamous carcinoma cell migration and invasion.
Telomerase reverse transcriptase mediates EMT through NF-?B signaling in tongue squamous cell carcinoma.
Telomerase, cervical cancer, and human papillomavirus.
Telomere Dysfuction Promotes Metastasis in a TERC Null Mouse Model of Head and Neck Cancer.
Telomere shortening in mucosa surrounding the tumor: biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell carcinoma.
Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma.
Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.
TERT promoter hotspot mutations and their relationship with TERT levels and telomere erosion in patients with head and neck squamous cell carcinoma.
TERT promoter mutation in patients with second primary of tongue squamous cell carcinoma.
TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.
TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma.
TERT promoter mutations in periocular carcinomas: implications of ultraviolet light in pathogenesis.
The consequences of insulin-like growth factors/receptors dysfunction in lung cancer.
The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation.
The influence of reactivation of the telomerase in tumour tissue on the prognosis of squamous cell carcinomas in the head and neck.
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization.
Ultrastructural immunolocalization of telomerase and hyaluronate in migrating keratinocytes in a case of oro-pharyngeal squamous cancer.
[Actinic keratoses]
[Correlations of telomere length and telomerase activity to radiosensitivity of human laryngeal squamous carcinoma cells]
[Detection and effect of telomerase activity in oral mucosal squamous cell carcinoma]
[Detection of telomerase activity in laryngeal carcinoma and the association between telomerase activity and lymphatic metastasis]
[Effect of bufalin on cellular proliferation and apoptosis in human esophageal squamous carcinoma EC9706 cells].
[Expression of telomerase reverse transcriptase and its relationship with expression of c-myc in laryngeal squamous cell carcinomas]
[Expression of telomerase reverse transcriptase in premalignant esophageal squamous dysplasia]
[Genic alterations in oral and head and neck squamous cell carcinomas: analysis of international literature]
[Quantitative assay of telomerase activity in head and neck squamous cell carcinoma]
[Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck]
[Relationship among HPV16 infection and Expression of hTERT, p21waf1, Ki67 in cervical intraepithelial neoplasias and squamous cell carcinomas of cervix uteri]
[Relationship between human papillomavirus 16 infection and the expression of p33(ING1b), human telomerase reverse transcriptase in cervical squamous cell carcinoma of Uygur female in Xinjiang Uygur Autonomous Region]
[Research on expression of telomerase hTR gene in oral precancerous lesion and squamous cell carcinoma]
[Short hairpin RNA silencing of vascular endothelial growth factor, telomerase reverse transcriptase, and Bcl-xl expression in human laryngeal squamous carcinoma xenografted in nude mice]
[Telomerase activity in esophageal carcinoma and lesions unstained with Lugol's solution]
[Telomerase activity in human head and neck squamous cell carcinoma and adjacent tissues]
[Telomerase activity of tumors in the head and neck]
[Telomerase SiRNA inhibits KB cell growth in human oral squamous cell carcinoma.]
[The effect of telomerase inhibitors on oral squamous carcinoma cells]
[The effects on expressions of p53 and PCNA by inhibition of hTERT with siRNA in transplantable model of human laryngeal squamous carcinoma in nude mice]
[The expressions of telomerase activity and cyclinD1 protein in laryngeal squamous cell carcinoma]
[The study on the role of telomerase activity in human nasopharyngeal carcinoma]
Carcinoma, Transitional Cell
A novel tumor-specific gene therapy for bladder cancer.
A prospective evaluation of the diagnostic and potential prognostic utility of urinary human telomerase reverse transcriptase mRNA in patients with bladder cancer.
Combined assay of CYFRA21-1, telomerase and vascular endothelial growth factor in the detection of bladder transitional cell carcinoma.
Correlation of expression of CD44 isoforms and E-cadherin with differentiation in human urothelial cell lines and transitional cell carcinoma.
Evaluation of an in vitro telomeric repeat amplification protocol assay to detect telomerase activity in canine urine.
Expression of telomerase catalytic subunit (hTERT) mRNA does not predict survival in patients with transitional cell carcinoma of the upper urinary tract.
Expression of telomerase mRNA component (hTR) in transitional cell carcinoma of the upper urinary tract.
Genetic changes and telomerase activity in human renal cell carcinoma.
New quinolones, ofloxacin and levofloxacin, inhibit telomerase activity in transitional cell carcinoma cell lines.
Semi-quantitative analysis of telomerase activity in exfoliated human urothelial cells and bladder transitional cell carcinoma.
Semi-quantitative analysis of telomerase activity in human urothelial cells and bladder transitional cell carcinoma.
Significant telomere reduction in human superficial transitional cell carcinoma.
Telomerase activity and cytokeratin 20 as markers for the detection and followup of transitional cell carcinoma: an unfulfilled promise.
Telomerase activity in patients with transitional cell carcinoma: a preliminary study.
Telomerase activity in solid transitional cell carcinoma, bladder washings, and voided urine.
Telomerase activity: a biomarker of cell proliferation, not malignant transformation.
Telomerase activity: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes.
Carcinoma, Verrucous
Determination of telomerase activity in squamous cell carcinoma of the penis.
Cardiomegaly
Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden.
Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats.
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart.
Cardiomyopathies
Association of genetic variation in telomere-related SNP and telomerase with ventricular arrhythmias in ischemic cardiomyopathy.
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.
Cardiomyopathy with mitochondrial damage associated with nucleoside reverse-transcriptase inhibitors.
Cardiomyopathy, nucleoside reverse transcriptase inhibitors and mitochondria are linked through AIDS and its therapy.
Cardiotropic viruses in the myocardium of children with end-stage heart disease.
Direct, DNA pol-gamma-independent effects of nucleoside reverse transcriptase inhibitors on mitochondrial bioenergetics.
Mitochondrial DNA impairment in nucleoside reverse transcriptase inhibitor-associated cardiomyopathy.
Mitochondrial DNA replication, nucleoside reverse-transcriptase inhibitors, and AIDS cardiomyopathy.
Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients - Potential markers of ventricular arrhythmia.
Cardiomyopathy, Alcoholic
Evaluation of Myocyte Proliferation in Alcoholic Cardiomyopathy: Telomerase Enzyme Activity (TERT) Compared with Ki-67 Expression.
Cardiomyopathy, Dilated
Early and late effects of cardiac resynchronization therapy on force-frequency relation and contractility regulating gene expression in heart failure patients.
Cardiotoxicity
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
Telomerase therapy attenuates cardiotoxic effects of doxorubicin.
Cardiovascular Diseases
Association between abacavir exposure and increased risk for cardiovascular disease in patients with human immunodeficiency virus.
Atorvastatin Therapy Modulates Telomerase Activity in Patients Free of Atherosclerotic Cardiovascular Diseases.
Differential Regulation of Telomerase Reverse Transcriptase Promoter Activation and Protein Degradation by Histone Deacetylase Inhibition.
Exercise Modulates Oxidative Stress and Inflammation in Aging and Cardiovascular Diseases.
Exercise, telomerase activity, and cardiovascular disease prevention.
Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.
HDL slowing down endothelial progenitor cells senescence: a novel anti-atherogenic property of HDL.
Increased telomerase activity and comprehensive lifestyle changes: a pilot study.
Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review.
Prognostic Association of TERC, TERT Gene Polymorphism, and Leukocyte Telomere Length in Acute Heart Failure: A Prospective Study.
Quantitative telomerase activity in circulating human leukocytes: utility of real-time telomeric repeats amplification protocol (RQ-TRAP) in a clinical/epidemiological setting.
Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.
Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.
Telomerase as a Therapeutic Target in Cardiovascular Disease.
Telomere biology and cardiovascular disease.
Telomere length and telomerase activity in the context of menopause.
Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients - Potential markers of ventricular arrhythmia.
Telomeres and Telomerase in Cardiovascular Diseases.
Telomeres and telomerase in risk assessment of cardiovascular diseases.
Telomeres and telomerase in the fetal origins of cardiovascular disease: a review.
Telomeres as Therapeutic Targets in Heart Disease.
The effects of aspirin and N-3 fatty acids on telomerase activity in adults with diabetes mellitus.
The role of the terc-63g>a and tert-1327c>t telomerase polymorphisms in the study of men with acute coronary syndrome.
[CLINICAL CASE: THE SIDE EFFECTS OF STATINS].
Cataract
Biomarkers of Oxidative Stress and Cataract. Novel Drug Delivery Therapeutic Strategies Targeting Telomere Reduction and the Expression of Telomerase Activity in the Lens Epithelial Cells with N -Acetylcarnosine Lubricant Eye Drops: Anti-Cataract which Helps to Prevent and Treat Cataracts in the Eyes of Dogs and other Animals.
Biomarkers of oxidative stress and cataract. novel drug delivery therapeutic strategies targeting telomere reduction and the expression of telomerase activity in the lens epithelial cells with N-acetylcarnosine lubricant eye drops: anti-cataract which helps to prevent and treat cataracts in the eyes of dogs and other animals.
Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Telomerase activity in lens epithelial cells of normal and cataractous lenses.
Cell Transformation, Neoplastic
PP2A: the expected tumor suppressor.
Spontaneous neoplastic regression: the significance of apoptosis.
Telomerase activity: a biomarker of cell proliferation, not malignant transformation.
Central Nervous System Diseases
The Emerging Roles for Telomerase in the Central Nervous System.
Central Nervous System Infections
Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus.
Central Nervous System Neoplasms
Meningiomas, dicentric chromosomes, gliomas, and telomerase activity.
Telomerase activity in Malaysian patients with central nervous system tumors.
Cerebrovascular Disorders
Aspirin inhibits human telomerase activation in unstable carotid plaques.
Cervical Intraepithelial Neoplasia
Accuracy of telomerase in cervical lesions: a systematic review.
Cervical intraepithelial neoplasia: Telomerase activity and splice pattern of hTERT mRNA.
Detection of HPV E7 Oncoviral Protein in Cervical Lesions by a New Antibody.
Detection of human telomerase RNA gene in cervical cancer and precancerous lesions: comparison with cytological and human papillomavirus DNA test findings.
Detection of telomerase, its components, and human papillomavirus in cervical scrapings as a tool for triage in women with cervical dysplasia.
Different amplification patterns of the human telomerase RNA gene in invasive cervical carcinomas and cervical intraepithelial neoplasia grade III.
Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions.
Effect of acetic acid on telomerase activity in cervical intraepithelial neoplasia.
Gain of human telomerase RNA gene is associated with progression of cervical intraepithelial neoplasia grade I or II.
Gain of the human telomerase RNA gene TERC at 3q26 is strongly associated with cervical intraepithelial neoplasia and carcinoma.
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.
Genomic amplification patterns of human telomerase RNA gene and C-MYC in liquid-based cytological specimens used for the detection of high-grade cervical intraepithelial neoplasia.
Human Telomerase Gene and High-Risk Human Papillomavirus Infection are Related to Cervical Intraepithelial Neoplasia.
Human telomerase RNA component (hTERC) gene expression and chromosome 7 ploidy correlate positively with histological grade of cervical intraepithelial neoplasia.
Human telomerase RNA gene amplification detection increases the specificity of cervical intraepithelial neoplasia screening.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Predictive role of telomerase activity in the clinical outcome of patients with benign lesions of the uterine cervix or CIN.
Prospective study of hTERC gene detection by fluorescence in situ hybridization (FISH) in cervical intraepithelial neoplasia 1 natural prognosis.
Telomerase activation in cervical neoplasia.
Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears.
Telomerase activity as a tumor marker in Indian women with cervical intraepithelial neoplasia and cervical cancer.
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA.
Telomerase activity in cervical intraepithelial neoplasia.
Telomerase activity in gynecological tumors.
Telomerase activity, MIB-1, PCNA, HPV 16 and p53 as diagnostic markers for cervical intraepithelial neoplasia.
Telomerase and human papillomavirus as diagnostic adjuncts for cervical dysplasia and carcinoma.
Telomerase and markers of cellular proliferation are associated with the progression of cervical intraepithelial neoplasia lesions.
Telomerase assay and HPV 16/18 typing as adjunct to conventional cytological cervical cancer screening.
Telomerase in (pre)neoplastic cervical disease.
Upregulation of telomerase (hTERT) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus, virus persistence, or disease outcome in cervical cancer.
[Amplification and clinical significance of hTERC gene in the cervical exfoliated cells from natural population in Shenzhen]
[Application of Van-Clear and xylene in the detection of cervical hTERC gene by fluorescence in situ hybridization].
[Expression of human telomerase reverse transcriptase in cervix cancer and its significance]
[Study on the correlation between the different papillomavirus type and telomerase in cervical cancer]
[Telomerase activity in cervical cancer and its precursor lesion]
[Telomerase activity in cervical carcinoma and cervical intraepithelial neoplasia and its correlation to classification of koilocytosis]
[Telomerase activity in cervical intraepithelial neoplasia]
Chagas Disease
Biochemical properties of Trypanosoma cruzi telomerase.
Chemical and Drug Induced Liver Injury
Drug-induced liver injury associated with the use of nonnucleoside reverse-transcriptase inhibitors.
Cholangiocarcinoma
Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy.
Cholangiocarcinoma: recent progress. Part 2: molecular pathology and treatment.
Circulating hTERT mRNA as a tumor marker in cholangiocarcinoma patients.
Detection of telomerase activity in biopsy specimens for diagnosis of biliary tract cancers.
Detection of telomerase activity in exfoliated cancer cells obtained from bile.
Detection of telomerase reverse transcriptase mRNA in biopsy specimens and bile for diagnosis of biliary tract cancers.
Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
Hepatitis B virus X gene induces human telomerase reverse transcriptase mRNA expression in cultured normal human cholangiocytes.
High promoter activity of cytokeratin-19 gene in cholangiocarcinoma.
In situ detection of TGF betas, TGF beta receptor II mRNA and telomerase activity in rat cholangiocarcinogenesis.
In situ nucleic acid detection of human telomerase in intrahepatic cholangiocarcinoma and its preneoplastic lesion.
Increased telomerase activity in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Interleukin-6 decreases senescence and increases telomerase activity in malignant human cholangiocytes.
Malignant transformation of the cultured human normal biliary tract epithelial cells induced by hepatitis C virus core protein.
Selection of tumour specific promoters for adenoviral gene therapy of cholangiocarcinoma.
Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity is repressed during differentiation along the hepatocytic and biliary epithelial lineages: verification on immortal cell lines from the same origin.
Telomerase reactivation is associated with hepatobiliary and pancreatic cancers.
Upregulation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells.
[Detection of telomerase activity of exfoliated cells in bile and its clinical impact]
Cholangitis
Detection of telomerase activity in exfoliated cancer cells obtained from bile.
Cholecystitis
Detection of telomerase activity in exfoliated cancer cells obtained from bile.
[The systems of molecular genetic markers under cancer of stomach].
Cholelithiasis
Telomerase activation--one step on the road to carcinoma of the gall bladder.
[Detection of telomerase activity of exfoliated cells in bile and its clinical impact]
Cholesteatoma
Expression of telomerase activity in cholesteatoma otitis media.
Expression patterns of Ki-67 and telomerase activity in middle ear cholesteatoma.
Molecular biological diagnosis of congenital and acquired cholesteatoma on the basis of differences in telomere length.
Telomerase activity and cell proliferation index in cholesteatoma.
Telomerase activity, telomere length, and apoptosis: a comparison between acquired cholesteatoma and squamous cell carcinoma.
[Expression and significance of TERT and c-Myc oncogene protein product on cholesteatoma epithelium]
Cholesteatoma, Middle Ear
Expression patterns of Ki-67 and telomerase activity in middle ear cholesteatoma.
[Expression and significance of TERT and c-Myc oncogene protein product on cholesteatoma epithelium]
Chondroma
Chondrosarcoma is not characterized by detectable telomerase activity.
Recurrent 12q13-15 chromosomal aberrations, high frequency of isocitrate dehydrogenase 1 mutations, and absence of high mobility group AT-hook 2 expression in periosteal chondromas.
Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy.
Chondromatosis, Synovial
Telomerase activity in the synovial tissues of chronic inflammatory and non-inflammatory rheumatic diseases.
Chondrosarcoma
Chondrosarcoma is not characterized by detectable telomerase activity.
Consequences of telomerase inhibition by BIBR1532 on proliferation and chemosensitivity of chondrosarcoma cell lines.
hTERT promoter mutations in chondrosarcomas associate with progression and disease-related mortality.
Malignant transformation in human chondrosarcoma cells supported by telomerase activation and tumor suppressor inactivation.
Telomerase Activation in Malignant Bone Tumors.
Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy.
TERT promoter mutation is an objective clinical marker for disease progression in chondrosarcoma.
Chordoma
Association of telomerase expression with recurrence of sacral chordoma.
Chordoma of the skull base: predictors of tumor recurrence.
Cytogenetic, telomere, and telomerase studies in five surgically managed lumbosacral chordomas.
Establishing tumor cell lines from aggressive telomerase-positive chordomas of the skull base. Technical note.
Prognostic significance of hTERT (human telomerase reverse transcriptase) promoter region mutations C228T and C250T for overall survival in spinal chordomas.
Upregulated human telomerase reverse transcriptase (hTERT) expression is associated with spinal chordoma growth, invasion and poor prognosis.
Choriocarcinoma
Activation of telomerase in BeWo cells by estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin in co-operation with c-Myc.
Activation of Toll-like receptor 5 decreases the attachment of human trophoblast cells to endometrial cells in vitro.
All-trans retinoic acid (atra) inhibits telomerase expression of BeWo choriocarcinoma cell (ATCC CCL-98).
Comparison of telomerase activity in normal chorionic villi to trophoblastic diseases.
Effect of human telomerase reverse transcriptase transfection on differentiation in BeWo choriocarcinoma cells.
Estrogen and progesterone receptors and telomerase enzyme immunohistochemical detection in gestational trophoblastic tumors.
Galectin signature of the choriocarcinoma JAr cells: Galectin-1 as a modulator of invasiveness in vitro.
Nuclear telomerase is less accessible to antibody probing than known nuclear antigens: retrieval with new immunostaining buffer.
Telomerase activity in complete hydatidiform mole.
Telomerase activity in gestational trophoblastic disease.
Telomerase activity in gynecological tumors.
[Telomerase RNA antisense oligonucleotides inhibit growth of human choriocarcinoma xenograft in nude mice]
Choroidal Neovascularization
Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice.
Chronic Periodontitis
Evaluation of telomerase expression in chronic periodontitis.
Telomerase Expression in Subjects With Chronic and Aggressive Periodontitis.
Chronobiology Disorders
The protective effect of cycloastragenol on aging mouse circadian rhythmic disorder induced by d-galactose.
Classical Swine Fever
Assessing the value of PCR assays in oral fluid samples for detecting African swine fever, classical swine fever, and foot-and-mouth disease in U.S. swine.
Cleft Lip
Association between CLPTM1L-TERT rs401681 polymorphism and pancreatic cancer risk among Chinese Han population.
Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population.
Genetic polymorphisms in the TERT-CLPTM1L region and lung cancer susceptibility in Chinese males.
Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer-A case-control study in a Chinese population.
Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer: a case-control study in northeast Chinese male population.
Genetic polymorphisms of TERT and CLPTM1L, cooking oil fume exposure, and risk of lung cancer: a case-control study in a Chinese non-smoking female population.
Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma.
Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in a Chinese population.
Polymorphisms of TERT and CLPTM1L and the risk of hepatocellular carcinoma in Chinese males.
Rs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis.
Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population.
Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients.
Coinfection
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection.
Do type and duration of antiretroviral therapy attenuate liver fibrosis in HIV-hepatitis C virus-coinfected patients?
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study.
Formation of lentivirus particles by mammalian cells infected with recombinant fowlpox virus.
Hepatic steatosis and HIV infection.
HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection.
Predictive factors of lopinavir/ritonavir discontinuation for drug-related toxicity: results from a cohort of 416 multi-experienced HIV-infected individuals.
Replication of adeno-associated virus type 2 in human lymphocytic cells and interaction with HIV-1.
Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitors.
[Interaction of gag polyprotein-precursors p55 and p48 with p160gag-pol during formation of virus-like particles of HIV-1 with recombinant strains of vaccinia virus]
Colitis
Acetylsalicylic acid treatment improves differentiation and immunomodulation of SHED.
Activation of the cannabinoid 2 receptor (CB(2)) protects against experimental colitis.
Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer.
The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey.
Colitis, Ulcerative
Clinical usefulness of telomerase for the detection of colon cancer in ulcerative colitis patients.
Deficiency of colonic telomerase in ulcerative colitis.
Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis.
Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases.
Kimura's disease associated with ulcerative colitis: detection of IL-5 mRNA expression of peripheral blood mononuclear cells and colon lesion.
Motilin receptor expression in smooth muscle, myenteric plexus, and mucosa of human inflamed and noninflamed intestine.
Phenotypical and functional study of ghrelin and its receptor in the pathogenesis of Crohn's disease.
Telomerase activity in chronic inflammatory bowel disease.
Telomerase activity in long-standing ulcerative colitis.
Telomere dysfunction instigates inflammation in inflammatory bowel disease.
[Insulin-like growth factor receptor, hepatocyte-derived growth factor receptor and telomerase expression in ulcerative colitis]
Colonic Neoplasms
6-Dithio-2'-deoxyguanosine analogs induce reactive oxygen species-mediated tumor cell apoptosis via bi-targeting thioredoxin 1 and telomerase.
A novel magnetic bead-based assay with high sensitivity and selectivity for analysis of telomerase in exfoliated cells from patients with bladder and colon cancer.
Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients.
An overview on red algae bioactive compounds and their pharmaceutical applications.
Antisense telomerase induced cell growth inhibition, cell cycle arrest and telomerase activity down-regulation in gastric and colon cancer cells.
Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence.
BRCA2 Deletion Induces Alternative Lengthening of Telomeres in Telomerase Positive Colon Cancer Cells.
Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer.
Clinical usefulness of telomerase for the detection of colon cancer in ulcerative colitis patients.
Clinical utility of telomerase in cancer.
Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line.
CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells.
Cytological diagnosis and telomerase activity of cells in effusions of body cavities.
Cytotoxic effect of Rosa canina extract on human colon cancer cells through repression of telomerase expression.
Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis.
Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.
Detection of circulating carcinoma cells by telomerase activity.
Differences in telomerase activity and the effects of AZT in aneuploid and euploid cells in colon cancer.
Differences in telomerase activity between colon and rectal cancer.
Downregulation of EphA1 in colorectal carcinomas correlates with invasion and metastasis.
Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells.
Downregulation of telomerase activity by diclofenac and curcumin is associated with cell cycle arrest and induction of apoptosis in colon cancer.
Editorial retraction. Down-regulation of human telomerase reverse transcriptase through anti-c-myc siRNA in human colon cancer Colo 320 cells.
Effect of antisense oligodeoxynucleotide of telomerase RNA on telomerase activity and cell apoptosis in human colon cancer.
Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro.
Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines.
Effects of various agents on DNA fragmentation and telomerase enzyme activities in adenocarcinoma cell lines.
Efficiency of diagnostic biomarkers among colonic schistosomiasis Egyptian patients.
Evaluation of telomerase in the development and progression of colon cancer.
Evaluation of telomerase mRNA (hTERT) in colon cancer.
Expression of T-STAR gene is associated with regulation of telomerase activity in human colon cancer cell line HCT-116.
Genome editing through large insertion leads to the skipping of targeted exon.
Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells.
Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation.
Influence of antitumor drugs on the expression of Fas system in SW480 colon cancer cells.
Interaction between survivin and aurora-B kinase plays an important role in survivin-mediated up-regulation of human telomerase reverse transcriptase expression.
Interleukin 8 is a biomarker of telomerase inhibition in cancer cells.
Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival ?1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells.
Mechanisms for inhibition of colon cancer cells by sulforaphane through epigenetic modulation of microRNA-21 and human telomerase reverse transcriptase (hTERT) down-regulation.
Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse.
Morus Rubra Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells Through Endoplasmic Reticulum Stress and Telomerase.
Nonradioisotopic telomeric repeat amplification protocol (TRAP) using digoxigenin labeled probe.
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network, in colon cancer cells.
Purification and characterization of a novel lectin with antiphytovirus activities from the wild mushroom Paxillus involutus.
Quantification of somatic mutation flow across individual cell division events by lineage sequencing.
Quantitative analysis of hTERT mRNA expression in colorectal cancer.
Retraction: siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells.
Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines.
Sentinel lymph node mapping technique in colon cancer.
SERS assay of telomerase activity at single-cell level and colon cancer tissues via quadratic signal amplification.
Silencing of the hTERT gene by shRNA inhibits colon cancer SW480 cell growth in vitro and in vivo.
siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells.
Survivin enhances telomerase activity via up-regulation of specificity protein 1- and c-Myc-mediated human telomerase reverse transcriptase gene transcription.
Synthesis, biological evaluation, drug-likeness, and in silico screening of novel benzylidene-hydrazone analogues as small molecule anticancer agents.
Tamoxifen and gonadal steroids inhibit colon cancer growth in association with inhibition of thymidylate synthase, survivin and telomerase expression through estrogen receptor beta mediated system.
Telomerase activity and cell apoptosis in colon cancer cell by human telomerase reverse transcriptase gene antisense oligodeoxynucleotide.
Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues.
Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer.
Telomerase inhibition using azidothymidine in the HT-29 colon cancer cell line.
Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells.
Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition.
The Australian fruit Illawarra plum (Podocarpus elatus Endl., Podocarpaceae) inhibits telomerase, increases histone deacetylase activity and decreases proliferation of colon cancer cells.
The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.
Understanding the Interplay between COX-2 and hTERT in Colorectal Cancer Using a Multi-Omics Analysis.
Walnut phenolic extracts reduce telomere length and telomerase activity in a colon cancer stem cell model.
[Clinical significance of human telomerase reverse transcriptase in patients with colon cancer]
[Detection of telomerase activity and its clinical significance in colonic cancers by PCR-ELISA]
[Effects of matrine on proliferation and telomerase activity of colon cancer SW1116 cells]
[Experimental study of NK4 gene targeted therapy mediated by human telomerase reverse transcriptase promoter for colon cancer].
[Expression of telomerase genes in human tumors]
[The effect of As2O3 on induction of apoptosis and inhibition of telomerase activity in colon cancer LS-174T cells]
Colorectal Neoplasms
A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants.
A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-?B inactivation in colorectal cancer cells.
A Rare Variant P507L in TPP1 Interrupts TPP1-TIN2 Interaction, Influences Telomere Length, and Confers Colorectal Cancer Risk in Chinese Population.
Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers.
Antisense telomerase induced cell growth inhibition, cell cycle arrest and telomerase activity down-regulation in gastric and colon cancer cells.
Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk.
Aurora kinase expression in colorectal adenocarcinoma: correlations with clinicopathological features, p16 expression, and telomerase activity.
Berberine Inhibits Telomerase Activity and Induces Cell Cycle Arrest and Telomere Erosion in Colorectal Cancer Cell Line, HCT 116.
Blackberry Extract Inhibits Telomerase Activity in Human Colorectal Cancer Cells.
Bufalin Inhibits hTERT Expression and Colorectal Cancer Cell Growth by Targeting CPSF4.
Change in telomerase activity during human colorectal carcinogenesis.
Changes in telomerase activity due to alternative splicing of human telomerase reverse transcriptase in colorectal cancer.
Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells.
Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer.
Clinical usefulness of telomerase activity and telomere length in the preoperative diagnosis of gastric and colorectal cancer.
Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis.
Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma.
Correlative polymorphism of NAD(P)H: quinone oxidoreductase (NQO1) with telomere shortening in colorectal cancer.
CXCR4 as a novel predictive biomarker for metastasis and poor prognosis in colorectal cancer.
Cytotoxic T-cell immunity against telomerase reverse transcriptase in colorectal cancer patients.
Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization.
Detection of cancer cells in mesenteric vein and peripheral vessels by measuring telomerase activity in patients with colorectal cancer.
Detection of colorectal cancer cells in peripheral blood by reverse-transcriptase polymerase chain reaction for cytokeratin 20.
Detection of telomerase activity in biopsy samples of colorectal cancer.
Determining the telomerase activity of exfoliated cells in intestinal lavage solution to detect colorectal carcinoma.
Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model.
Does the presence of circulating tumor cells in the venous drainage of curative colorectal cancer resections determine prognosis? A meta-analysis.
Down-regulation of Inositol Polyphosphate 4-Phosphatase Type II Expression in Colorectal Carcinoma.
Downregulation of EphA1 in colorectal carcinomas correlates with invasion and metastasis.
Downregulation of telomerase activity by diclofenac and curcumin is associated with cell cycle arrest and induction of apoptosis in colon cancer.
Early detection of peritoneal dissemination of gastrointestinal cancers by reverse-transcriptase polymerase chain reaction.
Effect of penclomedine (NSC-338720) on telomere fusions, chromatin blebbing, and cell viability with and without telomerase activity and abrogated p53 function.
Effects of phosphorothioate anti-sense oligodeoxynucleotides on colorectal cancer cell growth and telomerase activity.
Evaluation of telomerase in the development and progression of colon cancer.
Evaluation of telomerase mRNA (hTERT) in colon cancer.
Exosomal miR-1255b-5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial-to-mesenchymal transition.
Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
Ginger: is it ready for prime time?
High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer.
hTERT gene copy number is not associated with hTERT RNA expression or telomerase activity in colorectal cancer.
hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells.
hTERT Promotes CRC Proliferation and Migration by Recruiting YBX1 to Increase NRF2 Expression.
Human telomerase reverse transcriptase (hTERT) is a target gene of ?-catenin in human colorectal tumors.
Human telomerase reverse transcriptase expression in colorectal tumors: correlations with immunohistochemical expression and clinicopathologic features.
Human telomerase reverse transcriptase recruits the ?-catenin/TCF-4 complex to transactivate chemokine (C-C motif) ligand 2 expression in colorectal cancer.
Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.
Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation.
Induction of telomerase activity and chromosome aberrations in human tumour cell lines following X-irradiation.
Inhibition on LS-174T cell growth and activity of telomerase in vitro and in vivo by arsenic trioxide.
Keratin 23 promotes telomerase reverse transcriptase expression and human colorectal cancer growth.
Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro study.
Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.
Micrometastases and survival in stage II colorectal cancer.
MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer.
Molecular biology of colorectal cancer.
Novel Prognostic Biomarkers in Metastatic and Locally Advanced Colorectal Cancer: Micronuclei Frequency and Telomerase Activity in Peripheral Blood Lymphocytes.
PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation.
Penclomedine-induced DNA fragmentation and p53 accumulation correlate with reproductive cell death in colorectal carcinoma cells with altered p53 status.
PinX1 without the G-patch motif suppresses proliferation, induces senescence, but does not inhibit telomerase activity in colorectal cancer SW480 cells.
Polymerase chain reaction-based enzyme immunoassay for quantitation of telomerase activity: application to colorectal cancers.
Possible role of telomerase activation in the cancer predisposition of patients with hereditary nonpolyposis colorectal cancers.
Prevalence of telomerase activity in human cancer.
Prognostic potential of the telomerase subunit human telomerase reverse transcriptase in tumor tissue and nontumorous mucosa from patients with colorectal carcinoma.
Proinflammatory Cytokines IL-6 and TNF-? Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells.
Promoter methylation correlates with reduced NDRG2 expression in advanced colon tumour.
Quantification of telomerase activity in sporadic colorectal carcinoma: association with tumor growth and venous invasion.
Quantitative analysis of hTERT mRNA expression in colorectal cancer.
Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma.
Re: Cancer cells in mesenteric vein and peripheral vessels by measuring telomerase activity in patients with colorectal cancer.
Real time quantification in plasma of human telomerase reverse transcriptase (hTERT) mRNA in patients with colorectal cancer.
Real-time PCR quantification of human telomerase reverse transcriptase (hTERT) in colorectal cancer.
Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells.
Regulation of telomerase and its hTERT messenger in colorectal cancer.
Relationship between microsatellite instability and telomere shortening in colorectal cancer.
Relative contribution of normal and neoplastic cells determines telomerase activity and telomere length in primary cancers of the prostate, colon, and sarcoma.
Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells.
Screening and preliminary validation of miRNAs with the regulation of hTERT in colorectal cancer.
Semi-quantitative procedure for telomeric repeat amplification protocol (TRAP) assay in colorectal carcinomas.
Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Study of the role of telomerase in colorectal cancer: preliminary report and literature review.
Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line.
Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo.
Telomerase activation without shortening of telomeric 3'-overhang is a poor prognostic factor in human colorectal cancer.
Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma.
Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer.
Telomerase activity and human telomerase reverse transcriptase expression in colorectal carcinoma.
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
Telomerase activity and p53 gene mutation in familial polyposis coli.
Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence.
Telomerase activity as a prognostic factor in colorectal cancer.
Telomerase activity associated with acquisition of malignancy in human colorectal cancer.
Telomerase activity in colorectal cancer and its relationship to bcl-2 expression.
Telomerase activity in colorectal cancer, prognostic factor and implications in the microsatellite instability pathway.
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Telomerase activity in stage II colorectal carcinoma.
Telomerase activity is a prognostic factor for recurrence and survival in rectal cancer.
Telomerase activity is commonly detected in hereditary nonpolyposis colorectal cancers.
Telomerase activity of blood samples and recurrence of colorectal cancer.
Telomerase activity significantly correlates with cell differentiation, proliferation and lymph node metastasis in colorectal carcinomas.
Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer.
Telomerase as a diagnostic and predictive marker in colorectal carcinoma.
Telomerase expression as a predictive marker of radiotherapy response in rectal cancer.
Telomerase expression of malignant epithelial cells correlates with Dukes' stage in colorectal cancer.
Telomerase inhibition as a potential new therapy for colorectal cancer.
Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.
Telomerase inhibition using azidothymidine in the HT-29 colon cancer cell line.
Telomerase is an independent prognostic marker of overall survival in patients with colorectal cancer.
Telomerase Reverse Transcriptase (TERT) Gene Variations and Susceptibility of Colorectal Cancer.
Telomerase subunit immunoreactivity and recurrence in colorectal cancer.
Telomerase: a target for colorectal cancer treatment?
Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.
Telomere function in colorectal cancer.
Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma.
Telomere length changes in colorectal cancers and polyps.
Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer.
Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas.
Telomeres and telomerase in the clinical management of colorectal cancer.
Telomeres, telomerase and colorectal cancer.
The association between telomerase, p53, and clinical staging in colorectal cancer.
The HIV reverse transcriptase inhibitor Tenofovir suppressed DMH/HFD-induced colorectal cancer in Wistar rats.
The prognostic value of hTERT expression levels in advanced-stage colorectal cancer patients: a comparison between tissue and serum expression.
The Relationship between Telomerase Activity and Clinicopathological Parameters in Colorectal Cancer: A Meta-Analysis.
TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer.
Understanding the Interplay between COX-2 and hTERT in Colorectal Cancer Using a Multi-Omics Analysis.
Upregulation of mtSSB by interleukin-6 promotes cell growth through mitochondrial biogenesis-mediated telomerase activation in colorectal cancer.
[Detection of telomerase activity in intestinal lavage solution from colorectal carcinoma patients]
[Diagnostic significance of telomerase activity and telomere length in endoscopic sample of colorectal cancer]
[Study of telomerase activity in colorectal carcinomas]
[Suppression of cell growth in colorectal cancer by inhibition of telomerase]
[Telomerase activity and genomic instability in colorectal cancers]
[Telomerase activity in colorectal cancer--a semi-quantitative procedure]
[Telomerase activity in colorectal carcinoma and its relationship to clinicopathological findings]
[Telomerase activity in human gastric and colorectal cancer]
[Telomerase activity in stool of patients with colorectal cancer]
[The effect of As2O3 on induction of apoptosis and inhibition of telomerase activity in colon cancer LS-174T cells]
Colorectal Neoplasms, Hereditary Nonpolyposis
A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants.
Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome.
Telomerase activity is commonly detected in hereditary nonpolyposis colorectal cancers.
Communicable Diseases
Approved Antiviral Drugs over the Past 50 Years.
HIV-1 subtype characteristics of infected persons living in southwestern Greece.
Condylomata Acuminata
Increased telomerase activity and decreased telomere length in genital condylomata acuminata.
Confusion
Improved methods and standards for telomerase detection: quantitative histopathology using antibody staining.
Congenital Abnormalities
Risk of birth defects and perinatal outcomes in HIV-infected women exposed to integrase strand inhibitors during pregnancy.
Congenital Bone Marrow Failure Syndromes
Constitutional telomerase mutations are genetic risk factors for cirrhosis.
Nopp140-mediated concentration of telomerase in Cajal bodies regulates telomere length.
Posterior pharyngeal wall squamous cell carcinoma arising in a patient with dyskeratosis congenita.
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.
The effect of TERC haploinsufficiency on the inheritance of telomere length.
Conjunctivitis
Respiratory syncytial virus may be a pathogen in allergic conjunctivitis.
Connective Tissue Diseases
Telomerase activity in connective tissue diseases: elevated in rheumatoid arthritis, but markedly decreased in systemic sclerosis.
Telomerase activity in peripheral blood mononuclear cells of systemic connective tissue diseases.
Coronary Artery Disease
Activation of telomerase and expression of human telomerase reverse transcriptase in coronary atherosclerosis.
Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.
Diet and Dermatology: The Role of a Whole-food, Plant-based Diet in Preventing and Reversing Skin Aging-A Review.
ISH ADA-01 Critical role of telomerase in regulating cerebral vascular function and redox environment.
Lipid profiles associated with antiretroviral drug choices.
Potential associations of testosterone/estradiol ratio, leukocyte hTERT expression and PBMC telomerase activity with aging and the presence of coronary artery disease in men.
Telomerase, telomere length, and coronary artery calcium in black and white men in the CARDIA study.
The predictive role of circulating telomerase and vitamin D for long-term survival in patients undergoing coronary artery bypass grafting surgery (CABG).
The role of the terc-63g>a and tert-1327c>t telomerase polymorphisms in the study of men with acute coronary syndrome.
Coronary Disease
Does antiretroviral therapy increase or decrease the risk of cardiovascular disease?
Impact of nucleoside reverse transcriptase inhibitors on coronary heart disease.
Lack of causal relationship between leukocyte telomere length and coronary heart disease.
Coronavirus Infections
SARS-associated viral hepatitis caused by a novel coronavirus: report of three cases.
Cough
Prevalence and clinical features of pneumonia in patients with laboratory-confirmed pandemic influenza A H1N1 2009 infection in South Korea.
COVID-19
A Case of Covid-19 Patient with Acute Limb Ischemia and Heparin Resistance.
A cluster-control approach to a coronavirus disease 2019 (COVID-19) outbreak on a stroke ward with infection control considerations for dementia and vascular units.
A Danish population-based case series of patients with liver cirrhosis and coronavirus disease 2019.
A human-computer collaboration for COVID-19 differentiation: combining a radiomics model with deep learning and human auditing.
A single-center, retrospective study of COVID-19 features in children: a descriptive investigation.
Age, neutrophil lymphocyte ratio, and radiographic assessment of the quantity of lung edema (RALE) score to predict in-hospital mortality in COVID-19 patients: a retrospective study.
Antibody response after one and two jabs of the BNT162b2 vaccine in nursing home residents: The CONsort-19 study.
Antigen-based rapid diagnostic testing or alternatives for diagnosis of symptomatic COVID-19: A simulation-based net benefit analysis.
Association between chronic ACE inhibitor exposure and decreased odds of severe disease in patients with COVID-19.
Clinical features and disease severity in an Iranian population of inpatients with COVID-19.
Clinical performance of the Panbio assay for the detection of SARS-CoV-2 IgM and IgG in COVID-19 patients.
Clinical presentation and outcomes of the first patients with COVID-19 in Argentina: Results of 207079 cases from a national database.
Clinical Profiles and Outcomes of COVID-19 in Kidney Transplant Recipients: Experience From a High-Volume Public Sector Transplant Center in India.
Clinical significance of prognostic nutrition index in hospitalized patients with COVID-19: Results from single-center experience with systematic review and meta-analysis.
Comparison of outcomes in HIV-positive and HIV-negative patients with COVID-19.
COVID-19 Carrier or Pneumonia: Positive Real-Time Reverse-Transcriptase Polymerase Chain Reaction but Negative or Positive Chest CT Results.
COVID-19 In-Hospital Mortality and Use of Renin-Angiotensin System Blockers in Geriatrics Patients.
COVID-19 Pulmonary Infection with Pneumothorax in a Young Patient.
COVID-19 Stroke Apical Lung Examination Study: A Diagnostic and Prognostic Imaging Biomarker in Suspected Acute Stroke.
Efficacy of a Test-Retest Strategy in Residents and Health Care Personnel of a Nursing Home Facing a COVID-19 Outbreak.
Epidemiological and clinical characteristics of 214 families with COVID-19 in Wuhan, China.
Evaluation of a comprehensive pre-procedural screening protocol for COVID-19 in times of a high SARS CoV-2 prevalence: a prospective cross-sectional study.
Evaluation of commercially available immuno-magnetic agglutination in comparison to enzyme-linked immunosorbent assays for rapid point-of-care diagnostics of COVID-19.
Evaluation of healthcare personnel exposures to patients with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) associated with personal protective equipment.
Evaluation of sample collection and transport strategies to enhance yield, accessibility, and biosafety of COVID-19 RT-PCR testing.
Evaluation of sample treatments in a safe and straightforward procedure for the detection of SARS-CoV-2 in saliva.
Evidence of the presence of SARS-CoV-2 virus in atmospheric air and surfaces of a dedicated COVID hospital.
Expanding molecular diagnostic capacity for COVID-19 in Ethiopia: operational implications, challenges and lessons learnt.
Extracellular Vesicles and Citrullinated Histone H3 in Coronavirus Disease 2019 Patients.
False negative rate of COVID-19 PCR testing: a discordant testing analysis.
False-Negative Nasopharyngeal Swab RT-PCR Assays in Typical COVID-19: Role of Ultra-low-dose Chest CT and Bronchoscopy in Diagnosis.
Frailty and Mortality in Hospitalized Older Adults With COVID-19: Retrospective Observational Study.
Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID-19 patients.
Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region.
Intriguing Antiviral Modified Nucleosides: A Retrospective View into the Future Treatment of COVID-19.
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Novel Coronavirus Disease (COVID-19) in Italian Patients: Gender Differences in Presentation and Severity.
Pregnancy outcomes among symptomatic and asymptomatic women infected with COVID-19 in the west of Iran: a case-control study.
Prevalence of positive COVID-19 among asymptomatic health care workers who care patients infected with the novel coronavirus: A retrospective study.
Prospective Comparison of Saliva and Nasopharyngeal Swab Sampling for Mass Screening for COVID-19.
Rapid Antigen Test Combined with Chest Computed Tomography to Rule Out COVID-19 in Patients Admitted to the Emergency Department.
Reverse-transcriptase polymerase chain reaction versus chest computed tomography for detecting early symptoms of COVID-19. A diagnostic accuracy systematic review and meta-analysis.
Role of CT angiography in detecting acute pulmonary embolism associated with COVID-19 pneumonia.
Salivette, a relevant saliva sampling device for SARS-CoV-2 detection.
Sample collection and transport strategies to enhance yield, accessibility, and biosafety of COVID-19 RT-PCR testing.
SARS Cov2 outbreak management on a landing helicopter dock: An observational retrospective study.
Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Stability issues of RT-PCR testing of SARS-CoV-2 for hospitalized patients clinically diagnosed with COVID-19.
Stroke in patients with SARS-CoV-2 infection: case series.
Successful treatment of 28 patients with coronavirus disease 2019 at a medical center in Taiwan.
Tenofovir, Another Inexpensive, Well-Known and Widely Available Old Drug Repurposed for SARS-COV-2 Infection.
The clinical manifestations and interval changes of reverse-transcriptase quantitative polymerase chain reactions among different specimens of coronavirus disease 2019 patients.
The Cumulative Rate of SARS-CoV-2 Infection in Chinese Hemodialysis Patients.
The Importance of Chest CT Scan in COVID-19.
The optimal diagnostic methods for COVID-19.
The prognostic value of myocardial injury in COVID-19 patients and associated characteristics.
The Usefulness of Chest CT Imaging in Patients With Suspected or Diagnosed COVID-19: A Review of Literature.
Tomographic score (RAD-Covid Score) to assess the clinical severity of the novel coronavirus infection.
Umifenovir treatment is not associated with improved outcomes in patients with coronavirus disease 2019: a retrospective study.
Underperformance of Reverse-Transcriptase Polymerase Chain Reaction in Japan and Potential Implications From Diamond Princess Cruise Ship and Other Countries During the Ongoing COVID-19 Pandemic.
Update on the diagnosis and management of COVID-19 in pediatric patients.
Validation of saliva sampling as an alternative to oro-nasopharyngeal swab for detection of SARS-CoV-2 using unextracted rRT-PCR with the Allplex 2019-nCoV assay.
Value of standard echocardiography at the bedside for COVID-19 patients in intensive care units: a Japanese single-center analysis.
[Oro- and nasopharyngeal swab for detection of SARS-CoV-2 - step-by-step approach].
[Oro- and Nasopharyngeal Swab for Detection of SARS-CoV-2 - Step-by-step Approach].
Cowpox
Genetic stability of recombinant MVA-BN.
Craniopharyngioma
Craniopharyngiomas, including Recurrent Cases, Lack TERT Promoter Hotspot Mutations.
Cri-du-Chat Syndrome
Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndrome.
Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.
Crohn Disease
Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases.
Lymphocyte telomere dynamics and telomerase activity in inflammatory bowel disease: effect of drugs and smoking.
MDR1 mRNA expressions in peripheral blood mononuclear cells of patients with ulcerative colitis in relation to glucocorticoid administration.
Motilin receptor expression in smooth muscle, myenteric plexus, and mucosa of human inflamed and noninflamed intestine.
Phenotypical and functional study of ghrelin and its receptor in the pathogenesis of Crohn's disease.
Telomerase activity in chronic inflammatory bowel disease.
Telomere dysfunction instigates inflammation in inflammatory bowel disease.
Cryptorchidism
Postmeiotic modifications of spermatogenic cells are accompanied by inhibition of telomerase activity.
Cushing Syndrome
[Telomerase expression in various lesions of adrenal cortex]
Cystadenocarcinoma, Mucinous
Telomerase activity is a useful marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts.
Cystadenofibroma
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
Cystadenoma
Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors, and invasive carcinomas.
Biology of ovarian cancer.
Microwave ablation of hepatic cyst: A case report.
Telomerase activity in benign and malignant epithelial ovarian tumors.
Cystadenoma, Mucinous
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
Telomerase activity is a useful marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts.
Cystadenoma, Papillary
Telomerase activity in benign and malignant epithelial ovarian tumors.
Cystadenoma, Serous
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity is a useful marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts.
Cystic Fibrosis
Development of cystic fibrosis and noncystic fibrosis airway cell lines.
Hsp90 and client protein maturation.
Cystitis
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Diagnosis of bladder cancer using telomerase activity in voided urine.
Telomerase activity as a potential marker in preneoplastic bladder lesions.
Telomerase reverse transcriptase (TERT) promoter mutation analysis of benign, malignant and reactive urothelial lesions reveals a subpopulation of inverted papilloma with immortalizing genetic change.
Cysts
A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1.
Cyst Fluid Analysis in Pancreatic Intraductal Papillary Mucinous Neoplasms.
Cyst fluid telomerase activity predicts the histologic grade of cystic neoplasms of the pancreas.
Expression and secretion of CXCL12 are enhanced in autosomal dominant polycystic kidney disease.
IL-4 is protective against development of toxoplasmic encephalitis.
Microaspiration of esophageal gland cells and cDNA library construction for identifying parasitism genes of plant-parasitic nematodes.
Microwave ablation of hepatic cyst: A case report.
Simple Detection of Telomere Fusions in Pancreatic Cancer, Intraductal Papillary Mucinous Neoplasm, and Pancreatic Cyst Fluid.
Transcriptome Characterization of Reverse Development in Turritopsis dohrnii (Hydrozoa, Cnidaria).
Cytomegalovirus Infections
Approved Antiviral Drugs over the Past 50 Years.
Deafness
A C-terminal nonsense mutation links PTPRQ with autosomal-dominant hearing loss, DFNA73.
Deficiency Diseases
Drug discovery for human immunodeficiency virus infection: conquests and hurdles.
Dehydration
Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.
Hypoxia reoxygenation induces premature senescence in neonatal SD rat cardiomyocytes.
Deltaretrovirus Infections
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Dementia
A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity.
Changing incidence of central nervous system diseases in the EuroSIDA cohort.
Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease.
Dynamics of telomerase activity in response to acute psychological stress.
Effects of Meditation and Music-Listening on Blood Biomarkers of Cellular Aging and Alzheimer's Disease in Adults with Subjective Cognitive Decline: An Exploratory Randomized Clinical Trial.
Evidence that aging and amyloid promote microglial cell senescence.
HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir.
Telomere dysfunction of lymphocytes in patients with Alzheimer disease.
Dementia, Vascular
Telomere dysfunction of lymphocytes in patients with Alzheimer disease.
Dengue
A novel method for the preparation of large cDNA fragments from dengue-3 RNA genome by long RT-PCR amplification.
A prospective, multicentre, cohort study to assess the incidence of dengue illness in households from selected communities in Brazil (2014-2018).
Clinical applicability of single-tube multiplex reverse-transcriptase PCR in dengue virus diagnosis and serotyping.
Comparison of reverse-transcriptase qPCR and droplet digital PCR for the quantification of dengue virus nucleic acid.
Dengue Virus Seroprevalence Among Febrile Patients in Bamako, Mali: Results of a 2006 Surveillance Study.
Detection of dengue viral RNA in Aedes aegypti (Diptera: Culicidae) exposed to sticky lures using reverse-transcriptase polymerase chain reaction.
Development of multiplex real-time reverse-transcriptase polymerase chain reaction assay for simultaneous detection of Zika, dengue, yellow fever, and chikungunya viruses in a single tube.
Efficacy of a Tetravalent Dengue Vaccine in Healthy Children and Adolescents.
Incidence of dengue illness in Mexican people aged 6 months to 50 years old: A prospective cohort study conducted in Jalisco.
The comparative accuracy of 8 commercial rapid immunochromatographic assays for the diagnosis of acute dengue virus infection.
Dermatitis
Augmented telomerase activity and reduced telomere length in parthenium-induced contact dermatitis.
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Transgenic rat model of childhood-onset dermatitis by overexpressing telomerase reverse transcriptase (TERT).
Dermatitis, Atopic
Telomerase activity is increased and telomere length shortened in T cells from blood of patients with atopic dermatitis and psoriasis.
Telomerase activity is spontaneously increased in lymphocytes from patients with atopic dermatitis and correlates with cellular proliferation.
Toward a canine model of atopic dermatitis: amplification of cytokine-gene transcripts in the skin of atopic dogs.
Dermatitis, Contact
Augmented telomerase activity and reduced telomere length in parthenium-induced contact dermatitis.
In situ hybridization analysis of the expression of human telomerase RNA in normal and pathologic conditions of the skin.
Dermatitis, Toxicodendron
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Desmoplastic Small Round Cell Tumor
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
Diabetes Mellitus
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Assessment of telomerase activity in leukocytes of type 2 diabetes mellitus patients having or not foot ulcer: Possible correlation with other clinical parameters.
Associations of TERC Single Nucleotide Polymorphisms with Human Leukocyte Telomere Length and the Risk of Type 2 Diabetes Mellitus.
Effects of DHA Supplementation on Vascular Function, Telomerase Activity in PBMC, Expression of Inflammatory Cytokines, and PPAR?-LXR?-ABCA1 Pathway in Patients With Type 2 Diabetes Mellitus: Study Protocol for Randomized Controlled Clinical Trial.
Factors associated with the incidence of type 2 diabetes mellitus in HIV-infected participants in the Swiss HIV Cohort Study.
Novel Neuroendocrine and Metabolic Mechanism Provides the Patented Platform for Important Rejuvenation Therapies: Targeted Therapy of Telomere Attrition and Lifestyle Changes of Telomerase Activity with the Timing of Neuron-Specific Imidazole-Containing Dipeptide-Dominant Pharmaconutrition Provision.
Telomerase deficiency impairs glucose metabolism and insulin secretion.
The effects of aspirin and N-3 fatty acids on telomerase activity in adults with diabetes mellitus.
The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications.
The secrets of telomerase: Retrospective analysis and future prospects.
Diabetes Mellitus, Type 1
Isolation and characterization of stem cells from pancreatic islet: pluripotency, differentiation potential and ultrastructural characteristics.
Diabetes Mellitus, Type 2
Assessment of telomerase activity in leukocytes of type 2 diabetes mellitus patients having or not foot ulcer: Possible correlation with other clinical parameters.
Association study of leukocyte telomere length and genetic polymorphism within hTERT promoter with type 2 diabetes in Bangladeshi population.
Associations of TERC Single Nucleotide Polymorphisms with Human Leukocyte Telomere Length and the Risk of Type 2 Diabetes Mellitus.
Cord blood telomere length, telomerase activity and inflammatory markers in pregnancies in women with diabetes or gestational diabetes.
Effects of DHA Supplementation on Vascular Function, Telomerase Activity in PBMC, Expression of Inflammatory Cytokines, and PPAR?-LXR?-ABCA1 Pathway in Patients With Type 2 Diabetes Mellitus: Study Protocol for Randomized Controlled Clinical Trial.
Factors associated with the incidence of type 2 diabetes mellitus in HIV-infected participants in the Swiss HIV Cohort Study.
MNS16A VNTR polymorphism of human telomerase gene: Elucidation of a gender specific potential allele associated with type 2 diabetes in Bangladeshi population.
The changes of leukocyte telomere length and telomerase activity after sitagliptin intervention in newly diagnosed type 2 diabetes.
The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro.
The effects of aspirin and N-3 fatty acids on telomerase activity in adults with diabetes mellitus.
Diabetes, Gestational
Cord blood telomere length, telomerase activity and inflammatory markers in pregnancies in women with diabetes or gestational diabetes.
Mitochondrial translocation of human telomerase reverse transcriptase in cord blood mononuclear cells of newborns with gestational diabetes mellitus mothers.
Diabetic Angiopathies
The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro.
Diabetic Cardiomyopathies
LncRNA TINCR is downregulated in diabetic cardiomyopathy and relates to cardiomyocyte apoptosis.
The telomere-telomerase axis and the heart.
Diabetic Neuropathies
Overview on pathophysiology and newer approaches to treatment of peripheral neuropathies.
Diabetic Retinopathy
Attenuating Diabetic Vascular and Neuronal Defects by Targeting P2rx7.
Diffuse Intrinsic Pontine Glioma
Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.
Diverticulum
Immunohistochemical detection of telomerase reverse transcriptase in colorectal adenocarcinoma and benign colonic mucosa.
DNA Repair-Deficiency Disorders
Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.
DNA Virus Infections
Emerging antiviral drugs.
Down Syndrome
Development of noninvasive prenatal diagnosis of trisomy 21 by RT-MLPA with a new set of SNP markers.
Role of multiplex reverse-transcriptase PCR for diagnosis of Acute myelosis in an infant with Down's syndrome.
Telomerase and the benign and malignant megakaryoblastic leukemias of Down syndrome.
Telomeres in Trisomy 21 Amniocytes.
Drug Hypersensitivity
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity.
Potent NLRP3 Inflammasome Activation by the HIV Reverse Transcriptase Inhibitor Abacavir.
Drug-Related Side Effects and Adverse Reactions
A transgenic mouse model for HLA-B*57:01-linked abacavir drug tolerance and reactivity.
Chronic binge alcohol consumption does not diminish effectiveness of continuous antiretroviral suppression of viral load in simian immunodeficiency virus-infected macaques.
Direct, DNA pol-gamma-independent effects of nucleoside reverse transcriptase inhibitors on mitochondrial bioenergetics.
Oxidative stress response in telomerase-immortalized fibroblasts from a centenarian.
[Mitochondrial medicine for internists]
[Nucleoside induced hepatopathy in HIV patients. Diagnostic value of liver biopsy assessment]
Dyskeratosis Congenita
A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.
A molecular switch underlies a human telomerase disease.
A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria.
A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish.
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition.
A role for sister telomere cohesion in telomere elongation by telomerase.
A telomerase component is defective in the human disease dyskeratosis congenita.
A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice.
Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment.
Acute depletion of telomerase components DKC1 and NOP10 induces oxidative stress and disrupts ribosomal biogenesis via NPM1 and activation of the P53 pathway.
Anomalous electrophoretic migration of newly synthesized ribosomal RNAs and their precursors from cells with DKC1 mutations.
Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita.
Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.
Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita.
Complex inheritance pattern of dyskeratosis congenita in two families with 2 different mutations in the telomerase reverse transcriptase gene.
Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of Dyskeratosis congenita.
Conformational analysis of the telomerase RNA pseudoknot hairpin by Raman spectroscopy.
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Constitutional telomerase mutations are genetic risk factors for cirrhosis.
Defects in lymphocyte telomere homeostasis contribute to cellular immune phenotype in patients with cartilage-hair hypoplasia.
Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.
Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia.
Development of surface modified biodegradable polymeric nanoparticles to deliver GSE24.2 peptide to cells: A promising approach for the treatment of defective telomerase disorders.
Diagnostics of rare disorders: whole-exome sequencing deciphering locus heterogeneity in telomere biology disorders.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in hoyeraal-hreidarsson syndrome.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndrome.
Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference.
Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita.
Dynamic behavior of the telomerase RNA hairpin structure and its relationship to dyskeratosis congenita.
Dyskeratosis Congenita and Oral Cavity Squamous Cell Carcinoma: Report of a Case and Literature Review.
Dyskeratosis congenita and squamous cell carcinoma of the mandibular alveolar ridge.
Dyskeratosis congenita and telomerase.
Dyskeratosis congenita and the DNA damage response.
Dyskeratosis Congenita Dermal Fibroblasts are Defective in Supporting the Clonogenic Growth of Epidermal Keratinocytes.
Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects.
Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP.
Dyskeratosis congenita, telomeres and human ageing.
Dyskeratosis congenita: advances in the understanding of the telomerase defect and the role of stem cell transplantation.
Dyskeratosis congenita: its link to telomerase and aplastic anaemia.
Dyskeratosis congenita: molecular insights into telomerase function, ageing and cancer.
Dyskeratosis congenita: telomerase, telomeres and anticipation.
Dyskeratosis congenita: the diverse clinical presentation of mutations in the telomerase complex.
Dyskerin ablation in mouse liver inhibits rRNA processing and cell division.
Dyskerin is a component of the arabidopsis telomerase RNP required for telomere maintenance.
Exogenous TERC alone can enhance proliferative potential, telomerase activity and telomere length in lymphocytes from dyskeratosis congenita patients.
Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.
Functional characterization of novel telomerase RNA (TERC) mutations in patients with diverse clinical and pathological presentations.
Genetic instability syndromes with progeroid features.
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells.
GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells.
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita.
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.
Heterozygous telomerase RNA mutations found in dyskeratosis congenita and aplastic anemia reduce telomerase activity via haploinsufficiency.
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita.
Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation.
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.
Lack of mutations of the human telomerase RNA gene (hTERC) in myelodysplastic syndrome.
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA.
Life and Death of Yeast Telomerase RNA.
Limbal stem cell deficiency in patients with inherited stem cell disorder of dyskeratosis congenita.
Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.
Low frequency of telomerase RNA mutations among children with aplastic anemia or myelodysplastic syndrome.
Making the most of a little: dosage effects in eukaryotic telomere length maintenance.
Many disease-associated variants of hTERT retain high telomerase enzymatic activity.
Medical genetics and epigenetics of telomerase.
Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation.
Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita.
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA.
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome.
NOLA1 gene mutations in acquired aplastic anemia.
Nopp140-mediated concentration of telomerase in Cajal bodies regulates telomere length.
PARN modulates Y RNA stability, 3' end formation and its modification.
Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of TERT.
Pigmentary disorders of the eyes and skin.
Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component.
Posterior pharyngeal wall squamous cell carcinoma arising in a patient with dyskeratosis congenita.
Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita.
Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.
Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA component, TERC.
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
Pulmonary fibrosis in dyskeratosis congenita: report of 2 cases.
Regulation of human telomerase in homeostasis and disease.
RETINAL VASCULAR TORTUOSITY AND EXUDATIVE RETINOPATHY IN A FAMILY WITH DYSKERATOSIS CONGENITA MASQUERADING AS FAMILIAL EXUDATIVE VITREORETINOPATHY.
Role of telomeres and telomerase in the pathogenesis of human cancer.
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Short telomeres are sufficient to cause the degenerative defects associated with aging.
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity.
Single-Molecule Analysis of the Human Telomerase RNA.Dyskerin Interaction and the Effect of Dyskeratosis Congenita Mutations.
Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells.
Stem cells, telomerase and dyskeratosis congenita.
Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase.
Telomerase and cancer stem cells.
Telomerase as a clinical target: current strategies and potential applications.
Telomerase dysfunction and dyskeratosis congenita.
Telomerase insufficiency induced telomere erosion accumulation in successive generations in dyskeratosis congenita family.
Telomerase mutations in families with idiopathic pulmonary fibrosis.
Telomerase reverse-transcriptase homozygous mutations in autosomal recessive dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome.
Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes.
Telomerase RNA biosynthesis and processing.
Telomerase RNA deficiency in peripheral blood mononuclear cells in X-linked dyskeratosis congenita.
Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita.
Telomerase RNA levels limit the telomere length equilibrium.
Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation.
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis.
Telomerase RNA structure and function: implications for dyskeratosis congenita.
Telomerase therapeutics for degenerative diseases.
Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells.
Telomere dynamics in induced pluripotent stem cells: Potentials for human disease modeling.
Telomere dysfunction in human diseases: the long and short of it!
Telomere Length and Telomerase Activity Impact the UV Sensitivity Syndrome Xeroderma Pigmentosum C.
Telomere length, stem cells and aging.
Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations.
Telomere maintenance and human bone marrow failure.
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.
Telomeres in health and disease.
Telomeres, p53, HNF4?, and Liver Disease.
Telomeres-structure, function, and regulation.
TERC mutations in children with refractory cytopenia.
TERT and TERC mutations detected in cryptic dyskeratosis congenita suppress telomerase activity.
The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita.
The effect of TERC haploinsufficiency on the inheritance of telomere length.
The impact of dyskeratosis congenita mutations on the structure and dynamics of the human telomerase RNA pseudoknot domain.
The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency.
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita.
The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications.
The role of telomeres in the ageing of human skin.
The Telomerase Complex Directly Controls Hematopoietic Stem Cell Differentiation and Senescence in an Induced Pluripotent Stem Cell Model of Telomeropathy.
TIN2 protein dyskeratosis congenita missense mutants are defective in association with telomerase.
Tissue-specific telomere shortening and degenerative changes in a patient with TINF2 mutation and dyskeratosis congenita.
Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.
Understanding telomere diseases through analysis of patient-derived iPS cells.
YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA.
[Mutation in the telomerase complex component NHP2 in dyskeratosis congenita.]
Dyslipidemias
A study of effect of anti-retroviral therapy regimen on metabolic syndrome in people living with HIV/AIDS: Post hoc analysis from a tertiary care hospital in western India.
Antiretroviral therapy-associated dyslipidemia in patients from a reference center in Brazil.
Dyslipidemia among HIV-infected Patients with tuberculosis taking once-daily nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in India.
Metabolic complications associated with antiretroviral therapy.
Dysplastic Nevus Syndrome
Evaluation of telomerase activity in cutaneous melanocytic proliferations.
Expression of cell cycle and apoptosis regulatory proteins and telomerase in melanocitic lesions.
Telomerase activity in melanocytic lesions: A potential marker of tumor biology.
[The dysplastic nevus. An Ariadne's thread through a conceptual labyrinth]
Dyspnea
Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.
Lactic acidosis and anti-retroviral drugs.
Ectodermal Dysplasia
Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells.
Encephalitis
A retrospective search for lyssavirus in humans in the Northern Territory.
Changing patterns in the neuropathogenesis of HIV during the HAART era.
Evaluation of reverse-transcriptase PCR as a diagnostic tool to confirm Japanese encephalitis virus infection.
Rabies situation in Cambodia.
Encephalitis, Japanese
Evaluation of reverse-transcriptase PCR as a diagnostic tool to confirm Japanese encephalitis virus infection.
Encephalitis, Tick-Borne
A nested RT-PCR for the detection of tick-borne encephalitis virus (TBEV) in ticks in natural foci.
The Langat model for tick-borne encephalitis virus. Specific detection by RT-PCR.
Encephalomyelitis, Eastern Equine
Eastern equine encephalitis in a free-ranging white-tailed deer (Odocoileus virginianus).
End Stage Liver Disease
Liver Transplantation for Decompensated Cirrhosis Secondary to Telomerase Reverse Transcriptase (TERT) Mutation.
Endometrial Hyperplasia
Human telomerase RNA as endogenous control in endometrial tissue.
Immunohistochemical detection of human telomerase reverse transcriptase (hTERT), topoisomerase IIalpha expression, and apoptosis in endometrial adenocarcinoma and atypical hyperplasia.
Implications of telomeres and telomerase in endometrial pathology.
Progesterone receptor expression and proliferative activity in uterine tumours of pet rabbits.
Telomerase activity in gynecologic tumors.
Telomerase and telomere length in normal and malignant human endometrium as prognostic markers.
Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma.
Endometrial Neoplasms
Aberrant Dyskerin Expression Is Related to Proliferation and Poor Survival in Endometrial Cancer.
Alternatively spliced variant deleting exons 7 and 8 of the human telomerase reverse transcriptase gene is dominantly expressed in the uterus.
AMG 479, a Novel IGF-1-R Antibody, Inhibits Endometrial Cancer Cell Proliferation Through Disruption of the PI3K/Akt and MAPK Pathways.
Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells.
Detection of hTERT mRNA in peripheral blood and its implication for diagnosis of early stage postoperative endometrial cancer micrometastasis.
Establishment of an immortalised human ovarian surface epithelial cell line without chromosomal instability.
Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells.
Estrogen-receptor-dependent regulation of telomerase activity in human endometrial cancer cell lines.
Expression of telomerase reverse transcriptase mRNA and its quantitative analysis in human endometrial cancer.
GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells.
Hammerhead ribozymes to modulate telomerase activity of endometrial carcinoma cells.
Herbal complex suppresses telomerase activity in chemo-endocrine resistant cancer cell lines.
Human Endometrial Carcinogenesis Is Associated with Significant Reduction in Long Non-Coding RNA, TERRA.
Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues.
Immunohistochemical detection of human telomerase reverse transcriptase (hTERT), topoisomerase IIalpha expression, and apoptosis in endometrial adenocarcinoma and atypical hyperplasia.
Induction of apoptosis and inhibition of telomerase activity by arsenic trioxide (As2O3) in endometrial carcinoma cells.
Inhibition of telomerase activity in endometrial cancer cells by selenium-cisplatin conjugate despite suppression of its DNA-damaging activity by sodium ascorbate.
Investigating the Role of Telomere and Telomerase Associated Genes and Proteins in Endometrial Cancer.
Is the telomerase assay useful for screening of endometrial lesions?
Knockdown of hTERT and Treatment with BIBR1532 Inhibit Cell Proliferation and Invasion in Endometrial Cancer Cells.
LncRNA-GAS5 induces PTEN expression through inhibiting miR-103 in endometrial cancer cells.
p27, cyclin E, and CDK2 expression in normal and cancerous endometrium.
Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis.
Quantitative analysis of telomerase hTERT mRNA and telomerase activity in endometrioid adenocarcinoma and in normal endometrium.
Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells.
Tamoxifen regulates human telomerase reverse transcriptase (hTERT) gene expression differently in breast and endometrial cancer cells.
Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma.
Telomerase activity in benign endometrium and endometrial carcinoma.
Telomerase activity in gynecological tumors.
Telomerase activity in human endometrium.
Telomerase activity in the female reproductive tract and neoplasms.
Telomerase and telomere length in normal and malignant human endometrium as prognostic markers.
Telomerase and Telomeres in Endometrial Cancer.
Telomerase antisense inhibition for the proliferation of endometrial cancer in vitro and in vivo.
The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels.
[Antisense oligodeoxynucleotides of human telomerase reverse transcriptase inhibit endometrial carcinoma cell HEC-1A proliferation]
[Expression of human telomerase reverse transcriptase and c-myc transcripts in endometrial carcinoma and its precursors]
[Human telomerase P53 estrogen and progesterone receptor expression in endometrial carcinoma]
[Telomerase activity in human primary endometrial carcinoma]
[Telomerase activity in the uterine cervix and the uterine body]
[Telomerase antisense inhibition and chemotherapeutic combination treatments for the proliferation of endometrial cancer in vitro and in vivo]
Endometriosis
Aberrant expression of regulators of cell-fate found in eutopic endometrium is found in matched ectopic endometrium among women and in a baboon model of endometriosis.
Aberrant telomerase expression in the endometrium of infertile women with deep endometriosis.
Creation of immortalised epithelial cells from ovarian endometrioma.
Endometriosis Is Associated with a Significant Increase in hTERC and Altered Telomere/Telomerase Associated Genes in the Eutopic Endometrium, an Ex-Vivo and In Silico Study.
Endometriosis is associated with aberrant endometrial expression of telomerase and increased telomere length.
Endometriosis: a crosstalk between epidermal growth factor (EGF) gene polymorphism and telomerase activity?
Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes.
Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.
Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis.
Implications of telomeres and telomerase in endometrial pathology.
Increased telomerase activity and human telomerase reverse transcriptase mRNA expression in the endometrium of patients with endometriosis.
Is There a Balance in Oxidative-Antioxidant Status in Blood Serum of Patients with Advanced Endometriosis?
Peroxisome proliferator-activated receptor ? agonist suppresses human telomerase reverse transcriptase expression and aromatase activity in eutopic endometrial stromal cells from endometriosis.
Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors.
Endometritis
Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma.
Endotoxemia
Sepsis induces telomere shortening: a potential mechanism responsible for delayed pathophysiological events in sepsis survivors?
Enteritis
Investigating turkey enteric coronavirus circulating in the Southeastern United States and Arkansas during 2012 and 2013.
Enterocolitis, Necrotizing
The effects of IGF-1 and erythropoietin on apoptosis and telomerase activity in necrotizing enterocolitis model.
Enzootic Bovine Leukosis
A reverse transcriptase assay for detection of the bovine leukemia virus.
Characterization of the RNA dependent DNA polymerase of bovine leukemia virus.
Identification of novel singly spliced pX mRNA transcripts common to all human T-cell leukemia virus type 1-related retroviruses.
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Purification and characterization of bovine leukemia virus DNA polymerase.
Thermodynamic stability and statistical significance of potential stem-loop structures situated at the frameshift sites of retroviruses.
[Improved test for the detection of reverse transcriptase of bovine leukosis virus]
[Studies on the virus demonstration in enzootic bovine leukosis using the revertase test]
Eosinophilia
Telomerase activity in Hodgkin's disease.
[Detection of CBF beta-MYH11 fusion transcript and inv(16)(p13;q22) in acute myelomonocytic leukemia(M4) by RT-PCR and FISH]
Ependymoma
Can telomerase activity be unleashed to refine prognosis within ependymoma subgroups?
Expression of telomerase RNA component correlates with the MIB-1 proliferation index in ependymomas.
Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma.
Prognostic significance of telomerase in brain tumors
Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain.
Telomerase expression in gliomas including the nonastrocytic tumors.
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells.
Telomerase Inhibition as a Novel Therapy for Pediatric Ependymoma.
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Telomere maintenance and dysfunction predict recurrence in paediatric ependymoma.
Epidermolysis Bullosa Simplex
Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase.
Epilepsy
In vivo expression of the interleukin 4 receptor alpha by astrocytes in epilepsy cerebral cortex.
Epstein-Barr Virus Infections
Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus.
Epstein-Barr Virus Infection Promotes Epithelial Cell Growth by Attenuating Differentiation-Dependent Exit from the Cell Cycle.
Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma.
hTERT inhibits the Epstein-Barr virus lytic cycle and promotes the proliferation of primary B lymphocytes: implications for EBV-driven lymphomagenesis.
Mechanisms of cell immortalization mediated by EB viral activation of telomerase in nasopharyngeal carcinoma.
Oligonucleotide microarray analysis of gene expression profiles followed by real-time reverse-transcriptase polymerase chain reaction assay in chronic active Epstein-Barr virus infection.
Telomerase activity impacts on Epstein-Barr virus infection of AGS cells.
Equine Infectious Anemia
Characterization of RNA elements that regulate gag-pol ribosomal frameshifting in equine infectious anemia virus.
RNA-dependent DNA polymerase associated with equine infectious anemia virus.
Erectile Dysfunction
Re: Treatment of Diabetes Mellitus-Induced Erectile Dysfunction Using Endothelial Progenitor Cells Genetically Modified with Human Telomerase Reverse Transcriptase.
Telomerase reverse transcriptase genetically modified adipose tissue derived stem cells improves erectile dysfunction by inhibiting oxidative stress and enhancing proliferation in rat model.
Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase.
Erythema
Bowen's disease with high telomerase activity.
Erythema Multiforme
Antiretroviral therapy: effects on orofacial health and health care.
Esophageal Neoplasms
Anti-tumor effects of an oncolytic adenovirus expressing hemagglutinin-neuraminidase of Newcastle disease virus in vitro and in vivo.
Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells.
Azidothymidine inhibits cell growth and telomerase activity and induces DNA damage in human esophageal cancer.
Biology of telomeres: importance in etiology of esophageal cancer and as therapeutic target.
Circulating micrometastases of esophageal cancer detected by carcinoembryonic antigen mRNA reverse transcriptase-polymerase chain reaction: clinical implications.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis.
Establishment of novel human esophageal cancer cell line in relation to telomere dynamics and telomerase activity.
Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions.
Flow cytometric analysis of DNA, telomerase content and multi-gene expression in esophageal epithelial dysplasia.
Genes associated with telomerase activity levels in esophageal carcinoma cell lines.
Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis.
Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32.
Telomerase activity in esophageal squamous cell carcinoma: down-regulation by chemotherapeutic agent.
Telomerase activity measurement in magnetically captured epithelial cells: comparison of slab-gel and capillary electrophoresis.
Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma.
Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks.
Telomere length, telomerase activity and telomerase RNA expression in human esophageal cancer cells: correlation with cell proliferation, differentiation and chemosensitivity to anticancer drugs.
The significance of telomerase activity in cancer lesions and the noncancerous epithelium of the esophagus.
[Effect of nanosize delivery system for ASODN against hTERT on the expression of telomerase in the esophageal cancer EC9706 cells]
[Molecular alterations in esophageal cancer]
[Telomerase activity in esophageal squamous cell carcinoma and in normal esophageal epithelium adjacent to carcinoma]
[Telomerase assay for diagnosis of esophageal cancer]
Esophageal Squamous Cell Carcinoma
Amplification of the telomerase RNA component gene as a new genetic marker for disease progression and prognosis in esophageal squamous cell carcinoma.
Clinical significance of telomerase activity in peripheral blood of patients with esophageal squamous cell carcinoma.
Clinical significance of telomerase activity in the non-cancerous epithelial region of oesophageal squamous cell carcinoma.
Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus.
Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma.
Detection of telomerase activity in esophageal squamous cell carcinoma and normal esophageal epithelium.
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.
Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma.
Expression of cancer testis antigens in head and neck squamous cell carcinomas.
Inhibitory effects of Gleditsia sinensis fruit extract on telomerase activity and oncogenic expression in human esophageal squamous cell carcinoma.
Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Soluble purified recombinant C2ORF40 protein inhibits tumor cell growth in vivo by decreasing telomerase activity in esophageal squamous cell carcinoma.
Telomerase activity analysis of esophageal carcinoma using microdissection-TRAP assay.
Telomerase activity as an indicator of malignant potential in iodine-nonreactive lesions of the esophagus.
Telomerase activity in esophageal squamous cell carcinoma and lesions unstained with Lugol's solution.
Telomerase activity in esophageal squamous cell carcinoma: down-regulation by chemotherapeutic agent.
Telomerase activity of the Lugol-stained and -unstained squamous epithelia in the process of oesophageal carcinogenesis.
Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma.
The inhibitory effect of Gleditsia sinensis on cyclooxygenase-2 expression in human esophageal squamous cell carcinoma.
[Analysis of telomerase activity in esophageal carcinoma using microdissection telomeric repeat amplification protocol assay]
[Expression of telomerase reverse transcriptase in premalignant esophageal squamous dysplasia]
[Telomerase activity in esophageal squamous cell carcinoma and in normal esophageal epithelium adjacent to carcinoma]
Esophagitis, Peptic
Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues.
Essential Hypertension
Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension.
Shorter Leukocyte Telomere Length coupled with lower expression of Telomerase Genes in patients with Essential Hypertension.
[Telomerase activity in peripheral blood leukocytes from patients with essential hypertension]
Esthesioneuroblastoma, Olfactory
Expression of human telomerase reverse transcriptase and cyclin-D1 in olfactory neuroblastoma.
Exanthema
Metabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4.
[Side effects of antiretroviral therapy]
Eye Diseases
Novel Neuroendocrine and Metabolic Mechanism Provides the Patented Platform for Important Rejuvenation Therapies: Targeted Therapy of Telomere Attrition and Lifestyle Changes of Telomerase Activity with the Timing of Neuron-Specific Imidazole-Containing Dipeptide-Dominant Pharmaconutrition Provision.
Fabry Disease
Aging in Fabry Disease: Role of Telomere Length, Telomerase Activity, and Kidney Disease.
Fanconi Anemia
Accelerated telomere shortening and telomerase activation in Fanconi's anaemia.
Fanconi Anemia germline variants as susceptibility factors in aplastic anemia, MDS and AML.
Lack of mutations in the human telomerase RNA component (hTERC) gene in Fanconi's anemia.
Fanconi Syndrome
Fanconi syndrome and lactic acidosis associated with stavudine and lamivudine therapy.
Fasciitis, Necrotizing
Lactic acidosis and hyperlactatemia associated with lamivudine accumulation and sepsis in a kidney transplant recipient-a case report and review of the literature.
Fatigue Syndrome, Chronic
A randomized controlled trial of qigong exercise on fatigue symptoms, functioning, and telomerase activity in persons with chronic fatigue or chronic fatigue syndrome.
Fatty Liver
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance.
High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes.
High doses of stavudine induce fat wasting and mild liver damage without impairing mitochondrial respiration in mice.
Influence of insulin resistance on Hepatic Fibrosis and Steatosis in HCV Monoinfected compared with HIV-HCV co-infected patients.
Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.
Telomerase: a key player in the pathogenesis of non-alcoholic fatty liver disease?
Feline Infectious Peritonitis
Whole blood cytokine profiles in cats infected by feline coronavirus and healthy non-FCoV infected specific pathogen-free cats.
Fetal Death
Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies.
Fetal Growth Retardation
Expression of human telomerase reverse transcriptase and correlation with telomerase activity in placentas with and without intrauterine growth retardation.
Telomerase activity and apoptosis as indicators of ageing in placenta with and without intrauterine growth retardation.
Telomerase and proliferative activity in placenta from women with and without fetal growth restriction.
Telomere homeostasis in IUGR placentas - A review.
TERC telomerase subunit gene copy number in placentas from pregnancies complicated with intrauterine growth restriction.
Fibroadenoma
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
Comparison of Telomere Length and Telomerase Activation between Breast Fibroadenoma and Infiltrating Ductal Carcinoma in Malaysian Women.
Detection of telomerase activity in breast masses by fine-needle aspiration.
Droplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations.
Ets2 transcription factor in normal and neoplastic human breast tissue.
Quantitative analysis of telomerase in feline mammary tissues.
Quantitative determination of telomerase activity in breast cancer and benign breast diseases.
Stromal MED12 exon 2 mutations in complex fibroadenomas of the breast.
Telomerase activation in neoplastic cell immortalization and tumour progression.
Telomerase activity and its inhibition in benign and malignant breast lesions.
Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.
Telomerase activity in human breast tumors.
Telomerase activity in human proliferative breast lesions.
Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma.
Telomerase expression in human breast cancer with and without lymph node metastases.
[Telomerase activity in infiltration ductal carcinoma of breast]
Fibrocystic Breast Disease
Evaluation of telomerase in canine mammary tissues by immunohistochemical analysis and a polymerase chain reaction-based enzyme-linked immunosorbent assay.
[Telomerase activity in infiltration ductal carcinoma of breast]
Fibroma
Establishment of human fibroma cell lines from a MEN1 patient by introduction of either hTERT or SV40 early region.
Genetic determinants of neoplastic diseases induced by a subgroup F avian leukosis virus.
Fibromatosis, Aggressive
Current ideas in desmoid tumours.
Lack of telomerase in desmoids occurring sporadically and in association with familial adenomatous polyposis.
Telomere length and telomerase activity in extra-abdominal desmoid tumors.
Telomere length in familial adenomatous polyposis-associated desmoids.
Fibrosarcoma
An in vitro investigation of immunomodulatory properties of Lactobacillus plantarum and L. delbrueckii cells and their extracellular polysaccharides.
Clinical, histopathological, and molecular analyses of IDH-wild-type WHO grade II-III gliomas to establish genetic predictors of poor prognosis.
Effect of TERT on the growth of fibrosarcoma via caspase-3, survivin and PKB.
Lack of telomerase in desmoids occurring sporadically and in association with familial adenomatous polyposis.
Telomerase activity and metastasis: expansion of cells having higher telomerase activity within culture lines and tumor tissues.
Telomerase activity in melanoma and non-melanoma skin cancer.
Focal Nodular Hyperplasia
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.
Foot Ulcer
Assessment of telomerase activity in leukocytes of type 2 diabetes mellitus patients having or not foot ulcer: Possible correlation with other clinical parameters.
Foot-and-Mouth Disease
Assessing the value of PCR assays in oral fluid samples for detecting African swine fever, classical swine fever, and foot-and-mouth disease in U.S. swine.
[Presence of an RNA dependent DNA polymerase enzyme in the foot-and-mouth disease virus]
Fowlpox
Formation of lentivirus particles by mammalian cells infected with recombinant fowlpox virus.
Randomized, placebo-controlled, phase I/IIa evaluation of the safety and immunogenicity of fowlpox virus expressing HIV gag-pol and interferon-gamma in HIV-1 infected subjects.
Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a 'high-affinity' FcgammaRIIa genotype.
Fragile X Syndrome
High-throughput DNA diagnostic measurements using capillary electrophoresis: p53, fragile X and telomerase.
Furunculosis
Expression of cytokine mRNA in canine anal furunculosis lesions.
Gallbladder Diseases
Prognostic relevance of human telomerase reverse transcriptase (hTERT) expression in patients with gall bladder disease and carcinoma.
Ganglioneuroma
Correlating telomerase activity levels with human neuroblastoma outcomes.
Telomerase activity distinguishes between neuroblastomas with good and poor prognosis.
Gastrinoma
Telomerase activity in pancreatic endocrine tumors.
Gastritis
Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions.
Detection of telomerase activity in gastric lavage fluid: a novel method to detect gastric cancer.
Effect of Helicobacter pylori eradication on oncogenes and cell proliferation.
Helicobacter pylori infection: augmentation of telomerase activity in cancer and noncancerous tissues.
[Telomerase activity in gastric cancer and premalignant lesions: determination and its clinical significance]
[Telomerase, cell immortality and cancer]
Gastritis, Atrophic
Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases.
[Coordinated expression of c-Myc and telomerase activity in Helicobacter pylori infected gastric diseases]
[The significance of telomerase activity in patients with gastric cancer]
Gastroenteritis
Allogeneic hematopoietic stem cell transplantation and norovirus gastroenteritis: a previously unrecognized cause of morbidity.
Gastroesophageal Reflux
GERD is associated with shortened telomeres in the squamous epithelium of the distal esophagus.
Gastrointestinal Diseases
Telomerase activity and human telomerase RNA component in gastrointestinal diseases.
Gastrointestinal Neoplasms
A novel peptide-nucleotide dual vaccine of human telomerase reverse transcriptase induces a potent cytotoxic T-cell response in vivo.
Advantages of assaying telomerase activity in ascites for diagnosis of digestive tract malignancies.
Clinical significance of telomerase activity in peritoneal disseminated cells: gastrointestinal cancers.
Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.
Early detection of peritoneal dissemination of gastrointestinal cancers by reverse-transcriptase polymerase chain reaction.
Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1? and VEGF receptors.
Molecular-pathological diagnosis of gastrointestinal tissues and its contribution to cancer histopathology.
Telomerase activation and incidence of HPV in human gastrointestinal tumors in North Indian population.
Telomerase activity in different clinical staging of colorectal adenocarcinoma.
Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer.
[Telomerase and gastrointestinal cancer]
Gastrointestinal Stromal Tumors
Depletion of telomerase RNA inhibits growth of gastrointestinal tumors transplanted in mice.
Expression of human telomerase reverse transcriptase in gastrointestinal stromal tumors occurs preferentially in malignant neoplasms.
Gastrointestinal stromal tumors - quantitative detection of the Ki-67, TPX2, TOP2A, and hTERT telomerase subunit mRNA levels to determine a proliferation activity and a potential for aggressive biological behavior.
Gastrointestinal stromal tumors of the vermiform appendix: clinicopathologic, immunohistochemical, and molecular study of 2 cases with literature review.
Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs).
ShRNA-mediated BMI-1 gene silencing inhibits gastrointestinal stromal tumor cell telomerase activity and enhances apoptosis.
Study of the expressions of p53 and bcl-2 genes, the telomerase activity and apoptosis in GIST patients.
Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.
Telomerase activity as prognostic factor in gastrointestinal stromal tumors of the stomach.
Telomerase activity in gastrointestinal stromal tumors.
GATA2 Deficiency
Telomere dysfunction and hematologic disorders.
Genetic Diseases, Inborn
A phylogenetically based secondary structure for the yeast telomerase RNA.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in hoyeraal-hreidarsson syndrome.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndrome.
Life and Death of Yeast Telomerase RNA.
Medical genetics and epigenetics of telomerase.
Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of TERT.
Regulation of human telomerase in homeostasis and disease.
Regulation of senescence by telomeres and telomerase.
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity.
Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
Telomerase as a Therapeutic Target in Cardiovascular Disease.
Telomerase Dysfunction in the Tumorigenesis of Genetic Disorders.
Telomere and telomerase biology.
Telomere and telomerase in stem cells.
Telomere and telomerase in stem cells: relevance in ageing and disease.
Telomeres and telomerase: three decades of progress.
Telomeres in aging and disease: lessons from zebrafish.
Telomeres, NAFLD and Chronic Liver Disease.
Telomeropathies: Etiology, diagnosis, treatment and follow-up. Ethical and legal considerations.
The implications of telomerase biochemistry for human disease.
Gestational Trophoblastic Disease
Estrogen and progesterone receptors and telomerase enzyme immunohistochemical detection in gestational trophoblastic tumors.
Prevalence of telomerase activity in human cancer.
Telomerase activity in complete hydatidiform mole.
Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies.
Telomerase activity in gestational trophoblastic disease.
Giant Cell Tumor of Bone
Cytogenetic, telomere, and telomerase studies in five surgically managed lumbosacral chordomas.
Telomerase activity and oncogenesis in giant cell tumor of bone.
Giant Cell Tumors
Cytogenetic, telomere, and telomerase studies in five surgically managed lumbosacral chordomas.
Telomerase activity and oncogenesis in giant cell tumor of bone.
Telomerase activity in benign bone tumors and tumor-like lesions.
Telomerase activity in giant cell tumors of bone.
Glaucoma
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains.
Architecture of telomerase RNA.
Glioblastoma
1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents.
A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).
Activation of telomerase by human cytomegalovirus.
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.
Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461.
Anticancer Potential and Mechanism of Action of Mango Ginger (Curcuma amada Roxb.) Supercritical CO2 Extract in Human Glioblastoma Cells.
Antisense epidermal growth factor receptor RNA transfection in human glioblastoma cells down-regulates telomerase activity and telomere length.
Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction.
Assessment Effects of Resveratrol on Human Telomerase Reverse Transcriptase Messenger Ribonucleic Acid Transcript in Human Glioblastoma.
Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
Beyond the World Health Organization classification of central nervous system tumors 2016: what are the new developments for gliomas from a clinician's perspective?
Beyond the World Health Organization grading of infiltrating gliomas: advances in the molecular genetics of glioma classification.
Brain regions associated with telomerase reverse transcriptase promoter mutations in primary glioblastomas.
Butylidenephthalide Suppresses Human Telomerase Reverse Transcriptase (TERT) in Human Glioblastomas.
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
Clinicopathological Analysis of HIF-1alpha and TERT on Survival Outcome in Glioblastoma Patients: A Prospective, Single Institution Study.
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.
Detection of TERT Promoter Mutations Using Targeted Next-Generation Sequencing: Overcoming GC Bias through Trial and Error.
Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy.
Different assessments of immunohistochemically stained Ki-67 and hTERT in glioblastoma multiforme yield variable results: a study with reference to survival prognosis.
Differential telomerase expression in human primary intracranial tumors.
Differentiation Decreased Telomerase Activity in Rat Glioblastoma C6 Cells and Increased Sensitivity to IFN-gamma and Taxol for Apoptosis.
Diosgenin as a Novel Alternative Therapy for Inhibition of Growth, Invasion, and Angiogenesis Abilities of Different Glioblastoma Cell Lines.
Down regulation of human telomerase reverse transcriptase (hTERT) expression by BIBR1532 in human glioblastoma LN18 cells.
Droplet digital PCR assay for detecting TERT promoter mutations in patients with glioma.
EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers.
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase.
Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts.
Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
Frequency of TERT promoter mutations in human cancers.
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Glioblastoma in a female neurofibromatosis 1 patient without IDH1, BRAF V600E, and TERT promoter mutations: A case report.
Glioblastoma in neurofibromatosis 1 patients without IDH1, BRAF V600E, and TERT promoter mutations.
Glioblastoma induces vascular endothelial cells to express telomerase in vitro.
Highly sensitive detection of TERT promoter mutations in recurrent glioblastomas using digital PCR.
Human TERT promoter mutation enables survival advantage from MGMT promoter methylation in IDH1 wild-type primary glioblastoma treated by standard chemoradiotherapy.
In situ detection of telomerase catalytic subunit mRNA in glioblastoma multiforme.
In situ detection of telomeres by fluorescence in situ hybridization and telomerase activity in glioblastoma multiforme: correlation with p53 status, EGFR, c-myc, MIB1, and Topoisomerase IIalpha protein expression.
Increased expression of telomerase RNA component is associated with increased cell proliferation in human astrocytomas.
Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice.
Inhibition of melanoma growth by subcutaneous administration of hTERTC27 viral cocktail in C57BL/6 mice.
Inhibition of MUC1 exerts cell-cycle arrest and telomerase suppression in glioblastoma cells.
Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts.
Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis.
Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell lines.
Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner.
Meningiomas, dicentric chromosomes, gliomas, and telomerase activity.
Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes.
Molecular diagnostics of gliomas using next generation sequencing of a glioma-tailored gene panel.
Molecular mechanisms of the combination of retinoid and interferon-gamma for inducing differentiation and increasing apoptosis in human glioblastoma T98G and U87MG cells.
Molecular Testing of Brain Tumor.
MRI Features Associated with TERT Promoter Mutation Status in Glioblastoma.
MRI Features May Predict Molecular Features of Glioblastoma in Isocitrate Dehydrogenase Wild-Type Lower-Grade Gliomas.
N-(4-Hydroxyphenyl)retinamide induced differentiation with repression of telomerase and cell cycle to increase interferon-gamma sensitivity for apoptosis in human glioblastoma cells.
New prognostic factor telomerase reverse transcriptase promotor mutation presents without MR imaging biomarkers in primary glioblastoma.
New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma.
Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Predicting TERT promoter mutation using MR images in patients with wild-type IDH1 glioblastoma.
Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas.
Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.
Progression of astrocytomas and meningiomas: an evaluation in vitro.
Quantitative telomerase expression in glioblastomas shows regional variation and down-regulation with therapy but no correlation with patient outcome.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells.
RNA interference mediated downregulation of human telomerase reverse transcriptase (hTERT) in LN18 cells.
Silencing of telomere-binding protein adrenocortical dysplasia (ACD) homolog enhances radiosensitivity in glioblastoma cells.
Suppressing tumor growth of nasopharyngeal carcinoma by hTERTC27 polypeptide delivered through adeno-associated virus plus adenovirus vector cocktail.
Survival of diffuse astrocytic glioma, IDH1/2-wildtype, with molecular features of glioblastoma, WHO grade IV: a confirmation of the cIMPACT-NOW criteria.
Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation.
Survivin in glioblastomas. Protein and messenger RNA expression and comparison with telomerase levels.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and expression of telomerase reverse transcriptase correlated with cell proliferation in meningiomas and malignant brain tumors in vivo.
Telomerase activity and hTERT mRNA expression in glial tumors.
Telomerase activity in human brain tumours.
Telomerase activity in human gliomas.
Telomerase activity in primary and secondary glioblastomas multiforme as a novel molecular tumor marker.
Telomerase as a therapeutic target in glioblastoma.
Telomerase expression in intracranial tumours: prognostic potential for malignant gliomas and meningiomas.
Telomerase expression shows differences across multiple regions of oligodendroglioma versus high grade astrocytomas but shows correlation with Mib-1 labelling.
Telomerase inhibition by stable RNA interference impairs tumor growth and angiogenesis in glioblastoma xenografts.
Telomerase inhibition impairs tumor growth in glioblastoma xenografts.
Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.
Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma.
Telomerase reverse transcriptase promoter mutation- and O6-methylguanine DNA methyltransferase promoter methylation-mediated sensitivity to temozolomide in isocitrate dehydrogenase-wild-type glioblastoma: is there a link?
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Telomere biology of pediatric cancer.
Telomere profiles and tumor-associated macrophages with different immune signatures affect prognosis in glioblastoma.
Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells.
TERT Promoter Alterations in Glioblastoma: A Systematic Review.
TERT promoter mutation associated with multifocal phenotype and poor prognosis in patients with IDH wild-type glioblastoma.
TERT Promoter Mutation in Adult Glioblastomas: It's Correlation with Other Relevant Molecular Markers.
TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma.
The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas.
The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.
The significant role of telomerase activity in human brain tumors.
The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.
Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells.
[Azidothymidine inhibition of telomerase activity and proliferation of TJ905 human glioblastoma cells]
[Effect of antisense epidermal growth factor receptor cDNA transfection on telomerase activity of glioblastomas cells]
Glioma
18F-FET PET Uptake Characteristics of Long-Term IDH-Wildtype Diffuse Glioma Survivors.
2-5A antisense telomerase RNA therapy for intracranial malignant gliomas.
A genetically tractable model of human glioma formation.
A novel antisense oligonucleotide anchored on the intronic splicing enhancer of hTERT pre-mRNA inhibits telomerase activity and induces apoptosis in glioma cells.
A novel treatment of human malignant gliomas in vitro and in vivo: FADD gene transfer under the control of the human telomerase reverse transcriptase gene promoter.
A retrospective analysis of the risk factors affecting recurrence time in patients with recurrent glioblastoma.
Activation of telomerase by human cytomegalovirus.
Activation of telomerase in glioma cells by human cytomegalovirus: another piece of the puzzle.
Adenovirus-mediated over-expression of p21Waf-1 differentially affects the proliferation, telomerase activity, and expression of glial fibrillary acidic protein in human glioma cells.
Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.
Aggressive Treatment in Glioblastoma: What Determines the Survival of Patients?
Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461.
Anti-telomerase therapy suppressed glioma proliferation.
Antiglioma activity of curcumin-loaded lipid nanoparticles and its enhanced bioavailability in brain tissue for effective glioblastoma therapy.
Antisense epidermal growth factor receptor RNA transfection in human glioblastoma cells down-regulates telomerase activity and telomere length.
Antisense telomerase RNA inhibits the growth of human glioma cells in vitro and in vivo.
Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation.
Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction.
Association between telomerase reverse transcriptase rs2736100 polymorphism and risk of glioma.
Association of strong risk of hTERT gene polymorphic variants to malignant glioma and its prognostic implications with respect to different histological types and survival of glioma cases.
Association of telomerase gene hTERT polymorphism and malignant gliomas.
Association of Telomerase Reverse Transcriptase Promoter Mutations with the Prognosis of Glioma Patients: a Meta-Analysis.
Associations between microRNA expression and mesenchymal marker gene expression in glioblastoma.
Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus.
Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells.
Brain regions associated with telomerase reverse transcriptase promoter mutations in primary glioblastomas.
Caspase-8 gene therapy using the human telomerase reverse transcriptase promoter for malignant glioma cells.
Characteristics of the isocitrate dehydrogenase gene and telomerase reverse transcriptase promoter mutations in gliomas in Chinese patients.
Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas.
Clinical implications of TERT promoter mutation on IDH mutation and MGMT promoter methylation in diffuse gliomas.
Clinical significance of ABCA2' a possible molecular marker for oligodendrogliomas.
Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.
Combination of tamoxifen and antisense human telomerase RNA inhibits glioma cell proliferation and anti-apoptosis via suppression of telomerase activity.
Combination therapy of 2-5A antisense against telomerase RNA and cisplatin for malignant gliomas.
Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53.
Combined effect of 2-5A-linked antisense against telomerase RNA and conventional therapies on human malignant glioma cells in vitro and in vivo.
Contralesional Structural Plasticity in Different Molecular Pathologic Subtypes of Insular Glioma.
Conventional magnetic resonance imaging-based radiomic signature predicts telomerase reverse transcriptase promoter mutation status in grade II and III gliomas.
Correlation between genetic alterations and growth of human malignant glioma xenografted in nude mice.
Correlation between IDH, ATRX, and TERT promoter mutations in glioma.
Correlation of clinical features and telomerase activity in human gliomas.
Cotransfected sodium iodide symporter and human tyroperoxidase genes following human telomerase reverse transcriptase promoter for targeted radioiodine therapy of malignant glioma cells.
Detection of IDH1 and TERT promoter mutations with droplet digital PCR in diffuse gliomas.
Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis.
Differential hTERT mRNA processing between young and older glioma patients.
Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma, and glioma cells in culture.
Differential telomerase expression in human primary intracranial tumors.
Diffusion and perfusion MRI may predict EGFR amplification and the TERT promoter mutation status of IDH-wildtype lower-grade gliomas.
Direct vaccination with pseudotype baculovirus expressing murine telomerase induces anti-tumor immunity comparable with RNA-electroporated dendritic cells in a murine glioma model.
Down-regulation of telomerase activity in malignant glioma cells by p27KIP1.
E2F1 and telomerase: alliance in the dark side.
Elevated TERT Expression in TERT-Wildtype Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody.
Emerging interplay of genetics and epigenetics in gliomas: a new hope for targeted therapy.
Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.
Epitope mapping of an anti-alpha thalassemia/mental retardation syndrome X-linked monoclonal antibody AMab-6.
Establishment and Validation of the Detection of TERT Promoter Mutations by Human Gliomas U251 Cell Lines.
Evaluating the potential of circulating hTERT levels in glioma: can plasma levels serve as an independent prognostic marker?
Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts.
Evidence for telomerase involvement in the angiogenesis of astrocytic tumors: expression of human telomerase reverse transcriptase messenger RNA by vascular endothelial cells.
Expression in UVW glioma cells of the noradrenaline transporter gene, driven by the telomerase RNA promoter, induces active uptake of [131I]MIBG and clonogenic cell kill.
Expression of telomerase RNA, telomerase activity, and telomere length in human gliomas.
Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis.
Glial fibrillary acidic protein promoters direct adenovirus early 1A gene and human telomerase reverse transcriptase promoters direct sodium iodide symporter expression for malignant glioma radioiodine therapy.
Glioblastoma induces vascular endothelial cells to express telomerase in vitro.
Glioma: What is the role of c-Myc, hsp90 and telomerase?
Growth inhibition of human glioma cells by transfection-induced P21 and its effects on telomerase activity.
HDAC inhibitor Scriptaid induces glioma cell apoptosis through JNK activation and inhibits telomerase activity.
HHLA2 is a novel prognostic predictor and potential therapeutic target in malignant glioma.
High S phase kinase-associated protein 2 expression is a potential prognostic biomarker for glioma.
Histone deacetylase inhibitor AR42 regulates telomerase activity in human glioma cells via an Akt-dependent mechanism.
hTERT cancer risk genotypes are associated with telomere length.
Identification and functional characterization of glioma-specific promoters and their application in suicide gene therapy.
Identification of IDH and TERTp mutation status using 1 H-MRS in 112 hemispheric diffuse gliomas.
Identification of microRNAs in the cerebrospinal fluid as biomarker for the diagnosis of glioma.
Identifying Predictive Gene Expression and Signature Related to Temozolomide Sensitivity of Glioblastomas.
Implications of prognostic markers in brain tumors.
In situ detection of telomerase catalytic subunit mRNA in glioblastoma multiforme.
Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival.
Increased paired box transcription factor 8 has a survival function in Glioma.
Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.
Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide.
Introduction of p16INK4a inhibits telomerase activity through transcriptional suppression of human telomerase reverse transcriptase expression in human gliomas.
Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner.
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.
Management of diffusely infiltrating glioma in the elderly.
Manumycin inhibits STAT3, telomerase activity and growth of glioma cells by elevating intracellular reactive oxygen species generation.
Meningiomas, dicentric chromosomes, gliomas, and telomerase activity.
miR-15b and miR-21 as Circulating Biomarkers for Diagnosis of Glioma.
Molecular classification of gliomas.
Molecular diagnostics of gliomas using next generation sequencing of a glioma-tailored gene panel.
MRI Features May Predict Molecular Features of Glioblastoma in Isocitrate Dehydrogenase Wild-Type Lower-Grade Gliomas.
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas.
New Molecular Considerations for Glioma: IDH, ATRX, BRAF, TERT, H3 K27M.
Noninvasive Prediction of TERT Promoter Mutations in High-Grade Glioma by Radiomics Analysis Based on Multiparameter MRI.
Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma.
On the significance of telomerase activity in human malignant glioma cells.
Paradoxical prognostic impact of TERT promoter mutations in gliomas depends on different histological and genetic backgrounds.
PAX8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma.
PinX1 inhibits cell proliferation, migration and invasion in glioma cells.
Plasma miR-185 as a predictive biomarker for prognosis of malignant glioma.
Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival.
Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas.
Prognostic implication of telomerase activity in patients with brain tumors.
Proteomic studies coupled with RNAi methodologies can shed further light on the downstream effects of telomerase in glioma.
Quantitative telomerase expression in glioblastomas shows regional variation and down-regulation with therapy but no correlation with patient outcome.
Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines.
Radiomics Features Predict Telomerase Reverse Transcriptase Promoter Mutations in World Health Organization Grade II Gliomas via a Machine-Learning Approach.
Radiosensitization effect of zidovudine on human malignant glioma cells.
Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy.
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
Restoration of wild-type PTEN expression leads to apoptosis, induces differentiation, and reduces telomerase activity in human glioma cells.
Retraction Note to: The Clinical Implications of Human Telomerase Reverse Transcriptase Expression in Grade and Prognosis of Gliomas: a Systematic Review and Meta-analysis.
Role of GLTSCR2 in the regulation of telomerase activity and chromosome stability.
Role of traditional CHO PET parameters in distinguishing IDH, TERT and MGMT alterations in primary diffuse gliomas.
Rosette-Forming Glioneuronal Tumor Originating From the Spinal Cord: Report of 2 Cases and Literature Review.
Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.
Significance of TERT and ATRX mutations in glioma.
Silencing of the hTERT gene through RNA interference induces apoptosis via bax/bcl-2 in human glioma cells.
Specific gene suppression using antisense strategy for growth suppression of glioma.
Survival of diffuse astrocytic glioma, IDH1/2-wildtype, with molecular features of glioblastoma, WHO grade IV: a confirmation of the cIMPACT-NOW criteria.
Survivin in glioblastomas. Protein and messenger RNA expression and comparison with telomerase levels.
Synthetic 2'-O-methyl-modified hammerhead ribozymes targeted to the RNA component of telomerase as sequence-specific inhibitors of telomerase activity.
Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA.
Targeting Telomerase and ATRX/DAXX Inducing Tumor Senescence and Apoptosis in the Malignant Glioma.
Telomerase activity and hTERT mRNA expression in glial tumors.
Telomerase activity in 144 brain tumours.
Telomerase activity in gliomas with the use of non-radioisotopic and semi-quantitative procedure for terminal repeat amplification protocol.
Telomerase activity in human brain tumours.
Telomerase activity in human gliomas.
Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis.
Telomerase activity in microdissected human gliomas.
Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression.
Telomerase and DNA repair in glioma.
Telomerase as a therapeutic target for malignant gliomas.
Telomerase downregulation in cancer brain stem cell.
Telomerase expression in gliomas including the nonastrocytic tumors.
Telomerase expression in intracranial tumours: prognostic potential for malignant gliomas and meningiomas.
Telomerase inhibitors for the treatment of brain tumors and the potential of intranasal delivery.
Telomerase promoter mutations in cancer: an emerging molecular biomarker?
Telomerase reactivation in malignant gliomas and loss of heterozygosity on 10p15.1.
Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma.
Telomerase reverse transcriptase (TERT) rs2736100 polymorphism contributes to increased risk of glioma: evidence from a meta-analysis.
Telomerase reverse transcriptase promoter-driven expression of iodine pump genes for targeted radioiodine therapy of malignant glioma cells.
Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate.
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood.
Telomere length and telomerase catalytic subunit expression in non-astrocytic gliomas.
TERT and DNMT1 expression predict sensitivity to decitabine in gliomas.
TERT mutation in glioma: Frequency, prognosis and risk.
TERT Mutation Is Accompanied by Neutrophil Infiltration and Contributes to Poor Survival in Isocitrate Dehydrogenase Wild-Type Glioma.
TERT Promoter Mutation Analysis to Distinguish Glioma From Gliosis.
TERT promoter mutation and its interaction with IDH mutations in glioma: Combined TERT promoter and IDH mutations stratifies lower-grade glioma into distinct survival subgroups-A meta-analysis of aggregate data.
TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors.
TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas.
TERT promoter mutations contribute to IDH mutations in predicting differential responses to adjuvant therapies in WHO grade II and III diffuse gliomas.
TERT promoter mutations contribute to subset prognostication of lower-grade gliomas.
TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations.
TERT promoter mutations in telomere biology.
TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.
The Clinical Implications of Human Telomerase Reverse Transcriptase Expression in Grade and Prognosis of Gliomas: a Systematic Review and Meta-analysis.
The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells.
The inhibitory effects of ginsenoside Rd on the human glioma U251 cells and its underlying mechanisms.
The level of activity of the alternative lengthening of telomeres correlates with patient age in IDH-mutant ATRX-loss-of-expression anaplastic astrocytomas.
The opposing effect of hypoxia-inducible factor-2alpha on expression of telomerase reverse transcriptase.
The Sensitive Detection of Telomerase Reverse Transcriptase Promoter Mutation by Amplification Refractory Mutation System-PCR.
The sensitization of glioma cells to cisplatin and tamoxifen by the use of catechin.
Therapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.
Treatment of anaplastic glioma.
Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter.
Tumor-specific activity of cellular regulatory elements is down-regulated upon insertion into the herpes simplex virus genome.
Updates in prognostic markers for gliomas.
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss.
Upregulation of p-Smad2 contributes to FAT10-induced oncogenic activities in glioma.
Use of telomerase promoter mutations to mark specific molecular subsets with reciprocal clinical behavior in IDH mutant and IDH wild-type diffuse gliomas.
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
When the Ends Are Really the Beginnings: Targeting Telomerase for Treatment of GBM.
[Study on combined gene therapy for malignant gliomas transfected with antisense hTERT/PTEN in vitro and in vivo]
[Study on expression of ING1, human telomerase reverse transcriptase and telomerase-associated protein 1 genes in human gliomas]
Glomerulosclerosis, Focal Segmental
Conditionally immortalized human podocyte cell lines established from urine.
Glucagonoma
Telomerase activity in pancreatic endocrine tumors.
Glucose Intolerance
Antiretroviral use and other risks for HIV-associated neuropathies in an international cohort.
Clinical lipoatrophy in HIV-1 patients on HAART is not associated with increased abdominal girth, hyperlipidaemia or glucose intolerance.
Telomerase deficiency impairs glucose metabolism and insulin secretion.
Goiter
Expression of telomerase genes in thyroid carcinoma.
Goiter, Nodular
[Puncture hystobiopsy with tissue telomerase activity measurement in preoperative thyroid nodes diagnostics]
Gout
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity.
Graft vs Host Disease
Cytokine gene expression in peripheral blood mononuclear cells during graft-versus-host disease after allogeneic bone marrow transplantation.
Intracellular cytokine analysis of interferon-gamma in T cells of patients with chronic myeloid leukemia.
[Clinical application of gene technology to monitor bone marrow transplantation]
Granuloma
The cutaneous lesion in American leishmaniasis: leukocyte subsets, cellular interaction and cytokine production.
Granulosa Cell Tumor
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
[Immunohistochemical study on telomerase activity in ovarian sex-cord stromal tumors]
Graves Disease
Comparison of telomerase and CD44 expression as diagnostic tumor markers in lesions of the thyroid.
Detection and localization of chemokine gene expression in autoimmune thyroid disease.
Guillain-Barre Syndrome
Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies.
Lactic acidosis associated with severe neuromuscular weakness and stavudine therapy.
Gynecomastia
Drug-induced gynecomastia.
Efavirenz-induced gynecomastia in a prepubertal girl with human immunodeficiency virus infection: a case report.
Telomerase activity in human breast tumors.
Hamartoma
Overexpression of MLH-1 and psoriasin genes in cutaneous angiofibromas from tuberous sclerosis complex patients.
Head and Neck Neoplasms
Blockade of telomerase reverse transcriptase enhances chemosensitivity in head and neck cancers through inhibition of AKT/ERK signaling pathways.
Clinical implications of telomerase activity and inactivation of the tumor suppressor gene p16 (CDKN2A) in head and neck cancer.
Clinical usefulness of telomerase activation and telomere length in head and neck cancer.
Combined evaluation of expression of telomerase, survivin, and anti-apoptotic Bcl-2 family members in relation to loss of differentiation and apoptosis in human head and neck cancers.
Distinct profiles of TERT promoter mutations and telomerase expression in head and neck cancer and cervical carcinoma.
Evaluation of telomerase activation in head and neck cancer.
Expression Pattern of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase (hTERT) in Cancer Cell Lines Was not Associated with the Origin of the Cells.
Genomic instability in head and neck cancer patients.
hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells.
hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression.
Molecular characterization of head and neck tumors by analysis of telomerase activity and a panel of microsatellite markers.
Telomerase activity in head and neck cancer.
The prognostic value of telomerase expression in peripheral blood mononuclear cells of head and neck cancer patients.
Therapeutic effect of sodium iodide symporter gene therapy combined with external beam radiotherapy and targeted drugs that inhibit DNA repair.
[Inhibitory Effect of Silencing hTERT Gene by Short Hairpin RNA on Growth of Human Laryngeal Squamous Cell Carcinoma Xenograft in Nude Mice.]
[Prognostic and diagnostic value of telomerase in the head and neck cancer]
[Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck]
Hearing Loss
A C-terminal nonsense mutation links PTPRQ with autosomal-dominant hearing loss, DFNA73.
A prospective study of hearing changes after beginning zidovudine or didanosine in HIV-1 treatment-naive people.
Telomerase activity and cell proliferation index in cholesteatoma.
Heart Defects, Congenital
Cardiotropic viruses in the myocardium of children with end-stage heart disease.
Heart Diseases
Cardiotropic viruses in the myocardium of children with end-stage heart disease.
In situ Analysis of Cancer Cells Based on DNA Signal Amplification and DNA Nanodevices.
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
Reprogramming for Cardiac Regeneration-Strategies for Innovation.
Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury.
Telomerase therapeutics for degenerative diseases.
Telomeres and Telomerase in Heart Ontogenesis, Aging and Regeneration.
Telomeres as Therapeutic Targets in Heart Disease.
Heart Failure
Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.
Antioxidant therapy attenuates myocardial telomerase activity reduction in superoxide dismutase-deficient mice.
Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration.
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.
Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure.
Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.
Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury.
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart.
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.
Hemangioblastoma
Absence of tight junctions between microvascular endothelial cells in human cerebellar hemangioblastomas.
Human telomerase RNA expression and MIB-1 (Ki-67) proliferation index distinguish hemangioblastomas from metastatic renal cell carcinomas.
Hemangioma
Angiogenin: a potential serum marker of infantile hemangioma revealed by cDNA microarray analysis.
Hemangiopericytoma
Differential telomerase expression in human primary intracranial tumors.
hTERT promoter methylation in meningiomas and central nervous hemangiopericytomas.
Telomerase activity and alterations in telomere length in human brain tumors.
Hemangiosarcoma
[Breast hemangiosarcoma. Contribution of a case and review of the literature. Study of viral particles and RNA dependent DNA polymerase (inverse transcriptase) activity]
Hematologic Diseases
Increased telomerase activity is associated with shorter survival in patients with chronic phase chronic myeloid leukemia.
Targeting telomerase in hematologic malignancy.
Telomerase activity is prognostic in pediatric patients with acute myeloid leukemia: comparison with adult acute myeloid leukemia.
Telomerase and telomere biology in hematological diseases: A new therapeutic target.
Telomeres, telomerase, and hematopoietic stem cell biology.
[Analysis for telomerase activity in various hematologic disorders]
Hematologic Neoplasms
Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis.
Characterization of In Vitro G-Quadruplex Formation of Imetelstat Telomerase Inhibitor.
Clinical significance of telomerase genes (hTERC and hTERT) amplification in patients with acute myeloid leukemia.
Contributory role of microRNAs in anti-cancer effects of small molecule inhibitor of telomerase (BIBR1532) on acute promyelocytic leukemia cell line.
Crossroads of telomere biology and anticancer drug discovery.
Effective control of acute myeloid leukaemia and acute lymphoblastic leukaemia progression by telomerase specific adoptive T-cell therapy.
Effects of telomerase inhibitor on epigenetic chromatin modification enzymes in malignancies.
Paired multiplex reverse-transcriptase polymerase chain reaction (PMRT-PCR) analysis as a rapid and accurate diagnostic tool for the detection of MLL fusion genes in hematologic malignancies.
Targeting telomerase in hematologic malignancy.
Telomerase Activation in Hematological Malignancies.
Telomerase activity in normal leukocytes and in hematologic malignancies.
Telomerase in Acute Myeloid Leukemia: A Molecular Update on Diagnosis, Prognosis, and Treatment.
Telomerase in hematologic malignancies.
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.
Telomere Length and Hematological Disorders: A Review.
Telomeres and Telomerase in Hematopoietic Dysfunction: Prognostic Implications and Pharmacological Interventions.
Telomeres and telomerase in normal and malignant haematologic cells.
TERT promoter hotspot mutations in breast cancer.
The importance of the telomere and telomerase system in hematological malignancies.
The role of telomeres and telomerase in cancer research.
The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation.
The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignancies.
[Telomerase]
[Telomere length measurement of 10 Chinese patients with bone marrow failure syndrome.]
[Telomeres and telomerase activity: their role in aging and in neoplastic development]
Hematuria
Combined assay of CYFRA21-1, telomerase and vascular endothelial growth factor in the detection of bladder transitional cell carcinoma.
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Semi-quantitative analysis of telomerase activity of exfoliated cells in urine of patients with urothelial cancers: Causative factors affecting sensitivity and specificity.
Sensitivity and specificity of NMP-22, telomerase, and BTA in the detection of human bladder cancer.
Telomerase activity in diagnosis of bladder cancer.
Urinary telomerase and its possible role as a marker for bladder cancer.
[Molecular biological testing for diagnosis and treatment of urothelial cancer]
Hemorrhagic Fever with Renal Syndrome
Dobrava virus RNA load in patients who have hemorrhagic fever with renal syndrome.
Domestically acquired seoul virus causing hemorrhagic fever with renal syndrome-Maryland, 2008.
Utility of Nested Reverse-Transcriptase Polymerase Chain Reaction of Clinical Specimens for Early Diagnosis of Hemorrhagic Fever with Renal Syndrome.
Hemorrhagic Fever, Ebola
Clinical features of patients isolated for suspected Ebola virus disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study.
Hepatic Insufficiency
Alteration of cytochrome oxidase subunit I labeling is associated with severe mitochondriopathy in NRTI-related hepatotoxicity in HIV patients.
Hepatitis
Antiviral activity and intracellular metabolism of bis(tButylSATE) phosphotriester of beta-L-2',3'dideoxyadenosine, a potent inhibitor of HIV and HBV replication.
Emerging antiviral drugs.
Hepatic steatosis and HIV infection.
Hepatitis Associated Aplastic Anemia: A review.
Human telomerase reverse transcriptase messenger RNA (TERT mRNA) as a tumour marker for early detection of hepatocellular carcinoma.
Inhibition of human hepatitis B virus DNA polymerase and duck hepatitis B virus DNA polymerase by triphosphates of thymidine analogs and pharmacokinetic properties of the corresponding nucleosides.
Lactic acidosis in an HIV-infected patient receiving highly active antiretroviral therapy.
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis.
Safety of rilpivirine plus nucleoside reverse-transcriptase inhibitors in HIV-infected Taiwanese with a higher prevalence of hepatitis virus infection.
Subclones of drug-resistant hepatitis B virus mutants and the outcome of breakthrough hepatitis in patients treated with lamivudine.
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus status.
Telomerase expression and p53 status in hepatocellular carcinoma.
Telomerase repeat amplification protocol (TRAP) activity upon recombinant expression and purification of human telomerase in a bacterial system.
Tolerability of postexposure antiretroviral prophylaxis for occupational exposures to HIV.
TV-circRGPD6 Nanoparticle Suppresses Breast Cancer Stem Cell-Mediated Metastasis via the miR-26b/YAF2 Axis.
[Expressions of h-TERT, c-myc, PCNA and cell apoptosis in liver carcinogenesis]
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
Hepatitis B
A comprehensive HBV array for the detection of HBV mutants and genotype.
Adefovir dipivoxil loaded proliposomal powders with improved hepatoprotective activity: formulation, optimization, pharmacokinetic, and biodistribution studies.
Approved Antiviral Drugs over the Past 50 Years.
Assays for Hepatitis B Virus DNA-and RNA-Dependent DNA Polymerase Activities.
Azvudine, a novel nucleoside reverse transcriptase inhibitor showed good drug combination features and better inhibition on drug-resistant strains than lamivudine in vitro.
Binding site analysis of human HBV pol for molecular chaperonin, hsp60.
cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome.
Detection of an RNase H activity associated with hepadnaviruses.
Detection of DNA polymerase activities associated with purified duck hepatitis B virus core particles by using an activity gel assay.
Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis.
Effect of a combination of clevudine and emtricitabine with adenovirus-mediated delivery of gamma interferon in the woodchuck model of hepatitis B virus infection.
Effects of cell cycle on telomerase activity and on hepatitis B virus replication in HepG2 2.2.15 cells.
Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells.
Emergence of hepatitis B virus quasispecies with lower susceptibility to nucleos(t)ide analogues during lamivudine treatment.
Emergence of Lamivudine-Resistant HBV during Antiretroviral Therapy Including Lamivudine for Patients Coinfected with HIV and HBV in China.
Emerging antiviral drugs.
Emtricitabine/tenofovir disoproxil fumarate.
Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues.
Expression and purification of a functional human hepatitis B virus polymerase.
Expression of an enzymatically active polymerase of human hepatitis B virus in an coupled transcription-translation system.
Expression of RNase H of human hepatitis B virus polymerase in Escherichia coli.
Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites.
Extensive mutagenesis of the conserved box E motif in duck hepatitis B virus P protein reveals multiple functions in replication and a common structure with the primer grip in HIV-1 reverse transcriptase.
Factors influencing inadequate or suboptimal response to adefovir with or without genotypic resistance.
Hepatitis B Virus (HBV) Infection and Re-activation During Nucleos(t)ide Reverse Transcriptase Inhibitor-Sparing Antiretroviral Therapy in a High-HBV Endemicity Setting.
Hepatitis B virus containing the I233V mutation in the polymerase reverse-transcriptase domain remains sensitive to inhibition by adefovir.
Hepatitis B virus core protein enhances human telomerase reverse transcriptase expression and hepatocellular carcinoma cell proliferation in a c-Ets2-dependent manner.
Hepatitis B virus genetic diversity.
Hepatitis B virus protein preS2 potentially promotes HCC development via its transcriptional activation of hTERT.
Hepatitis B virus replication and mutation are autoregulated by interactions between surface antigen and HBeAg and the HBV DNA polymerase: a functional model with therapeutic implications.
Hepatitis B virus X gene induces human telomerase reverse transcriptase mRNA expression in cultured normal human cholangiocytes.
Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase.
Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.
High indinavir plasma concentrations in HIV-positive patients co-infected with hepatitis B or C virus treated with low doses of indinavir and ritonavir (400/100 mg twice a day) plus two nucleoside reverse transcriptase inhibitors.
High telomerase activity and long telomeres in advanced hepatocellular carcinomas with poor prognosis.
HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection.
Human hepatitis B virus polymerase interacts with the molecular chaperonin Hsp60.
Human immunodeficiency virus (HIV) Type 1 reverse transcriptase resistance mutations in hepatitis B virus (HBV)-HIV-coinfected patients treated for HBV chronic infection once daily with 10 milligrams of adefovir dipivoxil combined with lamivudine.
In vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase.
In vitro mitochondrial toxicity of metacavir, a new nucleoside reverse transcriptase inhibitor for treatment of hepatitis B virus.
In vitro phenotyping of recombinant hepatitis B virus containing the polymerase/reverse transcriptase gene from clinical isolates.
In vitro transfection of the hepatitis B virus PreS2 gene into the human hepatocarcinoma cell line HepG2 induces upregulation of human telomerase reverse transcriptase.
Inhibition of human hepatitis B virus DNA polymerase and duck hepatitis B virus DNA polymerase by triphosphates of thymidine analogs and pharmacokinetic properties of the corresponding nucleosides.
Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers.
Knockdown of NHP2 inhibits hepatitis B virus X protein-induced hepatocarcinogenesis via repressing TERT expression and disrupting the stability of telomerase complex.
Lamivudine resistance in untreated chronic hepatitis B patients in Turkey.
Large-scale production and structural and biophysical characterizations of the human hepatitis B virus polymerase.
Localization of HSP90 binding sites in the human hepatitis B virus polymerase.
Lopinavir/Ritonavir Pharmacokinetics, Efficacy, and Safety in HIV and Hepatitis B or C Coinfected Adults Without Symptoms of Hepatic Impairment.
Mechanism of antiviral activities of 3'-substituted L-nucleosides against 3TC-resistant HBV polymerase: a molecular modelling approach.
Molecular mimicry between a uveitopathogenic site of S-antigen and viral peptides. Induction of experimental autoimmune uveitis in Lewis rats.
Multiregional whole-genome sequencing of hepatocellular carcinoma with nodule-in-nodule appearance reveals stepwise cancer evolution.
Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.
No detectable resistance to tenofovir disoproxil fumarate after 6 years of therapy in patients with chronic hepatitis B.
Optimized expression from a synthetic gene of an untagged RNase H domain of human hepatitis B virus polymerase which is enzymatically active.
PD-L1 is induced on the hepatocyte surface via CKLF-like MARVEL transmembrane domain-containing protein 6 up-regulation by the anti-HBV drug Entecavir.
Preferred translation of human hepatitis B virus polymerase from core protein- but not from precore protein-specific transcript.
Prevalence of hepatitis B virus DNA polymerase mutations in treatment-naïve patients with chronic hepatitis B.
Quantification of 2'-deoxy-2'-?-fluoro-4'-azidocytidine in rat and dog plasma using liquid chromatography-quadrupole time-of-flight and liquid chromatography-triple quadrupole mass spectrometry: Application to bioavailability and pharmacokinetic studies.
Regulation of telomerase and telomeres: human tumor viruses take control.
Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development.
Reversibility of cirrhosis in HIV/HBV coinfection.
Ribonucleoprotein complex formation by the human hepatitis B virus polymerase.
RNase H activity of human hepatitis B virus polymerase expressed in Escherichia coli.
Selective inhibition of the reverse transcription of duck hepatitis B virus by binding of 2',3'-dideoxyguanosine 5'-triphosphate to the viral polymerase.
Severe skin rash with lamivudine in HIV infected patients: some unusual case reports.
Short-term lamivudine therapy in patients with chronic hepatitis B.
Stabilized oral nanostructured lipid carriers of Adefovir Dipivoxil as a potential liver targeting: Estimation of liver function panel and uptake following intravenous injection of radioiodinated indicator.
Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance.
Structure of the HIV-1 reverse transcriptase Q151M mutant: insights into the inhibitor resistance of HIV-1 reverse transcriptase and the structure of the nucleotide-binding pocket of Hepatitis B virus polymerase.
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus status.
Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma.
Tenofovir disoproxil fumarate.
The absence of up-regulation of telomerase activity during regeneration after partial hepatectomy in hepatitis B virus X gene transgenic mice.
The case of chronic hepatitis B treatment with tenofovir: an update for nephrologists.
The catalytic properties of human hepatitis B virus polymerase.
The rtL229 substitutions in the reverse transcriptase region of hepatitis B virus (HBV) polymerase are potentially associated with lamivudine resistance as a compensatory mutation.
Ultra-Deep Pyrosequencing of Hepatitis B Virus Quasispecies from Nucleoside and Nucleotide Reverse-Transcriptase Inhibitor (NRTI)-Treated Patients and NRTI-Naive Patients.
Upregulation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells.
Using PBPK Modeling to Predict Drug Exposure and Support Dosage Adjustments in Patients With Renal Impairment: An Example With Lamivudine.
Variable influence of mutational patterns in reverse-transcriptase domain on replication capacity of hepatitis B virus isolates from antiviral-experienced patients.
Variant of hepatitis B virus with primary resistance to adefovir.
Viral reverse transcriptases.
X protein of hepatitis B virus functions as a transcriptional corepressor on the human telomerase promoter.
YMDD mutants in patients with chronic hepatitis B before treatment are not selected by lamivudine.
[Clinical and molecular correlation between chronic hepatitis and hepatocellular carcinoma induced by hepatitis B virus]
[Clinical emergence features and implications of hepatitis B virus rtA181T mutation].
[Effect of cell cycle on telomerase activity of hepatoma cells and its relationship with replication of hepatitis B virus]
[Effects of hepatitis B virus X gene on apoptosis and the activity of telomerase in HepG(2) cells]
[The effect of hepatitis B virus X gene transfection on expression of human telomerase reverse transcriptase mRNA in human bile duct carcinoma cell lines]
Hepatitis B, Chronic
Association Between the Telomerase rs2736098_TT Genotype and a Lower Risk of Chronic Hepatitis B and Cirrhosis in Chinese Males.
Emergence of hepatitis B virus quasispecies with lower susceptibility to nucleos(t)ide analogues during lamivudine treatment.
Hepatitis B Virus preS/S Truncation Mutant rtM204I/sW196* Increases Carcinogenesis through Deregulated HIF1A, MGST2, and TGFbi.
Impact of Tenofovir Disoproxil-Induced Fanconi Syndrome on Bone Material Quality: A Case Report.
Inhibitory Effect of Nucleos(t)ide Analogs on Telomerase Activity and Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B.
Lamivudine resistance in untreated chronic hepatitis B patients in Turkey.
PD-L1 is induced on the hepatocyte surface via CKLF-like MARVEL transmembrane domain-containing protein 6 up-regulation by the anti-HBV drug Entecavir.
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis.
Significant SNPs Related to Telomere Length and Hepatocellular Carcinoma Risk in Chronic Hepatitis B Carriers
Similar risk of renal events among patients treated with tenofovir or entecavir for chronic hepatitis B.
Telomerase activity of peripheral blood lymphocytes in patients with chronic hepatitis B.
[Telomerase activity of peripheral blood mononuclear cells in patients with acquired immune dysfunction]
Hepatitis C
A homeopathic nosode, Hepatitis C 30 demonstrates anticancer effect against liver cancer cells in vitro by modulating telomerase and topoisomerase II activities as also by promoting apoptosis via intrinsic mitochondrial pathway.
A novel nested reverse-transcriptase polymerase chain reaction method for rapid hepatitis C virus detection and genotyping.
A tale of two strands: reverse-transcriptase polymerase chain reaction detection of hepatitis C virus replication.
Antiretroviral use and other risks for HIV-associated neuropathies in an international cohort.
Approved Antiviral Drugs over the Past 50 Years.
Assessment of Drug Interaction Potential Between the Hepatitis C Virus Direct-Acting Antiviral Agents Elbasvir/Grazoprevir and the Nucleotide Analog Reverse-Transcriptase Inhibitor Tenofovir Disoproxil Fumarate.
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection.
Azvudine, a novel nucleoside reverse transcriptase inhibitor showed good drug combination features and better inhibition on drug-resistant strains than lamivudine in vitro.
CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy.
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
Detection of genomic- and minus-strand of hepatitis C virus RNA in the liver of chronic hepatitis C patients by strand-specific semiquantitative reverse-transcriptase polymerase chain reaction.
Detection of hepatitis C virus RNA by reverse-transcriptase and polymerase chain reaction: clinical applications of quantitative analysis.
Determinants of Elevated Alkaline Phosphatase in Patients Infected with HIV.
Development of Anti-Viral Agents Using Molecular Modeling and Virtual Screening Techniques.
Development of anti-viral agents using molecular modeling and virtual screening techniques.
Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis.
Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein.
Early hepatitis C virus-RNA responses predict interferon treatment outcomes in chronic hepatitis C. The Consensus Interferon Study Group.
Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy.
HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes.
Hepatitis C virus core protein enhances Telomerase activity in Huh7 cells.
Hepatitis C virus core protein induces malignant transformation of biliary epithelial cells by activating nuclear factor-kappaB pathway.
Hepatitis C virus may infect extrahepatic tissues in patients with hepatitis C.
Hepatitis C virus nonstructural protein NS(3) and telomerase activity.
Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer.
In vitro combination studies of tenofovir and other nucleoside analogues with ribavirin against HIV-1.
Lymphoblastoid interferon alfa-n1 improves the long-term response to a 6-month course of treatment in chronic hepatitis C compared with recombinant interferon alfa-2b: results of an international randomized controlled trial. Clinical Advisory Group for the Hepatitis C Comparative Study.
NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase.
Only a small fraction of purified hepatitis C RNA-dependent RNA polymerase is catalytically competent: implications for viral replication and in vitro assays.
Pharmacokinetic evaluation of the effects of ribavirin on zidovudine triphosphate formation: ACTG 5092s Study Team.
Predictive factors of lopinavir/ritonavir discontinuation for drug-related toxicity: results from a cohort of 416 multi-experienced HIV-infected individuals.
Prevalence of hepatitis C and G virus infection in chronic hemodialysis patients.
Quantification of 2'-deoxy-2'-?-fluoro-4'-azidocytidine in rat and dog plasma using liquid chromatography-quadrupole time-of-flight and liquid chromatography-triple quadrupole mass spectrometry: Application to bioavailability and pharmacokinetic studies.
Regulation of telomerase and telomeres: human tumor viruses take control.
Risk factors for sexual and erectile dysfunction in HIV-infected men: the role of protease inhibitors.
Steatohepatitis in HIV-infected subjects: pathogenesis, clinical impact and implications in clinical management.
Study Design Characteristics and Pharmacological Mechanisms in International Clinical Trials Registry Platform: Registered Clinical Trials on Antiviral Drugs for COVID-19.
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus status.
Telomere length and telomerase reverse transcriptase mRNA expression in patients with hepatitis C.
TERC telomerase subunit gene copy number in different disease stages of non-hodgkin lymphoma and in hepatitis C.
The relationship between nevirapine plasma concentrations and abnormal liver function tests.
[Effect of hepatitis C virus nonstructural protein NS3 on telomerase activity]
Hepatitis C, Chronic
Detection of genomic- and minus-strand of hepatitis C virus RNA in the liver of chronic hepatitis C patients by strand-specific semiquantitative reverse-transcriptase polymerase chain reaction.
La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication.
Risk of liver decompensation with cumulative use of mitochondrial toxic nucleoside analogues in HIV/hepatitis C virus coinfection.
Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.
[CLINICAL AND PHARMACOECONOMIC RESULTS OF THE USAGE OF VARIOUS HIV REVERSE TRANSCRIPTASE INHIBITORS IN THE SCHEMES OF ANTIRETROVIRAL THERAPY OF PATIENT RECEIVING THERAPY FOR THE CHRONIC HEPATITIS C VIRUS].
Hepatitis E
Characterization of Seven Outbreaks of Hemorrhagic Hepatopathy Syndrome in Commercial Pullets Following the Administration of a Salmonella Enteritidis Bacterin in California.
Evidence for the presence of hepatitis E virus in pigs in the United Kingdom.
Hepatitis, Chronic
Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma.
Immuno-histochemical detection of human telomerase reverse transcriptase in human liver tissues.
Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis.
Quantitative analysis and in situ localization of human telomerase RNA in chronic liver disease and hepatocellular carcinoma.
Significance of telomerase activity in the diagnosis of small differentiated hepatocellular carcinoma.
Telomerase activity of needle-biopsied liver samples: its usefulness for diagnosis and judgement of efficacy of treatment of small hepatocellular carcinoma.
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus status.
Telomerase as a tool for the differential diagnosis of human hepatocellular carcinoma.
Telomerase is strongly activated in hepatocellular carcinoma but not in chronic hepatitis and cirrhosis.
Telomere shortening and telomerase reactivation in dysplastic nodules of human hepatocarcinogenesis.
The potential role of miRNAs 21 and 199-a in early diagnosis of hepatocellular carcinoma.
Hepatoblastoma
Effect of estradiol and bisphenol A on human hepatoblastoma cell viability and telomerase activity.
High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma.
Tamoxifen induces suppression of cell viability and apoptosis in the human hepatoblastoma cell line HepG2 via down-regulation of telomerase activity.
The tamoxifen-induced suppression of telomerase activity in the human hepatoblastoma cell line HepG2: a result of post-translational regulation.
Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability.
[Effects of antisense human telomerase reverse-transcript protein subunit (hTERT) gene on biological characteristics of hepatoblastoma cell line in vitro]
[IL-4 gene transfer induces the differentiation of cells and inhibits the activity of telomerase in hepatoblastoma cells]
Herpes Simplex
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model.
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase.
Active fulminant myocarditis characterized by T-lymphocytes expressing the gamma-delta T-cell receptor: a new disease entity?
Adenovirus Expressing Both Thymidine Kinase and Soluble PD1 Enhances Antitumor Immunity by Strengthening CD8 T-cell Response.
Combination of HSV1-TK/shTERT by retrovirus vector inhibits hepatocellular carcinoma cell growth in vitro and in vivo.
Development of genetically modified eliminable human dermal fibroblast feeder cells for ocular surface regeneration medicine.
Effect of acyclovir on HIV-1 set point among herpes simplex virus type 2-seropositive persons during early HIV-1 infection.
Emerging antiviral drugs.
Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells.
Human telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment.
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 "- (4"-amino-1",2"-oxathiole-2",2"-dioxide)thymine (TSAO-T).
Low p16(INK4a) Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone.
LY294002 Enhances Expression of Proteins Encoded by Recombinant Replication-Defective Adenoviruses via mTOR- and Non-mTOR-Dependent Mechanisms.
Mechanical allodynia induced by nucleoside reverse transcriptase inhibitor is suppressed by p55TNFSR mediated by herpes simplex virus vector through the SDF1?/CXCR4 system in rats.
New culture technique of human eliminable feeder-assisted target cell sheet production.
No selection of nucleoside reverse transcriptase inhibitor resistance associated mutations by acyclovir suppressive therapy in herpes simplex virus-2/HIV-1 dually infected persons.
Prevalence, type and concentration of human enterovirus and parechovirus in cerebrospinal fluid samples of pediatric patients over a 10-year period: a retrospective study.
Small Animal PET Imaging of hTERT RNA-Targeted HSV1-tk Gene Expression with Trans-Splicing Ribozyme.
The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants.
The Telomerase Inhibitor MST-312 Interferes with Multiple Steps in the Herpes Simplex Virus Life Cycle.
[A study on selective killing effect of Hsv-tk/GCV driven by human telomerase catalytic subunit promoter on human lung cancer cell A549]
Herpes Zoster
Elevated PD-1 expression and decreased telomerase activity in memory T cells of patients with symptomatic Herpes Zoster infection.
High incidence of herpes zoster in patients with AIDS soon after therapy with protease inhibitors.
Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish.
Herpesviridae Infections
Approved Antiviral Drugs over the Past 50 Years.
Histiocytoma, Malignant Fibrous
Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient with high telomerase activities.
Telomerase Activation in Malignant Bone Tumors.
Telomere-maintenance mechanisms in soft-tissue malignant fibrous histiocytomas.
Histiocytosis
Differences in telomerase expression by the CD1a+ cells in Langerhans cell histiocytosis reflect the diverse clinical presentation of the disease.
Histiocytosis, Langerhans-Cell
Differences in telomerase expression by the CD1a+ cells in Langerhans cell histiocytosis reflect the diverse clinical presentation of the disease.
histone acetyltransferase deficiency
The circadian rhythm controls telomeres and telomerase activity.
HIV Infections
2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants.
A brief overview of mechanisms of mitochondrial toxicity from NRTIs.
A cross-sectional study to evaluate the association of hyperbilirubinaemia on markers of cardiovascular disease, neurocognitive function, bone mineral density and renal markers in HIV-1 infected subjects on protease inhibitors.
A Matter of Life or Death: Productively Infected and Bystander CD4 T Cells in Early HIV Infection.
A review of the pharmacokinetics of abacavir.
Abacavir versus Zidovudine-based regimens for treatment of HIV-infected children in resource limited settings: a retrospective cohort study.
Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection.
Adverse cutaneous reactions associated with the newest antiretroviral drugs in patients with human immunodeficiency virus infection.
Alopecia areata associated with abacavir therapy.
Anti-tat hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages.
Antiretroviral treatment of HIV infection: Swedish recommendations 2005.
Antiviral efficacy and safety of abacavir-containing combination antiretroviral therapy as first-line treatment of HIV-infected children and adolescents: a systematic review protocol.
Approved Antiviral Drugs over the Past 50 Years.
Apricitabine--a novel nucleoside reverse transcriptase inhibitor for the treatment of HIV infection that is refractory to existing drugs.
Apricitabine: a novel deoxycytidine analogue nucleoside reverse transcriptase inhibitor for the treatment of nucleoside-resistant HIV infection.
Apricitabine: a nucleoside reverse transcriptase inhibitor for HIV infection.
Balancing antiviral potency and host toxicity: identifying a nucleotide inhibitor with an optimal kinetic phenotype for HIV-1 reverse transcriptase.
Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors.
Brain and CSF entry of the novel non-nucleoside reverse transcriptase inhibitor, GW420867X.
Challenges for the clinical development of new nucleoside reverse transcriptase inhibitors for HIV infection.
Circulating metabolites of the human immunodeficiency virus protease inhibitor nelfinavir in humans: structural identification, levels in plasma, and antiviral activities.
Co-infection of hepatic cell lines with HIV-hepatitis B virus (HBV) leads to an increase in intracellular hepatitis B surface antigen (HBsAg).
Comparison of the pharmacokinetics of apricitabine in the presence and absence of ritonavir-boosted tipranavir: a phase I, open-label, controlled, single-centre study.
Comprehensive analysis of the intracellular metabolism of antiretroviral nucleosides and nucleotides using liquid chromatography-tandem mass spectrometry and method improvement by using ultra performance liquid chromatography.
Cost-Effectiveness of Nucleoside Reverse Transcriptase Inhibitor Pairs in Efavirenz-Based Regimens for Treatment-Naïve Adults with HIV Infection in the United States.
Current treatment strategies, complications and considerations for the use of HIV antiretroviral therapy during pregnancy.
CYP2B6 genotype-directed dosing is required for optimal efavirenz exposure in children 3-36 months with HIV infection.
Decrease of vitamin D concentration in patients with HIV infection on a non nucleoside reverse transcriptase inhibitor-containing regimen.
Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography.
Development and optimization of anti-HIV nucleoside analogs and prodrugs: A review of their cellular pharmacology, structure-activity relationships and pharmacokinetics.
Development and Validation of an Up-to-Date Highly Sensitive UHPLC-MS/MS Method for the Simultaneous Quantification of Current Anti-HIV Nucleoside Analogues in Human Plasma.
Different origin of adipogenic stem cells influences the response to antiretroviral drugs.
Dolutegravir Plus Two Nucleoside Reverse Transcriptase Inhibitors versus Efavirenz Plus Two Nucleoside Reverse Transcriptase Inhibitors As Initial Antiretroviral Therapy for People with HIV: A Systematic Review.
Dual nucleoside regimens in nonadvanced HIV infection: prospective follow-up of 130 patients, Aquitaine Cohort, 1996 to 1998. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine (GECSA).
Dysregulation of autophagy in rat liver with mitochondrial DNA depletion induced by the nucleoside analogue zidovudine.
Early markers of tubular dysfunction in antiretroviral-experienced HIV-infected patients treated with tenofovir versus abacavir.
Early safety of tenofovir alafenamide in patients with a history of tubulopathy on tenofovir disoproxil fumarate: a randomized controlled clinical trial.
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals.
Efavirenz: a pharmacoeconomic review of its use in HIV infection.
Efficacy and safety of abacavir-containing combination antiretroviral therapy as first-line treatment of HIV infected children and adolescents: a systematic review and meta-analysis.
Elevated lactate levels in hospitalized persons with HIV infection.
Emerging antiviral drugs.
Emtricitabine: a review of its use in the management of HIV infection.
Emtricitabine: new preparation. An antiretroviral very similar to lamivudine.
Etravirine, a next-generation nonnucleoside reverse-transcriptase inhibitor.
Evaluation of antiretroviral effect on mitochondrial DNA depletion among HIV-infected patients in Bali.
Exploring CYP2B6 activity by measuring the presence ofnevirapine hydroxy metabolites in plasma.
Expression and functional activity of nucleoside transporters in human choroid plexus.
FDA notifications. NRTI Emtriva receives FDA approval.
Fixed Dose Combinations of Nucleoside Reverse Transcriptase Inhibitor for Naïve Patient with Hiv Infection in Russia: Cost Comparison Analysis.
Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy.
Higher Frequency of HIV-1 Drug Resistance and Increased Nucleoside Reverse Transcriptase Inhibitor Mutations among the HIV-1 Positive Antiretroviral Therapy-Naïve patients Coinfected With Mycobacterium tuberculosis Compared With Only HIV Infection in India.
HIV reverse transcriptase inhibiting antibodies detected by a new technique: relation to p24 and gp41 antibodies, HIV antigenemia and clinical variables.
HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: SAR and lead optimization using CoMFA and CoMSIA studies (1995-2016).
Identification and characterization of efavirenz metabolites by liquid chromatography/mass spectrometry and high field NMR: species differences in the metabolism of efavirenz.
Impact of Antiretroviral Treatment Containing Tenofovir Difumarate on the Telomere Length of Aviremic HIV-Infected Patients.
In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival.
In vitro interaction of nucleoside reverse transcriptase inhibitor, didanosine with calf-thymus DNA: Insights from spectroscopic studies.
Influence of Phosphatidylinositol-3-Kinase/Protein Kinase B-Mammalian Target of Rapamycin Signaling Pathway on the Neuropathic Pain Complicated by Nucleoside Reverse Transcriptase Inhibitors for the Treatment of HIV Infection.
Initial viral decay to assess the relative antiretroviral potency of protease inhibitor-sparing, nonnucleoside reverse transcriptase inhibitor-sparing, and nucleoside reverse transcriptase inhibitor-sparing regimens for first-line therapy of HIV infection.
Insights into the Molecular Mechanism of Polymerization and Nucleoside Reverse Transcriptase Inhibitor Incorporation by Human PrimPol.
Interferon and other biologic agents for the treatment of Kaposi's sarcoma.
Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro.
Intracellular phosphorylation of zidovudine (ZDV) and other nucleoside reverse transcriptase inhibitors (RTI) used for human immunodeficiency virus (HIV) infection.
Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.
Knocking out human immunodeficiency virus through non-nucleoside reverse transcriptase inhibitors used as single agents or in combinations: a paradigm for the cure of AIDS?
Lactic acidosis associated with severe neuromuscular weakness and stavudine therapy.
Lipid-lowering efficacy and safety after switching to atazanavir-ritonavir-based highly active antiretroviral therapy in patients with human immunodeficiency virus.
Liquid chromatography/mass spectrometry and high-field nuclear magnetic resonance characterization of novel mixed diconjugates of the non-nucleoside human immunodeficiency virus-1 reverse transcriptase inhibitor, efavirenz.
Liver damage underlying unexplained transaminase elevation in human immunodeficiency virus-1 mono-infected patients on antiretroviral therapy.
Longitudinal evaluation and risk factors of lipodystrophy and associated metabolic changes in HIV-infected children.
Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-ethynyl-2-fluoro-2'-deoxyadenosine triphosphate, a translocation defective reverse transcriptase inhibitor.
Metabolic health across the body mass index spectrum in HIV-Infected and HIV-Uninfected Men.
Mitochondrial changes during D-drug-containing once-daily therapy in HIV-positive treatment-naive patients.
Mitochondrial DNA levels in fat and blood cells from patients with lipodystrophy or peripheral neuropathy and the effect of 90 days of high-dose coenzyme Q treatment: a randomized, double-blind, placebo-controlled pilot study.
Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger.
Molecular dynamics and Monte Carlo simulations for protein-ligand binding and inhibitor design.
Myocarditis in CD8-depleted SIV-infected rhesus macaques after short-term dual therapy with nucleoside and nucleotide reverse transcriptase inhibitors.
Naringin Reverses Hepatocyte Apoptosis and Oxidative Stress Associated with HIV-1 Nucleotide Reverse Transcriptase Inhibitors-Induced Metabolic Complications.
Nelfinavir and non-nucleoside reverse transcriptase inhibitor-based salvage regimens in heavily HIV pretreated patients.
Nelfinavir: a review of its use in the management of HIV infection.
Nevirapine: a review of its use in the prevention and treatment of paediatric HIV infection.
New anti-HIV agents and targets.
New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.
Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials.
Novel peptides with HIV-1 reverse transcriptase inhibitory activity derived from the fruits of Quercus infectoria.
Nucleotide HIV reverse transcriptase inhibitors: tenofovir and beyond.
Occurrence of HIV-1 reverse transcriptase gene mutation at codon 215 in HIV-infected infants.
Overcoming resistance to existing therapies in HIV-infected patients: the role of new antiretroviral drugs.
Paediatric drug development: are population models predictive of pharmacokinetics across paediatric populations?
Peptide and non-peptide HIV fusion inhibitors.
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
Pharmacokinetic evaluation of emtricitabine in combination with other nucleoside antivirals in healthy volunteers.
Pharmacokinetics of Acetyl-L-Carnitine Given in Single or Multiple Doses to HIV-1 Infected Patients with Toxic Peripheral Polyneuropathy.
Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV.
Prevalence and factors associated with physical function limitation in older West African people living with HIV.
Prevalence of and Risk Factors for Prediabetes in Patients Infected With HIV.
Productively infected CD4+ cells express higher Human telomerase reverse transcriptase levels indicating a possible mechanism of persistence in HIV infection.
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
Renal excretion of apricitabine in rats: ex vivo and in vivo studies.
Resistance profile of the new nucleoside reverse transcriptase inhibitor apricitabine.
Ritonavir-Boosted Darunavir Plus Two Nucleoside Reverse Transcriptase Inhibitors versus Other Regimens for Initial Antiretroviral Therapy for People with HIV Infection: A Systematic Review.
Saquinavir soft-gel capsule: an updated review of its use in the management of HIV infection.
State-of-the-art tools unveil potent drug targets amongst clinically approved drugs to inhibit helicase in SARS-CoV-2.
Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors.
Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors.
Telomere length, telomerase activity, and replicative potential in HIV infection: analysis of CD4+ and CD8+ T cells from HIV-discordant monozygotic twins.
Tenofovir or zidovudine in three-drug combination therapy with one nucleoside reverse transcriptase inhibitor and one non-nucleoside reverse transcriptase inhibitor for initial treatment of HIV infection in antiretroviral-naïve individuals.
Tenofovir: a nucleotide analogue reverse-transcriptase inhibitor for treatment of HIV infection.
The abacavir hypersensitivity reaction: a review.
The choice of HIV protease inhibitor: indinavir is currently the best option.
The genetic toxicity effects of lamivudine and stavudine antiretroviral agents.
The history of antiretrovirals: key discoveries over the past 25 years.
The influence of natural substrates and inhibitors on the nucleotide-dependent excision activity of HIV-1 reverse transcriptase in the infected cell.
The nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors in the treatment of HIV infections (AIDS).
The picture of future therapy.
The protease inhibitors.
Towards an early diagnosis of HIV infection: an electrochemical approach for detection of HIV-1 reverse transcriptase enzyme.
Two-drug regimens for treatment of naïve HIV-1 infection and as maintenance therapy.
Viral reverse transcriptases.
Zidovudine induced pure red cell aplasia: a case report.
Zidovudine/lamivudine for HIV-1 infection contributes to limb fat loss.
[Antiretroviral therapy and immune reconstitution]
[Benign symmetrical lipomatosis ("peripheral lipodystrophy") during antiretroviral therapy of HIV infection]
[Drug clinics. How I treat HIV infections. II. Nucleoside reverse transcriptase inhibitors]
[Pharma-clinics. How I treat ... HIV infection. III. Non-nucleoside reverse transcriptase inhibitors]
HIV Seropositivity
Peripheral blood mononuclear cells of HIV- and HCV-antibody-positive individuals contain HCV RNA but No HCV DNA despite evidence for reverse transcription of HIV RNA into DNA.
HIV-Associated Lipodystrophy Syndrome
Cutaneous toxicities of antiretroviral therapy for HIV: part I. Lipodystrophy syndrome, nucleoside reverse transcriptase inhibitors, and protease inhibitors.
HIV-related lipodystrophy and facial lipoatrophy: The role of Restylane SubQ in reversing facial wasting.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Hodgkin Disease
CD30-ligand and CD40-ligand expression in lymph nodes involved with Hodgkin's disease.
Expression of bcl-2 protein and transcription of the Epstein-Barr virus bcl-2 homologue BHRF-1 in Hodgkin's disease: implications for different pathogenic mechanisms.
Hodgkin and Reed-Sternberg cells of classical Hodgkin's disease overexpress the telomerase RNA template (hTR).
Human recombination activating gene-1 in leukemia/lymphoma cells: expression depends on stage of lymphoid differentiation defined by phenotype and genotype.
Keeping those telomeres short! an innovative intratumoral long-term drug delivery system.
Possible immortalization of Hodgkin and Reed-Sternberg cells: telomerase expression, lengthening of telomere, and inhibition of apoptosis by NF-kappaB expression.
Quantitative measurement of telomerase activity in lymphadenopathy: correlation with histologic features and human immunodeficiency virus-1 infection.
Telomerase activity in Hodgkin's disease.
Telomerase activity in reactive and neoplastic lymphoid tissues: infrequent detection of activity in Hodgkin's disease.
The Transition between Telomerase and ALT Mechanisms in Hodgkin Lymphoma and Its Predictive Value in Clinical Outcomes.
HTLV-I Infections
Telomerase regulation in HTLV-I infection.
Hydatidiform Mole
Comparison of telomerase activity in normal chorionic villi to trophoblastic diseases.
Estrogen and progesterone receptors and telomerase enzyme immunohistochemical detection in gestational trophoblastic tumors.
Expression of human telomerase reverse transcriptase, the catalytic subunit of telomerase, is associated with the development of persistent disease in complete hydatidiform moles.
Expression of telomerase subunits and localization of telomerase activation in hydatidiform mole.
Localization of telomerase hTERT protein and survivin in placenta: relation to placental development and hydatidiform mole.
Telomerase activity and the subunit of telomerase in hydatidiform mole and their relationship with the development of postmolar tumor.
Telomerase activity in complete hydatidiform mole.
Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies.
Telomerase activity in gestational trophoblastic disease.
Hydatidiform Mole, Invasive
Telomerase activity in complete hydatidiform mole.
Hydronephrosis
[Prognostic factors of infiltrating bladder tumors]
Hyperaldosteronism
[Telomerase expression in various lesions of adrenal cortex]
Hyperalgesia
Hyperalgesia induced by oral stavudine administration to rats does not depend on spinal neuronal cell death, or on spinal or systemic inflammatory cytokine secretion, or metabolic dysregulation.
Mechanical allodynia induced by nucleoside reverse transcriptase inhibitor is suppressed by p55TNFSR mediated by herpes simplex virus vector through the SDF1?/CXCR4 system in rats.
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Induce Pathological Pain through Wnt5a-Mediated Neuroinflammation in Aging Mice.
Hypercalcemia
A novel ALL-L3 cell line, BALM-16, lacking expression of immunoglobulin chains derived from a patient with hypercalcemia.
Hypercholesterolemia
Evaluation and management of dyslipidemia in patients with HIV infection.
Improvement of dyslipidemia in patients switching from stavudine to tenofovir: preliminary results.
Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review.
Short telomeres protect from diet-induced atherosclerosis in apolipoprotein E-null mice.
[From cardiovascular prevention to anti-aging medicine: influence on telomere and cell aging].
Hyperglycemia
Differentiated PDGFR?-Positive Cells: A Novel In-Vitro Model for Functional Studies of Neuronal Nitric Oxide Synthase.
Evidence for Telomerase Activation in VSMCs Exposed to Hyperglycemic and Hyperhomocysteinemic Conditions.
High glucose-induced replicative senescence: point of no return and effect of telomerase.
The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro.
Hyperhomocysteinemia
Evidence for Telomerase Activation in VSMCs Exposed to Hyperglycemic and Hyperhomocysteinemic Conditions.
Hyperinsulinism
The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro.
Hyperlactatemia
A high incidence of lactic acidosis and symptomatic hyperlactatemia in women receiving highly active antiretroviral therapy in Soweto, South Africa.
Depleted skeletal muscle mitochondrial DNA, hyperlactatemia, and decreased oxidative capacity in HIV-infected patients on highly active antiretroviral therapy.
Effect of antioxidants on glucose metabolism and plasma lipids in HIV-infected subjects with lipoatrophy.
Hyperlactatemia and antiretroviral therapy: the Swiss HIV Cohort Study.
Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudine.
Lactate levels in children with HIV/AIDS on highly active antiretroviral therapy.
Mild to moderate symptoms do not correlate with lactate levels in HIV-positive patients on nucleoside reverse transcriptase inhibitors.
Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.
Symptomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a resource-limited setting (Uganda).
Symptomatic hyperlactatemia in a patient on nucleoside reverse transcriptase inhibitors.
The relationship between nucleoside analogue treatment duration, insulin resistance, and fasting arterialized lactate level in patients with HIV infection.
The role of nucleoside reverse transcriptase inhibitors usage in the incidence of hyperlactatemia and lactic acidosis in HIV/AIDS patients.
Unrecognized near-fatal hyperlactatemia in an HIV-infected infant exposed to nucleoside reverse transcriptase inhibitors.
[Treatment of symptomatic hyperlactatemia and lactic acidosis in HIV+ patients under nucleoside reverse transcriptase inhibitors]
Hyperlipidemias
Effect of antiretroviral therapy use and adherence on the risk of hyperlipidemia among HIV-infected patients, in the highly active antiretroviral therapy era.
Fat redistribution in indinavir-treated patients with HIV infection: A review of postmarketing cases.
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
[Side effects of antiretroviral therapy]
Hyperparathyroidism
Telomerase is not activated in human hyperplastic and adenomatous parathyroid tissue.
Hyperparathyroidism, Primary
Telomerase is not activated in human hyperplastic and adenomatous parathyroid tissue.
Hyperpigmentation
Engineered telomere degradation models dyskeratosis congenita.
Hypersensitivity
A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase.
A transgenic mouse model for HLA-B*57:01-linked abacavir drug tolerance and reactivity.
Absence of human leukocyte antigen-B*57:01 amongst patients on antiretroviral therapy in Nigeria: Implications for use of abacavir.
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir.
CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.
Dermatologic adverse effects of antiretroviral therapy: recognition and management.
High Frequency of Human Leukocyte Antigen-B*57:01 Allele Carriers among HIV-Infected Patients in Serbia.
Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir.
Long-term safety and efficacy of nevirapine tolerance induction.
Low-cost simultaneous detection of CCR5-delta32 and HLA-B*5701 alleles in human immunodeficiency virus type 1 infected patients by selective multiplex endpoint PCR.
Managing issues related to antiretroviral therapy.
Pharmacogenetics to predict drug-related adverse events.
Prevalence of HLA-B*5701 in HIV-Infected Patients in Spain (Results of the EPI Study).
Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.
Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors.
Severe myositis on commencement of efavirenz, abacavir and lamivudine, in the absence of lactic acidosis or classical abacavir hypersensitivity.
Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage.
The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy.
tRNA ADENOSINE DEAMINASE 3 is required for telomere maintenance in Arabidopsis thaliana.
Hypertension
Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?
Brief Report: Impact of ART Classes on the Increasing Risk of Cerebral Small-Vessel Disease in Middle-Aged, Well-Controlled, cART-Treated, HIV-Infected Individuals.
Coexistence of obstructive sleep apnea and telomerase activity, concentration of selected adipose tissue hormones and vascular endothelial function in patients with arterial hypertension.
DNA methylation of human telomerase reverse transcriptase associated with leukocyte telomere length shortening in hyperhomocysteinemia-type hypertension in humans and in a rat model.
Higher Prevalence of Hypertension in HIV-1-Infected Patients on Combination Antiretroviral Therapy Is Associated With Changes in Body Composition and Prior Stavudine Exposure.
Influence of Moxonidine and Bisoprolol on Morphofunctional Condition of Arterial Wall and Telomerase Activity in Postmenopausal Women with Arterial Hypertension and Osteopenia. The Results from a Moscow Randomized Study.
Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production.
Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Predictors of hypertension and changes of blood pressure in HIV-infected patients.
Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.
Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension.
Telomere dysfunction in hypertension.
Telomeres and essential hypertension.
[Telomerase activity in peripheral blood leukocytes from patients with essential hypertension]
Hypertension, Pulmonary
Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension.
Role for telomerase in pulmonary hypertension.
Hypertriglyceridemia
Acute pancreatitis in HIV/AIDS patients: an issue of concern.
Evaluation and management of dyslipidemia in patients with HIV infection.
Human immunodeficiency virus genotype and hypertriglyceridemia.
Improvement of dyslipidemia in patients switching from stavudine to tenofovir: preliminary results.
Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review.
[Pharmaceutical follow up of antirretroviral treatment in outpatients].
Hypertrophy, Left Ventricular
Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats.
Hypophosphatemia
Serum electrolytes and renal alterations in HIV-seropositive Mexican subjects.
Hypothyroidism
Quantification of MyoD, myogenin, MRF4 and Id-1 by reverse-transcriptase polymerase chain reaction in rat muscles--effects of hypothyroidism and chronic low-frequency stimulation.
[Thyroid dysfunction in adults infected by human immunodeficiency virus].
Idiopathic Interstitial Pneumonias
Telomere shortening in familial and sporadic pulmonary fibrosis.
Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.
Idiopathic Pulmonary Fibrosis
A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.
A Rare Missense Variant in Telomerase Reverse Transcriptase is Associated with Idiopathic Pulmonary Fibrosis in a Chinese Han Family.
A spectrum of severe familial liver disorders associate with telomerase mutations.
Abnormal expression of telomerase/apoptosis limits type II alveolar epithelial cell replication in the early remodeling of usual interstitial pneumonia/idiopathic pulmonary fibrosis.
Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study.
Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis.
Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer.
Differing Expression of Cytokines and Tumor Markers in Combined Pulmonary Fibrosis and Emphysema Compared to Emphysema and Pulmonary Fibrosis.
Exome sequencing identifies mutant TINF2 in a family with pulmonary fibrosis.
hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms.
Increased fibroblast telomerase expression precedes myofibroblast ?-smooth muscle actin expression in idiopathic pulmonary fibrosis.
Medical genetics and epigenetics of telomerase.
Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia.
Regulation of human telomerase in homeostasis and disease.
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies.
Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
Subclinical Lung Disease, Macrocytosis and Premature Graying in Kindreds with Telomerase (TERT) Mutations.
Syndromes of Telomere Shortening.
Telomerase and idiopathic pulmonary fibrosis.
Telomerase and Telomere Length in Pulmonary Fibrosis.
Telomerase and the Genetics of Emphysema Susceptibility. Implications for Pathogenesis Paradigms and Patient Care.
Telomerase gene mutations and telomere length shortening in patients with idiopathic pulmonary fibrosis in a Chinese population.
Telomerase mutations in families with idiopathic pulmonary fibrosis.
Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence.
Telomere elongation and naive pluripotent stem cells achieved from telomerase haplo-insufficient cells by somatic cell nuclear transfer.
Telomere Length is a Determinant of Emphysema Susceptibility.
Telomere length, stem cells and aging.
Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations.
Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease.
Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.
Telomeres in lung diseases.
The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications.
The role of telomeres and telomerase in cancer research.
Vascular dysfunction by myofibroblast activation in patients with idiopathic pulmonary fibrosis and prognostic significance.
Immune Reconstitution Inflammatory Syndrome
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Immune System Diseases
Activation of telomerase is induced by a natural antigen in allergen-specific memory T lymphocytes in bronchial asthma.
Incontinentia Pigmenti
Pigmentary disorders of the eyes and skin.
Infarction, Middle Cerebral Artery
Deficiency of telomerase activity aggravates the blood-brain barrier disruption and neuroinflammatory responses in a model of experimental stroke.
Telomerase induction in astrocytes of Sprague-Dawley rat after ischemic brain injury.
Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2/STAT3-involved apoptosis and inflammatory pathways.
Infections
3'-Azido-2',3'-dideoxythymidine (zidovudine) uptake mechanisms in T lymphocytes.
A case of lactic acidosis caused by stavudine in an AIDS patient.
A nanoparticle-encapsulated non-nucleoside reverse-transcriptase inhibitor with enhanced anti-HIV-1 activity and prolonged circulation time in plasma.
A Novel Approach to Helicobacter pylori Pan-Genome Analysis for Identification of Genomic Islands.
A novel human cancer culture model for the study of prostate cancer.
A novel human cell culture model for the study of familial prostate cancer.
A p6Pol-protease fusion protein is present in mature particles of human immunodeficiency virus type 1.
A peptide inhibitor of HIV-1 reverse transcriptase using alpha,beta-dehydro residues: a structure-based computer model.
A prospective, multicentre, cohort study to assess the incidence of dengue illness in households from selected communities in Brazil (2014-2018).
A role of Wnt/beta-catenin signals in hepatic fate specification of human umbilical cord blood-derived mesenchymal stem cells.
A transient kinetic approach to investigate nucleoside inhibitors of mitochondrial DNA polymerase gamma.
A Two-Way Steady-State Pharmacokinetic Interaction Study of Doravirine (MK-1439) and Dolutegravir.
Abacavir-lamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy.
Absence of c-kit receptor and absent proliferative response to stem cell factor in childhood Burkitt's lymphoma cells.
Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells.
Accumulation of mitochondrial DNA mutations in human immunodeficiency virus-infected patients treated with nucleoside-analogue reverse-transcriptase inhibitors.
Activation of telomerase by human cytomegalovirus.
Acute pancreatitis associated with different combination therapies in patients infected with human immunodeficiency virus.
Acute renal failure in an AIDS patient on tenofovir: a case report.
Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription.
Adult Measles - Case Reports of a Highly Contagious Disease.
Advances in the treatment of chronic hepatitis B virus infection.
Adverse effects of antiretroviral drugs on HIV-1-infected and -uninfected human monocyte-derived macrophages.
Amplification of the chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells.
An avian oncovirus mutant (SE 21Q1b) deficient in genomic RNA: biological and biochemical characterization.
An initiative to assess the quality of Tanzanian cervical cancer specimens for HPV and telomerase detection.
An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study.
Analysis of HIV type 1 reverse transcriptase expression in a human cell line.
Analysis of HIV-1 reverse transcriptase gene mutations in infected children treated with zidovudine.
Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase.
Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line.
Anti-CD3/28 mediated expansion of macaque CD4+ T cells is polyclonal and provides extended survival after adoptive transfer.
Anti-HIV-1 activity of herbs in Labiatae.
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus.
Antiretroviral drug-resistant HIV-2 infection--a new therapeutic dilemma.
Antiretroviral treatment in pediatric HIV infection in the United States: from clinical trials to clinical practice.
Antitumor effect of COOH-terminal polypeptide of human TERT is associated with the declined expression of hTERT and NF-?B p65 in HeLa cells.
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.
Antiviral and pharmacokinetic properties of C2 symmetric inhibitors of the human immunodeficiency virus type 1 protease.
Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): retroviruses and hepadnaviruses.
Antiviral drugs in current clinical use.
Approved Antiviral Drugs over the Past 50 Years.
Assessment of second-line antiretroviral regimens for HIV therapy in Africa.
Association of p16(INK4a) and pRb inactivation with immortalization of human cells.
Baicalin, an inhibitor of HIV-1 production in vitro.
Bovine herpesvirus type 1 (BHV-1) up-regulates telomerase activity in MDBK cells.
Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised, phase 2b, dose-ranging trial.
CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy.
Cell line-dependent release of HIV-like gag particles after infection of mammalian cells with recombinant vaccinia viruses.
Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study.
Cellulases belonging to glycoside hydrolase families 6 and 7 contribute to the virulence of Magnaporthe oryzae.
Chain-terminating dinucleoside tetraphosphates are substrates for DNA polymerization by human immunodeficiency virus type 1 reverse transcriptase with increased activity against thymidine analogue-resistant mutants.
Characterization of HeLa cells persistently infected with influenza virus B/Lee/40 with respect to telomerase activity and apoptosis.
Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells.
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase.
Chlamydia pneumoniae infection of endothelial cells induces transcriptional activation of platelet-derived growth factor-B: a potential link to intimal thickening in a rabbit model of atherosclerosis.
Chlamydia trachomatis inhibits telomeric DNA damage signaling via transient hTERT upregulation.
Class-sparing regimens for initial treatment of HIV-1 infection.
Clinical and Virologic Outcomes Following Initiation of Antiretroviral Therapy Among Seroconverters in the MTN-020/ASPIRE Phase III Trial of the Dapivirine Vaginal Ring.
Clinical features of initial cases of 2009 pandemic influenza A (H1N1) in Macau, China.
Clinical outcomes of lung transplant recipients with telomerase mutations.
Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of Korea.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection.
Combined analysis of two-year follow-up from two open-label randomized trials comparing efficacy of three nucleoside reverse transcriptase inhibitor backbones for previously untreated HIV-1 infection: OzCombo 1 and 2.
Comparison of HBV ribonuclease H domain in naïve and drug resistant patients.
Comprehensive in vitro analysis of simian retrovirus type 4 susceptibility to antiretroviral agents.
Conformational Plasticity of the NNRTI-Binding Pocket in HIV-1 Reverse Transcriptase: A Fluorine Nuclear Magnetic Resonance Study.
Container Type Influences the Relative Abundance, Body Size, and Susceptibility of Ochlerotatus triseriatus (Diptera: Culicidae) to La Crosse Virus.
Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases.
Coronavirus as a possible cause of severe acute respiratory syndrome.
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
Critically ill children with pandemic influenza (H1N1) in pediatric intensive care units in Turkey.
CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.
Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells.
Cytomegalovirus infection status predicts progression of heart-transplant vasculopathy.
Cytomegalovirus is associated with reduced telomerase activity in the Whitehall II cohort.
Dengue virus infects macrophages and dendritic cells in a mouse model of infection.
Dengue Virus Seroprevalence Among Febrile Patients in Bamako, Mali: Results of a 2006 Surveillance Study.
Design of reverse transcriptase-specific nucleosides to visualize early steps of HIV-1 replication by click labeling.
Design, synthesis, and biological evaluation of new 2'-deoxy-2'-fluoro-4'-triazole cytidine nucleosides as potent antiviral agents.
Detection of low-level K65R variants in nucleoside reverse transcriptase inhibitor-naive chronic and acute HIV-1 subtype C infections.
Determinants of Elevated Alkaline Phosphatase in Patients Infected with HIV.
Development of a reverse transcriptase loop-mediated isothermal amplification (LAMP) assay for the sensitive detection of Leishmania parasites in clinical samples.
Development of an in vivo assay to identify structural determinants in murine leukemia virus reverse transcriptase important for fidelity.
Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer.
Development of three additional Culex species-specific polymerase chain reaction primers and their application in West Nile virus surveillance in Canada.
Developmental Pharmacokinetic Changes of Lamivudine in Infants and Children.
Diagnosis of bladder cancer using telomerase activity in voided urine.
Diagnostic assays for active infection with human herpesvirus 6 (HHV-6).
Dicaffeoylquinic and dicaffeoyltartaric acids are selective inhibitors of human immunodeficiency virus type 1 integrase.
Differential Expression of Local Immune Response Genes in the Vagina: Implication for the Diagnosis of Vaginal Infections.
Distinct cytokine pattern in response to different bacterial pathogens in human brain abscess.
Distinct mechanisms for mitochondrial DNA loss in T and B lymphocytes from HIV-infected patients exposed to nucleoside reverse-transcriptase inhibitors and those naive to antiretroviral treatment.
Dolutegravir And Lamivudine Combination For The Treatment Of HIV-1 Infection.
Dolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV.
Dolutegravir versus ritonavir-boosted lopinavir both with dual nucleoside reverse transcriptase inhibitor therapy in adults with HIV-1 infection in whom first-line therapy has failed (DAWNING): an open-label, non-inferiority, phase 3b trial.
Dolutegravir/Lamivudine Single-Tablet Regimen: A Review in HIV-1 Infection.
Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial.
Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein.
Dual therapy with lopinavir and ritonavir plus lamivudine versus triple therapy with lopinavir and ritonavir plus two nucleoside reverse transcriptase inhibitors in antiretroviral-therapy-naive adults with HIV-1 infection: 48 week results of the randomised, open label, non-inferiority GARDEL trial.
Eastern equine encephalomyelitis virus infection in six captive southern cassowaries (Casuarius casuarius).
Effect of coadministration of neurovite and Lamivudine on the histomorphology of the cerebellum of wistar rats.
Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004-2005 season to the 2006-2007 season.
Effects of escin on indinavir crystallization time in the urine of patients with HIV-I infection: a multicenter, randomized, open-label, controlled, four-period crossover trial.
Effects of Nucleopolyhedrovirus Infection on the Development of Helicoverpa armigera (Lepidoptera: Noctuidae) and Expression of Its 20-Hydroxyecdysone—and Juvenile Hormone—Related Genes
Efficacy and safety of nucleoside reverse transcriptase inhibitor-sparing salvage therapy for multidrug-resistant HIV-1 infection based on new-class and new-generation antiretrovirals.
Efficacy and tolerability of long-term efavirenz plus nucleoside reverse transcriptase inhibitors for HIV-1 infection.
Elevated PD-1 expression and decreased telomerase activity in memory T cells of patients with symptomatic Herpes Zoster infection.
Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate single-tablet regimen (Stribild®): a review of its use in the management of HIV-1 infection in adults.
Emerging antiviral drugs.
Emerging Pharmacology: Inhibitors of Human Immunodeficiency Virus Integration.
Emtricitabine/Tenofovir Disoproxil Fumarate: In Combination with a Protease Inhibitor in HIV-1 Infection.
Epidemiological investigation of nine respiratory pathogens in hospitalized children in Germany using multiplex reverse-transcriptase polymerase chain reaction.
Epigallocatechin-3-Gallate, the Main Polyphenol in Green Tea, Inhibits Porcine Epidemic Diarrhea Virus In Vitro.
Eradication of human immunodeficiency virus type 1-infected cells by a combination of antimetabolic cytotoxic chemotherapy and antiviral chemotherapy in vitro: a pilot study.
Establishing Renal Proximal Tubule Epithelial-Derived Cell Lines Expressing Human Telomerase Reverse Transcriptase for Studying BK Polyomavirus.
Establishment and analysis of the prediction model for cervical squamous cell carcinoma.
Establishment of an immortalised human ovarian surface epithelial cell line without chromosomal instability.
Establishment of an immortalized human extravillous trophoblast cell line by retroviral infection of E6/E7/hTERT and its transcriptional profile during hypoxia and reoxygenation.
Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancer.
Evidence against the involvement of nitric oxide in the modulation of telomerase activity or replicative capacity of human endothelial cells.
Experience of an Orthopaedic Surgery Department Early During the COVID-19 Outbreak in Japan Including Real-Time Polymerase Chain Reaction Assay Results for SARS-CoV-2.
Experience With Pretravel Testing for SARS-CoV-2 at an Academic Medical Center.
Expression of baboon endogenous virus in exogenously infected baboon cells.
Expression of Candida albicans secreted aspartyl proteinase in acute vaginal candidiasis.
Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts.
Expression of human telomerase RNA is an early event of stomach carcinogenesis.
False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases.
Fatal West Nile Virus infection after rituximab/fludarabine--induced remission for non-Hodgkin's lymphoma.
Five years' experience of reverse-transcriptase polymerase chain reaction in daily diagnosis of enterovirus and rhinovirus infections.
Frequent detection of human coronaviruses in clinical specimens from patients with respiratory tract infection by use of a novel real-time reverse-transcriptase polymerase chain reaction.
Frequent incorporation of Ribonucleotides during HIV-1 reverse transcription and their attenuated repair in macrophages.
Full-Genome Analysis of Hepatitis C Virus in Japanese and Non-Japanese Patients Coinfected With HIV-1 in Tokyo.
Function of PRRSV GP5 envelope protein by using pseudotyped virus.
Functional assessment of pharmacological telomerase activators in human T cells.
Gastric Sonic Hedgehog Acts as a Macrophage Chemoattractant During the Immune Response to Helicobacter pylori.
Gene expression profiling of a compatible interaction between Douglas-Fir and the root rot fungal pathogen Phellinus sulphurascens.
HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes.
Helicobacter pylori and telomerase activity in intestinal metaplasia of the stomach.
Helicobacter pylori infection and carcinogenesis of the stomach.
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.
Helicobacter pylori infection induces telomerase activity in premalignant lesions.
Helicobacter pylori infection: augmentation of telomerase activity in cancer and noncancerous tissues.
Hepatic involvement as Hyperbilirubinemia in Patients with COVID-19: Case Series from Iran.
Hepatitis B Virus (HBV) Infection and Re-activation During Nucleos(t)ide Reverse Transcriptase Inhibitor-Sparing Antiretroviral Therapy in a High-HBV Endemicity Setting.
Hepatitis B Virus preS/S Truncation Mutant rtM204I/sW196* Increases Carcinogenesis through Deregulated HIF1A, MGST2, and TGFbi.
Hepatitis B virus X gene induces human telomerase reverse transcriptase mRNA expression in cultured normal human cholangiocytes.
Hepatitis C virus may infect extrahepatic tissues in patients with hepatitis C.
Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells.
High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil.
Higher rates of triple-class virological failure in perinatally HIV-infected teenagers compared with heterosexually infected young adults in Europe.
Highly sensitive detection and localization of maternally acquired human cytomegalovirus in placental tissue by in situ polymerase chain reaction.
HIV Reverse-Transcriptase Drug Resistance Mutations During Early Infection Reveal Greater Transmission Diversity Than in Envelope Sequences.
HIV-1 Gag-Pol Sequences from Ugandan Early Infections Reveal Sequence Variants Associated with Elevated Replication Capacity.
HIV-1 Induces Telomerase Activity in Monocyte-Derived Macrophages, Possibly Safeguarding One of Its Reservoirs.
HIV-1 infection downregulates nuclear telomerase activity on lymphoblastoic cells without affecting the enzymatic components at the transcriptional level.
HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.
HIV-1 Vif-derived peptide inhibits drug-resistant HIV proteases.
HIV-associated lipodystrophy syndrome.
HIV-reverse transcriptase inhibition: inclusion of ligand-induced fit by cross-docking studies.
HLA-B*5701 testing to predict abacavir hypersensitivity.
Hospitalization due to human parainfluenza virus-associated lower respiratory tract illness in rural Thailand.
hTERT Inhibition Triggers Epstein-Barr Virus Lytic Cycle and Apoptosis in Immortalized and Transformed B Cells: A Basis for New Therapies.
hTERT Protein Expression in Cytoplasm and Nucleus and its Association With HPV Infection in Patients With Cervical Cancer.
Human immunodeficiency virus (HIV) Type 1 reverse transcriptase resistance mutations in hepatitis B virus (HBV)-HIV-coinfected patients treated for HBV chronic infection once daily with 10 milligrams of adefovir dipivoxil combined with lamivudine.
Human immunodeficiency virus type 1 infection requires reverse transcription of nascent viral RNA.
Human immunodeficiency virus type 1 modulates telomerase activity in peripheral blood lymphocytes.
Human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns among treatment-naive patients in different stages of infection in Rio de Janeiro, Brazil.
Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients.
Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression.
Human telomerase gene amplification and high-risk human papillomavirus infection in women with cervical intra-epithelial neoplasia.
Identification of hantavirus infection by Western blot assay and TaqMan PCR in patients hospitalized with acute kidney injury.
IL-4 is protective against development of toxoplasmic encephalitis.
Immortalization of ameloblastoma cells via reactivation of telomerase function: Phenotypic and molecular characteristics.
Immortalization of Fetal Bovine Colon Epithelial Cells by Expression of Human Cyclin D1, Mutant Cyclin Dependent Kinase 4, and Telomerase Reverse Transcriptase: An In Vitro Model for Bacterial Infection.
Immune stimulatory and anti-HIV-1 potential of extracts derived from marine brown algae Padina tetrastromatica.
Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer.
Impact of indinavir on the quality of life in patients with advanced HIV infection treated with zidovudine and lamivudine.
Impact of modulation of telomerase and cancer stem-cell marker OCT4 axis in cervical cancer pathogenesis with underlying HPV16 infection.
Improvement in neutrophil and monocyte function during highly active antiretroviral treatment of HIV-1-infected patients.
In vitro effect of some nucleoside reverse transcriptase inhibitors against HSV-1 replication.
In vitro evaluation of the anti-HIV activity and metabolic interactions of tenofovir and emtricitabine.
In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA.
Incidence and risk factors for Dengue virus (DENV) infection in the first 2 years of life in a Brazilian prospective birth cohort.
Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy.
Increased in vitro glial fibrillary acidic protein expression, telomerase activity, and telomere length after productive human immunodeficiency virus-1 infection in murine astrocytes.
Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response.
Induction of telomerase activity in v-myc-transformed avian cells.
Infection of synoviocytes with HTLV-I induces telomerase activity.
Infectivity of human T-lymphotropic virus type I to human nervous tissue cells in vitro.
Influence of Piperine on the Pharmacokinetics of Nevirapine under Fasting Conditions : A Randomised, Crossover, Placebo-Controlled Study.
Inhibition of HIV-1 replication in human primary cells by a dolabellane diterpene isolated from the marine algae Dictyota pfaffii.
Insufficient PINX1 expression stimulates telomerase activation by direct inhibition of EBV LMP1-NF-?B axis during nasopharyngeal carcinoma development.
Intensive care unit patients with 2009 pandemic influenza A (H1N1pdm09) virus infection - United States, 2009.
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Interactions between non-nucleoside reverse transcriptase inhibitor and nucleoside reverse transcriptase inhibitor mutations: phenotypes and mechanisms.
Interference of cell cycle progression by zidovudine and lamivudine in NIH 3T3 cells.
Intracellular pharmacokinetic study of zidovudine and its phosphorylated metabolites.
Intracellular phosphorylation of zidovudine (ZDV) and other nucleoside reverse transcriptase inhibitors (RTI) used for human immunodeficiency virus (HIV) infection.
Intranasal immunization with HIV reverse transcriptase: effect of dose in the induction of helper T cell type 1 and 2 immunity.
Islatravir in combination with doravirine for treatment-naive adults with HIV-1 infection receiving initial treatment with islatravir, doravirine, and lamivudine: a phase 2b, randomised, double-blind, dose-ranging trial.
Isolation and characterization of human gastric cell lines with stem cell phenotypes.
Isolation and characterization of the Candida albicans MOT2 gene.
Isolation and propagation of HIV-1 on peripheral blood mononuclear cells.
La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication.
Lack of detection of enteroviral RNA or bacterial DNA in magnetic resonance imaging-directed muscle biopsies from twenty children with active untreated juvenile dermatomyositis.
Lamivudine for the treatment of HIV.
Long-term changes in adipose tissue in human disease.
Long-term efficacy of dual nucleoside reverse transcriptase inhibitor antiretroviral therapy in HIV-1 infection.
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase.
Lung pathology of fatal severe acute respiratory syndrome.
Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase.
Maternal and perinatal outcomes and placental pathologic examination of 29 SARS-CoV-2 infected patients in the third trimester of gestation.
Maternal immune responses and risk of infant infection with HIV-1 after a short course Zidovudine in a cohort of HIV-1 infected pregnant women in rural Kenya.
Mathematical Modelling of the Molecular Mechanisms of Interaction of Tenofovir with Emtricitabine against HIV.
Measurement of telomerase activity in bovine leukaemia virus infected cows.
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs.
Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors.
Meteorological conditions and land cover as predictors for the prevalence of Bluetongue virus in the Inner Mongolia Autonomous Region of Mainland China.
Microbiome of the wasp Vespula pensylvanica in native and invasive populations, and associations with Moku virus.
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.
Minus-strand DNA is present within murine type C ecotropic retroviruses prior to infection.
Mirl is highly upregulated and localized to nuclei during infectious hyphal growth in the rice blast fungus.
Mitochondrial pathway of apoptosis and necrosis contribute to tenofovir disoproxil fumarate-induced renal damage in rats.
Mitochondrial T9098C sequence change in the MTATP6 gene and development of severe mitochondrial disease after in utero antiretroviral prophylaxis.
Mobile and accurate detection system for infection by the 2009 pandemic influenza A (H1N1) virus with a pocket-warmer reverse-transcriptase loop-mediated isothermal amplification.
Moderate Hepatic Impairment Does Not Affect Doravirine Pharmacokinetics.
Modulation of telomerase activity, bTERT and c-Myc induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin during Bovine Herpesvirus 1 infection in MDBK cells.
Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors.
Molecular biology of gastric carcinoma: from laboratory to bedside.
Molecular characterization and functional analysis of IL-12p40 from Chinese sea bass (Lateolabrax maculatus) under biotic and abiotic stresses.
Molecular mechanism of human stomach carcinogenesis implicated in Helicobacter pylori infection.
Molecular virology of hepatitis B virus and targets for antiviral intervention.
Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine.
Multiple-dose pharmacokinetics of apricitabine, a novel nucleoside reverse transcriptase inhibitor, in patients with HIV-1 infection.
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate.
Mutational analysis of the "turn" of helix clamp motif of HIV-1 reverse transcriptase.
Mycobacterium tuberculosis Mce1 protein complex initiates rapid induction of transcription of genes involved in substrate trafficking.
Naringin improves zidovudine- and stavudine-induced skeletal muscle complications in rats.
Neurokinin-1 receptor antagonist (aprepitant) inhibits drug-resistant HIV-1 infection of macrophages in vitro.
Neutralizing Antibody Responses After SARS-CoV-2 Infection in End-Stage Kidney Disease and Protection Against Reinfection.
Nevirapine plus efavirenz plus didanosine: a simple, safe, and effective once-daily regimen for patients with HIV infection.
Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives.
Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability.
Non-nucleoside reverse transcriptase inhibitors: perspectives on novel therapeutic compounds and strategies for the treatment of HIV infection.
Normal T-cell telomerase activity and upregulation in human immunodeficiency virus-1 infection.
Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment.
Nucleoside analogue mutations and Q151M in HIV-1 subtype A/E infection treated with nucleoside reverse transcriptase inhibitors.
Nucleoside reverse transcriptase inhibitor toxicity and mitochondrial DNA.
Nucleoside reverse transcriptase inhibitors (NRTIs)-induced expression profile of mitochondria-related genes in the mouse liver.
Oral EBV and KSHV infection in HIV.
Overexpression of the HIV-1 gag-pol polyprotein results in intracellular activation of HIV-1 protease and inhibition of assembly and budding of virus-like particles.
Oxazole-Benzenesulfonamide Derivatives Inhibit HIV-1 Reverse Transcriptase Interaction with Cellular eEF1A and Reduce Viral Replication.
Pandemic influenza A (H1N1) 2009: chest radiographic findings from 147 proven cases in the Montreal area.
Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Pathology and viral distribution in fatal Usutu virus infections of birds from the 2001 and 2002 outbreaks in Austria.
Patterns of Influenza Vaccination and Vaccine Effectiveness Among Young US Children Who Receive Outpatient Care for Acute Respiratory Tract Illness.
Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina.
Peripheral Neuropathy in HIV: An Analysis of Evidence-based Approaches.
Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.
Pharmacokinetic evaluation of the effects of ribavirin on zidovudine triphosphate formation: ACTG 5092s Study Team.
Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects.
Pharmacological and clinical evidence of nevirapine immediate- and extended-release formulations.
Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages.
Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.
Population pharmacokinetics of nevirapine in Malaysian HIV patients: a non-parametric approach.
Possible involvement of loss of imprinting in immortalization of human fibroblasts.
Potent activity of a nucleoside reverse transcriptase inhibitor, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice.
Potent Inhibition of HIV-1 Replication in Resting CD4 T Cells by Resveratrol and Pterostilbene.
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases.
Presence of HIV-1 reverse transcriptase inhibitory antibodies in the sera of some HTLV-1 carriers and absence of neutralizing antibodies against HIV-1 in the sera of HTLV-1 carriers.
Prevalence and clinical features of pneumonia in patients with laboratory-confirmed pandemic influenza A H1N1 2009 infection in South Korea.
Prevalence of HIV-1 resistant strains in recent seroconverters.
Prevalence of positive COVID-19 among asymptomatic health care workers who care patients infected with the novel coronavirus: A retrospective study.
Prevalence of pretreatment and acquired HIV-1 mutations associated with resistance to lamivudine or rilpivirine: a systematic review.
Prevalence of transmitted nucleoside analogue-resistant HIV-1 strains and pre-existing mutations in pol reverse transcriptase and protease region: outcome after treatment in recently infected individuals.
PRINCE-1: safety and efficacy of atazanavir powder and ritonavir liquid in HIV-1-infected antiretroviral-naïve and -experienced infants and children aged ?3 months to <6 years.
Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.
Properties of oncornavirus RNA-directed DNA polymerase, the RNA template, and the intracellular products formed early during infection and cell transformation.
Prospective comparison of the detection rates of human enterovirus and parechovirus RT-qPCR and viral culture in different pediatric specimens.
Purification and further characterization of an RNA-dependent DNA polymerase from the allantoic fluid of leukosis-virus-free chicken eggs.
Quantitative determination of abacavir (1592U89), a novel nucleoside reverse transcriptase inhibitor, in human plasma using isocratic reversed-phase high-performance liquid chromatography with ultraviolet detection.
Quantitative measurement of telomerase activity in lymphadenopathy: correlation with histologic features and human immunodeficiency virus-1 infection.
Raltegravir and Abacavir/Lamivudine in Japanese Treatment-Naïve and Treatment-Experienced Patients with HIV Infection: a 48-Week Retrospective Pilot Analysis.
Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity.
Recent advances in the diagnosis and treatment of influenza pneumonia.
Recombinant adenovirus infection suppresses hTERT expression through virus-associated RNA-mediated induction of type 1 interferon.
Relationship between in vitro human immunodeficiency virus type 1 replication rate and virus load in plasma.
Relationship between the expression of telomerase and human papillomavirus infection in invasive uterine cervical carcinoma.
Relative assessment of different statistical instruments and measures for the prediction of promising outcomes using docking, virtual screening and ADMET analysis against HIV-RT.
Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development.
Resistance to nonnucleoside reverse-transcriptase inhibitors and prevalence of HIV type 1 non-B subtypes are increasing among persons with recent infection in Spain.
Respiratory syncytial virus infection and the tight junctions of nasal epithelial cells.
Respiratory syncytial virus infection in elderly and high-risk adults.
Response to efavirenz plus two nucleoside reverse-transcriptase inhibitors in patients with advanced stage human immunodeficiency virus-1 infection in Taiwan.
Retinal Pigment Epithelial Cells Control Early Mycobacterium tuberculosis Infection via Interferon Signaling.
Retroviral-mediated expression of telomerase in normal human cells provides a selective growth advantage.
Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells.
Rickettsia parkeri colonization in Amblyomma maculatum: the role of superoxide dismutases.
Role for telomerase in Listeria monocytogenes infection.
Safety analysis of Ziagen® (abacavir sulfate) in postmarketing surveillance in Japan.
Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women.
Safety and Efficacy of Ziagen (Abacavir Sulfate) in HIV-Infected Korean Patients.
Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
Separation methods for nucleoside analogues used for treatment of HIV-1 infection.
Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study.
Severe skin rash with lamivudine in HIV infected patients: some unusual case reports.
siRNA-mediated inhibition of hTERT enhances chemosensitivity of hepatocellular carcinoma.
Spontaneous Mutations in HIV-1 Gag, Protease, RT p66 in the First Replication Cycle and How They Appear: Insights from an In Vitro Assay on Mutation Rates and Types.
Steatohepatitis in HIV-infected subjects: pathogenesis, clinical impact and implications in clinical management.
Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.
Structure-activity relationship studies on clinically relevant HIV-1 NNRTIs.
Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
Subcellular Localization of HIV-1 gag-pol mRNAs Regulates Sites of Virion Assembly.
Suppression of human immunodeficiency virus replication in human brain tissue by nucleoside reverse transcriptase inhibitors.
SV40 infection induces telomerase activity in human mesothelial cells.
Synergistic antiviral effect of PEG-asparaginase (ONCASPAR), with protease inhibitor alone and in combination with RT inhibitors against HIV-1 infected T-cells: a model of HIV-1-induced T-cell lymphoma.
T cell telomere length in HIV-1 infection: no evidence for increased CD4+ T cell turnover.
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Telomerase activity and expression of its RNA component in cervical lesions.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer.
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA.
Telomerase activity impacts on Epstein-Barr virus infection of AGS cells.
Telomerase activity in response to mild oxidative stress.
Telomerase activity in tumor and remnant liver as predictor of recurrence and survival in hepatocellular carcinoma after resection.
Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors.
Telomerase activity of human peripheral blood mononuclear cells in the course of HTLV type 1 infection in vitro.
Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4(+) T lymphocytes infected with human immunodeficiency virus type 1 (HIV-1).
Telomerase immortalization of human myometrial cells.
Telomerase Induction in HPV Infection and Oncogenesis.
Telomerase protects adult rodent olfactory ensheathing glia from early senescence.
Telomerase protects cancer-prone human cells from chromosomal instability and spontaneous immortalization.
Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With Felis catus Papillomavirus Type-2 Infection.
Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections.
Telomerase therapeutics for degenerative diseases.
Telomerase, p53 and human papillomavirus infection in the uterine cervix.
Telomerase--a potential molecular marker of lung and cervical cancer.
Telomerase-A molecular marker for cervical cancer screening.
Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.
Telomere length, telomerase activity, and replicative potential in HIV infection: analysis of CD4+ and CD8+ T cells from HIV-discordant monozygotic twins.
Telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells.
The "Connection" Between HIV Drug Resistance and RNase H.
The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitro.
The combination of abundance and infection rates of Culicoides sonorensis estimates risk of subsequent bluetongue virus infection of sentinel cattle on California dairy farms.
The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes.
The Human Cytomegalovirus Strain DB Activates Oncogenic Pathways in Mammary Epithelial Cells.
The human immunodeficiency virus type 1 carboxyl-terminal third of capsid sequence in Gag-Pol is essential but not sufficient for efficient incorporation of Pr160(gag-pol) into virus particles.
The isoform-specific functions of the c-Jun N-terminal kinase (JNK) in a mouse model of antiretroviral-induced painful peripheral neuropathy.
The optimal diagnostic methods for COVID-19.
The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels.
The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy.
The role of human telomerase catalytic subunit mRNA expression in cervical dysplasias.
The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.
The role of previous infection of hepatitis B virus in Hbs antigen negative and anti-HCV negative Japanese patients with hepatocellular carcinoma: etiological and molecular biological study.
The secrets of telomerase: Retrospective analysis and future prospects.
The Telomerase Inhibitor MST-312 Interferes with Multiple Steps in the Herpes Simplex Virus Life Cycle.
The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit.
The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.
Timing, Complications, and Safety of Tracheotomy in Critically Ill Patients With COVID-19.
TNF? is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats.
Tomographic score (RAD-Covid Score) to assess the clinical severity of the novel coronavirus infection.
Topical administration of low-dose tenofovir disoproxil fumarate to protect infant macaques against multiple oral exposures of low doses of simian immunodeficiency virus.
Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus.
Transmission dynamics of SARS-CoV-2 within families with children in Greece: A study of 23 clusters.
Transmission of antiretroviral-drug-resistant HIV-1 variants.
Transmitted Drug Resistance Mutations in Antiretroviral-Naïve Injection Drug Users with Chronic HIV-1 Infection in Iran.
Transplantation of normal and DMD myoblasts expressing the telomerase gene in SCID mice.
Treatment of HIV-1-associated microsporidiosis and cryptosporidiosis with combination antiretroviral therapy.
Treatment outcomes after highly active antiretroviral therapy: a meta-analysis of randomised controlled trials.
Tricyclononene carboxamide derivatives as novel anti-HIV-1 agents.
Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection.
Two low doses of tenofovir protect newborn macaques against oral simian immunodeficiency virus infection.
Up-regulation of two Candida albicans genes in the rat model of oral candidiasis detected by differential display.
Upregulated miR-155 inhibits inflammatory response induced by C. albicans in human monocytes derived dendritic cells via targeting p65 and BCL-10.
Use of probes and amplification techniques for the diagnosis and prognosis of human immunodeficiency virus (HIV-1) infections.
Variable proteolytic cleavage of gag precursor expressed after infection of several cell lines with an HIV-2 gag-pol recombinant vaccinia virus.
Variations of telomerase activity in cultured mouse fibroblasts upon proliferation of polyomavirus.
Viral dynamics of early HIV infection in neonatal macaques after oral exposure to HIV-2287: an animal model with implications for maternal-neonatal HIV transmission.
Viral etiology of respiratory infections in children in southwestern Saudi Arabia using multiplex reverse-transcriptase polymerase chain reaction.
Viral load as a predictor of outcome in Crimean-Congo hemorrhagic fever.
Virulence gene transcription, phylogroups, and antibiotic resistance of cervico-vaginal pathogenic E. coli in Mexico.
White blood cell telomerase activity and incident respiratory illness among community-dwelling elderly vaccinated against seasonal influenza.
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
Zika virus in semen: a prospective cohort study of symptomatic travellers returning to Belgium.
[Amplification and clinical significance of hTERC gene in the cervical exfoliated cells from natural population in Shenzhen]
[Anti-HIV drugs and drug delivery system]
[Coordinated expression of c-Myc and telomerase activity in Helicobacter pylori infected gastric diseases]
[Detection and significance of HPV16, 18 infection, P53 overexpression and telomerase activity in patients with lung cancer]
[Drug clinics. How I treat HIV infections. II. Nucleoside reverse transcriptase inhibitors]
[Expression of human immunodeficiency virus gag antigens and formation of virus-like particles in a cell culture, infected with recombinant vaccinia virus strains (an electron-microscopic study)]
[Functional changes of dendritic cells after infection by recombinant retrovirus carrying human telomerase reverse transcriptase gene fragment]
[Inhibitory effect of RNAi targeting human telomerase reverse transcriptase against human hepatocellular carcinoma cells]
[Pharma-clinics. The drug of the month. Nevirapine. Viramune]
[Relationship among HPV16 infection and Expression of hTERT, p21waf1, Ki67 in cervical intraepithelial neoplasias and squamous cell carcinomas of cervix uteri]
[Relationship between human papillomavirus 16 infection and the expression of p33(ING1b), human telomerase reverse transcriptase in cervical squamous cell carcinoma of Uygur female in Xinjiang Uygur Autonomous Region]
[Research on expression of human papillomavirus type 16 and telomerase in oral lesions]
[Significance of modern methods for laboratory detection of rabies agents and identification of the zoonose immunological survey].
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
[Study on the correlation between the different papillomavirus type and telomerase in cervical cancer]
[Telomerase activity in cervical carcinoma and cervical intraepithelial neoplasia and its correlation to classification of koilocytosis]
[Telomerase, cell immortality and cancer]
[Two patients with novel influenza A virus (H1N1) pneumonia treated with steroid therapy after an incorrect diagnosis of rapid progressive interstitial pneumonia due to the negative results of a rapid-antigen test].
Infertility
Does telomerase activity have an effect on infertility in patients with endometriosis?
Does telomerase activity have an effect on infertility in patients with endometriosis? Methodological issues.
Implications of telomeres and telomerase in endometrial pathology.
Investigation of the role of serum telomerase levels in patients with occult primary ovarian insufficiency: a prospective cross-sectional study.
Letter from original author re. Does telomerase activity have an effect on infertility in patients with endometriosis? Methodological issues.
Mathematical model to study the aging of the human follicle according to the telomerase activity.
Mesenchymal Stem/Stromal Cell Production Compliant with Good Manufacturing Practice: Comparison between Bone Marrow, the Gold Standard Adult Source, and Wharton's Jelly, an Extraembryonic Source.
Ovarian Telomerase and Female Fertility.
Stem cell factor activates telomerase in mouse mitotic spermatogonia and in primordial germ cells.
Telomerase activity and expression of telomerase subunits in the testicular tissue of infertile patients.
Telomerase activity in pregnancy complications (Review).
Infertility, Female
Exome sequencing identifies mutant TINF2 in a family with pulmonary fibrosis.
Fertility, IVF and reproductive genetics.
Telomere length and telomerase activity during folliculogenesis in mammals.
Infertility, Male
Genetic variants in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) and the risk of male infertility.
Telomerase activity and telomere length in male germ cells.
TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B[a]P in vivo.
Inflammatory Bowel Diseases
Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications.
Expression of endothelial protein C receptor and thrombomodulin in the intestinal tissue of patients with inflammatory bowel disease.
Lymphocyte telomere dynamics and telomerase activity in inflammatory bowel disease: effect of drugs and smoking.
Motilin receptor expression in smooth muscle, myenteric plexus, and mucosa of human inflamed and noninflamed intestine.
Strong telomerase activity of B lymphocyte from mesenteric lymph nodes of patients with inflammatory bowel disease.
Telomerase activity in chronic inflammatory bowel disease.
Telomerase mRNA expression and immunohistochemical detection as a biomarker of malignant transformation in patients with inflammatory bowel disease.
Ulcerative Typhlocolitis Associated With Helicobacter mastomyrinus in Telomerase-Deficient Mice.
Influenza in Birds
Avian influenza surveillance in hunter-harvested waterfowl from the Gulf Coast of Texas (November 2005-January 2006).
Development of a multiplex real-time PCR assay using SYBR Green 1 chemistry for simultaneous detection and subtyping of H9N2 influenza virus type A.
Proceedings Paper-Avian Diseases 10th AI Symposium Issue Development and Application of Real-Time PCR Assays for Specific Detection of Contemporary Avian Influenza Virus Subtypes N5, N6, N7, N8, and N9.
Use of FTA sampling cards for molecular detection of avian influenza virus in wild birds.
Influenza, Human
2015-2016 Vaccine Effectiveness of Live Attenuated and Inactivated Influenza Vaccines in Children in the United States.
A Multiplex RT-PCR Assay for Detection and Differentiation of Avian-Origin Canine H3N2, Equine-Origin H3N8, Human-Origin H3N2, and H1N1/2009 Canine Influenza Viruses.
Active fulminant myocarditis characterized by T-lymphocytes expressing the gamma-delta T-cell receptor: a new disease entity?
Active surveillance for avian influenza virus infection in wild birds by analysis of avian fecal samples from the environment.
Amplification of the entire genome of influenza A virus H1N1 and H3N2 subtypes by reverse-transcription polymerase chain reaction.
An algorithm for mapping positively selected members of quasispecies-type viruses.
Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus.
Approved Antiviral Drugs over the Past 50 Years.
Association of Human Metapneumovirus with Radiologically Diagnosed Community-Acquired Alveolar Pneumonia in Young Children.
Characterization of HeLa cells persistently infected with influenza virus B/Lee/40 with respect to telomerase activity and apoptosis.
Characterization of influenza virus among influenza like illness cases in Mumbai, India.
Clinical and Demographic Characteristics of Confirmed Cases in H1N1 (2009) Influenza.
Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: Experience from multiple tertiary paediatric centres in Turkey.
Clinical decision making in the emergency department setting using rapid PCR: Results of the CLADE study group.
Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS-CoV-2 agents?
Comparison of influenza vaccine effectiveness using different methods of case detection: clinician-ordered rapid antigen tests vs. active surveillance and testing with real-time reverse-transcriptase polymerase chain reaction (rRT-PCR).
Comparison of the Safety and Immunogenicity of 2 Respiratory Syncytial Virus (RSV) Vaccines- Nonadjuvanted Vaccine or Vaccine Adjuvanted with Alum-Given Concomitantly with Influenza Vaccine to High-Risk Elderly Individuals.
Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006-2007.
Critically ill children with pandemic influenza (H1N1) in pediatric intensive care units in Turkey.
Detection of highly pathogenic zoonotic influenza virus H5N6 by reverse-transcriptase quantitative polymerase chain reaction.
Detection of influenza C virus by a real-time RT-PCR assay.
Development of a novel real-time reverse-transcriptase PCR method for the detection of H275Y positive influenza A H1N1 isolates.
Development of Anti-Viral Agents Using Molecular Modeling and Virtual Screening Techniques.
Development of anti-viral agents using molecular modeling and virtual screening techniques.
Discovery of dapivirine, a nonnucleoside HIV-1 reverse transcriptase inhibitor, as a broad-spectrum antiviral against both influenza A and B viruses.
DNA chain termination activity and inhibition of human immunodeficiency virus reverse transcriptase by carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine triphosphate.
Effect of antigenic drift on influenza vaccine effectiveness in the United States - 2019-2020.
Effectiveness of inactivated influenza vaccines varied substantially with antigenic match from the 2004-2005 season to the 2006-2007 season.
Effectiveness of influenza vaccination of schoolchildren in the city of São Paulo, Brazil, 2009.
Effectiveness of Live Attenuated vs Inactivated Influenza Vaccines in Children During the 2012-2013 Through 2015-2016 Influenza Seasons in Alberta, Canada: A Canadian Immunization Research Network (CIRN) Study.
Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older.
Epidemiology of Influenza in Fars Province, Southern Iran; a Population-Based Study (2015-2019).
Failure of routine diagnostic methods to detect influenza in hospitalized older adults.
Field performance of a rapid diagnostic test for influenza in an ambulatory setting.
First Fatal Oseltamivir-Resistant 2009 Pandemic Influenza A (H1N1) Case in an Adult in Korea.
Free energy mapping of class I MHC molecules and structural determination of bound peptides.
Frequencies of tetramer+ T cells specific for the wild-type sequence p53(264-272) peptide in the circulation of patients with head and neck cancer.
Frozen Master Mix Modification of Commercial Reverse-transcriptase PCR for Detection of Influenza and Respiratory Syncytial Viruses.
Genetic analysis of H1N1 influenza virus from throat swab samples in a microfluidic system for point-of-care diagnostics.
H1N1 2009 influenza virus infection during pregnancy in the USA.
H5N1 influenza virus-like particles produced by transient expression in mammalian cells induce humoral and cellular immune responses in mice.
Impact of human metapneumovirus in childhood: comparison with respiratory syncytial virus and influenza viruses.
In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.
In-silico profiling of the biological activities of Amaryllidaceae alkaloids.
Incidence and Risk Factors of Pneumonia in Hospitalized Patients with Seasonal Influenza A or B.
Influenza epidemiology and characterization of influenza viruses in patients seeking treatment for acute fever in Cambodia.
Mobile and accurate detection system for infection by the 2009 pandemic influenza A (H1N1) virus with a pocket-warmer reverse-transcriptase loop-mediated isothermal amplification.
Neurologic Manifestations of Novel Influenza A (H1N1) Virus Infection in Childhood.
One-Step Multiplex Reverse-Transcriptase PCR for Detecting Pandemic (H1N1) 2009 Influenza Virus.
Pandemic influenza A (H1N1) 2009: chest radiographic findings from 147 proven cases in the Montreal area.
Patterns of Influenza Vaccination and Vaccine Effectiveness Among Young US Children Who Receive Outpatient Care for Acute Respiratory Tract Illness.
Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina.
Performance of a rapid influenza test in children during the H1N1 2009 influenza a outbreak.
Prevalence and distribution of avian influenza a(H5N1) virus clade variants in live bird markets of Vietnam, 2011-2013.
Recent advances in the diagnosis and treatment of influenza pneumonia.
Reduction in the Incidence of Influenza A But Not Influenza B Associated With Use of Hand Sanitizer and Cough Hygiene in Schools: A Randomized Controlled Trial.
Relapse of minimal change disease following infection with the 2009 pandemic influenza (H1N1) virus.
Report of two rare complications of pandemic influenza A (H1N1).
Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness.
Respiratory syncytial virus infection in elderly and high-risk adults.
Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study.
Spread of Antigenically Drifted Influenza A(H3N2) Viruses and Vaccine Effectiveness in the United States During the 2018-2019 Season.
Switching gears for an influenza pandemic: validation of a duplex RT-PCR for simultaneous detection and confirmation of pandemic (H1N1) 2009.
T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx.
The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children, 2000-2005.
The clinical usefulness of the SD Bioline Influenza Antigen Test® for detecting the 2009 influenza A (H1N1) virus.
The Extent of Aspergillosis in Critically Ill Patients With Severe Influenza Pneumonia: A Multicenter Cohort Study.
The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes.
The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects.
The use of equine influenza pseudotypes for serological screening.
Underdiagnosis of Influenza Virus Infection in Hospitalized Older Adults.
Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults.
White blood cell telomerase activity and incident respiratory illness among community-dwelling elderly vaccinated against seasonal influenza.
[A case of acute respiratory distress syndrome associated with pandemic influenza A (H1N1) pneumonia which was aggravated by the cessation of corticosteroid therapy].
[Advances in antiviral chemotherapy]
[Case of novel influenza A (H1N1) pneumonia with shrinkage of a pulmonary lesion].
[Clinical features and outcome of 2009 H1N1 influenza in the pediatric setting. Multicenter prospective study in the ED.]
[Two patients with novel influenza A virus (H1N1) pneumonia treated with steroid therapy after an incorrect diagnosis of rapid progressive interstitial pneumonia due to the negative results of a rapid-antigen test].
Insulin Resistance
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Brief Report: Insulin Resistance Is Affected by Increased Levels of Plasma Lactate but not Mitochondrial Alterations in Skeletal Muscle in NRTI-Exposed HIV-Infected Patients.
Evaluation and management of dyslipidemia in patients with HIV infection.
Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy.
Improving Insulin Sensitivity via Activation of PPAR-{gamma} Increases Telomerase Activity in the Heart of OLETF rats.
Insulin Resistance and Diabetes in HIV Infection.
Insulin resistance in the HIV-infected population: the potential role of mitochondrial dysfunction.
Insulin sensitivity in multiple pathways is differently affected during zidovudine/lamivudine-containing compared with NRTI-sparing combination antiretroviral therapy.
Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab.
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
Nonalcoholic fatty liver disease in HIV-infected patients referred to a metabolic clinic: prevalence, characteristics, and predictors.
Of sound mind and body: depression, disease, and accelerated aging.
The Relationship between Vitamin D Status and HIV-Related Complications in HIV-infected Children and Young Adults.
[Side effects of antiretroviral therapy]
[Telomere biology and metabolic disorders: the role of insulin resistance and type 2 diabetes].
Insulinoma
Telomerase activity in pancreatic endocrine tumors.
Telomerase activity in pancreatic endocrine tumours: a potential marker for malignancy.
Intervertebral Disc Degeneration
Expression and significance of telomerase in the nucleus pulposus tissues of degenerative lumbar discs.
Intervention of rAAV-hTERT-Transducted Nucleus Pulposus Cells in Early Stage of Intervertebral Disc Degeneration: A Study in Canine Model.
Iron Overload
Increased hepatic telomerase activity in a rat model of iron overload: a role for altered thiol redox state?
Ischemic Stroke
Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2/STAT3-involved apoptosis and inflammatory pathways.
Joint Diseases
Telomerase activity in the synovial tissues of chronic inflammatory and non-inflammatory rheumatic diseases.
Keloid
Effect of wt-P53 protein on telomerase activity in keloid fibroblasts.
Effects of hTERT antisense oligodeoxynucleotide on cell apoptosis and expression of hTERT and bcl-2 mRNA in keloid fibroblasts.
Gene transfer into human keloid tissue with adeno-associated virus vector.
Modulation of collagen synthesis in keloid fibroblasts by silencing Smad2 with siRNA.
PAX5 activates telomerase activity and proliferation in keloid fibroblasts by transcriptional regulation of SND1, thus promoting keloid growth in burn-injured skin.
Telomere dynamics in keloids.
Telomere shortening may be associated with human keloids.
Wnt/?-Catenin Signaling Exacerbates Keloid Cell Proliferation by Regulating Telomerase.
Keratoacanthoma
Biological behavior of keratoacanthoma and squamous cell carcinoma: telomerase activity and COX-2 as potential markers.
Keratoconus
Characterization of a human corneal metalloproteinase inhibitor (TIMP-1).
Transforming Growth Factor-? Signaling Pathway Activation in Keratoconus.
Keratosis, Actinic
Telomerase activity in melanoma and non-melanoma skin cancer.
[Actinic keratoses]
Kidney Diseases
Aging in Fabry Disease: Role of Telomere Length, Telomerase Activity, and Kidney Disease.
Kidney Failure, Chronic
A retrospective evaluation of highly active antiretroviral therapy simplification in patients with end-stage renal disease receiving hemodialysis.
Lack of seronegative hepatitis C virus infections in patients with chronic renal failure.
Telomerase activity is decreased in peripheral blood mononuclear cells of hemodialysis patients.
[Telomerase activity of peripheral blood mononuclear cells in patients with acquired immune dysfunction]
Kidney Neoplasms
A multi-peptide, dual-adjuvant telomerase vaccine (GX301) is highly immunogenic in patients with prostate and renal cancer.
Inhibition of proliferation and induction of apoptosis in human renal carcinoma cells by anti-telomerase small interfering RNAs.
Modulation of telomerase activity by zinc in human prostatic and renal cancer cells.
Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics.
Telomerase activity and telomere length in human tumor cells with acquired resistance to anticancer agents.
Telomerase assay in renal cancer.
Telomerase in urological malignancy.
Klinefelter Syndrome
Use of a highly sensitive quantitative telomerase assay in intracytoplasmic sperm injection programmes for the treatment of 47,XXY non-mosaic Klinefelter men.
Laryngeal Neoplasms
Effect of silencing key proteins in telomerase mechanism and alternative lengthening of telomeres mechanism in laryngeal cancer cells.
Inhibition of human telomerase reverse transcriptase in hep-2 cells using short hairpin RNA expression vectors.
Inhibition of telomerase activity in cancer cells using short hairpin RNA expression vectors.
microRNA?299?3p inhibits laryngeal cancer cell growth by targeting human telomerase reverse transcriptase mRNA.
Potential clinical significance of perioperative levels of mRNA in plasma from patients with cancer of the larynx or hypopharynx.
Targeted therapy of human laryngeal squamous cell carcinoma in vitro by antisense oligonucleotides directed against telomerase reverse transcriptase mRNA.
Telomerase activity is upregulated in laryngeal squamous cell carcinoma.
The Telomerase and Alternative Lengthening of Telomeres Mechanisms Regulate Laryngeal Cancer Cell Apoptosis via the PI3K/Akt Pathway.
[Influence of RNA interference targeting against human telomerase reverse transcriptase on expression of C-myc protein]
[Inhibition of growth and proliferation of Hep-2 cells by targeting human telomerase reverse transcriptase mRNA using RNA interference technology]
[Telomerase activity and expression of its RNA component in laryngeal cancer]
Latent Infection
hTERT inhibits the Epstein-Barr virus lytic cycle and promotes the proliferation of primary B lymphocytes: implications for EBV-driven lymphomagenesis.
Insufficient PINX1 expression stimulates telomerase activation by direct inhibition of EBV LMP1-NF-?B axis during nasopharyngeal carcinoma development.
Latent membrane protein 1 of Epstein-Barr virus activates the hTERT promoter and enhances telomerase activity in B lymphocytes.
Lecithin Cholesterol Acyltransferase Deficiency
Lecithin: cholesterol acyltransferase deficiency: identification of two defective alleles in fibroblast cDNA.
Leiomyoma
Applications of the telomerase assay in peritoneal washing fluids.
Immortalization of human uterine leiomyoma and myometrial cell lines after induction of telomerase activity: molecular and phenotypic characteristics.
Karyotypic characteristics of human uterine leiomyoma and myometrial cell lines following telomerase induction.
Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium.
Telomerase activity in gynecologic tumors.
Telomerase activity in needle biopsied uterine myoma-like tumors: differential diagnosis between uterine sarcomas and leiomyomas.
Telomerase expression abrogates rapamycin-induced irreversible growth arrest of uterine fibroid smooth muscle cells.
Telomere shortening and expression of TRF1 and TRF2 in uterine leiomyoma.
Leiomyosarcoma
Mandibular central leiomyosarcoma with high telomerase activity: a case report.
Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.
Leishmaniasis
Leishmania amazonensis: Partial purification and study of the biochemical properties of the telomerase reverse transcriptase activity from promastigote-stage.
The putative Leishmania telomerase RNA (LeishTER) undergoes trans-splicing and contains a conserved template sequence.
Lentigo
Pigmentary disorders of the eyes and skin.
Leukemia
23-Hydroxybetulinic acid-mediated apoptosis is accompanied by decreases in bcl-2 expression and telomerase activity in HL-60 Cells.
A directed approach to improving the solubility of Moloney murine leukemia virus reverse transcriptase.
A G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells.
A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma.
A host-guest approach for determining drug-DNA interactions: an example using netropsin.
A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes.
A non-radioactive assay system for screening for inhibitors of RNA-dependent reverse transcriptase activity; an analysis using aurintricarboxylic acid and plant flavonoids.
A novel mechanism for inhibition of HIV-1 reverse transcriptase.
A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation.
A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias.
A novel ribonuclease with antiproliferative activity toward leukemia and lymphoma cells and HIV-1 reverse transcriptase inhibitory activity from the mushroom, Hohenbuehelia serotina.
A one-tube method of reverse transcription-PCR to efficiently amplify a 3-kilobase region from the RNA polymerase gene to the poly(A) tail of small round-structured viruses (Norwalk-like viruses).
A retroviral packaging cell line for pseudotype vectors based on glioma-infiltrating progenitor cells.
A small molecule compound IX inhibits telomere and attenuates oncogenesis of drug-resistant leukemia cells.
A stable platform for the production of virus-like particles pseudotyped with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein.
A study of the relationship between expression level of TRF1 protein and telomerase activity in human acute leukemia.
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways.
Activity of telomerase and extracellular regulated protein kinases in parental and drug resistant cells of leukemia and ovarian cancer.
Akt and PKC are involved not only in upregulation of telomerase activity but also in cell differentiation-related function via mTORC2 in leukemia cells.
Allosteric mechanism for translational repression in the Escherichia coli alpha operon.
Alterations in the response to erythropoietin and RNA-dependent DNA polymerase activity in mouse spleen cells infected with Friend leukemia virus.
Alternative lengthening of telomeres in hTERT-inhibited laryngeal cancer cells.
Alternative lengthening of telomeres in human glioma stem cells.
Alternative splicing of human telomerase reverse transcriptase may not be involved in telomerase regulation during all-trans-retinoic acid-induced HL-60 cell differentiation.
Amino acid substitutions away from the RNase H catalytic site increase the thermal stability of Moloney murine leukemia virus reverse transcriptase through RNase H inactivation.
Amino- and carboxyl-terminal sequence of Moloney murine leukemia virus reverse transcriptase.
Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase.
Amplification of sense-stranded prokaryotic RNA.
An enzymatically active chimeric HIV-1 reverse transcriptase (RT) with the RNase-H domain of murine leukemia virus RT exists as a monomer.
An Inulin-Specific Lectin with Anti-HIV-1 Reverse Transcriptase, Antiproliferative, and Mitogenic Activities from the Edible Mushroom Agaricus bitorquis.
Analysis of Moloney murine leukemia virus revertants mutated at the gag-pol junction.
Analysis of plus-strand primer selection, removal, and reutilization by retroviral reverse transcriptases.
Analysis of telomerase activity and RNA expression in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid.
Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase.
Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition.
Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells.
Antisense inhibition of human telomerase by phosphorothioate oligonucleotide-peptide conjugates.
Apigenin decreases cell viability and telomerase activity in human leukemia cell lines.
Arm-specific cleavage and mutation during reverse transcription of 2?,5?-branched RNA by Moloney murine leukemia virus reverse transcriptase.
Association of murine leukemia virus pol with virions, independent of Gag-Pol expression.
Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma.
Atypical protein-kinase Czeta, but neither conventional Ca2+ -dependent protein-kinase C isoenzymes nor Ca2+ -calmodulin, participates in regulation of telomerase activity in Burkitt's lymphoma cells.
Augmented telomerase activity, reduced telomere length and the presence of alternative lengthening of telomere in renal cell carcinoma: Plausible predictive and diagnostic markers.
Avian reticuloendotheliosis virus: characterization of genome structure by heteroduplex mapping.
Beauvericin and enniatins H, I and MK1688 are new potent inhibitors of human immunodeficiency virus type-1 integrase.
Berberine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of nucleophosmin/B23 and telomerase activity.
beta-Lapachone (LAPA) Decreases Cell Viability and Telomerase Activity in Leukemia Cells: Suppression of Telomerase Activity by LAPA.
beta-Lapachone: synthesis of derivatives and activities in tumor models.
Biosynthesis of reverse transcriptase from Rauscher murine leukemia virus by synthesis and cleavage of a gag-pol read-through viral precursor polyprotein.
Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells.
C-type RNA virus from hamster cells transformed in vitro by 1-B-D-arabinofuranosylcytosine.
Changes in telomerase activity and telomere length during human T lymphocyte senescence.
Characterization of an RNA-directed DNA polymerase found in association with murine intracytoplasmic A-particles.
Characterization of RNA strand displacement synthesis by Moloney murine leukemia virus reverse transcriptase.
Characterization of Telomerase (hTERT) in Solid and Hematopoietic Cancer Cell Lines Reveals Different Expression Patterns.
Chimeras between SRS and Moloney murine leukemia viruses reveal novel determinants in disease specificity and MCF recombinant formation.
Chimeric alpha-beta oligonucleotides as antisense inhibitors of reverse transcription.
cis Acting RNA sequences control the gag-pol translation readthrough in murine leukemia virus.
Clinical implications of telomerase activity levels in acute leukemia.
Clinical significance of telomerase genes (hTERC and hTERT) amplification in patients with acute myeloid leukemia.
Cloning and overexpression of Moloney murine leukemia virus reverse transcriptase in Escherichia coli.
Cloning, expression, and purification of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase: crystallization of nucleic acid complexes.
Coccinin, an antifungal peptide with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from large scarlet runner beans.
Coding sequences upstream of the human immunodeficiency virus type 1 reverse transcriptase domain in Gag-Pol are not essential for incorporation of the Pr160(gag-pol) into virus particles.
Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells.
Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.
Complete genome amplification of equine influenza virus subtype 2.
Compounds that enhance the tailing activity of Moloney murine leukemia virus reverse transcriptase.
Comprehensive in vitro analysis of simian retrovirus type 4 susceptibility to antiretroviral agents.
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection.
Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus.
Continuous high-titer HIV-1 vector production.
Contributory role of microRNAs in anti-cancer effects of small molecule inhibitor of telomerase (BIBR1532) on acute promyelocytic leukemia cell line.
Controlled intracellular localization and enhanced antisense effect of oligonucleotides by chemical conjugation.
Cordyceptin induces apoptosis through repressing hTERT expression and inducing extranuclear export of hTERT.
Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity.
Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.
Decreased Km to dNTPs is an essential M-MuLV reverse transcriptase adoption required to perform efficient cDNA synthesis in One-Step RT-PCR assay.
Defective herpes simplex virus type 1 vectors harboring gag, pol, and env genes can be used to rescue defective retrovirus vectors.
Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H.
Detection of human immunodeficiency virus type 1 reverse transcriptase using aptamers as probes in affinity capillary electrophoresis.
Detection of human telomerase reverse transcriptase mRNA in cells obtained by lavage of the pleura is not associated with worse outcome in patients with stage I/II non-small cell lung cancer: Results from Cancer and Leukemia Group B 159902.
Detection of naturally occurring antibodies to RNA-dependent DNA polymerase of murine leukemia virus in kidney eluates of AKR mice.
Determinants of Moloney murine leukemia virus Gag-Pol and genomic RNA proportions.
Development of a one tube-one step RT-PCR protocol for the detection of seven viroids in four genera: Apscaviroid, Hostuviroid, Pelamoviroid and Pospiviroid.
Development of a quantitative luminometric hybridization assay for the determination of telomerase activity.
Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus.
Diagnostic utility of a multiplex RT-PCR assay in detecting fusion transcripts from recurrent genetic abnormalities of acute leukemia by WHO 2008 classification.
Diagnostics, prognostic and therapeutic exploitation of telomeres and telomerase in leukemias.
Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines.
Differential effects of Moloney murine leukemia virus reverse transcriptase mutations on RNase H activity in Mg2+ and Mn2+.
Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells.
Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.
Distinct modulation of telomere length in two T-lymphoblastic leukemia cell lines by cytotoxic nucleoside phosphonates PMEG and PMEDAP.
DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts.
DNA polymerization by the reverse transcriptase of the human L1 retrotransposon on its own template in vitro.
Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities.
Down-regulation of telomerase activity and activation of caspase-3 are responsible for tanshinone I-induced apoptosis in monocyte leukemia cells in vitro.
Down-regulation of telomerase activity via protein phosphatase 2A activation in salvicine-induced human leukemia HL-60 cell apoptosis.
Downregulation of telomerase activity in HL60 cells by differentiating agents is accompanied by increased expression of telomerase-associated protein.
Downregulation of telomerase activity in human promyelocytic cell line using RNA interference.
Dual coding potential of a 2',5'-branched ribonucleotide in DNA.
Duplex structural differences and not 2'-hydroxyls explain the more stable binding of HIV-reverse transcriptase to RNA-DNA versus DNA-DNA.
Dynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching.
Editing of apolipoprotein B messenger RNA in differentiated Caco-2 cells.
Effect of antisense hTERT mRNA oligodeoxynucleotide on telomerase activity of leukemic cells.
Effect of ATP on the Friend Murine leukemia virus-associated endonuclease activity and the endonuclease activity of the avian myeloblastosis virus RNA-directed DNA polymerase.
Effect of ginseng saponin, arsenic trioxide, beta-elemene combined with CTX on telomere-telomerase system in K562 cell line.
Effect of UV Light on RNA-Directed DNA Polymerase Activity of Murine Oncornaviruses.
Effects of arsenic on telomerase and telomeres in relation to cell proliferation and apoptosis in human keratinocytes and leukemia cells in vitro.
Effects of geldanamycin and its derivatives on RNA-directed DNA polymerase and infectivity of Rauscher leukemia virus.
Effects of Manisa propolis on telomerase activity in leukemia cells obtained from the bone marrow of leukemia patients.
Effects of Poly(1-vinyluracil) and Poly(9-vinyladenine) on viral RNA-directed DNA polymerase.
Effects of streptovaricins and their degradation products on RNA-directed DNA polymerase of Rauscher leukemia virus.
Effects on DNA synthesis and translocation caused by mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptase.
Efficient marking of neural stem cell-derived neurons with a modified murine embryonic stem cell virus, MESV2.
Efficient N-tailing of blunt DNA ends by Moloney murine leukemia virus reverse transcriptase.
Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome.
Enzymatic activity of endogenous telomerase associated with intact nuclei from human leukemia CEM cells.
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase for use in cDNA synthesis.
Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells.
Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells.
Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review).
Erythroid differentiation in cultured Friend leukemia cells treated with metabolic inhibitors.
Escherichia coli DNA polymerase III epsilon subunit increases Moloney murine leukemia virus reverse transcriptase fidelity and accuracy of RT-PCR procedures.
Evaluation of Manisa propolis effect on leukemia cell line by telomerase activity.
Evaluation of telomerase mRNA (hTERT) in childhood acute leukemia.
Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.
Evidence that a downstream pseudoknot is required for translational read-through of the Moloney murine leukemia virus gag stop codon.
Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities.
Expression in Escherichia coli of a Moloney murine leukemia virus reverse transcriptase whose structure closely resembles the viral enzyme.
Expression of moloney murine leukemia virus reverse transcriptase in a cell-free protein expression system.
Expression of Moloney murine leukemia virus RNase H rescues the growth defect of an Escherichia coli mutant.
Expression of the gag-pol fusion protein of Moloney murine leukemia virus without gag protein does not induce virion formation or proteolytic processing.
First Report of Pear blister canker viroid in Pear Trees in Argentina.
First Report of Tomato Brown Rugose Fruit Virus on Tomato in Syria.
Folding the ribonuclease H domain of Moloney murine leukemia virus reverse transcriptase requires metal binding or a short N-terminal extension.
Free energy mapping of class I MHC molecules and structural determination of bound peptides.
Function of PRRSV GP5 envelope protein by using pseudotyped virus.
Functional characterization of adenoviral/retroviral chimeric vectors and their use for efficient screening of retroviral producer cell lines.
Functional replacement of nucleocapsid flanking regions by heterologous counterparts with divergent primary sequences: effects of chimeric nucleocapsid on the retroviral replication cycle.
Further increase in thermostability of Moloney murine leukemia virus reverse transcriptase by mutational combination.
Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants.
Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media.
Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors.
Generation of thermostable Moloney murine leukemia virus reverse transcriptase variants using site saturation mutagenesis library and cell-free protein expression system.
Genetic encoding of DNA nanostructures and their self-assembly in living bacteria.
Genetic events associated with arsenic-induced malignant transformation: applications of cDNA microarray technology.
Genome-wide specificity of prime editors in plants.
Gln(84) of moloney murine leukemia virus reverse transcriptase regulates the incorporation rates of ribonucleotides and deoxyribonucleotides.
Gossypol exerts its cytotoxic effect on HL-60 leukemic cell line via decreasing activity of protein phosphatase 2A and interacting with human telomerase reverse transcriptase activity.
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT.
H5N1 influenza virus-like particles produced by transient expression in mammalian cells induce humoral and cellular immune responses in mice.
Heat-shock protein expression in leukemia.
Hematoporphyrin-sensitized photodynamic inactivation of viral RNA-dependent DNA polymerase.
High susceptibility of c-KIT(+)CD34 (+) precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model.
High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range.
Homoharringtonine-Induced Apoptosis of Human Leukemia HL-60 Cells is Associated with Down-Regulation of Telomerase.
Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templates.
hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup.
Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro.
Human T cell leukemia virus type II increases telomerase activity in uninfected CD34+ hematopoietic progenitor cells.
Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal.
Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells.
Identification of amino acids inserted during suppression of UAA and UGA termination codons at the gag-pol junction of Moloney murine leukemia virus.
Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.
Identification of novel singly spliced pX mRNA transcripts common to all human T-cell leukemia virus type 1-related retroviruses.
Impact of gonadotropin supplementation on the expression of germ cell marker genes (MATER, ZAR1, GDF9, and BMP15) during in vitro maturation of buffalo (Bubalus bubalis) oocyte.
Impaired telomere regulation mechanism by TRF1 (telomere-binding protein), but not TRF2 expression, in acute leukemia cells.
Improvement of Moloney murine leukemia virus reverse transcriptase thermostability by introducing a disulfide bridge in the ribonuclease H region.
In patients with BCR-ABL-positive ALL in CR peripheral blood contains less residual disease than bone marrow: implications for autologous BMT.
In vitro anti-telomerase activity of novel lycopene-loaded nanospheres in the human leukemia cell line K562.
Inactivation of p16INK4a (inhibitor of cyclin-dependent kinase 4A) immortalizes primary human keratinocytes by maintaining cells in the stem cell compartment.
Incorporation of Pr160(gag-pol) into virus particles requires the presence of both the major homology region and adjacent C-terminal capsid sequences within the Gag-Pol polyprotein.
Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases.
Influence of various 2- and 2'-substituted polyadenylic acids on murine leukemia virus reverse transcriptase.
Influence on stability in Escherichia coli of the carboxy-terminal structure of cloned Moloney murine leukemia virus reverse transcriptase.
Inhibition of cyclooxygenase-2 and telomerase activities in human leukemia cells by dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp.
Inhibition of friend murine leukemia virus production by low-ionic-strength medium.
Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs.
Inhibition of human telomerase enhances the effect of the tyrosine kinase inhibitor, imatinib, in BCR-ABL-positive leukemia cells.
Inhibition of Moloney murine leukemia virus reverse transcriptase activity by tetrahydroxyxanthones isolated from the Chinese herb, Tripterospermum lanceolatum (Hyata).
Inhibition of Moloney murine leukemia virus reverse transcriptase by alpha-anomeric oligonucleotides.
Inhibition of Moloney murine leukemia virus reverse transcriptase by partially 5-thiolated polyuridylic acid.
Inhibition of myc promoter and telomerase activity and induction of delayed apoptosis by SYUIQ-5, a novel G-quadruplex interactive agent in leukemia cells.
Inhibition of oncornavirus functions by 2'-azido polynucleotides.
Inhibition of RNA-directed DNA polymerase from Rauscher leukemia virus by the 5'-triphosphate of cytosine arabinoside.
Inhibition of RNase H activity and viral replication by single mutations in the 3' region of Moloney murine leukemia virus reverse transcriptase.
Inhibition of telomerase activity and bcl-2 expression in berbamine-induced apoptosis in HL-60 cells.
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.
Inhibition of telomerase activity correlates with a decrease in the RNA component of telomerase during differentiation.
Inhibitory effects of flavonoids on Moloney murine leukemia virus reverse transcriptase activity.
Integrated evaluation of telomerase activation and telomere maintenance across cancer cell lines.
Integrating retroviral cassette extends gene delivery of HSV-1 expression vectors to dividing cells.
Interchromosomal homology searches drive directional ALT telomere movement and synapsis.
Interferon alpha down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells.
Interleukin-6, -8, and TGF-? Secreted from Mesenchymal Stem Cells Show Functional Role in Reduction of Telomerase Activity of Leukemia Cell Via Wnt5a/?-Catenin and P53 Pathways.
Interphase detection of t(4;14)(p16.3;q32.3) by in situ hybridization and FGFR3 overexpression in plasma cell malignancies.
Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison.
Ionophorous polymers. Interaction with polynucleotides and effects on RNA-directed DNA polymerase activity.
Isolation and characterization of a glucose/mannose-specific lectin with stimulatory effect on nitric oxide production by macrophages from the emperor banana.
Isolation of a recombinant murine leukemia virus utilizing a new primer tRNA.
Isolation of cloned Moloney murine leukemia virus reverse transcriptase lacking ribonuclease H activity.
JAK2 inhibition in JAK2V617F-bearing leukemia cells enriches CD34+ leukemic stem cells that are abolished by the telomerase inhibitor GRN163L.
Kinetic and mutational analysis of human immunodeficiency virus type 1 reverse transcriptase inhibition by inophyllums, a novel class of non-nucleoside inhibitors.
Knockdown of hTERT Alters Biophysical Properties of K562 Cells Resulting in Decreased Migration Rate In Vitro.
Korean red ginseng extract induces apoptosis and decreases telomerase activity in human leukemia cells.
Label-Free Telomerase Activity Detection via Electrochemical Impedance Spectroscopy.
Lack of evidence for the involvement of type-C and type-B retroviruses in radiation leukemogenesis of NFS mice.
Lentin, a novel and potent antifungal protein from shitake mushroom with inhibitory effects on activity of human immunodeficiency virus-1 reverse transcriptase and proliferation of leukemia cells.
Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
Localization of reverse-transcriptase in interferon-treated mouse cells chronically infected with Moloney leukemia virus.
Low efficiency of the Moloney murine leukemia virus reverse transcriptase during reverse transcription of rare t(8;21) fusion gene transcripts.
Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element.
Mechanism of action of Moloney murine leukemia virus RNA-directed DNA polymerase associated RNase H (RNase H I).
Mechanism of Human Telomerase Reverse Transcriptase (hTERT) Regulation and Clinical Impacts in Leukemia.
Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides.
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase.
Mechanistic insights into the roles of three linked single-stranded template binding residues of MMLV reverse transcriptase in misincorporation and mispair extension fidelity of DNA synthesis.
Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: evaluation of PML-RAR alpha and RAR alpha-PML assessment in patients who ultimately relapse.
Model of inhibition of Thermus aquaticus polymerase and Moloney murine leukemia virus reverse transcriptase by tea polyphenols (+)-catechin and (-)-epigallocatechin-3-gallate.
Modulating telomerase activity in tumor patients by targeting dyskerin binding site for hTR.
Modulation of stop codon read-through efficiency and its effect on the replication of murine leukemia virus.
Molecular approaches to the diagnosis and evaluation of lymphoid malignancies.
Molecular characterization of KMT2A fusion partner genes in 13 cases of pediatric leukemia with complex or cryptic karyotypes.
Molecular mimicry between a uveitopathogenic site of S-antigen and viral peptides. Induction of experimental autoimmune uveitis in Lewis rats.
Moloney murine leukemia virus protease expressed in bacteria is enzymatically active.
Mortalization of human promyelocytic leukemia HL-60 cells to be more susceptible to sodium butyrate-induced apoptosis and inhibition of telomerase activity by down-regulation of nucleophosmin/B23.
MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-?B pathway.
Multiple mechanisms of telomere maintenance exist in liposarcomas.
Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.
Multiple Site-Directed and Saturation Mutagenesis by the Patch Cloning Method.
Multistep regulation of telomerase during differentiation of HL60 cells.
Murine leukemia virus protease is encoded by the gag-pol gene and is synthesized through suppression of an amber termination codon.
Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase.
Murine sarcoma virus defectiveness. Viral polymerase expression in murine and nonmurine host cells transformed by S + L - type murine sarcoma virus.
Musa acuminata (Del Monte banana) lectin is a fructose-binding lectin with cytokine-inducing activity.
Mutant of Moloney murine leukemia virus reverse transcriptase exhibits higher resistance to common RT-qPCR inhibitors.
Mutational analysis of the DNA polymerase and ribonuclease H activities of human immunodeficiency virus type 2 reverse transcriptase expressed in Escherichia coli.
Mutational analysis of the gag-pol junction of Moloney murine leukemia virus: requirements for expression of the gag-pol fusion protein.
Mutational analysis of the ribonuclease H activity of human immunodeficiency virus 1 reverse transcriptase.
Mutations of the RNase H C helix of the Moloney murine leukemia virus reverse transcriptase reveal defects in polypurine tract recognition.
Natural UAG suppressor glutamine tRNA is elevated in mouse cells infected with Moloney murine leukemia virus.
Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus.
New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors.
Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer.
Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton's lymphoma ascites tumor.
Nuclease activities of Moloney murine leukemia virus reverse transcriptase. Mutants with altered substrate specificities.
Nucleophosmin/B23 regulates the susceptibility of human leukemia HL-60 cells to sodium butyrate-induced apoptosis and inhibition of telomerase activity.
Nucleotide sequences of gag-pol regions that determine the Fv-1 host range property of BALB/c N-tropic and B-tropic murine leukemia viruses.
Omacetaxine mepesuccinate induces apoptosis and cell cycle arrest, promotes cell differentiation, and reduces telomerase activity in diffuse large B?cell lymphoma cells.
Oncornaviral protein modulation in mouse uterine tissue by estrogen (38467).
Overexpression of MiR-138 Inhibits Cell Growth and Induces Caspase-mediated Apoptosis in Acute Promyelocytic Leukemia Cell Line.
Paired multiplex reverse-transcriptase polymerase chain reaction (PMRT-PCR) analysis as a rapid and accurate diagnostic tool for the detection of MLL fusion genes in hematologic malignancies.
Patensin-induced apoptosis is accompanied by decreased bcl-2 expression and telomerase activity in HL-60 cells.
Pectenotoxin-2 represses telomerase activity in human leukemia cells through suppression of hTERT gene expression and Akt-dependent hTERT phosphorylation.
Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment.
Phaseococcin, an antifungal protein with antiproliferative and anti-HIV-1 reverse transcriptase activities from small scarlet runner beans.
Photoaffinity labeling of the primer binding domain in murine leukemia virus reverse transcriptase.
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells.
PML is required for telomere stability in non-neoplastic human cells.
PML-IV functions as a negative regulator of telomerase by interacting with TERT.
Podoscyphic acid, a new inhibitor of avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptase from a Podoscypha species.
Polymerase chain reaction amplification fails to detect aromatase cytochrome P450 transcripts in normal human endometrium or decidua.
Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and Moloney murine leukemia viruses are functionally uncoupled.
Polypurine tract primer generation and utilization by Moloney murine leukemia virus reverse transcriptase.
Poor prognosis acute myelogenous leukemia: 3--biological and molecular biological changes during remission induction therapy.
Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate.
Preparation and characterization of the RNase H domain of Moloney murine leukemia virus reverse transcriptase.
Preparation of RNA-directed DNA polymerase from spleens of Balb-c mice infected with Rauscher leukemia virus.
Proceedings: Inhibition of mouse leukemia virus RNA-dependent DNA polymerase by 2'-OH-substituted polynucleotides.
Properties of strand displacement synthesis by Moloney murine leukemia virus reverse transcriptase: mechanistic implications.
Purification and Characterization of a Laccase with Inhibitory Activity toward HIV-1 Reverse Transcriptase and Tumor Cells from an Edible Mushroom (Pleurotus cornucopiae).
Purification and properties of Rauscher leukemia virus DNA polymerase and selective inhibition of mammalian viral reverse transcriptase by inorganic phosphate.
Purification of a trypsin-stable lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activity.
Purification of M-MLVH- RT on a 9-aminoethyladenine-(1,6-diamine-hexane)-triazine selected from a combinatorial library of dNTP-mimetic ligands.
Purification of RNA-directed DNA polymerase from mouse spleen infected with Rauscher leukemia virus.
Purification of RNA-directed DNA polymerase from spleens of BALB/C mice infected with Rauscher leukemia virus [proceedings]
Pushing the limits: defeating leukemia stem cells by depleting telomerase.
Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes.
Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide.
Recombination during reverse transcription: an evaluation of the role of the nucleocapsid protein.
Reconstitution in vitro of RNase H activity by using purified N-terminal and C-terminal domains of human immunodeficiency virus type 1 reverse transcriptase.
Reduction of transforming growth factor-?1 expression in leukemia its possible role in leukemia development.
Regulation of an H-ras-related transcript by parathyroid hormone in rat osteosarcoma cells.
Regulation of telomerase activity in camptothecin-induced apoptosis of human leukemia HL-60 cells.
Relationship between B-Cell-specific moloney murine leukemia virus integration site 1 (BMI-1) and homologous recombination regulatory genes in invasive ductal breast carcinomas.
Replacement of murine leukemia virus readthrough mechanism by human immunodeficiency virus frameshift allows synthesis of viral proteins and virus replication.
Resolution and characterization of intracytoplasmic forms of reverse transcriptase from Rauscher leukemia virus-producing cells.
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation.
Retroviral reverse transcriptase inhibitory activity in Thai herbs and spices: screening with Moloney murine leukemia viral enzyme.
Reverse Transcriptase (EC 2.7.7.49) : The Use of Cloned Maloney Murine Leukemia Virus Reverse Transcriptase to Synthesize DNA from RNA.
Reverse transcriptase of Moloney murine leukemia virus binds to eukaryotic release factor 1 to modulate suppression of translational termination.
Reverse transcriptase. The use of cloned Moloney murine leukemia virus reverse transcriptase to synthesize DNA from RNA.
Reverse transcription of a naturally occurring nonretroviral RNA produces a precise deletion in the majority of its cDNA products.
Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells.
Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.
Ribosomal frameshifting at the Gag-Pol junction in avian leukemia sarcoma virus forms a novel cleavage site.
Ribosomal protein S15 from Escherichia coli modulates its own translation by trapping the ribosome on the mRNA initiation loading site.
RNA degradation and primer selection by Moloney murine leukemia virus reverse transcriptase contribute to the accuracy of plus strand initiation.
RNA expression of cardiac troponin T isoforms in diseased human skeletal muscle.
RNA-dependent DNA polymerase activity in ocular granulocytic sarcoma associated to acute myelomonocytic leukemia in Turkish children. Biochemical and immunological characterization of the enzyme.
RNA-directed DNA polymerase and virus-induced leukemia in mice.
RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-template.
RNase H domain of Moloney murine leukemia virus reverse transcriptase retains activity but requires the polymerase domain for specificity.
Role of divalent ion complex formation in pyran--inhibition of nucleic acid biosynthesis.
Role of Ets/Id proteins for telomerase regulation in human cancer cells.
Role of human telomerase reverse transcriptase and telomeric-repeat binding factor proteins 1 and 2 in human hematopoietic cells.
Role of neuropilin-1 and its expression in Egyptian acute myeloid and acute lymphoid leukemia patients.
Rt-PCR method for diagnosis and follow-up of hematological malignancies: first approach in Bangladesh.
Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges.
Screening and Evaluation of Novel Compounds against Hepatitis B Virus Polymerase Using Highly Purified Reverse Transcriptase Domain.
Secondary structure in the 3' UTR of EGF and the choice of reverse transcriptases affect the detection of message diversity by RT-PCR.
Selection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity.
Selective cytotoxicity and telomere damage in leukemia cells using the telomerase inhibitor BIBR1532.
Selective inactivation of M-MuLV RT RNase H activity by site-directed PEGylation: an improved ability to synthesize long cDNA molecules.
Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines.
Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines.
Separation of cellular and viral DNA polymerases by affinity chromatography on polynucleotide-Sepharose.
Silencing of CHD5 gene by promoter methylation in leukemia.
Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.
Simultaneous purification of RNA-dependent DNA polymerase and gs-antigen from Rauscher leukemia virus.
Site-directed mutagenesis of Moloney murine leukemia virus reverse transcriptase. Demonstration of lysine 103 in the nucleotide binding site.
Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration properties.
Stabilization of human immunodeficiency virus type 1 reverse transcriptase by site-directed mutagenesis
Stabilization of human immunodeficiency virus type 1 reverse transcriptase by site-directed mutagenesis.
Stabilization of Moloney murine leukemia virus reverse transcriptase by site-directed mutagenesis of surface residue Val433.
Stem cell marker expression in human trisomy 21 amniotic fluid cells and trophoblasts.
Strand displacement synthesis capability of Moloney murine leukemia virus reverse transcriptase.
Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase.
Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase.
Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus.
Structural studies of the RNA pseudoknot required for readthrough of the gag-termination codon of murine leukemia virus.
Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.
Structure of glycosylated and unglycosylated gag and gag-pol precursor proteins of Moloney murine leukemia virus.
Structure-based moloney murine leukemia virus reverse transcriptase mutants with altered intracellular direct-repeat deletion frequencies.
Studies on the inhibition of Moloney murine leukemia virus reverse transcriptase by N-tritylamino acids and N-tritylamino acid-nucleotide compounds.
Study of MMLV RT- binding with DNA using surface plasmon resonance biosensor.
Substitution of Asp114 or Arg116 in the fingers domain of moloney murine leukemia virus reverse transcriptase affects interactions with the template-primer resulting in decreased processivity.
Suppression of telomerase activity and cytokine messenger RNA levels in acute myelogenous leukemia cells in vivo in patients by amifostine and interleukin 4.
Suramin: a potent inhibitor of the reverse transcriptase of RNA tumor viruses.
Susceptibility of human T cell leukemia virus type 1 to reverse-transcriptase inhibitors: evidence for resistance to lamivudine.
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
Suspension packaging cell lines for the simplified generation of T-cell receptor encoding retrovirus vector particles.
Synergistic down-regulation of telomerase activity and hTERT mRNA expression by combination of retinoic acid and GM-CSF in human myeloblastic leukemia ML-1 cells.
Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts.
Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity.
Targeting of multiple senescence-promoting genes and signaling pathways by triptonide induces complete senescence of acute myeloid leukemia cells.
Targeting telomerase in hematologic malignancy.
Telomerase activity and expression and telomere analysis in situ in the course of treatment of childhood leukemias.
Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-ex vivo culture.
Telomerase activity and telomere length in acute leukemia: correlations with disease progression, subtypes and overall survival.
Telomerase activity and telomere length in patients with acute promyelocytic leukemia: indicative of proliferative activity, disease progression, and overall survival.
Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy.
Telomerase activity in human leukemic cells with or without monosomy 7 or 7q-.
Telomerase activity in normal and malignant hematopoietic cells.
Telomerase activity in peripheral blood mononuclear cells after whole body irradiation.
Telomerase activity in vivo in human malignant hematopoietic cells.
Telomerase and the benign and malignant megakaryoblastic leukemias of Down syndrome.
Telomerase from human leukemia cells: properties and its interaction with deoxynucleoside analogues.
Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation.
Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.
Telomerase inhibition enhances apoptosis in human acute leukemia cells: possibility of antitelomerase therapy.
Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.
Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia.
Telomerase is limiting the growth of acute myeloid leukemia cells.
Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
Telomerase reactivation in leukemia cells.
Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells.
Telomerase regulation in hematological cancers: A matter of stemness?
Telomerase. A target for anticancer therapy.
Telomere biology of pediatric cancer.
Telomere dynamics in childhood leukemia and solid tumors: a follow-up study.
Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging.
Telomere dysfunction and telomerase reactivation in human leukemia cell lines after telomerase inhibition by the expression of a dominant-negative hTERT mutant.
Telomere length and telomerase activity: variations with advancing age and potential role in childhood malignancies.
Telomeres and telomerase in hematologic neoplasia.
Telomeres and telomerase in human leukemias.
Telomeres in health and disease.
Template activity of poly(2'-fluoro-2'-deoxyinosinic acid) for murine leukemia virus reverse transcriptase.
Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro.
The ability of a variety of polymerases to synthesize past site-specific cis-syn, trans-syn-II, (6-4), and Dewar photoproducts of thymidylyl-(3'-->5')-thymidine.
The basic loop of the RNase H domain of MLV RT is important both for RNase H and for polymerase activity.
The co-expression of telomerase and ALT pathway in human breast cancer tissues.
The correlation of telomerase and IL-10 with leukemia transformation in a mouse model of chronic lymphocytic leukemia (CLL).
The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression.
The effect of silymarin on telomerase activity in the human leukemia cell line K562.
The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype.
The expression of telomeric proteins and their probable regulation of telomerase during the differentiation of all-trans-retinoic acid-responsive and -resistant acute promyelocytic leukemia cells.
The interaction of illimaquinone, a selective inhibitor of the RNase H activity, with the reverse transcriptases of human immunodeficiency and murine leukemia retroviruses.
The Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells.
The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase.
The R-U5-5' leader sequence of neurovirulent wild mouse retrovirus contains an element controlling the incubation period of neurodegenerative disease.
The role of Moloney murine leukemia virus RNase H activity in the formation of plus-strand primers.
The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
The virion-associated Gag-Pol is decreased in chimeric Moloney murine leukemia viruses in which the readthrough region is replaced by the frameshift region of the human immunodeficiency virus type 1.
Therapeutic implications of leukemic stem cell pathways.
Threshold number of provirus copies required per cell for efficient virus production and interference in moloney murine leukemia virus-infected NIH 3T3 cells.
Tianshengyuan-1 (TSY-1) regulates cellular Telomerase activity by methylation of TERT promoter.
Transduction of Schistosoma japonicum schistosomules with vesicular stomatitis virus glycoprotein pseudotyped murine leukemia retrovirus and expression of reporter human telomerase reverse transcriptase in the transgenic schistosomes.
Transgene amplification and persistence after delivery of retroviral vector and packaging functions with E1/E4-deleted adenoviruses.
Translational readthrough of the murine leukemia virus gag gene amber codon does not require virus-induced alteration of tRNA.
Trifluoperazine and its metal complexes inhibit the Moloney leukemia virus reverse transcriptase.
Tryptic peptide analysis of gag and gag-pol gene products of Rauscher murine leukemia virus.
Two novel real-time reverse transcriptase PCR assays for rapid detection of bacterial contamination in platelet concentrates.
Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs.
Valine of the YVDD motif of moloney murine leukemia virus reverse transcriptase: role in the fidelity of DNA synthesis.
Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes.
Viral reverse transcriptase suppression associated with erythroid differentiation of Friend leukemia cells.
Viral RNA in middle ear mucosa and exudates in patients with chronic otitis media with effusion.
VSV-G envelope glycoprotein forms complexes with plasmid DNA and MLV retrovirus-like particles in cell-free conditions and enhances DNA transfection.
Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells.
WT1 contributes to leukemogenesis: expression patterns in 7,12-dimethylbenz[a]anthracene (DMBA)-induced leukemia.
YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro.
[A quantitative assay for telomerase activity in peripheral blood mononuclear cells from patients with acute leukemia]
[Alteration of activities of telomerase in tanshinone IIA inducing apoptosis of the leukemia cells]
[Analysis for telomerase activity in various hematologic disorders]
[Analysis of molecular mechanism involved in development of acute myeloid leukemia].
[Antisense hTERT inhibits gene expression and functional activity of telomerase in leukemia cell lines.]
[Antisense human telomerase reverse transcriptase inhibits leukemia cell proliferation in vitro]
[Construction of a cDNA library from liver tissue of rhesus monkey, Macaca mulatta]
[DNA topoisomerase and telomerase activity with relation to multi-drug resistance in leukemia--review]
[Effect of human telomerase reverse transcriptase gene antisense oligodeoxynucleotide on telomerase activity in leukemia cells]
[Effects of arsenic trioxide, ginseng saponin and beta-elemene on telomere-telomerase system in K562 cell line]
[Effects of AZT on leukemia cell line KG-1a proliferation and telomerase activity].
[Effects of Sodium Nitroprusside on P38MAPK/STAT3 Activation and Telomerase Reverse Transcriptase mRNA Expression in Inducing Apoptosis of K562 Cell Line.]
[Expression level of TRF1 protein in human acute leukemia and its relationship with activity of telomerase]
[Expression of human telomere repeat binding factor 1 (TRF1) in acute leukemia cells and its correlation with telomerase activities]
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
[Expression of telomerase in acute leukemia]
[Expressions of B-cell-specific monoclonal leukemia virus insert site 1 and human telomerase reverse transcriptase genes in CD34+ cells during ex vivo expansion process].
[Immunologic aspects of preparation of antiserum to the reverse transcriptase from avian myeloblastosis virus]
[Inhibiting effect of arsenic trioxide on telomerase activity of NB4 and Jurkat cell lines]
[Inhibition Effect of Diimide G-quadruplex Ligand on Proliferation of Leukemia Cells and Its Molecular Mechanisms.]
[Localization of RNA-dependent DNA polymerase in rat thymus cells infected with moloney leukemia virus]
[Molecular diagnosis for diagnosis of leukemia]
[Plasmid-Mediated RNAi Targeting hTERT Inhibits Telomerase Activity in K562 Cell Line.]
[Preliminary analysis on human telomerase reverse transcriptase gene expression in acute leukemia]
[Prokaryotic expression and purification of moloney murine leukemia virus reverse transcriptase and verification of the activity]
[Regulation of telomerase activity in HL-60 and NB4 cells by arsenic trioxide]
[Relationship among telomerase activity, expression of human telomerase reverse transcriptase (hTERT), and expression of c-myc in acute leukemia]
[Studies of hTERT gene expression in acute leukemia children]
[Study of telomerase activity and its related genes expression in leukemia cells]
[Study of Telomerase Activity in Bone Marrow Cells from Patients with Myelodysplastic Syndromes]
[Telomerase Activity Expressed in Acute Leukemia Cell]
[Telomerase downregulation during differentiation of leukemia cells]
[Telomerase, cell immortality and cancer]
[Telomere and telomerase]
[Telomeres and telomerase in leukemias]
[The Effect and Mechanism of Novel Telomerase Inhibitor Nilo 22 on Leukemia Cells].
[The expression of human telomerase reverse transcriptase mRNA and its significance in acute leukemia]
[The relationship between telomerase activity and cell cyele in acute leukemia cells]
[To inhibit ERK for enhancing chemotherapy sensitivity of drug-resistance cell lines of leukemia and ovarian carcinoma]
Leukemia L1210
A low-molecular mass ribonuclease from the brown oyster mushroom.
Leukemia, B-Cell
CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia.
Cytotoxic effects of caffeic acid undecyl ester are involved in the inhibition of telomerase activity in NALM-6 human B-cell leukemia cells.
Evaluation of telomerase activity in patients with chronic B lymphocytic leukemia versus age matched controls. Correlation between telomerase activity and bone marrow infiltration.
Leukemia, Erythroblastic, Acute
Knockdown of hTERT Alters Biophysical Properties of K562 Cells Resulting in Decreased Migration Rate In Vitro.
The over-expression of aquaporin-1 alters erythroid gene expression in human erythroleukemia K562 cells.
Viral reverse transcriptase suppression associated with erythroid differentiation of Friend leukemia cells.
Leukemia, Feline
Inhibition of oncornavirus functions by 2'-azido polynucleotides.
Molecular analysis of several classes of endogenous feline leukemia virus elements.
Mutational analysis of the gag-pol junction of Moloney murine leukemia virus: requirements for expression of the gag-pol fusion protein.
Nucleotide sequence of the gag gene and gag-pol junction of feline leukemia virus.
Leukemia, Lymphocytic, Chronic, B-Cell
CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia.
Cytokine gene expression in B-cell chronic lymphocytic leukemia: evidence of constitutive interleukin-8 (IL-8) mRNA expression and secretion of biologically active IL-8 protein.
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Evaluation of telomerase activity in patients with chronic B lymphocytic leukemia versus age matched controls. Correlation between telomerase activity and bone marrow infiltration.
Purification of RNA-instructed DNA polymerase from human leukemic spleens.
Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia.
Role of miR-15a/miR-16-1 and the TP53 axis in regulating telomerase expression in chronic lymphocytic leukemia.
T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients.
Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells.
Telomerase activity is not a prognostic factor in chronic lymphocytic leukemia.
Telomerase expression in B-cell chronic lymphocytic leukemia predicts survival and delineates subgroups of patients with the same igVH mutation status and different outcome.
Telomere dysfunction and hematologic disorders.
Telomere length and expression of human telomerase reverse transcriptase splice variants in chronic lymphocytic leukemia.
Telomere length and telomerase activity predict survival in patients with B cell chronic lymphocytic leukemia.
Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes.
The correlation of telomerase and IL-10 with leukemia transformation in a mouse model of chronic lymphocytic leukemia (CLL).
[Telomere length and telomerase expression activity in mononuclear cells of patients with chronic lymphocytic leukemia]
Leukemia, Lymphoid
Over-expression of the functional interleukin-11 alpha receptor in the development of B-cell chronic lymphocytic leukemia.
Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia.
Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells.
Chemistry and biochemistry of 2',5'-oligoadenylate-based antisense strategy.
Combined RT-PCR and metaphase-FISH posttransplant studies in pediatric patients with chronic myeloid leukemia.
Detection of molecular variants of BCR-ABL gene in bone marrow and blood of patients with chronic myeloid leukemia by reverse-transcriptase polymerase chain reaction (RT-PCR).
Erratum to: Expression pattern of hTERT telomerase subunit gene in different stages of chronic myeloid leukemia.
Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice.
Expression pattern of hTERT telomerase subunit gene in different stages of chronic myeloid leukemia.
Functional genomics of hTERT gene in leukemic myelopoiesis.
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells.
Increased telomerase activity is associated with shorter survival in patients with chronic phase chronic myeloid leukemia.
Inhibition of human telomerase enhances the effect of the tyrosine kinase inhibitor, imatinib, in BCR-ABL-positive leukemia cells.
Interleukin-6, -8, and TGF-? Secreted from Mesenchymal Stem Cells Show Functional Role in Reduction of Telomerase Activity of Leukemia Cell Via Wnt5a/?-Catenin and P53 Pathways.
Is telomerase a player in chronic phase chronic myeloid leukemia, disease progression and imatinib resistance?
Presence of alternative lengthening of telomeres associated circular extrachromosome telomere repeats in primary leukemia cells of chronic myeloid leukemia.
Quercetin-induced apoptosis involves increased hTERT enzyme activity of leukemic cells.
Real-time quantitative RT-PCR for human telomere elongation reverse transcriptase in chronic myeloid leukemia.
Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression.
Telomerase activity in myelodysplastic syndromes.
Telomerase activity in patients with chronic myeloid leukemia and lymphoma.
Telomerase: obviously activated in the accelerated phase of chronic myeloid leukemia.
[Antisense oligodeoxynucleotide of telomerase gene enhances cisplatin-induced apoptosis in acute myeloid leukemia and chronic myeloid leukemia cells]
[Change of telomerase activity in bone marrow cells from chronic myeloid leukemia patients in different phases]
[Effect of human telomerase reverse transcriptase gene antisense oligodeoxynucleotide on telomerase activity in leukemia cells]
[Real-time reverse-transcriptase polymerase chain reaction in monitoring BCR/ABL transcript levels in chronic myeloid leukemia patients after allogeneic hematopoietic stem cells transplantation]
Leukemia, Myeloid
A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias.
Analysis of synthetic RNA-directed DNA polymerase activities in the spleen of a rat with myelogenous leukemia induced by N-nitroso-N-butylurea.
Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma, and glioma cells in culture.
Down-regulation of four arsenic antagonists on apoptosis and telomerase activity induced by arsenic trioxide in three myelocytic leukemia cell lines.
Induced apoptosis by mild hyperthermia occurs via telomerase inhibition on the three human myeloid leukemia cell lines: TF-1, K562, and HL-60.
Inhibition of telomerase activity with hTERT antisense increases the effect of CDDP-induced apoptosis in myeloid leukemia.
Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis.
Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL.
[Study on the expression of tankyrase in malignant hematopoietic cells and its relation with telomerase activity]
Leukemia, Myeloid, Acute
A spectrum of severe familial liver disorders associate with telomerase mutations.
Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase.
APRIL gene expression in a cohort of Egyptian acute myeloid leukemia patients: Clinical and prognostic significance.
Association between TERT gene polymorphisms and acute myeloid leukemia susceptibility in a Chinese population: a case-control study.
Biological and clinical implications of telomere dysfunction in myeloid malignancies.
Clinical implications of telomerase activity levels in acute leukemia.
Clinical significance of telomerase genes (hTERC and hTERT) amplification in patients with acute myeloid leukemia.
Competitive CBFbeta/MYH11 reverse-transcriptase polymerase chain reaction for quantitative assessment of minimal residual disease during postremission therapy in acute myeloid leukemia with inversion(16): a pilot study.
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia.
Correction to: MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.
Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia.
Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.
Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells.
Fanconi Anemia germline variants as susceptibility factors in aplastic anemia, MDS and AML.
Heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor expression by acute myeloid leukemia cells.
Human telomerase reverse transcriptase expression in a CD34-positive hematopoietic progenitor of myelodysplastic syndrome and acute myelogenous leukemia.
Immune responses and long-term disease recurrence status after telomerase-based dendritic cell immunotherapy in patients with acute myeloid leukemia.
Lack of correlation between telomere length and telomerase activity and expression in leukemic cells.
Molecular cytogenetics and multiplex reverse-transcriptase polymerase chain reaction for risk stratification in acute myeloid leukemia.
Multistep regulation of telomerase during differentiation of HL60 cells.
MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia.
RETRACTED: Heterogeneous promoter activity of the telomerase reverse transcriptase gene in individual acute myeloid leukemia cells defined by lentiviral reporter assay.
Retraction. Heterogeneous promoter activity of the telomerase reverse transcriptase gene in individual acute myeloid leukemia cells defined by lentiviral reporter assay.
Role of neuropilin-1 and its expression in Egyptian acute myeloid and acute lymphoid leukemia patients.
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies.
Suppression of telomerase activity and cytokine messenger RNA levels in acute myelogenous leukemia cells in vivo in patients by amifostine and interleukin 4.
Telomerase activity in human acute myelogenous leukemia: inhibition of telomerase activity by differentiation-inducing agents.
Telomerase activity in myelodysplastic syndromes.
Telomerase activity in normal leukocytes and in hematologic malignancies.
Telomerase activity in preleukemia and acute myelogenous leukemia.
Telomerase activity is prognostic in pediatric patients with acute myeloid leukemia: comparison with adult acute myeloid leukemia.
Telomerase from human leukemia cells: properties and its interaction with deoxynucleoside analogues.
Telomerase gene mutation screening and telomere overhang detection in Chinese patients with acute myeloid leukemia.
Telomerase in Acute Myeloid Leukemia: A Molecular Update on Diagnosis, Prognosis, and Treatment.
Telomerase in hematologic malignancies.
Telomerase is limiting the growth of acute myeloid leukemia cells.
Telomerase reverse transcriptase (TERT) A1062T mutation as a prognostic factor in Egyptian patients with acute myeloid leukemia (AML).
Telomere dysfunction and hematologic disorders.
Telomere length and telomerase complex mutations in pediatric acute myeloid leukemia.
The hypomorphic TERT A1062T variant is associated with increased treatment-related toxicity in acute myeloid leukemia.
[Analysis of molecular mechanism involved in development of acute myeloid leukemia].
[Analysis of telomerase activity and telomere length in acute myelogenous leukemia]
[Antisense oligodeoxynucleotide of telomerase gene enhances cisplatin-induced apoptosis in acute myeloid leukemia and chronic myeloid leukemia cells]
[Effect of human telomerase reverse transcriptase gene antisense oligodeoxynucleotide on telomerase activity in leukemia cells]
[Effects of AZT on leukemia cell line KG-1a proliferation and telomerase activity].
[Expression of human telomere repeat binding factor 1 (TRF1) in acute leukemia cells and its correlation with telomerase activities]
[Expression of telomerase in acute leukemia]
Leukemia, Myelomonocytic, Acute
RNA-dependent DNA polymerase activity in ocular granulocytic sarcoma associated to acute myelomonocytic leukemia in Turkish children. Biochemical and immunological characterization of the enzyme.
Leukemia, Plasma Cell
Interphase detection of t(4;14)(p16.3;q32.3) by in situ hybridization and FGFR3 overexpression in plasma cell malignancies.
Leukemia, Prolymphocytic, T-Cell
Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia.
Leukemia, Promyelocytic, Acute
A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation.
Analysis of telomerase activity and RNA expression in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid.
Contributory role of microRNAs in anti-cancer effects of small molecule inhibitor of telomerase (BIBR1532) on acute promyelocytic leukemia cell line.
Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.
Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells.
Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: evaluation of PML-RAR alpha and RAR alpha-PML assessment in patients who ultimately relapse.
MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-?B pathway.
Overexpression of MiR-138 Inhibits Cell Growth and Induces Caspase-mediated Apoptosis in Acute Promyelocytic Leukemia Cell Line.
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation.
Telomerase activity and telomere length in patients with acute promyelocytic leukemia: indicative of proliferative activity, disease progression, and overall survival.
Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells.
The expression of telomeric proteins and their probable regulation of telomerase during the differentiation of all-trans-retinoic acid-responsive and -resistant acute promyelocytic leukemia cells.
Leukemia, T-Cell
Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition.
Free energy mapping of class I MHC molecules and structural determination of bound peptides.
Human T cell leukemia virus type II increases telomerase activity in uninfected CD34+ hematopoietic progenitor cells.
Human T-cell leukemia virus type II Rex binding and activity require an intact splice donor site and a specific RNA secondary structure.
Identification of novel singly spliced pX mRNA transcripts common to all human T-cell leukemia virus type 1-related retroviruses.
Label-Free Telomerase Activity Detection via Electrochemical Impedance Spectroscopy.
Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.
Protein kinase inhibitor H-7 blocks accumulation of unspliced mRNA of human T-cell leukemia virus type I (HTLV-I).
Regulation of telomerase and telomeres: human tumor viruses take control.
Role of human T-cell leukemia virus type I Tax in expression of the human telomerase reverse transcriptase (hTERT) gene in human T-cells.
Susceptibility of human T cell leukemia virus type 1 to reverse-transcriptase inhibitors: evidence for resistance to lamivudine.
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
Telomerase: a crucial player in HTLV-I-induced human T-cell leukemia.
Telomere attrition induces a DNA double-strand break damage signal that reactivates p53 transcription in HTLV-I leukemic cells.
The Rex proteins of human T-cell leukemia virus type II differ by serine phosphorylation.
Thermodynamic stability and statistical significance of potential stem-loop structures situated at the frameshift sites of retroviruses.
[Study on the expression of tankyrase in malignant hematopoietic cells and its relation with telomerase activity]
Leukemia-Lymphoma, Adult T-Cell
Correlation of telomerase activity with development and progression of adult T-cell leukemia.
Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.
HTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.
Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.
Pathogenesis and treatment of human T-cell leukemia virus infection.
Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.
Serological survey and virus isolation of simian T-cell leukemia/T-lymphotropic virus type I (STLV-I) in non-human primates in their native countries.
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells.
Leukoencephalopathies
Changing patterns in the neuropathogenesis of HIV during the HAART era.
Leukoencephalopathy, Progressive Multifocal
Changing patterns in the neuropathogenesis of HIV during the HAART era.
Leukopenia
Clinical outcomes of lung transplant recipients with telomerase mutations.
Leukoplakia
A case of laryngeal carcinoma in a young adult with dyskeratosis congenita.
Diffuse Mesangial Sclerosis in a Child With Dyskeratosis Congenita Leading to End-stage Renal Disease.
Dyskeratosis congenita and squamous cell carcinoma of the mandibular alveolar ridge.
Immunohistochemical detection of human telomerase reverse transcriptase in oral cancer and pre-cancer.
Prognostic Implications of DNA Repair, Ploidy and Telomerase in the Malignant Transformation Risk Assessment of Leukoplakia.
Telomerase activity in oral and maxillofacial tumors.
Telomerase activity in oral cancer.
[Telomerase activity in oral squamous cell carcinoma and leukoplakia]
Leukoplakia, Oral
Correlation of telomerase activity, clinical prognosis and therapy in oral carcinogenesis.
Telomerase activity in oral and maxillofacial tumors.
Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma.
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Li-Fraumeni Syndrome
Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts.
Telomerase protects cancer-prone human cells from chromosomal instability and spontaneous immortalization.
Lichen Planus
Telomerase activity in oral lichen planus.
Telomerase components as a diagnostic tool in human oral lesions.
Lichen Planus, Oral
hTR RNA Component as a Marker of Cellular Proliferation in Oral Lichen Planus.
Telomerase activity detected in oral lichen planus by RNA in situ hybridisation: not a marker for malignant transformation.
Telomerase activity in oral lichen planus.
Lipodystrophy
A case of lactic acidosis caused by stavudine in an AIDS patient.
A Reduction Grade of Lipodystrophy and Limited Side Effects after HAART Regimen with Raltegravir, Lamivudine, Darunavir and Ritonavir in an HIV-1 Infected Patient after Six Years of Antiretroviral Therapy.
Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs.
Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations.
Assessment of the safety and efficacy of poly-L-lactic acid for the treatment of HIV-associated facial lipoatrophy.
Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy.
Cutaneous effects of highly active antiretroviral therapy in HIV-infected patients.
Cutaneous toxicities of antiretroviral therapy for HIV: part I. Lipodystrophy syndrome, nucleoside reverse transcriptase inhibitors, and protease inhibitors.
Different origin of adipogenic stem cells influences the response to antiretroviral drugs.
Efavirenz-induced gynecomastia in a prepubertal girl with human immunodeficiency virus infection: a case report.
Effects of antiretroviral drug combinations on the differentiation of adipocytes.
Evaluation and management of dyslipidemia in patients with HIV infection.
Evaluation of the risk factors associated with lipodystrophy development in a cohort of HIV-positive patients.
Exploring the pathophysiology behind the more common genetic and acquired lipodystrophies.
Factors related to lipodystrophy and metabolic alterations in patients with human immunodeficiency virus infection receiving highly active antiretroviral therapy.
HIV lipodystrophy: prevalence, severity and correlates of risk in Australia.
HIV-associated lipodystrophy syndrome: A review of clinical aspects.
Impact of switching from human immunodeficiency virus type 1 protease inhibitors to efavirenz in successfully treated adults with lipodystrophy.
Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes.
Lipodystrophy and long-term therapy with nucleoside reverse transcriptase inhibitors.
Lipodystrophy associated with highly active anti-retroviral therapy for HIV infection: the adipocyte as a target of anti-retroviral-induced mitochondrial toxicity.
Long-term complications of nucleoside reverse transcriptase inhibitor therapy.
Longitudinal evaluation and risk factors of lipodystrophy and associated metabolic changes in HIV-infected children.
Mitochondria and HIV infection: the first decade.
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?
Mitochondrial damage in adipose tissue of untreated HIV-infected patients.
Mitochondrial DNA levels in fat and blood cells from patients with lipodystrophy or peripheral neuropathy and the effect of 90 days of high-dose coenzyme Q treatment: a randomized, double-blind, placebo-controlled pilot study.
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy.
Nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity as an etiology for lipodystrophy.
Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study.
The role of nucleoside reverse transcriptase inhibitors in the fat redistribution syndrome.
[Side effects of antiretroviral therapy]
Lipoma
Primary retroperitoneal lipoma: a soft tissue pathology heresy?: report of a case with classic histologic, cytogenetics, and molecular genetic features.
Lipomatosis
Antiretroviral therapy: effects on orofacial health and health care.
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy.
Lipomatosis, Multiple Symmetrical
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy.
Liposarcoma
A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.
Different mRNA expression profile during tumor progression in a well-differentiated liposarcoma--A microdissection approach.
Elevated telomerase activity, c-MYC-, and hTERT mRNA expression: association with tumour progression in malignant lipomatous tumours.
Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-associated PML bodies.
High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma.
High telomerase activity and high HTRT mRNA expression differentiate pure myxoid and myxoid/round-cell liposarcomas.
Multiple mechanisms of telomere maintenance exist in liposarcomas.
On telomere shortening in soft-tissue tumors.
Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles.
Telomeric lengths and telomerase activity in liposarcomas.
[Telomere lengths and telomerase activity in liposarcomas]
Liposarcoma, Myxoid
Analysis of human telomerase reverse transcriptase mRNA (hTERT) expression in myxoid liposarcomas using LightCycler real-time quantitative reverse transcriptase-polymerase chain reaction.
High telomerase activity and high HTRT mRNA expression differentiate pure myxoid and myxoid/round-cell liposarcomas.
Myxoid liposarcoma with transition to round-cell lesion-cell cycle regulator genes and telomerase activity characterizing tumor progression: a case report.
Liver Cirrhosis
Advantages of assaying telomerase activity in ascites for diagnosis of digestive tract malignancies.
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection.
Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma.
Expression of telomerase activity and oxidative stress in human hepatocellular carcinoma with cirrhosis.
Immuno-histochemical detection of human telomerase reverse transcriptase in human liver tissues.
Quantitative analysis and in situ localization of human telomerase RNA in chronic liver disease and hepatocellular carcinoma.
Relationship Between Serum microRNA155 and Telomerase Expression in Hepatocellular Carcinoma.
Relationship between Telomere Maintenance and Liver Disease.
Risk of liver decompensation with cumulative use of mitochondrial toxic nucleoside analogues in HIV/hepatitis C virus coinfection.
Senescence and immortality in hepatocellular carcinoma.
Short telomeres are a risk factor for idiopathic pulmonary fibrosis.
Telomerase and idiopathic pulmonary fibrosis.
Telomerase as a tool for the differential diagnosis of human hepatocellular carcinoma.
Telomeres and Telomerase in the Development of Liver Cancer.
Telomeres and telomerase: new targets for the treatment of liver cirrhosis and hepatocellular carcinoma.
Telomeres, NAFLD and Chronic Liver Disease.
Transforming growth factor-?1 regulates the telomerase reverse transcriptase in rat hepatic stellate cells.
Understanding telomere diseases through analysis of patient-derived iPS cells.
[Expressions of h-TERT, c-myc, PCNA and cell apoptosis in liver carcinogenesis]
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
Liver Cirrhosis, Biliary
T-cell receptor Vbeta gene utilization in primary biliary cirrhosis.
Liver Cirrhosis, Experimental
Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery.
Liver Diseases
A spectrum of severe familial liver disorders associate with telomerase mutations.
Abnormal expression of hepatomas and circulating telomerase and its clinical values.
Activated carbon N-acetylcysteine microcapsule protects against nonalcoholic fatty liver disease in young rats via activating telomerase and inhibiting apoptosis.
Bone marrow failure and the telomeropathies.
Combined Detection of mRNA Expression of Alpha-Fetoprotein in Peripheral Blood and Telomerase Activity of Monocytes in Hepatocellular Carcinoma Patients.
Determinants of Elevated Alkaline Phosphatase in Patients Infected with HIV.
Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma.
Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma.
Familial pulmonary fibrosis.
Hepatic histopathology and clinical characteristics associated with antiretroviral therapy in HIV patients without viral hepatitis.
Hepatic steatosis and lactic acidosis caused by stavudine in an HIV-infected patient.
Impact of highly active antiretroviral therapy on the spectrum of liver disease in HCV-HIV coinfection.
Liver Transplantation for Decompensated Cirrhosis Secondary to Telomerase Reverse Transcriptase (TERT) Mutation.
Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.
Mimicry between the hepatitis B virus DNA polymerase and the antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis B virus infection.
Nonalcoholic fatty liver disease in HIV-infected persons: epidemiology and the role of nucleoside reverse transcriptase inhibitors.
Nucleoside reverse-transcriptase inhibitor use, cirrhosis, and end-stage liver disease in HIV-infected patients.
Pathogenic TERT promoter variants in telomere diseases.
Precancerous hepatic nodules had significant levels of telomerase activity determined by sensitive quantitation using a hybridization protection assay.
Prevention of critical telomere shortening by oestradiol in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosis.
Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis.
Quantitative analysis and in situ localization of human telomerase RNA in chronic liver disease and hepatocellular carcinoma.
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis.
Recent progress in dyskeratosis congenita.
Significance of telomerase activity in the diagnosis of small differentiated hepatocellular carcinoma.
Surgical significance of telomerase activity in noncancerous liver tissue from patients with hepatocellular carcinoma.
Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease.
Telomerase activity in hepatocellular carcinoma and adjacent liver tissues.
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.
Telomerase activity in peripheral blood for diagnosis of hepatoma.
Telomerase activity in peripheral blood mononuclear cells as a universal scale for quantitative measurement of telomerase activation on the example of liver diseases.
Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.
Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.
Telomerase gene mutations are associated with cirrhosis formation.
Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease.
Telomerase reverse transcriptase mRNA expression and telomerase activity in hepatocellular carcinoma.
Telomerase Variants in Patients with Cirrhosis Awaiting Liver Transplantation.
Telomerase: a key player in the pathogenesis of non-alcoholic fatty liver disease?
Telomere and telomerase in chronic liver disease and hepatocarcinoma.
Telomere Dysfunction Activates p53 and Represses HNF4? Expression Leading to Impaired Human Hepatocyte Development and Function.
Telomere length in human liver diseases.
Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations.
Telomere, telomerase and liver disease.
Telomeres, NAFLD and Chronic Liver Disease.
The role of telomeres and telomerase in cirrhosis and liver cancer.
[Clinical significance of telomerase activity in precancerous lesion of the liver (adenomatous hyperplasia)]
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
Liver Diseases, Alcoholic
Telomerase reverse transcriptase acts in a feedback loop with NF-?B pathway to regulate macrophage polarization in alcoholic liver disease.
Liver Failure
Detection of telomerase reverse transcriptase mRNA in peripheral blood mononuclear cells of patients with liver failure.
High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes.
Liver Failure, Acute
Establishment and characterization of immortalized porcine hepatocytes for the study of hepatocyte xenotransplantation.
Liver Neoplasms
A CRISPR-driven colorimetric code platform for highly accurate telomerase activity assay.
A homeopathic nosode, Hepatitis C 30 demonstrates anticancer effect against liver cancer cells in vitro by modulating telomerase and topoisomerase II activities as also by promoting apoptosis via intrinsic mitochondrial pathway.
A scalable and reproducible preparation for the antitumor protein TLC, a human-derived telomerase inhibitor.
A stable trypsin inhibitor from Chinese dull black soybeans with potentially exploitable activities.
Amarogentin Induces Apoptosis of Liver Cancer Cells via Upregulation of p53 and Downregulation of Human Telomerase Reverse Transcriptase in Mice.
Application of machine learning to large in-vitro databases to identify cancer cell characteristics: telomerase reverse transcriptase (TERT) expression.
CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells.
Combination of HSV1-TK/shTERT by retrovirus vector inhibits hepatocellular carcinoma cell growth in vitro and in vivo.
Double mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR.
Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.
HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2.
Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically.
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis.
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor.
Sinusoidal swinging dynamics of the telomere repair and cell growth activation functions of telomerase in rat liver cancer cells.
Stabilizing G-quadruplex DNA by a scissors-shaped binaphthyl derivative through the entangling mode: cooperation of binaphthylene and the ethoxy chain.
Telomerase activity (TMA) in tumour and peritumoural tissues in a rat liver cancer model.
Telomerase activity and telomerase catalytic subunit in hepatocellular carcinoma.
Telomerase reverse transcriptase suppression inhibits cell proliferation and promotes cell apoptosis in hepatocellular cancer.
Telomeres and Telomerase in the Development of Liver Cancer.
The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells.
The role of telomeres and telomerase in cirrhosis and liver cancer.
[Circadian rhythms of DNA synthesis and telomerase expression in hepatic cancer transplanted in nude mice]
[Effects of tea polyphenols and tea pigments on telomerase activity of HepG2 cells]
[Hammerhead ribozyme against human telomerase catalytic subunit (hTERT) induced apoptosis of liver cancer cells]
[Progress on prevention and treatment of Chinese medicine to molecular mechanism of liver cancer]
[Reversing malignant phenotypes of liver cancer cell lines with antisense gene to human telomerase reverse transcriptase]
[Studies on telomerase reverse transcriptase components and liver cancer].
[TELOMERASE ACTIVITY AS A POTENTIAL BIOMARKER FOR PREOPERATIVE DIFFERENTIAL DIAGNOSIS OF CYSTIC NEOPLASMS OF THE LIVER].
[Telomerase activity in liver cancer and the adjacent tissue]
Lung Abscess
Detection of telomerase activity in bronchial lavage as an adjunct to cytological diagnosis in lung cancer.
Lung Diseases
A case of laryngeal carcinoma in a young adult with dyskeratosis congenita.
A comparative study of telomerase activity in sputum, bronchial washing and biopsy specimens of lung cancer.
Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease.
Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.
hTERT Gene Amplification and Clinical Significance in Pleural Effusions of Patients With Lung Cancer.
hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms.
Natural History of Pulmonary Fibrosis in Two Subjects with the Same Telomerase Mutation.
PINX1 and TERT Are Required for TNF-?-Induced Airway Smooth Muscle Chemokine Gene Expression.
Subclinical Lung Disease, Macrocytosis and Premature Graying in Kindreds with Telomerase (TERT) Mutations.
Telomerase activity as a novel marker of lung cancer and immune-associated lung diseases.
Telomerase and Telomere Length in Pulmonary Fibrosis.
Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.
Telomere Length is a Determinant of Emphysema Susceptibility.
[A preliminary study on telomerase activity in lung cancer patients' bronchoscopically biopsied specimens.]
[Detection of telomerase activity in bronchoscopic brush-off cells in lung cancer patients]
[Determination of telomerase activity in BALF cells from lung cancer patients]
[Study on the clinical value of telomerase activity in exfoliated cells of sputum from lung cancer patients.]
[The clinical significance of detection of telomerase in bronchoalveolar lavage liquid in patients with lung cancer].
Lung Diseases, Interstitial
Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis.
Rapid and Progressive Pulmonary Fibrosis in 2 Families with DNA Repair Deficiencies of Undetermined Etiology.
Telomerase and Telomere Length in Pulmonary Fibrosis.
Telomerase deficiency does not alter bleomycin-induced fibrosis in mice.
Telomerase gene variants and telomere shortening in patients with silicosis or asbestosis.
Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.
The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications.
Lung Injury
Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response.
Proliferation of adult human bronchial epithelial cells without a telomere maintenance mechanism for over 200 population doublings.
Regulation of PINX1 expression ameliorates lipopolysaccharide-induced lung injury and alleviates cell senescence during the convalescent phase through affecting the telomerase activity.
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.
[Role of pulmonary stem cells labeled with bromodeoxyuridine and telomerase reverse transcriptase in hyperoxic lung injury in neonatal rats]
Lung Neoplasms
17-DMAG-loaded nanofibrous scaffold for effective growth inhibition of lung cancer cells through targeting HSP90 gene expression.
A comparative study of telomerase activity in sputum, bronchial washing and biopsy specimens of lung cancer.
A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer.
A new mutL homolog 1 c.1896+5G>A germline mutation detected in a Lynch syndrome-associated lung and gastric double primary cancer patient.
A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A single quantum dot-based biosensor for telomerase assay.
A tumor-activatable peptide supramolecular nanoplatform for the delivery of dual-gene targeted siRNAs for drug-resistant cancer treatment.
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
Acetone extract of Bupleurum scorzonerifolium inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing telomerase activity.
Adenovirus-mediated and tumor-specific transgene expression of the sodium-iodide symporter from the human telomerase reverse transcriptase promoter enhances killing of lung cancer cell line in vitro.
Adenovirus-mediated HSV-TK gene therapy using the human telomerase promoter induced apoptosis of small cell lung cancer cell line.
Adenovirus-mediated suicide SCLC gene therapy using the increased activity of the hTERT promoter by the MMRE and SV40 enhancer.
Alternative splicing, but not allelic loss, of the FHIT gene increases with development of lung cancer.
Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer.
Analysis of mutant p53 and telomerase activity in non-small cell lung cancer.
Analysis of spontaneous tumor-specific CD4 T cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response.
Antiadhesive effects of GRN163L--an oligonucleotide N3'->P5' thio-phosphoramidate targeting telomerase.
Application of telomerase activity for screening of primary lung cancer in broncho-alveolar lavage fluid.
Association between the telomerase reverse transcriptase (TERT) rs2736098 polymorphism and cancer risk: evidence from a case-control study of non-small-cell lung cancer and a meta-analysis.
Association of a functional tandem repeats in the downstream of human telomerase gene and lung cancer.
Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population.
Association of p53 gene mutation and telomerase activity in resectable non-small cell lung cancer.
Association of telomerase expression with successful heterotransplantation of lung cancer.
Associations among telomerase activity, p53 protein overexpression, and genetic instability in lung cancer.
Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
BIBR1532, a Selective Telomerase Inhibitor, Enhances Radiosensitivity of Non-Small Cell Lung Cancer Through Increasing Telomere Dysfunction and ATM/CHK1 Inhibition.
Can CYP1A1 siRNA be an effective treatment for lung cancer?
Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.
Case-Control Study on Impact of the Telomerase Reverse Transcriptase Gene Polymorphism and Additional Single Nucleotide Polymorphism (SNP)- SNP Interaction on Non-Small Cell Lung Cancers Risk in Chinese Han Population.
CCND1 messenger RNA expression is correlated with EGFR mutation status in lung cancer.
Chidamide-induced ROS accumulation and miR-129-3p-dependent cell cycle arrest in non-small lung cancer cells.
Circulating DNA is a useful prognostic factor in patients with advanced non-small cell lung cancer.
Circulating Long Noncoding RNAs Act as Diagnostic Biomarkers in Non-Small Cell Lung Cancer.
Circulating plasma DNA as diagnostic biomarker in non-small cell lung cancer.
Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical trial.
Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer.
Clinical Characteristics and Prognostic Significance of TERT Promoter Mutations in Cancer: A Cohort Study and a Meta-Analysis.
Clinical impact of serum transforming growth factor-alpha mRNA as a predictive biomarker for the prognosis of fulminant hepatitis.
Clinical significance of CYFRA21-1, Scc-Ag and telomerase activity in serum and pleural effusion of patients with squamous-cell lung cancer.
Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer.
Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer.
Combination of multiple gene markers to detect circulating tumor cells in the peripheral blood of patients with non-small cell lung cancer using real-time PCR.
Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft.
Combining Telomerase Reverse Transcriptase Genetic Variant rs2736100 with Epidemiologic Factors in the Prediction of Lung Cancer Susceptibility.
Comparison between effects of free curcumin and curcumin loaded NIPAAm-MAA nanoparticles on telomerase and PinX1 gene expression in lung cancer cells.
Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.
Comparison of telomerase activity between malignant and tuberculous pleural effusions.
Cooperative role of telomerase activity and p16 expression in the prognosis of non-small-cell lung cancer.
Correlation between morphology and human telomerase gene amplification in bronchial brushing cells for the diagnosis of lung cancer.
Correlation between telomerase expression and terminal restriction fragment length ratio in non-small cell lung cancer--an adjusted measurement and its clinical significance.
CPSF4 activates telomerase reverse transcriptase and predicts poor prognosis in human lung adenocarcinomas.
Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells.
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands.
Detecting cell-free circulating hTERT mRNA in the plasma may identify a subset of nonsmall cell lung cancer patients.
Detection of circulating carcinoma cells by telomerase activity.
Detection of human telomerase reverse transcriptase mRNA in cells obtained by lavage of the pleura is not associated with worse outcome in patients with stage I/II non-small cell lung cancer: Results from Cancer and Leukemia Group B 159902.
Detection of telomerase activity in bronchial lavage as an adjunct to cytological diagnosis in lung cancer.
Detection of telomerase activity in cultured cells and tumor tissue of lung carcinoma by modified telomeric repeat amplification protocol.
Detection of telomerase activity in lung cancer tissues.
Detection of telomerase expression in mediastinal lymph nodes of patients with lung cancer.
Development of a cancer-targeted tissue-specific promoter system.
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours.
Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer.
Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model.
Discriminating association of a common telomerase reverse transcriptase promoter polymorphism with telomere parameters in non-small cell lung cancer with or without epidermal growth factor receptor mutation.
Disruption of the non-canonical WNT pathway in lung squamous cell carcinoma.
DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value.
Dual roles of a variable number of tandem repeat polymorphism in the TERT gene in lung cancer.
Early Detection of Recurrence in Patients With Locally Advanced Non-Small-Cell Lung Cancer via Circulating Tumor Cell Analysis.
Effect of plasmid-mediated RNA interference targeting telomerase reverse transcriptase on lung cancer cells.
Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA.
EGF upregulates RFPL3 and hTERT via the MEK signaling pathway in non?small cell lung cancer cells.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
Elevation of telomerase activity positively correlates to poor prognosis of patients with non-small cell lung cancer.
Epidermal growth factor activates telomerase activity by direct binding of Ets-2 to hTERT promoter in lung cancer cells.
Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter--effect on telomerase expression and telomere length maintenance in non-small cell lung cancer.
Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease.
Expression and alternative splicing pattern of human telomerase reverse transcriptase in human lung cancer cells.
Expression of human telomerase subunit genes in primary lung cancer and its clinical significance.
Expression of telomerase activity, telomerase RNA component and telomerase catalytic subunit gene in lung cancer.
Expression of telomerase hTERT in human non-small cell lung cancer and its correlation with c-myc gene.
Expression of telomeric repeat binding factor 1 protein in nonsmall cell lung cancer with human telomerase reverse transcriptase positive.
Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line.
Gene silencing effect of SiRNA-magnetic modified with biodegradable copolymer nanoparticles on hTERT gene expression in lung cancer cell line.
Genetic Polymorphism, Telomere Biology and Non-Small Lung Cancer Risk.
Genetic polymorphisms in the TERT-CLPTM1L region and lung cancer susceptibility in Chinese males.
Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer-A case-control study in a Chinese population.
Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer: a case-control study in northeast Chinese male population.
Genetic polymorphisms of TERT and CLPTM1L, cooking oil fume exposure, and risk of lung cancer: a case-control study in a Chinese non-smoking female population.
Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in a Chinese population.
Genetics of lung-cancer susceptibility.
Ginger extract inhibits human telomerase reverse transcriptase and c-Myc expression in A549 lung cancer cells.
Ginger Extract Promotes Telomere Shortening and Cellular Senescence in A549 Lung Cancer Cells.
High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.
Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast.
hTERT Gene Amplification and Clinical Significance in Pleural Effusions of Patients With Lung Cancer.
hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines.
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance.
Immunohistochemichal expression of biomarkers: a comparative study between diagnostic bronchial biopsies and surgical specimens of non-small-cell lung cancer.
Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination.
In vitro activation of hTERT-specific T cell responses in lung cancer patients following chemotherapy.
In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor.
Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell lung cancer.
Increased lung cancer risk associated with the TERT rs2736100 polymorphism: an updated meta-analysis.
Increased risk of developing lung cancer in Asian patients carrying the TERT rs2736098 G>A polymorphism: evidence from 3,354 cases and 3,518 controls.
Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells.
Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells.
Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer.
Inhibition of Telomerase Activity Using an EGFP-Intron Splicing System Encoding Multiple RNAi Sequences.
Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes.
Irradiation-induced telomerase activity and the risk of lung cancer: a pilot case-control study.
KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth.
Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC.
Lack of telomerase activity in lung carcinoids is dependent on human telomerase reverse transcriptase transcription and alternative splicing and is associated with long telomeres.
LncRNA MEG3 inhibits non-small cell lung cancer via interaction with DKC1 protein.
Long-Term Outcomes of a Phase I Study With UV1, a Second Generation Telomerase Based Vaccine, in Patients With Advanced Non-Small Cell Lung Cancer.
Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.
Mechanistic in vitro studies: What they have told us about carcinogenic properties of elongated mineral particles (EMPs).
Modulating telomerase activity in tumor patients by targeting dyskerin binding site for hTR.
Modulation of telomere shelterin by TRF1 [corrected] and TRF2 interacts with telomerase to maintain the telomere length in non-small cell lung cancer.
Molecular markers in lung cancer: prognostic role and relationship to smoking.
Molecular staging of lung cancer: real-time polymerase chain reaction estimation of lymph node micrometastatic tumor cell burden in stage I non-small cell lung cancer--preliminary results of Cancer and Leukemia Group B Trial 9761.
Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.
Multiscale in situ analysis of the role of dyskerin in lung cancer cells.
MYC and human telomerase gene (TERC) copy number gain in early-stage non-small cell lung cancer.
Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer.
Nuclear translocation of telomerase reverse transcriptase and calcium signaling in repression of telomerase activity in human lung cancer cells by fungal immunomodulatory protein from Ganoderma tsugae.
Optimized tumor cryptic peptides: the basis for universal neo-antigen-like tumor vaccines.
P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment.
Peripheral blood telomere alterations in ground glass opacity (GGO) lesions may suggest malignancy.
Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity.
Polymorphisms in the TERT gene are associated with lung cancer risk in the Chinese Han population.
Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation.
Prevalence of telomerase activity in human cancer.
Prognostic factors in resected stage I non-small-cell lung cancer: a multivariate analysis of six molecular markers.
Prognostic impact of telomerase activity in non-small cell lung cancers.
Prognostic significance of telomerase activity and some tumor markers in non-small cell lung cancer.
Prognostic significance of telomerase polymorphism in non-small cell lung cancer.
Prognostic value of hTERT mRNA expression in surgical samples of lung cancer patients: the European Early Lung Cancer Project.
Pterostilbene as a Potential Novel Telomerase Inhibitor: Molecular Docking Studies and its In Vitro Evaluation.
Purification and characterization of a novel lectin with antiphytovirus activities from the wild mushroom Paxillus involutus.
Quantification in the serum of the catalytic fraction of reverse telomerase: a useful prognostic factor in advanced non-small cell lung cancer.
Quantification of alternative splicing variants of human telomerase reverse transcriptase and correlations with telomerase activity in lung cancer.
Quantification of free circulating DNA as a diagnostic marker in lung cancer.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Real-time RT-PCR quantification of human telomerase reverse transcriptase splice variants in tumor cell lines and non-small cell lung cancer.
Relationship between 3p deletions and telomerase activity in non-small-cell lung cancer: prognostic implications.
RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer.
Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells.
RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells.
Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population.
Silencing tankyrase and telomerase promotes A549 human lung adenocarcinoma cell apoptosis and inhibits proliferation.
Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells.
Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients.
Study of telomerase activity in pleural lavage fluid specimens in patients with non-small-cell lung cancer and its clinical significance.
Targeting KRAS mutation-bearing lung cancer in vivo by pulmonary surfactant-adenovirus-mediated gene transfer.
Telomerase activity and Bcl-2 expression in non-small cell lung cancer.
Telomerase activity and expression of the telomerase catalytic subunit gene in non-small cell lung cancer: correlation with decreased apoptosis and clinical prognosis.
Telomerase activity and serum levels of p53 protein as prognostic factors of survival in patients with advanced non-small cell lung cancer.
Telomerase activity and telomere length in human tumor cells with acquired resistance to anticancer agents.
Telomerase activity and the risk of lung cancer.
Telomerase activity as a novel marker of lung cancer and immune-associated lung diseases.
Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer.
Telomerase activity during carcinogenesis in the bronchus.
Telomerase activity in endoscopically visible lung cancer.
Telomerase activity in lung cancer cell lines and tissues.
Telomerase activity in lung cancer cells obtained from bronchial washings.
Telomerase activity in non-small cell lung cancer.
Telomerase activity in pulmonary neuroendocrine tumors: correlation with histologic subtype (MS-0060).
Telomerase activity in small-cell and non-small-cell lung cancers.
Telomerase activity in sputum and telomerase and its components in biopsies of advanced lung cancer.
Telomerase activity in transthoracic fine needle biopsy aspirates as a marker of peripheral lung cancer.
Telomerase activity in transthoracic fine-needle biopsy aspirates from non-small cell lung cancer as prognostic factor of patients' survival.
Telomerase activity, telomere length and hTERT DNA methylation in peripheral blood mononuclear cells from monozygotic twins with discordant smoking habits.
Telomerase and Telomere Length in Pulmonary Fibrosis.
Telomerase as a potential marker for inflammation and cancer detection in bronchial washing: A prospective study.
Telomerase expression in lung preneoplasia and neoplasia.
Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer.
Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner.
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial.
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer.
Telomerase reverse transcriptase rs2736098 polymorphism is associated with lung cancer: A meta-analysis.
Telomerase--a potential molecular marker of lung and cervical cancer.
Telomerase-mediated lifespan extension of human bronchial cells does not affect hexavalent chromium-induced cytotoxicity or genotoxicity.
Telomerase-Mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance.
Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status.
Telomere shortening is associated with poor prognosis and telomerase activity correlates with DNA repair impairment in non-small cell lung cancer.
Telomeres and telomerase in lung cancer.
Template-ready PCR method for detection of human telomerase reverse transcriptase mRNA in sputum.
TERT genetic polymorphism rs2736100 was associated with lung cancer: a meta-analysis based on 14,492 subjects.
The Effects of Nanoencapsulated Curcumin-Fe3O4 on Proliferation and hTERT Gene Expression in Lung Cancer Cells.
The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer.
The green tea polyphenol, epigallocatechin-3-gallate inhibits telomerase and induces apoptosis in drug-resistant lung cancer cells.
The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells.
The level of telomere dysfunction determines the efficacy of telomerase-based therapeutics in a lung cancer cell line.
The role of gene expression profiling in early-stage non-small cell lung cancer.
The sequence of vessel ligation affects tumor release into the circulation.
The value of chest CT scan and tumor markers detection in sputum for early diagnosis of peripheral lung cancer.
Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA.
TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells.
Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2'-O-Methyl-RNA.
Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells.
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization.
Ultrasensitive detection of telomerase activity in lung cancer cells with quencher-free molecular beacon-assisted quadratic signal amplification.
Vaccination of patients with advanced non-small-cell lung cancer with an optimized cryptic human telomerase reverse transcriptase peptide.
Vorinostat represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells.
[A preliminary study on telomerase activity in lung cancer patients' bronchoscopically biopsied specimens.]
[A study on selective killing effect of Hsv-tk/GCV driven by human telomerase catalytic subunit promoter on human lung cancer cell A549]
[A study on the telomerase activity in lung cancer and its clinical significance.]
[An experimental study of telomerase reverse transcriptase (hTERT) DNAzyme on growth of A549/DDP cells.]
[An experimental study on targeting suicide gene therapy for lung cancer with HSV-TK driven by hTERT promoter]
[Clinical Application and Challenges of Telomere and Telomerase Research ?in Lung Cancer].
[Clinical significance of telomerase activity in lung cancer.]
[Cloning of human telomerase catalytic subunit gene promoter and studying on its specific transcriptional activities in human lung cancer cells.]
[Cloning of human telomerase reverse transcriptase promoter for targeted cancer therapy]
[Detection and significance of HPV16, 18 infection, P53 overexpression and telomerase activity in patients with lung cancer]
[Detection of telomerase activity in bronchoscopic brush-off cells in lung cancer patients]
[Detection of telomerase activity in bronchoscopic brush-off samples in patients with lung cancer]
[Detection of telomerase activity in human lung cancer.]
[Detection of telomerase activity in the blood of patients with lung cancer.]
[Detection of telomerase activity level in human non-small-cell lung cancer]
[Detection of telomerase hTERT gene expression of exfoliated cell in broncho-alveolar lavage fluid]
[Determination of telomerase activity in BALF cells from lung cancer patients]
[Diagnostic significance of combining telomerase activity with CYFRA21-1 level in differentiating malignant pleural effusion caused by lung cancer from benign pleural effusion]
[Diagnotic value of the combined determination of telomerase activity in induced sputum, pleural effusion and fiberobronchoscopic biopsy samples in lung cancer]
[Effect of selenium dioxide on proliferation, apoptosis, and elomerase activity of human lung cancer cell line in vitro]
[Epidemiology of lung cancer in former poison-gas workers and molecular approaches to lung cancer]
[Expression and clinical significance of telomerase catalytic subunit gene in lung cancer and its correlations with genes related to drug resistance and apoptosis]
[Expression of human telomerase in lung cancer:A meta-analysis of diagnostic test.]
[Expression of multidrug resistance-associated gene in non-small cell lung cancer and its correlations with telomerase reverse transcriptase and genes related to apoptosis]
[Expression of telomerase activity in human lung cancer.]
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
[hTERT promoter-based conditionally replicative adenoviruses are useful for lung cancer and other solid cancer treatment]
[Human telomerase RNA (hTR) expression in lung cancer in the Gejiu and Xuanwei regions of Yunnan]
[Influence of nicotine addiction on telomerase activity in malignant non-small cell lung tumors]
[Inhibition of anti-sense human telomerase reverse transcriptase (hTERT) retroviral vector on lung cancer cells]
[Inhibition of lung cancer cell line growth in vitro by telomerase anti-sense oligonucleotides.]
[Inhibition of telomerase activity and induction of apoptosis in lung cancer cell by human telomerase reverse transcriptase gene antisense oligodeoxynucleotide]
[Inhibitory effect of hTERT dsRNA on telomerase activity in lung carcinoma cell line A549]
[Location expression of human telomerase reverse transcriptase in lung cancer, benign lesion and normal lung tissue]
[Lung cancer: progress in diagnosis and treatment. IV. Related topics: 1. Telomere and telomerase, new targets for diagnosis and treatment of lung cancer]
[Relationship among telomerase activity, telomerase RNA and telomerase catalytic subunit gene expression and their significance in non small-cell lung cancer]
[Study on cloning of hTERT promoter and its targeting transcriptional activities in telomerase-positive lung cancer cells]
[Study on growth inhibition of implanted tumor in nude mice by antisense oligodeoxynucleotide targeting telomerase RNA.]
[Study on telomerase activity and its clinical value in human non small cell lung cancer]
[Study on the clinical value of telomerase activity in exfoliated cells of sputum from lung cancer patients.]
[Study on the inhibitory effect of antisense PNA of telomerase for growth of lung cancer cell lines in vitro.]
[Study on the relationship between telomerase gene and telomerase activity in lung cancer tissue.]
[Telomerase activity as a novel marker of lung cancer]
[Telomerase activity in human non-small cell lung cancer (NSCLC)]
[Telomerase activity in human primary lung caner.]
[Telomerase activity in lung cancer and adjacent peritumoral tissues determined by TRAP-SYBR green assay]
[Telomerase in lung cancer. Testing the activity of the "immortaligy enzyme" bronchial biopsies increases the diagnostic yield in cases of suspected peripheral bronchogenic carcinomas]
[Telomere and telomerase in lung cancer]
[The advantage of an in situ TRAP assay for the detection of telomerase activity using bronchial washings obtained from lung cancer patients]
[The clinical significance of detection of telomerase in bronchoalveolar lavage liquid in patients with lung cancer].
[The diagnostic value of telomerase activity in bronchial biopsy specimen for lung cancer]
[The Expression of hTERT mRNA and p16 Protein in Non-small Cell Lung Cancer.]
[The value of detecting telomerase activity on early diagnosis of lung cancer.]
[Values of telomerase in the diagnosis and treatment of lung cancer.]
[Vascular endothelial growth factor promotes hematogenous metastasis of cancer cells in patients with non-small cell lung cancer]
Lupus Erythematosus, Systemic
Abnormal telomerase activity and telomere length in T and B cells from patients with systemic lupus erythematosus.
Changes in the expression of telomere maintenance genes might play a role in the pathogenesis of systemic lupus erythematosus.
Evidence in patients with systemic lupus erythematosus of the presence of antibodies against RNA-dependent DNA polymerase of baboon endogenous virus.
Expression Pattern of Telomerase Reverse Transcriptase (hTERT) Variants and Bcl-2 in Peripheral Lymphocytes of Systemic Lupus Erythematosus Patients.
Telomerase activity and telomere length of peripheral blood mononuclear cells in SLE patients.
Telomerase activity in B and T lymphocytes of patients with systemic lupus erythematosus.
The telomere/telomerase system in autoimmune and systemic diseases.
Type C oncornavirus isolation studies in systemic lupus erythematosus. II. Attempted detection by viral RNA-dependent DNA polymerase assay.
[Abnormalities in lymphocyte telomerase activity and telomere length in systemic lupus erythematosus]
[Telomerase activity and telomere length in CD4+,CD8+ and CD19+ lymphocytes from patients with systemic lupus erythematosus]
[Telomeres and telomerase: Relevance and future prospects in systemic lupus erythematosus.]
Lymphadenopathy
Quantitative measurement of telomerase activity in lymphadenopathy: correlation with histologic features and human immunodeficiency virus-1 infection.
Lymphangioleiomyomatosis
Expression of human telomerase reverse transcriptase in lymphangioleiomyomatosis.
Lymphatic Metastasis
An anti-apoptosis gene, survivin and telomerase expression in gastric cancer.
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
Clinical usefulness of telomerase assay for the detection of lymph node metastasis in patients with oral malignancy.
Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer.
Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma.
Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Elevation of telomerase activity positively correlates to poor prognosis of patients with non-small cell lung cancer.
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.
Gastric cancer with high telomerase activity shows rapid development and invasiveness.
High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.
Lymph node metastases, not human telomerase reverse transcriptase or p53 proteins, as the strongest prognostic factor for survival in early stage cervical cancer.
Missing association between telomerase activity and clinicopathological features in patients with early stage carcinoma of the cervix.
Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.
Nuclear translocation of telomerase reverse transcriptase is a critical process in lymphatic metastasis of nasopharyngeal carcinoma.
Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases.
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis.
Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma.
Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma.
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Telomerase activity analysis of esophageal carcinoma using microdissection-TRAP assay.
Telomerase activity and human telomerase reverse transcriptase expression in colorectal carcinoma.
Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in gynecological tumors.
Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.
Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.
Telomerase activity of blood samples and recurrence of colorectal cancer.
Telomerase activity significantly correlates with cell differentiation, proliferation and lymph node metastasis in colorectal carcinomas.
Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study.
Telomerase expression in human breast cancer with and without lymph node metastases.
Telomerase reverse transcriptase methylation predicts lymph node metastasis and prognosis in patients with gastric cancer.
Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.
The clinical significance of PINX1 expression in papillary thyroid carcinoma.
The influence of reactivation of the telomerase in tumour tissue on the prognosis of squamous cell carcinomas in the head and neck.
[Analysis of telomerase activity in esophageal carcinoma using microdissection telomeric repeat amplification protocol assay]
[Clinical significance of telomerase activity in lung cancer.]
[Detection of telomerase activity in laryngeal carcinoma and the association between telomerase activity and lymphatic metastasis]
[Expression of telomerase activity in human lung cancer.]
[Study on telomerase activity and its clinical value in human non small cell lung cancer]
[Telomerase activity in cervical cancer and its precursor lesion]
[Telomerase activity in gastric cancer and premalignant lesions: determination and its clinical significance]
[Telomerase activity in infiltration ductal carcinoma of breast]
[Telomerase activity in stool of patients with colorectal cancer]
[The experimental study on telomerase activity and expression of p53 and c-myc genes in tongue cancer]
[The study on the role of telomerase activity in human nasopharyngeal carcinoma]
Lymphocytic Choriomeningitis
Induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory CD8+ T cells.
Lymphocytosis
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Lymphoma
A novel ribonuclease with antiproliferative activity toward leukemia and lymphoma cells and HIV-1 reverse transcriptase inhibitory activity from the mushroom, Hohenbuehelia serotina.
ALK Protein Expression is Related to Neuroblastoma Aggressiveness, But is Not Independent Prognostic Factor.
Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition.
Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer.
Characterization of an RNA-directed DNA-polymerase from a cell line derived from a radiation-induced lymphoma in mice.
Clinical relevance of telomerase activity in primary gastric lymphoma.
Clinicopathologic, cytogenetic, and molecular studies of 13 Chinese Patients with Ki-1 anaplastic large cell lymphoma. Special emphasis on the tumor response to 13-cis retinoic acid.
Cytochrome P450 17 (CYP17) Is Involved in Endometrial Cancinogenesis Through Apoptosis and Invasion Pathways.
Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors.
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Detection of chimaeric transcripts of the immunoglobulin heavy chain and BCL6 genes by reverse-transcriptase polymerase chain reaction in B-cell non-Hodgkin's lymphomas.
Differential expression of the HHV-8 vGCR cellular homolog gene in AIDS-associated and classic Kaposi's sarcoma: potential role of HIV-1 Tat.
Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.
Down-regulation of telomerase activity in malignant lymphomas by radiation and chemotherapeutic agents.
Effects of irradiation on telomerase activity in human lymphoma and myeloma cell lines.
Efficacy of Pemetrexed-Based Chemotherapy in Patients with ROS1 Fusion-Positive Lung Adenocarcinoma Compared with in Patients Harboring Other Driver Mutations in East Asian Populations.
Epstein-Barr virus-encoded RNAs (EBERs) complement the loss of Herpesvirus telomerase RNA (vTR) in virus-induced tumor formation.
Exploring hTERT promoter methylation in cutaneous T-cell lymphomas.
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
Granulocyte colony-stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cells and may prevent telomere attrition after chemotherapy.
Herpesvirus telomerase RNA (vTR) with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.
Herpesvirus telomerase RNA(vTR)-dependent lymphoma formation does not require interaction of vTR with telomerase reverse transcriptase (TERT).
High co-expression of PD-L1 and HIF-1? correlates with tumour necrosis in pulmonary pleomorphic carcinoma.
Hodgkin and Reed-Sternberg cells of classical Hodgkin's disease overexpress the telomerase RNA template (hTR).
Induction of telomerase activity in avian lymphoblastoid cell line transformed by Marek's disease virus, MDCC-MSB1.
Integration patterns of HTLV-I provirus in relation to the clinical course of ATL: frequent clonal change at crisis from indolent disease.
MET Exon 14 Skipping Mutations in Lung Adenocarcinoma: Clinicopathologic Implications and Prognostic Values.
Molecular cloning of the feline telomerase reverse transcriptase (TERT) gene and its expression in cell lines and normal tissues.
Myc, Cdk2 and cellular senescence: Old players, new game.
Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton's lymphoma ascites tumor.
Omacetaxine mepesuccinate induces apoptosis and cell cycle arrest, promotes cell differentiation, and reduces telomerase activity in diffuse large B?cell lymphoma cells.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Peripheral T-cell lymphoma with Toutonlike tumor giant cells associated with HIV infection: report of two cases.
Quantitative measurement of telomerase activity in lymphadenopathy: correlation with histologic features and human immunodeficiency virus-1 infection.
Real-time quantitative telomeric repeat amplification protocol assay for the detection of telomerase activity.
Regression of gastric mucosa-associated lymphoid tissue lymphoma with reduced telomerase activity after eradication of Helicobacter pylori.
Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins.
Rhesus macaque rhadinovirus-associated non-Hodgkin lymphoma: animal model for KSHV-associated malignancies.
RNA-dependent DNA polymerase associated with a simian lymphoid cell line derived from a Herpesvirus saimiri-induced lymphoma.
Role of diallyl disulfide-mediated cleavage of c-Myc and Sp-1 in the regulation of telomerase activity in human lymphoma cell line U937.
siRNA targeting LMP1-induced apoptosis in EBV-positive lymphoma cells is associated with inhibition of telomerase activity and expression.
Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma.
Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and related properties of normal canine lymph node and canine lymphoma*.
Telomerase activity and telomerase reverse transcriptase catalytic subunit expression in canine lymphoma: correlation with Ki67 immunoreactivity.
Telomerase activity in B-cell non-Hodgkin lymphoma.
Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation.
Telomerase activity in cell lines and lymphoma originating from Bloom syndrome.
Telomerase activity in central nervous system malignant lymphoma.
Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage.
Telomerase activity in clinically normal dogs and dogs with malignant lymphoma.
Telomerase activity in Hodgkin's disease.
Telomerase activity in microdissected human gliomas.
Telomerase activity in patients with chronic myeloid leukemia and lymphoma.
Telomerase activity in peripheral blood mononuclear cells after whole body irradiation.
Telomerase activity in preleukemia and acute myelogenous leukemia.
Telomerase activity in reactive and neoplastic lymphoid tissues: infrequent detection of activity in Hodgkin's disease.
Telomerase activity in relation to pro- and anti-apoptotic protein expression in high grade non-Hodgkin's lymphomas.
Telomerase activity in thyroid malignancy.
Telomerase activity in vivo in human malignant hematopoietic cells.
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.
Telomerase Responsive Delivery of Doxorubicin from Mesoporous Silica Nanoparticles in Multiple Malignancies: Therapeutic Efficacies against Experimental Aggressive Murine Lymphoma.
Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas.
Telomerase. A target for anticancer therapy.
Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse.
Telomeres and telomerase in leukaemia and lymphoma.
Telomeres and telomerase in normal and malignant haematopoietic cells.
The effect of Bortezomib and Rapamycin on Telomerase Activity in Mantle Cell Lymphoma.
The helix-loop-helix protein Id2 is expressed differentially and induced by myc in T-cell lymphomas.
Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean".
Vaccination against Marek's disease reduces telomerase activity and viral gene transcription in peripheral blood leukocytes from challenged chickens.
[Analysis for telomerase activity in various hematologic disorders]
[Detection of telomerase activity in gastric cancer].
[Telomere DNA and telomerase of lymphoma-derived cell lines--telomere hypothesis for cell growth control]
Lymphoma, B-Cell
A vaccine targeting telomerase enhances survival of dogs affected by B-cell lymphoma.
Aberrant ERG expression associates with downregulation of miR-4638-5p and selected genomic alterations in a subset of diffuse large B-cell lymphoma.
Avian leukosis virus activation of an antisense RNA upstream of TERT in B-cell lymphomas.
Cellular lifespan and regenerative medicine.
Cytochrome P450 17 (CYP17) Is Involved in Endometrial Cancinogenesis Through Apoptosis and Invasion Pathways.
Differential cytotoxic effects of sodium meta-arsenite on human cancer cells, dental papilla stem cells and somatic cells correlate with telomeric properties and gene expression.
G-quadruplex antibody attenuates human gastric cancer cell proliferation and promotes apoptosis through hTERT/telomerase pathway.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Role of the functional MNS16A VNTR-243 variant of the human telomerase reverse transcriptase gene in progression and response to therapy of patients with non-Hodgkin's B-cell lymphomas.
Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphoma.
STAT5: From Pathogenesis Mechanism to Therapeutic Approach in Acute Leukemia.
Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma.
Telomerase activity and proliferation index in aggressive mature B-cell lymphoma: comparison to germinal center phenotypic markers.
Telomerase activity in B-cell non-Hodgkin lymphoma.
[Study on the expression of tankyrase in malignant hematopoietic cells and its relation with telomerase activity]
Lymphoma, B-Cell, Marginal Zone
Clinical relevance of telomerase activity in primary gastric lymphoma.
Regression of gastric mucosa-associated lymphoid tissue lymphoma with reduced telomerase activity after eradication of Helicobacter pylori.
Lymphoma, Large B-Cell, Diffuse
Aberrant ERG expression associates with downregulation of miR-4638-5p and selected genomic alterations in a subset of diffuse large B-cell lymphoma.
Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma.
Lymphoma, Large-Cell, Anaplastic
The helix-loop-helix protein Id2 is expressed differentially and induced by myc in T-cell lymphomas.
Lymphoma, Mantle-Cell
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage.
The effect of Bortezomib and Rapamycin on Telomerase Activity in Mantle Cell Lymphoma.
Lymphoma, Non-Hodgkin
Clinical relevance of telomerase activity in primary gastric lymphoma.
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Molecular approaches to the diagnosis and evaluation of lymphoid malignancies.
Peripheral blood telomerase activity in non-Hodgkin lymphoma.
Presence of a high-molecular-weight RNA and RNA-directed DNA polymerase in rabbit hereditary lymphosarcoma.
RNA-dependent DNA polymerase activity in canine lymphosarcoma.
Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphoma.
Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas.
Telomerase activity in B-cell non-Hodgkin lymphoma.
Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation.
Telomerase activity in oral cancer.
Telomerase activity in reactive and neoplastic lymphoid tissues: infrequent detection of activity in Hodgkin's disease.
Telomerase activity in relation to pro- and anti-apoptotic protein expression in high grade non-Hodgkin's lymphomas.
Telomerase activity in vivo in human malignant hematopoietic cells.
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.
Telomeres and telomerase in hematologic neoplasia.
TERC telomerase subunit gene copy number in different disease stages of non-hodgkin lymphoma and in hepatitis C.
Lymphoma, Primary Effusion
Rhesus macaque rhadinovirus-associated non-Hodgkin lymphoma: animal model for KSHV-associated malignancies.
Lymphoma, T-Cell
The CD44 receptor of the mouse LB T-cell lymphoma: analysis of the isoform repertoire and ligand binding properties by reverse-transcriptase polymerase chain reaction and antisense oligonucleotides.
Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.
Lymphoma, T-Cell, Cutaneous
Shortened telomere length is demonstrated in T-cell subsets together with a pronounced increased telomerase activity in CD4 positive T cells from blood of patients with mycosis fungoides and parapsoriasis.
Telomerase activity and telomere length in lymphocytes from patients with cutaneous T-cell lymphoma.
Telomerase functions beyond telomere maintenance in primary cutaneous T-cell lymphoma.
Lymphoma, T-Cell, Peripheral
Expression of telomerase reverse transcriptase in peripheral T-cell lymphoma.
Lymphopenia
Association of immune abnormalities with telomere shortening in autosomal-dominant dyskeratosis congenita.
Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus.
Lymphoproliferative Disorders
Cytokine mRNA profiles in Epstein-Barr virus-associated post-transplant lymphoproliferative disorders.
Telomerase activity and clinical progression in chronic lymphoproliferative disorders of B-cell lineage.
Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage.
Macular Degeneration
Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study.
Possible therapy for age-related macular degeneration using human telomerase.
Potential of melatonin to treat or prevent age-related macular degeneration through stimulation of telomerase activity.
Protection of Retinal Function by Nucleoside Reverse Transcriptase Inhibitors Following Retinal Ischemia/Reperfusion Injury.
[Experimental and clinical studies of mechanisms of the anti-aging effects of chemical compounds in Astragalus membranaceus (review).]
Magnesium Deficiency
Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.
Malaria
Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children.
Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study.
Identification of telomerase activity in gametocytes of Plasmodium falciparum.
New anti-malarial compounds from database searching.
P. berghei telomerase subunit TERT is essential for parasite survival.
Plasmodium falciparum telomerase: de novo telomere addition to telomeric and nontelomeric sequences and role in chromosome healing.
Stage specificity of Plasmodium falciparum telomerase and its inhibition by berberine.
Topological polar surface area: a useful descriptor in 2D-QSAR.
Malignant Catarrh
Detection of ovine herpesvirus 2 major capsid gene transcripts as an indicator of virus replication in shedding sheep and clinically affected animals.
Mania
Telomere length and hTERT in mania and subsequent remission.
Marek Disease
Comparative functional study of the viral telomerase RNA based on natural mutations.
Induction of telomerase activity in avian lymphoblastoid cell line transformed by Marek's disease virus, MDCC-MSB1.
Involvement of the oncoprotein c-Myc in viral telomerase RNA gene regulation during Marek's disease virus-induced lymphomagenesis.
Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene.
Telomeres and Telomerase: Role in Marek's Disease Virus Pathogenesis, Integration and Tumorigenesis.
The ICP27 protein of Marek's disease virus interacts with SR proteins and inhibits the splicing of cellular telomerase chTERT and viral vIL8 transcripts.
The RNA subunit of telomerase is encoded by Marek's disease virus.
Vaccination against Marek's disease reduces telomerase activity and viral gene transcription in peripheral blood leukocytes from challenged chickens.
Measles
Adult Measles - Case Reports of a Highly Contagious Disease.
Antimeasles Immunoglobulin G for Serologic Diagnosis of Otosclerotic Hearing Loss.
Detection of measles virus by reverse-transcriptase polymerase chain reaction in a placenta.
Diagnosis of Measles Pneumonia from Bronchoalveolar Lavage Fluid by Reverse-Transcriptase Polymerase Chain Reaction: Case Report.
Epidemiological and molecular investigation of a measles outbreak in Punjab, Pakistan, 2013-2015.
Histologic otosclerosis is associated with the presence of measles virus in the stapes footplate.
Measles virus prevalence in otosclerotic stapes footplate samples.
[Diagnosis of adult measles pneumonia from bronchoalveolar lavage fluid by reverse-transcriptase polymerase chain reaction]
Mediastinal Diseases
Detection of telomerase expression in mediastinal lymph nodes of patients with lung cancer.
Medulloblastoma
All trans-retinoic acid suppresses in vitro growth and down-regulates LIF gene expression as well as telomerase activity of human medulloblastoma cells.
hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors.
Immunohistochemical Profiling and Telomerase Activity of a Canine Medulloblastoma.
Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.
Molecular analysis of PinX1 in medulloblastomas.
Multidrug resistance gene expression in childhood medulloblastoma: correlation with clinical outcome and DNA ploidy in 29 patients.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Photodynamic effect in medulloblastoma: downregulation of matrix metalloproteinases and human telomerase reverse transcriptase expressions.
Reproducibility of the NanoString 22-gene molecular subgroup assay for improved prognostic prediction of medulloblastoma.
Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood.
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.
The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells.
Melanoma
6-alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): novel regulators of cell differentiation and proliferation.
6-Dithio-2'-deoxyguanosine analogs induce reactive oxygen species-mediated tumor cell apoptosis via bi-targeting thioredoxin 1 and telomerase.
Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions.
Aberrant hTERT promoter methylation predicts prognosis in Chinese patients with acral and mucosal melanoma: A CONSORT-compliant article.
Absence of telomerase activity and telemorase catalytic subunit mRNA in melanocyte cultures.
Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.
Anti-tumor effects of immunotherapeutic peptide on the treatment of hepatocellular carcinoma with HBc carrier.
Antitumor Activity of Small Double-Stranded Oligodeoxynucleotides Targeting Telomerase RNA in Malignant Melanoma Cells.
Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA.
Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase.
Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
Association between circulating tumor cells and prognosis in patients with stage III melanoma with sentinel lymph node metastasis in a phase III international multicenter trial.
Association of TERT promoter mutations with telomerase expression in melanoma.
Attenuation of telomerase activity does not increase sensitivity of human melanoma cells to anticancer agents.
AZT on telomerase activity and cell proliferation in HS 839.T melanoma cells.
Biological activity of the G-quadruplex ligand RHPS4 (3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate) is associated with telomere capping alteration.
CCR7-expressing B16 melanoma cells downregulate interferon-?-mediated inflammation and increase lymphangiogenesis in the tumor microenvironment.
Cell-killing by paclitaxel in a metastatic murine melanoma cell line is mediated by extensive telomere erosion with no decrease in telomerase activity.
Chromosomal imbalances in primary and metastatic melanomas: over-representation of essential telomerase genes.
Classifying melanoma by TERT promoter mutational status.
Clinical significance of PCR-positive mRNA markers in peripheral blood and regional nodes of malignant melanoma patients. Melanoma Cooperative Group.
Clinicopathological relevance of NF?B1/p50 nuclear immunoreactivity and its relationship with the inflammatory environment of uveal melanoma.
Coexistence of TERT promoter and BRAF mutations in cutaneous melanoma is associated with more clinicopathological features of aggressiveness.
Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial.
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands.
Detection of circulating neoplastic cells by reverse-transcriptase polymerase chain reaction in malignant melanoma: association with clinical stage and prognosis.
Detection of mRNA of Telomerase Protein in Benign Naevi and Melanomas Using RNAscope.
Detection of RNA-dependent DNA polymerase activity in the Xiphophorus melanoma system.
Detection of telomerase activity and correlation with mitotic and apoptotic indices, Ki-67 and expression of cyclins D1 and A in cutaneous melanoma.
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Detection of telomerase RNA in the plasma of patients with breast cancer, malignant melanoma or thyroid cancer.
Different effects of interferon-alpha on melanoma cell lines: a study on telomerase reverse transcriptase, telomerase activity and apoptosis.
Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma, and glioma cells in culture.
Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro.
Effects of nano-encapsulated curcumin-chrysin on telomerase, MMPs and TIMPs gene expression in mouse B16F10 melanoma tumour model.
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase.
Evaluation of combined h-TERT, bcl-2, and caspases 3 and 8 expression in cutaneous malignant melanoma based on tissue microarrays and computerized image analysis.
Evaluation of MDR1, LRP, MRP, and topoisomerase IIalpha gene mRNA transcripts before and after interferon-alpha, and correlation with the mRNA expression level of the telomerase subunits hTERT and TEP1 in five unselected human melanoma cell lines.
Evaluation of telomerase activity in cutaneous melanocytic proliferations.
Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma.
Expression of cancer testis antigens in head and neck squamous cell carcinomas.
Expression of cell cycle and apoptosis regulatory proteins and telomerase in melanocitic lesions.
Expression of cytokine genes in a patient with conjunctival melanoma compared with other pigment cells.
Expression of differentiation melanoma-associated antigen genes is associated with favorable disease outcome in advanced-stage melanomas.
Familial melanoma and multiple primary melanoma.
Frequency of telomerase reverse transcripter promoter mutations in desmoplastic melanoma subtypes: analyses of 76 cases.
Frequency of TERT Promoter Mutations in Prostate Cancer.
Genes and pathways downstream of telomerase in melanoma metastasis.
Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network.
Genomic and Transcriptomic Analysis Reveals Incremental Disruption of Key Signaling Pathways during Melanoma Evolution.
HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features.
Highly Aggressive Metastatic Melanoma Cells Unable to Maintain Telomere Length.
Highly recurrent TERT promoter mutations in human melanoma.
hTERT expression in melanocytic lesions: an immunohistochemical study on paraffin-embedded tissue.
Human telomerase and alpha-methylacyl-coenzyme A racemase in prostatic carcinoma. A comparative immunohistochemical study.
Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.
Human telomerase RNA component expression in Spitz nevi, common melanocytic nevi, and malignant melanomas.
Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures.
IL-10 expression by primary tumor cells correlates with melanoma progression from radial to vertical growth phase and development of metastatic competence.
Impact of molecular staging methods in primary melanoma: reverse-transcriptase polymerase chain reaction (RT-PCR) of ultrasound-guided aspirate of the sentinel node does not improve diagnostic accuracy, but RT-PCR of peripheral blood does predict survival.
In silico analysis of human Telomerase Reverse Transcriptase (hTERT) gene: identification of a distant homolog of Melanoma Antigen Family Gene (MAGE).
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
In-situ hybridization-based quantification of hTR: a possible biomarker in malignant melanoma.
Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas.
Increased expression of apoptotic markers in melanoma.
Increased thymidylate synthase gene expression in metastatic melanoma.
Indomethacin and telomerase activity in tumor growth retardation.
Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases.
Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma.
Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells.
Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells.
Inhibition of telomerase activity by a hammerhead ribozyme targeting the RNA component of telomerase in human melanoma cells.
Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells.
Inhibition of telomerase activity of melanoma cells in vitro by antisense oligonucleotides.
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
Inhibition on telomerase activity and cytotoxic effects by cisplatin in cultured human choroidal melanoma cells.
Lack of prognostic importance of reverse-transcriptase polymerase chain reaction detection of circulating messenger RNA in patients with melanoma.
Malignancy without immortality? Evidence for cellular immortalization as a late event in melanoma progression.
MAPK Pathway and TERT Promoter Gene Mutation Pattern and Its Prognostic Value in Melanoma Patients: A Retrospective Study of 2,793 Cases.
Melanoma antigen-encoding gene family member A1-6 and hTERT in the detection of circulating tumor cells following CD45(-) depletion and RNA extraction.
Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF.
Melanoma, nevogenesis, and stem cell biology.
Melanomas of unknown primary frequently harbor TERT-promoter mutations.
Migration and metalloproteinases determine the invasive potential of mouse melanoma cells, but not melanin and telomerase.
Modulating telomerase activity in tumor patients by targeting dyskerin binding site for hTR.
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.
Molecular analyses of sentinel lymph nodes: an open question.
Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas.
Murine and human melanomas containing a high molecular weight RNA associated with an RNA-instructed DNA polymerase.
Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma.
Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma.
Naturally occurring Telomerase-specific CD4 T cell Immunity in Melanoma.
Oncornavirus-like particles in human skin cancers.
Particle-associated RNA-directed DNA polymerase and 70S RNA in the hamster melanoma A Mel 3.
Pathology and genomics of pediatric melanoma: A critical reexamination and new insights.
Pathology of the sentinel lymph node in melanoma.
Possible diagnostic role of telomerase activity evaluation in the differential diagnosis between spitz naevi and cutaneous malignant melanoma.
Possible regulation of telomerase activity by transcription and alternative splicing of telomerase reverse transcriptase in human melanoma.
Preclinical studies on detection of circulating melanoma cells in patients: telomerase as a recognition marker of malignancy.
Prevalence and implications of TERT promoter mutation in uveal and conjunctival melanoma and in benign and premalignant conjunctival melanocytic lesions.
Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma.
Prognostic value of tyrosinase reverse-transcriptase polymerase chain reaction in metastatic melanoma.
Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma.
Quantification of hTERT splice variants in melanoma by SYBR green real-time polymerase chain reaction indicates a negative regulatory role for the beta deletion variant.
Rapid purification of an RNA tumor virus and proteins by high-performance steric exclusion chromatography on porous glass bead columns.
Reconstitution of hTERT restores tumorigenicity in melanoma-derived c-Myc low-expressing clones.
Recurrent TERT promoter mutations in urothelial carcinoma and potential clinical applications.
Screening of inhibitors of human telomerase reverse transcriptase in a cultured malignant melanoma cell line.
Sentinel node biopsy in melanoma.
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach.
Spontaneous regression of cutaneous melanoma in sinclair swine is associated with defective telomerase activity and extensive telomere erosion.
Suppressing tumor growth of nasopharyngeal carcinoma by hTERTC27 polypeptide delivered through adeno-associated virus plus adenovirus vector cocktail.
Synthesis, biological evaluation, drug-likeness, and in silico screening of novel benzylidene-hydrazone analogues as small molecule anticancer agents.
T helper 1 cytokine mRNA is increased in spontaneously regressing primary melanomas.
Telomerase activity and expression of apoptosis and anti-apoptosis regulators in the progression pathway of human melanoma.
Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents.
Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis.
Telomerase activity in melanocytic lesions: A potential marker of tumor biology.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase activity in prognostic histopathologic features of melanoma.
Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi.
Telomerase Expression in a Series of Melanocytic Neoplasms.
Telomerase expression in uveal melanoma.
Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients.
Telomerase promoter mutations in cancer: an emerging molecular biomarker?
Telomerase reverse transcriptase (TERT) promoter mutations in Korean melanoma patients.
Telomerase reverse transcriptase promoter mutations and solar elastosis in cutaneous melanoma.
Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma.
Telomerase Reverse Transcriptase Protein Expression Is More Frequent in Acral Lentiginous Melanoma Than in Other Types of Cutaneous Melanoma.
Telomerase. A target for anticancer therapy.
Telomere dysfunction increases cisplatin and ecteinascidin-743 sensitivity of melanoma cells.
Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk.
Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma.
TERT copy gain predicts the outcome of high-dose interferon ?-2b therapy in acral melanoma.
TERT promoter mutation in resectable hepatocellular carcinomas: a strong association with hepatitis C infection and absence of hepatitis B infection.
TERT promoter mutation is uncommon in acral lentiginous melanoma.
TERT promoter mutation subtypes and survival in stage I and II melanoma patients.
TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors.
TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas.
TERT Promoter Mutations Differently Correlate with the Clinical Outcome of MAPK Inhibitor-Treated Melanoma Patients.
TERT promoter mutations in periocular carcinomas: implications of ultraviolet light in pathogenesis.
TERT promoter mutations in sinonasal malignant melanoma: a study of 49 cases.
TERT promoter mutations in telomere biology.
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
The higher incidence of squamous cell carcinoma in renal transplant recipients is associated with increased telomere lengths.
The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells.
The relationship between telomerase activity and proliferation in cutaneous melanoma.
The TERT copy number gain is sensitive to telomerase inhibitors in human melanoma.
The use of molecular profiling of early colorectal cancer to predict micrometastases.
Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes.
Truncated TERT mRNA transfected dendritic cells evoke TERT specific antitumor response in vivo.
Tumor mRNA-transfected dendritic cells stimulate the generation of CTL that recognize neuroblastoma-associated antigens and kill tumor cells: immunotherapeutic implications.
Tumour microdissemination and survival in metastatic melanoma.
Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.
Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity.
Update in genetic susceptibility in melanoma.
Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.
What is the role of sequential reverse-transcriptase polymerase chain reaction analysis of melanoma-specific mRNA in the peripheral blood of melanoma patients?
[Correlation between the biological behavior and invasion potential in three mouse melanoma cell lines]
[Effects of cisplatin on telomerase activity of human choroidal melanoma cells]
[Significance of human telomerase RNA expression in situ in malignant melanoma]
[Telomerase activity in uveal melanomas]
Melanoma, Experimental
Transgene expression of alpha tumor necrosis factor with mutations D142N and A144R under control of human telomerase reverse transcriptase promoter eradicates well-established tumors and induces long-term antitumor immunity.
Memory Disorders
Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.
Meningioma
A genetic strategy to overcome the senescence of primary meningioma cell cultures.
Adjunctive markers for classification and diagnosis of central nervous system tumors: results of a multi-center neuropathological survey in Korea.
Alterations of INK4a(p16-p14ARF)/INK4b(p15) expression and telomerase activation in meningioma progression.
Clinical and diffusion parameters may noninvasively predict TERT promoter mutation status in grade II meningiomas.
Correlation of clinical features and telomerase activity in human gliomas.
Differential telomerase expression and telomere length in primary intracranial tumors.
Differential telomerase expression in human primary intracranial tumors.
Efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from TERT.
Establishment of a benign meningioma cell line by hTERT-mediated immortalization.
Establishment of an in vivo meningioma model with human telomerase reverse transcriptase.
Expression of somatostatin receptor mRNA in human meningiomas and their implication in in vitro antiproliferative activity.
hTERT promoter methylation in meningiomas and central nervous hemangiopericytomas.
Immunohistochemical and molecular study of radiation-induced multiple meningiomas with pleural and pulmonary metastasis.
Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas.
Implication of telomerase activity and alternations of telomere length in the histologic characteristics of intracranial meningiomas.
Influence of Human Telomerase Reverse Transcriptase Mutation on the Aggressiveness and Recurrence in Meningiomas.
Intratumoral heterogeneity and
Letter: Parasagittal/Falcine Tumor Location Strongly Predicts Human Telomerase Reverse Transcriptase Promoter Mutations in High-Grade Meningiomas.
Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk.
Meningioma: an update.
Meningiomas, dicentric chromosomes, gliomas, and telomerase activity.
Molecular genetics of meningiomas: from basic research to potential clinical applications.
Pathology and genetics of meningiomas.
PCNA, Ki-67 and hTERT in residual benign meningiomas.
Plasma miR-185 as a predictive biomarker for prognosis of malignant glioma.
Prognostic value of allelic losses and telomerase activity in meningiomas.
Prognostic value of proliferation index and expression of the RNA component of human telomerase (hTR) in papillary meningiomas.
Progression of astrocytomas and meningiomas: an evaluation in vitro.
Rapid, quantitative nonisotopic assay for telomerase activity in human tumors.
Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and expression of telomerase reverse transcriptase correlated with cell proliferation in meningiomas and malignant brain tumors in vivo.
Telomerase activity and expression of the telomerase catalytic subunit, hTERT, in meningioma progression.
Telomerase activity and hTERT protein expression in meningiomas: an analysis in vivo versus in vitro.
Telomerase activity in 144 brain tumours.
Telomerase Activity in Human Brain Tumors: Astrocytoma and Meningioma.
Telomerase activity in ordinary meningiomas predicts poor outcome.
Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review.
Telomerase expression in intracranial tumours: prognostic potential for malignant gliomas and meningiomas.
Telomerase in intracranial meningiomas.
TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.
TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma.
The hTERT-protein and Ki-67 labelling index in recurrent and non-recurrent meningiomas.
The significant role of telomerase activity in human brain tumors.
Meningitis
Clinical characteristics of enteroviral meningitis without pleocytosis in children: a retrospective single center observational study in the Republic of Korea.
Menkes Kinky Hair Syndrome
Identification of three novel mutations in the MNK gene in three unrelated Japanese patients with classical Menkes disease.
Novel mutation of L718X in the ATP7A gene in a Japanese patient with classical Menkes disease, and four novel polymorphisms in the Japanese population.
Pigmentary disorders of the eyes and skin.
Mental Retardation, X-Linked
Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas.
Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors.
Mesothelioma
Expression profile of telomerase subunits in human pleural mesothelioma.
Human telomerase and alpha-methylacyl-coenzyme A racemase in prostatic carcinoma. A comparative immunohistochemical study.
Mechanistic in vitro studies: What they have told us about carcinogenic properties of elongated mineral particles (EMPs).
Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity.
miR-380-5p-mediated repression of TEP1 and TSPYL5 interferes with telomerase activity and favours the emergence of an "ALT-like" phenotype in diffuse malignant peritoneal mesothelioma cells.
Multiple mechanisms of telomere maintenance exist and differentially affect clinical outcome in diffuse malignant peritoneal mesothelioma.
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma.
SV40 infection induces telomerase activity in human mesothelial cells.
Telomerase activity analyzed with trap in situ provides additional information in effusions remaining equivocal after immunocytochemistry and hyaluronan analysis.
Telomerase activity in human pleural mesothelioma.
Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup.
Mesothelioma, Malignant
Expression of telomerase reverse transcriptase (TERT) in malignant mesotheliomas.
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma.
Pathology of malignant mesothelioma.
SV40 infection induces telomerase activity in human mesothelial cells.
Telomerase activity in human pleural mesothelioma.
Telomerase activity in pleural malignant mesotheliomas.
Metabolic Diseases
Telomerase: a key player in the pathogenesis of non-alcoholic fatty liver disease?
Metabolic Syndrome
Cell aging in relation to stress arousal and cardiovascular disease risk factors.
Connection between telomerase activity in PBMC and markers of inflammation and endothelial dysfunction in patients with metabolic syndrome.
Effect of Sechium edule var. nigrum spinosum (Chayote) on Telomerase Levels and Antioxidant Capacity in Older Adults with Metabolic Syndrome.
HIV infection, antiretroviral therapy and cardiovascular risk.
Novel Neuroendocrine and Metabolic Mechanism Provides the Patented Platform for Important Rejuvenation Therapies: Targeted Therapy of Telomere Attrition and Lifestyle Changes of Telomerase Activity with the Timing of Neuron-Specific Imidazole-Containing Dipeptide-Dominant Pharmaconutrition Provision.
TA-65, A Telomerase Activator, Improves Cardiovascular Markers in Patients with Metabolic Syndrome.
The impact of depression and anxiety treatment on biological aging and metabolic stress: study protocol of the MOod treatment with antidepressants or running (MOTAR) study.
Mitochondrial Diseases
Mitochondrial disorders among infants exposed to HIV and antiretroviral therapy.
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
Mitochondrial Myopathies
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Mixed Connective Tissue Disease
Telomerase activity in peripheral blood mononuclear cells of systemic connective tissue diseases.
Mixed Tumor, Malignant
Cellular proliferative and telomerase activity in canine mammary gland tumors.
Monoclonal Gammopathy of Undetermined Significance
Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.
Expression Profile of Telomere-associated Genes in Multiple Myeloma.
Telomerase activity in plasma cell dyscrasias.
Mouth Neoplasms
Clinical significance of telomere length and associated proteins in oral cancer.
Clinical usefulness of telomerase assay for the detection of lymph node metastasis in patients with oral malignancy.
Cloning and expression of hamster telomerase catalytic subunit cDNA.
Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo.
Diagnostic and prognostic relevance of expression of human telomerase subunits in oral cancer.
Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer.
Electrochemical telomerase assay for screening for oral cancer.
Elevated expression of hTERT is associated with dysplastic cell transformation during human oral carcinogenesis in situ.
Expression of human telomerase reverse transcriptase protein in oral epithelial dysplasia and oral squamous cell carcinoma: An immunohistochemical study.
Expression of telomerase RNA in oesophageal and oral cancer.
Immunohistochemical detection of human telomerase reverse transcriptase in oral cancer and pre-cancer.
Immunohistochemical expression of human telomerase reverse transcriptase in oral cancer and precancer: A case-control study.
Lack of correlation of betel nut chewing, tobacco smoking, and alcohol consumption with telomerase activity and the severity of oral cancer.
Oral cancer diagnosis via a ferrocenylnaphthalene diimide-based electrochemical telomerase assay.
Prognostic Implications of DNA Repair, Ploidy and Telomerase in the Malignant Transformation Risk Assessment of Leukoplakia.
Quantification of telomerase activity in normal oral mucosal tissue and oral squamous cell carcinoma.
Replicative senescence of normal human oral keratinocytes is associated with the loss of telomerase activity without shortening of telomeres.
Saliva as a tool for oral cancer diagnosis and prognosis.
Senescing oral dysplasias are not immortalized by ectopic expression of hTERT alone without other molecular changes, such as loss of INK4A and/or retinoic acid receptor-beta: but p53 mutations are not necessarily required.
Telomerase activity in oral cancer.
Telomerase activity in the occurrence and progression of oral squamous cell carcinoma.
Telomerase and oral cancer.
Telomerase hTR and hTRT gene expression in oral precancerous lesions and squamous cell carcinomas.
Telomerase: An exploration toward the end of cancer.
Telomere attrition and telomerase activity are associated with GSTM1 polymorphism in oral cancer.
Telomeres, telomerase and oral cancer (Review).
Upstream stimulatory factor (USF) as a transcriptional suppressor of human telomerase reverse transcriptase (hTERT) in oral cancer cells.
[Identification of telomerase activity in the experimental carcinogenesis of oral cavity]
[Telomerase activity in rat tongue carcinogenesis]
[Telomerase hTRT mRNA expression in oral squamous cell carcinogenesis]
Mucocutaneous Lymph Node Syndrome
Absence of significant RNA-dependent DNA polymerase activity in lymphocytes from patients with Kawasaki syndrome.
Association between a novel human coronavirus and Kawasaki disease.
Multiple Myeloma
Clinical significance of telomerase activity in multiple myeloma.
Cytokines modulate telomerase activity in a human multiple myeloma cell line.
Determination of telomerase activity and telomere length.
Differential downregulation of telomerase activity by bortezomib in multiple myeloma cells-multiple regulatory pathways in vitro and ex vivo.
Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.
Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.
Expression of interleukin-11 receptor in CD38-positive cells from patients with multiple myeloma.
Expression Profile of Telomere-associated Genes in Multiple Myeloma.
Identifying the biomarker potential of telomerase activity and shelterin complex molecule, telomeric repeat binding factor 2 (TERF2), in multiple myeloma.
Novel combination of tanshinone I and lenalidomide induces chemo-sensitivity in myeloma cells by modulating telomerase activity and expression of shelterin complex and its associated molecules.
Prognostic relevance of telomere length and telomerase reverse transcriptase variant (rs2242652) on the multiple myeloma patients.
Research for the influence of telomerase inhibitors on myeloma cell and therapy.
Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length.
Telomerase activity in myeloma cells is closely related to cell cycle status, but not to apoptotic signals induced by interferon-alpha.
Telomerase activity in plasma cell dyscrasias.
Telomerase and telomere length in multiple myeloma: correlations with disease heterogeneity, cytogenetic status, and overall survival.
Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma.
Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma.
Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms.
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.
Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes.
The Effects of Proteasome Inhibitors on Telomerase Activity and Regulation in Multiple Myeloma Cells.
[A study of cellular telomerase activity in different stages of multiple myeloma cells]
[Effect of arsenic trioxide on telomerase and telomerase reverse transcriptase in KM3 cell line]
Mumps
Laboratory testing and phylogenetic analysis during a mumps outbreak in Ontario, Canada.
Two successive outbreaks of mumps in Nova Scotia among vaccinated adolescents and young adults.
Muscle Cramp
Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease.
Muscular Atrophy, Spinal
SMN and coilin negatively regulate dyskerin association with telomerase RNA.
Muscular Diseases
A case of lactic acidosis caused by stavudine in an AIDS patient.
Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs.
Muscle-fiber transdifferentiation in an experimental model of respiratory chain myopathy.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Skeletal myopathy associated with nucleoside reverse transcriptase inhibitor therapy: potential benefit of coenzyme Q10 therapy.
Muscular Dystrophies
Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies.
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides.
Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a duchenne myoblast cell line with long-term genotypic and phenotypic stability.
Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice.
Musculoskeletal Diseases
The role of telomeres in musculoskeletal diseases.
Mycosis Fungoides
Detection of telomerase activity in patients with mycosis fungoides.
Shortened telomere length is demonstrated in T-cell subsets together with a pronounced increased telomerase activity in CD4 positive T cells from blood of patients with mycosis fungoides and parapsoriasis.
Myelodysplastic Syndromes
A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome.
Characterization of In Vitro G-Quadruplex Formation of Imetelstat Telomerase Inhibitor.
Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia.
Dysregulation of Telomere Lengths and Telomerase Activity in Myelodysplastic Syndrome.
Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies.
Elevated telomerase activity in essential thrombocythemia with extreme thrombocytosis.
Familial myelodysplastic syndromes - a review of the literature.
Fanconi Anemia germline variants as susceptibility factors in aplastic anemia, MDS and AML.
Human telomerase reverse transcriptase expression in a CD34-positive hematopoietic progenitor of myelodysplastic syndrome and acute myelogenous leukemia.
Imbalance between apoptosis and telomerase activity in myelodysplastic syndromes: possible role in ineffective hemopoiesis.
Increase of telomerase activity and hTERT expression in myelodysplastic syndromes.
Lack of mutations of the human telomerase RNA gene (hTERC) in myelodysplastic syndrome.
Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.
Low frequency of telomerase RNA mutations among children with aplastic anemia or myelodysplastic syndrome.
MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells.
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome.
Naive T-cells in myelodysplastic syndrome display intrinsic human telomerase reverse transcriptase (hTERT) deficiency.
Telomerase activity in myelodysplastic syndrome.
Telomerase activity in myelodysplastic syndromes.
Telomerase activity in normal leukocytes and in hematologic malignancies.
Telomerase gene screening and telomere overhang detection in Chinese patients with myelodysplastic syndrome.
Telomerase, hTERT and splice variants in patients with myelodysplastic syndromes.
Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging.
Telomere dysfunction and hematologic disorders.
Telomeres in health and disease.
[Alterations of telomerase activity and apoptosis induced by 2-methoxyestradiol in human myelodysplastic syndrome cell line MUTZ-1]
[Analysis of molecular mechanism involved in development of acute myeloid leukemia].
[Expression of human telomerase reverse transcriptase and survivin gene in patients with myelodysplastic syndrome]
[Study of Telomerase Activity in Bone Marrow Cells from Patients with Myelodysplastic Syndromes]
[Telomere, telomerase and cytogenetic changes in myelodysplastic syndromes]
Myelolipoma
Telomerase activity: comparison between fine-needle aspiration and biopsy specimens for the detection of tumor cells.
Myeloproliferative Disorders
Absence of pathogenic mutations of the human telomerase RNA gene (hTERC) in patients with chronic myeloproliferative disorders.
Analysis of platelets from patients with thrombocythemia for reverse transcriptase and virus-like particles.
Quantitation of RNA-dependent platelet DNA polymerase in patients with myeloproliferative disorders.
Trial watch: Telomerase inhibitor shows promise in myeloproliferative disorders.
Myocardial Infarction
Acute myocardial infarction: 'telomerasing' for cardioprotection.
Bioinformatics analysis of key genes and signaling pathways associated with myocardial infarction following telomerase activation.
Class of antiretroviral drugs and the risk of myocardial infarction.
Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.
Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity.
Impact of individual antiretroviral drugs on the risk of myocardial infarction in human immunodeficiency virus-infected patients: a case-control study nested within the French Hospital Database on HIV ANRS cohort CO4.
Incidence of myocardial infarction in randomized clinical trials of protease inhibitor-based antiretroviral therapy: an analysis of four different protease inhibitors.
Switching from abacavir to tenofovir disoproxil fumarate is associated with rises in soluble glycoprotein VI, suggesting changes in platelet-collagen interactions.
Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury.
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.
Telomerase Is Essential for Zebrafish Heart Regeneration.
Telomerase limits damage after heart attack.
Telomeres and Telomerase in Cardiovascular Diseases.
Telomeres as Therapeutic Targets in Heart Disease.
TERT assists GDF11 to rejuvenate senescent VEGFR2+/CD133+ cells in elderly patients with myocardial infarction.
The association between dietary quality indices and serum telomerase activity in patient candidates for CABG.
Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration.
Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients.
Myoma
Absence of the JAZF1/SUZ12 chimeric transcript in the immortalized non-neoplastic endometrial stromal cell line T HESCs.
Immunohistochemical localization of telomerase in myomas and in uterine myometrium.
Telomerase activity in gynecological tumors.
Myopathies, Nemaline
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Myositis
Autoantibodies targeting telomere-associated proteins in systemic sclerosis.
Severe myositis on commencement of efavirenz, abacavir and lamivudine, in the absence of lactic acidosis or classical abacavir hypersensitivity.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Myositis Ossificans
Telomerase activity in benign bone tumors and tumor-like lesions.
Myotonic Dystrophy
Reliable and versatile immortal muscle cell models from healthy and myotonic dystrophy type 1 primary human myoblasts.
Nasal Polyps
Evaluation of telomerase activity in nasal polyps.
Increased eotaxin-mRNA expression in non-atopic and atopic nasal polyps: comparison to RANTES and MCP-3 expression.
Overexpression of hepatocyte growth factor and its receptor c-Met in nasal polyps.
Telomerase in nasal polyps.
Nasopharyngeal Carcinoma
A functional tandem-repeats polymorphism in the downstream of TERT is associated with the risk of nasopharyngeal carcinoma in Chinese population.
A G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells.
Antisense oligonucleotides targeting human telomerase mRNA increases the radiosensitivity of nasopharyngeal carcinoma cells.
Cancer stem cell-like characteristics and telomerase activity of the nasopharyngeal carcinoma radioresistant cell line CNE-2R.
Diagnostic usefulness of telomerase activity in nasopharyngeal carcinoma.
Differentiation of human nasopharyngeal carcinoma xenografts and repression of telomerase activity induced by arsenic trioxide.
Effect of RNA interference targeting human telomerase reverse transcriptase on telomerase and its related protein expression in nasopharyngeal carcinoma cells.
Effect of trichosanthin on apoptosis and telomerase activity of nasopharyngeal carcinomas in nude mice.
Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells.
Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma.
Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture.
Inhibition of telomerase activity in cancer cells using short hairpin RNA expression vectors.
Insufficient PINX1 expression stimulates telomerase activation by direct inhibition of EBV LMP1-NF-?B axis during nasopharyngeal carcinoma development.
Joint quantitative measurement of hTERT mRNA in both peripheral blood and circulating tumor cells of patients with nasopharyngeal carcinoma and its clinical significance.
Latent membrane protein 1 encoded by Epstein-Barr virus induces telomerase activity via p16INK4A/Rb/E2F1 and JNK signaling pathways.
Mechanisms of cell immortalization mediated by EB viral activation of telomerase in nasopharyngeal carcinoma.
Nuclear translocation of telomerase reverse transcriptase is a critical process in lymphatic metastasis of nasopharyngeal carcinoma.
Phyllanthus urinaria increases apoptosis and reduces telomerase activity in human nasopharyngeal carcinoma cells.
PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells.
Pro-apoptotic and anti-proliferative effects of 3,3'-diindolylmethane in nasopharyngeal carcinoma cells via downregulation of telomerase activity.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Regulation of telomerase activity by gamma-radiation in nasopharyngeal carcinoma cells.
Subtelomeric demethylation deregulated hTERT expression, telomerase activity, and telomere length in four nasopharyngeal carcinoma cell lines.
Targeting EBV-LMP1 DNAzyme enhances radiosensitivity of nasopharyngeal carcinoma cells by inhibiting telomerase activity.
Telomerase activation by Epstein-Barr virus latent membrane protein 1 is associated with c-Myc expression in human nasopharyngeal epithelial cells.
Telomerase activation in nasopharyngeal carcinomas.
Telomerase assay and nested polymerase chain reaction from nasopharyngeal swabs for early noninvasive detection of nasopharyngeal carcinoma.
Telomerase is regulated by protein kinase C-zeta in human nasopharyngeal cancer cells.
The Pinx1 Gene Downregulates Telomerase and Inhibits Proliferation of CD133+ Cancer Stem Cells Isolated from a Nasopharyngeal Carcinoma Cell Line by Regulating Trfs and Mad1/C-Myc/p53 Pathways.
[Construction and screening of a ribozyme targeting telomerase RNA and effects of telomerase ribozyme on proliferation and apoptosis of CNE-2Z cells]
[Down-regulation of telomerase and its RNA and apoptosis in the HNE1 cell line of nasopharyngeal carcinoma induced by retinoid]
[Effects of telomerase sense and antisense oligodeoxynucleotides on growth and differentiation of nasopharyngeal carcinoma cells]
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
[Expression of telomerase subunits and its relationship with telomerase activity in nasopharyngeal carcinoma]
[Influence and mechanism of PinX1 gene on the chemotherapy sensitivity of nasopharyngeal carcinoma cells in response to Cisplatin].
[Profile of telomerase and telomerase RNA expression in nasopharyngeal carcinogenesis of rats induced by N, N'dinitrosopiperazine (DNP)]
[Quantitative detection of plasma level of human telomerase reverse transcriptase mRNA in patients with nasopharyngeal carcinoma].
[Study on the relationship between TK gene regulated by enhanced suicide gene vector and telomerase activity in nasopharyngeal carcinoma cells]
[The effect of shRNA targeting hTERT on telomerase and the expression of PCNA and Caspase-3 in nasopharyngeal carcinoma cells]
[The inhibitory role of zhongjiefeng extracts, on apoptosis and telomerase activity of nasopharyngeal carcinoma cell line exnograf in nude mice]
[The study on the role of telomerase activity in human nasopharyngeal carcinoma]
[Tumor-targeted human telomerase reverse transcriptase promoter/tk gene therapy against human nasopharyngeal carcinoma cells in vitro.]
Nasopharyngeal Neoplasms
Cdc42/Rac1 participates in the control of telomerase activity in human nasopharyngeal cancer cells.
Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture.
Pin2 telomeric repeat factor 1-interacting telomerase inhibitor 1 (PinX1) inhibits nasopharyngeal cancer cell stemness: implication for cancer progression and therapeutic targeting.
Telomerase activity is frequently found in metaplastic and malignant human nasopharyngeal tissues.
Telomerase is regulated by protein kinase C-zeta in human nasopharyngeal cancer cells.
Nasopharyngitis
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
Neoplasm Metastasis
A second chance for telomerase reverse transcriptase in anticancer immunotherapy.
A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women.
Aberrant telomerase expression in the endometrium of infertile women with deep endometriosis.
Aggressive differentiated thyroid cancer with multiple metastases and NRAS and TERT promoter mutations: A case report.
An anti-apoptosis gene, survivin and telomerase expression in gastric cancer.
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
Antidepressants, prostaglandins and the prevention and treatment of cancer.
Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA.
Association between circulating tumor cells and prognosis in patients with stage III melanoma with sentinel lymph node metastasis in a phase III international multicenter trial.
Basic mechanisms involved in the anti-cancer effects of melatonin.
Biodegradable Black Phosphorus Nanosheets Mediate Specific Delivery of hTERT siRNA for Synergistic Cancer Therapy.
Cascaded Electrochemiluminescence Signal Amplifier for the Detection of Telomerase Activity from Tumor Cells and Tissues.
Catalytic subunit of human telomerase reverse transcriptase is an independent predictor of survival in patients undergoing curative resection of hepatic colorectal metastases: a multicenter analysis.
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.
Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast.
Clinical evaluation of biologically targeted drugs: obstacles and opportunities.
Clinical implications of telomerase activity in resected hepatocellular carcinoma.
Clinical significance of telomerase activity in gastric carcinoma and peritoneal dissemination.
Clinical significance of telomerase activity in peripheral blood of patients with esophageal squamous cell carcinoma.
Clinical significance of telomerase activity in peritoneal lavage fluid from patients with gastric cancer and its relationship with cellular proliferation.
Clinical usefulness of telomerase assay for the detection of lymph node metastasis in patients with oral malignancy.
Clinical utility of telomerase for the diagnosis of malignant well-differentiated endocrine tumours.
Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer.
Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers.
Correlation between telomerase activity and DNA ploidy in gastric cancer.
Detection of cancer cells in mesenteric vein and peripheral vessels by measuring telomerase activity in patients with colorectal cancer.
Detection of telomerase activity in saliva from oral squamous cell carcinoma patients.
Diagnostic value of urinary molecular markers in bladder cancer.
Differential telomerase expression in human primary intracranial tumors.
Does the presence of circulating tumor cells in the venous drainage of curative colorectal cancer resections determine prognosis? A meta-analysis.
Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.
Elevation of telomerase activity positively correlates to poor prognosis of patients with non-small cell lung cancer.
Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion.
Essential roles of telomerase reverse transcriptase hTERT in cancer stemness and metastasis.
Evaluation of telomerase activity in cutaneous melanocytic proliferations.
Evaluation of telomerase in the development and progression of colon cancer.
Evaluation of telomerase mRNA (hTERT) in colon cancer.
Ex vivo expanded telomerase-specific T cells are effective in an orthotopic mouse model for pancreatic adenocarcinoma.
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.
Expression and suppression of human telomerase RNA.
Expression of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in gastric adenocarcinomas.
Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.
Fundamental insights into the interaction between telomerase/TERT and intracellular signaling pathways.
Gastric cancer with high telomerase activity shows rapid development and invasiveness.
Genes and pathways downstream of telomerase in melanoma metastasis.
GeneSearch™ BLN Assay could replace frozen section and touch imprint cytology for intra-operative assessment of breast sentinel lymph nodes.
Genetic alterations in anaplastic thyroid carcinoma and targeted therapies.
High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.
HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
hTERT mediates gastric cancer metastasis partially through the indirect targeting of ITGB1 by microRNA-29a.
HTERT mRNA expression correlates with matrix metalloproteinase-1 and vascular endothelial growth factor expression in human breast cancer: a correlative study using RT-PCR.
hTERT promoter mutations in chondrosarcomas associate with progression and disease-related mortality.
hTERT promotes the invasion of telomerase-negative tumor cells in vitro.
hTERT-based therapy: a universal anticancer approach (Review).
Human high molecular weight-melanoma-associated antigen: utility for detection of metastatic melanoma in sentinel lymph nodes.
Human telomerase reverse transcriptase (hTERT) and Ki-67 are better predictors of survival than established clinical indicators in patients undergoing curative hepatic resection for colorectal metastases.
Identification and functional characterization of nuclear mortalin in human carcinogenesis.
IgG1-iS18 impedes the adhesive and invasive potential of early and late stage malignant melanoma cells.
Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma: tumor size and lymph node status remain the most important prognostic features.
Immunohistochemical and molecular study of radiation-induced multiple meningiomas with pleural and pulmonary metastasis.
Immunohistochemical detection of telomerase reverse transcriptase (TERT) protein in benign and malignant tumor cells of the breast.
Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance.
Implications of telomerase reverse transcriptase in tumor metastasis.
In situ Analysis of Cancer Cells Based on DNA Signal Amplification and DNA Nanodevices.
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
Increased telomerase activities in human pancreatic duct adenocarcinomas.
Inhibition of telomerase activity by NME2: impact on metastasis suppression?
KI-67 AND hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma.
Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation.
Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity.
Knockdown of LRP/LR induces apoptosis in pancreatic cancer and neuroblastoma cells through activation of caspases.
Lack of prognostic importance of reverse-transcriptase polymerase chain reaction detection of circulating messenger RNA in patients with melanoma.
Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients.
Long non-coding RNAs: novel prognostic biomarkers for liver metastases in patients with early stage colorectal cancer.
Lymph node metastases, not human telomerase reverse transcriptase or p53 proteins, as the strongest prognostic factor for survival in early stage cervical cancer.
Lymphatic mapping and sentinel node analysis in colon cancer.
Mangiferin and Cancer: Mechanisms of Action.
Marek's disease: Genetic regulation of gallid herpesvirus 2 infection and latency.
Means to the ends: The role of telomeres and telomere processing machinery in metastasis.
Metastases suppressor NME2 associates with telomere ends and telomerase and reduces telomerase activity within cells.
Metastatic-prone telomerase reverse transcriptase (TERT) promoter and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutated tall cell variant of papillary thyroid carcinoma arising in ectopic thyroid tissue: A case report.
Missing association between telomerase activity and clinicopathological features in patients with early stage carcinoma of the cervix.
Molecular aspects of invasion and metastasis of stomach cancer.
Molecular Detection of Circulating Tumor Cells in the Peripheral Blood of Patients with Colorectal Cancer Using RT-PCR: Significance of the Prediction of Postoperative Metastasis.
Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance of the prediction of postoperative metastasis.
Molecular staging of lung cancer: real-time polymerase chain reaction estimation of lymph node micrometastatic tumor cell burden in stage I non-small cell lung cancer--preliminary results of Cancer and Leukemia Group B Trial 9761.
Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.
Noncoding telomeric repeat-containing RNA inhibits the progression of hepatocellular carcinoma by regulating telomerase-mediated telomere length.
Novel biological agents for the treatment of hormone-refractory prostate cancer (HRPC).
Nuclear translocation of telomerase reverse transcriptase is a critical process in lymphatic metastasis of nasopharyngeal carcinoma.
Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases.
Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro.
Part I. Telomerase levels in human metastatic brain tumors show four-fold logarithmic variability but no correlation with tumor type or interval to patient demise.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Pathophysiology of ocular surface squamous neoplasia.
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone.
Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness.
Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis.
Prognostic value of TERT promoter mutations in conjunctival melanomas in addition to clinicopathological features.
Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma.
Prostate-specific antigen (protein and mRNA) analysis in the differential diagnosis and staging of prostate cancer.
Proteomic studies coupled with RNAi methodologies can shed further light on the downstream effects of telomerase in glioma.
Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression.
Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma.
Ratiometric Fluorescent Biosensor for Visual Discrimination of Cancer Cells with Different Telomerase Expression Levels.
Recent developments in breast cancer therapy.
Relationship between microvessel density and telomerase activity in hepatocellular carcinoma.
Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma.
Renal cell carcinoma (RCC) and telomerase activity: relationship to stage.
Screening and preliminary validation of miRNAs with the regulation of hTERT in colorectal cancer.
Shifting from clinical to biologic indicators of prognosis after resection of hepatic colorectal metastases.
siRNA - Mediated LRP/LR knock-down reduces cellular viability of malignant melanoma cells through the activation of apoptotic caspases.
Suppression of telomerase, reexpression of KAI1, and abrogation of tumorigenicity by nerve growth factor in prostate cancer cell lines.
Surgical significance of telomerase activity in noncancerous liver tissue from patients with hepatocellular carcinoma.
Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists.
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Telomerase activity analysis of esophageal carcinoma using microdissection-TRAP assay.
Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.
Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma.
Telomerase activity and human telomerase reverse transcriptase expression in colorectal carcinoma.
Telomerase activity and human telomerase reverse transcriptase mRNA expression are correlated with clinical aggressiveness in soft tissue tumors.
Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes.
Telomerase activity and lymphovascular invasion in breast cancer.
Telomerase activity and metastasis: expansion of cells having higher telomerase activity within culture lines and tumor tissues.
Telomerase activity and serum levels of p53 protein as prognostic factors of survival in patients with advanced non-small cell lung cancer.
Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients.
Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma.
Telomerase activity in brain and leptomeningeal metastases.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in gastric cancer.
Telomerase activity in gynecological tumors.
Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.
Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome.
Telomerase activity in pancreatic endocrine tumours: a potential marker for malignancy.
Telomerase activity in primary prostate cancer.
Telomerase activity in soft-tissue and bone sarcomas.
Telomerase activity in the human breast.
Telomerase activity in transthoracic fine-needle biopsy aspirates from non-small cell lung cancer as prognostic factor of patients' survival.
Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.
Telomerase activity of blood samples and recurrence of colorectal cancer.
Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion.
Telomerase activity significantly correlates with cell differentiation, proliferation and lymph node metastasis in colorectal carcinomas.
Telomerase activity: a prevalent marker of malignant human prostate tissue.
Telomerase as a diagnostic and predictive marker in colorectal carcinoma.
Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study.
Telomerase expression in human breast cancer with and without lymph node metastases.
Telomerase inhibition and cancer: might platinum based drugs have a future as anti-telomerase pharmacological approach?
Telomerase inhibition regulates EMT mechanism in breast cancer stem cells.
Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases.
Telomerase reverse transcriptase mediates EMT through NF-?B signaling in tongue squamous cell carcinoma.
Telomerase reverse transcriptase methylation predicts lymph node metastasis and prognosis in patients with gastric cancer.
Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.
Telomerase-A molecular marker for cervical cancer screening.
Telomerase: going beyond the ends.
Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.
Telomere length, telomerase activity and telomerase RNA expression during mouse mammary tumor progression.
Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk.
The association between telomerase, histopathological parameters, and KI-67 expression in breast cancer.
The clinical significance of PINX1 expression in papillary thyroid carcinoma.
The influence of reactivation of the telomerase in tumour tissue on the prognosis of squamous cell carcinomas in the head and neck.
The Pinx1 Gene Downregulates Telomerase and Inhibits Proliferation of CD133+ Cancer Stem Cells Isolated from a Nasopharyngeal Carcinoma Cell Line by Regulating Trfs and Mad1/C-Myc/p53 Pathways.
The role of Nuclear Factor-kappa B signaling in human cervical cancer.
Therapeutic strategies for targeting telomerase in cancer.
Therapeutic targets of cancer drugs: Modulation by melatonin.
Thyroid carcinomas that express telomerase follow a more aggressive clinical course in children and adolescents.
Tumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach.
Tumor interstitial fluid and gastric cancer metastasis: an experimental study to verify the hypothesis of "tumor-phlegm microenvironment".
Upregulated long non-coding RNA BC032469 enhances carcinogenesis and metastasis of esophageal squamous cell carcinoma through regulating hTERT expression.
Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development.
[Clinical significance of telomerase activity in lung cancer.]
[Contemporary study of strengthening body resistance and archaeus herbs on malignant tumor]
[Detection of telomerase activity in laryngeal carcinoma and the association between telomerase activity and lymphatic metastasis]
[Detection of telomerase activity in the blood of patients with lung cancer.]
[Establishment of a pulmonary metastasis model of melanoma with stably expressed hTERT/Luc].
[Expression of telomerase activity in human lung cancer.]
[Metformin--new treatment strategies for gynecologic neoplasms].
[Prognostic and diagnostic value of telomerase in the head and neck cancer]
[Progress on prevention and treatment of Chinese medicine to molecular mechanism of liver cancer]
[Quantitative assay of telomerase activity in head and neck squamous cell carcinoma]
[Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck]
[Significance of human telomerase RNA expression in situ in malignant melanoma]
[Significance of telomerase expression in diagnosis and treatment of breast tumor]
[Study on telomerase activity and its clinical value in human non small cell lung cancer]
[Telomerase activity in cervical cancer and its precursor lesion]
[Telomerase activity in gastric cancer and premalignant lesions: determination and its clinical significance]
[Telomerase activity in infiltration ductal carcinoma of breast]
[Telomerase activity in liver cancer and the adjacent tissue]
[The experimental study on telomerase activity and expression of p53 and c-myc genes in tongue cancer]
[The role of telomerase for pancreatic carcinogenesis in human and hamster]
[The study on the role of telomerase activity in human nasopharyngeal carcinoma]
Neoplasm Micrometastasis
Clinical significance of telomerase activity in peritoneal lavage fluid from patients with gastric cancer and its relationship with cellular proliferation.
Clinical usefulness of telomerase assay for the detection of lymph node metastasis in patients with oral malignancy.
Comparative detection of lymph node micrometastases of stage II colorectal cancer by reverse transcriptase polymerase chain reaction and immunohistochemistry.
Detection and clinical significance of bone marrow micrometastases in patients undergoing liver transplantation for hepatocellular carcinoma.
Detection of breast cancer micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Comparison between MUC1 mRNA and keratin 19 mRNA amplification.
Detection of hTERT mRNA in peripheral blood and its implication for diagnosis of early stage postoperative endometrial cancer micrometastasis.
Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients.
Lymph node, peritoneal and bone marrow micrometastases in gastric cancer: Their clinical significance.
Molecular analyses of sentinel lymph nodes: an open question.
Molecular quantification and mapping of lymph-node micrometastases in cervical cancer.
Molecular staging of lung cancer: real-time polymerase chain reaction estimation of lymph node micrometastatic tumor cell burden in stage I non-small cell lung cancer--preliminary results of Cancer and Leukemia Group B Trial 9761.
Quantification of colorectal cancer micrometastases in lymph nodes by nested and real-time reverse transcriptase-PCR analysis for carcinoembryonic antigen.
Quantitative real-time polymerase chain reaction detection of lymph node lung cancer micrometastasis using carcinoembryonic antigen marker.
Telomerase activity in peripheral blood for diagnosis of hepatoma.
[Clinical significance of molecular biological detection of micrometastases in gastric carcinoma]
[Detecting micrometastases in sentinel lymph nodes]
[Detection of breast cancer micrometastases in lymph nodes by amplification of keratin 19 mRNA with reverse-transcriptase polymerase chain reaction]
[Significance of detection of micrometastases in regional lymph nodes in cancer patients using RT-PCR]
Neoplasm, Residual
A t(16;21)(p11;q22) in Acute Myeloid Leukemia (AML) Resulting in Fusion of the FUS/TLS and ERG Genes: A Review of the Literature.
Assessment of Minimal Residual Disease in Standard-Risk AML.
Association between telomerase activity and outcome in patients with nonmetastatic Ewing family of tumors.
Competitive CBFbeta/MYH11 reverse-transcriptase polymerase chain reaction for quantitative assessment of minimal residual disease during postremission therapy in acute myeloid leukemia with inversion(16): a pilot study.
Cytogenetic and molecular monitoring of residual disease in chronic myeloid leukaemia.
Early assessment of minimal residual disease identifies patients at very high relapse risk in NPM-ALK-positive anaplastic large-cell lymphoma.
Ewing family tumors: potential prognostic value of reverse-transcriptase polymerase chain reaction detection of minimal residual disease in peripheral blood samples.
Long-term efficacy of low-dose all-trans retinoic acid plus minimal chemotherapy induction followed by the addition of intravenous arsenic trioxide post-remission therapy in newly diagnosed acute promyelocytic leukaemia.
Maspin and mammaglobin genes are specific markers for RT-PCR detection of minimal residual disease in patients with breast cancer.
Minimal residual disease detection in acute promyelocytic leukemia by reverse-transcriptase PCR: evaluation of PML-RAR alpha and RAR alpha-PML assessment in patients who ultimately relapse.
Telomerase activity in breast cancer in Western India (Gujarat).
Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour?
Telomerase in relation to expression of p53, c-Myc and estrogen receptor in ovarian tumours.
Telomeres and telomerase in hematologic neoplasia.
[Allogenic bone marrow transplantation after reduced intensity conditioning regimens in therapy of patients with hemoblastoses]
[Prognostic factors of infiltrating bladder tumors]
Neoplasms
'Infectious web'.
1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498.
1,3,4-Oxadiazoles: An emerging scaffold to target growth factors, enzymes and kinases as anticancer agents.
1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase.
12E2: a cloned murine dermal cell with features of dermal dendrocytes and capacity to produce pathologic changes resembling early Kaposi's sarcoma.
17?-Ethynyl-androst-5-ene-3?,7?,17?-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease.
2-5A antisense therapy directed against human telomerase RNA inhibits telomerase activity and induces apoptosis without telomere impairment in cervical cancer cells.
3rd Geneva aging workshop 2002: cancer, apoptosis and aging.
4-1BB-based Isolation and Expansion of CD8+ T Cells Specific for Self-Tumor and Non-Self-Tumor Antigens for Adoptive T-cell Therapy.
4-Hydroxynonenal inhibits telomerase activity and hTERT expression in human leukemic cell lines.
5,6-trans-16-ene-vitamin D3: a new class of potent inhibitors of proliferation of prostate, breast, and myeloid leukemic cells.
5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions.
5-Bromodeoxyuridine induces senescence-like phenomena in mammalian cells regardless of cell type or species.
6-Dithio-2'-deoxyguanosine analogs induce reactive oxygen species-mediated tumor cell apoptosis via bi-targeting thioredoxin 1 and telomerase.
9th Seah Cheng Siang Memorial Lecture: gastric cancer--where are we now?
In vitro Reconstitution of the Active T. castaneum Telomerase.
?-Catenin Directly Regulates Tert.
A 4:1 stoichiometric binding and stabilization of mitoxantrone-parallel stranded G-quadruplex complex established by spectroscopy techniques.
A 6-mer photocontrolled oligonucleotide as an effective telomerase inhibitor.
A brief history of the mortality and immortality of cultured cells.
A cancer detection platform which measures telomerase activity from live circulating tumor cells captured on a microfilter.
A case of dedifferentiated solitary fibrous tumor of the thoracic cavity.
A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin.
A Cisplatin Derivative Tetra-Pt(bpy) as an Oncotherapeutic Agent for Targeting ALT Cancer.
A Clinical Overview of Telomerase-Associated Aberrancies in Follicular Thyroid Tumors as Diagnostic and Prognostic Markers: Tert Alert!
A combination of semiquantitative telomerase assay and in-cell telomerase activity measurement using exfoliated urothelial cells for the detection of urothelial neoplasia.
A combination of the telomerase inhibitor, BIBR1532, and paclitaxel synergistically inhibit cell proliferation in breast cancer cell lines.
A Combinatory Strategy for Detection of Live CTCs Using Microfiltration and a New Telomerase-Selective Adenovirus.
A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase.
A comparative study of telomerase activity and malignant phenotype in multistage carcinogenesis of esophageal epithelial cells induced by human papillomavirus.
A comparison between PLGA-PEG and NIPAAm-MAA nanocarriers in curcumin delivery for hTERT silencing in lung cancer cell line.
A comparison between stem cells from the adult human brain and from brain tumors.
A comparison of the inhibitory effect of nano-encapsulated helenalin and free helenalin on telomerase gene expression in the breast cancer cell line, by real-time PCR.
A comprehensive review on anticancer mechanisms of the main carotenoid of saffron, crocin.
A conformational switch-based fluorescent biosensor for homogeneous detection of telomerase activity.
A convenient synthesis of novel thiazolidin-4-one-linked pseudodisaccharides by tandem Staudinger/aza-Wittig/cyclization and their biological evaluation.
A critical role for telomeres in suppressing and facilitating carcinogenesis.
A cyano analogue of boswellic acid induces crosstalk between p53/PUMA/Bax and telomerase that stages the human papillomavirus type 18 positive HeLa cells to apoptotic death.
A cytometric assay for ultrasensitive and robust detection of human telomerase RNA based on toehold strand displacement.
A diagnostic evaluation of serum human telomerase reverse transcriptase mRNA as a novel tumor marker for gynecologic malignancies.
A DNA telomerase vaccine for canine cancer immunotherapy.
A dual-colored ratiometric-fluorescent oligonucleotide probe for the detection of human telomerase RNA in cell extracts.
A facile DNA/RNA nanoflower for sensitive imaging of telomerase RNA in living cells based on "zipper lock-and-key" strategy.
A facile graphene oxide-based fluorescent nanosensor for the in situ "turn-on" detection of telomerase activity.
A First-in-Human Phase I Study of INVAC-1, an Optimized Human Telomerase DNA Vaccine in Patients with Advanced Solid Tumors.
A Fluorescent Anti-Cancer Agent, 3,6-bis(1-methyl-4-vinylpyridinium) Carbazole Diiodide, Stains G-Quadruplexes in Cells and Inhibits Tumor Growth.
A functional variant of tandem repeats in human telomerase gene was associated with survival of patients with early stages of non-small cell lung cancer.
A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells.
A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia.
A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity.
A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants.
A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro.
A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells.
A high-throughput assay for a human telomerase protein-human telomerase RNA interaction.
A highly selective telomerase inhibitor limiting human cancer cell proliferation.
A highly sensitive and facile graphene oxide-based nucleic acid probe: Label-free detection of telomerase activity in cancer patient's urine using AIEgens.
A Highly Sensitive Catalytic Hairpin Assembly-Based Dynamic Light-Scattering Biosensors for Telomerase Detection in Bladder Cancer Diagnosis.
A homeopathic nosode, Hepatitis C 30 demonstrates anticancer effect against liver cancer cells in vitro by modulating telomerase and topoisomerase II activities as also by promoting apoptosis via intrinsic mitochondrial pathway.
A human breast cancer model for the study of telomerase inhibitors based on a new biotinylated-primer extension assay.
A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT.
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.
A label-free electrochemical biosensor for ultra-sensitively detecting telomerase activity based on the enhanced catalytic currents of acetaminophen catalyzed by Au nanorods.
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation.
A microfluidic platform to synthesize a G-quadruplex binding ligand.
A molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study.
A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-dimensional in vitro tumor spheroids as a screening model.
A multi-recycling amplification-based sensor for label-free and highly sensitive detection of telomerase from cancer cells.
A multi-target protein of hTERTR-FAM96A presents significant anticancer potent in the treatment of hepatocellular carcinoma.
A Narrative Review of Genetic Alterations in Primary Thyroid Epithelial Cancer.
A network of genetic events sufficient to convert normal human cells to a tumorigenic state.
A new fluorescence/PET probe for targeting intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated IgM.
A new multiparameter assay to assess HPV 16/18, viral load and physical status together with gain of telomerase genes in HPV-related cancers.
A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.
A non-isotopic method for the detection of telomerase activity in tumour tissues: TRAP-silver staining assay.
A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT.
A novel antiangiogenic effect for telomerase-specific virotherapy through host immune system.
A novel apoptotic mechanism of genetically engineered adenovirus-mediated tumour-specific p53 overexpression through E1A-dependent p21 and MDM2 suppression.
A novel carbazole derivative, BMVC: a potential antitumor agent and fluorescence marker of cancer cells.
A novel conditionally replicative adenovirus vector targeting telomerase-positive tumor cells.
A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-?B inactivation in colorectal cancer cells.
A novel electrochemical biosensor for sensitive detection of telomerase activity based on structure-switching DNA.
A novel embryonic stem cell line derived from the common marmoset monkey (Callithrix jacchus) exhibiting germ cell-like characteristics.
A novel homodimeric lactose-binding lectin from the edible split gill medicinal mushroom Schizophyllum commune.
A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.
A novel human cancer culture model for the study of prostate cancer.
A novel human cell culture model for the study of familial prostate cancer.
A Novel Liquid Biopsy Strategy to Detect Small Amounts of Cancer Cells Using Cancer-Specific Replication Adenoviruses.
A novel magnetic bead-based assay with high sensitivity and selectivity for analysis of telomerase in exfoliated cells from patients with bladder and colon cancer.
A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.
A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation.
A novel molecular therapy using bioengineered adenovirus for human gastrointestinal cancer.
A novel oHSV-1 targeting telomerase reverse transcriptase-positive cancer cells via tumor-specific promoters regulating the expression of ICP4.
A novel oncolytic adenovirus expressing Escherichia coli cytosine deaminase exhibits potent antitumor effect on human solid tumors.
A novel oncolytic adenovirus targeting to telomerase activity in tumor cells with potent.
A novel peptide-nucleotide dual vaccine of human telomerase reverse transcriptase induces a potent cytotoxic T-cell response in vivo.
A novel platinum compound inhibits telomerase activity in vitro and reduces telomere length in a human hepatoma cell line.
A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias.
A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells.
A novel telomerase template antagonist (GRN163) as a potential anticancer agent.
A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter.
A novel telomere elongation in an adriamycin-resistant stomach cancer cell line with decreased telomerase activity.
A novel telomere structure in a human alternative lengthening of telomeres cell line.
A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues.
A novel treatment of human malignant gliomas in vitro and in vivo: FADD gene transfer under the control of the human telomerase reverse transcriptase gene promoter.
A novel truncated form of HMGA2 in tumors of the ovaries.
A novel tumor-specific gene therapy for bladder cancer.
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.
A PCR-free colorimetric strategy for visualized assay of telomerase activity.
A PCR-free fluorescence strategy for detecting telomerase activity via double amplification strategy.
A PCR-free voltammetric telomerase activity assay using a substrate primer on a gold electrode and DNA-triggered capture of gold nanoparticles.
A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters.
A phase I study of telomerase-specific replication competent oncolytic adenovirus (telomelysin) for various solid tumors.
A Polyadenylation-Dependent 3' End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA.
A positive feedback loop between Wnt/?-catenin signaling and hTERT regulates the cancer stem cell-like traits in radioresistant nasopharyngeal carcinoma cells.
A potential bat adenovirus-based oncolytic virus targeting canine cancers.
A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).
A prospective evaluation of the diagnostic and potential prognostic utility of urinary human telomerase reverse transcriptase mRNA in patients with bladder cancer.
A quantitative assay of telomerase activity.
A quantitative method to measure telomerase activity by bioluminescence connected with telomeric repeat amplification protocol.
A rapid biosensor chip assay for measuring of telomerase activity using surface plasmon resonance.
A rapid, useful and quantitative method to measure telomerase activity by hybridization protection assay connected with a telomeric repeat amplification protocol.
A Rare Variant P507L in TPP1 Interrupts TPP1-TIN2 Interaction, Influences Telomere Length, and Confers Colorectal Cancer Risk in Chinese Population.
A resonance Rayleigh scattering sensor for sensitive differentiation of telomere DNA length and monitoring special motifs (G-quadruplex and i-motif) based on the Ag nanoclusters and NAND logic gate responding to chemical input signals.
A Review of Molecular Mechanisms in the Development of Hepatocellular Carcinoma by Aflatoxin and Hepatitis B and C Viruses.
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas.
A robust fluorescent probe for detection of telomerase activity in vitro and imaging in living cells via telomerase-triggering primer extension to desorb DNA from graphene oxide.
A robust probe for lighting up intracellular telomerase via primer extension to open a nicked molecular beacon.
A Role for Human DNA Polymerase ? in Alternative Lengthening of Telomeres.
A scalable and reproducible preparation for the antitumor protein TLC, a human-derived telomerase inhibitor.
A second chance for telomerase reverse transcriptase in anticancer immunotherapy.
A second essential function of the Est1-binding arm of yeast telomerase RNA.
A selective cyclooxygenase-2 inhibitor suppresses tumor growth in nude mouse xenografted with human head and neck squamous carcinoma cells.
A sensitive direct human telomerase activity assay.
A sensitive fluorescence strategy for telomerase detection in cancer cells based on T7 exonuclease-assisted target recycling amplification.
A sensitive, label-free electrochemical detection of telomerase activity without modification or immobilization.
A simple "mix-and-detection" method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions.
A simple and sensitive fluorescence method for detection of telomerase activity using fusion protein bouquets.
A simple two-gene prognostic model for adenocarcinoma of the lung.
A simple, fast, label-free colorimetric method for detection of telomerase activity in urine by using hemin-graphene conjugates.
A single quantum dot-based biosensor for telomerase assay.
A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands.
A single-molecule view of telomerase regulation at telomeres.
A Smart DNA Tweezer for Detection of Human Telomerase Activity.
A Static Magnetic Field Inhibits the Migration and Telomerase Function of Mouse Breast Cancer Cells.
A study on telomerase activity and prognosis in breast cancer.
A survey of telomerase activity in human cancer.
A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women.
A Telomerase Responsive DNA-icosahedron for Precise Delivery of Platinum-nanodrug to Cisplatin-resistance Cancer.
A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer.
A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes.
A telomerase-responsive nanoprobe with theranostic properties in tumor cells.
A Telomerase-Specific Doxorubicin-Releasing Molecular Beacon for Cancer Theranostics.
A telomere-independent senescence mechanism is the sole barrier to Syrian hamster cell immortalization.
A TLR9 agonist enhances therapeutic effects of telomerase genetic vaccine.
A transfectant mosaic xenograft model for evaluation of targeted radiotherapy in combination with gene therapy in vivo.
A translational bridge to cancer immunotherapy: exploiting costimulation and target antigens for active and passive T cell immunotherapy.
A Triad of Telomerase, Androgen Receptor and Early Growth Response 1 in Prostate Cancer Cells.
A triple helix within a pseudoknot is a conserved and essential element of telomerase RNA.
A triple-amplification strategy for sensitive detection of telomerase at the single-cell level.
A tumor-derived population (SCCOHT-1) as cellular model for a small cell ovarian carcinoma of the hypercalcemic type.
A unified alternative telomere-lengthening pathway in yeast survivor cells.
A Unique Immunofluorescence Protocol to Detect Protein Expression in Vascular Tissues: Tacking a Long Standing Pathological Hitch.
A vaccine targeting telomerase enhances survival of dogs affected by B-cell lymphoma.
A yeast chemical genetic screen identifies inhibitors of human telomerase.
AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice.
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
Abacavir induces the transcriptional activity of YY1 and other oncogenic transcription factors in gastric cancer cells.
Aberrant methylation of the TERT promoter in esophageal squamous cell carcinoma.
Abnormal expression of hepatomas and circulating telomerase and its clinical values.
Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability.
Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis.
Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma.
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.
Absence of correlation between telomerase activity and hepatic neoplasia in B6C3F1 mice.
Absence of telomerase activity and telemorase catalytic subunit mRNA in melanocyte cultures.
Absence of telomerase activity in malignant bone tumors and soft-tissue sarcomas.
Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.
Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment.
Accuracy of telomerase in cervical lesions: a systematic review.
Accurate Identification and Early Diagnosis of Osteosarcoma through CRISPR-Cas12a-Based Average Telomerase Activity Detection.
Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c-Myc expression.
Acidified bile acids increase hTERT expression via c-myc activation in human gastric cancer cells.
Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.
Actions of human telomerase beyond telomeres.
Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone.
Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse.
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Activation of telomerase by HPVs.
Activation of telomerase by seminal plasma in malignant and normal cervical epithelial cells.
Activation of telomerase in a human tumor.
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells.
Activation of telomerase is induced by a natural antigen in allergen-specific memory T lymphocytes in bronchial asthma.
Activation of telomerase rna gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.
Activation of the hTERT expression in squamous cell cervical carcinoma is not associated with gene amplification.
Activin inhibits telomerase activity in cancer.
Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients.
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways.
Activity of telomerase in ovarian cancer cells. Clinical implications.
Activity of the human telomerase catalytic subunit (hTERT) gene promoter could be increased by the SV40 enhancer.
Activity of the upstream component of tandem TERT/survivin promoters depends on features of the downstream component.
Activity of Wnt/PCP Regulation Pathway Classifies Patients of Low-Grade Glioma Into Molecularly Distinct Subgroups With Prognostic Difference.
ACV-TP-T, a thymidine analogue pro-drug activated by telomerase, reduces pancreatic tumor growth in mice.
Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner.
ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells.
Adding to the ends: what makes telomerase processive and how important is it?
Adeno-associated virus type 2 as an oncogenic virus in human hepatocellular carcinoma.
Adenosquamous carcinoma of the pancreas: preoperative diagnosis and molecular alterations.
Adenoviral mediated transduction of adenoid cystic carcinoma by human TRAIL gene driven with hTERT tumor specific promoter induces apoptosis.
Adenovirus-mediated and tumor-specific transgene expression of the sodium-iodide symporter from the human telomerase reverse transcriptase promoter enhances killing of lung cancer cell line in vitro.
Adenovirus-mediated HSV-TK gene therapy using the human telomerase promoter induced apoptosis of small cell lung cancer cell line.
Adenovirus-mediated suicide gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter induced apoptosis of ovarian cancer cell line.
Adenovirus-mediated suicide SCLC gene therapy using the increased activity of the hTERT promoter by the MMRE and SV40 enhancer.
Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner.
Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging.
Advances in optical assays for detecting telomerase activity.
Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).
Advances in the detection of telomerase activity using isothermal amplification.
Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.
Advances on the regulation of telomerase.
Advantages of assaying telomerase activity in ascites for diagnosis of digestive tract malignancies.
Affinity and selectivity of G4 ligands measured by FRET.
Affinity chromatography of RNA-dependent DNA polymerase from RNA tumor viruses on a solid phase immunoadsorbent.
Age-related Deterioration of Hematopoietic Stem Cells.
Ageing and cancer: the telomere and telomerase connection.
Ageing mechanisms: the role of telomere loss.
Agents that target telomerase and telomeres.
Aggressive differentiated thyroid cancer with multiple metastases and NRAS and TERT promoter mutations: A case report.
Aggressive Treatment in Glioblastoma: What Determines the Survival of Patients?
Aging and cancer: are telomeres and telomerase the connection?
Aging of tissue-resident adult stem/progenitor cells and their pathological consequences.
Aging Schwann cells in vitro.
AGO2 promotes telomerase activity and interaction between the telomerase components TERT and TERC.
Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat).
Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma.
ALK-Positive Inflammatory Myofibroblastic Tumor of the Abdomen With Widespread Microscopic Multifocality.
All-atomic simulations on human telomeric G-quadruplex DNA binding with thioflavin T.
All-trans retinoic acid (atra) inhibits telomerase expression of BeWo choriocarcinoma cell (ATCC CCL-98).
Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.
Allele-specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers.
Aloe emodin inhibits telomerase activity in breast cancer cells: transcriptional and enzymological mechanism.
ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition.
ALT neuroblastoma chemoresistance due to telomere dysfunction-induced ATM activation is reversible with ATM inhibitor AZD0156.
ALT Telomeres Get Together with Nuclear Receptors.
ALT-associated PML bodies are present in viable cells and are enriched in cells in the G(2)/M phase of the cell cycle.
ALT-associated promyelocytic leukaemia body (APB) detection as a reproducible tool to assess alternative lengthening of telomere stability in liposarcomas.
ALT: A Multi-Faceted Phenomenon.
Alteration of telomerase activity associated with development and extension of epithelial ovarian cancer.
Alteration of Telomere Length and Subtelomeric Methylation in Human Endothelial Cells under Different Levels of Hypoxia.
Alterations of INK4a(p16-p14ARF)/INK4b(p15) expression and telomerase activation in meningioma progression.
Altered TERT promoter and other genomic regulatory elements: occurrence and impact.
Alternative lengthening of human telomeres is a conservative DNA replication process with features of break-induced replication.
Alternative lengthening of telomeres (ALT) and chromatin: is there a connection?
Alternative Lengthening of Telomeres (ALT) in Tumors and Pluripotent Stem Cells.
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.
Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.
Alternative lengthening of telomeres in hTERT-inhibited laryngeal cancer cells.
Alternative lengthening of telomeres in human cells.
Alternative Lengthening of Telomeres in Human Glioma Stem Cells.
Alternative lengthening of telomeres in human glioma stem cells.
Alternative lengthening of telomeres in mammalian cells.
Alternative lengthening of telomeres in molecular subgroups of paediatric high-grade glioma.
Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies.
Alternative Lengthening of Telomeres in the Budding Yeast Naumovozyma castellii.
Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas.
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors.
Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells.
Alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas.
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.
Alternative lengthening of telomeres, telomerase, and cancer.
Alternative lengthening of telomeres: from molecular mechanisms to therapeutic outlooks.
Alternative lengthening of telomeres: models, mechanisms and implications.
Alternative lengthening of telomeres: remodeling the telomere architecture.
Alternative mechanisms of telomere lengthening: Permissive mutations, DNA repair proteins and tumorigenic progression.
Alternative methods of extracting telomerase activity from human tumor samples.
Alternative paths to telomere elongation.
Alternative pathways for the extension of cellular life span: inactivation of p53/pRb and expression of telomerase.
Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity.
Alternative Splicing of Human Telomerase Reverse Transcriptase (hTERT) and Its Implications in Physiological and Pathological Processes.
Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461.
Alternative splicing of human telomerase reverse transcriptase may not be involved in telomerase regulation during all-trans-retinoic acid-induced HL-60 cell differentiation.
Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers.
Alternative splicing regulation of telomerase: a new paradigm?
Alternative strategy for Alzheimer's disease: stress response triggers.
ALTernative Telomere Maintenance and Cancer.
Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells.
Amarogentin Induces Apoptosis of Liver Cancer Cells via Upregulation of p53 and Downregulation of Human Telomerase Reverse Transcriptase in Mice.
Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives.
Amino-bisphosphonates decrease hTERT gene expression in breast cancer in vitro.
Aminoglycoside Binding to Oxytricha nova Telomeric DNA.
Amplification and novel locations of endogenous mouse mammary tumor virus genomes in mouse T-cell lymphomas.
Amplification of MYCL in Atypical Ewing Tumor. Analysis of Metaphase and Microarray Comparative Genomic Hybridization.
Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels.
Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer.
Amplification of the human epidermal growth factor receptor 2 gene in differentiated thyroid cancer correlates with telomere shortening.
Amplification of the telomerase reverse transcriptase (hTERT) gene in cervical carcinomas.
Amplification of the telomerase RNA component gene in the process of human esophageal carcinogenesis.
Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer.
Amplified chemiluminescence surface detection of DNA and telomerase activity using catalytic nucleic acid labels.
Amplified detection of telomerase activity using electrochemical and quartz crystal microbalance measurements.
Amplified telomerase analysis by using rotating magnetic particles: the rapid and sensitive detection of cancer cells.
An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1.
An all-in-one telomerase assay based on CRISPR-Cas12a trans-cleavage while telomere synthesis.
An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity.
An Alternative HIV-1 Non-Nucleoside Reverse Transcriptase Inhibition Mechanism: Targeting the p51 Subunit.
An anti-apoptosis gene, survivin and telomerase expression in gastric cancer.
An antifungal protein from Bacillus amyloliquefaciens.
An antimutagenic metabolite, streptovaricin C, isolated from Streptomyces sp.
An appraisal of telomerase activity in benign prostatic hyperplasia.
An assay for human telomeric G-quadruplex DNA binding drugs.
An atomistic investigation on the interaction of distamycin A and its derivative with the telomeric G-Quadruplex as anticancer agents by molecular dynamics simulation.
An effective intracellular delivery system of monoclonal antibody for treatment of tumors: erythrocyte membrane-coated self-associated antibody nanoparticles.
An Eimeria acervulina OTU protease exhibits linkage-specific deubiquitinase activity.
An enzyme-free electrochemical biosensor based on well monodisperse Au nanorods for ultra-sensitive detection of telomerase activity.
An evaluation cascade for G-quadruplex telomere targeting agents in human cancer cells.
An Evaluation of the Stemness, Paracrine, and Tumorigenic Characteristics of Highly Expanded, Minimally Passaged Adipose-Derived Stem Cells.
An exonuclease I hydrolysis assay for evaluating G-quadruplex stabilization by small molecules.
An exonuclease III and graphene oxide-aided assay for DNA detection.
An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer.
An in vitro investigation of immunomodulatory properties of Lactobacillus plantarum and L. delbrueckii cells and their extracellular polysaccharides.
An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations.
An introduction to telomeres and telomerase.
An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells.
An oligonucleotide affinity column for RNA-dependent DNA polymerase from RNA tumor viruses.
An oncolytic adenovirus controlled by a modified telomerase promoter is attenuated in telomerase-negative cells, but shows reduced activity in cancer cells.
An oncolytic adenovirus expressing granulocyte macrophage colony-stimulating factor shows improved specificity and efficacy for treating human solid tumors.
An Oncolytic Adenovirus Targeting Transforming Growth Factor ? Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy.
An optimized telomerase-specific lentivirus for optical imaging of tumors.
An RNA-seq-based gene expression profiling of radiation-induced tumorigenic mammary epithelial cells.
An ultra-sensitive colorimetric assay for reliable visual detection of telomerase activity.
An ultrasensitive and point-of-care sensor for the telomerase activity detection.
An Update on Phytochemicals in Molecular Target Therapy of Cancer: Potential Inhibitory Effect on Telomerase Activity.
Analysis of DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis.
Analysis of endogenous and exogenous tumor upregulated promoter expression in canine tumors.
Analysis of hTERT mRNA expression in biliary tract and pancreatic cancer.
Analysis of prognostic factors of acute lymphoblastic leukemia in infants: report on CCG 1953 from the Children's Oncology Group.
Analysis of spontaneous tumor-specific CD4 T cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response.
Analysis of telomerase activity and detection of its catalytic subunit, hTERT.
Analysis of telomerase activity and telomere function in cancer.
Analysis of telomerase activity and telomere length in bone and soft tissue tumors.
Analysis of telomerase activity based on a spired DNA tetrahedron TS primer.
Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors, and invasive carcinomas.
Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage.
Analysis of telomerase by the telomeric hemin/g-quadruplex-controlled aggregation of au nanoparticles in the presence of cysteine.
Analysis of telomeres and telomerase.
Analysis of telomeric repeats and telomerase activity in human colon carcinoma cells with gene amplification.
Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets.
Analysis of two mechanisms of telomere maintenance based on the theory of g-Networks and stochastic automata networks.
Analytical validation of telomerase activity for cancer early detection: TRAP/PCR-CE and hTERT mRNA quantification assay for high-throughput screening of tumor cells.
Ancestral telomere shortening: a countdown that will increase mean life span?
Androgen ablation therapy for prostate carcinoma suppresses the immunoreactive telomerase subunit hTERT.
Aneuploidy and telomere attrition are independent determinants of crisis in SV40-transformed epithelial cells.
Angiogenesis and vascular architecture in pheochromocytomas: distinctive traits in malignant tumors.
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice.
Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders.
Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation.
Anti-apoptotic role of telomerase in pheochromocytoma cells.
Anti-cancer effect of GV1001 for prostate cancer; function as a ligand of GnRHR.
Anti-cancer Immunotherapies Targeting Telomerase.
Anti-Cancer Targeting Telomerase Inhibitors: ?-Rubromycin and Oleic Acid.
Anti-G(D2) antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age.
Anti-hTERT siRNA-loaded nanoparticles block the growth of anaplastic thyroid cancer xenograft.
Anti-inflammatory and anti-oxidative activities of lemon myrtle (Backhousia citriodora) leaf extract.
Anti-inflammatory effects of methanol extract of Patrinia scabiosaefolia in mice with ulcerative colitis.
Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry-Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells.
Anti-Proliferative and Pro-Apoptotic Effects of Short-Term Inhibition of Telomerase In Vivo and in Human Malignant B Cells Xenografted in Zebrafish.
Anti-tumor effect of a dual cancer-specific recombinant adenovirus on ovarian cancer cells.
Anti-tumor effects of an oncolytic adenovirus expressing hemagglutinin-neuraminidase of Newcastle disease virus in vitro and in vivo.
Anti-tumor effects of immunotherapeutic peptide on the treatment of hepatocellular carcinoma with HBc carrier.
Anti-tumor effects of telomelysin for head and neck squamous cell carcinoma.
Anti-tumour effects of a dual cancer-specific oncolytic adenovirus on Breast Cancer Stem cells.
Antiadhesive effects of GRN163L--an oligonucleotide N3'->P5' thio-phosphoramidate targeting telomerase.
Antiangiogenesis gene armed tumor-targeting adenovirus yields multiple antitumor activities in human HCC xenografts in nude mice.
Antibody to the RNA-dependent DNA polymerase of mammalian C-type RNA tumor viruses.
Anticancer DNA vaccine based on human telomerase reverse transcriptase generates a strong and specific T cell immune response.
Anticancer therapy targeting telomeres and telomerase : current status.
Antidepressants, prostaglandins and the prevention and treatment of cancer.
Antigenicity and immunogenicity of peptide analogues of a low affinity peptide of the human telomerase reverse transcriptase tumor antigen.
Antisense epidermal growth factor receptor RNA transfection in human glioblastoma cells down-regulates telomerase activity and telomere length.
Antisense hTERT inhibits thyroid cancer cell growth.
Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro.
Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells.
Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells.
Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells.
Antisense oligonucleotides and all-trans retinoic acid have a synergistic anti-tumor effect on oral squamous cell carcinoma.
Antisense oligonucleotides in cancer: recent advances.
Antisense telomerase induced cell growth inhibition, cell cycle arrest and telomerase activity down-regulation in gastric and colon cancer cells.
Antisense telomerase RNA inhibits the growth of human glioma cells in vitro and in vivo.
Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation.
Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer.
Antitumor activity of an hTERT promoter-regulated tumor-selective oncolytic adenovirus in human hepatocellular carcinoma.
Antitumor effect of a dual cancer-specific oncolytic adenovirus on prostate cancer PC-3 cells.
Antitumor effect of a novel adeno-associated virus vector targeting to telomerase activity in tumor cells.
Antitumor effect of COOH-terminal polypeptide of human TERT is associated with the declined expression of hTERT and NF-?B p65 in HeLa cells.
Antitumor effect of human TRAIL on adenoid cystic carcinoma using magnetic nanoparticle-mediated gene expression.
Antitumor effect of new multiple antigen peptide based on HLA-A0201-restricted CTL epitopes of hTERT.
Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
Antitumor effects of systemically delivered adenovirus harboring trans-splicing ribozyme in intrahepatic colon cancer mouse model.
Antitumor effects of telomelysin in combination with paclitaxel or cisplatin on head and neck squamous cell carcinoma.
Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer.
Antitumor polycyclic acridines. 8.(1) Synthesis and telomerase-inhibitory activity of methylated pentacyclic acridinium salts.
Apoptosis and reduced cell proliferation of HL-60 cell line caused by human telomerase reverse transcriptase inhibition by siRNA.
Apoptosis regulating genes, bcl-2 and bax, and human telomerase reverse transcriptase messenger RNA expression in adrenal tumors: possible diagnostic and prognostic importance.
Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands.
Application of a Y-type-DNA-functionalized nanogold probe featuring specific telomerase recognition and doxorubicin release in cancer cells.
Application of machine learning to large in-vitro databases to identify cancer cell characteristics: telomerase reverse transcriptase (TERT) expression.
Application of telomerase activity for screening of primary lung cancer in broncho-alveolar lavage fluid.
Application of telomerase assay for the screening of cervical lesions.
Applications of telomerase in urologic oncology.
Applications of telomerase research in the fight against cancer.
Applications of the telomerase assay in peritoneal washing fluids.
Approaches for the inhibition of human telomerase based on the use of peptide nucleic acids and hammerhead ribozymes.
Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.
ARID1A loss in cancer: Towards a mechanistic understanding.
ARID1A-SIN3A drives retinoic acid-induced neuroblastoma differentiation by transcriptional repression of TERT.
Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells.
Array comparative genomic hybridization reveals unbalanced gain of the MYCN region in Wilms tumors.
Arsenic inhibition of telomerase transcription leads to genetic instability.
Artificial antigen-presenting cells transduced with telomerase efficiently expand epitope-specific, human leukocyte antigen-restricted cytotoxic T cells.
ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells.
Assays for detection of telomerase activity.
Assays for human telomerase activity: progress and prospects.
Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
Assembly of telomeric chromatin to create ALTernative endings.
Assessing Telomerase Activities in Mammalian Cells Using the Quantitative PCR-Based Telomeric Repeat Amplification Protocol (qTRAP).
Assessing telomere length using surface enhanced Raman scattering.
Assessment and quantification of telomerase enzyme activity.
Assessment Effects of Resveratrol on Human Telomerase Reverse Transcriptase Messenger Ribonucleic Acid Transcript in Human Glioblastoma.
Assessment of Minimal Residual Disease in Standard-Risk AML.
Assessment of telomerase activity in nonsegmental vitiligo tissue: a pilot study.
Assessment of telomerase as drug target in breast cancer.
Assessment of the Tumorigenic Potential of Spontaneously Immortalized and hTERT-Immortalized Cultured Dental Pulp Stem Cells.
Assessment of tumourigenic potential in long-term cryopreserved human adipose-derived stem cells.
Association between circulating tumor cells and prognosis in patients with stage III melanoma with sentinel lymph node metastasis in a phase III international multicenter trial.
Association between functional TERT promoter polymorphism rs2853669 and cervical cancer risk in South Indian women.
Association between rs2853669 in TERT gene and the risk and prognosis of human cancer: a systematic review and meta-analysis.
Association between telomerase activity and basic fibroblast growth factor up-regulation in retinoblastomas.
Association between telomerase activity and outcome in patients with nonmetastatic Ewing family of tumors.
Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis.
Association Between TERT rs2736098 Polymorphisms and Cancer Risk-A Meta-Analysis.
Association between TERT rs2853669 polymorphism and cancer risk: A meta-analysis of 9,157 cases and 11,073 controls.
Association between the telomerase reverse transcriptase (TERT) rs2736098 polymorphism and cancer risk: evidence from a case-control study of non-small-cell lung cancer and a meta-analysis.
Association of cellular apoptosis with anti-tumor effects of the Chinese herbal complex in endocrine-resistant cancer cell line.
Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk.
Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells.
Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma.
Association of p53 gene mutation and telomerase activity in resectable non-small cell lung cancer.
Association of PINX1 but not TEP1 Polymorphisms with Progression to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection.
Association of strong risk of hTERT gene polymorphic variants to malignant glioma and its prognostic implications with respect to different histological types and survival of glioma cases.
Association of telomerase activity with radio- and chemosensitivity of neuroblastomas.
Association of telomerase expression with successful heterotransplantation of lung cancer.
Association of TERT promoter mutations with telomerase expression in melanoma.
Associations among telomerase activity, p53 protein overexpression, and genetic instability in lung cancer.
Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden.
Associations of TERT polymorphisms with hepatocellular carcinoma risk in a Han Chinese population.
ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells.
ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells.
Attenuated expression of DFFB is a hallmark of oligodendrogliomas with 1p-allelic loss.
Attenuation of hyperplasia in lung parenchymal and colonic epithelial cells in DMBA-induced cancer by administering Andrographis paniculata Nees extract using animal model.
Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells.
Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells.
Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells.
Attenuation of telomerase activity does not increase sensitivity of human melanoma cells to anticancer agents.
Augmented telomerase activity, reduced telomere length and the presence of alternative lengthening of telomere in renal cell carcinoma: Plausible predictive and diagnostic markers.
Aurora kinase expression in colorectal adenocarcinoma: correlations with clinicopathological features, p16 expression, and telomerase activity.
Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells.
Autoimmune B-cell lymphopenia after successful adoptive therapy with telomerase-specific T lymphocytes.
Autophagy induction reduces telomerase activity in HeLa cells.
Avocado soybean unsaponifiables (ASU) suppress TNF-alpha, IL-1beta, COX-2, iNOS gene expression, and prostaglandin E2 and nitric oxide production in articular chondrocytes and monocyte/macrophages.
Azacitidine, as a DNMT inhibitor decreases hTERT gene expression and telomerase activity more effective compared with HDAC inhibitor in human Head and neck squamous cell carcinoma cell lines.
Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors.
Azidothymidine induces apoptosis and inhibits cell growth and telomerase activity of human parathyroid cancer cells in culture.
AZT as a telomerase inhibitor.
AZT exerts its antitumoral effect by telomeric and non-telomeric effects in a mammary adenocarcinoma model.
B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-?B.
Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence.
Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis.
Banana lectin: a brief review.
Bax-induction gene therapy of pancreatic cancer.
BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.
Bcl-2 modulates telomerase activity.
Beginning to understand the end of the chromosome.
Behaviour of telomere and telomerase during aging and regeneration in zebrafish.
Benzo[a]pyrene decreases global and gene specific DNA methylation during zebrafish development.
Berberine Inhibits Telomerase Activity and Induces Cell Cycle Arrest and Telomere Erosion in Colorectal Cancer Cell Line, HCT 116.
beta-Lapachone (LAPA) Decreases Cell Viability and Telomerase Activity in Leukemia Cells: Suppression of Telomerase Activity by LAPA.
Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy.
Bidirectional regulation of telomerase activity in a subline derived from human lung adenocarcinoma.
Binding of anticancer drug adriamycin to parallel G-quadruplex DNA [d-(TTAGGGT)]4 comprising human telomeric DNA leads to thermal stabilization: A multiple spectroscopy study.
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation.
Binding properties of avian myeloblastosis virus DNA polymerases to nucleic acid affinity columns.
Binding Studies of G-Quadruplex DNA and Porphyrins: Cu(T4) vs Sterically Friendly Cu(tD4).
Biochemical and electron microscopical evidence for the presence of oncorna viruses in spleen tissue from two patients with haematological malignancies.
Biochemical and immunological characterization of Suncus murinus mammary tumor virus DNA polymerase.
Biodegradable Black Phosphorus Nanosheets Mediate Specific Delivery of hTERT siRNA for Synergistic Cancer Therapy.
Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52
Biological and clinical implications of telomere dysfunction in myeloid malignancies.
Biological and therapeutic implications of multisector sequencing in newly diagnosed glioblastoma.
Biological characteristics of neuroblastoma with partial deletion in the short arm of chromosome 1.
Biological Differential Diagnosis of Follicular Thyroid Tumor and Hürthle Cell Tumor on the Basis of Telomere Length and hTERT Expression.
Biological factors and therapeutic modulation in radiotherapy of head and neck cancer.
Biological significance of PinX1 telomerase inhibitor in esophageal carcinoma treatment.
Biology of ovarian cancer.
Biology of telomeres: importance in etiology of esophageal cancer and as therapeutic target.
Bioluminescent method for detecting telomerase activity.
Biomedical applications of nanoflares: Targeted intracellular fluorescence probes.
Biomolecule-nanoparticle hybrid systems for bioelectronic applications.
Biopsy diagnosis of malignant versus benign liver "nodules": new helpful markers. An update.
Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo.
Bioreducible polymer-delivered siRNA targeting human telomerase reverse transcriptase for human cancer gene therapy.
Biosensor Techniques Used for Determination of Telomerase Activity in Cancer Cells.
Bisphosphonates decrease telomerase activity and hTERT expression in MCF-7 breast cancer cells.
Bladder cancer 2000: molecular markers for the diagnosis of transitional cell carcinoma.
Blockade of telomerase function in various cells.
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo.
Bmi-1 siRNA inhibited ovarian cancer cell line growth and decreased telomerase activity.
Bone morphogenetic protein-7 inhibits telomerase activity, telomere maintenance, and cervical tumor growth.
BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells.
Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels.
Bovine herpesvirus type 1 (BHV-1) up-regulates telomerase activity in MDBK cells.
BRACO19 analog dimers with improved inhibition of telomerase and hPot 1.
BRAF and TERT promoter mutations: clinical application in thyroid cancer.
Brain regions associated with telomerase reverse transcriptase promoter mutations in primary glioblastomas.
Brain-derived Neurotrophic Factor Signaling Pathway: Modulation by Acupuncture in Telomerase Knockout Mice.
Brassiparin, an antifungal peptide from Brassica parachinensis seeds.
BRCA1 inhibition of telomerase activity in cultured cells.
Brca2 abrogation engages with the alternative lengthening of telomeres via break-induced replication.
Breast cancer biomarkers and molecular medicine.
Breast cancer biomarkers and molecular medicine: part II.
Breast Field Cancerization: Isolation and Comparison of Telomerase Expressing Cells in Tumor and Tumor Adjacent, Histologically Normal Breast Tissue.
BRG1, the ATPase subunit of SWI/SNF chromatin remodeling complex, interacts with HDAC2 to modulate telomerase expression in human cancer cells.
BRIT-1 expression and its relationship with PARP-1 and CAF-1/p60 in cutaneous melanoma.
BRIT1 regulates p53 stability and functions as a tumor suppressor in breast cancer.
Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb).
Bronchogenic and alveologenic tumors in mice induced by N-nitrosopiperidine.
BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.
Bufalin Induces Mitochondria-Dependent Apoptosis in Pancreatic and Oral Cancer Cells by Downregulating hTERT Expression via Activation of the JNK/p38 Pathway.
Burkitt's tumors contain particles encapsulating RNA-instructed DNA polymerase and high molecular weight virus-related RNA.
Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells.
Butylidenephthalide Suppresses Human Telomerase Reverse Transcriptase (TERT) in Human Glioblastomas.
Butyrate histone deacetylase inhibitors.
C-terminal p73 isoforms repress transcriptional activity of the human telomerase reverse transcriptase (hTERT) promoter.
C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity.
C. elegans survivors without telomerase.
Campesin, a thermostable antifungal peptide with highly potent antipathogenic activities.
Camptothecin shows better promise than Curcumin in the inhibition of the Human Telomerase: A computational study.
Can Dietary Antioxidants Reduce the Incidence of Brain Tumors?
Can hTERT peptide (540-548) -specific CD8 T cells recognize and kill tumor cells?
Cancer and myeloid clonal evolution in the short telomere syndromes.
Cancer cell dynamics in presence of telomerase inhibitors: analysis of in vitro data.
Cancer Cell Targeting with Mouse TERT-Specific Group I Intron of Tetrahymena thermophila.
Cancer immunotherapy targeting the telomerase reverse transcriptase.
Cancer researchers validate and pursue telomerase.
Cancer spectrum and outcomes in the Mendelian short telomere syndromes.
Cancer stem cell-like characteristics and telomerase activity of the nasopharyngeal carcinoma radioresistant cell line CNE-2R.
Cancer stem cells and telomerase as potential biomarkers in veterinary oncology.
Cancer telomeres and white crows.
Cancer therapy with a CRISPR-assisted telomerase-activating gene expression system.
Cancer treatment by telomerase inhibitors: predictions by a kinetic model.
Cancer vaccination with telomerase peptide GV1001.
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Cancer-selective induction of cytotoxicity by tissue-specific expression of targeted trans-splicing ribozyme.
Cancer-specific induction of adenoviral E1A expression by group I intron-based trans-splicing ribozyme.
Cancer-specific killing by the CD suicide gene using the human telomerase reverse transcriptase promoter.
Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications.
Cancer. Cancer and telomeres--an ALTernative to telomerase.
Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Candidate chromosomal regions for genes involved in activation of alternative lengthening of telomeres in human immortal cell lines.
Canis familiaris telomerase reverse transcriptase undergoes alternative splicing.
Carbon Nanocage/Fe3O4/DNA-Based Magnetically Targeted Intracellular Imaging of Telomerase via Catalyzed Hairpin Assembly and Photodynamic-Photothermal Combination Therapy of Tumor Cells.
Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.
Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers.
Cascaded Electrochemiluminescence Signal Amplifier for the Detection of Telomerase Activity from Tumor Cells and Tissues.
Caspase complex in laryngeal squamous cell carcinoma.
Caspase signalling in neuropathic and inflammatory pain in the rat.
Catalytic assembly of DNA nanostructures on a nanoporous gold array as 3D architectures for label-free telomerase activity sensing.
Catalytic Hairpin Assembly-Assisted Rolling Circle Amplification for High-Sensitive Telomerase Activity Detection.
Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase.
Catechin from Burkea africana Hook. Exhibits in vitro inhibition of human telomerase activity.
Cause-specific telomere factors deregulation in hepatocellular carcinoma.
CCR7-expressing B16 melanoma cells downregulate interferon-?-mediated inflammation and increase lymphangiogenesis in the tumor microenvironment.
CD44 isoform expression in the diffuse neuroendocrine system. II. Benign and malignant tumors.
Cdc42/Rac1 participates in the control of telomerase activity in human nasopharyngeal cancer cells.
CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G 2 phase.
CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
Cell cycle-dependent modulation of telomerase activity in tumor cells.
Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres.
Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: a promising implication of telomerase-dependent targeted cancer gene therapy.
Cell immortality and hallmarks of cancer.
Cell populations can use aneuploidy to survive telomerase insufficiency.
Cell proliferation in the presence of telomerase.
Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation.
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.
Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells.
Cell-Free Circulating Plasma hTERT mRNA Is a Useful Marker for Prostate Cancer Diagnosis and Is Associated with Poor Prognosis Tumor Characteristics.
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.
Cellular delivery is a major obstacle for oligodeoxynucleotide inhibition of telomerase activity.
Cellular distribution of telomerase reverse transcriptase in human hepatocellular carcinoma.
Cellular immortality and cancer: From telomerase to cancer stem cells.
Cellular immortality in brain tumours: An integration of the cancer stem cell paradigm.
Cellular proliferative and telomerase activity in canine mammary gland tumors.
Cellular senescence and cancer.
Cellular senescence and cancer: Focusing on traditional Chinese medicine and natural products.
Centchroman altered the expressions of tumor-related genes through active chromatin modifications in mammary cancer.
Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells.
Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres.
Cerebral granular cell astrocytomas: a Mib-1, bcl-2, and telomerase study.
Cervical intraepithelial neoplasia: Telomerase activity and splice pattern of hTERT mRNA.
Change in number and size of circulating tumor cells with high telomerase activity during treatment of patients with gastric cancer.
Change in telomerase activity during human colorectal carcinogenesis.
Change in telomerase activity of rat organs during growth and aging.
Change of telomerase activity in peripheral blood of patients with head and neck squamous cell carcinoma pre and post curative treatment.
Change of telomerase activity in rectal cancer with chemoradiation therapy.
Changes in biologic characteristics of breast cancer treated with high-intensity focused ultrasound.
Changes in telomerase activity of advanced cancers of oral cavity and oropharynx during radiation therapy: correlation with clinical outcome.
Changes in telomerase activity, expression and splicing in response to differentiation of normal and carcinoma colon cells.
Changes in telomere length distribution in low-dose X-ray-irradiated human umbilical vein endothelial cells.
Changes in telomere lengths in renal cell carcinomas.
Changes in the Expression of Pre-Replicative Complex Genes in hTERT and ALT Pediatric Brain Tumors.
Changes of Telomerase Activity and Proliferation by Inhibition of Reverse Transcriptase Activity in Human Cancer Cell.
Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast.
Characterisation of blood-derived exosomal hTERT mRNA secretion in cancer patients: a potential pan-cancer marker.
Characteristics of the major internal protein and RNA-dependent DNA polymerase of bovine leukaemia virus.
CHARACTERISTICS OF TUMORS THAT DEVELOPED IN MICE AFTER TREATMENT WITH IRRADIATED SYNGENEIC MESENCHYMAL STEM CELLS OF BONE MARROW.
Characterization and antitumor activity of triethylene tetramine, a novel telomerase inhibitor.
Characterization and comparison of telomere length, telomerase and reverse transcriptase activity and gene expression in human mesenchymal stem cells and cancer cells of various origins.
Characterization and function of CREB homologue from Crassostrea ariakensis stimulated by rickettsia-like organism.
Characterization and response to interleukin 1 and tumor necrosis factor of immortalized murine biliary epithelial cells.
Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment.
Characterization of a hTERT sequence containing two antigentic epitopes with high affinity for HLA molecule.
Characterization of a human corneal metalloproteinase inhibitor (TIMP-1).
Characterization of a human telomerase reverse transcriptase sequence containing two antigenic epitopes with high affinity for human leucocyte antigen.
Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.
Characterization of DNA polymerase and RNA associated with A-type particles from murine myeloma cells.
Characterization of genomic alterations and the significance of PI3K/mTOR pathway mutations and tumor mutational burden in non?small cell lung cancer.
Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.
Characterization of human breast cancer epithelial cells (HBCEC) derived from long term cultured biopsies.
Characterization of human telomerase reverse transcriptase promoter methylation and transcription factor binding in differentiated thyroid cancer cell lines.
Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues.
Characterization of potassium binding with human telomeres.
Characterization of primary renal carcinoma cultures.
Characterization of ribosomal frameshifting in HIV-1 gag-pol expression.
Characterization of Telomerase (hTERT) in Solid and Hematopoietic Cancer Cell Lines Reveals Different Expression Patterns.
Characterization of telomeres and telomerase expression in Xiphophorus.
Characterization of the In Vitro Inhibitory Potential of the Oligonucleotide Imetelstat on Human Cytochrome P450 Enzymes with Predictions of In Vivo Drug-Drug Interactions.
Characterization of Trypanosoma cruzi telomerase.
Chemical shift assignments and the secondary structure of the Est3 telomerase subunit in the yeast Hansenula polymorpha.
Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.
Chemopreventive agents induce a senescence-like phenotype in rat mammary tumours.
Chemosensitization of bladder cancer cell lines by human telomerase reverse transcriptase antisense treatment.
Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly.
CHIP promotes hTERT degradation and negatively regulates telomerase activity.
Chiral ruthenium(II) polypyridyl complexes: stabilization of g-quadruplex DNA, inhibition of telomerase activity and cellular uptake.
Cholangiocarcinoma: recent progress. Part 2: molecular pathology and treatment.
Chondrosarcoma is not characterized by detectable telomerase activity.
Chordoma of the skull base: predictors of tumor recurrence.
Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene.
Chromosomal alterations, prognostic factors, and targeted molecular therapies for malignant meningiomas.
Chromosomal disruption and rearrangements during murine sarcoma development converge to stable karyotypic formation kept by telomerase overexpression.
Chromosomal end fusion resulting from telomere erosion increases susceptibility to radiation via multinucleation: Effect of p53.
Chromosome end-to-end associations and telomerase activity during cancer progression in human cells after treatment with alpha-particles simulating radon progeny.
Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells.
Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells.
Circadian telomerase activity and DNA synthesis for timing peptide administration.
Circulating tumor cell microseparator based on lateral magnetophoresis and immunomagnetic nanobeads.
Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: a phase III metastatic castration resistant prostate cancer trial.
Circulating tumor cells are associated with recurrent disease in patients with early stage non-small cell lung cancer treated with stereotactic body radiation therapy.
Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer.
Circulating-Free DNA Analysis in Hepatocellular Carcinoma: A Promising Strategy to Improve Patients' Management and Therapy Outcomes.
Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical trial.
Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer.
Clinical application of human telomerase reverse transcriptase gene expression in thyroid follicular tumors by fine-needle aspirations using in situ hybridization.
Clinical Application of TERT Promoter Mutations in Urothelial Carcinoma.
Clinical applications of telomerase in cancer treatment.
Clinical evaluation of biologically targeted drugs: obstacles and opportunities.
Clinical evaluation of human telomerase catalytic subunit in bladder washings from patients with bladder cancer.
Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma.
Clinical impact of serum transforming growth factor-alpha mRNA as a predictive biomarker for the prognosis of fulminant hepatitis.
Clinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer.
Clinical implications of telomerase activity and inactivation of the tumor suppressor gene p16 (CDKN2A) in head and neck cancer.
Clinical implications of telomerase activity in resected hepatocellular carcinoma.
Clinical implications of telomerase detection.
Clinical implications of telomerase in cancer.
Clinical outcome of patients with various advanced cancer types vaccinated with an optimized cryptic human telomerase reverse transcriptase (TERT) peptide: results of an expanded phase II study.
Clinical outcomes of lung transplant recipients with telomerase mutations.
Clinical relevance of telomerase activity in primary gastric lymphoma.
Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer.
Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease.
Clinical significance and usefulness of quantification of telomerase activity in oral malignant and nonmalignant lesions.
Clinical significance of ABCA2' a possible molecular marker for oligodendrogliomas.
Clinical significance of hTERC and C-Myc genes amplification in a group of Egyptian patients with cancer cervix.
Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer.
Clinical significance of telomerase activity in basal cell carcinomas and in tumour-free surgical margins.
Clinical significance of telomerase activity in biopsy specimens of gastric cancer.
Clinical significance of telomerase activity in gastric carcinoma and peritoneal dissemination.
Clinical significance of telomerase activity in hepatocellular carcinoma.
Clinical significance of telomerase activity in multiple myeloma.
Clinical significance of telomerase activity in peritoneal disseminated cells: gastrointestinal cancers.
Clinical significance of telomerase activity in the non-cancerous epithelial region of oesophageal squamous cell carcinoma.
Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus.
Clinical significance of telomerase genes (hTERC and hTERT) amplification in patients with acute myeloid leukemia.
Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer.
Clinical usefulness of telomerase activation and telomere length in head and neck cancer.
Clinical usefulness of telomerase activity and telomere length in the preoperative diagnosis of gastric and colorectal cancer.
Clinical usefulness of telomerase assay for the detection of lymph node metastasis in patients with oral malignancy.
Clinical usefulness of telomerase for the detection of colon cancer in ulcerative colitis patients.
Clinical utility of telomerase for the diagnosis of malignant well-differentiated endocrine tumours.
Clinical utility of telomerase in cancer.
Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer.
Clinicopathological Analysis of HIF-1alpha and TERT on Survival Outcome in Glioblastoma Patients: A Prospective, Single Institution Study.
Clinicopathological characteristics of TERT promoter mutation and telomere length in hepatocellular carcinoma.
Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: insulin-like growth factor-1 receptor gene expression is a useful predictor of liver metastasis from colorectal cancer.
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Clonal cell populations unresponsive to radiosensitization induced by telomerase inhibition.
Clonal heterogeneity in telomerase activity and telomere length in tumor-derived cell lines.
Cloning and characterization of human and mouse telomerase RNA gene promoter sequences.
Cloning and characterization of the promoter region of human LPTS/PinX1 gene.
Cloning and expression of hamster telomerase catalytic subunit cDNA.
Cloning of hTERT cDNA fragment and application of anti-hTERT monoclonal antibody in mechanism of laryngeal carcinogenesis.
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells.
Cloning of mouse telomerase reverse transcriptase gene promoter and identification of proximal core promoter sequences essential for the expression of transgenes in cancer cells.
Closed chromatin loops at the ends of chromosomes.
Co-expression of interleukin 12 enhances antitumor effects of a novel chimeric promoter-mediated suicide gene therapy in an immunocompetent mouse model.
Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy.
CO-FISH, COD-FISH, ReD-FISH, SKY-FISH.
Co-occurrence of Myeloproliferative Neoplasms and Solid Tumors Is Attributed to a Synergism Between Cytoreductive Therapy and the Common TERT Polymorphism rs2736100.
Coadministration of telomerase genetic vaccine and a novel TLR9 agonist in nonhuman primates.
Coevolution of telomerase activity and body mass in mammals: From mice to beavers.
Coexistence of BRAF V600E and TERT Promoter Mutations in Low-grade Serous Carcinoma of Ovary Recurring as Carcinosarcoma in a Lymph Node: Report of a Case.
Coexistence of two distinct G-quadruplex conformations in the hTERT promoter.
Cognitive performance in survivors of breast cancer and markers of biological aging.
Coilin phosphomutants disrupt Cajal body formation, reduce cell proliferation and produce a distinct coilin degradation product.
Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.
Colonic Diverticula Are Not Associated With Mucosal Inflammation or Chronic Gastrointestinal Symptoms.
Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres.
Combating oxidative stress as a hallmark of cancer and aging: Computational modeling and synthesis of phenylene diamine analogs as potential antioxidant.
Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination based on hTERT and survivin following ASCT for myeloma.
Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.
Combination of CT and telomerase+ circulating tumor cells improves diagnosis of small pulmonary nodules.
Combination of hTERT knockdown and IFN-gamma treatment inhibited angiogenesis and tumor progression in glioblastoma.
Combination of oncolytic adenovirotherapy and Bax gene therapy in human cancer xenografted models. Potential merits and hurdles for combination therapy.
Combination therapy of 2-5A antisense against telomerase RNA and cisplatin for malignant gliomas.
Combination therapy of hTERTR and FAM96A for hepatocellular carcinoma through enhancing apoptosis sensitivity.
Combination treatment with flavonoid morin and telomerase inhibitor MST?312 reduces cancer stem cell traits by targeting STAT3 and telomerase.
Combined analysis of cell growth and apoptosis-regulating proteins in HPVs associated anogenital tumors.
Combined analysis of TMPRSS2-ERG and TERT for improved prognosis of biochemical recurrence in prostate cancer.
Combined assay of CYFRA21-1, telomerase and vascular endothelial growth factor in the detection of bladder transitional cell carcinoma.
Combined Detection of mRNA Expression of Alpha-Fetoprotein in Peripheral Blood and Telomerase Activity of Monocytes in Hepatocellular Carcinoma Patients.
Combined effect of cigarette smoke and mineral fibers on the gene expression of cytokine mRNA.
Combined evaluation of expression of telomerase, survivin, and anti-apoptotic Bcl-2 family members in relation to loss of differentiation and apoptosis in human head and neck cancers.
Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer.
Combined treatment with emodin and a telomerase inhibitor induces significant telomere damage/dysfunction and cell death.
Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial.
Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours.
Comparative functional study of the viral telomerase RNA based on natural mutations.
Comparative genomic hybridization and telomerase activity analysis identify two biologically different groups of 4s neuroblastomas.
Comparative study of ¹?F-FDG-PET/CT imaging and serum hTERT mRNA quantification in cancer diagnosis.
Comparing the Role of the p53 Gene and Telomerase Enzyme in 'Accelerated Aging Due to Cancer': A Literature Review.
Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics.
Comparison of human telomerase reverse transcriptase messenger RNA and telomerase activity as urine markers for diagnosis of bladder carcinoma.
Comparison of inhibitory effect of curcumin nanoparticles and free curcumin in human telomerase reverse transcriptase gene expression in breast cancer.
Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.
Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene- and targeted radiotherapy approach to bladder carcinoma.
Comparison of screening methods in the detection of bladder cancer.
Comparison of telomerase activity in bladder carcinoma and exfoliated cells collected in urine and bladder washings, using a quantitative assay.
Comparison of telomerase and CD44 expression as diagnostic tumor markers in lesions of the thyroid.
Comparison of telomerase levels before and after differentiation of two cell lines of human neuroblastoma.
Comparison of Telomere Length and Telomerase Activation between Breast Fibroadenoma and Infiltrating Ductal Carcinoma in Malaysian Women.
Complementary treatment of siTERT for improving the antitumor effect of TERT-specific I-131 therapy.
Complex rearrangement of chromosomes 1, 7, 21, 22 in Ewing sarcoma.
Complex regulation of telomerase activity: implications for cancer therapy.
Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?
Complex roles for telomeres and telomerase in breast carcinogenesis.
Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase.
Compromised Telomeric Heterochromatin Promotes ALTernative Lengthening of Telomeres.
Computational selection and experimental validation of allosteric ribozymes that sense a specific sequence of human telomerase reverse transcriptase mRNAs as universal anticancer therapy agents.
Concatenated Catalytic Hairpin Assembly/Hyperbranched Hybridization Chain Reaction Based Enzyme-Free Signal Amplification for the Sensitive Photoelectrochemical Detection of Human Telomerase RNA.
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer.
Concordant expression of the telomerase-associated genes in non-small cell lung cancer.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis.
Conditional telomerase induction causes proliferation of hair follicle stem cells.
Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF.
Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity.
Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders.
Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells.
Consequences of telomere shortening during lifespan.
Consistent decrease in telomere length in parathyroid tumors but alteration in telomerase activity limited to malignancies: preliminary report.
Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells.
Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes.
Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice.
Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Construction of AIEgens-Based Bioprobe with Two Fluorescent Signals for Enhanced Monitor of Extracellular and Intracellular Telomerase Activity.
Construction of the POT1 promoter report gene vector, and the effect and underlying mechanism of the POT1 promoter in regulating telomerase and telomere length.
Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage.
Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands.
Contributory role of microRNAs in anti-cancer effects of small molecule inhibitor of telomerase (BIBR1532) on acute promyelocytic leukemia cell line.
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells.
Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres.
Control of telomere length by a trimming mechanism that involves generation of t-circles.
Control of telomere length by the human telomeric protein TRF1.
Convertible DNA ends-based silver nanoprobes for colorimetric detection human telomerase activity.
Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development.
Cooperation of hTERT, SV40 T antigen and oncogenic Ras in tumorigenesis: a cell transplantation model using bovine adrenocortical cells.
Cooperative role of telomerase activity and p16 expression in the prognosis of non-small-cell lung cancer.
Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases.
Correction to: Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility.
Correlating telomerase activity levels with human neuroblastoma outcomes.
Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma.
Correlation between genetic alterations and growth of human malignant glioma xenografted in nude mice.
Correlation between morphology and telomerase activity in cells from exfoliative lung cytologic specimens.
Correlation between telomerase activity and DNA ploidy in gastric cancer.
Correlation between telomerase activity and telomeric-repeat binding factors in gastric cancer.
Correlation between telomerase and mTOR pathway in cancer stem cells.
Correlation between telomerase expression and terminal restriction fragment length ratio in non-small cell lung cancer--an adjusted measurement and its clinical significance.
Correlation between the expression of hTERT gene and the clinicopathological characteristics of hepatocellular carcinoma.
Correlation between the expression of telomerase reverse transcriptase and proliferative activity in breast cancer cells using an immunocytochemical restaining method.
Correlation of Bmi-1 expression and telomerase activity in human ovarian cancer.
Correlation of clinical features and telomerase activity in human gliomas.
Correlation of dyskerin expression with active proliferation independent of telomerase.
Correlation of hTERT Expression with Cervical Cytological Abnormalities and Human Papillomavirus Infection.
Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression.
Correlation of telomerase activity and telomere length to chemosensitivity.
Correlation of telomerase activity to apoptosis and survival in adult acute lymphoblastic leukemia: an Egyptian single-center study.
Correlation of telomerase activity with development and progression of adult T-cell leukemia.
Correlation of telomerase activity, clinical prognosis and therapy in oral carcinogenesis.
Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors.
Correlations between the expression of hTERT and ? and ? splice variants in human brain tumors.
Correlations of BMI-1 expression and telomerase activity in ovarian cancer tissues.
Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma.
Correspondence re: S. M. Melana et al., Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine. Clin. Cancer Res., 4: 693-696, 1998.
Correspondence re: Seki et al., Diagnosis of pancreatic adenocarcinoma by detection of human telomerase reverse transcriptase messenger RNA in pancreatic juice with sample qualification. Clin. Cancer Res., 7: 1976-1981, 2001.
Cost-Effective Trap qPCR Approach to Evaluate Telomerase Activity: an Important Tool for Aging, Cancer, and Chronic Disease Research.
Cotransfected sodium iodide symporter and human tyroperoxidase genes following human telomerase reverse transcriptase promoter for targeted radioiodine therapy of malignant glioma cells.
Coupling a DNA-Based Machine with Glucometer Readouts for Amplified Detection of Telomerase Activity in Cancer Cells.
CPSF4 activates telomerase reverse transcriptase and predicts poor prognosis in human lung adenocarcinomas.
Creation of a novel telomere-cutting endonuclease based on the EN domain of telomere-specific non-long terminal repeat retrotransposon, TRAS1.
Creation of human tumour cells with defined genetic elements.
CRH inhibits cell growth of human endometrial adenocarcinoma cells via CRH-receptor 1-mediated activation of cAMP-PKA pathway.
CRISPR-dCas9-Guided and Telomerase-Responsive Nanosystem for Precise Anti-Cancer Drug Delivery.
Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus.
Cross-Platform Cancer Cell Identification Using Telomerase-Specific Spherical Nucleic Acids.
Cross-species difference in telomeric function of tankyrase 1.
Crossroads of telomere biology and anticancer drug discovery.
Cryo-EM structure of substrate-bound human telomerase holoenzyme.
Cryptic EWSR1-FLI1 fusions in Ewing sarcoma: potential pitfalls in the diagnostic use of fluorescence in situ hybridization probes.
Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: Identification of a novel enhancer region involved in the regulation of TERT gene.
Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis.
Culture models of human mammary epithelial cell transformation.
Curcumin as Prospective Anti-Aging Natural Compound: Focus on Brain.
Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells.
Curcumin inhibits telomerase activity in human cancer cell lines.
Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells.
Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity.
Current ideas in desmoid tumours.
Current Insights to Regulation and Role of Telomerase in Human Diseases.
Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites.
Current status of GV1001 and other telomerase vaccination strategies in the treatment of cancer.
Cyst fluid telomerase activity predicts the histologic grade of cystic neoplasms of the pancreas.
Cytogenetic and molecular genetic evolution of chronic myeloid leukemia.
Cytogenetic features of human trophoblast cell lines SWAN-71 and 3A-subE.
Cytogenetic, telomere, and telomerase studies in five surgically managed lumbosacral chordomas.
Cytokeratin-20 reverse-transcriptase polymerase chain reaction as a new tool for the detection of circulating tumor cells in peripheral blood and bone marrow of bladder cancer patients.
Cytokine expression in human primary and metastatic melanoma cells: analysis in fresh bioptic specimens.
Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid.
Cytological detection of telomerase activity using an in situ telomeric repeat amplification protocol assay.
Cytostatic concentrations of anticancer agents do not affect telomerase activity of leukaemic cells in vitro.
Cytotoxic effects of caffeic acid undecyl ester are involved in the inhibition of telomerase activity in NALM-6 human B-cell leukemia cells.
Cytotoxic T cell immunity against telomerase reverse transcriptase in humans.
Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinoma.
Cytotoxic T-cell immunity against telomerase reverse transcriptase in colorectal cancer patients.
DD3(PCA3), a very sensitive and specific marker to detect prostate tumors.
ddTRAP: A Method for Sensitive and Precise Quantification of Telomerase Activity.
Deactivation of Telomerase Enzyme and Telomere Destabilization by Natural Products: a Potential Target for Cancer Green Therapy.
Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.
Decellularized matrix from tumorigenic human mesenchymal stem cells promotes neovascularization with galectin-1 dependent endothelial interaction.
Deciphering telomerase structure raises hope for new cancer treatments.
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro.
Decrease in nucleophosmin/B23 mRNA and telomerase activity during indomethacin-induced apoptosis of gastric KATO-III cancer cells.
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.
Decrease of telomere length in thyroid adenomas without telomerase activity.
Decrease of telomeres and increase of interstitial telomeric sites in chromosomes of short-term cultured gastric carcinoma cells detected by fluorescence in situ hybridization.
Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma.
Decreased expression of PinX1 protein predicts poor prognosis of colorectal cancer patients receiving 5-FU adjuvant chemotherapy.
Decreased expression of telomerase-associated RNAs in the proliferation of stem cells in comparison with continuous expression in malignant tumors.
Decreased production of transforming virus and altered antigenic behaviour in cultured avian sarcoma cells.
Decreased telomerase activity is not a reliable indicator of chemosensitivity in testicular cancer cell lines.
Decreasing telomerase activity of adenocarcinoma cancer cell line (AGS) is associated with different concentrations of sodium selenite and cadmium chloride and selenium l methionine.
Dedifferentiation of human hepatocellular carcinoma up-regulates telomerase and Ki-67 expression.
Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations.
Defects in mismatch repair promote telomerase-independent proliferation.
Deficiency of colonic telomerase in ulcerative colitis.
Defining the cooperative genetic changes that temporally drive alveolar rhabdomyosarcoma.
Delivering antisense telomerase RNA by a hybrid adenovirus/ adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells.
Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth.
Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres.
Demonstration of constant upregulation of the telomerase RNA component in human gastric carcinomas using in situ hybridization.
Demonstration of human telomerase reverse transcriptase (hTERT) in human parathyroid tumours by in situ hybridization with a new oligonucleotide probe.
Demonstration of human telomerase reverse transcriptase by in situ hybridization in lung carcinoma.
Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization.
Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors.
Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells.
Depletion of telomerase RNA inhibits growth of gastrointestinal tumors transplanted in mice.
Deregulation of estrogen induced telomerase activity in tamoxifen-resistant breast cancer cells.
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence.
Design and development of PCR-free highly sensitive electrochemical assay for detection of telomerase activity using Nano-based (liposomal) signal amplification platform.
Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells.
Design of a ribozyme targeting human telomerase reverse transcriptase and cloning of it's gene.
Design of telomerase inhibitors for the treatment of cancer.
Design, synthesis and evaluation of human telomerase inhibitors based upon a tetracyclic structural motif.
Detecting cell-free circulating hTERT mRNA in the plasma may identify a subset of nonsmall cell lung cancer patients.
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Detection and characterization of RNA tumor virus-specific DNA in cells.
Detection of Aberrant TERT Promoter Methylation by Combined Bisulfite Restriction Enzyme Analysis for Cancer Diagnosis.
Detection of activity of telomerase in tumor cells using fiber optical biosensors.
Detection of bladder tumours: role of cytology, morphology-based assays, biochemical and molecular markers.
Detection of Brain Tumor Cells in the Peripheral Blood by a Telomerase Promoter-Based Assay.
Detection of breast cancer cells in the bone marrow or peripheral blood: methods and prognostic significance.
Detection of cancer cells in mesenteric vein and peripheral vessels by measuring telomerase activity in patients with colorectal cancer.
Detection of cell cycle- and differentiation stage-dependent human telomerase reverse transcriptase expression in single living cancer cells.
Detection of circulating carcinoma cells by telomerase activity.
Detection of circulating tumor cells in patients with Ewing's sarcoma and peripheral primitive neuroectodermal tumor.
Detection of circulating tumor cells in patients with localized and metastatic prostatic carcinoma: clinical implications.
Detection of colorectal cancer cells in peripheral blood by reverse-transcriptase polymerase chain reaction for cytokeratin 20.
Detection of cytochrome P450-2A6, -3A5 and -4B1 with real-time polymerase chain reaction in prostate tissue.
Detection of HPV E7 Oncoviral Protein in Cervical Lesions by a New Antibody.
Detection of hTERT mRNA in gastrointestinal tract cancer specimens.
Detection of hTERT protein by flow cytometry.
Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer.
Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer.
Detection of human telomerase reverse transcriptase mRNA in cells obtained by lavage of the pleura is not associated with worse outcome in patients with stage I/II non-small cell lung cancer: Results from Cancer and Leukemia Group B 159902.
Detection of human telomerase reverse transcriptase mRNA in urine of patients with bladder cancer: evaluation of an emerging tumor marker.
Detection of human telomerase RNA gene in cervical cancer and precancerous lesions: comparison with cytological and human papillomavirus DNA test findings.
Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformation.
Detection of malignant effusions: comparison of a telomerase assay and cytologic examination.
Detection of Meningeosis neoplastica by real-time quantitation of telomerase activity.
Detection of micrometastasis through tissue-specific gene expression: its promise and problems.
Detection of mRNA of Telomerase Protein in Benign Naevi and Melanomas Using RNAscope.
Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination.
Detection of telomerase activity by the TRAP assay and its variants and alternatives.
Detection of telomerase activity in biopsy samples of colorectal cancer.
Detection of telomerase activity in biopsy specimens for diagnosis of biliary tract cancers.
Detection of telomerase activity in breast masses by fine-needle aspiration.
Detection of telomerase activity in bronchial lavage as an adjunct to cytological diagnosis in lung cancer.
Detection of telomerase activity in cultured cells and tumor tissue of lung carcinoma by modified telomeric repeat amplification protocol.
Detection of telomerase activity in esophageal squamous cell carcinoma and normal esophageal epithelium.
Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications.
Detection of telomerase activity in exfoliated cancer cells obtained from bile.
Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer.
Detection of telomerase activity in human carcinomas using a trap-ELISA method: correlation with hTR and hTERT expression.
Detection of telomerase activity in malignant and nonmalignant skin conditions.
Detection of telomerase activity in oral lesions.
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Detection of telomerase activity in patients with mycosis fungoides.
Detection of telomerase activity in patients with pancreatic cancer.
Detection of telomerase activity in peritoneal lavage fluid from patients with gastric cancer using immunomagnetic beads.
Detection of telomerase activity in prostate needle-biopsy samples.
Detection of telomerase activity in psoriasis lesional skin and correlation with Ki-67 expression and suppression by retinoic acid.
Detection of telomerase activity using microchip electrophoresis.
Detection of telomerase by in situ hybridization and by the polymerase chain reaction-based telomerase activity assay.
Detection of telomerase expression in fine-needle aspirations and fluids.
Detection of telomerase in hepatocellular carcinomas using a PCR ELISA assay: comparison with hTR expression.
Detection of telomerase reverse transcriptase mRNA in biopsy specimens and bile for diagnosis of biliary tract cancers.
Detection of telomerase RNA in the plasma of patients with breast cancer, malignant melanoma or thyroid cancer.
Detection of telomerase status by semiquantitative and in situ assays, and by real-time reverse transcription-polymerase chain reaction (telomerase reverse transcriptase) assay in bladder carcinomas.
Detection of telomerase, its components, and human papillomavirus in cervical scrapings as a tool for triage in women with cervical dysplasia.
Detection of telomerase-positive circulating epithelial cells in ovarian cancer patients.
Detection of TERC amplification in cervical epithelial cells for the diagnosis of high-grade cervical lesions and invasive cancer: a multicenter study in China.
Detection of the presence of catalytic subunit mRNA associated with telomerase gene in exfoliated urothelial cells from patients with bladder cancer.
Determination of qualitative telomerase activity as an adjunct to the diagnosis of pancreatic adenocarcinoma by EUS-guided fine-needle aspiration.
Determination of telomerase activity and telomere length.
Determination of telomerase activity for differential analysis of multifocal renal cell carcinomas.
Determination of telomerase activity in multifocal renal cell carcinoma.
Determination of telomerase activity in squamous cell carcinoma of the penis.
Determination of telomerase activity in stem cells and non-stem cells of breast cancer.
Determination of telomere length and telomerase activity in cattle infected with bovine leukaemia virus (BLV).
Determination of the activity of telomerase in cancer cells by using BSA-protected gold nanoclusters as a fluorescent probe.
Determining the telomerase activity of exfoliated cells in intestinal lavage solution to detect colorectal carcinoma.
Development and immunopathological characteristics of an Alternaria-induced chronic rhinosinusitis mouse model.
Development of a highly sensitive RT-PCR luminometric hybridization assay for human telomerase reverse-transcriptase beta-plus transcript.
Development of a novel assay to quantify serum human telomerase reverse transcriptase messenger RNA and its significance as a tumor marker for hepatocellular carcinoma.
Development of a novel in vitro chemosensitivity assay: telomerase as a possible marker of tumor cell survival.
Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.
Development of a novel telomerase assay using the PPDK-luciferin-luciferase detection system.
Development of Automated Microscopy-Assisted High-Content Multiparametric Assays for Cell Cycle Staging and Foci Quantitation.
Development of highly predictive 3D-QSAR CoMSIA models for anthraquinone and acridone derivatives as telomerase inhibitors targeting G-quadruplex DNA telomere.
Development of novel telomerase inhibitors based on a bisindole unit.
Development of potential anticancer agents that target the telomere sequence.
Development of quantum-dot-encapsulated liposome-based optical nanobiosensor for detection of telomerase activity without target amplification.
Development of retinoblastoma in the absence of telomerase activity.
Development of Sensitive Droplet Digital PCR Assays for Detecting Urinary TERT Promoter Mutations as Non-Invasive Biomarkers for Detection of Urothelial Cancer.
Developmental regulation of telomerase activity in human fetal tissues during gestation.
Dexamethasone effect on the growth rate, the plasminogen activator, and the MMTV RNA dependent DNA polymerase in a mouse mammary tumor cell line.
Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?
Diagnosis of bladder cancer using telomerase activity in voided urine.
Diagnosis of esophagogastric tumors.
Diagnosis of pancreatic cancer by detecting telomerase activity in pancreatic juice: comparison with K-ras mutations.
Diagnosis of parathyroid carcinoma using immunohistochemical staining against hTERT.
Diagnostic accuracy of human telomerase reverse transcriptase mRNA in malignant pleural effusions: A preliminary report for in situ hybridization detection.
Diagnostic and prognostic relevance of expression of human telomerase subunits in oral cancer.
Diagnostic and prognostic TERT promoter mutations in thyroid fine-needle aspiration biopsy.
Diagnostic and prognostic value of the detection of hTERT mRNA in renal tumors.
Diagnostic and therapeutic application of telomerase-specific oncolytic adenoviral agents.
Diagnostic implications of telomerase activity in pleural effusions.
Diagnostic management of benign and malignant pheochromocytoma.
Diagnostic performance of HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR assays on formalin-fixed paraffin-embedded cervical tissue specimens from women with cervical cancer.
Diagnostic roles of proliferative markers in pathological Grade of T1 Urothelial Bladder Cancer.
Diagnostic usefulness of telomerase activity in nasopharyngeal carcinoma.
Diagnostic Value of Methylated Human Telomerase Reverse Transcriptase in Human Cancers: A Meta-Analysis.
Diagnostic value of telomerase expression in breast fine-needle aspiration biopsies.
Diagnostic value of urinary molecular markers in bladder cancer.
Diagnostics, prognostic and therapeutic exploitation of telomeres and telomerase in leukemias.
Diepitope multiple antigen peptide of hTERT trigger stronger anti-tumor immune responses in vitro.
Differences in telomerase activity and the effects of AZT in aneuploid and euploid cells in colon cancer.
Differences in telomerase activity between colon and rectal cancer.
Differences in the expression of telomerase and prostate-specific membrane antigen in non-advanced prostatic cancer.
Different amplification patterns of the human telomerase RNA gene in invasive cervical carcinomas and cervical intraepithelial neoplasia grade III.
Different assessments of immunohistochemically stained Ki-67 and hTERT in glioblastoma multiforme yield variable results: a study with reference to survival prognosis.
Different mRNA expression profile during tumor progression in a well-differentiated liposarcoma--A microdissection approach.
Different roles of p53 in the regulation of DNA damage caused by 1,2-heteroannelated anthraquinones and doxorubicin.
Different telomere maintenance mechanisms in alveolar and embryonal rhabdomyosarcoma.
Differential Control of Growth, Apoptotic Activity, and Gene Expression in Human Breast Cancer Cells by Extracts Derived from Medicinal Herbs Zingiber officinale.
Differential cytotoxic effects of sodium meta-arsenite on human cancer cells, dental papilla stem cells and somatic cells correlate with telomeric properties and gene expression.
Differential expression of full-length telomerase reverse transcriptase mRNA and telomerase activity between normal and malignant renal tissues.
Differential expression of human telomerase catalytic subunit mRNA by in situ hybridization in pheochromocytomas.
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow.
Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions.
Differential expression of telomerase activity in neuroendocrine lung tumours: correlation with gene product immunophenotyping.
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours.
Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity.
Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene.
Differential induction in telomerase activity among bladder cancer patients and controls on gamma-radiation.
Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma, and glioma cells in culture.
Differential Lysis of Tumors by Polyclonal T Cell Lines and T Cell Clones Specific for hTERT.
Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells.
Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis.
Differential regulation of telomerase activity and TERT expression during brain development in mice.
Differential Regulation of Telomerase Reverse Transcriptase Promoter Activation and Protein Degradation by Histone Deacetylase Inhibition.
Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms.
Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors.
Differential telomerase expression and telomere length in primary intracranial tumors.
Differential telomerase expression in human primary intracranial tumors.
Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.
Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis.
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis.
Differentially expressed genes throughout the cellular immortalization processes are quite different between normal human fibroblasts and endothelial cells.
Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms.
Differentiation linked regulation of telomerase activity by Makorin-1.
Dihydropyrazole derivatives as telomerase inhibitors: Structure-based design, synthesis, SAR and anticancer evaluation in vitro and in vivo.
Dimeric aryl-substituted imidazoles may inhibit ALT cancer by targeting the multimeric G-quadruplex in telomere.
Dimethyl sulfoxide (DMSO) causes a reversible inhibition of telomerase activity in a Burkitt lymphoma cell line.
Diosgenin inhibits hTERT gene expression in the A549 lung cancer cell line.
Direct HPV E6/Myc interactions induce histone modifications, Pol II phosphorylation, and hTERT promoter activation.
Discovery of (4-bromophenyl)(3-hydroxy-4-methoxyphenyl)methanone through upregulating hTERT induces cell apoptosis and ERS.
Discriminating association of a common telomerase reverse transcriptase promoter polymorphism with telomere parameters in non-small cell lung cancer with or without epidermal growth factor receptor mutation.
Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.
Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells.
Dissemination of cancer cells into circulation occurs by incisional biopsy of oral squamous cell carcinoma.
Dissociation of telomere dynamics from telomerase activity in human thyroid cancer cells.
Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential.
Distinct mitotic segregation errors mediate chromosomal instability in aggressive urothelial cancers.
Distinct profiles of TERT promoter mutations and telomerase expression in head and neck cancer and cervical carcinoma.
Distinct TERT promoter C228T and C250T mutations in a patient with an oligodendroglioma: A case report.
Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan.
Distinguishing tumor cells via analyzing intracellular telomerase activity.
Distribution and prognostic significance of human telomerase reverse transcriptase (hTERT) expression in giant-cell tumor of bone.
Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system.
Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas.
Diverse regulatory manners of human telomerase reverse transcriptase.
DKC1 gene mutation in a Taiwanese kindred with X-linked dyskeratosis congenita.
DNA damaging bystander signalling from stem cells, cancer cells and fibroblasts after Cr(VI) exposure and its dependence on telomerase.
DNA G-quadruplexes, telomere-specific proteins and telomere-associated enzymes as potential targets for new anticancer drugs.
DNA helicases as targets for anti-cancer drugs.
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
DNA methylation of the TERT promoter and its impact on human cancer.
DNA Methylation Profiling of hTERT Gene Alongside with the Telomere Performance in Gastric Adenocarcinoma.
DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value.
DNA Related Enzymes as Molecular Targets for Antiviral and Antitumoral Chemotherapy. A Natural Overview of the Current Perspectives.
DNA repair proteins and telomerase reverse transcriptase in the cochlear lateral wall of cisplatin-treated rats.
DNA tetrahedral scaffolds-based platform for the construction of electrochemiluminescence biosensor.
DNA-Damaging Anticancer Drugs - a Perspective for DNA Repair-Oriented Therapy.
DNA-fueled molecular machine for label-free and non-enzymatic ultrasensitive detection of telomerase activity.
DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres.
DNAzyme-Based Probes for Telomerase Detection in Early-Stage Cancer Diagnosis.
Does structural commonality of metal complex formation by PAC-1 (anticancer), DHBNH (anti-HIV), AHL (autoinducer), and UCS1025A (anticancer) denote mechanistic similarity? Signal transduction and medical aspects.
Does telomerase reverse transcriptase induce functional de-differentiation of human endothelial cells?
Does the presence of circulating tumor cells in the venous drainage of curative colorectal cancer resections determine prognosis? A meta-analysis.
Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells.
Down-regulation of human telomerase reverse transcriptase through specific activation of RNAi pathway quickly results in cancer cell growth impairment.
Down-regulation of p21 contributes to apoptosis induced by HPV E6 in human mammary epithelial cells.
Down-regulation of telomerase activity by anticancer drugs in human ovarian cancer cells.
Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol.
Down-regulation of telomerase activity in malignant glioma cells by p27KIP1.
Down-regulation of TRF1, TRF2 and TIN2 genes is important to maintain telomeric DNA for gastric cancers.
Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes.
Downregulation of high mobility group box 1 modulates telomere homeostasis and increases the radiosensitivity of human breast cancer cells.
Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.
Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells.
Downregulation of telomerase activity by diclofenac and curcumin is associated with cell cycle arrest and induction of apoptosis in colon cancer.
Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells.
Doxorubicin modulates telomerase activity in Ewing's sarcoma in vitro and in vivo.
Dramatic increase of telomerase activity during dendritic cell differentiation and maturation.
Drop of connexins: a possible link between aging and cancer?
Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies.
Dual induction of PKR with E2F-1 and IFN-alpha to enhance gene therapy against hepatocellular carcinoma.
Dual mode of binding of anti cancer drug epirubicin to G-quadruplex [d-(TTAGGGT)]4 containing human telomeric DNA sequence induces thermal stabilization.
Dual promoter-controlled oncolytic adenovirus CG5757 has strong tumor selectivity and significant antitumor efficacy in preclinical models.
Dual regulation of telomerase activity through c-Myc-dependent inhibition and alternative splicing of hTERT.
Dual roles of c-Myc in the regulation of hTERT gene.
Dual-Mode Au Nanoprobe Based on Surface Enhancement Raman Scattering and Colorimetry for Sensitive Determination of Telomerase Activity Both in Cell Extracts and in the Urine of Patients.
Dynamic telomerase gene suppression via network effects of GSK3 inhibition.
Dynamics of human telomerase RNA structure revealed by antisense oligonucleotide technique.
Dynamics of telomere erosion in transformed and non-transformed avian cells in vitro.
Dynamics of telomere's length and telomerase activity in Philadelphia chromosome negative myeloproliferative neoplasms.
Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation.
Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.
Dyskeratosis congenita: a disorder of defective telomere maintenance?
Dyskeratosis congenita: advances in the understanding of the telomerase defect and the role of stem cell transplantation.
Dyskeratosis congenita: molecular insights into telomerase function, ageing and cancer.
Dyskerin and cancer: more than telomerase. The defect in mRNA translation helps in explaining how a proliferative defect leads to cancer.
Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.
Dysregulation of telomerase activity and expression in lymphokine-activated killer cells from advanced cancer patients: possible involvement in cancer-associated immunosuppression mechanism.
E2F-1 represses transcription of the human telomerase reverse transcriptase gene.
E2F1 acts as a negative feedback regulator of c-Myc?induced hTERT transcription during tumorigenesis.
E2F1 and telomerase: alliance in the dark side.
E6-associated protein is required for human papillomavirus type 16 E6 to cause cervical cancer in mice.
Early diagnosis for colorectal cancer in China.
Early growth response-1 mediates up-regulation of telomerase in placenta.
Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cells.
Ectopic expression of c-myc fails to overcome downregulation of telomerase activity induced by herbimycin A, but ectopic hTERT expression overcomes it.
Editorial retraction. Down-regulation of human telomerase reverse transcriptase through anti-c-myc siRNA in human colon cancer Colo 320 cells.
Effect of 2'-deoxyisoguanosine on the growth of human tumor and normal cell lines.
Effect of acetic acid on telomerase activity in cervical intraepithelial neoplasia.
Effect of actinomycin D on nucleic acid hybridization: the cause of erroneous DNA elongation during DNA synthesis of RNA tumor viruses in vitro.
Effect of all-trans retinoic acid on telomerase activity in ovarian cancer cells.
Effect of antisense human telomerase RNA on malignant phenotypes of gastric carcinoma.
Effect of blocking VEGF, hTERT and Bcl-xl by multiple shRNA expression vectors on the human laryngeal squamous carcinoma xenograft in nude mice.
Effect of ethidium bromide on transplanted virus-induced tumor cells.
Effect of NS398 on metastasis-associated gene expression in a human colon cancer cell line.
Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells.
Effect of penclomedine (NSC-338720) on telomere fusions, chromatin blebbing, and cell viability with and without telomerase activity and abrogated p53 function.
Effect of proinflammatory cytokines on the expression and regulation of human beta-defensin 2 in human dental pulp cells.
Effect of silencing key proteins in telomerase mechanism and alternative lengthening of telomeres mechanism in laryngeal cancer cells.
Effect of single-nucleotide polymorphism in TERT promoter on follicular thyroid tumor development.
Effect of telomerase inhibition on preclinical models of malignant rhabdoid tumor.
Effect of telomere and telomerase interactive agents on human tumor and normal cell lines.
Effect of therapies-mediated modulation of telomere and/or telomerase on cancer cells radiosensitivity.
Effective gene-viral therapy for telomerase-positive cancers by selective replicative-competent adenovirus combining with endostatin gene.
Effective Inhibition of Cancer Cell Growth by a Novel Tripartite Transfection Complex Containing Ribbon Antisense Molecules to hTR.
Effectiveness of indomethacin as an antitumor agent in Colon 26-bearing conventional and nude mice, and telomerase activity in the tumors.
Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer.
Effects of aspirin on metastasis-associated gene expression detected by cDNA microarray.
Effects of AZT and RNA-protein complex (FA-2-b-beta) extracted from Liang Jin mushroom on apoptosis of gastric cancer cells.
Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.
Effects of chemopreventive and antitelomerase agents on the spontaneous immortalization of breast epithelial cells.
Effects of combined siRNA-TR and -TERT on telomerase activity and growth of bladder transitional cell cancer BIU-87 cells.
Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes.
Effects of dipotassium-trioxohydroxytetrafluorotriborate, K2[B3O3F4OH], on cell viability and gene expression of common human cancer drug targets in a melanoma cell line.
Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines.
Effects of genomic imbalances on telomerase activity in gastric cancer: clues to telomerase regulation.
Effects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells.
Effects of nano-encapsulated curcumin-chrysin on telomerase, MMPs and TIMPs gene expression in mouse B16F10 melanoma tumour model.
Effects of PCB126 and PCB153 on telomerase activity and telomere length in undifferentiated and differentiated HL-60 cells.
Effects of phosphorothioate anti-sense oligodeoxynucleotides on colorectal cancer cell growth and telomerase activity.
Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells.
Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway.
Effects of Reverse Transcriptase Inhibitors on Proliferation, Apoptosis, and Migration in Breast Carcinoma Cells.
Effects of tea polyphenols on telomerase activity of a tongue cancer cell line: a preliminary study.
Effects of telomerase activity on carcinogenesis and survival in laryngeal carcinoma.
Effects of telomerase and telomere length on epidermal stem cell behavior.
Effects of telomerase inhibitor on epigenetic chromatin modification enzymes in malignancies.
Effects of the central potassium ions on the G-quadruplex and stabilizer binding.
Effects of three diterpenoids on tumour cell proliferation and telomerase activity.
Effects of treatment with platinum azidothymidine and azidothymidine on telomerase activity and bcl-2 concentration in hepatocellular carcinoma- induced rats.
Efficiency of diagnostic biomarkers among colonic schistosomiasis Egyptian patients.
Efficient expression of recombinant human telomerase inhibitor 1 (hPinX1) in Pichia pastoris.
Efficient inhibition of human telomerase activity by antisense oligonucleotides sensitizes cancer cells to radiotherapy.
Efficient Inhibition of Human Telomerase Reverse Transcriptase Expression by RNA Interference Sensitizes Cancer Cells to Ionizing Radiation and Chemotherapy.
Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy.
EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis.
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.
EGFR Tyrosine Kinase Inhibitor Pelitinib Regulates Radiation-Induced p65-Dependent Telomerase Activation in Squamous Cell Carcinoma.
eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase.
Electrochemical determination of the activity and inhibition of telomerase based on the interaction of DNA with molybdate.
Electrochemical telomerase assay for screening for oral cancer.
Electron-transfer quenching of nucleic acid-functionalized CdSe/ZnS quantum dots by doxorubicin: A versatile system for the optical detection of DNA, aptamer-substrate complexes and telomerase activity.
Electronic energy changes associated with Guanine quadruplex formation: an investigation at the atomic level.
Elevated levels of telomerase activity in malignant pheochromocytoma.
Elevated telomerase activity in essential thrombocythemia with extreme thrombocytosis.
Elevated telomerase activity, c-MYC-, and hTERT mRNA expression: association with tumour progression in malignant lipomatous tumours.
Elevation of telomerase activity positively correlates to poor prognosis of patients with non-small cell lung cancer.
Embryo arrest and reactivation: potential candidates controlling embryonic diapause in the tammar wallaby and mink1.
Emerging biomarkers in glioblastoma.
Emerging immunotherapeutic strategies targeting telomerases in genitourinary tumors.
Emerging role of p53, bcl-2 and telomerase activity in Egyptian breast cancer patients.
Enantioselective Effects of o,p'-DDT on Cell Invasion and Adhesion of Breast Cancer Cells: Chirality in Cancer Development.
Endogenous RNA-directed DNA polymerase activity in virions of RNA tumor viruses and in a fraction from normal chicken cells.
Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.
Endoplasmic reticulum stress activates telomerase.
Energetics of Ligand Binding to G-Quadruplexes.
Energetics of quadruplex-drug recognition in anticancer therapy.
Energetics of the human Tel-22 quadruplex-telomestatin interaction: a molecular dynamics study.
Enforced expression of a truncated form of Bax-alpha (tBax) driven by human telomerase reverse transcriptase (hTERT) promoter sensitizes tumor cells to chemotherapeutic agents or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation.
Enhanced activity of cloned hamster TERT gene promoter in transformed cells.
Enhanced antitumor effect against human telomerase reverse transcriptase (hTERT) by vaccination with chemotactic-hTERT gene-modified tumor cell and the combination with anti-4-1BB monoclonal antibodies.
Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: preclinical evaluation of chemovirotherapy.
Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia.
Enhanced expression of telomerase activity in thymoma and thymic carcinoma tissues: a clinicopathologic study.
Enhanced growth suppression of TERT-positive tumor cells by oncolytic adenovirus armed with CCL20 and CD40L.
Enhanced suicide gene therapy by chimeric tumor-specific promoter based on HSF1 transcriptional regulation.
Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells.
Enhancement of nanoparticle-mediated double suicide gene expression driven by 'E9-hTERT promoter' switch in dedifferentiated thyroid cancer cells.
Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA.
Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity.
Enterolactone Reduces Telomerase Activity and The Level of Its Catalytic Subunit in Breast Cancer Cells.
Enzymatic activity of endogenous telomerase associated with intact nuclei from human leukemia CEM cells.
Epidemiologic evidence for a role of telomere dysfunction in cancer etiology.
Epidemiology and molecular pathology at crossroads to establish causation: molecular mechanisms of malignant transformation.
Epidermal growth factor receptor and epidermal growth factor receptor variant III gene expression in metastatic colorectal cancer.
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.
Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway.
Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention.
Epigenetic features in regulation of telomeres and telomerase in stem cells.
Epigenetic mechanisms regulate placental c-myc and hTERT in normal and pathological pregnancies; c-myc as a novel fetal DNA epigenetic marker for pre-eclampsia.
Epigenetic perturbation driving asleep telomerase reverse transcriptase: Possible therapeutic avenues in carcinoma.
Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells.
Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation.
Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells.
Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review).
Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.
Epigenetic targets of bioactive dietary components for cancer prevention and therapy.
Epoxy-functionalized macroporous carbon with embedded platinum nanoparticles for electrochemical detection of telomerase activity via telomerase-triggered catalytic hairpin assembly.
Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells.
Epstein-Barr virus-encoded RNAs (EBERs) complement the loss of Herpesvirus telomerase RNA (vTR) in virus-induced tumor formation.
Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma.
Equine telomeres and telomerase in cellular immortalisation and ageing.
Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals.
Erucin and Benzyl Isothiocyanate Suppress Growth of Late Stage Primary Human Ovarian Carcinoma Cells and Telomerase Activity In Vitro.
Essential role for nuclear factor kappaB in ischemic preconditioning for ischemia-reperfusion injury of the mouse liver.
Essential roles of telomerase reverse transcriptase hTERT in cancer stemness and metastasis.
Establishing Cell-Based Reporter Systems for the Analysis of hTERT Expression.
Establishing tumor cell lines from aggressive telomerase-positive chordomas of the skull base. Technical note.
Establishment and characterization of a human cell line from paediatric cerebellar glioblastoma multiforme.
Establishment and characterization of a new cell line derived from a human primary breast carcinoma.
Establishment and characterization of HKESC-1, a new cancer cell line from human esophageal squamous cell carcinoma.
Establishment and characterization of MACL-1 and MGSO-3 cell lines derived from human primary breast cancer.
Establishment and characterization of OCUT-1, an undifferentiated thyroid cancer cell line expressing high level of telomerase.
Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15.
Establishment of an immortal chicken embryo liver-derived cell line.
Establishment of an immortalized human hepatic stellate cell line to develop antifibrotic therapies.
Establishment of duck cell line derived from experimental tumor induced by 20-methylcholanthrene.
Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development.
Establishment of novel human esophageal cancer cell line in relation to telomere dynamics and telomerase activity.
Estrogen activates telomerase.
Estrogen and progesterone receptors and telomerase enzyme immunohistochemical detection in gestational trophoblastic tumors.
Estrogen Receptor-alpha Mediates the Effects of Estradiol on Telomerase Activity in Human Mesenchymal Stem Cells.
Estrogen, Telomerase, Ovarian Aging And Cancer.
Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes.
Etoposide (VP-16) elicits apoptosis following prolonged G2-M cell arrest in p53-mutated human non-small cell lung cancer cells.
Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.
Ets2 Transcription Factor, Telomerase Activity And Breast Cancer.
Evaluation of an assay for detecting telomerase activity in neoplastic tissues of dogs.
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Evaluation of combined h-TERT, bcl-2, and caspases 3 and 8 expression in cutaneous malignant melanoma based on tissue microarrays and computerized image analysis.
Evaluation of Energy Balance on Human Telomerase Reverse Transcriptase (hTERT) Alternative Splicing by Semi-quantitative RT-PCR in Human Umbilical Vein Endothelial Cells.
Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancer.
Evaluation of intracellular telomerase activity through cascade DNA logic gates.
Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review.
Evaluation of serum human telomerase reverse transcriptase as a novel marker for cervical cancer.
Evaluation of synovial cytokine patterns in rheumatoid arthritis and osteoarthritis by quantitative reverse transcription polymerase chain reaction.
Evaluation of tankyrase inhibition in whole cells.
Evaluation of telomerase activation in head and neck cancer.
Evaluation of telomerase activity in cutaneous melanocytic proliferations.
Evaluation of telomerase activity in gingival fibroblasts of cyclosporine-treated patients.
Evaluation of telomerase activity in patients with chronic B lymphocytic leukemia versus age matched controls. Correlation between telomerase activity and bone marrow infiltration.
Evaluation of telomerase in canine mammary tissues by immunohistochemical analysis and a polymerase chain reaction-based enzyme-linked immunosorbent assay.
Evaluation of telomerase in non-melanoma skin cancer.
Evaluation of telomerase in the development and progression of colon cancer.
Evaluation of telomerase mRNA (hTERT) in colon cancer.
Evaluation of telomerase-targeted therapies in canine cancer cell lines.
Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.
Evaluation of urinary human telomerase reverse transcriptase mRNA and scatter factor protein as urine markers for diagnosis of bladder cancer.
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-associated PML bodies.
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
Evidence for elevated telomerase activity in small cell carcinoma of the bladder.
Evidence for inactivation of distinct telomerase repressor genes in different types of human cancers.
Evidence for ovarian granulosa stem cells: telomerase activity and localization of the telomerase ribonucleic acid component in bovine ovarian follicles.
Evidence for telomerase involvement in the angiogenesis of astrocytic tumors: expression of human telomerase reverse transcriptase messenger RNA by vascular endothelial cells.
Evidence for the isolation, growth, and characterization of malignant cells in primary cultures of human tumors.
Evidence for UV-associated activation of telomerase in human skin.
Evidence of particle-associated RNA-directed DNA polymerase and high molecular weight RNA in human gastrointestinal and lung malignancies.
Evidence of recombinant ecotropic provirus integration in thymic lymphomas induced by direct or indirect radiation effects.
Evolving views of telomerase and cancer.
Ewing family tumors: potential prognostic value of reverse-transcriptase polymerase chain reaction detection of minimal residual disease in peripheral blood samples.
EWS/ETS fusions activate telomerase in Ewing's tumors.
Ex vivo expanded telomerase-specific T cells are effective in an orthotopic mouse model for pancreatic adenocarcinoma.
Exercise, Telomeres, and Cancer: "The Exercise-Telomere Hypothesis".
Exonuclease I manipulating primer-modified gold nanoparticles for colorimetric telomerase activity assay.
Experimental infection of a cat kidney cell line with the mouse mammary tumor virus.
Experimental study on anti-neoplastic activity of epigallocatechin-3-gallate to digestive tract carcinomas.
Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.
Exploring hTERT promoter methylation in cutaneous T-cell lymphomas.
Exploring the epigenetic regulation of telomerase reverse transcriptase (TERT) in human cancer cell lines.
Exploring the mechanism of inhibition of human telomerase by cysteine-reactive compounds.
Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer.
Expression and alternative splicing pattern of human telomerase reverse transcriptase in human lung cancer cells.
Expression and clinical significance of microRNA-1246 in human oral squamous cell carcinoma.
Expression and distribution of human telomerase catalytic component, hTERT, in human breast tissues.
Expression and suppression of human telomerase RNA.
Expression distribution of cancer stem cells, epithelial to mesenchymal transition, and telomerase activity in breast cancer and their association with clinicopathologic characteristics.
Expression of (NES-)hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stress.
Expression of cancer testis antigens in head and neck squamous cell carcinomas.
Expression of checkpoint kinase 2 in breast carcinomas: correlation with key regulators of tumor cell proliferation, angiogenesis, and survival.
Expression of differentiation melanoma-associated antigen genes is associated with favorable disease outcome in advanced-stage melanomas.
Expression of functional alternative telomerase RNA component gene in mouse brain and in motor neurons cells protects from oxidative stress.
Expression of HPV-16 E6 Protein and p53 Inactivation Increases the Uterine Cervical Cancer Invasion.
Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.
Expression of hTERT in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma - an Immunohistochemical Analysis.
Expression of human sequences related to those of mouse mammary tumor virus.
Expression of human telomerase reverse transcriptase and correlation with telomerase activity in placentas with and without intrauterine growth retardation.
Expression of human telomerase reverse transcriptase and cyclin-D1 in olfactory neuroblastoma.
Expression of human telomerase reverse transcriptase in gastrointestinal stromal tumors occurs preferentially in malignant neoplasms.
Expression of human telomerase reverse transcriptase in regenerative and precancerous lesions of cirrhotic livers.
Expression of human telomerase reverse transcriptase in thyroid follicular neoplasms: an immunohistochemical study.
Expression of human telomerase reverse transcriptase in vulvar intraepithelial neoplasia and squamous cell carcinoma: an immunohistochemical study with survivin and p53.
Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions.
Expression of human telomerase reverse transcriptase, the catalytic subunit of telomerase, is associated with the development of persistent disease in complete hydatidiform moles.
Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.
Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer.
Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors.
Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis.
Expression of survivin and human telomerase reverse transcriptase in extramammary Paget's disease.
Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells.
Expression of telomerase & its significance in the diagnosis of pancreatic cancer.
Expression of telomerase (hTERT) in aldosterone-producing adrenocortical tumors.
Expression of telomerase activity and oxidative stress in human hepatocellular carcinoma with cirrhosis.
Expression of telomerase activity and telomerase RNA in human soft tissue sarcomas.
Expression of telomerase activity in human chorion.
Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation.
Expression of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in gastric adenocarcinomas.
Expression of telomerase activity, telomerase RNA component and telomerase catalytic subunit gene in lung cancer.
Expression of telomerase catalytic component, telomerase reverse transcriptase, in human gastric carcinomas.
Expression of telomerase component genes in hepatocellular carcinomas.
Expression of telomerase extends the lifespan and enhances osteogenic differentiation of adipose tissue-derived stromal cells.
Expression of telomerase genes in cancer development in atypical hyperplasia of the mammary duct.
Expression of telomerase genes in thyroid carcinoma.
Expression of telomerase in normal and malignant rat hepatic epithelia.
Expression of telomerase inhibits hydroxyl radical-induced apoptosis in normal telomerase negative human lung fibroblasts.
Expression of telomerase reverse transcriptase in radiation-induced chronic human skin ulcer.
Expression of telomerase reverse transcriptase mRNA and its quantitative analysis in human endometrial cancer.
Expression of telomerase RNA component correlates with the MIB-1 proliferation index in ependymomas.
Expression of telomerase RNA in oesophageal and oral cancer.
Expression of telomerase RNA, telomerase activity, and telomere length in human gliomas.
Expression of telomerase subunits and localization of telomerase activation in hydatidiform mole.
Expression of telomerase subunits in normal and neoplastic prostate epithelial cells isolated by laser capture microdissection.
Expression of telomerase-associated genes: reflection of telomerase activity in gastric cancer?
Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade.
Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas.
Expression of telomeric repeat binding factor 1 protein in nonsmall cell lung cancer with human telomerase reverse transcriptase positive.
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.
Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer.
Expression of the full-length telomerase reverse transcriptase (hTERT) transcript in both malignant and normal gastric tissues.
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1.
Expression of the human telomerase reverse transcriptase in pheochromocytoma and neuroblastoma tissues.
Expression of the human telomerase reverse transcriptase is not related to telomerase activity in normal and malignant renal tissue.
Expression of the immediate early IE180 protein under the control of the hTERT and CEA tumor-specific promoters in recombinant pseudorabies viruses: Effects of IE180 protein on promoter activity and apoptosis induction.
Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells.
Expression of the RNA component of human telemorase (hTR) in ThinPrep preparations from bladder washings.
Expression of the RNA component of human telomerase (hTR) in prostate cancer, prostatic intraepithelial neoplasia, and normal prostate tissue.
Expression of the RNA component of human telomerase in adult testicular germ cell neoplasia.
Expression of the RNA component of telomerase in Wilms tumor and nephrogenic rest recapitulates renal embryogenesis.
Expression of Thy 1 antigen in normal and neoplastic mammary cells of mice.
Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of a hTERT promoter at the 3'-side of the transgene.
Expression of VEGF, HGF, IL-6, IL-8, MMP-9, Telomerase in Peripheral Blood of Patients with Head and Neck Squamous Cell Carcinoma.
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
Expression Pattern of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase (hTERT) in Cancer Cell Lines Was not Associated with the Origin of the Cells.
Expression pattern of telomerase reverse transcriptase in rectal carcinoma predicts tumor radiosensitivity, local recurrence and disease-free survival.
Expression profile of telomerase subunits in human pleural mesothelioma.
Expression profile of the putative catalytic subunit of the telomerase gene.
Expression profile of the telomeric complex discriminates between benign and malignant pheochromocytoma.
Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
Expression profiles of subtracted mRNAs during cellular senescence in human mesenchymal stem cells derived from bone marrow.
Expression profiling of osteosarcoma cells transfected with MDR1 and NEO genes: regulation of cell adhesion, apoptosis, and tumor suppression-related genes.
Expression-patterns of the RNA component (hTR)and the catalytic subunit (hTERT) of human telomerase in nonneoplastic prostate tissue, prostatic intraepithelial neoplasia, and prostate cancer.
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
Extensive in vivo self-renewal, long-term reconstitution capacity, and hematopoietic multipotency of Pax5-deficient precursor B-cell clones.
Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress.
Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications.
Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase delta-mediated telomere-telomere recombination in Saccharomyces cerevisiae.
Extratelomeric functions of telomerase.
Facile assay of telomerase activity utilizing a DNA-detectable chemiluminogenic reagent.
Facile synthesis of fluorescent tungsten oxide quantum dots for telomerase detection based on the inner filter effect.
Facile, Fast-Responsive, and Photostable Imaging of Telomerase Activity in Living Cells with a Fluorescence Turn-On Manner.
FADD gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter to restrict induction of apoptosis to tumors in vitro and in vivo.
False elevation of human chorionic gonadotropin in a patient with testicular cancer.
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops.
FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops.
Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.
Fate of viral RNA of murine leukemia virus after infection.
Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies.
Feedback regulation of telomerase reverse transcriptase: new insight into the evolving field of telomerase in cancer.
Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line.
Ferrocenylnaphthalene Diimide-Based Electrochemical Detection of Aberrant Methylation in hTERT Gene.
Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.
Fibrosis-dependent mechanisms of hepatocarcinogenesis.
FIP-gts potentiate autophagic cell death against cisplatin-resistant urothelial cancer cells.
FISH comets show that the salvage enzyme TK1 contributes to gene-specific DNA repair.
Flow cytometric analysis of DNA, telomerase content and multi-gene expression in esophageal epithelial dysplasia.
Flow cytometric detection of human telomerase reverse transcriptase (hTERT) expression in a subpopulation of bone marrow cells.
Fluorescence detection of DNA, adenosine-5'-triphosphate (ATP), and telomerase activity by zinc(II)-protoporphyrin IX/G-quadruplex labels.
Fluorescence detection of telomerase activity in cancer cell extracts based on autonomous exonuclease III-assisted isothermal cycling signal amplification.
Fluorescence detection of telomerase activity in cancer cells based on isothermal circular strand-displacement polymerization reaction.
Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling.
Fluorescence Imaging of Intracellular Telomerase Activity Using Enzyme-Free Signal Amplification.
Fluorescence in situ hybridization analysis of the hTERC region in acute myeloid leukemia patients.
Fluorescence-based melting assays for studying quadruplex ligands.
Focal intratumoral heterogeneity for telomerase activity in human prostate cancer.
Folding heterogeneity in the essential human telomerase RNA three-way junction.
For better or worse? Telomerase inhibition and cancer.
Forever Young: Structural Stability of Telomeric Guanine Quadruplexes in the Presence of Oxidative DNA Lesions*.
Formation of G-quadruplex-hemin DNAzyme based on human telomere elongation and its application in telomerase activity detection.
Frequency of telomerase-specific CD8+ T lymphocytes in patients with cancer.
Frequency of TERT promoter mutations in human cancers.
Frequency of TERT Promoter Mutations in Prostate Cancer.
Frequent amplification of the telomerase reverse transcriptase gene in human tumors.
Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer.
Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells.
Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.
Frequent TERT Promoter Mutations in Ocular Surface Squamous Neoplasia.
FRET investigation toward DNA tetrahedron-based ratiometric analysis of intracellular telomerase activity.
Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.
From stem cells to cancer: balancing immortality and neoplasia.
Full length RTEL1 is required for the elongation of the single-stranded telomeric overhang by telomerase.
Fumagillin treatment of hepatocellular carcinoma in rats: an in vivo study of antiangiogenesis.
Function of HSP90 and p23 in the telomerase complex of thyroid tumors.
Functional analysis of the pseudoknot structure in human telomerase RNA.
Functional and dysfunctional roles of quadruplex DNA in cells.
Functional and mechanistic analysis of telomerase: An antitumor drug target.
Functional assessment of pharmacological telomerase activators in human T cells.
Functional benefit and molecular mechanism of vitamin C against perfluorooctanesulfonate-associated leukemia.
Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells.
Functional comparison of the human epidermal growth factor receptor and telomerase reverse transcriptase promoters in canine tumor cells.
Functional genetics and experimental models of human cancer.
Functional genomics of tumor suppressor miR-196b in T-cell acute lymphoblastic leukemia.
Functional Loss of ATRX and TERC Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells.
Functional Self-Assembled DNA Nanohydrogels for Specific Telomerase Activity Imaging and Telomerase-Activated Antitumor Gene Therapy.
Functionalization of Graphene Oxide with Porphyrins: Synthetic Routes and Biological Applications.
Functionalized nanoprobes for in situ detection of telomerase.
Fundamental insights into the interaction between telomerase/TERT and intracellular signaling pathways.
Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.
G-Quadruplex DNA as a target for drug design.
G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase.
G-quadruplex preferentially forms at the very 3' end of vertebrate telomeric DNA.
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells.
G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells.
G-quadruplex structure: a target for anticancer therapy and a probe for detection of potassium.
G-quadruplexes as therapeutic targets.
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression.
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Gain of human telomerase RNA gene is associated with progression of cervical intraepithelial neoplasia grade I or II.
Gain of the human telomerase RNA gene TERC at 3q26 is strongly associated with cervical intraepithelial neoplasia and carcinoma.
Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells.
Gastric cancer cell detection in peritoneal lavage: RT-PCR for carcinoembryonic antigen transcripts versus the combined cytology with peritoneal carcinoembryonic antigen levels.
Gastric cancer with high telomerase activity shows rapid development and invasiveness.
Gastrin regulates growth of human pancreatic cancer in a tonic and autocrine fashion.
Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1? and VEGF receptors.
Gastrointestinal stromal tumors - quantitative detection of the Ki-67, TPX2, TOP2A, and hTERT telomerase subunit mRNA levels to determine a proliferation activity and a potential for aggressive biological behavior.
Gastrointestinal stromal tumors of the vermiform appendix: clinicopathologic, immunohistochemical, and molecular study of 2 cases with literature review.
Gastrointestinal tract antigenic profile of cotton-top tamarin, Saguinus oedipus, is similar to that of humans with inflammatory bowel disease.
Gefitinib induces apoptosis and decreases telomerase activity in MDA-MB-231 human breast cancer cells.
Gelatin nanoparticles transport DNA probes for detection and imaging of telomerase and microRNA in living cells.
Gene expression analysis of the catalytic subunit of human telomerase (hEST2) in the differential diagnosis of serous effusions.
Gene expression for suppressors of telomerase activity (telomeric-repeat binding factors) in breast cancer.
Gene expression of 5-fluorouracil metabolic enzymes in primary gastric cancer: correlation with drug sensitivity against 5-fluorouracil.
Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter.
Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma.
Genes and pathways downstream of telomerase in melanoma metastasis.
Genes associated with telomerase activity levels in esophageal carcinoma cell lines.
Genetic alterations in anaplastic thyroid carcinoma and targeted therapies.
Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone.
Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma.
Genetic and epigenetic basis of hepatoblastoma diversity.
Genetic and epigenetic changes in stomach cancer.
Genetic and epigenetic modulation of telomerase activity in development and disease.
Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.
Genetic changes and telomerase activity in human renal cell carcinoma.
Genetic changes associated with telomerase activity in breast cancer.
Genetic control of telomerase and replicative senescence in human and rodent cells.
Genetic diagnostic test of hepatocellular carcinoma by telomerase catalytic subunit mRNA.
Genetic inhibition of telomerase results in sensitization and recovery of breast tumor cells.
Genetic modeling of Ras-induced human rhabdomyosarcoma.
Genetic Mutations in B-Acute Lymphoblastic Leukemia Among African American and European American Children.
Genetic profile and biological implication of PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) in human cancers: an analysis using The Cancer Genome Atlas.
Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome.
Genetic variants in telomere-maintenance genes and bladder cancer risk.
Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population.
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms.
Genistein suppresses the proliferation of telomerase-negative cells.
Genome rearrangements associated with aberrant telomere maintenance.
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.
Genomic amplification patterns of human telomerase RNA gene and C-MYC in liquid-based cytological specimens used for the detection of high-grade cervical intraepithelial neoplasia.
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
Genomic instability and cancer.
Genomic instability is associated with lack of telomerase activation in ovarian cancer.
Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer.
Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT).
Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint.
Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors.
GG sequence of DNA and the human telomeric sequence react with cis-diammine-diaquaplatinum at comparable rates.
Giant-cell tumor of skin with cytoplasmic human telomerase reverse transcriptase expression.
Ginger extract inhibits human telomerase reverse transcriptase and c-Myc expression in A549 lung cancer cells.
Ginger Extract Promotes Telomere Shortening and Cellular Senescence in A549 Lung Cancer Cells.
Gleditsia species: An ethnomedical, phytochemical and pharmacological review.
Glioblastoma induces vascular endothelial cells to express telomerase in vitro.
Glioma: What is the role of c-Myc, hsp90 and telomerase?
Global expression profile of telomerase-associated genes in HeLa cells.
Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen-125 secretion in ovarian carcinoma.
Glutathione regulates telomerase activity in 3T3 fibroblasts.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component.
Gold Nanoprobe Based Label-Free Detection of Human Telomerase Reverse Transcriptase (hTERT) Gene Expression: Gold Nanoprobe-Based Detection of hTERT Gene Expression.
GOLPH3 Promotes Cancer Growth by Interacting With STIP1 and Regulating Telomerase Activity in Pancreatic Ductal Adenocarcinoma.
Graft expression of p38 and tumor necrosis factor-alpha in heart transplantation in rats.
Grainyhead-like 2 as a double-edged sword in development and cancer.
Graphene-Mesoporous Silica-Dispersed Palladium Nanoparticles-Based Probe Carrier Platform for Electrocatalytic Sensing of Telomerase Activity at Less Than Single-Cell Level.
GRIM-19 Restores Cervical Cancer Cell Senescence by Repressing hTERT Transcription.
Growth arrest, apoptosis, and telomere shortening of Barrett's-associated adenocarcinoma cells by a telomerase inhibitor.
Growth Retardation of Poorly Transfectable Tumor by Multiple Injections of plasmids Encoding PE40 Based Targeted Toxin Complexed with Poly-ethylenimine.
GV-1001, an injectable telomerase peptide vaccine for the treatment of solid cancers.
GV1001 interacts with androgen receptor to inhibit prostate cell proliferation in benign prostatic hyperplasia by regulating expression of molecules related to epithelial-mesenchymal transition.
H. pylori induces a novel NF-?B/Lin28A/let-7a/hTERT axis to promote gastric carcinogenesis.
H2O2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage.
HAATI survivors replace canonical telomeres with blocks of generic heterochromatin.
Hallmarks of telomeres in ageing research.
Hammerhead ribozyme-mediated inhibition of telomerase activity in extracts of human hepatocellular carcinoma cells.
Hammerhead ribozymes to modulate telomerase activity of endometrial carcinoma cells.
Haploinsufficiency of hTERT leads to telomere dysfunction and radiosensitivity in human cancer cells.
Harnessing telomerase in cancer therapeutics.
HDAC9 regulates the alternative lengthening of telomere (ALT) pathway via the formation of ALT-associated PML bodies.
Heat shock protein-mediated cell penetration and cytosolic delivery of macromolecules by a telomerase-derived peptide vaccine.
Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells.
Helicobacter pylori infection: augmentation of telomerase activity in cancer and noncancerous tissues.
Heparan Sulfate Proteoglycans Promote Telomerase Internalization and MHC Class II Presentation on Dendritic Cells.
Hepatic angiomyolipoma in a 26-year-old Caucasian woman with a history of tibial osteosarcoma.
Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.
Hepatitis C virus core protein enhances Telomerase activity in Huh7 cells.
Hepatocellular malignant neoplasm, NOS: a clinicopathological study of 11 cases from a single institution.
Herbal complex suppresses telomerase activity in chemo-endocrine resistant cancer cell lines.
Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells.
Herpesvirus telomerase RNA (vTR) with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
Heterogeneity of telomerase reverse transcriptase mutation and expression, telomerase activity and telomere length across human cancer cell lines cultured in vitro.
Heterogeneous nuclear ribonucleoprotein A2/B1 in association with hTERT is a potential biomarker for hepatocellular carcinoma.
Heterozygous telomerase deficiency in mouse and man: when less is definitely not more.
HIF-1-mediated activation of telomerase in cervical cancer cells.
High detection rate of circulating tumor cells in blood of patients with prostate cancer using telomerase activity.
High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab.
High expression of hTERT and stemness genes in BORIS/CTCFL positive cells isolated from embryonic cancer cells.
High expression of human telomerase reverse transcriptase in high-grade intraepithelial neoplasia and carcinoma of uterine cervix and its correlation with human papillomavirus infection.
High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma.
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
High incidence of TERT mutation in brain tumor cell lines.
High in vitro and in vivo antitumor activities of luminecent platinum(II) complexes with jatrorrhizine derivatives.
High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma.
High levels of telomere dysfunction bestow a selective disadvantage during the progression of human oral squamous cell carcinoma.
High performance liquid chromatography with ultraviolet detection for the determination of SYUIQ-5, a novel telomerase inhibitor for cancer therapy: application to an enzyme kinetic study in rat liver microsomes.
High telomerase activity and high HTRT mRNA expression differentiate pure myxoid and myxoid/round-cell liposarcomas.
High telomerase activity and long telomeres in advanced hepatocellular carcinomas with poor prognosis.
High telomerase activity correlates with the stabilities of genome and DNA ploidy in renal cell carcinoma.
High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.
High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer.
High telomerase activity is associated with cell cycle deregulation and rapid progression in endometrioid adenocarcinoma of the uterus.
High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor.
High telomerase RNA expression level is an adverse prognostic factor for favorable-histology Wilms' tumor.
High-throughput analysis of telomerase by capillary electrophoresis.
High-throughput identification of telomere-binding ligands based on the fluorescence regulation of DNA-copper nanoparticles.
High-throughput RNAi screening reveals novel regulators of telomerase.
Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity.
Highly prevalent TERT promoter mutations in aggressive thyroid cancers.
Highly sensitive detection of telomerase activity in tumor cells by cascade isothermal signal amplification based on three-way junction and base-stacking hybridization.
Highly sensitive detection of telomerase based on a DNAzyme strategy.
Highly sensitive detection of telomerase using a telomere-triggered isothermal exponential amplification-based DNAzyme biosensor.
Highly sensitive electrochemical analysis of telomerase activity based on magnetic bead separation and exonuclease III-aided target recycling amplification.
Highly sensitive electrochemical detection of human telomerase activity based on bio-barcode method.
Highly sensitive fluorescence quantification of intracellular telomerase activity by repeat G-rich DNA enhanced silver nanoclusters.
Highly sensitive ratiometric fluorescent paper sensor for the urine assay of cancer.
Highly-sensitive and fast detection of human telomeric G-Quadruplex DNA based on a hemin-conjugated fluorescent metal-organic framework platform.
Histamine amplifies immune response of gingival fibroblasts.
Histone Acetylation and Retinoic Acid Receptor beta DNA Methylation as Novel Targets for Gastric Cancer Therapy.
Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells.
Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast.
Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention.
HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex.
HIV-Tat-mediated Delivery of an LPTS Functional Fragment Inhibits Telomerase Activity and Tumorigenecity of Hepatoma Cells.
HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction.
Hodgkin and Reed-Sternberg cells of classical Hodgkin's disease overexpress the telomerase RNA template (hTR).
Homogeneous and ultrasensitive detection of telomerase activity via gold nanorod-based fluorescence resonance energy transfer.
Homogeneous Electrochemical Strategy for Human Telomerase Activity Assay at Single-Cell Level Based on T7 Exonuclease-Aided Target Recycling Amplification.
Homology Model and Docking-Based Virtual Screening for Ligands of Human Dyskerin as New Inhibitors of Telomerase for Cancer Treatment.
Hormones and growth factors regulate telomerase activity in ageing and cancer.
Host immune responses to chlamydial inclusion membrane proteins B and C in Chlamydia trachomatis infected women with or without fertility disorders.
Hot Spot TERT Promoter Mutations Are Rare in Sporadic Pancreatic Neuroendocrine Neoplasms and Associated with Telomere Length and Epigenetic Expression Patterns.
HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.
Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.
How and why we age.
How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle.
How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?
How to inhibit telomerase activity for cancer therapy.
How will telomeric complex be further contributed to our longevity? - the potential novel biomarkers of telomere complex counteracting both aging and cancer.
HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a.
HPV E6 protein interacts physically and functionally with the cellular telomerase complex.
HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR Assay for Detecting High-Grade Cervical Lesion with Microscope Slides.
HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function.
HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma.
Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.
hTERT and BIRC5 gene promoters for cancer gene therapy: A comparative study.
hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer.
hTERT cancer risk genotypes are associated with telomere length.
hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells.
hTERT expression and prognosis in B-chronic lymphocytic leukemia.
htert expression correlates with MYC over-expression in human prostate cancer.
hTERT expression in sporadic renal cell carcinomas.
hTERT gene copy number is not associated with hTERT RNA expression or telomerase activity in colorectal cancer.
hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines.
Htert gene expression levels and telomerase activity in drug resistant mcf-7 cells.
hTERT is a critical determinant of telomerase activity in renal-cell carcinoma.
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site.
hTERT Is highly expressed in Ewing's sarcoma and activated by EWS-ETS oncoproteins.
hTERT mediates gastric cancer metastasis partially through the indirect targeting of ITGB1 by microRNA-29a.
hTERT mediates norepinephrine-induced Slug expression and ovarian cancer aggressiveness.
hTERT methylation and expression in gastric cancer.
hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells.
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes.
HTERT mRNA expression correlates with matrix metalloproteinase-1 and vascular endothelial growth factor expression in human breast cancer: a correlative study using RT-PCR.
hTERT mRNA expression correlates with telomerase activity in human breast cancer.
HTERT mRNA partially regulates telomerase activity in gastric adenocarcinoma and adjacent normal gastric mucosa.
hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms.
hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells.
hTERT promoter activity identifies osteosarcoma cells with increased EMT characteristics.
hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity.
hTERT promoter methylation promotes small cell lung cancer progression and radiotherapy resistance.
hTERT promoter methylation status in peripheral blood leukocytes as a molecular marker of head and neck cancer progression.
hTERT promotes cell adhesion and migration independent of telomerase activity.
hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation.
hTERT promotes the invasion of telomerase-negative tumor cells in vitro.
hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factor.
hTERT promotes tumor progression by enhancing TSPAN13 expression in osteosarcoma cells.
hTERT regulation by NF-?B and c-myc in irradiated HER2-positive breast cancer cells.
hTERT-based therapy: a universal anticancer approach (Review).
hTERT-promoter driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletions.
hTERT/re-caspase-3 system induce apoptosis in hTERT-positive cancer cells.
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
hTERT: Another brick in the wall of cancer cells.
HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene.
HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).
hTR repressor-related gene on human chromosome 10p15.1.
Human ageing and telomeres.
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.
Human cancer cells harbor T-stumps, a distinct class of extremely short telomeres.
Human cathelicidin peptide LL37 binds telomeric G-quadruplex.
Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer.
Human chromosome 5 carries a putative telomerase repressor gene.
Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors.
Human epithelial cell immortalization as a step in carcinogenesis.
Human fibroblasts from normal and malignant breast tissue grown in vitro show a distinct senescence profile and telomerase activity.
Human genetic variations: Beacons on the pathways to successful ageing.
Human Ku70/80 associates physically with telomerase through interaction with hTERT.
Human lymphocyte telomerase is genetically regulated.
Human mammaglobin: a superior marker for reverse-transcriptase PCR in detecting circulating tumor cells in breast cancer patients.
Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy.
Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma.
Human sarcomas are mosaic for telomerase-dependent and telomerase-independent telomere maintenance mechanisms: implications for telomere-based therapies.
Human T cell leukemia virus type II increases telomerase activity in uninfected CD34+ hematopoietic progenitor cells.
Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase.
Human telomerase activity regulation.
Human telomerase and alpha-methylacyl-coenzyme A racemase in prostatic carcinoma. A comparative immunohistochemical study.
Human telomerase and its regulation.
Human telomerase caught in the act.
Human telomerase expression regulation.
Human telomerase gene amplification and high-risk human papillomavirus infection in women with cervical intra-epithelial neoplasia.
Human Telomerase Gene and High-Risk Human Papillomavirus Infection are Related to Cervical Intraepithelial Neoplasia.
Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates.
Human telomerase inhibitors from microbial source
Human telomerase inhibitors from microbial source.
Human telomerase represses ROS-dependent cellular responses to Tumor Necrosis Factor-? without affecting NF-?B activation.
Human telomerase reverse transcriptase (hTERT) expression in borderline ovarian tumors: an immunohistochemical study.
Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasms.
Human telomerase reverse transcriptase (hTERT) gene expression in thyroid carcinoma: diagnostic and prognostic role.
Human Telomerase Reverse Transcriptase (hTERT) Positively Regulates 26S Proteasome Activity.
Human telomerase reverse transcriptase (hTERT) promotes cancer invasion by modulating cathepsin D via early growth response (EGR)-1.
Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression.
Human telomerase reverse transcriptase (hTERT): a target molecule for the treatment of cisplatin-resistant tumors.
Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis.
Human telomerase reverse transcriptase antisense treatment downregulates the viability of prostate cancer cells in vitro.
Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues.
Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells.
Human telomerase reverse transcriptase expression correlates with vascular endothelial growth factor-promoted tumor cell proliferation in prostate cancer.
Human telomerase reverse transcriptase expression in ovarian tumors.
Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.
Human telomerase reverse transcriptase is a novel target of Hippo-YAP pathway.
Human telomerase reverse transcriptase is a promising target for cancer inhibition in squamous cell carcinomas.
Human telomerase reverse transcriptase messenger RNA (TERT mRNA) as a tumour marker for early detection of hepatocellular carcinoma.
Human telomerase reverse transcriptase promoter regulation in normal and malignant human ovarian epithelial cells.
Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma.
Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-?B-dependent transcription.
Human telomerase reverse transcriptase regulation by DNA methylation, transcription factor binding and alternative splicing (Review).
Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes.
Human telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment.
Human telomerase RNA accumulation in cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation.
Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal.
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues.
Human telomerase RNA as endogenous control in endometrial tissue.
Human telomerase RNA component (hTERC) gene expression and chromosome 7 ploidy correlate positively with histological grade of cervical intraepithelial neoplasia.
Human telomerase RNA degradation by 2'-5'-linked oligoadenylate antisense chimeras in a cell-free system, cultured tumor cells, and murine xenograft models.
Human telomerase RNA expression and MIB-1 (Ki-67) proliferation index distinguish hemangioblastomas from metastatic renal cell carcinomas.
Human telomerase RNA gene amplification detection increases the specificity of cervical intraepithelial neoplasia screening.
Human Telomerase RNA: Telomerase Component or More?
Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition.
Human telomeric G-quadruplex: the current status of telomeric G-quadruplexes as therapeutic targets in human cancer.
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.
Human TERT promoter polymorphism rs2853669 is associated with cancers: an updated meta-analysis.
Hybrids Based on Graphene Oxide and Porphyrin as Tools for Detection and Stabilization of DNA G-Quadruplexes.
Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation.
Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model.
Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through downregulation of E2A-p21 by HIF-TWIST.
Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming.
Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells.
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).
Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms.
ICAM-5 (telencephalin) gene expression in head and neck squamous carcinoma tumorigenesis and perineural invasion!
Identification and functional characterization of nuclear mortalin in human carcinogenesis.
Identification of a gene cluster for telomestatin biosynthesis and heterologous expression using a specific promoter in a clean host.
Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells.
Identification of a New Cytotoxic T-Cell Epitope p675 of Human Telomerase Reverse Transcriptase.
Identification of a novel co-transcription of P450/1A1 with telomerase in A549.
Identification of a potential human telomerase reverse transcriptase-derived, HLA-A1-restricted cytotoxic T-lymphocyte epitope.
Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells.
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly.
Identification of genes involved in the regulation of TERT in hepatocellular carcinoma.
Identification of HLA DR7-restricted epitopes from human telomerase reverse transcriptase recognized by CD4+ T-helper cells.
Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging.
Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.
Identification of human telomerase inhibitors having the core of N-acyl-4,5-dihydropyrazole with anticancer effects.
Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes.
Identification of IDH and TERTp mutation status using 1 H-MRS in 112 hemispheric diffuse gliomas.
Identification of key processes underlying cancer phenotypes using biologic pathway analysis.
Identification of Mad as a repressor of the human telomerase (hTERT) gene.
Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach.
Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq.
Identification of PITX1 as a TERT Suppressor Gene Located on Human Chromosome 5.
Identification of small molecule inhibitors of telomerase activity through transcriptional regulation of hTERT and calcium induction pathway in human lung adenocarcinoma A549 cells.
Identification of zebrafish LPTS: a gene with similarities to human LPTS/PinX1 that inhibits telomerase activity.
Identifying and Targeting the Cause of Cancer is Needed to Cure Cancer.
Identifying G-quadruplex-binding ligands using DNA-functionalized gold nanoparticles.
IFN-gamma/IRF-1-induced p27kip1 down-regulates telomerase activity and human telomerase reverse transcriptase expression in human cervical cancer.
IgG1-iS18 impedes the adhesive and invasive potential of early and late stage malignant melanoma cells.
Imaging Mass Spectrometry and Proteome Analysis of Marek's Disease Virus-Induced Tumors.
Imetelstat (a telomerase antagonist) exerts off?target effects on the cytoskeleton.
Imetelstat (GRN163L)--telomerase-based cancer therapy.
Imetelstat, a telomerase inhibitor, differentially affects normal and malignant megakaryopoiesis.
Immortal ALT+ human cells do not require telomerase reverse transcriptase for malignant transformation.
Immortal and mortal clonal lymphocyte lines from channel catfish: comparison of telomere length, telomerase activity, tumor suppressor and heat shock protein expression.
Immortal phenotype of the esophageal epithelial cells in the process of immortalization.
Immortality of cancers: A consequence of inherent karyotypic variations and selections for autonomy.
Immortalization of epithelial progenitor cells mediated by resveratrol.
Immortalization of human AE pre-leukemia cells by hTERT allows leukemic transformation.
Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.
Immortalized bovine mammary epithelial cells express stem cell markers and differentiate in vitro.
Immortalized cells as experimental models to study cancer.
Immortalized mouse mammary cells in vivo do not exhibit increased telomerase activity.
Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma: tumor size and lymph node status remain the most important prognostic features.
Immunization of patients with the hTERT:540-548 peptide induces peptide-reactive T lymphocytes that do not recognize tumors endogenously expressing telomerase.
Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.
Immunodetection and clinico-pathological correlates of two tumour growth regulators in laryngeal carcinoma.
Immunogenic HLA-B*0702-restricted epitopes derived from human telomerase reverse transcriptase that elicit antitumor cytotoxic T-cell responses.
Immunogenic HLA-B7-restricted peptides of hTRT.
Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice.
Immunogenicity of gx301 cancer vaccine: Four (telomerase peptides) is better than one.
Immunohistochemical and molecular study of radiation-induced multiple meningiomas with pleural and pulmonary metastasis.
Immunohistochemical detection of hTERT in urothelial lesions: a potential adjunct to urine cytology.
Immunohistochemical detection of hTERT protein in soft tissue sarcomas: correlation with tumor grade.
Immunohistochemical detection of human telomerase reverse transcriptase in normal mucosa and precancerous lesions of the stomach.
Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue.
Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues.
Immunohistochemical detection of telomerase reverse transcriptase (TERT) protein in benign and malignant tumor cells of the breast.
Immunohistochemical detection of telomerase reverse transcriptase in colorectal adenocarcinoma and benign colonic mucosa.
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Immunohistochemical evaluation of salivary gland tumors differentiation and proliferation by using calponin and telomerase.
Immunohistochemical expression of proliferative markers in renal cell carcinoma.
Immunohistochemical expression of ubiquitin and telomerase in cervical cancer.
Immunohistochemical localization of hTERT protein in human tissues.
Immunohistochemical localization of telomerase hTERT protein and analysis of clonality in multifocal vulvar intraepithelial neoplasia.
Immunohistochemical localization of telomerase in myomas and in uterine myometrium.
Immunohistochemical Profiling and Telomerase Activity of a Canine Medulloblastoma.
Immunohistochemistry for human telomerase reverse transcriptase catalytic subunit (hTERT): a study of 143 benign and malignant soft tissue and bone tumours.
Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors.
Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients.
Immunotherapeutic effects of cytokine-induced killer cells combined with CCL21/IL15 armed oncolytic adenovirus in TERT-positive tumor cells.
Immunotherapy of tumors with human telomerase reverse transcriptase immortalized human umbilical vein endothelial cells.
Impact of modulation of telomerase and cancer stem-cell marker OCT4 axis in cervical cancer pathogenesis with underlying HPV16 infection.
Impact of oxidative stress on telomere biology.
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.
Impaired telomere maintenance in Alazami syndrome patients with LARP7 deficiency.
Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice.
Implication of human telomerase reverse transcriptase in cervical carcinogenesis and cancer recurrence.
Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas.
Implication of telomerase activity and alternations of telomere length in the histologic characteristics of intracranial meningiomas.
Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase.
Implications of prognostic markers in brain tumors.
Implications of telomerase reverse transcriptase in tumor metastasis.
Implications of telomere-independent activities of telomerase reverse transcriptase in human cancer.
Implications of telomeres and telomerase in endometrial pathology.
Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.
Improved cryopreservation of human embryonic stem cells with trehalose.
Improved methods and standards for telomerase detection: quantitative histopathology using antibody staining.
In perspective: An update on telomere targeting in cancer.
In silico evaluation of TERT inhibition by anticancer drugs.
In silico screening of herbal and nanoparticle lead compounds for effectivity against H5N1, H1N1 neuraminidase and telomerase.
In situ Analysis of Cancer Cells Based on DNA Signal Amplification and DNA Nanodevices.
In situ analysis of telomerase RNA gene expression as a marker for tumor progression.
In Situ Detection and Imaging of Telomerase Activity in Cancer Cell Lines via Disassembly of Plasmonic Core-Satellites Nanostructured Probe.
In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma.
In situ detection of telomerase catalytic subunit mRNA in glioblastoma multiforme.
In situ detection of telomerase enzymatic activity in human hepatocellular carcinogenesis.
In situ fluorescence monitoring of diagnosis and treatment: a versatile nanoprobe combining tumor targeting based on MUC1 and controllable DOX release by telomerase.
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
In situ hybridization for telomerase RNA in routine cytologic brushings for the diagnosis of pancreaticobiliary malignancies.
In situ hybridization for the detection of telomerase RNA in the progression from Barrett's esophagus to esophageal adenocarcinoma.
In situ imaging of intracellular human telomerase RNA with molecular beacon-functionalized gold nanoparticles.
In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions.
In situ nucleic acid detection of human telomerase in intrahepatic cholangiocarcinoma and its preneoplastic lesion.
In situ telomerase activity in pancreatic juice may discriminate pancreatic cancer from other pancreatic diseases.
In situ telomerase activity in pleural effusions: a promising marker for malignancy.
In situ visualization of telomere elongation patterns in human cells.
In Situ Visualization of Telomere Length, Telomere Elongation, and TERT Expression in Single Cells.
In this issue: Proteomics 3/2009.
In utero nucleoside reverse transcriptase inhibitor exposure and cancer in HIV-uninfected children: an update from the pediatric AIDS clinical trials group 219 and 219C cohorts.
In vitro activation of cytotoxic T-lymphocytes by hTERT-pulsed dendritic cells.
In vitro and in vivo tumor suppressive activity induced by human telomerase transcriptase-targeting antisense oligonucleotides mediated by cationic liposomes.
In vitro anti-tumor immune response induced by dendritic cells transfected with hTERT recombinant adenovirus.
In Vitro Assessment of the Expression and T Cell Immunogenicity of the Tumor-Associated Antigens BORIS, MUC1, hTERT, MAGE-A3 and Sp17 in Uterine Cancer.
In vitro effects on proliferation, telomerase activity and apoptosis of an eremophilanoid sesquiterpene from Senecio oldhamianus maxim in cultured human tumor cell lines.
In vitro Evaluation of the Therapeutic Potential of Nevirapine in Treatment of Human Thyroid Anaplastic Carcinoma.
In vitro modulation of telomerase activity, telomere length and cell cycle in MKN45 cells by verbascoside.
In vitro quantification of the cytotoxic T lymphocyte response against human telomerase reverse transcriptase in breast cancer.
In vitro transformation of mesenchymal stem cells induces gradual genomic hypomethylation.
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.
In vivo biological purging for lymph node metastasis of human colorectal cancer by telomerase-specific oncolytic virotherapy.
In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor.
In vivo reprogramming of human telomerase reverse transcriptase (hTERT) by trans-splicing ribozyme to target tumor cells.
In-situ hybridization-based quantification of hTR: a possible biomarker in malignant melanoma.
Inactivation of hTERT transcription by Tax.
Inactivation of p16INK4 in hepatocellular carcinoma.
Inactive C-terminal telomerase reverse transcriptase insertion splicing variants are dominant-negative inhibitors of telomerase.
Incidence of cancer in children perinatally exposed to nucleoside reverse transcriptase inhibitors.
Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas.
Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells.
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.
Increased expression of miR-222 is associated with poor prognosis in bladder cancer.
Increased expression of telomerase RNA component is associated with increased cell proliferation in human astrocytomas.
Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia.
Increased gap junctional intercellular communication is directly related to the anti-tumor effect of all-trans-retinoic acid plus tamoxifen in a human mammary cancer cell line.
Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation.
Increased safety with preserved antitumoral efficacy on hepatocellular carcinoma with dual-regulated oncolytic adenovirus.
Increased sensitivity and reproducibility of TRAP assay by avoiding direct primers interaction.
Increased telomerase activities in human pancreatic duct adenocarcinomas.
Increased telomerase activity and absence of p53 mutation in oligoastrocytomas induced by N-ethyl-N-nitrosourea in rats.
Increased telomerase activity and comprehensive lifestyle changes: a pilot study.
Increased telomerase activity and decreased telomere length in genital condylomata acuminata.
Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung.
Increased telomerase activity and hTERT expression in human salivary gland carcinomas.
Increased telomerase activity in hyperplastic nodules and hepatocellular carcinomas induced by a choline-deficient L-amino acid-defined diet in rats.
Increased telomerase activity in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Increased telomerase activity in mouse skin premalignant progression.
Increased TERC gene copy number and cells in senescence in primary sclerosing cholangitis compared to colitis and control patients.
Increased TERC gene copy number in amniocytes from fetuses with trisomy 18 or a sex chromosome aneuploidy.
Increased TERRA levels and RNase H sensitivity are conserved hallmarks of post-senescent survivors in budding yeast.
Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices.
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.
Increasing sensitivity to arsenic trioxide-induced apoptosis by altered telomere state.
Individual susceptibility to DNA telomerase inhibitors: a study on the chromosome instability induced by 3'-azido-3'-deoxythymidine in lymphocytes of elderly twins.
Indomethacin and telomerase activity in tumor growth retardation.
Indomethacin suppresses the growth of colon 26, Meth-A and FM3A tumors in mice by reducing the prostaglandin E2 content and telomerase activity in tumor tissues.
Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres.
Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.
Inducible immortality in hTERT-human mesenchymal stem cells.
Induction of apoptosis and inhibition of telomerase activity in human bone marrow and HL-60 p53 null cells treated with anti-cancer drugs.
Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.
Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.
Induction of DNA damage and apoptosis in human leukemia cells by efavirenz.
Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements.
Induction of nephroblastoma by myeloblastosis-associated virus type 1: state of proviral DNAs in tumor cells.
Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells.
Induction of ovarian cancer cell apoptosis by 1,25-dihydroxyvitamin D3 through the down-regulation of telomerase.
Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA.
Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity.
Induction of telomerase activity and chromosome aberrations in human tumour cell lines following X-irradiation.
Induction of telomerase activity by irradiation in human lymphoblasts.
Induction of telomerase activity by UV-irradiation in Chinese hamster cells.
Induction of telomerase activity during development of human mast cells from peripheral blood CD34+ cells: comparisons with tumor mast-cell lines.
Induction of telomerase activity in avian lymphoblastoid cell line transformed by Marek's disease virus, MDCC-MSB1.
Induction of telomerase activity in stimulated human lymphocytes precedes expression of topoisomerase II alpha.
Induction of telomerase activity in v-myc-transformed avian cells.
Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma.
Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment.
Influence of Human Telomerase Reverse Transcriptase Mutation on the Aggressiveness and Recurrence in Meningiomas.
Influence of small interfering RNA corresponding to ets homologous factor on senescence-associated modulation of prostate carcinogenesis.
Influence of telomerase activity on bone and soft tissue tumors.
Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome.
Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells.
Inhibition of canine telomerase in vitro and in vivo using RNAi: further development of a natural canine model for telomerase-based cancer therapies.
Inhibition of cell growth and telomerase activity in osteosarcoma cells by DN-hTERT.
Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by retinoic acids.
Inhibition of cell growth by cellular differentiation into adipocyte-like cells in dexamethasone sensitive cancer cell lines.
Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells.
Inhibition of hTERT Gene Expression by Silibinin-Loaded PLGA-PEG-Fe3O4 in T47D Breast Cancer Cell Line.
Inhibition of human telomerase activity by antisense phosphorothioate oligonucleotides encapsulated with the transfection reagent, FuGENE6, in HeLa cells.
Inhibition of human telomerase by 2'-O-methyl-RNA.
Inhibition of human telomerase by a retrovirus expressing telomeric antisense RNA.
Inhibition of human telomerase by oligonucleotide chimeras, composed of an antisense moiety and a chemically modified homo-oligonucleotide.
Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety.
Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells.
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death.
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
Inhibition of human telomerase reverse transcriptase in vivo and in vitro for retroviral vector-based antisense oligonucleotide therapy in ovarian cancer.
Inhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instability.
Inhibition of proliferation and induction of apoptosis in human renal carcinoma cells by anti-telomerase small interfering RNAs.
Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines.
Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells.
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.
Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes.
Inhibition of telomerase activity as a measure of tumor cell killing by cisplatin in squamous cell carcinoma cell line.
Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells.
Inhibition of telomerase activity by a hammerhead ribozyme targeting the RNA component of telomerase in human melanoma cells.
Inhibition of telomerase activity by cisplatin in human testicular cancer cells.
Inhibition of telomerase activity by dominant-negative hTERT retards the growth of breast cancer cells.
Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells.
Inhibition of telomerase activity by HDV ribozyme in cancers.
Inhibition of telomerase activity by NME2: impact on metastasis suppression?
Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture.
Inhibition of telomerase activity by preventing proper assemblage.
Inhibition of telomerase activity correlates with a decrease in the RNA component of telomerase during differentiation.
Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization.
Inhibition of telomerase activity in cancer cells using short hairpin RNA expression vectors.
Inhibition of telomerase activity in endometrial cancer cells by selenium-cisplatin conjugate despite suppression of its DNA-damaging activity by sodium ascorbate.
Inhibition of telomerase activity in human cancer cells by RNA interference.
Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide.
Inhibition of telomerase activity in renal cell carcinoma cells by doxorubicin and anti-Fas monoclonal antibody.
Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer.
Inhibition of telomerase by 2'-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells.
Inhibition of telomerase by site-specific ribonucleases in gastric and esophageal adenocarcinoma.
Inhibition of telomerase in canine cancer cells following telomestatin treatment.
Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts.
Inhibition of telomerase in tumor cells by ribozyme targeting telomerase RNA component.
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis.
Inhibition of telomerase induces alternative lengthening of telomeres during human esophageal carcinogenesis.
Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells.
Inhibition of telomerase limits the growth of human cancer cells.
Inhibition of Telomerase Recruitment and Cancer Cell Death.
Inhibition of telomerase RNA (hTR) in cervical cancer by adenovirus-delivered siRNA.
Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.
Inhibition of telomerase with human telomerase reverse transcriptase antisense enhances tumor necrosis factor-alpha-induced apoptosis in bladder cancer cells.
Inhibition of telomerase with human telomerase reverse transcriptase antisense increases the sensitivity of tumor necrosis factor-alpha-induced apoptosis in prostate cancer cells.
Inhibition of the alternative lengthening of telomeres pathway by subtelomeric sequences in Saccharomyces cerevisiae.
Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells.
Inhibition of tumour virus RNA-dependent DNA polymerase by the heteropolyan ion, silicotungstate.
Inhibition of tumour virus RNA-dependent DNA polymerase by the heteropolyanion, silicotungstate.
Inhibition of UBE2D3 expression attenuates radiosensitivity of MCF-7 human breast cancer cells by increasing hTERT expression and activity.
Inhibitor of the human telomerase reverse trancriptase (hTERT) gene promoter induces cell apoptosis via a mitochondrial-dependent pathway.
Inhibitory effect and mechanisms of microRNA-146b-5p on the proliferation and metastatic potential of Caski human cervical cancer cells.
Inhibitory effect of human telomerase antisense oligodeoxyribonucleotides on the growth of gastric cancer cell lines in variant tumor pathological subtype.
Inhibitory effect of telomere-mimic phosphorothioate oligodeoxy nucleotides (S-ODNS) on human tumor cell lines.
Inhibitory effects of dietary protocatechuic acid and costunolide on 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.
Inhibitory role of transcription factor COUP-TFII in expression of hTERT in HeLa cells.
Insights into Telomerase/hTERT Alternative Splicing Regulation Using Bioinformatics and Network Analysis in Cancer.
Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres.
Insufficient PINX1 expression stimulates telomerase activation by direct inhibition of EBV LMP1-NF-?B axis during nasopharyngeal carcinoma development.
Insulin-like growth factor 2 and its receptors (IGF 1R and IGF 2R/mannose 6-phosphate) in endometrial adenocarcinoma.
Insulin-like growth factor I stimulates telomerase activity in prostate cancer cells.
Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation.
Integrated evaluation of telomerase activation and telomere maintenance across cancer cell lines.
Integrated nanoparticle-biomolecule systems for biosensing and bioelectronics.
Integrated nanosensors to determine levels and functional activity of human telomerase.
Integration of intracellular telomerase monitoring by electrochemiluminescence technology and targeted cancer therapy by reactive oxygen species.
Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers.
Integrator is a key component of human telomerase RNA biogenesis.
Intensive Inhibition of hTERT Expression by a Ribozyme Induces Rapid Apoptosis of Cancer Cells through a Telomere Length-Independent Pathway.
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Interaction between Gambogic acid and dihydrofolate reductase and synergistic lethal effects with methotrexate on hepatoma cells.
Interaction between human telomere and a carbazole derivative: a molecular dynamics simulation of a quadruplex stabilizer and telomerase inhibitor.
Interaction of an acridine dimer with DNA quadruplex structures.
Interaction of deoxyguanosine nucleotide analogs with human telomerase.
Interaction of G-quadruplexes with nonintercalating duplex-DNA minor groove binding ligands.
Interaction studies of carbon nanomaterials and plasma activated carbon nanomaterials solution with telomere binding protein.
Interactions of ruthenium complexes containing indoloquinoline moiety with human telomeric G-quadruplex DNA.
Interchromosomal homology searches drive directional ALT telomere movement and synapsis.
Interference of cytokeratin-20 and mammaglobin-reverse-transcriptase polymerase chain assays designed for the detection of disseminated cancer cells.
Interferon regulatory factor-1 (IRF-1) is a mediator for interferon-gamma induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression.
Interferon-alpha repressed telomerase along with G1-accumulation of Daudi cells.
Interleukin 10 prevents necrosis in murine experimental acute pancreatitis.
Interleukin 8 is a biomarker of telomerase inhibition in cancer cells.
Interleukin-6 decreases senescence and increases telomerase activity in malignant human cholangiocytes.
Interphase detection of t(4;14)(p16.3;q32.3) by in situ hybridization and FGFR3 overexpression in plasma cell malignancies.
Interplay between TERT promoter mutations and methylation culminates in chromatin accessibility and TERT expression.
InTERTesting association between telomerase, mTOR and phytochemicals.
InTERTpreting telomerase structure and function.
Interweaving MicroRNAs and Proinflammatory Cytokines in Gastric Mucosa with Reference to H. pylori Infection.
Intra-peritoneal administration of genetic therapies: promises and pitfalls.
Intranasal tumor of the ethmoid olfactory mucosa in sheep.
Intraoperative bacterial translocation detected by bacterium-specific ribosomal rna-targeted reverse-transcriptase polymerase chain reaction for the mesenteric lymph node strongly predicts postoperative infectious complications after major hepatectomy for biliary malignancies.
Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination.
Introduction of p16INK4a inhibits telomerase activity through transcriptional suppression of human telomerase reverse transcriptase expression in human gliomas.
Introduction to telomeres and telomerase.
Intron 4-5 hTERT DNA Hypermethylation in Merkel Cell Carcinoma: Frequency, Association with Other Clinico-pathological Features and Prognostic Relevance.
Invasion of normal human fibroblasts induced by v-Fos is independent of proliferation, immortalization, and the tumor suppressors p16INK4a and p53.
Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.
Investigating the Effects of RBBP6 Gene Expression on Telomerase Activity in Cervical Cancer Cells.
Investigating the impact of local inflammation on granulosa cells and follicular development in women with ovarian endometriosis.
Investigating the Role of Telomere and Telomerase Associated Genes and Proteins in Endometrial Cancer.
Investigation of telomerase activity and apoptosis on invasive ductal carcinoma of the breast using immunohistochemical and Western blot methods.
Investigation of the effect of telomerase inhibitor BIBR1532 on breast cancer and breast cancer stem cells.
Involvement of 14-3-3 proteins in nuclear localization of telomerase.
Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination.
Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles.
Involvement of the NFX1-repressor complex in PKC-?-induced repression of hTERT transcription.
Involvement of topoisomerase III in telomere-telomere recombination.
Ionizing radiation up-regulates telomerase activity in cancer cell lines by post-translational mechanism via ras/phosphatidylinositol 3-kinase/Akt pathway.
Irreversible telomere shortening by 3'-azido-2',3'-dideoxythymidine (AZT) treatment.
Is small cell lung cancer the perfect target for anti-telomerase treatment?
Is telomerase a universal cancer target?
Is telomerase a viable target in cancer?
Is telomerase activity in cancer due to selection of stem cells and differentiation arrest?
Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer?
Is the telomerase assay useful for screening of endometrial lesions?
Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed toward the widely expressed tumor T-cell epitopes of the telomerase catalytic subunit.
Isolation and characterization of RNA-directed DNA polymerase from a B-type RNA tumor virus.
Isolation and expression of the reverse transcriptase component of the Canis familiaris telomerase ribonucleoprotein (dogTERT).
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
Isothiazolone derivatives selectively inhibit telomerase from human and rat cancer cells in vitro.
It all comes together at the ends: Telomerase structure, function, and biogenesis.
Jaagsiekte Sheep Retrovirus (JSRV): from virus to lung cancer in sheep.
Japanese medaka: A new vertebrate model for studying telomere and telomerase biology.
Joint quantitative measurement of hTERT mRNA in both peripheral blood and circulating tumor cells of patients with nasopharyngeal carcinoma and its clinical significance.
Juglans mandshurica Maxim extracts exhibit antitumor activity on HeLa cells in vitro.
Keeping those telomeres short! an innovative intratumoral long-term drug delivery system.
KI-67 AND hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma.
Kinetic evidence for interaction of TMPyP4 with two different G-quadruplex conformations of human telomeric DNA.
Kinetics of DNA replication and telomerase reaction at a single-seeded telomere in human cells.
Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity.
Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer.
Knockdown of apoptosis-inducing factor disrupts function of respiratory complex I.
Knockdown of hTERT Alters Biophysical Properties of K562 Cells Resulting in Decreased Migration Rate In Vitro.
Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell lines.
Knockdown of hTERT by siRNA inhibits cervical cancer cell growth in vitro and in vivo.
Knockdown of human telomerase reverse transcriptase induces apoptosis in cervical cancer cell line.
Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference.
Knockdown of telomeric repeat binding factor 2 enhances tumor radiosensitivity regardless of telomerase status.
Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC.
Kruppel-Like Factor 9 Loss-of-Expression in Human Endometrial Carcinoma Links Altered Expression of Growth-Regulatory Genes with Aberrant Proliferative Response to Estrogen.
Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells.
Ku70 prevents genome instability resulting from heterozygosity of the telomerase RNA component in a vertebrate tumour line.
Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy.
Label-Free Detection of Telomerase Activity in Urine Using Telomerase-Responsive Porous Anodic Alumina Nanochannels.
Label-free detection of telomerase activity using guanine electrochemical oxidation signal.
Label-free electrochemical selection of G-quadruplex-binding ligands based on structure switching.
Label-free electrochemiluminescence biosensor for ultrasensitive detection of telomerase activity in HeLa cells based on extension reaction and intercalation of Ru(phen)3 (2.).
Label-free highly sensitive detection of telomerase activity in cancer cell by chemiluminescence imaging.
Label-free molecular beacons-based cascade amplification DNA machine for sensitive detection of telomerase activity.
Label-Free Telomerase Activity Detection via Electrochemical Impedance Spectroscopy.
Label-Free Telomerase Detection in Single Cell Using a Five-Base Telomerase Product-Triggered Exponential Rolling Circle Amplification Strategy.
Label-free, PCR-free chip-based detection of telomerase activity in bladder cancer cells.
Lack of evidence for the involvement of type-C and type-B retroviruses in radiation leukemogenesis of NFS mice.
Lack of major genome instability in tumors of p53 null rats.
Lack of telomerase activity in human mesenchymal stem cells.
Lack of telomerase activity in lung carcinoids is dependent on human telomerase reverse transcriptase transcription and alternative splicing and is associated with long telomeres.
Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters.
Lack of telomerase in desmoids occurring sporadically and in association with familial adenomatous polyposis.
Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter.
Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.
Latent membrane protein 1 encoded by Epstein-Barr virus induces telomerase activity via p16INK4A/Rb/E2F1 and JNK signaling pathways.
Letter: Parasagittal/Falcine Tumor Location Strongly Predicts Human Telomerase Reverse Transcriptase Promoter Mutations in High-Grade Meningiomas.
Levels of telomerase catalytic subunit mRNA as a predictor of potential malignancy.
Life and cancer without telomerase.
Life and cancer without telomerase: ALT and other strategies for making sure ends (don't) meet.
Life and Death of Yeast Telomerase RNA.
Life at the End of the Chromosome: Telomeres and Telomerase.
Limitations in improving detection of pancreatic adenocarcinoma.
Limitations of detection of malignancy in pleural effusions using ELISA-based TRAP assay: comparison with cytological examination.
Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.
Limitations of urinary telomerase activity measurement in urothelial cancer.
Limitations on the quantitative determination of telomerase activity by the electrophoretic and ELISA based TRAP assays.
LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines.
Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.
Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab.
Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres.
LncRNA FOXD2-AS1 Functions as a Competing Endogenous RNA to Regulate TERT Expression by Sponging miR-7-5p in Thyroid Cancer.
Lobe-specific telomerase activity in the intact adult brown Norway rat prostate and its regional distribution within the prostatic ducts.
Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body.
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Long telomeres are preferentially extended during recombination-mediated telomere maintenance.
Long telomeres bypass the requirement for telomere maintenance in human tumorigenesis.
Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
Long-range telomere regulation of gene expression: Telomere looping and telomere position effect over long distances (TPE-OLD).
Long-term effects of short hairpin RNA-targeted human telomerase reverse transcriptase on suppression of SGC-7901 cell proliferation by inhibition of telomerase activity.
Long-term exposure to MST-312 leads to telomerase reverse transcriptase overexpression in MCF-7 breast cancer cells.
Long-term in vitro expansion of human adipose-derived stem cells showed low risk of tumourigenicity.
Long-term in vitro treatment with telomerase inhibitor MST-312 induces resistance by selecting long telomeres cells.
Long-Term Outcomes of a Phase I Study With UV1, a Second Generation Telomerase Based Vaccine, in Patients With Advanced Non-Small Cell Lung Cancer.
Long-term self-maintenance of hemopoietic precursors in bone marrow culture derived from tumor necrosis factor-deficient mice is not a result of neoplastic transformation.
Loop flexibility in human telomeric quadruplex small-molecule complexes.
Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies.
Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.
Loss of heterozygosity and histone hypoacetylation of the PINX1 gene are associated with reduced expression in gastric carcinoma.
Loss of heterozygosity and human telomerase reverse transcriptase (hTERT) expression in bronchial mucosa of heavy smokers.
Loss of heterozygosity at chromosome 3p correlates with telomerase activity in renal cell carcinoma.
Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.
Loss of telomeric DNA during aging may predispose cells to cancer (review).
Loss of the human polycomb group protein BMI1 promotes cancer-specific cell death.
LOSS OF THE MALIGNANT PHENOTYPE OF HUMAN NEUROBLASTOMA CELLS BY A CATALYTICALLY INACTIVE DOMINANT-NEGATIVE hTERT MUTANT.
Loss of the tumor suppressor STAG2 promotes telomere recombination and extends the replicative lifespan of normal human cells.
Low etiologic fraction for high-risk human papillomavirus in oral cavity squamous cell carcinomas.
Low frequency of positive telomerase activity in a chromophobe subtype of renal cell carcinoma.
Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs).
Low Level of TERC Gene Amplification between Chronic Myeloid Leukaemia Patients Resistant and Respond to Imatinib Mesylate Treatment.
Low telomerase activity: possible role in the progression of human medullary thyroid carcinoma.
Low thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase mRNA expression correlate with prolonged survival in resected non-small-cell lung cancer.
Low-dose cisplatin converts the tumor microenvironment into a permissive state for HSVtk-induced antitumor immunity in HPV16-related tonsillar carcinoma.
Low-dose etoposide enhances telomerase-dependent adenovirus-mediated cytosine deaminase gene therapy through augmentation of adenoviral infection and transgene expression in a syngeneic bladder tumor model.
LPTS: A Novel Tumor Suppressor Gene and a Promising Drug Target for Cancer Intervention.
Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression.
Lymph node metastases, not human telomerase reverse transcriptase or p53 proteins, as the strongest prognostic factor for survival in early stage cervical cancer.
Lysine-Specific Demethylase 1 (LSD1) Is Required for the Transcriptional Repression of the Telomerase Reverse Transcriptase (hTERT) Gene.
Lysophosphatidic acid activates telomerase in ovarian cancer cells through hypoxia-inducible factor-1alpha and the PI3K pathway.
Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities.
Mad1 suppresses bladder cancer cell proliferation by inhibiting human telomerase reverse transcriptase transcription and telomerase activity.
Magnetic bead and nanoparticle based electrochemiluminescence amplification assay for direct and sensitive measuring of telomerase activity.
Magnetic bead-enzyme assemble for triple-parameter telomerase detection at single-cell level.
Magnetic resonance tumor targeting imaging using gadolinium labeled human telomerase reverse transcriptase antisense probes.
Magneto-mechanical detection of nucleic acids and telomerase activity in cancer cells.
Malignant transformation in human chondrosarcoma cells supported by telomerase activation and tumor suppressor inactivation.
Malignant transformation potentials of human umbilical cord mesenchymal stem cells both spontaneously and via 3-methycholanthrene induction.
Mammalian telomerase: catalytic subunit and knockout mice.
Mammalian telomere dynamics: healing, fragmentation shortening and stabilization.
Mammalian telomeres and telomerase.
Mammalian telomeres and telomerase: why they matter for cancer and aging.
Mammary carcinoma behavior is programmed in the precancer stem cell.
Mammary epithelial cell transformation: insights from cell culture and mouse models.
Mammary tumor virus induction by glucocorticoids. Characterization of specific transcriptional regulation.
Management of intraductal papillary-mucinous neoplasm of the pancreas: treatment strategy based on morphologic classification.
Mangiferin and Cancer: Mechanisms of Action.
Mannan-modified adenovirus as a vaccine to induce antitumor immunity.
Many disease-associated variants of hTERT retain high telomerase enzymatic activity.
Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization.
Mapping the FEN1 interaction domain with hTERT.
Marked difference in tumor necrosis factor-alpha expression in warm ischemia- and cold ischemia-reperfusion of the rat liver.
Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms.
Mathematical model of alternative mechanism of telomere length maintenance.
MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity.
MCP-3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells.
MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic lymphocytic leukemia.
MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene.
MDR1/P-glycoprotein and MRP-1 mRNA and protein expression in non-small cell lung cancer.
MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells.
Means to the ends: The role of telomeres and telomere processing machinery in metastasis.
Measurement of telomerase activity in bovine leukaemia virus infected cows.
Measurement of telomerase activity in dog tumors.
Measuring telomerase activity for the early detection of cancer.
Measuring Telomerase Activity in Senescent Human T Cells Upon Genetic Modification.
Measuring telomerase activity in various human tumors in routine histology and cytology.
Mechanism for the reduction of telomerase expression during muscle cell differentiation.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.
Mechanism of Human Telomerase Reverse Transcriptase (hTERT) Regulation and Clinical Impacts in Leukemia.
Mechanism-based combination telomerase inhibition therapy.
Mechanisms for inhibition of colon cancer cells by sulforaphane through epigenetic modulation of microRNA-21 and human telomerase reverse transcriptase (hTERT) down-regulation.
Mechanisms for telomerase gene control in aging cells and tumorigenesis.
Mechanisms of cell immortalization mediated by EB viral activation of telomerase in nasopharyngeal carcinoma.
Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer.
Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs.
Mechanisms of telomere loss and their consequences for chromosome instability.
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players.
Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters.
Mechanistic considerations in the evaluation of chemopreventive data.
Mechanixm of Carcinogenesis By RNA Tumor Viruses, I. An RNA-Dependent DNA Polymerase In Murine Sarcoma Viruses.
Meditation and vacation effects have an impact on disease-associated molecular phenotypes.
Meeting report: the role of telomeres and telomerase in cancer.
Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF.
Melatonin down-regulates hTERT expression induced by either natural estrogens (17beta-estradiol) or metalloestrogens (cadmium) in MCF-7 human breast cancer cells.
Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro.
Melatonin, an inhibitory agent in breast cancer.
MEN1 tumor-suppressor protein localizes to telomeres during meiosis.
Meningioma: an update.
Meningiomas, dicentric chromosomes, gliomas, and telomerase activity.
Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers.
Mesenchymal stem cells as therapeutic delivery vehicles targeting tumor stroma.
Meta-analysis for diagnostic accuracy studies: a new statistical model using beta-binomial distributions and bivariate copulas.
Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
Metallothionein: an overview.
Metastases suppressor NME2 associates with telomere ends and telomerase and reduces telomerase activity within cells.
Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in Klatskin tumor patients.
Metastatic retroperitoneal paraganglioma in a 16-year-old girl. Case report, molecular pathological and cytogenetic findings.
Methods for investigating G-quadruplex DNA/ligand interactions.
Methods for the molecular analysis of cancer. An overview.
Methods of telomerase inhibition.
Methylation of the hTERT promoter: a novel cancer biomarker for leptomeningeal metastasis detection in cerebrospinal fluids.
Methylation of the human telomerase gene CpG island.
Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer.
Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.
Methylation-related silencing of p14ARF gene correlates with telomerase activity and mRNA expression of human telomerase reverse transcriptase in hepatocellular carcinoma.
Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.
Microanalytical system for determination of picogram quantities of metals in metalloenzymes, as illustrated with zinc-containing enzymes.
Microarray analyses in bladder cancer cells: inhibition of hTERT expression down-regulates EGFR.
Microarray TRAP--a high-throughput assay to quantitate telomerase activity.
Microcell-mediated transfer of chromosome 4 into HeLa cells suppresses telomerase activity.
MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.
MicroRNA Regulation of Telomerase Reverse Transcriptase (TERT): Micro Machines Pull Strings of Papier-Mâché Puppets.
MicroRNA-1 and MicroRNA-21 Individually Regulate Cellular Growth of Non-malignant and Malignant Renal Cells.
MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3' untranslated region.
MicroRNA-dependent Regulation of Telomere Maintenance Mechanisms: a Field as Much Unexplored as Potentially Promising.
Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients.
Mini- and microsatellites.
Minimal residual disease in thyroid carcinoma.
Minimizing the risk of cancer: tissue architecture and cellular replication limits.
miR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame of hTERT.
miR-128 inhibits telomerase activity by targeting TERT mRNA.
miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo.
miR-138-5p acts as a tumor suppressor by targeting hTERT in human colorectal cancer.
miR-195-5p regulates cell proliferation, apoptosis, and invasion of thyroid cancer by targeting telomerase reverse transcriptase.
miR-19b regulates hTERT mRNA expression through targeting PITX1 mRNA in melanoma cells.
miR-221/222: promising biomarkers for breast cancer.
miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway.
miR-380-5p-mediated repression of TEP1 and TSPYL5 interferes with telomerase activity and favours the emergence of an "ALT-like" phenotype in diffuse malignant peritoneal mesothelioma cells.
miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.
miRNA mediated up-regulation of cochaperone p23 acts as an anti-apoptotic factor in childhood acute lymphoblastic leukemia.
Missing association between telomerase activity and clinicopathological features in patients with early stage carcinoma of the cervix.
Mistletoe lectin induces apoptosis and telomerase inhibition in human A253 cancer cells through dephosphorylation of Akt.
Mistletoe lectins: telomerase inhibitors in alternative cancer therapy.
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.
Mitotic instability in cancer: is there method in the madness?
Mitotoxicity in distal symmetrical sensory peripheral neuropathies.
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression.
MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome.
MNS16A Tandem Repeats Minisatellite of Human Telomerase Gene and Cancer Risk: A Meta-Analysis.
MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer.
Modeling aging and cancer in the telomerase knockout mouse.
Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse.
Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma.
Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach.
Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.
Moderate stem-cell telomere shortening rate postpones cancer onset in a stochastic model.
Modification of the hTERT promoter by heat shock elements enhances the efficiency and specificity of cancer targeted gene therapy.
Modulating telomerase activity in tumor patients by targeting dyskerin binding site for hTR.
Modulation of cytokines and transcription factors (T-Bet and GATA3) in CD4 enriched cervical cells of Chlamydia trachomatis infected fertile and infertile women upon stimulation with chlamydial inclusion membrane proteins B and C.
Modulation of human epidermal cell response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by epidermal growth factor.
Modulation of human telomerase reverse transcriptase in hepatocellular carcinoma.
Modulation of telomerase activity by zinc in human prostatic and renal cancer cells.
Modulation of Telomerase Activity in Cancer Cells by Dietary Compounds: A Review.
Modulation of telomerase activity in fish muscle by biological and environmental factors.
Modulation of telomerase and signal transduction proteins by Hexyl-ALA-Photodynamic Therapy (PDT) in human doxorubicin resistant cancer cell models.
Modulation of telomerase expression and function by miRNAs: Anti-cancer potential.
Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses.
Modulation of telomere shelterin by TRF1 [corrected] and TRF2 interacts with telomerase to maintain the telomere length in non-small cell lung cancer.
Molecular alterations in endometrial and ovarian clear cell carcinomas: clinical impacts of telomerase reverse transcriptase promoter mutation.
Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections.
Molecular and Cellular Evidence for the Alternative Lengthening of Telomeres (ALT) Mechanism in Chicken.
Molecular aspects of invasion and metastasis of stomach cancer.
Molecular basis for the cellular senescence program and its application to anticancer therapy.
Molecular basis of artifacts in the detection of telomerase activity and a modified primer for a more robust 'TRAP' assay.
Molecular basis of chemosensitivity of platinum pre-treated ovarian cancer to chemotherapy.
Molecular biology of colorectal cancer.
Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine.
Molecular characterization of a series of solitary fibrous tumors, including immunohistochemical expression of STAT6 and NATB2-STAT6 fusion transcripts, using Reverse Transcriptase(RT)-Polymerase chain reaction(PCR) technique: An Indian experience.
Molecular characterization of head and neck tumors by analysis of telomerase activity and a panel of microsatellite markers.
Molecular classification of follicular thyroid carcinoma based on TERT promoter mutations.
Molecular classification of gliomas.
Molecular cloning of the canine telomerase reverse transcriptase gene and its expression in neoplastic and non-neoplastic cells.
Molecular cloning of the feline telomerase reverse transcriptase (TERT) gene and its expression in cell lines and normal tissues.
Molecular design of synthetic benzimidazoles for the switchover of the duplex to G-quadruplex DNA recognition.
Molecular detection and characterization of circulating tumor cells and micrometastases in prostatic, urothelial, and renal cell carcinomas.
Molecular Detection of Circulating Tumor Cells in the Peripheral Blood of Patients with Colorectal Cancer Using RT-PCR: Significance of the Prediction of Postoperative Metastasis.
Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance of the prediction of postoperative metastasis.
Molecular detection of disseminated tumor cells in the peripheral blood of patients with gastric cancer: evaluation of their prognostic significance.
Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse.
Molecular detection of telomerase-positive circulating epithelial cells in metastatic breast cancer patients.
Molecular diagnosis of gastric cancer: present and future.
Molecular diagnosis of solid and cystic lesions of the pancreas.
Molecular diagnostics of gliomas using next generation sequencing of a glioma-tailored gene panel.
Molecular docking based screening of triterpenoids as potential G-quadruplex stabilizing ligands with anti-cancer activity.
Molecular dynamics and principal components of potassium binding with human telomeric intra-molecular G-quadruplex.
Molecular genetic evaluation of fluorescence diagnosis in bladder cancer.
Molecular genetics of bladder cancer: targets for diagnosis and therapy.
Molecular identification of telomerase reverse transcriptase (TERT) promotor mutations in primary and recurrent tumors of invasive and noninvasive urothelial bladder cancer.
Molecular imaging of telomerase and the enzyme activity-triggered drug release by using a conformation-switchable nanoprobe in cancerous cells.
Molecular insight into the selective binding between human telomere G-quadruplex and a negatively charged stabilizer.
Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro.
Molecular markers and bladder carcinoma: Schistosomal and non-schistosomal.
Molecular markers implicating early malignant events in cervical carcinogenesis.
Molecular markers in lung cancer: prognostic role and relationship to smoking.
Molecular markers of pancreatic cancer: development and clinical relevance.
Molecular markers of prognosis and therapeutic targets in metastatic colorectal cancer.
Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells.
Molecular mechanism of hepatocarcinogenesis.
Molecular mechanism of human stomach carcinogenesis implicated in Helicobacter pylori infection.
Molecular Mechanism of Telomere Length Dynamics and Its Prognostic Value in Pediatric Cancers.
Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast.
Molecular Modeling and Evaluation of Novel Dibenzopyrrole Derivatives as Telomerase Inhibitors and Potential Drug for Cancer Therapy.
Molecular pathogenesis of aging and cancer: are telomeres and telomerase the connection?
Molecular pathogenesis of pediatric thyroid carcinoma.
Molecular prognostic markers in resectable colorectal liver metastases: a systematic review.
Molecular recognition of 3+1 hybrid human telomeric G-quadruplex DNA d-[AGGG(TTAGGG)3] by anticancer drugs epirubicin and adriamycin leads to thermal stabilization.
Molecular regulation of telomerase activity in aging.
Molecular staging of lung cancer: real-time polymerase chain reaction estimation of lymph node micrometastatic tumor cell burden in stage I non-small cell lung cancer--preliminary results of Cancer and Leukemia Group B Trial 9761.
Molecular staging of pelvic surgical margins after radical prostatectomy: comparison of RT-PCR for prostate-specific antigen and telomerase activity.
Molecular targeting of neural cancer stem cells: TTAGGG, you're it!
Molecular targets in cancer prevention by 4-(methylthio)butyl isothiocyanate - A comprehensive review.
Molecular-pathological diagnosis of gastrointestinal tissues and its contribution to cancer histopathology.
Molecularly imprinted gelatin nanoparticles for DNA delivery and in-situ fluorescence imaging of telomerase activity.
Monitoring Telomerase Activity in Living Cells with High Sensitivity Using Cascade Amplification Reaction-Based Nanoprobe.
Monoclonal antibodies against human telomerase reverse transcriptase (hTERT): preparation, characterization, and application.
Monocytes from mobilized stem cells inhibit T cell function.
Monokine-mediated increase in human immunodeficiency virus type 1 expression in chronically infected promonocyte- and T-cell-derived lines.
Motilin receptor expression in smooth muscle, myenteric plexus, and mucosa of human inflamed and noninflamed intestine.
Mouse mammary tumour virus RNA-dependent DNA polymerase: requirements and products.
Mouse models for the study of telomerase.
Mouse models to study the role of telomeres in cancer, aging and DNA repair.
MOV10 as a novel telomerase-associated protein.
MR molecular imaging of tumours using ferritin heavy chain reporter gene expression mediated by the hTERT promoter.
MRI-Based Radiomics and Radiogenomics in the Management of Low-Grade Gliomas: Evaluating the Evidence for a Paradigm Shift.
mRNA quantification and clinical evaluation of telomerase reverse transcriptase subunit (hTERT) in intracranial tumours of patients in the island of Crete.
MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells.
MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-?B pathway.
Multi-code magnetic beads based on DNAzyme-mediated double-cycling amplification for a point-of-care assay of telomerase activity.
Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks.
Multicenter phase I study of repeated intratumoral delivery of adenoviral p53 in patients with advanced non-small-cell lung cancer.
Multicenter Phase II trial of S-1 in Patients With Cytokine-Refractory Metastatic Renal Cell Carcinoma.
Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures.
Multicolor Fluorescent Graphene Oxide Quantum Dots for Sensing Cancer Cell Biomarkers.
Multidisciplinary oncolytic virotherapy for gastrointestinal cancer.
Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma.
Multimodal genetic diagnosis of solid variant alveolar rhabdomyosarcoma.
Multiple cancer pathways regulate telomere protection.
Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines in in vitro culture.
Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray.
Multiple hepatic arterial injections of recombinant adenovirus p53 and 5-fluorouracil after transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma: a pilot phase II trial.
Multiple Mechanisms Contribute To Telomere Maintenance.
Multiple mechanisms of telomere maintenance exist in liposarcomas.
Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.
Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.
Multiple pathways for the regulation of telomerase activity.
Multiple pathways to cellular senescence: role of telomerase repressors.
Multiple tumor suppressor microRNAs regulate telomerase and TCF7, an important transcriptional regulator of the Wnt pathway.
Multiple tumor suppressor pathways negatively regulate telomerase.
Multiplexed electrical detection of cancer markers with nanowire sensor arrays.
Multivalent Self-Assembled DNA Polymer for Tumor-Targeted Delivery and Live Cell Imaging of Telomerase Activity.
Mutant telomerase RNAs induce DNA damage and apoptosis via TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts.
Mutated telomeres sensitize tumor cells to anticancer drugs independently of telomere shortening and mechanisms of telomere maintenance.
Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carcinoma.
Mutation of the TERT promoter leads to poor prognosis of patients with non-small cell lung cancer.
Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
Mutational analysis defines a minimum level of telomerase activity required for tumourigenic growth of human cells.
Mutational analysis of PINX1 in hereditary prostate cancer.
Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma.
Myc activates telomerase.
MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.
Myc, Cdk2 and cellular senescence: Old players, new game.
Myeloid dendritic cells loaded with dendritic tandem multiple antigenic telomerase reverse transcriptase (hTERT) epitope peptides: a potentially promising tumor vaccine.
Myelosuppression in Patients Treated with the Telomerase Inhibitor Imetelstat Is Not Mediated through Activation of Toll-Like Receptors.
Myxoid liposarcoma with transition to round-cell lesion-cell cycle regulator genes and telomerase activity characterizing tumor progression: a case report.
N-(1-Pyrenyl) maleimide inhibits telomerase activity in a cell free system and induces apoptosis in Jurkat cells.
N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells.
N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.
NAC selectively inhibit cancer telomerase activity: A higher redox homeostasis threshold exists in cancer cells.
Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells.
Naphthalenediimide-Linked Bisbenzimidazole Derivatives as Telomeric G-Quadruplex-Stabilizing Ligands with Improved Anticancer Activity.
Natural and pharmacological regulation of telomerase.
Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents.
Neoplastic conversion of human colon smooth muscle cells: No requirement for telomerase.
Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells.
Neosis--a paradigm of self-renewal in cancer.
Neural stem cells lose telomerase activity upon differentiating into astrocytes.
Neural Stem Cells of the Subventricular Zone as the Origin of Human Glioblastoma Stem Cells. Therapeutic Implications.
Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition.
Neurotensin receptor-3/sortilin mediates neurotensin-induced cytokine/chemokine expression in a murine microglial cell line.
New attempt of preoperative differential diagnosis of thyroid neoplasms by telomerase activity measurement.
New diagnostic strategies in the detection and staging of bladder cancer.
New Functions for Telomerase.
New horizons for diagnostics and therapeutic applications of graphene and graphene oxide.
New method to measure telomerase activity by transcription-mediated amplification and hybridization protection assay.
New molecular markers for bladder cancer detection.
New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication.
New perspectives for tumor pathology provided by comparative genomic hybridization.
New prospects for targeting telomerase beyond the telomere.
New surprises from an old favourite: The emergence of telomerase as a key player in the regulation of cancer stemness.
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163.
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin.
Next-generation sequencing of urine specimens: A novel platform for genomic analysis in patients with non-muscle-invasive urothelial carcinoma treated with bacille Calmette-Guérin.
NF-?B potentiates tumor growth by suppressing a novel target LPTS.
NFX1-123 is highly expressed in cervical cancer and increases growth and telomerase activity in HPV 16E6 expressing cells.
NHP2 downregulation counteracts hTR-mediated activation of the DNA damage response at ALT telomeres.
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma.
Nitric oxide modulates pro- and anti-inflammatory cytokines in lipopolysaccharide-activated macrophages.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
NMR based structural studies decipher stacking of the alkaloid coralyne to terminal guanines at two different sites in parallel G-quadruplex DNA, [d(TTGGGGT)]
No evidence for particles encapsulating RNA-instructed DNA polymerase and high molecular weight virus-related RNA in herpesvirus induced tumours of non-human primates.
Non-canonical Functions of Telomerase Reverse Transcriptase: Emerging Roles and Biological Relevance.
Non-canonical NF-?B signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.
Non-canonical roles of canonical telomere binding proteins in cancers.
Non-homologous end-joining protein expression screen from radiosensitive cancer patients yields a novel DNA double strand break repair phenotype.
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Non-radioactive assay methods for the assessment of telomerase activity and telomere length.
Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine.
Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.
Nonalcoholic Steatohepatitis: Involvement of the Telomerase and Proinflammatory Mediators.
Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Nonhuman primate parthenogenetic stem cells.
Noninvasive and real-time monitoring of the therapeutic response of tumors in vivo with an optimized hTERT promoter.
Noninvasive detection of prostate cancer by quantitative analysis of telomerase activity.
Noninvasive imaging of human telomerase reverse transcriptase (hTERT) messenger RNA with 99mTc-radiolabeled antisense probes in malignant tumors.
Noninvasive visualization of RNA delivery with 99mTc-radiolabeled small-interference RNA in tumor xenografts.
Nonradioactive and Radioactive Telomerase Assays for Detecting Diminished Telomerase Activity in Cancer Cells after Treatment with Retinoid.
Nonradioactive direct telomerase activity detection using biotin-labeled primers.
Nonradioactive telomerase activity assay by microchip electrophoresis: privileges to the classical gel electrophoresis assay.
Nonradioisotopic telomeric repeat amplification protocol (TRAP) using digoxigenin labeled probe.
Normal and Tumour Tissue mRNA Expressions of Telomerase Complex Genes in Several Types of Cancer.
Normal human immune cells are sensitive to telomerase inhibition by Brassica-derived 3,3-diindolylmethane,partly mediated via ER?/?-AP1 signaling.
Normal mammalian cells negatively regulate telomere length by telomere trimming.
NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells.
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer.
Novel anticancer therapeutics targeting telomerase.
Novel combination of tanshinone I and lenalidomide induces chemo-sensitivity in myeloma cells by modulating telomerase activity and expression of shelterin complex and its associated molecules.
Novel dihydropyrazole-chromen: Design and modulates hTERT inhibition proliferation of MGC-803.
Novel Efficient Cell-Penetrating, Peptide-Mediated Strategy for Enhancing Telomerase Inhibitor Oligonucleotides.
Novel Human Prostate Epithelial Cell Cultures.
Novel myricetin derivatives: Design, synthesis and anticancer activity.
Novel nanosensors for rapid analysis of telomerase activity.
Novel Oligopyrrole Carboxamide based Nickel(II) and Palladium(II) Salens, Their Targeting of Human G-Quadruplex DNA, and Selective Cancer Cell Toxicity.
Novel plasma telomerase detection method to improve cancer diagnostic assessment.
Novel platinum complexes as efficient G-quadruplex DNA binders and telomerase inhibitors.
Novel roles for telomerase in aging.
Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton's lymphoma ascites tumor.
Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis.
Novel telomeric repeat elongation assay performed on zinc oxide nanorod array supports.
Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma.
Novel Therapies in Myeloproliferative Neoplasms (MPN): Beyond JAK Inhibitors.
Novel, chimeric, cancer-specific, and radiation-inducible gene promoters for suicide gene therapy of cancer.
Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma.
NSC746364, NSC746365, and NSC746366: the spectra of cytotoxicity and molecular correlates of response to telomerase activity.
Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein.
Nuclear hTERT immunohistochemical expression is associated with survival of patients with urothelial bladder cancer.
Nuclear import of hTERT requires a bipartite nuclear localization signal mediated by Akt phosphorylation.
Nuclear telomerase is less accessible to antibody probing than known nuclear antigens: retrieval with new immunostaining buffer.
Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis.
Nuclear-Shell Biopolymers Initiated by Telomere Elongation for Individual Cancer Cell Imaging and Drug Delivery.
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
Nucleic acids as targets for antitelomerase agents.
Nucleolin-Targeted DNA Nanotube for Precise Cancer Therapy through Förster Resonance Energy Transfer-Indicated Telomerase Responsiveness.
Observation of processive telomerase catalysis using high-resolution optical tweezers.
Occurrence, functionality and abundance of the TERT promoter mutations.
Oesophageal basaloid squamous cell carcinoma: a unique clinicopathological entity with telomerase activity as a prognostic indicator.
Of telomeres and tumors.
Oligodendroglioma showing pleomorphic xanthoastrocytoma-like perivascular microlesion: With IDH1, TERT promoter mutation and 1p/19q codeletion detected in both components.
Oligonucleotide conjugate GRN163L targeting human telomerase as potential anticancer and antimetastatic agent.
Oligonucleotide inhibitors of telomerase: prospects for anticancer therapy and diagnostics.
Oligonucleotide N3' --> P5' thio-phosphoramidate telomerase template antagonists as potential anticancer agents.
Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.
Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides.
Oligonucleotides and G-quadruplex Stabilizers: Targeting Telomeres and Telomerase in Cancer Therapy.
Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer Therapy.
Oligonucleotides Targeting Telomeres and Telomerase in Cancer.
Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults.
On telomere shortening in soft-tissue tumors.
On the comparative biology of mammalian telomeres: Telomere length co-evolves with body mass, lifespan and cancer risk.
On the road to immortality: hTERT upregulation in cancer cells.
On the significance of telomerase activity in human malignant glioma cells.
On the stimulation of viral DNA polymerase activity by nonionic detergent.
Oncoapoptotic signaling and deregulated target genes in cancers: special reference to oral cancer.
Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres.
Oncogenic transformation and experimental models of human cancer.
Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice.
Oncolytic adenovirus that overproduces ADP and replicates selectively in tumors due to hTERT promoter-regulated E4 gene expression.
Oncolytic adenovirus-induced autophagy: tumor-suppressive effect and molecular basis.
Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer.
Oncornavirus-like particles in human skin cancers.
One-step affinity purification protocol for human telomerase.
One-Step High-Throughput Telomerase Activity Measurement of Cell Populations, Single Cells, and Single-Enzyme Complexes.
One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation.
Onset of Telomere Dysfunction and Fusions in Human Ovarian Carcinoma.
Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling.
Opposing regulatory roles of E2F in human telomerase reverse transcriptase (hTERT) gene expression in human tumor and normal somatic cells.
Optimization of a gene electrotransfer procedure for efficient intradermal immunization with an hTERT-based DNA vaccine in mice.
Optimized tumor cryptic peptides: the basis for universal neo-antigen-like tumor vaccines.
Oral cancer diagnosis via a ferrocenylnaphthalene diimide-based electrochemical telomerase assay.
ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization.
Organ- and tissue-specific stem cells and carcinogenesis.
Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans.
Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.
ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide.
Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases.
Ovarian Telomerase and Female Fertility.
Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics--current status and future prospects.
Overexpression of Beclin1 gene leads to reduction of telomerase activity in MDCK cells and enhances apoptosis.
Overexpression of cellular telomerase RNA enhances virus-induced cancer formation.
Overexpression of glucose-regulated protein 78 in colon cancer.
Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro.
Overexpression of human telomerase RNA in Helicobacter pylori-infected human gastric mucosa.
Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis.
Overexpression of MMP-13 gene in colorectal cancer with liver metastasis.
Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas.
Overexpression of the p21 sdi1 gene induces senescence-like state in human cancer cells: implication for senescence-directed molecular therapy for cancer.
Overexpression of tissue inhibitor of metalloproteinase-1 gene correlates with poor outcomes in colorectal cancer.
Overview on pathophysiology and newer approaches to treatment of peripheral neuropathies.
Overview: translating Hsp90 biology into Hsp90 drugs.
Oxidative Damage Impact on Aging and Age-Related Diseases: Drug Targeting of Telomere Attrition and Dynamic Telomerase Activity Flirting with Imidazole-Containing Dipeptides.
Oxidative DNA Damage in Barrett Mucosa: Correlation with Telomeric Dysfunction and p53 Mutation.
Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer.
Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase activation.
Oxidative stress pathways highlighted in tumor cell immortalization: association with breast cancer outcome.
Oxidative Stress: Role and Response of Short Guanine Tracts at Genomic Locations.
Oxoisoaporphines and Aporphines: Versatile Molecules with Anticancer Effects.
Oxymatrine improves intestinal epithelial barrier function involving NF-?B-mediated signaling pathway in CCl4-induced cirrhotic rats.
P-glycoprotein is expressed and causes resistance to chemotherapy in EBV-positive T-cell lymphoproliferative diseases.
p16(INK4a) and the control of cellular proliferative life span.
p21(WAF1) is involved in interferon-?- induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression in ovarian cancer.
P53 expression, p53 and Ha-ras mutation and telomerase activation during nitrosamine-mediated hamster pouch carcinogenesis.
p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma.
p53-dependent down-regulation of telomerase is mediated by p21waf1.
P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment.
PAMAM dendrimers augment inhibitory effects of curcumin on cancer cell proliferation: possible inhibition of telomerase.
Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes.
Pan-Cancer Analysis of Alternative Lengthening of Telomere Activity.
Pancreatic Tumor Progression Associated With CD133 Overexpression: Involvement of Increased TERT Expression and Epidermal Growth Factor Receptor-Dependent Akt Activation.
PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells.
Parrot Genomes and the Evolution of Heightened Longevity and Cognition.
Part I. Telomerase levels in human metastatic brain tumors show four-fold logarithmic variability but no correlation with tumor type or interval to patient demise.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Partial p16 staining in oropharyngeal squamous cell carcinoma: extent and pattern correlate with human papillomavirus RNA status.
Particles containing RNA-instructed DNA polymerase and virus-related RNA in human breast cancers.
Paternal high-fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring.
Pathogenesis of hepatocellular carcinoma.
Pathology and genomics of pediatric melanoma: A critical reexamination and new insights.
Pathophysiology of ocular surface squamous neoplasia.
PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity.
PCR-free and label-free fluorescent detection of telomerase activity at single-cell level based on triple amplification.
Peculiarities of Yeasts and Human Telomerase RNAs Processing.
Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase.
Performance characteristics of multiple urinary tumor markers and sample collection techniques in the detection of transitional cell carcinoma of the bladder.
Perifosine as a potential novel anti-telomerase therapy.
Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease.
Pervasive promoter hypermethylation of silenced TERT alleles in human cancers.
PES1 is a critical component of telomerase assembly and regulates cellular senescence.
Pharmaceutical regulation of telomerase and its clinical potential.
Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin.
Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents.
Pharmacological activities and mechanisms of natural phenylpropanoid glycosides.
Pharmacological intervention strategies for affecting telomerase activity: future prospects to treat cancer and degenerative disease.
Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment.
Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors.
Phenolic compounds, saponins and alkaloids on cancer progression: emphasis on p53 expression and telomere length.
Phosphorothioate?modified antisense oligonucleotides against human telomerase reverse transcriptase sensitize cancer cells to radiotherapy.
Phosphorylation status of Fas-associated death domain-containing protein regulates telomerase activity and strongly correlates with prostate cancer outcomes.
Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity.
Physiological and pathological significance of human telomerase reverse transcriptase splice variants.
Physiological relevance of telomeric G-quadruplex formation: a potential drug target.
Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3.
Pif1 helicase and Pol? promote recombination-coupled DNA synthesis via bubble migration.
Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.
Pigmented epithelioid melanocytoma (animal-type melanoma): An institutional experience.
Pilocytic Astrocytomas Have Telomere-Associated Promyelocytic Leukemia Bodies without Alternatively Lengthened Telomeres.
Pin2 telomeric repeat factor 1-interacting telomerase inhibitor 1 (PinX1) inhibits nasopharyngeal cancer cell stemness: implication for cancer progression and therapeutic targeting.
Pin2/TRF1?binding protein X1 inhibits colorectal cancer cell migration and invasion in vitro and metastasis in vivo via the nuclear factor??B signaling pathway.
Pineal parenchymal tumor of intermediate differentiation: clinicopathological report and analysis of epidermal growth factor receptor variant III expression.
PinX1 gene transfection enhances the sensitivity of gastric carcinoma cell line to 5-fluorouracil.
PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-?B/MMP-9 signaling pathway.
PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway.
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway.
PinX1 the tail on the chromosome.
PinX1 without the G-patch motif suppresses proliferation, induces senescence, but does not inhibit telomerase activity in colorectal cancer SW480 cells.
PinX1: a sought-after major tumor suppressor at human chromosome 8p23.
Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo.
Pitfalls in TRAP assay in routine detection of malignancy in effusions.
PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription.
Plant alkaloid chelerythrine induced aggregation of human telomere sequence--a unique mode of association between a small molecule and a quadruplex.
Plasma Leptin, hTERT Gene Expression, and Anthropometric Measures in Obese and Non-Obese Women with Breast Cancer.
Platinum phenanthroimidazole complexes as G-quadruplex DNA selective binders.
Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization.
Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells.
Plumbagin triggers DNA damage response, telomere dysfunction and genome instability of human breast cancer cells.
PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening.
PML is required for telomere stability in non-neoplastic human cells.
Point-of-Care Assay of Telomerase Activity at Single-Cell Level via Gas Pressure Readout.
Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.
Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity.
Poly(U) binding splicing factor 60 promotes renal cell carcinoma growth by transcriptionally upregulating telomerase reverse transcriptase.
Polyamidoamine starburst dendrimer-activated chromatography paper-based assay for sensitive detection of telomerase activity.
Polyelectrolyte complexes of hTERT siRNA and polyethyleneimine: Effect of degree of PEG grafting on biological and cellular activity.
Polymorphism of human telomeric quadruplex structures.
Polymorphisms of TERT and CLPTM1L and the risk of hepatocellular carcinoma in Chinese males.
Polymorphisms of the TERT-CLPTM1L Gene Are Associated with Pharynx-Larynx Cancer.
Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility.
Polyunsaturated fatty acids inhibit telomerase activity in DLD-1 human colorectal adenocarcinoma cells: a dual mechanism approach.
Porphyrin derivatives for telomere binding and telomerase inhibition.
Positive association of long telomeres with the invasive capacity of hepatocellular carcinoma cells.
Possible immortalization of Hodgkin and Reed-Sternberg cells: telomerase expression, lengthening of telomere, and inhibition of apoptosis by NF-kappaB expression.
Possible mechanisms for the regulation of telomere length.
Possible role of telomerase activation in the cancer predisposition of patients with hereditary nonpolyposis colorectal cancers.
Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposis.
Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal disease.
Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma.
Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays.
Potent inhibition of human telomerase by helenalin.
Potent inhibition of human telomerase by nitrostyrene derivatives.
Potent inhibition of human telomerase by U-73122.
Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes.
Potent inhibitory activity of chimeric oligonucleotides targeting two different sites of human telomerase.
Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone.
Potential clinical role of telomere length in human glioblastoma.
Potential clinical significance of perioperative levels of mRNA in plasma from patients with cancer of the larynx or hypopharynx.
Potential involvement of tumor suppressor gene expression in the formation of estrogen-inducible pituitary tumors in rats.
Potential mouse tumor model for pre-clinical testing of mage-specific breast cancer vaccines.
Potential of Naturally Derived Compounds in Telomerase and Telomere Modulation in Skin Senescence and Aging.
Potential Telomere-Related Pharmacological Targets.
PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase.
Precancerous hepatic nodules had significant levels of telomerase activity determined by sensitive quantitation using a hybridization protection assay.
Preclinical evaluation of differentially targeting dual virotherapy for human solid cancer.
Preclinical pharmacology and toxicology study of Ad-hTERT-E1a-Apoptin, a novel dual cancer-specific oncolytic adenovirus.
Preclinical studies on detection of circulating melanoma cells in patients: telomerase as a recognition marker of malignancy.
Predicting clinical outcome in feline oral squamous cell carcinoma: tumour initiating cells, telomeres and telomerase.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity level.
Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation.
Prediction of telomerase inhibitory activity for acridinic derivatives based on chemical structure.
Predictive and prognostic significance of telomerase levels/telomere length in tissues and peripheral blood in head and neck squamous cell carcinoma.
Predictive role of telomerase activity in the clinical outcome of patients with benign lesions of the uterine cervix or CIN.
Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis.
Preferential binding of a G-quadruplex ligand to human chromosome ends.
Preferential extension of short telomeres induced by low extracellular pH.
Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.
Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells.
Preliminary development of an assay for detection of TERT expression, telomere length, and telomere elongation in single cells.
Preoperative Assessment of TERT Promoter Mutation on Thyroid Core Needle Biopsies Supports Diagnosis of Malignancy and Addresses Surgical Strategy.
Preoperative detection of the TERT promoter mutations in papillary thyroid carcinomas.
Preoperative diagnosis of intraductal papillary-mucinous tumors of the pancreas with attention to telomerase activity.
Preoperative peripheral blood human telomerase reverse transcriptase mRNA concentration is not a prognostic factor for resection of hepatocellular carcinoma.
Preparation and characterization of candidate reference materials for telomerase assays.
Preparation of monoclonal antibodies against human telomerase.
Presence of alternative lengthening of telomeres associated circular extrachromosome telomere repeats in primary leukemia cells of chronic myeloid leukemia.
Presence of bovine papillomavirus type 2 DNA and expression of the viral oncoprotein E5 in naturally occurring urinary bladder tumours in cows.
Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness.
Presence of telomerase activity with undetectable p16 gene mutation in Malaysian patients with brain tumor.
Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition.
Prevalence of telomerase activity in human cancer.
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
Preventive vaccination with telomerase controls tumor growth in genetically engineered and carcinogen-induced mouse models of cancer.
Primary Astrocytic Tumours and Paired Recurrences have Similar Biological Features in IDH1, TP53 and TERTp Mutation and MGMT, ATRX Loss.
Primate RNA tumor virus-like DNA synthesized endogenously by RNA-dependent DNA polymerase in virus-like particles from fresh human acute leukemic blood cells.
Primer-Modified G-Quadruplex-Au Nanoparticles for Colorimetric Assay of Human Telomerase Activity and Initial Screening of Telomerase Inhibitors.
Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions.
Production of spindle cell carcinoma by transduction of H-Ras 61L into immortalized human mammary epithelial cells.
Profile of POT1 as telomerase shelterin component discriminatesbetween cervical cancer and normal cervical cells.
Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion.
Prognostic and Clinicopathological Value of PINX1 in Various Human Tumors: A Meta-Analysis.
Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas.
Prognostic factors in stage I/II non-small cell lung cancer.
Prognostic impact of telomerase activity in non-small cell lung cancers.
Prognostic implication of telomerase activity in patients with brain tumors.
Prognostic potential of the telomerase subunit human telomerase reverse transcriptase in tumor tissue and nontumorous mucosa from patients with colorectal carcinoma.
Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis.
Prognostic Relevance of Tumor Purity and Interaction with MGMT Methylation in Glioblastoma.
Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis.
Prognostic significance of disseminated tumor cells as detected by quantitative real-time reverse-transcriptase polymerase chain reaction in patients with breast cancer.
Prognostic Significance of Quantitative Carcinoembryonic Antigen and Cytokeratin 20 mRNA Detection in Peritoneal Washes of Gastric Cancer Patients.
Prognostic significance of reactivation of telomerase in breast core biopsy specimens.
Prognostic Significance of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression in Ampullary Carcinoma.
Prognostic significance of telomerase activity and some tumor markers in non-small cell lung cancer.
Prognostic significance of telomerase activity in soft tissue sarcomas.
Prognostic significance of telomerase in brain tumors
Prognostic significance of telomerase-associated parameters in glioblastoma: effect of patient age.
Prognostic significance of telomeric repeat length alterations in pathological stage I-IIIA non-small cell lung cancer.
Prognostic Value of Histologic and Immunohistochemical Features in Feline Cutaneous Mast Cell Tumors.
Prognostic value of telomerase and DNA ploidy in laryngeal carcinoma.
Prognostic value of tyrosinase reverse-transcriptase polymerase chain reaction in metastatic melanoma.
Progress of experimental researches on Chinese herbal compounds for inducing tumor cell apoptosis.
Progression of astrocytomas and meningiomas: an evaluation in vitro.
Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors.
Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma.
Progressive loss of malignant behavior in telomerase-negative tumorigenic adrenocortical cells and restoration of tumorigenicity by human telomerase reverse transcriptase.
Proinflammatory cytokine TNF? promotes HPV-associated oral carcinogenesis by increasing cancer stemness.
Proliferation characteristics of canine transmissible venereal tumor.
Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis.
Promoter CpG methylation inhibits Krüppel-like factor 2 (KLF2)-Mediated repression of hTERT gene expression in human T-cells.
Promoter hypermethylation of TERT is associated with hepatocellular carcinoma in the Han Chinese population.
Promoter trapping method: transcription factor purification using human telomerase reverse transcriptase promoter.
Propagation of mouse mammary tumor cell lines and production of mouse mammary tumor virus in a serum-free medium.
Properties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy.
Prospective study of hTERC gene detection by fluorescence in situ hybridization (FISH) in cervical intraepithelial neoplasia 1 natural prognosis.
Prospects and challenges of building a cancer vaccine targeting telomerase.
Prospects for anti-neoplastic therapies based on telomere biology.
Prostate carcinoma and stem cells.
Prostate derived Ets transcription factor shows better tumor-association than other cancer-associated molecules.
Prostate tumor cells with cancer progenitor properties have high telomerase activity and are rapidly killed by telomerase interference.
Prostate tumor-initiating cells: A new target for telomerase inhibition therapy?
Prostate-specific antigen (protein and mRNA) analysis in the differential diagnosis and staging of prostate cancer.
Prostate-specific antigen gene expression and telomerase activity in breast cancer patients: possible relationship to steroid hormone receptors.
Prostatic androgen repressed message-1 (PARM-1) may play a role in prostatic cell immortalisation.
Protein composition of catalytically active human telomerase from immortal cells.
Protein kinase C modulates telomerase activity in human cervical cancer cells.
Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells.
Proteins with antifungal properties and other medicinal applications from plants and mushrooms.
Proteomic and microRNA data clarifying the effects of telomere shortening on cancer cells.
Proteomic identification of proteins differentially expressed following overexpression of hTERT (human telomerase reverse transcriptase) in cancer cells.
Proteomic profiling in distinct cellular compartments of tumor cells reveals p53-dependent upregulation of S100A6 upon induction of telomere dysfunction.
Proteomic profiling of tumor cells after induction of telomere dysfunction.
Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase ? in the Alternative Lengthening of Telomeres.
Proteomic studies coupled with RNAi methodologies can shed further light on the downstream effects of telomerase in glioma.
Proximity binding-triggered multipedal DNA walker for the electrochemiluminescence detection of telomerase activity.
PTEN and hTERT gene expression and the correlation with human hepatocellular carcinoma.
Pterostilbene as a Potential Novel Telomerase Inhibitor: Molecular Docking Studies and its In Vitro Evaluation.
Pterostilbene down-regulates hTERT at physiological concentrations in breast cancer cells: Potentially through the inhibition of cMyc.
PTOP interacts with POT1 and regulates its localization to telomeres.
Purification and biochemical characterization of a virus-specific reverse transcriptase from human osteosarcoma tissue.
Purification and Characterization of a Laccase with Inhibitory Activity toward HIV-1 Reverse Transcriptase and Tumor Cells from an Edible Mushroom (Pleurotus cornucopiae).
Purification and characterization of a lectin from the Indian cultivar of French bean seeds.
Purification and characterization of a novel lectin with antiphytovirus activities from the wild mushroom Paxillus involutus.
Purification and properties of RNA-dependent DNA polymerase from cytoplasmic A-type particles of murine mammary tumor virus.
Purification of diseased cells from Barrett's esophagus and related lesions by laser capture microdissection.
Putative telomere-recruiting domain in the catalytic subunit of human telomerase.
Pyk2/ERK 1/2 mediate Sp1- and c-Myc-dependent induction of telomerase activity by epidermal growth factor.
Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G4-DNA Binder: A Solution and Solid-State Study.
Q&A: Elizabeth Blackburn on telomerase and tumors.
Quantification of alternative splicing variants of human telomerase reverse transcriptase and correlations with telomerase activity in lung cancer.
Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR.
Quantification of telomerase activity in normal oral mucosal tissue and oral squamous cell carcinoma.
Quantification of telomerase activity in sporadic colorectal carcinoma: association with tumor growth and venous invasion.
Quantification of telomerase activity of regions unstained with iodine solution that surround oral squamous cell carcinoma.
Quantifying interactions between G-quadruplex DNA and transition-metal complexes.
Quantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapy.
Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection.
Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay.
Quantitation of telomerase activity in hepatocellular carcinoma: a possible aid for a prediction of recurrent diseases in the remnant liver.
Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells.
Quantitative analysis of hTERT mRNA expression in colorectal cancer.
Quantitative analysis of hTERT mRNA levels in cells microdissected from cytological specimens.
Quantitative analysis of human telomerase reverse transcriptase in pancreatic cancer.
Quantitative analysis of telomerase activity and telomerase reverse transcriptase expression in renal cell carcinoma.
Quantitative analysis of telomerase activity and telomere length in domestic animal clones.
Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma.
Quantitative analysis of telomerase hTERT mRNA and telomerase activity in endometrioid adenocarcinoma and in normal endometrium.
Quantitative analysis of telomerase in feline mammary tissues.
Quantitative and spatial measurements of telomerase reverse transcriptase expression within normal and malignant human breast tissues.
Quantitative assay of telomerase activity in head and neck squamous cell carcinoma and other tissues.
Quantitative assays for measuring human telomerase activity and DNA binding properties.
Quantitative assessment of telomerase components in cancer cell lines.
Quantitative assessment of the diagnostic role of human telomerase activity from pancreatic juice in pancreatic cancer.
Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point.
Quantitative detection of disseminated cancer cells in the greater omentum of gastric carcinoma patients with real-time RT-PCR: a comparison with peritoneal lavage cytology.
Quantitative detection of telomerase activity by real-time TRAP assay in the body fluids of cancer patients.
Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol.
Quantitative determination of telomerase activity in breast cancer and benign breast diseases.
Quantitative differences in telomerase activity among malignant, premalignant, and benign ovarian lesions.
Quantitative evaluation of telomerase activity in small liver tumors: analysis of ultrasonography-guided liver biopsy specimens.
Quantitative measurement of telomerase activity and localization of its catalytic subunit (hTERT) in chronic inflammation of capsule formation around various model implants and in sarcomas in a rat model.
Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers.
Quantitative reevaluation of telomerase activity in cancerous and noncancerous gastrointestinal tissues.
Quantitative telomerase activity in malignant, benign and normal gynecological tissues.
Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution.
Quantitative telomerase expression in glioblastomas shows regional variation and down-regulation with therapy but no correlation with patient outcome.
Quantitative theory of telomere length regulation and cellular senescence.
Quencher group induced high specificity detection of telomerase in clear and bloody urines by AIEgens.
Radiation-induced changes of telomerase activity in a human Ewing xenograft tumor.
Radiation-induced effects on telomerase in gynecological cancer cell lines with different radiosensitivity and repair capacity.
Radiation-induced progressive decreasing in the expression of reverse transcriptase gene of hEST2 and telomerase activity.
Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines.
Radiogenomic Analysis of Papillary Thyroid Carcinoma for Prediction of Cervical Lymph Node Metastasis: A Preliminary Study.
Radiolabeled Oligonucleotides Targeting the RNA Subunit of Telomerase Inhibit Telomerase and Induce DNA Damage in Telomerase-Positive Cancer Cells.
Radiosensitization effect of zidovudine on human malignant glioma cells.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors.
Randomized phase II trial of All-trans-retinoic acid with chemotherapy based on paclitaxel and cisplatin as first-line treatment in patients with advanced non-small-cell lung cancer.
RAP1 moonlights to activate NF-?B and Notch in ALT.
Rapid blockade of telomerase activity and tumor cell growth by the DPL lipofection of ribbon antisense to hTR.
Rapid detection of MYCN gene amplification and telomerase expression in neuroblastoma.
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA.
Rapid progression of an IDH-wild type histological low-grade glioma harbouring TERT promoter mutation and diffuse CD34 expression: a case report.
Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide.
Rapid, quantitative nonisotopic assay for telomerase activity in human tumors.
Ratiometric Fluorescent Biosensor for Visual Discrimination of Cancer Cells with Different Telomerase Expression Levels.
Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
Rational Designed Bipolar, Conjugated Polymer-DNA Composite Beacon for the Sensitive Detection of Proteins and Ions.
Rb and E2F-1 regulate telomerase activity in human cancer cells.
RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma.
Re: Cancer cells in mesenteric vein and peripheral vessels by measuring telomerase activity in patients with colorectal cancer.
Re: TERT Promoter Mutations and Telomerase Reactivation in Urothelial Cancer.
Re: Yves Allorya, Willemien Beukers, Ana Sagrera, et al. Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome. Eur Urol 2014;65:360-6: Telomerase Expression and Stem Cells: Urologic Epithelial Perspective.
Reactivation of telomerase in cancer.
Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice.
Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip.
Real-time detection of telomerase activity using the exponential isothermal amplification of telomere repeat assay.
Real-time determination of telomerase activity in cell extracts using an optical biosensor.
Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment.
Real-time PCR detection of telomerase activity using specific molecular beacon probes.
Real-time PCR hTERT mRNA pattern in tumor core, edge, resection margin, and lymph nodes in laryngeal tumors: relation to proliferative index and impact on prognosis.
Real-time quantification in plasma of human telomerase reverse transcriptase (hTERT) mRNA: a simple blood test to monitor disease in cancer patients.
Real-time quantification of human telomerase reverse transcriptase mRNA in tumors and healthy tissues.
Real-time quantitative analysis for human telomerase reverse transcriptase mRNA and human telomerase RNA component mRNA expressions as markers for clinicopathologic parameters in urinary bladder cancer.
Real-time quantitative analysis of telomerase activity in breast tumor specimens using a highly specific and sensitive fluorescent-based assay.
Real-time quantitative PCR of telomerase mRNA is useful for the differentiation of benign and malignant pancreatic disorders.
Real-time quantitative RT-PCR for human telomere elongation reverse transcriptase in chronic myeloid leukemia.
Real-time quantitative telomeric repeat amplification protocol assay for the detection of telomerase activity.
Real-time RT-PCR quantification of human telomerase reverse transcriptase splice variants in tumor cell lines and non-small cell lung cancer.
Real-time telomerase activity measurements for detection of cancer.
Real-time telomerase assay of less-invasively collected esophageal cell samples.
Real-time telomeric repeat amplification protocol using the duplex scorpion and two reverse primers system: The high sensitive and accurate method for quantification of telomerase activity.
Real-Time, Quantitative Lighting-up Detection of Telomerase in Urines of Bladder Cancer Patients by AIEgens.
Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas.
Recent advances in targeting the telomeric G-quadruplex DNA sequence with small molecules as a strategy for anticancer therapies.
Recent advances in telomere biology: implications for human cancer.
Recent advances in the development of telomerase inhibitors for the treatment of cancer.
Recent advances in vertebrate aging research 2009.
Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.
Recent Developments in the Chemistry and Biology of G-Quadruplexes with Reference to the DNA Groove Binders.
Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications.
Recent Patents on Anti-Telomerase Cancer Therapy.
Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature.
Recent trends in cancer therapy: A review on the current state of gene delivery.
Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy.
Recognition and Stabilization of Quadruplex DNA by a Potent New Telomerase Inhibitor: NMR Studies of the 2:1 Complex of a Pentacyclic Methylacridinium Cation with d(TTAGGGT)(4) We thank the EPSRC of the UK and AstraZeneca for financial support to E.G. M.F.G.S. and R.A.H. are supported by the Cancer Research Campaign of the UK.
Recombinant lentivirus with enhanced expression of caudal-related homeobox protein 2 inhibits human colorectal cancer cell proliferation in vitro.
Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA.
Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells.
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT.
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span.
Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells.
Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeast.
Recurrent epimutations activate gene body promoters in primary glioblastoma.
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
Recurrent TERT promoter mutations in urothelial carcinoma and potential clinical applications.
Reduced expression of PinX1 correlates to progressive features in patients with prostate cancer.
Reduced integrin alpha3 expression as a factor of poor prognosis of patients with adenocarcinoma of the lung.
Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition.
Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor.
Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition.
Ref-1 protein enhances the IL-2-stimulated telomerase activity.
Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE.
Regression of gastric mucosa-associated lymphoid tissue lymphoma with reduced telomerase activity after eradication of Helicobacter pylori.
Regulation And Effect Of Telomerase And Telomeric Length In Stem Cells.
Regulation of catalytic activity and processivity of human telomerase.
Regulation of Cellular Immortalization and Steady-State Levels of the Telomerase Reverse Transcriptase through Its Carboxy-Terminal Domain.
Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis.
Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.
Regulation of human telomerase in homeostasis and disease.
Regulation of human telomerase splicing by RNA:RNA pairing.
Regulation of multiple energy transfer processes in a simple nano-system for sensitive telomerase detection.
Regulation of signal transduction cascades by Pterostilbenes in different cancers: Is it a death knell for oncogenic pathways.
Regulation of telomerase activity by apparently opposing elements.
Regulation of telomerase activity by the p53 family member p73.
Regulation of telomerase activity in immortal cell lines.
Regulation of telomerase activity in normal and malignant human cells.
Regulation of telomerase activity in quiescent immortalized human cells.
Regulation of telomerase alternative splicing: a target for chemotherapy.
Regulation of telomerase and its hTERT messenger in colorectal cancer.
Regulation of telomerase and telomeres: human tumor viruses take control.
Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium.
Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor.
Regulation of telomere length and homeostasis by telomerase enzyme processivity.
Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells.
Regulation of the human catalytic subunit of telomerase (hTERT).
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.
Regulation of the human telomerase reverse transcriptase gene.
Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms.
Regulation studies of telomerase gene in cancer cells by lentinan.
Regulatory mechanisms of human and mouse telomerase reverse transcriptase gene transcription: distinct dependency on c-Myc.
Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
Relation of MT1-MMP gene expression to outcomes in colorectal cancer.
Relationship between 3p deletions and telomerase activity in non-small-cell lung cancer: prognostic implications.
Relationship between dyskerin expression and telomerase activity in human breast cancer.
Relationship between expression of IGFBP7 and clinicopathological variables in gastric cancer.
Relationship between microvessel density and telomerase activity in hepatocellular carcinoma.
Relationship between RegIV gene expression to outcomes in colorectal cancer.
Relative contribution of normal and neoplastic cells determines telomerase activity and telomere length in primary cancers of the prostate, colon, and sarcoma.
Relative expression of human telomerase catalytic subunit (hTERT) transcripts in astrocytic gliomas.
Relevance and safety of telomerase for human tissue engineering.
Relevance of urine telomerase in the diagnosis of bladder cancer.
Reliability of quantitative reverse-transcriptase-PCR-based detection of tumour cells in the blood between different laboratories using a standardised protocol.
Reliable Förster Resonance Energy Transfer Probe Based on Structure-Switching DNA for Ratiometric Sensing of Telomerase in Living Cells.
Relief of p53-mediated telomerase suppression by p73.
Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer.
Renal cell carcinoma (RCC) and telomerase activity: relationship to stage.
Renoprotective Effects of Carbon Monoxide-Releasing Molecule 3 in Ischemia-Reperfusion Injury and Cisplatin-Induced Toxicity.
Replication of an adenoviral vector controlled by the human telomerase reverse transcriptase promoter causes tumor-selective tumor lysis.
Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres.
Replication stress as a source of telomere recombination during replicative senescence in Saccharomyces cerevisiae.
Replicative senescence and senescence-like state induced in cancer-derived cells.
Replicative senescence in sheep fibroblasts is a p53 dependent process.
Repression of human telomerase reverse transcriptase using artificial zinc finger transcription factors.
Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo.
Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer.
Requirement of E7 oncoprotein for viability of HeLa cells.
Resistance to telomerase inhibition by human squamous cell carcinoma cell lines.
Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.
Resveratrol down-regulates the growth and telomerase activity of breast cancer cells in vitro.
Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells.
Retinoblastoma and tumor-suppressor gene therapy.
Retinoic acid receptor alpha and retinoid-X receptor-specific agonists synergistically target telomerase expression and induce tumor cell death.
Retinoic acid suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma.
Retinoic acid-induced downmodulation of telomerase activity in human cancer cells.
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation.
Reverse transcriptase-polymerase chain reaction for expression of tyrosinase to identify malignant melanoma cells in peripheral blood.
Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells.
Reversible downregulation of telomerase activity by hyperthermia in osteosarcoma cells.
Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.
Revisiting Telomere Shortening in Cancer.
Rhodacyanine dye MKT-077 inhibits in vitro telomerase assay but has no detectable effects on telomerase activity in vivo.
Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition.
RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells.
Ribonucleic acid (RNA) biosynthesis in human cancer.
Ribozyme cleavage of telomerase mRNA sensitizes breast epithelial cells to inhibitors of topoisomerase.
Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells.
RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression.
RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line.
RNA interference mediated downregulation of human telomerase reverse transcriptase (hTERT) in LN18 cells.
RNA-dependent DNA polymerase activity in intracytoplasmic type-a particles of mouse mammary tumors.
RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase.
RNA-dependent DNA polymerase activity of RNA tumor viruses. I. Directing influence of DNA in the reaction.
RNA-dependent DNA polymerase activity of RNA tumor viruses. II. Directing influence of RNA in the reaction.
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells.
RNA-dependent DNA polymerase associated with equine infectious anemia virus.
RNA-dependent DNA polymerase in virions of RNA tumour viruses.
RNA-dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID-19.
RNAi gene therapy of SiHa cells via targeting human TERT induces growth inhibition and enhances radiosensitivity.
RNAi-hTERT Inhibition Hepatocellular Carcinoma Cell Proliferation via Decreasing Telomerase Activity.
RNase H and RNA-directed DNA polymerase: associated enzymatic activities of murine mammary tumor virus.
Rnr1's role in telomere elongation cannot be replaced by Rnr3: a role beyond dNTPs?
Robinin modulates TLR/NF-?B signaling pathway in oxidized LDL induced human peripheral blood mononuclear cells.
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.
Role of Apoptotic Regulators in Human Epithelial Ovarian Cancer.
Role of Cancer Stem Cell, Apoptotic Factor, DNA Repair, and Telomerase Toward Radiation Therapy Response in Stage IIIB Cervical Cancer.
Role of cytokines in cancer cachexia in a murine model of intracerebral injection of human tumours.
Role of diallyl disulfide-mediated cleavage of c-Myc and Sp-1 in the regulation of telomerase activity in human lymphoma cell line U937.
Role of DNA methylation and CpG sites in the viral telomerase RNA promoter during Gallid herpesvirus 2 pathogenesis.
Role of Ets/Id proteins for telomerase regulation in human cancer cells.
Role of GLTSCR2 in the regulation of telomerase activity and chromosome stability.
Role of HSPs and telomerase in radiotherapy.
Role of human telomerase reverse transcriptase and telomeric-repeat binding factor proteins 1 and 2 in human hematopoietic cells.
Role of interleukin-1beta and tumour necrosis factor-alpha in lipopolysaccharide-induced sickness behaviour: a study with interleukin-1 type I receptor-deficient mice.
Role of melatonin in the epigenetic regulation of breast cancer.
Role of menin in the regulation of telomerase activity in normal and cancer cells.
Role of mitochondria in carcinogenesis.
Role of shelterin in cancer and aging.
Role of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbeta.
Role of telomerase in anticancer activity of pristimerin in prostate cancer cells.
Role of telomerase in cell senescence and oncogenesis.
Role of telomerase in cellular proliferation and cancer.
Role of Telomerase in Cervical Lesions as Prognostic Marker: A Comparison Between Immunohistochemistry and FISH.
Role of telomerase in normal and cancer cells.
Role of telomerase in radiocurability (review).
Role of telomerase in the tumour microenvironment.
Role of Telomeres and Telomerase in Aging and Cancer.
Role of telomeres and telomerase in cancer.
Role of telomeres and telomerase in genomic instability, senescence and cancer.
Role of telomeres and telomerase in the pathogenesis of human cancer.
Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential.
Role of the ESCRT Complexes in Telomere Biology.
Role of the TRF2 Telomeric Protein in Cancer and Ageing.
Roles of NtGTBP1 in telomere stability.
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
RT-PCR evaluation of peripheral blood, bone marrow and peripheral blood stem cells in children and adolescents undergoing VACIME chemotherapy for Ewing's sarcoma and alveolar rhabdomyosarcoma.
Ruthenium-arene complexes bearing naphthyl-substituted 1,3-dioxoindan-2-carboxamides ligands for G-quadruplex DNA recognition.
RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle.
Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphoma.
Safety of umbilical cord blood-derived mesenchymal stem cells (MSCs) following 5-azaserine induction and inhibition of human cardiac myocyte apoptosis by MSCs.
Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells.
Sarcomatoid Renal Cell Carcinoma With Unusual Metastasis to the Small Intestine Manifesting as Perforated Appendicitis.
Screening of telomerase inhibitors.
Search for retrovirus-like particles in human breast cancer cells in culture.
Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells.
Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase-negative cells.
Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase.
Selective cytotoxicity and telomere damage in leukemia cells using the telomerase inhibitor BIBR1532.
Selective death of cancer cells by preferential induction of reactive oxygen species in response to (-)-epigallocatechin-3-gallate.
Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors.
Selective inhibition of human cancer cells by drugs which inhibit the RNA-dependent DNA polymerase enzyme.
Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines.
Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis.
Selective recognition of specific G-quadruplex vs. duplex DNA by a phenanthroline derivative.
Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity.
Semi-quantitative analysis of telomerase activity in exfoliated human urothelial cells and bladder transitional cell carcinoma.
Semi-quantitative analysis of telomerase activity of exfoliated cells in urine of patients with urothelial cancers: Causative factors affecting sensitivity and specificity.
Semi-quantitative procedure for telomeric repeat amplification protocol (TRAP) assay in colorectal carcinomas.
Semiquantitative analysis of telomerase activity in cervical cancer and precancerous lesions.
Sensing telomerase: From in vitro detection to in vivo imaging.
Sensitive and bidirectional detection of urine telomerase based on the four detection-color states of difunctional gold nanoparticle probe.
Sensitive and specific detection of circulating cancer cells in patients with hepatocellular carcinoma; detection of human telomerase reverse transcriptase messenger RNA after immunomagnetic separation.
Sensitive detection of intracellular RNA of human telomerase by using graphene oxide as a carrier to deliver the assembly element of hybridization chain reaction.
Sensitive detection of intracellular telomerase activity via double signal amplification and ratiometric fluorescence resonance energy transfer.
Sensitive detection of telomerase activity in cancer cells using portable pH meter as readout.
Sensitive detection of telomerase activity in cells using a DNA-based fluorescence resonance energy transfer nanoprobe.
Sensitive multicolor visual detection of telomerase activity based on catalytic hairpin assembly and etching of Au nanorods.
Sensitivity and specificity of NMP-22, telomerase, and BTA in the detection of human bladder cancer.
Sequence variation and mRNA expression of the TWIST1 gene in cats with mammary hyperplasia and neoplasia.
Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1.
Sequential 5-Aza-2'-deoxycytidine-Depsipeptide FR901228 Treatment Induces Apoptosis Preferentially in Cancer Cells and Facilitates Their Recognition by Cytolytic T Lymphocytes Specific for NY-ESO-1.
Sequential administration of the native TERT572 cryptic peptide enhances the immune response initiated by its optimized variant TERT(572Y) in cancer patients.
Serine/threonine-protein phosphatase 2A physically interacts with human telomerase reverse transcriptase hTERT and regulates its subcellular distribution.
SERS-based copper-mediated signal amplification strategy for simple and sensitive detection of telomerase activity.
Serum human telomerase reverse transcriptase messenger RNA as a novel tumor marker for hepatocellular carcinoma.
Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma.
Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infection.
Serum tumor markers for detection of hepatocellular carcinoma.
Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase.
Severe growth defect in mouse cells lacking the telomerase RNA component.
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Short hairpin ribonucleic acid targeting the telomerase catalytic unit of messenger ribonucleic acid significantly limits the growth of laryngeal squamous cell carcinoma in nude mice.
Short telomeres initiate telomere recombination in primary and tumor cells.
Short telomeres limit tumor progression in vivo by inducing senescence.
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies.
Shortened telomere length and increased telomerase activity in hamster pancreatic duct adenocarcinomas and cell lines.
Shorter telomeres and high telomerase activity correlate with a highly aggressive phenotype in breast cancer cell lines.
Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes.
ShRNA-mediated BMI-1 gene silencing inhibits gastrointestinal stromal tumor cell telomerase activity and enhances apoptosis.
shRNA-targeted hTERT suppress cell proliferation of bladder cancer by inhibiting telomerase activity.
Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells.
Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells.
Signal-On Dual-Potential Electrochemiluminescence Based on Luminol-Gold Bifunctional Nanoparticles for Telomerase Detection.
Signaling and transcriptional changes critical for transformation of human cells by simian virus 40 small tumor antigen or protein phosphatase 2A B56gamma knockdown.
Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastresophageal junction.
Signals controlling Cajal body assembly and function.
Significance of immunological detection of human telomerase reverse transcriptase: re-evaluation of expression and localization of human telomerase reverse transcriptase.
Significance of p53 expression in gastrointestinal stromal tumors.
Significant telomere reduction in human superficial transitional cell carcinoma.
Silencing of hTERT blocks growth and migration of anaplastic thyroid cancer cells.
Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients.
Silencing of the hTERT gene through RNA interference induces apoptosis via bax/bcl-2 in human glioma cells.
Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells.
Silencing tankyrase and telomerase promotes A549 human lung adenocarcinoma cell apoptosis and inhibits proliferation.
Silicon nanostructures for cancer diagnosis and therapy.
Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cells.
Simple and fast screening of G-quadruplex ligands with electrochemical detection system.
Simultaneous detection of telomerase and miRNA with graphene oxide-based fluorescent aptasensor in living cells and tissue samples.
Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach.
Single cell measurement of telomerase expression and splicing using microfluidic emulsion cultures.
Single clonal glandular stem cells derived from human parotid glands do not attain malignant phenotype during long-term in vitro culture.
Single living cell detection of telomerase over-expression for cancer detection by an optical fiber nanobiosensor.
Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines.
Single-Molecule Analysis of Human Telomere Sequence Interactions with G-quadruplex Ligand.
Single-molecule analysis of telomerase structure and function.
Single-molecule FRET-Rosetta reveals RNA structural rearrangements during human telomerase catalysis.
Single-Molecule Imaging of Telomerase RNA Reveals a Recruitment-Retention Model for Telomere Elongation.
Single-molecule real-time detection of telomerase extension activity.
Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs.
SiO2 nanoparticles modified CPE as a biosensor for determination of i-motif DNA/Tamoxifen interaction.
siRNA - Mediated LRP/LR knock-down reduces cellular viability of malignant melanoma cells through the activation of apoptotic caspases.
siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells.
siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells.
siRNA targeting LMP1-induced apoptosis in EBV-positive lymphoma cells is associated with inhibition of telomerase activity and expression.
siRNA-mediated inhibition of hTERT enhances chemosensitivity of hepatocellular carcinoma.
Sister chromatid separation at human telomeric regions.
Site on the RNA of an avian sarcoma virus at which primer is bound.
Sizing the ends: normal length of human telomeres.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Sleeping Beauty-mediated suicide gene therapy of hepatocellular carcinoma.
Slow-down of age-dependent telomere shortening is executed in human skin keratinocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidative stress.
SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.
SLX4IP N-terminus dictates telomeric localization in ALT-like castration-resistant prostate cancer cell lines.
Small Animal PET Imaging of hTERT RNA-Targeted HSV1-tk Gene Expression with Trans-Splicing Ribozyme.
Small nucleolar RNAs: versatile trans-acting molecules of ancient evolutionary origin.
Small-Molecule-Targeting Hairpin Loop of hTERT Promoter G-Quadruplex Induces Cancer Cell Death.
SMARCAL1 Resolves Replication Stress at ALT Telomeres.
Smart vesicle kit for in situ monitoring of intracellular telomerase activity using a telomerase-responsive probe.
Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells.
SnoopLigase peptide-peptide conjugation enables modular vaccine assembly.
Solid-Phase synthesis of a library constructed of aromatic phosphate, long alkyl chains and tryptophane components, and identification of potent dipeptide telomerase inhibitors.
Solitary fibrous tumors: loss of chimeric protein expression and genomic instability mark dedifferentiation.
Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas.
Soluble purified recombinant C2ORF40 protein inhibits tumor cell growth in vivo by decreasing telomerase activity in esophageal squamous cell carcinoma.
Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells.
Specific association of human telomerase activity with immortal cells and cancer.
Specific Binding of Anionic Porphyrin and Phthalocyanine to the G-Quadruplex with a Variety of in Vitro and in Vivo Applications.
Specific binding of telomeric G-quadruplexes by hydrosoluble perylene derivatives inhibits repeat addition processivity of human telomerase.
Specific expression of short-interfering RNA driven by human telomerase reverse transcriptase promoter in tumor cells.
Specific inhibition of human telomerase activity by transfection reagent, FuGENE6-antisense phosphorothioate oligonucleotide complex in HeLa cells.
Specific regression of human cancer cells by ribozyme-mediated targeted replacement of tumor-specific transcript.
Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells.
Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer.
Spinal cord long-term potentiation (LTP) is associated with increased dorsal horn gene expression of IL-1beta, GDNF and iNOS.
Spindle cell liposarcoma with a TRIO-TERT fusion transcript.
Spindle cells from AIDS-associated Kaposi's sarcoma lesions express telomerase activity that is enhanced by Kaposi's sarcoma progression factors.
Spinonin, a novel glycoside from Ononis spinosa subsp. leiosperma.
Spontaneous neoplastic regression: the significance of apoptosis.
Spontaneous regression of neoplasms: new possibilities for immunotherapy.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Stabilisation of G-quadruplex DNA by small molecules.
Stability and free energy calculation of LNA modified quadruplex: a molecular dynamics study.
Stabilization of c-myc G-Quadruplex DNA, inhibition of telomerase activity, disruption of mitochondrial functions and tumor cell apoptosis by platinum(II) complex with 9-amino-oxoisoaporphine.
Stabilization of G-quadruplex DNA and inhibition of telomerase activity studies of ruthenium(II) complexes.
Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity and Live Cell Imaging Studies of Chiral Ruthenium(II) Complexes.
Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Tumor Cell Apoptosis by Organoplatinum(II) Complexes with Oxoisoaporphine.
Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase.
Stable expression in a Chinese hamster ovary (CHO) cell line of bioactive recombinant chelonianin, which plays an important role in protecting fish against pathogenic infection.
Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype.
Standards for validation of cancer biomarkers.
Stem cell function and maintenance - ends that matter: Role of telomeres and telomerase.
Stem cells, telomerase and dyskeratosis congenita.
Stilbene Compounds Inhibit Tumor Growth by the Induction of Cellular Senescence and the Inhibition of Telomerase Activity.
STRATEGIES OF TREATING CANCER BY CYTOKINE REGULATION OF CHROMOSOME END REMODELLING.
Strategies targeting telomerase inhibition.
Stress-induced premature senescence (SIPS).
Strong antigen-specific T-cell immunity induced by a recombinant human TERT measles virus vaccine and amplified by a DNA/viral vector prime boost in IFNAR/CD46 mice.
Structural and biophysical insight into dual site binding of the protoberberine alkaloid palmatine to parallel G-quadruplex DNA using NMR, fluorescence and Circular Dichroism spectroscopy.
Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
Structural diversity and specific recognition of four stranded G-quadruplex DNA.
Structural insights into a wildtype domain of the oncoprotein E6 and its interaction with a PDZ domain.
Structural, functional, and stability change predictions in human telomerase upon specific point mutations.
Structure of human telomerase holoenzyme with bound telomeric DNA.
Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Structure of the vault, a ubiquitous celular component.
Structure-activity relationships among guanine-quadruplex telomerase inhibitors.
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors.
Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology.
Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme.
Structure-function relationships in telomerase genes.
Structures of telomerase at several steps of telomere repeat synthesis.
Studies of the molecular mechanisms in the regulation of telomerase activity.
Study of hTERT and Histone 3 Mutations in Medulloblastoma.
Study of telomerase activity in pleural lavage fluid specimens in patients with non-small-cell lung cancer and its clinical significance.
Study of the expressions of p53 and bcl-2 genes, the telomerase activity and apoptosis in GIST patients.
Sublethal hemorrhage blunts the inflammatory cytokine response to endotoxin in a rat model.
Subnuclear shuttling of human telomerase induced by transformation and DNA damage.
Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells.
Successful pre-operative diagnosis of malignant intraductal papillary mucinous tumor of the pancreas by detecting telomerase activity.
Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2.
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.
Suppressing orthotopic pancreatic tumor growth with a fiber-modified adenovector expressing the TRAIL gene from the human telomerase reverse transcriptase promoter.
Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.
Suppression of cancer growth in mice by adeno-associated virus vector-mediated IFN-beta expression driven by hTERT promoter.
Suppression of cell proliferation and telomerase activity in 4-(hydroxyphenyl)retinamide-treated mammary tumors.
Suppression of hPOT1 in Diploid Human Cells Results in an hTERT-Dependent Alteration of Telomere Length Dynamics.
Suppression of Ku80 Correlates with Radiosensitivity and Telomere Shortening in the U2OS Telomerase-negative Osteosarcoma Cell Line.
Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-?B.
Suppression of PinX1 resulted in telomere dysfunction and enhanced radiosensitivity in osteosarcoma cell lines.
Suppression of PROX1-mediated TERT expression in hepatitis B viral hepatocellular carcinoma.
Suppression of telomerase activity as an indicator of drug-induced cytotoxicity against cancer cells: in vitro studies with fresh human tumor samples.
Suppression of telomerase activity by pyrimethamine: implication to cancer.
Suppression of telomerase, reexpression of KAI1, and abrogation of tumorigenicity by nerve growth factor in prostate cancer cell lines.
Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.
Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells.
Suramin increased telomerase activity in the c6 glioma/wistar experimental brain tumor model.
Surgical significance of telomerase activity in noncancerous liver tissue from patients with hepatocellular carcinoma.
Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis.
Survival of diffuse astrocytic glioma, IDH1/2-wildtype, with molecular features of glioblastoma, WHO grade IV: a confirmation of the cIMPACT-NOW criteria.
Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation.
Survivin and telomerase expression in the uterine cervix of women with human papillomavirus-induced lesions.
Survivin enhances telomerase activity via up-regulation of specificity protein 1- and c-Myc-mediated human telomerase reverse transcriptase gene transcription.
Survivin in glioblastomas. Protein and messenger RNA expression and comparison with telomerase levels.
Surviving Telomere Attrition with the MiDAS Touch.
Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus.
SV40 infection induces telomerase activity in human mesothelial cells.
Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX.
Switching Off Cancer-Causing Telomerase Using Small Molecules.
Synergic effect of 3'-azido-3'-deoxythymidine and arsenic trioxide in suppressing hepatoma cells.
Synergistic antitumoral effects of human telomerase reverse transcriptase-mediated dual-apoptosis-related gene vector delivered by orally attenuated Salmonella enterica Serovar Typhimurium in murine tumor models.
Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113).
Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line.
Synergistic Effects of Resistin and Visfatin as Adipocyte Derived Hormones on Telomerase Gene Expression in AGS Gastric Cancer Cell Line.
Synergistic Interaction of Telomerase-Specific Oncolytic Virotherapy and Chemotherapeutic Agents for Human Cancer.
Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A.
Synergy between 3'-azido-3'-deoxythymidine and paclitaxel in human pharynx FaDu cells.
Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids.
Synthesis and discovery of 18?-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65.
Synthesis and human telomerase inhibition of a series of regioisomeric disubstituted amidoanthraquinones.
Synthesis of 6-formyl-pyridine-2-carboxylate derivatives and their telomerase inhibitory activities.
Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors.
Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,11-dione homologues.
Synthesis, G-Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2-b]quinolines with One, Two, or Three Basic Side Chains.
Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives.
Synthesis, molecular modeling and biological evaluation of N-benzylidene-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetohydrazide derivatives as potential anticancer agents.
Synthetic 2'-O-methyl-modified hammerhead ribozymes targeted to the RNA component of telomerase as sequence-specific inhibitors of telomerase activity.
Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.
Synthetic nucleosides and nucleotides. 43. Inhibition of vertebrate telomerases by carbocyclic oxetanocin g (C.OXT-G) triphosphate analogues and influence of C.OXT-G treatment on telomere length in human HL60 cells.
Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy.
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Systematic review of genetic variation in chromosome 5p15.33 and telomere length as predictive and prognostic biomarkers for lung cancer.
T and B cells in B-chronic lymphocytic leukaemia: Faust, Mephistopheles and the pact with the Devil.
T cell receptor Vbeta repertoire of tumour-infiltrating lymphocytes in oral squamous-cell carcinoma.
T cell-based targeted immunotherapies for patients with multiple myeloma.
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy.
Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
Target expression of Staphylococcus enterotoxin A from an oncolytic adenovirus suppresses mouse bladder tumor growth and recruits CD3+ T cell.
Target induced framework nucleic acid nanomachine with doxorubicin-spherical nucleic acid tags for electrochemical determination of human telomerase activity.
Target-controlled in situ formation of G-quadruplex DNAzyme for a sensitive visual assay of telomerase activity.
Targeted anticancer effect through microRNA-181a regulated tumor-specific hTERT replacement.
Targeted antitumor effect induced by hTERT promoter mediated ODC antisense adenovirus.
Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo.
Targeted Covalent Inhibition of Telomerase.
Targeted expression of green fluorescent protein/tumor necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumor activity without toxic effects on primary human hepatocytes.
Targeted inhibition of telomerase activity combined with chemotherapy demonstrates synergy in eliminating ovarian cancer spheroid-forming cells.
Targeted inhibition of telomerase in human cancer: will it be a double-edged sword?
Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3'-UTR microRNA.
Targeted therapy of human laryngeal squamous cell carcinoma in vitro by antisense oligonucleotides directed against telomerase reverse transcriptase mRNA.
Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA.
Targeted Tumor Therapy Remixed-An Update on the Use of Small-Molecule Drugs in Combination Therapies.
Targeting ALT: the role of alternative lengthening of telomeres in pathogenesis and prevention of cancer.
Targeting antitumor CD4 helper T cells with universal tumor-reactive helper peptides derived from telomerase for cancer vaccine.
Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity.
Targeting cancer with telomerase: commentary re Q. Huang et al., a novel conditionally replicative adenovirus vector targeting telomerase-positive tumor cells. Clin. Cancer Res., 10: 1439-1445, 2004.
Targeting cell cycle by ?-carboline alkaloids in vitro: Novel therapeutic prospects for the treatment of cancer.
Targeting claudin-4 in human pancreatic cancer.
Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists.
Targeting DNA quadruplexes with distamycin A and its derivatives: an ITC and NMR study.
Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.
Targeting human telomerase by antisense oligonucleotides and ribozymes.
Targeting human telomerase for cancer therapeutics.
Targeting human telomerase in cancer therapy.
Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo.
Targeting human telomerase RNA component using antisense oligonucleotide induces rapid cell death and increases ATO-induced apoptosis in APL cells.
Targeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+).
Targeting pancreatic cancer with a G-quadruplex ligand.
Targeting telomerase activity by BIBR1532 as a therapeutic approach in germ cell tumors.
Targeting Telomerase and ATRX/DAXX Inducing Tumor Senescence and Apoptosis in the Malignant Glioma.
Targeting telomerase and telomeres to enhance ionizing radiation effects in in vitro and in vivo cancer models.
Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands.
Targeting telomerase by antisense-based approaches: perspectives for new anti-cancer therapies.
Targeting telomerase for cancer therapeutics.
Targeting telomerase for cancer therapy.
Targeting telomerase for its advent in cancer therapeutics.
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy.
Targeting telomerase with radiolabeled inhibitors.
TARGETING TELOMERASE-EXPRESSING CANCER CELLS.
Targeting telomerase.
Targeting telomerase: T-cell friendly fire.
Targeting telomeres and telomerase.
Targeting the limitless replicative potential of cancer: the telomerase/telomere pathway.
Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma.
Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells.
Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.
Targeting the telosome: Therapeutic implications.
TCAB1: driving telomerase to Cajal bodies.
TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression.
TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes.
TCTP overexpression reverses age-associated telomere attrition by upregulating telomerase activity in mouse oocytes.
Technical aspects of minimal residual disease detection in carcinoma patients.
Technical improvement in determining telomerase activity in hematologic neoplasias: a possibility of single cell determination of telomerase activity.
TelNet - a database for human and yeast genes involved in telomere maintenance.
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells.
Telomerase - strategies to exploit an important chemotherapeutic target.
Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis.
Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma.
Telomerase activation and cancer.
Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid.
Telomerase activation and incidence of HPV in human gastrointestinal tumors in North Indian population.
Telomerase activation and p53 mutations in urethane-induced A/J mouse lung tumor development.
Telomerase activation as a possible mechanism of action for psychopharmacological interventions.
Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes.
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Telomerase activation by histone deacetylase inhibitor in normal cells.
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas.
Telomerase activation by the E6 gene product of human papillomavirus type 16.
Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension.
Telomerase activation cooperates with inactivation of p16 in early head and neck tumorigenesis.
Telomerase activation during the linear evolution of human fibroblasts to tumorigenicity in nude mice.
Telomerase activation in a model of lung adenocarcinoma.
Telomerase activation in cervical cancer.
Telomerase activation in cervical neoplasia.
Telomerase activation in colorectal carcinogenesis.
Telomerase activation in endometrial epithelial cells by paracrine effectors from stromal cells in primary cultured human endometrium.
Telomerase Activation in Hematological Malignancies.
Telomerase activation in human cancers.
Telomerase activation in human hepatocarcinogenesis.
Telomerase activation in in vitro and in vivo cervical carcinogenesis.
Telomerase activation in liver regeneration and hepatocarcinogenesis: Dr. Jekyll or Mr. Hyde?
Telomerase Activation in Malignant Bone Tumors.
Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.
Telomerase activation in nasopharyngeal carcinomas.
Telomerase activation in neoplastic cell immortalization and tumour progression.
Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas.
Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain.
Telomerase activation in the treatment of aging or degenerative diseases: a systematic review.
Telomerase activation without shortening of telomeric 3'-overhang is a poor prognostic factor in human colorectal cancer.
Telomerase activation, cellular immortalization and cancer.
Telomerase activation--one step on the road to carcinoma of the gall bladder.
Telomerase activation. One step on the road to cancer?
Telomerase activity (TMA) in tumour and peritumoural tissues in a rat liver cancer model.
Telomerase Activity Analysis In Urine Sediment for Bladder Cancer.
Telomerase activity analysis of esophageal carcinoma using microdissection-TRAP assay.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and Bcl-2 expression in gallbladders of pancreaticobiliary maljunction patients: a preliminary study.
Telomerase activity and Bcl-2 expression in human breast cancer.
Telomerase activity and Bcl-2 expression in non-small cell lung cancer.
Telomerase activity and cell proliferation index in cholesteatoma.
Telomerase activity and clinical progression in chronic lymphoproliferative disorders of B-cell lineage.
Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression.
Telomerase activity and cytokeratin 20 as markers for the detection and followup of transitional cell carcinoma: an unfulfilled promise.
Telomerase activity and expression in adult human mesenchymal stem cells derived from amyotrophic lateral sclerosis individuals.
Telomerase activity and expression of apoptosis and anti-apoptosis regulators in the progression pathway of human melanoma.
Telomerase Activity and Expression of hTR and TERT in Human Soft Tissue Sarcomas.
Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.
Telomerase activity and expression of human telomerase catalytic subunit gene in esophageal tissues.
Telomerase activity and expression of telomerase reverse transcriptase correlated with cell proliferation in meningiomas and malignant brain tumors in vivo.
Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer.
Telomerase activity and expression of the telomerase catalytic subunit gene in non-small cell lung cancer: correlation with decreased apoptosis and clinical prognosis.
Telomerase activity and expression of the telomerase catalytic subunit, hTERT, in meningioma progression.
Telomerase activity and genetic alterations in primary breast carcinomas.
Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma.
Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas.
Telomerase activity and hTERT mRNA expression in body fluids.
Telomerase activity and hTERT mRNA expression in glial tumors.
Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer.
Telomerase activity and hTERT protein expression in meningiomas: an analysis in vivo versus in vitro.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity and human telomerase reverse transcriptase mRNA expression are correlated with clinical aggressiveness in soft tissue tumors.
Telomerase activity and human telomerase reverse transcriptase mRNA expression in soft tissue tumors: correlation with grade, histology, and proliferative activity.
Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes.
Telomerase activity and its clinicopathological significance in gastric cancer.
Telomerase activity and its inhibition in benign and malignant breast lesions.
Telomerase activity and lymphovascular invasion in breast cancer.
Telomerase activity and metastasis: expansion of cells having higher telomerase activity within culture lines and tumor tissues.
Telomerase activity and microsatellite instability in colorectal cancer and adenoma.
Telomerase activity and Nm23-H2 protein expression in hepatocellular carcinoma.
Telomerase activity and oncogenesis in giant cell tumor of bone.
Telomerase activity and patient survival after surgery for gastric and oesophageal cancer.
Telomerase activity and phenotypic characterization in harvested bone marrow from a child with a germline cell cancer.
Telomerase activity and prognosis in breast cancer.
Telomerase activity and prognosis in primary breast cancers.
Telomerase activity and proliferation index in aggressive mature B-cell lymphoma: comparison to germinal center phenotypic markers.
Telomerase activity and serum levels of p53 protein as prognostic factors of survival in patients with advanced non-small cell lung cancer.
Telomerase activity and survival of late-stage South African esophageal carcinoma patients.
Telomerase activity and survival of patients with node-positive breast cancer.
Telomerase activity and telomerase catalytic subunit in hepatocellular carcinoma.
Telomerase activity and telomerase reverse transcriptase catalytic subunit expression in canine lymphoma: correlation with Ki67 immunoreactivity.
Telomerase activity and telomerase subunit gene expression levels are not related in prostate cancer: a real-time quantification and in situ hybridization study.
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia.
Telomerase activity and telomere length in benign and malignant human thyroid tissues.
Telomerase activity and telomere length in different areas of renal cell carcinoma.
Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease.
Telomerase activity and telomere length in human hepatocellular carcinoma.
Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents.
Telomerase activity and telomere length in human tumor cells with acquired resistance to anticancer agents.
Telomerase activity and telomere length in lymphocytes from patients with cutaneous T-cell lymphoma.
Telomerase activity and telomere length in patients with acute promyelocytic leukemia: indicative of proliferative activity, disease progression, and overall survival.
Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy.
Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients.
Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence.
Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications.
Telomerase activity and telomere lengths in various cell lines: changes of telomerase activity can be another method for chemosensitivity evaluation.
Telomerase activity and telomere lengths: alterations in renal cell carcinomas.
Telomerase activity and the expression of telomerase components in pituitary adenoma with malignant transformation.
Telomerase activity and the subunit of telomerase in hydatidiform mole and their relationship with the development of postmolar tumor.
Telomerase activity as a biological marker in some gynecological tumors: comparison with tissue and serum CA 125.
Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smear.
Telomerase activity as a marker for malignancy in feline tissues.
Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples.
Telomerase activity as a measure for monitoring radiocurability of tumor cells.
Telomerase activity as a novel marker of lung cancer and immune-associated lung diseases.
Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears.
Telomerase activity as a potential marker in preneoplastic bladder lesions.
Telomerase activity as a predictive marker for recurrence of hepatocellular carcinoma after hepatectomy.
Telomerase activity as a prognostic factor in colorectal cancer.
Telomerase activity as a prognostic factor in neuroblastomas.
Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer.
Telomerase activity as a tumor marker in Indian women with cervical intraepithelial neoplasia and cervical cancer.
Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer.
Telomerase activity as an indicator of malignant potential in iodine-nonreactive lesions of the esophagus.
Telomerase activity as an indicator of potentially malignant adrenal tumors.
Telomerase activity as prognostic factor in gastrointestinal stromal tumors of the stomach.
Telomerase activity associated with acquisition of malignancy in human colorectal cancer.
Telomerase activity by TRAP assay and telomerase RNA (hTR) expression are predictive of outcome in neuroblastoma.
Telomerase activity coevolves with body mass not lifespan.
Telomerase activity correlates with cell cycle regulators in human hepatocellular carcinoma.
Telomerase activity correlates with growth of transplantable osteosarcomas in rats treated with cis-diammine dichloroplatinum or the angiogenesis inhibitor AGM-1470.
Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma.
Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer.
Telomerase activity could be used as a marker for neoplastic transformation in gastric adenocarcinoma: but it does not have a prognostic significance.
Telomerase activity detected by quantitative assay in bladder carcinoma and exfoliated cells in urine.
Telomerase activity detected in pancreatic juice 19 months before a tumor is detected in a patient with pancreatic cancer.
Telomerase Activity Detection with Amplification-Free Single Molecule Stochastic Binding Assay.
Telomerase activity determined by conventional telomeric repeat amplification protocol and reverse transcriptase-polymerase chain reaction assay in ovarian lesions: a comparison of assays.
Telomerase activity distinguishes between neuroblastomas with good and poor prognosis.
Telomerase activity during carcinogenesis in the bronchus.
Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts.
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA.
Telomerase activity in "suspicious" thyroid cytology.
Telomerase activity in 144 brain tumours.
Telomerase activity in a specific cell subset co-expressing integrinbeta1/EGFR but not p75NGFR/bcl2/integrin beta4 in normal human epithelial cells.
Telomerase activity in adrenal cortical tumors and pheochromocytomas with reference to clinicopathologic features.
Telomerase activity in B-cell non-Hodgkin lymphoma.
Telomerase activity in benign and malignant adrenal tumors.
Telomerase activity in benign and malignant cytologic fluids.
Telomerase activity in benign and malignant epithelial ovarian tumors.
Telomerase activity in benign and malignant human thyroid tissues.
Telomerase activity in benign and malignant thyroid diseases.
Telomerase activity in benign and malignant thyroid tumors.
Telomerase activity in benign bone tumors and tumor-like lesions.
Telomerase activity in benign endometrium and endometrial carcinoma.
Telomerase activity in bilharzial bladder cancer. Prognostic implications.
Telomerase activity in bladder cancer tissue.
Telomerase activity in bladder cancer, bladder washings and in urine.
Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine.
Telomerase activity in body cavity fluid and peritoneal washings in uterine and ovarian cancer.
Telomerase activity in breast cancer in Western India (Gujarat).
Telomerase activity in breast cancer patients: association with poor prognosis and more aggressive phenotype.
Telomerase activity in cancer as a diagnostic and therapeutic target.
Telomerase activity in cancer: a magic bullet or a mirage?
Telomerase activity in candidate stem cells from fetal liver and adult bone marrow.
Telomerase activity in canine osteosarcoma.
Telomerase activity in cell lines and lymphoma originating from Bloom syndrome.
Telomerase activity in cell lines of pediatric soft tissue sarcomas.
Telomerase activity in central nervous system malignant lymphoma.
Telomerase activity in cervical cancer is quantitatively distinct from that in its precursor lesions.
Telomerase activity in cervical intraepithelial neoplasia.
Telomerase activity in chronic inflammatory bowel disease.
Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage.
Telomerase activity in clinically normal dogs and dogs with malignant lymphoma.
Telomerase activity in colorectal cancer and its relationship to bcl-2 expression.
Telomerase activity in colorectal cancer, prognostic factor and implications in the microsatellite instability pathway.
Telomerase activity in connective tissue diseases: elevated in rheumatoid arthritis, but markedly decreased in systemic sclerosis.
Telomerase activity in diagnosis of bladder cancer.
Telomerase activity in different clinical staging of colorectal adenocarcinoma.
Telomerase activity in disseminated prostate cancer cells.
Telomerase activity in ductal carcinoma in situ and invasive breast cancer.
Telomerase activity in ductal carcinoma in situ of the breast.
Telomerase activity in esophageal squamous cell carcinoma and lesions unstained with Lugol's solution.
Telomerase activity in esophageal squamous cell carcinoma: down-regulation by chemotherapeutic agent.
Telomerase activity in experimental animal tumors.
Telomerase Activity in Gastric Adenocarcinomas: Frozen Tissues Versus Methacarn-fixed Paraffin-embedded Tissues.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in gastric cancer.
Telomerase activity in gastrointestinal stromal tumors.
Telomerase activity in germ cell cancers and mature teratomas.
Telomerase activity in giant cell tumors of bone.
Telomerase activity in giant condyloma acuminatum.
Telomerase activity in gliomas with the use of non-radioisotopic and semi-quantitative procedure for terminal repeat amplification protocol.
Telomerase activity in gynecologic tumors.
Telomerase activity in gynecological tumors.
Telomerase activity in head and neck cancer.
Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.
Telomerase activity in head and neck tumors after introduction of wild-type p53, p21, p16, and E2F-1 genes by means of recombinant adenovirus.
Telomerase activity in HeLa cervical carcinoma cell line proliferation.
Telomerase activity in hepatocellular carcinoma and adjacent liver tissues.
Telomerase activity in hepatocellular carcinoma as a predictor of postoperative recurrence.
Telomerase activity in Hodgkin's disease.
Telomerase activity in human acute myelogenous leukemia: inhibition of telomerase activity by differentiation-inducing agents.
Telomerase activity in human benign prostate tissue and prostatic adenocarcinomas.
Telomerase activity in human bladder cancer.
Telomerase activity in human bladder tumors and bladder washing specimens.
Telomerase Activity in Human Brain Tumors: Astrocytoma and Meningioma.
Telomerase activity in human brain tumours.
Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.
Telomerase activity in human breast tumors.
Telomerase activity in human cancer.
Telomerase activity in human germline and embryonic tissues and cells.
Telomerase activity in human gliomas.
Telomerase activity in human gynaecological malignancies.
Telomerase activity in human intestine.
Telomerase activity in human laryngeal squamous cell carcinomas.
Telomerase activity in human leukemic cells with or without monosomy 7 or 7q-.
Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.
Telomerase activity in human ovarian carcinoma.
Telomerase activity in human pleural mesothelioma.
Telomerase activity in human proliferative breast lesions.
Telomerase activity in human renal cell carcinoma.
Telomerase activity in human solid tumors. Diagnostic utility and clinical applications.
Telomerase activity in human thyroid carcinomas originating from the follicular cells.
Telomerase activity in human urothelial tumors.
Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis.
Telomerase activity in Indian patients with carcinomas of the aerodigestive tract.
Telomerase activity in juxtacortical and conventional high-grade osteosarcomas: correlation with grade, proliferative activity and clinical response to chemotherapy.
Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.
Telomerase activity in lesions of the thyroid: application to diagnosis of clinical samples including fine-needle aspirates.
Telomerase activity in long-standing ulcerative colitis.
Telomerase activity in lung cancer cell lines and tissues.
Telomerase activity in Malaysian patients with central nervous system tumors.
Telomerase activity in malignant and benign bladder conditions.
Telomerase activity in malignant and benign renal tumors.
Telomerase activity in malignant ovarian tumors with deregulation of cell cycle regulatory proteins.
Telomerase activity in melanocytic lesions: A potential marker of tumor biology.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase activity in microdissected human breast cancer tissues: association with p53, p21 and outcome.
Telomerase activity in microdissected human gliomas.
Telomerase activity in myeloma cells is closely related to cell cycle status, but not to apoptotic signals induced by interferon-alpha.
Telomerase activity in needle biopsied uterine myoma-like tumors: differential diagnosis between uterine sarcomas and leiomyomas.
Telomerase activity in needle biopsies from prostate cancer and benign prostates.
Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour?
Telomerase activity in neuroendocrine tumors.
Telomerase activity in non-small cell lung cancer.
Telomerase activity in non-small cell lung carcinomas correlates with smoking status.
Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy.
Telomerase activity in normal and malignant murine tissues.
Telomerase activity in normal and neoplastic breast.
Telomerase activity in normal human endothelial cells.
Telomerase activity in normal human epithelial cells.
Telomerase activity in normal leukocytes and in hematologic malignancies.
Telomerase activity in oral and maxillofacial tumors.
Telomerase activity in oral cancer.
Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma.
Telomerase activity in oral squamous cell carcinoma.
Telomerase activity in ordinary meningiomas predicts poor outcome.
Telomerase activity in ovarian tumors.
Telomerase activity in pancreatic endocrine tumors.
Telomerase activity in pancreatic endocrine tumours: a potential marker for malignancy.
Telomerase activity in patients with chronic myeloid leukemia and lymphoma.
Telomerase activity in patients with transitional cell carcinoma: a preliminary study.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity in peripheral blood mononuclear cells of systemic connective tissue diseases.
Telomerase activity in Philadelphia positive chronic myeloid leukaemia.
Telomerase activity in phyllodes tumours.
Telomerase activity in pituitary adenomas: significance of telomerase expression in predicting pituitary adenoma recurrence.
Telomerase activity in pleural malignant mesotheliomas.
Telomerase activity in precancerous hepatic nodules.
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Telomerase activity in primary and secondary glioblastomas multiforme as a novel molecular tumor marker.
Telomerase activity in primary prostate cancer.
Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium.
Telomerase activity in prostate sextant needle cores from radical prostatectomy specimens.
Telomerase activity in proximal and distal gastric neoplastic and preneoplastic lesions using immunohistochemical detection of hTERT.
Telomerase activity in radiation-induced chronic human skin ulcers.
Telomerase activity in reactive and neoplastic lymphoid tissues: infrequent detection of activity in Hodgkin's disease.
Telomerase activity in relation to p53 status and clinico-pathological parameters in breast cancer.
Telomerase activity in renal cell carcinoma.
Telomerase activity in sex cord-stromal tumors of the ovary.
Telomerase activity in skeletal sarcomas.
Telomerase activity in small cell esophageal carcinoma.
Telomerase activity in small-cell and non-small-cell lung cancers.
Telomerase activity in soft-tissue and bone sarcomas.
Telomerase activity in solid transitional cell carcinoma, bladder washings, and voided urine.
Telomerase activity in sputum and telomerase and its components in biopsies of advanced lung cancer.
Telomerase activity in stage II colorectal carcinoma.
Telomerase activity in surgical specimens and fine-needle aspiration biopsies from hyperplastic and neoplastic human thyroid tissues.
Telomerase activity in the differential diagnosis of pancreatic mass.
Telomerase activity in the differentiation of benign and malignant adrenal tumors.
Telomerase activity in the female reproductive tract and neoplasms.
Telomerase activity in the human breast.
Telomerase activity in the normal and neoplastic rat mammary gland.
Telomerase activity in the occurrence and progression of oral squamous cell carcinoma.
Telomerase activity in the synovial tissues of chronic inflammatory and non-inflammatory rheumatic diseases.
Telomerase activity in the vaginal margins of radical hysterectomy in patients with carcinoma of the cervix: correlation with histology and human papillomavirus.
Telomerase activity in thymomas and mammary gland adenocarcinomas induced by polyoma virus in AKR mice.
Telomerase activity in thyroid malignancy.
Telomerase activity in thyroid tumors.
Telomerase activity in touch-imprint cell preparations from fresh prostate needle biopsy specimens.
Telomerase activity in transthoracic fine needle biopsy aspirates as a marker of peripheral lung cancer.
Telomerase activity in transthoracic fine-needle biopsy aspirates from non-small cell lung cancer as prognostic factor of patients' survival.
Telomerase activity in tumor and remnant liver as predictor of recurrence and survival in hepatocellular carcinoma after resection.
Telomerase activity in urine after transurethral resection of superficial bladder cancer and early recurrence.
Telomerase activity in urine in diagnosis and recurrence surveillance of urothelial carcinoma.
Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer.
Telomerase activity in vivo in human malignant hematopoietic cells.
Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.
Telomerase activity is a prognostic factor for recurrence and survival in rectal cancer.
Telomerase activity is a useful marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts.
Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription.
Telomerase activity is associated with cell cycle deregulation in human breast cancer.
Telomerase activity is commonly detected in hereditary nonpolyposis colorectal cancers.
Telomerase activity is detected in pancreatic cancer but not in benign tumors.
Telomerase activity is frequently found in metaplastic and malignant human nasopharyngeal tissues.
Telomerase activity is maintained throughout the lifespan of long-lived birds.
Telomerase activity is not altered by regular strenuous exercise in skeletal muscle or by sarcoma in liver of rats.
Telomerase activity is repressed during differentiation of maturation-sensitive but not resistant human tumor cell lines.
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase.
Telomerase activity is significantly enhanced in malignant adrenocortical tumors in comparison to benign adrenocortical adenomas.
Telomerase activity is upregulated in laryngeal squamous cell carcinoma.
Telomerase activity levels for evaluating the surgical margin in breast-conserving surgery.
Telomerase activity levels in the surgical margin and tumour distant tissue of the squamous cell carcinoma of the head-and-neck.
Telomerase activity measurement in magnetically captured epithelial cells: comparison of slab-gel and capillary electrophoresis.
Telomerase activity modulation in the prevention of prostate cancer.
Telomerase activity of blood samples and recurrence of colorectal cancer.
Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion.
Telomerase activity of Merkel cell carcinomas and Merkel cell carcinoma-derived cell cultures.
Telomerase activity of needle-biopsied liver samples: its usefulness for diagnosis and judgement of efficacy of treatment of small hepatocellular carcinoma.
Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues.
Telomerase activity of sarcoma cell lines and fibroblasts is independent of p53 status.
Telomerase activity of the Lugol-stained and -unstained squamous epithelia in the process of oesophageal carcinogenesis.
Telomerase activity predicts malignancy in percutaneous image-guided needle biopsy specimens of the abdomen and pelvis.
Telomerase activity significantly correlates with chromosome alterations, cell differentiation, and proliferation in lung adenocarcinomas.
Telomerase activity Simplification of assay and detection in bladder tumor and urinary exfoliated cells.
Telomerase activity with concurrent loss of cell cycle regulation in feline post-traumatic ocular sarcomas.
Telomerase activity, and tissue polypeptide specific antigen (TPS) in Egyptian breast cancer patients.
Telomerase activity, cell proliferation, and cancer.
Telomerase activity, cytokeratin 20 and cytokeratin 19 in urine cells of bladder cancer patients.
Telomerase activity, estrogen receptors (alpha, beta), Bcl-2 expression in human breast cancer and treatment response.
Telomerase activity, Ki-67, cyclin D1 and A expression, and apoptosis in solitary fibrous tumors: additional features of a predictable course?
Telomerase activity, MIB-1, PCNA, HPV 16 and p53 as diagnostic markers for cervical intraepithelial neoplasia.
Telomerase activity, Myc and Bcl-2: possible indicators of effective therapy of prostate cancer with 9-nitrocamptothecin.
Telomerase activity, P53 mutation and Ki-ras codon 12 point mutation of the peripheral blood in patients with hepato pancreato biliary diseases.
Telomerase activity, telomere length and human telomerase reverse transcriptase expression in hepatocellular carcinoma is independent of hepatitis virus status.
Telomerase activity, telomere length, and apoptosis: a comparison between acquired cholesteatoma and squamous cell carcinoma.
Telomerase activity, telomere length, and DNA ploidy in prostatic intraepithelial neoplasia (PIN).
Telomerase activity, TERT expression, hTERT promoter alterations, and alternative lengthening of the telomeres (ALT) in meningiomas - a systematic review.
Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression.
Telomerase activity: a biomarker of cell proliferation, not malignant transformation.
Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.
Telomerase activity: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase activity: comparison between fine-needle aspiration and biopsy specimens for the detection of tumor cells.
Telomerase and breast cancer.
Telomerase and breast cancer: from diagnosis to therapy.
Telomerase and c-myc expression in hepatocellular carcinomas.
Telomerase and cancer management: silver bullet or fool's gold?
Telomerase and cancer stem cells.
Telomerase and cancer therapeutics.
Telomerase and cancer.
Telomerase and cancer. The Fifth International Symposium of the Hiroshima Cancer Seminar October 1995, Hiroshima, Japan.
Telomerase and Cancer: Kirk A. Landon--AACR prize for basic cancer research lecture.
Telomerase and cancer: revisiting the telomere hypothesis.
Telomerase and cancer: time to move from a promising target to a clinical reality.
Telomerase and cancer: where and when?
Telomerase and CD4 T Cell Immunity in Cancer.
Telomerase and cell proliferation in mouse skin papillomas.
Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again.
Telomerase and drug resistance in cancer.
Telomerase and early detection of cancer: a National Cancer Institute workshop.
Telomerase and HER-2/neu as targets of genetic cancer vaccines in dogs.
Telomerase and human papillomavirus as diagnostic adjuncts for cervical dysplasia and carcinoma.
Telomerase and its potential for therapeutic intervention.
Telomerase and mammalian ageing: a critical appraisal.
Telomerase and markers of cellular proliferation are associated with the progression of cervical intraepithelial neoplasia lesions.
Telomerase and oral cancer.
Telomerase and other novel approaches to bladder cancer detection.
Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells.
Telomerase and poly(ADP-ribose) polymerase-1 activity sensing based on the high fluorescence selectivity and sensitivity of TOTO-1 towards G bases in single-stranded DNA and poly(ADP-ribose).
Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy.
Telomerase and Retrotransposons: Reverse Transcriptases That Shaped Genomes Special Feature Sackler Colloquium: Maintenance of tumor initiating cells of defined genetic composition by nucleostemin.
Telomerase and telomere biology in hematological diseases: A new therapeutic target.
Telomerase and telomere dynamics in ageing and cancer: current status and future directions.
Telomerase and telomere inhibitors in preclinical development.
Telomerase and Telomere Length in Pulmonary Fibrosis.
Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer.
Telomerase and telomere stability: a new class of tumor suppressor?
Telomerase and Telomeres Biology in Thyroid Cancer.
Telomerase and Telomeres in Endometrial Cancer.
Telomerase and telomeres: from basic biology to cancer treatment.
Telomerase and the aging process.
Telomerase and the benign and malignant megakaryoblastic leukemias of Down syndrome.
Telomerase and the endocrine system.
Telomerase and the search for the end of cancer.
Telomerase and tumorigenesis.
Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks.
Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
Telomerase antisense inhibition for the proliferation of endometrial cancer in vitro and in vivo.
Telomerase as a cancer target. Development of new molecules.
Telomerase as a clinical target: current strategies and potential applications.
Telomerase as a diagnostic and predictive marker in colorectal carcinoma.
Telomerase as a diagnostic and therapeutic target for cancer.
Telomerase as a marker for cancer.
Telomerase as a new target for pancreatic cancer treatment.
Telomerase as a new target for the treatment of hormone-refractory prostate cancer.
Telomerase as a novel and potentially selective target for cancer chemotherapy.
Telomerase as a possible target for anticancer therapy.
Telomerase as a potential anticancer target: growth inhibition and genomic instability.
Telomerase as a potential marker for inflammation and cancer detection in bronchial washing: A prospective study.
Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hTERT and hTR.
Telomerase as a promising target for human cancer gene therapy.
Telomerase as a target for cancer immunotherapy.
Telomerase as a target for cancer therapy.
Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential.
Telomerase as a therapeutic target for malignant gliomas.
Telomerase as a therapeutic target in glioblastoma.
Telomerase as a therapeutic target.
Telomerase as a tool for the differential diagnosis of human hepatocellular carcinoma.
Telomerase as a tumor marker in diagnosis of prostatic intraepithelial neoplasia and prostate cancer.
Telomerase as a tumor-associated antigen for cancer immunotherapy.
Telomerase as a universal tumor antigen for cancer vaccines.
Telomerase as a universal tumor-associated antigen for cancer immunotherapy.
Telomerase as a useful target in cancer fighting-the breast cancer case.
Telomerase as an anti-cancer drug target: will it fulfil its early promise?
Telomerase as an emerging target to fight cancer - Opportunities and challenges for nanomedicine.
Telomerase as an independent prognostic factor in head and neck squamous cell carcinoma.
Telomerase as drug and drug target for the treatment of thyroid cancer.
Telomerase as tumor marker.
Telomerase assay and HPV 16/18 typing as adjunct to conventional cytological cervical cancer screening.
Telomerase assay as a possible predictor of the response to anticancer chemotherapy.
Telomerase assay using biotinylated-primer extension and magnetic separation of the products.
Telomerase assays in the diagnosis and prognosis of cancer.
Telomerase at the intersection of cancer and aging.
Telomerase based anticancer immunotherapy and vaccines approaches.
Telomerase beyond telomeres.
Telomerase Biogenesis and Activities from the Perspective of Its Direct Interacting Partners.
Telomerase Biology Associations offer Keys to Cancer and Aging Therapeutics.
Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G1 cell cycle arrest in A549 cells.
Telomerase can't handle the stress.
Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study.
Telomerase components as a diagnostic tool in human oral lesions.
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism.
Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae.
Telomerase deficiency and cancer susceptibility syndromes.
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene.
Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.
Telomerase detection in body fluids.
Telomerase detection in the diagnosis and prognosis of cancer.
Telomerase detection using a DNA-PAINT strategy.
Telomerase directly regulates NF-?B-dependent transcription.
Telomerase downregulation in cancer brain stem cell.
Telomerase dysfunction and dyskeratosis congenita.
Telomerase Dysfunction in the Tumorigenesis of Genetic Disorders.
Telomerase efficiently elongates highly transcribing telomeres in human cancer cells.
Telomerase enzyme activation and human cell immortalization.
Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma.
Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells.
Telomerase enzyme activity as a diagnostic tool to distinguish effusions of malignant and benign origin.
Telomerase expression and cancer: a controversy finally put to rest?
Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors.
Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome.
Telomerase expression as a marker in prostate cancer: correlation to clinicopathologic predictors.
Telomerase Expression in a Series of Melanocytic Neoplasms.
Telomerase expression in benign and malignant skin neoplasms: comparison of three major subunits.
Telomerase expression in gliomas including the nonastrocytic tumors.
Telomerase expression in human breast cancer with and without lymph node metastases.
Telomerase expression in intracranial tumours: prognostic potential for malignant gliomas and meningiomas.
Telomerase expression in lung preneoplasia and neoplasia.
Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer.
Telomerase expression in normal endometrium, endometrial hyperplasia, and endometrial adenocarcinoma.
Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix.
Telomerase expression in primary neuroblastomas.
Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.
Telomerase expression in sebaceous carcinoma of the eyelid.
Telomerase expression in sebaceous lesions of the skin.
Telomerase expression in uveal melanoma.
Telomerase expression is differentially regulated in birds of differing life span.
Telomerase expression of malignant epithelial cells correlates with Dukes' stage in colorectal cancer.
Telomerase expression predicts unfavorable outcome in osteosarcoma.
Telomerase expression shows differences across multiple regions of oligodendroglioma versus high grade astrocytomas but shows correlation with Mib-1 labelling.
Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene.
Telomerase functions beyond telomere maintenance in primary cutaneous T-cell lymphoma.
Telomerase gene expression in intraductal papillary-mucinous tumors (IPMT): preliminary findings.
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.
Telomerase immunity from bench to bedside: round one.
Telomerase in (pre)neoplastic cervical disease.
Telomerase in anti-tumor response.
Telomerase in brain tumors.
Telomerase in breast cancer: a critical evaluation.
Telomerase in cancer and aging.
Telomerase in cancer diagnosis and therapy: a clinical perspective.
Telomerase in cancer immunotherapy.
Telomerase in cancer: clinical applications.
Telomerase in cancer: diagnostic, prognostic, and therapeutic implications.
Telomerase in cutaneous carcinogenesis.
Telomerase in endocrine and endocrine-dependent tumors.
Telomerase in gynecologic cancers.
Telomerase in hematologic malignancies.
Telomerase in human bladder cancer.
Telomerase in human development and cancer.
Telomerase in human tumors: molecular diagnosis and clinical significance.
Telomerase in intracranial meningiomas.
Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer.
Telomerase in relation to expression of p53, c-Myc and estrogen receptor in ovarian tumours.
Telomerase in T lymphocytes: use it and lose it?
Telomerase in the early detection of cancer.
Telomerase in urological malignancy.
Telomerase Induction in HPV Infection and Oncogenesis.
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells.
Telomerase inhibition alters telomere maintenance mechanisms in laryngeal squamous carcinoma cells.
Telomerase inhibition and cancer: might platinum based drugs have a future as anti-telomerase pharmacological approach?
Telomerase Inhibition and Human Telomeric G-Quadruplex DNA Stabilization by a ?-Carboline-Benzimidazole Derivative at Low Concentrations.
Telomerase inhibition and telomere erosion: a two-pronged strategy in cancer therapy.
Telomerase Inhibition and Telomere Targeting in Hematopoietic Cancer Cell Lines with Small Non-Nucleosidic Synthetic Compounds (BIBR1532).
Telomerase inhibition and the future management of head-and-neck cancer.
Telomerase Inhibition as a Novel Therapy for Pediatric Ependymoma.
Telomerase inhibition as an adjuvant anticancer therapy: it is more than just a waiting game.
Telomerase inhibition as cancer therapy.
Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cells.
Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells.
Telomerase inhibition by siRNA causes senescence and apoptosis in Barrett's adenocarcinoma cells: mechanism and therapeutic potential.
Telomerase inhibition by stable RNA interference impairs tumor growth and angiogenesis in glioblastoma xenografts.
Telomerase inhibition by sulfoquinovosyldiacylglycerol from edible purple laver (Porphyra yezoensis).
Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines.
Telomerase inhibition decreases esophageal squamous carcinoma cell migration and invasion.
Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells.
Telomerase inhibition impairs tumor growth in glioblastoma xenografts.
Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.
Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation.
Telomerase inhibition in cancer therapeutics: molecular-based approaches.
Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells.
Telomerase inhibition induces acute ATM-dependent growth arrest in human astrocytomas.
Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.
Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle-specific manner.
Telomerase inhibition regulates EMT mechanism in breast cancer stem cells.
Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia.
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.
Telomerase inhibition, oligonucleotides, and clinical trials.
Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT.
Telomerase Inhibition, Telomere Shortening, and Cellular Uptake of the Perylene Derivatives PM2 and PIPER in Prostate Cancer Cells.
Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins.
Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells.
Telomerase inhibition: the way ahead for cancer therapy in humans and dogs?
Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo.
Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells.
Telomerase inhibitors and 'T-oligo' as cancer therapeutics: contrasting molecular mechanisms of cytotoxicity.
Telomerase inhibitors as anticancer therapy.
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.
Telomerase inhibitors for the treatment of brain tumors and the potential of intranasal delivery.
Telomerase inhibitors for the treatment of cancer: the current perspective.
Telomerase Inhibitors from Natural Products and Their Anticancer Potential.
Telomerase inhibitors identified by a forward chemical genetics approach using a yeast strain with shortened telomere length.
Telomerase inhibitors in anticancer therapy: gossypol as a potential telomerase inhibitor.
Telomerase inhibitors in cancer therapy: current status and future directions.
Telomerase inhibitors.
Telomerase inhibitors: a new option for chemotherapy.
Telomerase inhibitors: a patent review (2010-2015).
Telomerase inhibitors: forcing the end to put an end.
Telomerase inhibitors: targeting the vulnerable end of cancer?
Telomerase inhibitory effects of medicinal mushrooms and lichens, and their anticancer activity.
Telomerase is a highly sensitive and specific molecular marker in fine-needle aspirates of breast lesions.
Telomerase is activated in the prostate and seminal vesicles of the castrated rat.
Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions.
Telomerase is controlled by protein kinase Calpha in human breast cancer cells.
Telomerase is frequently activated in tumors with microsatellite instability.
Telomerase is not activated in human hyperplastic and adenomatous parathyroid tissue.
Telomerase is not an epidermal stem cell marker and is downregulated by calcium.
Telomerase is not an oncogene.
Telomerase is not required for experimental tumorigenesis of human and bovine adrenocortical cells.
Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells.
Telomerase is regulated by protein kinase C-zeta in human nasopharyngeal cancer cells.
Telomerase is strongly activated in hepatocellular carcinoma but not in chronic hepatitis and cirrhosis.
Telomerase is upregulated in irreversible preneoplastic lesions during bladder carcinogenesis in rats.
Telomerase linked with cancer risk?
Telomerase lost?
Telomerase maintains telomere structure in normal human cells.
Telomerase Modulation in Therapeutic Approach.
Telomerase mRNA detection in serum of patients with prostate cancer.
Telomerase mRNA expression and immunohistochemical detection as a biomarker of malignant transformation in patients with inflammatory bowel disease.
Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer.
Telomerase Plays a Pivotal Role in Collateral Growth Under Ischemia by Suppressing Age-Induced Oxidative Stress, Expression of p53, and Pro-Apoptotic Proteins.
Telomerase promoter mutations and copy number alterations in solitary fibrous tumours.
Telomerase promoter mutations in cancer: an emerging molecular biomarker?
Telomerase promoter mutations in human immunodeficiency virus-related conjunctiva neoplasia.
Telomerase promoter-driven cancer gene therapy.
Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells.
Telomerase promotes formation of a telomere protective complex in cancer cells.
Telomerase pulsed dendritic cells for immunotherapy for renal cell carcinoma.
Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases.
Telomerase reactivation in cancers: Mechanisms that govern transcriptional activation of the wild-type vs. mutant TERT promoters.
Telomerase reactivation is associated with hepatobiliary and pancreatic cancers.
Telomerase recruitment requires both TCAB1 and Cajal bodies independently.
Telomerase recruitment to telomeres.
Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity.
Telomerase redux: ready for prime time?
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.
Telomerase regulation at the crossroads of cell fate.
Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells.
Telomerase regulation in hematological cancers: A matter of stemness?
Telomerase regulation: A key to inhibition? (Review).
Telomerase Regulation: A Role for Epigenetics.
Telomerase repeat amplification protocol (TRAP): A new molecular marker for parathyroid carcinoma.
Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells.
Telomerase Responsive Delivery of Doxorubicin from Mesoporous Silica Nanoparticles in Multiple Malignancies: Therapeutic Efficacies against Experimental Aggressive Murine Lymphoma.
Telomerase reverse transcriptase (hTERT) mRNA and telomerase RNA (hTR) as targets for downregulation of telomerase activity.
Telomerase reverse transcriptase (TERT) expression and role of vincristine sulfate in mouse model of malignancy related peritoneal ascites: an experimental metastatic condition.
Telomerase reverse transcriptase (TERT) expression in canine mammary tissues: a specific marker for malignancy?
Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With Felis catus Papillomavirus Type-2 Infection.
Telomerase reverse transcriptase (TERT) is a novel target of Wnt/?-catenin pathway in human cancer.
Telomerase reverse transcriptase (TERT) promoter mutations are rare in urachal cancer.
Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review.
Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activity.
Telomerase reverse transcriptase alterations in human cancers: Diagnosis, prognosis, and therapeutic implications.
Telomerase reverse transcriptase as target for anti-tumor T cell responses in humans.
Telomerase reverse transcriptase catalytic subunit expression and proliferation index in Wilms tumor.
Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members.
Telomerase reverse transcriptase delays aging in cancer-resistant mice.
Telomerase reverse transcriptase downregulation by RNA interference modulates endoplasmic reticulum stress and mitochondrial energy production.
Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas.
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence.
Telomerase reverse transcriptase expression protects transformed human cells against DNA-damaging agents, and increases tolerance to chromosomal instability.
Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma.
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.
Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: a genomic and molecular study.
Telomerase reverse transcriptase in the regulation of gene expression.
Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects.
Telomerase reverse transcriptase interference synergistically promotes tumor necrosis factor?related apoptosis?inducing ligand?induced oral squamous cell carcinoma apoptosis and suppresses proliferation in vitro and in vivo.
Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells.
Telomerase reverse transcriptase locus polymorphisms and cancer risk: a field synopsis and meta-analysis.
Telomerase reverse transcriptase mediates EMT through NF-?B signaling in tongue squamous cell carcinoma.
Telomerase reverse transcriptase methylation predicts lymph node metastasis and prognosis in patients with gastric cancer.
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase.
Telomerase reverse transcriptase mRNA expression and telomerase activity in hepatocellular carcinoma.
Telomerase Reverse Transcriptase Polymorphism rs2736100: A Balancing Act between Cancer and Non-Cancer Disease, a Meta-Analysis.
Telomerase reverse transcriptase potentially promotes the progression of oral squamous cell carcinoma through induction of epithelial-mesenchymal transition.
Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients.
Telomerase reverse transcriptase promoter mutations in cancers derived from multiple organ sites among middle eastern population.
Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma.
Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma.
Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia.
Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression.
Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells.
Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma.
Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy.
Telomerase reverse transcriptase subunit immunoreactivity: a marker for high-grade prostate carcinoma.
Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity.
Telomerase reverse transcriptase-dependent telomere equilibration mitigates tissue dysfunction in mTert heterozygotes.
Telomerase RNA accumulates in Cajal bodies in human cancer cells.
Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes.
Telomerase RNA biosynthesis and processing.
Telomerase RNA expression and DNA ploidy as prognostic markers of prostate carcinomas.
Telomerase RNA expression during progression of gastric cancer.
Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate.
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis.
Telomerase stability and evaluation of real-time telomeric repeat amplification protocol.
Telomerase still 'investigational' in its application to cancer management.
Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions.
Telomerase structure function.
Telomerase structure paves the way for new cancer therapies.
Telomerase structure.
Telomerase structures and regulation: shedding light on the chromosome end.
Telomerase subunit immunoreactivity and recurrence in colorectal cancer.
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles.
Telomerase suppression initiates PML-dependent p53 activation to inhibit bladder cancer cell growth.
Telomerase targeted oligonucleotide thio-phosphoramidates in T24-luc bladder cancer cells.
Telomerase targeted therapy in cancer and cancer stem cells.
Telomerase targeting in cancer treatment: new developments.
Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer.
Telomerase therapeutics for cancer: challenges and new directions.
Telomerase therapeutics for degenerative diseases.
Telomerase therapeutics: telomeres recognized as a DNA damage signal: commentary re: K. Kraemer et al., antisense-mediated hTERT inhibition specifically reduces the growth of human bladder cancer cells. Clin. Cancer Res., 9: 3794-3800, 2003.
Telomerase Triggered DNA Walker with a Superhairpin Structure for Human Telomerase Activity Sensing.
Telomerase Triggered Drug Release Using a SERS Traceable Nanocarrier.
Telomerase vaccination has no detectable effect on SCID-repopulating and colony-forming activities in the bone marrow of cancer patients.
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.
Telomerase, cell immortality, and cancer.
Telomerase, cervical cancer, and human papillomavirus.
Telomerase, checkpoints and cancer.
Telomerase, hTERT and splice variants in Barrett's oesophagus and oesophageal adenocarcinoma.
Telomerase, immortality and cancer.
Telomerase, immortality, and cancer.
Telomerase, p53 and human papillomavirus infection in the uterine cervix.
Telomerase, p53 and PCNA activity in osteosarcoma.
Telomerase, senescence and ageing.
Telomerase, telomerase inhibition, and cancer.
Telomerase- and alternative telomere lengthening-independent telomere stabilization in a metastasis-derived human non-small cell lung cancer cell line: effect of ectopic hTERT.
Telomerase--a potential molecular marker of lung and cervical cancer.
Telomerase-A molecular marker for cervical cancer screening.
Telomerase-based cancer therapeutics: a review on their clinical trials.
Telomerase-based immunotherapy of cancer.
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.
Telomerase-dependent gene therapy.
Telomerase-dependent oncolytic adenovirus for cancer treatment.
Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.
Telomerase-Driven Expression of the Sodium Iodide Symporter (NIS) for in Vivo Radioiodide Treatment of Cancer: A New Broad-Spectrum NIS-Mediated Antitumor Approach.
Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate.
Telomerase-immortalized sheep fibroblasts can be reprogrammed by nuclear transfer to undergo early development.
Telomerase-independent paths to immortality in predictable cancer subtypes.
Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer.
Telomerase-independent stabilization of short telomeres in Trypanosoma brucei.
Telomerase-Mediated Apoptosis of Chicken Lymphoblastoid Tumor Cell Line by Lanthanum Chloride.
Telomerase-pulsed dendritic cells: preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma.
Telomerase-specific attenuated viruses, a definitive strategy or just one more in circulating tumor cells detection anthology?
Telomerase-specific GV1001 peptide vaccination fails to induce objective tumor response in patients with cutaneous T cell lymphoma.
Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice.
Telomerase-specific oncolytic virotherapy for human cancer with the hTERT promoter.
Telomerase-specific oncolytic virotherapy for human gastrointestinal cancer.
Telomerase-specific replication-selective virotherapy for human cancer.
Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.
Telomerase-Specific T-Cell Immunity in Breast Cancer: Effect of Vaccination on Tumor Immunosurveillance.
Telomerase-specific virotherapy for human squamous cell carcinoma.
Telomerase-specific virotherapy in an animal model of human head and neck cancer.
Telomerase-Targeted Cancer Immunotherapy.
Telomerase-targeting antisense oligonucleotides carried by polycation liposomes enhance the growth inhibition effect on tumor cells.
Telomerase. A target for anticancer therapy.
Telomerase: a crucial player in HTLV-I-induced human T-cell leukemia.
Telomerase: A missing link between ageing, cancer and novel therapies?
Telomerase: a potential diagnostic and therapeutic tool in canine oncology.
Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase: a potential molecular marker and therapeutic target for cancer.
Telomerase: a potential therapeutic target for cancer.
Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review.
Telomerase: a target for cancer therapeutics.
Telomerase: A Target for Therapeutic Effects of Curcumin in Cancer.
Telomerase: a therapeutic target for the third millennium?
Telomerase: An exploration toward the end of cancer.
Telomerase: anti-cancer target or just a fascinating enzyme?
Telomerase: biological function and potential role in cancer management.
Telomerase: biology and phase I trials.
Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex.
Telomerase: central regulator of all of the hallmarks of cancer.
Telomerase: diagnostics, cancer therapeutics and tissue engineering.
Telomerase: going beyond the ends.
Telomerase: is it the future diagnostic and prognostic tool in human cancer?
Telomerase: Key regulator of inflammation and cancer.
Telomerase: optimism for cancer marker grows.
Telomerase: regulation, function and transformation.
Telomerase: structure, functions, and activity regulation.
Telomerase: The Devil Inside.
Telomerase: the search for a universal cancer vaccine.
Telomerase: therapeutic potential in cancer.
Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.
Telomere and telomerase as targets for anti-cancer and regeneration therapies.
Telomere and Telomerase as Targets for Cancer Therapy.
Telomere and telomerase dynamics in human cells.
Telomere and telomerase in oncology.
Telomere and telomerase stability in human diseases and cancer.
Telomere and Telomerase Therapeutics in Cancer.
Telomere attrition and telomerase activity are associated with GSTM1 polymorphism in oral cancer.
Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix.
Telomere biology and the molecular basis of aging.
Telomere biology in Metazoa.
Telomere biology of pediatric cancer.
Telomere biology: cancer firewall or aging clock?
Telomere DNA Damage Signaling Regulates Prostate Cancer Tumorigenesis.
Telomere dynamics and cytogenetic changes in human hematologic neoplasias: a working hypothesis.
Telomere dynamics and genome stability in the human pancreatic tumor cell line MIAPaCa-2.
Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells.
Telomere dynamics and telomerase activation in tumor progression: prospects for prognosis and therapy.
Telomere dynamics in cells with introduced telomerase: a rapid assay for telomerase activity on telomeres.
Telomere dynamics in childhood leukemia and solid tumors: a follow-up study.
Telomere dynamics in mice and humans.
Telomere dysfunction alters the chemotherapeutic profile of transformed cells.
Telomere dysfunction and chromosome instability.
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.
Telomere dysfunction and hematologic disorders.
Telomere dysfunction and telomerase activation in cancer--a pathological paradox?
Telomere dysfunction in aging and cancer.
Telomere dysfunction in human bone marrow failure syndromes.
Telomere dysfunction increases mutation rate and genomic instability.
Telomere dysfunction induced by chemotherapeutic agents and radiation in normal human cells.
Telomere Dysfunction Induced Foci (TIF) Analysis.
Telomere dysfunction is related to the intrinsic radio-resistance of human oral cancer cells.
Telomere dysfunction results in enhanced organismal sensitivity to the alkylating agent N-methyl-N-nitrosourea.
Telomere dysfunction suppresses multiple endocrine neoplasia in mice.
Telomere Dysfunction, Chromosomal Instability and Cancer.
Telomere elongation chooses TERRA ALTernatives.
Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood.
Telomere elongation-based DNA-Catalytic amplification strategy for sensitive SERS detection of telomerase activity.
Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6.
Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: implications for antitelomerase therapy.
Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells.
Telomere function in colorectal cancer.
Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation.
Telomere G-Quadruplex as a Potential Target to Accelerate Telomere Shortening by Expanding the Incomplete End-Replication of Telomere DNA.
Telomere Gene Therapy: Polarizing Therapeutic Goals for Treatment of Various Diseases.
Telomere higher-order structure and genomic instability.
Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein.
Telomere instability in papillary bladder urothelial carcinomas: Comparison with grading and risk of recurrence.
Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis.
Telomere Length and Hematological Disorders: A Review.
Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma.
Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species.
Telomere Length and Telomerase Activity Impact the UV Sensitivity Syndrome Xeroderma Pigmentosum C.
Telomere length and telomerase activity in bladder and prostate cancer cell lines.
Telomere length and telomerase activity in canine mammary gland tumors.
Telomere length and telomerase activity in carcinogenesis of the stomach.
Telomere length and telomerase activity in extra-abdominal desmoid tumors.
Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse.
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status.
Telomere length and telomerase activity in the context of menopause.
Telomere length and telomerase activity predict survival in patients with B cell chronic lymphocytic leukemia.
Telomere length and telomerase activity: variations with advancing age and potential role in childhood malignancies.
Telomere length and telomerase catalytic subunit expression in non-astrocytic gliomas.
Telomere length and telomerase expression in pituitary tumors.
Telomere length and TERT abnormalities in pituitary adenomas.
Telomere Length and the Cancer-Atherosclerosis Trade-Off.
Telomere length correlates with histopathogenesis according to the germinal center in mature B-cell lymphoproliferative disorders.
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice.
Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres.
Telomere length homeostasis requires that telomerase levels are limiting.
Telomere length in different histologic types of ovarian carcinoma with emphasis on clear cell carcinoma.
Telomere length in normal and neoplastic canine tissues.
Telomere Length in Peripheral Blood Lymphocytes Contributes to the Development of HPV-Associated Oropharyngeal Carcinoma.
Telomere length influences cancer cell differentiation in vivo.
Telomere length is a prognostic factor in neuroblastoma.
Telomere length is related to alternative splice patterns of telomerase in thyroid tumors.
Telomere length maintenance in aging and carcinogenesis.
Telomere Length Maintenance in Cancer: At the Crossroad between Telomerase and Alternative Lengthening of Telomeres (ALT).
Telomere length maintenance--an ALTernative mechanism.
Telomere length of cord blood-derived CD34(+) progenitors predicts erythroid proliferative potential.
Telomere length of tumor tissues and survival in patients with early stage non-small cell lung cancer.
Telomere length regulation.
Telomere length, telomerase activity and telomerase RNA expression during mouse mammary tumor progression.
Telomere lengthening early in development.
Telomere lengthening in telomerase-negative cells: the ends are coming together.
Telomere lengths and telomerase activity in dog tissues: a potential model system to study human telomere and telomerase biology.
Telomere loss as a mechanism for chromosome instability in human cancer.
Telomere loss: mitotic clock or genetic time bomb?
Telomere maintenance and cancer -- look, no telomerase.
Telomere maintenance and disease.
Telomere maintenance and tumorigenesis: an "ALT"ernative road.
Telomere maintenance as a target for anticancer drug discovery.
Telomere Maintenance as a Target for Drug Discovery.
Telomere maintenance as therapeutic target in embryonal tumours.
Telomere maintenance by recombination in human cells.
Telomere maintenance in childhood primitive neuroectodermal brain tumors.
Telomere maintenance in clinical medicine.
Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer.
Telomere maintenance in laser capture microdissection-purified Barrett's adenocarcinoma cells and effect of telomerase inhibition in vivo.
Telomere Maintenance in Pediatric Cancer.
Telomere maintenance in sarcomas.
Telomere maintenance in wilms tumors: First evidence for the presence of alternative lengthening of telomeres mechanism.
Telomere maintenance mechanisms as a target for drug development.
Telomere Maintenance Mechanisms in Cancer.
Telomere maintenance mechanisms in cancer: telomerase, ALT or lack thereof.
Telomere maintenance mechanisms in liposarcomas: association with histologic subtypes and disease progression.
Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance.
Telomere profiles and tumor-associated macrophages with different immune signatures affect prognosis in glioblastoma.
Telomere profiling: toward glioblastoma personalized medicine.
Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage.
Telomere protein complexes and their role in lymphoid malignancies.
Telomere recombination and alternative telomere lengthening mechanisms.
Telomere Recombination and the ALT Pathway: a Therapeutic Perspective for Cancer.
Telomere reduction in human colorectal carcinoma and with ageing.
Telomere regulation during ageing and tumorigenesis of the grey mouse lemur.
Telomere repeat amplification protocol (TRAP) in situ reveals telomerase activity in three cell types in effusions: malignant cells, proliferative mesothelial cells, and lymphocytes.
Telomere Restriction Fragment (TRF) Analysis.
Telomere Reverse Transcriptase (TERT) rs2735940 Increases Cancer Risk.
Telomere sequence content can be used to determine ALT activity in tumours.
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells.
Telomere shortening and cell fates in mouse models of neoplasia.
Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells.
Telomere shortening and expression of TRF1 and TRF2 in uterine leiomyoma.
Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991.
Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas.
Telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesions.
Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas.
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
Telomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine.
Telomere shortening in gastric carcinoma with aging despite telomerase activation.
Telomere shortening in human HL60 cells by treatment with 3'-azido-2',3'-dideoxynucleosides and telomerase inhibition by their 5'-triphosphates.
Telomere shortening in mucosa surrounding the tumor: biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell carcinoma.
Telomere shortening is associated with poor prognosis and telomerase activity correlates with DNA repair impairment in non-small cell lung cancer.
Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafish.
Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms.
Telomere stability and carcinogenesis: an off-again, on-again relationship.
Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity.
Telomere structure and telomerase expression during mouse development and tumorigenesis.
Telomere structure and telomerase in health and disease (Review).
Telomere Terminal G/C Strand Synthesis: Measuring Telomerase Action and C-Rich Fill-In.
Telomere Transcripts Target Telomerase in Human Cancer Cells.
Telomere, telomerase and digestive cancer.
Telomere, telomerase, tumorigenesis and therapy: an overview.
Telomere-associated genes and telomeric lncRNAs are biomarker candidates in lung squamous cell carcinoma (LUSC).
Telomere-based cancer treatment: emerging targeted therapies.
Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression.
Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells.
Telomere-driven genomic instability in cancer cells.
Telomere-interactive agents affect proliferation rates and induce chromosomal destabilization in sea urchin embryos.
Telomere-maintenance mechanisms in soft-tissue malignant fibrous histiocytomas.
Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice.
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae.
Telomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: Pathogenic and clinical implications.
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data.
Telomeres and cancer: a tale with many endings.
Telomeres and cancer: from crisis to stability to crisis to stability.
Telomeres and disease.
Telomeres and human disease: ageing, cancer and beyond.
Telomeres and telomerase as targets for cancer therapy.
Telomeres and telomerase biology in vertebrates: progress towards a non-human model for replicative senescence and ageing.
Telomeres and telomerase in adrenocortical tissue maintenance, carcinogenesis and aging.
Telomeres and telomerase in ageing and cancer.
Telomeres and telomerase in aging and cancer.
Telomeres and telomerase in aging, regeneration and cancer.
Telomeres and telomerase in cancer stem cells.
Telomeres and telomerase in cancer.
Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy.
Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma.
Telomeres and telomerase in endocrine pathology.
Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.
Telomeres and telomerase in hematologic neoplasia.
Telomeres and Telomerase in Hematopoietic Dysfunction: Prognostic Implications and Pharmacological Interventions.
Telomeres and telomerase in human cancer (review).
Telomeres and telomerase in human health and disease.
Telomeres and telomerase in human hematologic neoplasia.
Telomeres and telomerase in human leukemias.
Telomeres and telomerase in lung cancer.
Telomeres and telomerase in normal and cancer stem cells.
Telomeres and telomerase in normal and malignant haematologic cells.
Telomeres and telomerase in oncogenesis.
Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology.
Telomeres and telomerase in sarcomas.
Telomeres and telomerase in T cells of tumor immunity.
Telomeres and telomerase in the clinical management of colorectal cancer.
Telomeres and Telomerase in the Development of Liver Cancer.
Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.
Telomeres and telomerase. A survey about methods and recent advances in cancer diagnostic and therapy.
Telomeres and telomerase: a dual role in hepatocarcinogenesis.
Telomeres and telomerase: basic science implications for aging.
Telomeres and telomerase: Biological and clinical importance in dogs.
Telomeres and telomerase: biological and clinical importance.
Telomeres and telomerase: from discovery to clinical trials.
Telomeres and telomerase: implications for cancer and aging.
Telomeres and telomerase: pharmacological targets for new anticancer strategies?
Telomeres and Telomerase: Role in Marek's Disease Virus Pathogenesis, Integration and Tumorigenesis.
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.
Telomeres and telomerase: understanding basic structure and potential new therapeutic strategies targeting it in the treatment of cancer.
Telomeres and telomere dynamics: relevance to cancers of the GI tract.
Telomeres and thyroid cancer.
Telomeres as targets for anticancer therapies.
Telomeres in aging and disease: lessons from zebrafish.
Telomeres in cancer and ageing.
Telomeres in cancer and aging: lessons from the mouse.
Telomeres rather than telomerase a key target for anti-cancer therapy?
Telomeres, p53, HNF4?, and Liver Disease.
Telomeres, Reproductive Aging, and Genomic Instability During Early Development.
Telomeres, senescence, and hematopoietic stem cells.
Telomeres, telomerase and cancer.
Telomeres, telomerase and cancer: an endless search to target the ends.
Telomeres, telomerase and cancer: an up-date.
Telomeres, telomerase and cancer: is the magic bullet real?
Telomeres, telomerase and chromosome stability.
Telomeres, telomerase and colorectal cancer.
Telomeres, Telomerase and Leukaemia.
Telomeres, telomerase and oral cancer (Review).
Telomeres, telomerase and the cancer cell: an introduction.
Telomeres, telomerase, and apoptosis.
Telomeres, telomerase, and cancer.
Telomeres, telomerase, and cancer: life on the edge of genomic stability.
Telomeres, telomerase, and immortality.
Telomeres, telomerase, and myc. An update.
Telomeres, telomerase, and telomerase inhibition: clinical implications for cancer.
Telomeres, telomerase, and tumorigenesis--a review.
Telomeres-structure, function, and regulation.
Telomeres: Implications for Cancer Development.
Telomeres: stem cells, cancer and telomerase linked by WNT.
Telomeres: Stem cells, cancer and telomerase linked by WNT.
Telomeres: unlocking the mystery of cell division and aging.
Telomeric DNA: marker for human prostate cancer development?
Telomeric instability and reduced proliferative potential in ovarian surface epithelial cells from women with a family history of ovarian cancer.
Telomeric length in individuals and cell lines with altered p53 status.
Telomeric lengths and telomerase activity in liposarcomas.
Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition.
Telomeric recombination induced by dysfunctional telomeres.
Telomeric repeat amplification protocol: measuring the activity of the telomerase.
Telomeric Repeat Containing RNA (TERRA): Aging and Cancer.
Telomeric repeat-containing RNA and telomerase in human fetal oocytes.
Telomestatin: formal total synthesis and cation-mediated interaction of its seco-derivatives with G-quadruplexes.
TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers.
TERRA mimicking ssRNAs prevail over the DNA substrate for telomerase in vitro due to interactions with the alternative binding site.
TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours.
TERT biology and function in cancer: beyond immortalisation.
TERT C228T mutation in non-malignant bladder urothelium is associated with intravesical recurrence for patients with non-muscle invasive bladder cancer.
TERT Expression in Pituitary Adenomas.
TERT Gene rs2736100 and rs2736098 Polymorphisms are Associated with Increased Cancer Risk: A Meta-Analysis.
TERT gene: its function and dysregulation in cancer.
TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas.
TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti-CTLA4 treatment.
TERT polymorphisms rs2853669 and rs7726159 influence on prostate cancer risk in Russian population.
TERT promoter alterations could provide a solution for Peto's paradox in rodents.
TERT Promoter Alterations in Glioblastoma: A Systematic Review.
TERT promoter hot spot mutations are frequent in Indian cervical and oral squamous cell carcinomas.
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker.
TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma.
TERT promoter methylation and protein expression as predictive biomarkers for recurrence risk in patients with serous borderline ovarian tumours.
TERT promoter methylation is significantly associated with TERT upregulation and disease progression in pituitary adenomas.
TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA.
TERT Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients.
TERT promoter mutation in adult granulosa cell tumor of the ovary.
TERT Promoter Mutation in an Aggressive Cribriform Morular Variant of Papillary Thyroid Carcinoma.
TERT promoter mutation in resectable hepatocellular carcinomas: a strong association with hepatitis C infection and absence of hepatitis B infection.
TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.
TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up.
TERT promoter mutation subtypes and survival in stage I and II melanoma patients.
TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors.
TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends.
TERT promoter mutations and gene amplification: promoting TERT expression in Merkel cell carcinoma.
TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas.
TERT promoter mutations and monoallelic activation of TERT in cancer.
TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma.
TERT promoter mutations and prognosis in solitary fibrous tumor.
TERT promoter mutations and telomeres during tumorigenesis.
TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer.
TERT promoter mutations and their correlation with BRAF and RAS mutations in a consecutive cohort of 145 thyroid cancer cases.
TERT Promoter Mutations and Their Impact on Gene Expression Profile in Papillary Thyroid Carcinoma.
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas.
TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.
TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas.
TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma.
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.
TERT promoter mutations are rare in bone and soft tissue sarcomas of Japanese patients.
TERT promoter mutations contribute to subset prognostication of lower-grade gliomas.
TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions.
TERT promoter mutations in cancer development.
TERT promoter mutations in clear cell renal cell carcinoma.
TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation.
TERT promoter mutations in penile squamous cell carcinoma: high frequency in non-HPV-related type and association with favorable clinicopathologic features.
TERT promoter mutations in primary and secondary glioblastomas.
TERT Promoter Mutations in Skin Cancer: the Effects of Sun Exposure and X-Irradiation.
TERT promoter mutations in telomere biology.
TERT Promoter Mutations in Thyroid Cancer.
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
TERT Promoter Mutations Reactivate Telomerase in Urothelial Carcinoma.
TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas.
TERT promotes cellular and organismal survival independently of telomerase activity.
TERT rs10069690 polymorphism and cancers risk: A meta-analysis.
TERT rs2736100 genotypes are associated with differential risk of myeloproliferative neoplasms in Swedish and Chinese male patient populations.
TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability.
TERT, a promoter of CNS malignancies.
TERT-Regulation and Roles in Cancer Formation.
Tes, a potential Mena-related cancer therapy target.
Tetracationic porphyrins inhibit angiogenesis induced by human tumor cells in vivo.
Tetraplex binding molecules as anti-cancer agents.
TGF beta1 induces multiple independent signals to regulate human trophoblastic differentiation: mechanistic insights.
TGF-?-mediated regulation of plasminogen activators is human telomerase reverse transcriptase dependent in cancer cells.
TGF-beta and cancer: Is Smad3 a repressor of hTERT gene?
The 'other' telomerase inhibitors: non-G-quadruplex interactive agent, non-antisense, non-reverse transcriptase telomerase inhibitors.
The 5'-end of hTERT mRNA is a good target for hammerhead ribozyme to suppress telomerase activity.
The ?-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype.
The AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assembly.
The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors.
The activity of human telomerase in the cells of acute leukaemias.
The addition of a spin column step in the telomeric repeat application protocol removes telomerase inhibitors.
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas.
The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression.
The anti-fibrotic effect of GV1001 combined with gemcitabine on treatment of pancreatic ductal adenocarcinoma.
The Anticancer Efficacy of Platinum Azidothymidin on Hepatocellular Carcinoma Via Affecting the Telomerase and the BcL-2 Genes Expression.
The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells.
The association between telomerase activity and expression of its RNA component (hTR) in breast cancer patients: the importance of DNase treatment.
The association between telomerase activity and hormone receptor status and p53 expression in breast cancer.
The association between telomerase, histopathological parameters, and KI-67 expression in breast cancer.
The association between telomerase, p53, and clinical staging in colorectal cancer.
The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population.
The Association of Aging-Related Polymorphisms with Susceptibility to Lung Cancer: A Case-Control Study in a Japanese Population.
The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America.
The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA.
The canine telomerase catalytic subunit (dogTERT): characterisation of the gene promoter and identification of proximal core sequences necessary for specific transcriptional activity in canine telomerase positive cell lines.
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.
The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis.
The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo.
The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.
The challenge of pathway and environment-mediated drug resistance.
The choice of the antigen in the dendritic cell-based vaccine therapy for prostate cancer.
The clinical implications of telomerase activity in upper tract urothelial cancer and washings.
The clinical significance of PINX1 expression in papillary thyroid carcinoma.
The clinical use of biomarkers as prognostic factors in Ewing sarcoma.
The Combination of TRAIL Treatment and Cancer Cell Selective Expression of TRAIL-Death Receptor DR4 Induces Cell Death in TRAIL-Resistant Cancer Cells.
The correlation between telomerase activity and Bax/Bcl-2 ratio in valproic acid-treated MCF-7 breast cancer cell line.
The current role of telomerase in the diagnosis of bladder cancer.
The design of G-quadruplex ligands as telomerase inhibitors.
The detection of minimal numbers of contaminating epithelial tumor cells in blood or bone marrow: use, limitations and future of RNA-based methods.
The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration.
The development of telomerase inhibitors: the G-quartet approach.
The difference between p53 mutation frequency in haematological and non-haematological malignancies: possible explanations.
The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.
The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase.
The disparity between human cell senescence in vitro and lifelong replication in vivo.
The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression.
The E6AP ubiquitin ligase is required for transactivation of the hTERT promoter by the human papillomavirus E6 oncoprotein.
The effect of Bortezomib and Rapamycin on Telomerase Activity in Mantle Cell Lymphoma.
The effect of raloxifene on telomerase expression in breast carcinoma samples from postmenopausal women.
The effect of silymarin on telomerase activity in the human leukemia cell line K562.
The Effect of Telomerase Template Antagonist GRN163L on Bone-Marrow-Derived Rat Mesenchymal Stem Cells is Reversible and Associated with Altered Expression of Cyclin d1, cdk4 and cdk6.
The Effect of Temperature on the Interaction of Phenanthroline-based Ligands with G-quadruplex: In Silico Viewpoint.
The Effect of Ubiquitin on Immune Response After Controlled Cortical Impact Injury.
The effects of erythropoietin signaling on telomerase regulation in non-erythroid malignant and non-malignant cells.
The Effects of Proteasome Inhibitors on Telomerase Activity and Regulation in Multiple Myeloma Cells.
The effects of telomerase inhibition on prostate tumor-initiating cells.
The effects of telomerase inhibitors on lymphocyte function.
The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis.
The efficacy of combination therapy using adeno-associated virus-TRAIL targeting to telomerase activity and cisplatin in a mice model of hepatocellular carcinoma.
The Emerging Roles for Telomerase in the Central Nervous System.
The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of TERT Promoter Mutations.
The evidences of human orphan receptor COUP-TFII inhibiting telomerase activity through decreasing hTERT transcription.
The evolving role of one-step nucleic acid amplification (OSNA) for the intra-operative detection of lymph node metastases: A diagnostic accuracy meta-analysis.
The evolving role of telomerase inhibitors in the treatment of cancer.
The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype.
The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinico-pathological parameters and clinical outcome.
The expression of hTERT mRNA and cellular immunity in gastric cancer and precancerosis.
The expression of messenger RNA for tumor necrosis factor-?; interleukins 1?, 6, 8, and 10; tissue growth factor-?; and interferon-? in bronchoalveolar lavage fluid cells from horses challenged with lipopolysaccharide and treated with clenbuterol
The expression of telomeric proteins and their probable regulation of telomerase during the differentiation of all-trans-retinoic acid-responsive and -resistant acute promyelocytic leukemia cells.
The Expression of the Phosphatase Regenerating Liver 3 Gene is Associated with Outcome in Patients with Colorectal Cancer.
The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance.
The first molecular details of ALT in human tumor cells.
The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
The G-quadruplex ligand, SYUIQ-FM05, targets proto-oncogene c-kit transcription and induces apoptosis in K562 cells.
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: the role of telomerase reactivation.
The higher incidence of squamous cell carcinoma in renal transplant recipients is associated with increased telomere lengths.
The HIV reverse transcriptase inhibitor tenofovir induces cell cycle arrest in human cancer cells.
The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor.
The hTERT and hTERC telomerase gene promoters are activated by the second exon of the adenoviral protein, E1A, identifying the transcriptional corepressor CtBP as a potential repressor of both genes.
The hTERT mRNA in plasma samples of early breast cancer patients, non-cancer patients and healthy individuals.
The hTERT protein as a marker for malignancy in meningiomas.
The human and canine TERT promoters function equivalently in human and canine cells.
The human CST complex is a terminator of telomerase activity.
The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells.
The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions.
The human telomere and its relationship to human disease, therapy, and tissue engineering.
The illusion of cell immortality.
The immunogenicity of the hTERT540-548 peptide in cancer.
The implication of telomerase activity and telomere stability for replicative aging and cellular immortality (Review).
The importance of the telomere and telomerase system in hematological malignancies.
The influence of reactivation of the telomerase in tumour tissue on the prognosis of squamous cell carcinomas in the head and neck.
The inhibitory effect of Gleditsia sinensis on cyclooxygenase-2 expression in human esophageal squamous cell carcinoma.
The inhibitory effect of helenalin on telomerase activity is attributed to the alkylation of the CYS445 residue: evidence from QM/MM simulations.
The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.
The interaction of telomere DNA G-quadruplex with three bis-benzyltetrahydroisoquinoline alkaloids.
The interactions of phenanthroline compounds with DNAs: Preferential binding to telomeric quadruplex over duplex.
The intragraft cytokine mRNA pattern reflects the efficacy of steroid antirejection therapy.
The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells.
The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo.
The landscape of fusion transcripts in spitzoid melanoma and biologically indeterminate spitzoid tumors by RNA sequencing.
The level of activity of the alternative lengthening of telomeres correlates with patient age in IDH-mutant ATRX-loss-of-expression anaplastic astrocytomas.
The level of telomere dysfunction determines the efficacy of telomerase-based therapeutics in a lung cancer cell line.
The levels of telomere-binding proteins in human tumours and therapeutic implications.
The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cells.
The makings of TERRA R-loops at chromosome ends.
The manipulation of chromosomes by mankind: the uses of microcell-mediated chromosome transfer.
The many faces of telomerase: emerging extratelomeric effects.
The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells.
The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis.
The molecular detection of circulating tumor cells in bladder cancer using telomerase activity.
The mouse skin carcinogenesis model.
The moving parts of the nucleolus.
The murine telomerase catalytic subunit shares the PAb-240 mutant specific epitope of the p53 protein.
The MUS81 endonuclease is essential for telomerase negative cell proliferation.
The mysteries of telomere structure and recognition: could radioprobing help?
The non-canonical functions of telomerase: to turn off or not to turn off.
The non-reverse transcriptase activity of the human telomerase reverse transcriptase promotes tumor progression (review).
The Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells.
The nuclear pore complex prevents sister chromatid recombination during replicative senescence.
The Over-Expression of E2F3 Might Serve as Prognostic Marker for Neuroblastoma Patients with Stage 4S Disease.
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor.
The Pinx1 Gene Downregulates Telomerase and Inhibits Proliferation of CD133+ Cancer Stem Cells Isolated from a Nasopharyngeal Carcinoma Cell Line by Regulating Trfs and Mad1/C-Myc/p53 Pathways.
The Polymorfisms of DNA G-Quadruplex investigated by Docking Experiments with Telomestatin Enantiomers.
The potential utility of telomere-related markers for cancer diagnosis.
The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients.
The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.
The prognostic significance of hTERT overexpression in cancers: A systematic review and meta-analysis.
The prognostic significance of TERT promoter mutations in meningioma: a systematic review and meta-analysis.
The prognostic value of hTERT expression levels in advanced-stage colorectal cancer patients: a comparison between tissue and serum expression.
The prognostic value of telomerase expression in peripheral blood mononuclear cells of head and neck cancer patients.
The promise of telomere length, telomerase activity and its regulation in the translocation-dependent cancer ESFT; clinical challenges and utility.
The Promoter of Human Telomerase Reverse Transcriptase is Activated during Liver Regeneration and Hepatocyte Proliferation.
The protective effects of Acanthus ilicifolius alkaloid A and its derivatives on pro- and anti-inflammatory cytokines in rats with hepatic fibrosis.
The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels.
The reactivation of telomerase activity in cancer progression.
The region upstream of the telomerase reverse transcriptase gene is essential for in planta telomerase complementation.
The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma.
The relationship between ligand aggregation and G-quadruplex DNA selectivity in a series of 3,4,9,10-perylenetetracarboxylic acid diimides.
The relationship between telomerase activity and proliferation in cutaneous melanoma.
The relationship between telomere length and telomerase activity in gynecologic cancers.
The relevance of RNA-directed DNA polymerase activity to human neoplasia.
The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis.
The RNA component of human telomerase.
The RNA component of telomerase as a marker of biologic potential and clinical outcome in childhood neuroblastic tumors.
The Role of Alternative Lengthening of Telomeres Mechanism in Cancer: Translational and Therapeutic Implications.
The Role of Alternative RNA Splicing in the Regulation of hTERT, Telomerase, and Telomeres: Implications for Cancer Therapeutics.
The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype.
The Role of Breast Cancer Stem Cells and Some Related Molecular Biomarkers in Metastatic and Nonmetastatic Breast Cancer.
The role of gene expression profiling in early-stage non-small cell lung cancer.
The role of HPV oncoproteins and cellular factors in maintenance of hTERT expression in cervical carcinoma cells.
The role of human cervical cancer oncogene in cancer progression.
The role of interferon-gamma and vitamin-A in modulating telomerase activity in breast cancer patients.
The role of microRNA-150 as a tumor suppressor in malignant lymphoma.
The role of recombination in telomere length maintenance.
The role of telomerase activation in the regulation of vascular smooth muscle cell proliferation.
The role of telomerase and viruses interaction in cancer development, and telomerase-dependent therapeutic approaches.
The Role of Telomere Biology in Cancer.
The role of telomeres and telomerase complex in haematological neoplasia: the length of telomeres as a marker of carcinogenesis and prognosis of disease.
The role of telomeres and telomerase in cancer research.
The role of telomeres and telomerase in cancer.
The role of telomeres and telomerase in endocrine tumors.
The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation.
The role of telomeres and telomerase in human cancer.
The role of telomeres and telomerase in stem cell aging.
The role of telomeres and telomerase in the pathology of human cancer and aging.
The role of telomeres in ageing and cancer.
The role of telomeres in the ageing of human skin.
The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma.
The Roles of Telomerase in the Generation of Polyploidy during Neoplastic Cell Growth.
The roles of telomeres and telomerase in cell life span.
The roles of telomeres and telomerase in cellular immortalization and the development of cancer.
The secrets of telomerase: Retrospective analysis and future prospects.
The sensitization of glioma cells to cisplatin and tamoxifen by the use of catechin.
The significance of human telomerase reverse transcriptase (hTERT) in cancer.
The significance of telomerase activation and cellular immortalization in human cancer.
The significance of telomerase activity in cancer lesions and the noncancerous epithelium of the esophagus.
The significant diagnostic value of human telomerase RNA component (hTERC) gene detection in high-grade cervical lesions and invasive cancer.
The significant role of telomerase activity in human brain tumors.
The Small Molecule BIBR1532 Exerts Potential Anti-cancer Activities in Preclinical Models of Feline Oral Squamous Cell Carcinoma Through Inhibition of Telomerase Activity and Down-Regulation of TERT.
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins.
The snoRNA domain of vertebrate telomerase RNA functions to localize the RNA within the nucleus.
The Solo Play of TERT Promoter Mutations.
The spontaneous regression of neoplasms in mammals: possible mechanisms and their application in immunotherapy.
The status of telomerase enzyme activity in benign and malignant gynaecologic pathologies.
The structures of quadruplex nucleic acids and their drug complexes.
The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence.
The telomerase activity and expression of hTERT gene can serve as indicators in the anti-cancer treatment of human ovarian cancer.
The Telomerase and Alternative Lengthening of Telomeres Mechanisms Regulate Laryngeal Cancer Cell Apoptosis via the PI3K/Akt Pathway.
The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.
The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes.
The telomerase challenge - an unusual problem in drug discovery.
The telomerase cycle: normal and pathological aspects.
The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2(+) breast cancer cells.
The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.
The telomerase inhibitor MST-312 synergistically enhances the apoptotic effect of doxorubicin in pre-B acute lymphoblastic leukemia cells.
The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.
The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters.
The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel.
The Telomerase-Derived Anticancer Peptide Vaccine GV1001 as an Extracellular Heat Shock Protein-Mediated Cell-Penetrating Peptide.
The telomere length dynamic and methods of its assessment.
The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas.
The telomere proteins in tumorigenesis and clinical outcomes of oral squamous cell carcinoma.
The telomere-associated homeobox-containing protein TAH1/HMBOX1 participates in telomere maintenance in ALT cells.
The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect?
The telomeric PARP, tankyrases, as targets for cancer therapy.
The TERT copy number gain is sensitive to telomerase inhibitors in human melanoma.
The TERT MNS16A polymorphism contributes to cancer susceptibility: Meta-analysis of the current studies.
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma.
The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer.
The TERT rs2736100 polymorphism increases cancer risk: A meta-analysis.
The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation.
The Truncated Human Telomeric Sequence forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K(+) Solution.
The tumor cell and telomerase.
The unmasking of telomerase.
The use of molecular profiling of early colorectal cancer to predict micrometastases.
The use of telomerase activity for the detection of prostatic cancer cells after prostatic massage.
The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage response.
The way to the end matters--the role of telomerase in tumor progression.
The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene.
Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase 1/2 trial.
Therapeutic efficacy of an hTERT promoter-driven oncolytic adenovirus that expresses apoptin in gastric carcinoma.
Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage.
Therapeutic strategies for targeting telomerase in cancer.
Therapeutic targeting of FOS in mutant TERT cancers through removing TERT suppression of apoptosis via regulating survivin and TRAIL-R2.
Therapeutic targeting of replicative immortality.
Therapeutic Targeting of Telomerase.
Therapeutic Targets in Telomerase and Telomere Biology of Cancers.
Therapeutic targets of cancer drugs: Modulation by melatonin.
Thermodynamic stability and statistical significance of potential stem-loop structures situated at the frameshift sites of retroviruses.
This month in investigative urology. Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer.
Thymidylate Synthase, Dihydropyrimidine Dehydrogenase, Thymidine Phosphorylase, Orotate Phosphoribosyltransferase mRNA Expression in Lung Cancer Metastatic Lymph Node Samples Obtained by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration - A Pilot Study.
Thymoquinone: An edible redox-active quinone for the pharmacotherapy of neurodegenerative conditions and glial brain tumors. A short review.
Thyroglobulin may affect telomerase activity in thyroid follicular cells.
Thyroid carcinomas that express telomerase follow a more aggressive clinical course in children and adolescents.
Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology.
Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA.
Titration of Variant HSV1-tk Gene Expression to Determine the Sensitivity of 18F-FHBG PET Imaging in a Prostate Tumor.
TNFalpha induces rapid activation and nuclear translocation of telomerase in human lymphocytes.
TnT: T antigen and telomerase, an explosive route to cancer.
TOA02, a Recombinant Adenovirus with Tumor-specific GM-CSF Expression, has Limited Biodistribution and Low Toxicity in Rhesus Monkeys.
Topoisomerase II alpha and telomerase expression in papillary thyroid carcinomas.
Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers.
Topological polar surface area: a useful descriptor in 2D-QSAR.
Total synthesis of the dictyodendrins as an arena to highlight emerging synthetic technologies.
Toward In Vitro Epigenetic Drug Design for Thyroid Cancer: The Promise of PF-03814735, an Aurora Kinase Inhibitor.
Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data.
TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends.
TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells.
Tracking viable circulating tumor cells (CTCs) in the peripheral blood of non-small cell lung cancer (NSCLC) patients undergoing definitive radiation therapy: pilot study results.
Training Performed Above Lactate Threshold Decreases p53 and Shelterin Expression in Mice.
Transcript regulation of human telomerase reverse transcriptase by c-myc and mad1.
Transcription and alternative splicing of telomerase reverse transcriptase in benign and malignant breast tumours and in adjacent mammary glandular tissues: implications for telomerase activity.
Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene.
Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family.
Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC.
Transcriptional regulation of telomeric non-coding RNA: Implications on telomere biology, replicative senescence and cancer.
Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms.
Transcriptional repression of telomerase RNA gene expression by c-Jun-NH2-kinase and Sp1/Sp3.
Transcriptional upregulation of DNA polymerase beta by TEIF.
Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line.
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene.
Transforming growth factor-beta inhibits telomerase through SMAD3 and E2F transcription factors.
Transgene expression of alpha tumor necrosis factor with mutations D142N and A144R under control of human telomerase reverse transcriptase promoter eradicates well-established tumors and induces long-term antitumor immunity.
Transient activation of the ALT pathway in human primary fibroblasts exposed to high-LET radiation.
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts.
Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination.
Transient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle Kinetics.
Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.
TRAP-LIG, a modified telomere repeat amplification protocol assay to quantitate telomerase inhibition by small molecules.
TRAP-silver staining, a highly sensitive assay for measuring telomerase activity in tumor tissue and cell lines.
Treating Cancer by Targeting Telomeres and Telomerase.
Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus.
Trend of telomerase activity change during human iPSC self-renewal and differentiation revealed by a quartz crystal microbalance based assay.
TRF2 inhibition promotes anchorage-independent growth of telomerase-positive human fibroblasts.
Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands.
Triethylenetetramine pharmacology and its clinical applications.
Triptolide inhibits transcription of hTERT through down-regulation of transcription factor specificity protein 1 in primary effusion lymphoma cells.
Triptolide inhibits tumor growth by induction of cellular senescence.
Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.
Troglitazone suppresses telomerase activity independently of PPARgamma in estrogen-receptor negative breast cancer cells.
Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase.
Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells.
Tumor cells fail to trans-induce telomerase in human umbilical vein endothelial cell cultures.
Tumor interstitial fluid and gastric cancer metastasis: an experimental study to verify the hypothesis of "tumor-phlegm microenvironment".
Tumor size-independence of telomere length indicates an aggressive feature of HCC.
Tumor specific cytotoxicity and telomerase down-regulation in prostate cancer by autologous dendritic cells loaded with whole tumor cell antigens.
Tumor suppressors p53, p63TA?, p63TAy, p73?, and p73? use distinct pathways to repress telomerase expression.
Tumor targeted radionuclide imaging and therapy using human sodium iodide symporter gene driven by a modified telomerase reverse transcriptase promoter.
Tumor-Initiating Function of Nucleostemin-Enriched Mammary Tumor Cells.
Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system.
Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells.
Tumor-specific Expression of MicroRNA-26a Suppresses Human Hepatocellular Carcinoma Growth via Cyclin-dependent and -independent Pathways.
Tumor-specific expression of shVEGF and suicide gene as a novel strategy for esophageal cancer therapy.
Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice.
Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter.
Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers.
Tumor-suppressive effect of a telomerase-derived peptide by inhibiting hypoxia-induced HIF-1?-VEGF signaling axis.
Tumor-targeted efficiency of shRNA vector harboring chimera hTERT/U6 promoter.
Tumor-targeted radionuclide imaging and therapy based on human sodium iodide symporter gene driven by a modified telomerase reverse transcriptase promoter.
Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models.
Tumorigenic conversion of endothelial cells.
Tumorigenic effect of TERT and its potential therapeutic target in NSCLC (Review).
Tumour immunotherapy: new tools, new treatment modalities and new T-cell antigens.
Tumour morphology--interplay between chromosome aberrations and founder cell differentiation.
Tumour progression: random mutations or an integrated survival response to cellular stress conserved from unicellular organisms?
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization.
Twisted epithelial-to-mesenchymal transition promotes progression of surviving bladder cancer T24 cells with hTERT-dysfunction.
Two cases of adult Still's disease with abnormally high level of telomerase activity in peripheral blood mononuclear cells.
Two human breast cancer cell lines showing decreasing telomeric repeat length during early in vitro passaging.
Two telomerase-targeting Pt(ii) complexes of jatrorrhizine and berberine derivatives induce apoptosis in human bladder tumor cells.
Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.
Tyrphostin AG1478 suppresses proliferation and invasion of human breast cancer cells.
UBE2D3 is a positive prognostic factor and is negatively correlated with hTERT expression in esophageal cancer.
Ultrasensitive Assay for Telomerase Activity via Self-Enhanced Electrochemiluminescent Ruthenium Complex Doped Metal-Organic Frameworks with High Emission Efficiency.
Ultrasensitive detection of telomerase activity at the single-cell level.
Ultrasensitive detection of telomerase activity in a single cell using stem-loop primer-mediated exponential amplification (SPEA) with near zero nonspecific signal.
Ultrasensitive detection of telomerase activity in lung cancer cells with quencher-free molecular beacon-assisted quadratic signal amplification.
Ultrasensitive Telomerase Activity Detection by Telomeric Elongation Controlled Surface Enhanced Raman Scattering.
Ultrasonographic prediction of highly aggressive telomerase reverse transcriptase (TERT) promoter-mutated papillary thyroid cancer.
Ultrastructural immunolocalization of telomerase and hyaluronate in migrating keratinocytes in a case of oro-pharyngeal squamous cancer.
Ultraviolet irradiation- and dimethyl sulfoxide-induced telomerase activity in ovarian epithelial cell lines.
Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers.
Understanding telomerase in cancer stem cell biology.
Understanding telomere diseases through analysis of patient-derived iPS cells.
Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor.
Universal tumor antigens as targets for immunotherapy.
Universal tumor antigens for cancer vaccination: targeting telomerase for immunoprevention.
Unusual DNA conformations: implications for telomeres.
Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity.
Up-regulating telomerase and tumor suppressors: focusing on anti-aging interventions at the population level.
Up-regulation of hTERT expression by low-dose cisplatin contributes to chemotherapy resistance in human hepatocellular cancer cells.
Up-regulation of human telomerase catalytic subunit during gastric carcinogenesis.
Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene.
Up-regulation of telomerase activity in human pancreatic cancer cells after exposure to etoposide.
Updated Understanding of Cancer as a Metabolic and Telomere-Driven Disease, and Proposal for Complex Personalized Treatment, a Hypothesis.
Upregulated miR-155 inhibits inflammatory response induced by C. albicans in human monocytes derived dendritic cells via targeting p65 and BCL-10.
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss.
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.
Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.
Upregulation of telomerase (hTERT) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus, virus persistence, or disease outcome in cervical cancer.
Upregulation of telomerase function during tissue regeneration.
Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf.
Upstream stimulatory factor (USF) as a transcriptional suppressor of human telomerase reverse transcriptase (hTERT) in oral cancer cells.
Urinary telomerase and its possible role as a marker for bladder cancer.
Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer.
Urine telomerase for diagnosis and surveillance of bladder cancer.
Urine telomerase: an important marker in the diagnosis of bladder cancer.
Urothelial carcinoma of the graft kidney with molecular analyses: a rare case report.
Use of 3D QSAR methodology for data mining the National Cancer Institute Repository of Small Molecules: application to HIV-1 reverse transcriptase inhibition.
Use of hTERT and HPV E6/E7 mRNA RT-qPCR TaqMan Assays in Combination for Diagnosing High-Grade Cervical Lesions and Malignant Tumors.
Use of reverse-transcriptase polymerase chain reaction (RT-PCR) for carcinoembryonic antigen, cytokeratin 19, and maspin in the detection of tumor cells in leukapheresis products from patients with breast cancer: comparison with immunocytochemistry.
Use of telomerase to create bioengineered tissues.
Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells.
Usefulness of Human Telomerase Reverse Transcriptase in Pancreatic Juice as a Biomarker of Pancreatic Malignancy.
Usefulness of immunological detection of the human telomerase reverse transcriptase.
Uses of telomerase peptides in anti-tumor immune therapy.
Using naturally occurring tumours in dogs and cats to study telomerase and cancer stem cell biology.
Using PCR coupled to PAGE for detection and semiquantitative evaluation of telomerase activity.
USP22 down-regulation facilitates human retinoblastoma cell aging and apoptosis via inhibiting TERT/P53 pathway.
Utilizing G-quadruplex formation to target 8-oxoguanine in telomeric sequences.
Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.
Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes.
Validation of telomerase and survivin as anticancer therapeutic targets using ribozymes and small-interfering RNAs.
Variation at the TERT locus and predisposition for cancer.
Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer.
Vascular endothelial growth factor (VEGF) expression and survival in human epithelial ovarian carcinomas.
VEGF- and LPA-induced telomerase in human ovarian cancer cells is Sp1-dependent.
Vertebrate marine species as model systems for studying telomeres and telomerase.
Very low-density lipoprotein receptor in fetal intestine and gastric adenocarcinoma cells.
Vimentin expression is associated with decreased survival in gastric cancer.
Viral small T oncoproteins transform cells by alleviating hippo-pathway-mediated inhibition of the YAP proto-oncogene.
Virus-like particles and macromolecules in human milk and breast tumors.
Virus-specific RNA in selected cell lines derived from RSV-induced tumour.
Visfatin effects on telomerase gene expression in AGS gastric cancer cell line.
Visual and sensitive detection of telomerase activity via hydrogen peroxide test strip.
Visual, Label-Free Telomerase Activity Monitor via Enzymatic Etching of Gold Nanorods.
Visualization of intrathoracically disseminated solid tumors in mice with optical imaging by telomerase-specific amplification of a transferred green fluorescent protein gene.
Visualization of Telomerase Reverse Transcriptase (hTERT) Promoter Activity Using a Trimodality Fusion Reporter Construct.
Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.
Visualizing Human Telomerase Activity with Primer-Modified Au Nanoparticles.
Visualizing telomerase activity for tumour identification by hybridization-triggered ratiometric fluorescence.
Visualizing the down-regulation of hTERT mRNA expression using gold-nanoflare probes and verifying the correlation with cancer cell apoptosis.
Vitamin D and aging.
Vitamin E suppresses telomerase activity in ovarian cancer cells.
Walnut phenolic extracts reduce telomere length and telomerase activity in a colon cancer stem cell model.
Water soluble cationic perylene derivatives as possible telomerase inhibitors: the search for selective G-quadruplex targeting.
Water-soluble benzoheterocycle triosmium clusters as potential inhibitors of telomerase enzyme.
Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis.
Weak telomerase activity in malignant cells in metastatic serous effusions: correlation to short survival time.
What We Know about the Molecular Genetics of Central Nervous System (CNS) Tumours in Malaysia.
When ATPases pontin and reptin met telomerase.
When the Ends Are Really the Beginnings: Targeting Telomerase for Treatment of GBM.
Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development.
Wild-type p16INK4a suppresses cell growth, telomerase activity and DNA repair in human breast cancer MCF-7 cells.
Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences.
Wnt/?-Catenin Signaling Exacerbates Keloid Cell Proliferation by Regulating Telomerase.
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells.
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts.
X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells.
XAV939 promotes apoptosis in a neuroblastoma cell line via telomere shortening.
Xenoantigen, an alphaGal epitope-expression construct driven by the hTERT-promoter, specifically kills human pancreatic cancer cell line.
Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.
Yeast hnRNP-related proteins contribute to the maintenance of telomeres.
YY1 Promotes Telomerase Activity and Laryngeal Squamous Cell Carcinoma Progression Through Impairment of GAS5-Mediated p53 Stability.
Zero-Background Helicase-Dependent Amplification and Its Application to Reliable Assay of Telomerase Activity in Cancer Cell by Eliminating Primer-Dimer Artifacts.
Zidovudine, abacavir and lamivudine increase the radiosensitivity of human esophageal squamous cancer cell lines.
Zoning of mucosal phenotype, dysplasia, and telomerase activity measured by telomerase repeat assay protocol in Barrett's esophagus.
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity.
Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status.
[1997, a good year for telomerase?]
[5,10,15,20-Tetra-(N-methyl-3-pyridyl)porphyrin destabilizes the anti-parallel telomeric quadruplex d(TTAGGG)4].
[A discovery that can result in new therapies. The enzyme telomerase is an important factor in the development of cancer]
[A DNA vector-based RNAi technology to inhibit the activity of the telomerase of cell line HCCLM3]
[A preliminary study on anti-liver cancer immunity of the virus-like particulate peptide-nucleic acid vaccine]
[Actinic keratoses]
[Advance in studies on anti-cancer activity and mechanism of flavonoids].
[Advance in the biology of pancreatic of cancer].
[Advance of research on telomerase]
[Aging or tumor: the crosstalk between telomerase and p53]
[Amplification and clinical significance of hTERC gene in the cervical exfoliated cells from natural population in Shenzhen]
[An experimental study of telomerase reverse transcriptase (hTERT) DNAzyme on growth of A549/DDP cells.]
[Analysis of telomerase activity in esophageal carcinoma using microdissection telomeric repeat amplification protocol assay]
[Analysis of telomeric length in epithelial carcinoma of the ovary]
[Anticancer effect of tanshinone and its mechanisms]
[Antisense hTERT inhibits gene expression and functional activity of telomerase in leukemia cell lines.]
[Apoptosis of laryngeal carcinoma cell line Hep2 induced by tumor-specific expression of TRAIL gene.]
[Apoptotic endonuclease EndoG induces alternative splicing of telomerase catalytic subunit hTERT and death of tumor cells].
[Application of antisense human telomerase RNA toward cancer therapy]
[Application of hammerhead ribozyme targeting telomerase molecule for cancer therapy]
[Application of Van-Clear and xylene in the detection of cervical hTERC gene by fluorescence in situ hybridization].
[Biochemical and physiocochemical characteristics of a type C virus isolated from spontaneous lymphosarcoma of CC57Br strain mice]
[Cell transformation]
[Cellular senescence, cancer and telomerase]
[Characterization of telomerase regulation association gene TRAP and cancer biology]
[Circadian rhythms of DNA synthesis and telomerase expression in hepatic cancer transplanted in nude mice]
[Circulating DNA, telomerase of circulating tumor cells and early diagnosis of tumors]
[Clinical Application and Challenges of Telomere and Telomerase Research ?in Lung Cancer].
[CLINICAL CASE: THE SIDE EFFECTS OF STATINS].
[Clinical implications of telomerase activity in breast cancer fine-needle aspirates]
[Clinical significance of detecting telomerase activity in ascites cells from patients with ovarian carcinoma]
[Clinical significance of human telomerase reverse transcriptase in patients with colon cancer]
[Clinical significance of telomerase activity in lung cancer.]
[Clinical value of gene diagnosis in breast cancer]
[Cloning of alternative isoforms of the catalytic subunit of the human thelomerase (htert)].
[Cloning of human telomerase reverse transcriptase promoter for targeted cancer therapy]
[Cloning, expression of a segment of hTERT gene and detection of telomerase and hTERT by anti-hTERT polyclonal antibody]
[Construction and identification of eukaryotic expression vector for sense and antisense human telomerase reverse transcriptase]
[Construction and screening of a ribozyme targeting telomerase RNA and effects of telomerase ribozyme on proliferation and apoptosis of CNE-2Z cells]
[Construction of an expression vector under the control of hTERT promoter.]
[Construction of tumor cell-specific expression vector modulated by human telomerase reserse transcription gene core promoter.]
[Contemporary study of strengthening body resistance and archaeus herbs on malignant tumor]
[Coordinated expression of c-Myc and telomerase activity in Helicobacter pylori infected gastric diseases]
[Correlation of hTERT expression to maspin and bFGF expression and their significance in glioma]
[Correlations of telomere length and telomerase activity to radiosensitivity of human laryngeal squamous carcinoma cells]
[CTLs induced by hTERT-related multiepitope peptide-sensitived mDCs specifically kill HLA-A24(+); tumor cells.]
[Current diagnostic and therapeutic approaches to invasive bladder cancer]
[Current status of breast cancer chemoprevention]
[Current views on the mechanism of oncogenic cell transformation in ovine pulmonary adenocarcinoma]
[Detection and effect of telomerase activity in oral mucosal squamous cell carcinoma]
[Detection and quantification of human papillomavirus genital infections: Virological, epidemiological, and clinical applications.]
[Detection and significance of HPV16, 18 infection, P53 overexpression and telomerase activity in patients with lung cancer]
[Detection of telomerase activity and its clinical application]
[Detection of telomerase activity in cervical lesions by non-radioactive telomeric repeat amplification protocol (TRAP)]
[Detection of telomerase activity in gastric cancer and adjacent tissues]
[Detection of telomerase activity in intestinal lavage solution from colorectal carcinoma patients]
[Detection of telomerase activity in prostate needle-biopsy samples]
[Detection of telomerase activity in salivary tumor and its significance]
[Detection of telomerase activity in the blood of patients with lung cancer.]
[Detection of telomerase activity level in human non-small-cell lung cancer]
[Detection of telomerase activity of exfoliated cells in bile and its clinical impact]
[Development of in situ TRAP assay detecting telomerase activity in cell]
[Development of noninvasive bladder cancer diagnosis on basis of telomerase and it's subunits hTERT and hTR detection].
[Diagnostic significance of combining telomerase activity with CYFRA21-1 level in differentiating malignant pleural effusion caused by lung cancer from benign pleural effusion]
[Diagnostic significance of telomerase activity and telomere length in endoscopic sample of colorectal cancer]
[Doxycycline Sensitive Two-Promoter Integrator Based on the TET-ON 3G Transactivator].
[Effect of antisense epidermal growth factor receptor cDNA transfection on telomerase activity of glioblastomas cells]
[Effect of cell cycle on telomerase activity of hepatoma cells and its relationship with replication of hepatitis B virus]
[Effect of human telomerase reverse transcriptase gene antisense oligonucleotide on sensitivity of gemcitabine in pancreatic cancer cell]
[Effect of inhibition of polyamine biosynthesis on the growth and telomerase activity of human laryngeal carcinoma cells Hep-2]
[Effect of selenium dioxide on proliferation, apoptosis, and elomerase activity of human lung cancer cell line in vitro]
[Effects of antisense human telomerase reverse-transcript protein subunit (hTERT) gene on biological characteristics of hepatoblastoma cell line in vitro]
[Effects of combining siRNA-TR and TERT upon telomerase activity and in vitro growth inhibition in transitional cancer of bladder BIU-87 cell line]
[Effects of hTERT RNAi on apoptosis of hepatocellular carcinoma cells induced by TRAIL]
[Effects of human telomerase reverse transcriptase promoter and survivin promoter in targeted tumor gene therapy]
[Effects of matrine on the growth inhibition, c-myc and hTERT protein expression in human adenocarcinoma lung cancer cell line A549.]
[Effects of tea polyphenols and tea pigments on telomerase activity of HepG2 cells]
[Effects of telomerase on cell cycle regulation and tumorigenesis]
[Effects of telomerase sense and antisense oligodeoxynucleotides on growth and differentiation of nasopharyngeal carcinoma cells]
[Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]
[Epidemiology of lung cancer in former poison-gas workers and molecular approaches to lung cancer]
[Epidemiology, natural history and pathogenesis of hepatocellular carcinoma]
[Examinations on the importance of the inactivation of the tumor suppressor gene p16, reactivation of the telomerase and mutation of p53 in the pathogenesis of head and neck tumors]
[EXOSOMES AS MEDIATORS OF INTERCELLULAR COMMUNICATION: THE CANCER AND TELOMERASE CONNECTION].
[Experimental Study on Antitumor Effects of Shen Qi Jin Kang (SQJK).]
[Expression of antisense telomerase genes suppressing human cancer malignant phenotypes]
[Expression of dihydropyrimidine dehydrogenase in primary colorectal cancer and liver metastasis--a relationship between mRNA levels in cancer cells and protein levels in cancerous tissue and effect of 5-fluorouracil]
[Expression of hRad21 and clinicopathological analysis in gastrointestinal malignant tumors maintained their telomeres by a mechanism of alternative lengthening of telomeres]
[Expression of human telomerase in lung cancer:A meta-analysis of diagnostic test.]
[Expression of human telomerase reverse transcriptase in cervix cancer and its significance]
[Expression of osm gene driven by hTERT gene promoter inhibits cancer cells proliferation in vitro]
[Expression of TEIF protein in colorectal tumors and its correlation with centrosome abnormality]
[Expression of telomerase activity in thymoma and thymiccarcinoma tissues; a clinicopathological study]
[Expression of telomerase and its RNA in nasopharyngeal carcinoma]
[Expression of telomerase and telomerase associated-regulation protein and proliferating cell nuclear antigen in ovarian epithelial tumors]
[Expression of telomerase genes in human tumors]
[Expression of telomerase reverse transcriptase and its relationship with tumor suppressor gene p53 in HCC]
[Expression of telomere and telomerase in human primary gastric carcinoma]
[Expression of thymidine phosphorylase in primary colorectal cancer and liver metastasis-relationship between mRNA levels in cancer cells and protein levels in cancerous tissue]
[Extension of life-span of normal human fibroblasts by reconstitution of telomerase activity]
[G-quadruplex DNA: myth or reality?]
[G-quadruplex ligands: mechanisms of anticancer action and target binding].
[Genetic and epigenetic factors of cervical tumor progression]
[Genic alterations in oral and head and neck squamous cell carcinomas: analysis of international literature]
[hTERT promoter enhances the radiosensitivity to gene-radiation therapy of human laryngeal carcinoma transplanted in nude mice]
[hTERT promoter-based conditionally replicative adenoviruses are useful for lung cancer and other solid cancer treatment]
[Human senescence, cancer and telomerase]
[Human telomerase reverse transcriptase as a novel target for tumor immunotherapy]
[Identification of telomerase activity in the experimental carcinogenesis of oral cavity]
[IL-4 gene transfer induces the differentiation of cells and inhibits the activity of telomerase in hepatoblastoma cells]
[Immunohistochemical study on telomerase activity in ovarian sex-cord stromal tumors]
[In-vivo tumor imaging by radiolabeled RNA probe targeting telomerase].
[Influence and mechanism of PinX1 gene on the chemotherapy sensitivity of nasopharyngeal carcinoma cells in response to Cisplatin].
[Influence of nicotine addiction on telomerase activity in malignant non-small cell lung tumors]
[Inhibiting expression of human telomerase reverse transcriptase promotes degradation of survivin protein]
[Inhibition effects of phosphorothioate-modified antisense hTR on the telomerase activity and the growth of P3 cells derived from pancreatic cancer in culture]
[Inhibition of hTR activity for suppression of lung cancer cell proliferation using antisense phosphorothioate oligonucleotides]
[Inhibition of lung cancer cell line growth in vitro by telomerase anti-sense oligonucleotides.]
[Inhibition of proliferation of salivary adenoid cystic carcinoma by targeting gene transfer]
[Inhibition of telomerase activity by ribozyme targeted to human telomerase transcriptase]
[Inhibition of telomeres and telomerase. Seeking for new anticancer drugs]
[Inhibitory effect of antisense human telomerase reverse transcriptase(hTERT) on telomerase activity of human pulmonary giant cell carcinoma cell line(PLA-801D)]
[Inhibitory effect of isorhmnetin on telomerase activity of HeLa cells]
[Inhibitory effect of lentivirus-mediated hTERTp-TK combined with hTERTp-tumstatin on human hepatocarcinoma HepG2 cells].
[Life expectancy and aging, scientific and medical aspects]
[Lung cancer: progress in diagnosis and treatment. IV. Related topics: 1. Telomere and telomerase, new targets for diagnosis and treatment of lung cancer]
[Markers of malignancy in pheochromocytomas]
[Measurement of telomerase activity and telomerase reverse transcriptase expression in gastric fluid and tissue for early diagnosis of stomach cancer]
[Mechanism of cell proliferation--cell cycle, oncogenes, and senescence]
[Metformin--new treatment strategies for gynecologic neoplasms].
[Methods of measuring telomere length and telomerase activity--practice and problems]
[Modified quantitative determination of telomerase activity in human head and neck malignant tumor]
[Molecular alterations in esophageal cancer]
[Molecular aspects of hepatocellular carcinoma]
[Molecular biological testing for diagnosis and treatment of urothelial cancer]
[Molecular biology in bladder cancer]
[Molecular mechanisms involved in the regulation of telomerase activity]
[Molecular pathways of pancreatic carcinogenesis]
[Monoclonal antibodies against human telomerase reverse transcriptase: preparation, characterization, and application]
[New molecular targets in pancreatic cancer]
[Oncolytic virotherapy for human solid tumors]
[Physiopathologic implications of telomerase]
[Preliminary research on the effect of antisense oligodeoxynucleotides of tankyrase 1 on tumor growth following intratumoral injection in mice]
[Prognostic and diagnostic value of telomerase in the head and neck cancer]
[Prognostic factors of infiltrating bladder tumors]
[Prognostic factors on surgical treatment for lung cancer]
[Progress in telomerase and the inhibitors]
[Progress on prevention and treatment of Chinese medicine to molecular mechanism of liver cancer]
[Progress on telomere and telomerase]
[Proliferation and hTERT expression in neuroblastoma]
[Prostate-specific antigen and telomerase in prostatic cancers]
[PTEN tumor suppressor gene combined with doxycycline inhibites telomerase activity in human mucoepidermoid carcinoma cell line].
[Qualitative and quantitative analyses of telomerase activity in cultured cells]
[Quantitation of telomerase activity using the polymerase chain reaction-based enzyme immunoassay and its clinical application]
[Quantitative analysis of telomerase activity in exfoliated urothelial cells for the diagnosis of bladder carcinoma]
[Quantitative assay of telomerase activity in head and neck squamous cell carcinoma]
[Quantitative detection of telomerase activity and its association with clinicopathological characteristics in breast cancer]
[Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck]
[Redusome aging: commentaries]
[Relationship among HPV16 infection and Expression of hTERT, p21waf1, Ki67 in cervical intraepithelial neoplasias and squamous cell carcinomas of cervix uteri]
[Relationship between expressions of telomerase genes and apoptosis related genes in mammary ductal atypical hyperplasia]
[Relationship between human telomerase reverse transcriptase transcriptional level and telomerase activity in three ovarian cancer cell lines]
[Relationship between telomerase activity and clinicopathological findings in gastric cancer]
[Relationship between telomere length and clinical and biological characteristics of the cancers with telomerase reactivation]
[Relationships among expressions of hTERT, MDR1, MRP mRNA, and C-myc protein in non-small cell lung cancer.]
[Replicative senescence as a model of aging: the role of oxidative stress and telomere shortening--an overview]
[Significance of telomerase activity detection by fine-needle aspiration in patients with breast cancer]
[Significance of telomerase expression in diagnosis and treatment of breast tumor]
[siRNA targeting telomerase--effective tool in anti-cancer therapy?]
[Specific inhibition of hTERT gene expression by short interfering RNAs in gastric cancer SGC7901 cell]
[Structure and regulation mechanisms of telomerase]
[Studies on telomerase reverse transcriptase components and liver cancer].
[Study of telomerase activity in colorectal carcinomas]
[Study on apoptosis of human cervical carcinoma HeLa cells with RNA interference targeting hTERT.]
[Study on cloning of hTERT promoter and its targeting transcriptional activities in telomerase-positive lung cancer cells]
[Study on growth inhibition of implanted tumor in nude mice by antisense oligodeoxynucleotide targeting telomerase RNA.]
[Study on telomerase activity and its clinical value in human non small cell lung cancer]
[Study on telomerase activity in hepatocellular carcinoma and chronic hepatitic disease]
[Study on telomerase inhibition by ribozyme targeted to telomerase RNA component]
[Study on the correlation between the different papillomavirus type and telomerase in cervical cancer]
[Study on the inhibition of nude mice transplantation tumor growth by telomerase ribozyme]
[Study on the relationship between TK gene regulated by enhanced suicide gene vector and telomerase activity in nasopharyngeal carcinoma cells]
[Suppression of alternative telomere lengthening in cancer cells with reverse transcriptase inhibitors].
[Techniques for detection of telomerase activity in tissue samples. Diagnostic and prognosis importance]
[Telomerase activity and cellular apoptosis of bladder cancers]
[Telomerase activity and determination of cancer in urological neoplasias using exfoliated urinary cells: in situ TRAP assay and its application]
[Telomerase activity and expression of its RNA component in laryngeal cancer]
[Telomerase activity and genomic instability in colorectal cancers]
[Telomerase activity and regulation in human neuroepithelial tumors]
[Telomerase activity and telomere length as diagnostic tumor marker for ovarian tumors]
[Telomerase activity as a novel marker of lung cancer]
[TELOMERASE ACTIVITY AS A POTENTIAL BIOMARKER FOR PREOPERATIVE DIFFERENTIAL DIAGNOSIS OF CYSTIC NEOPLASMS OF THE LIVER].
[Telomerase activity as marker of superficial tumor of the bladder]
[Telomerase Activity Expressed in Acute Leukemia Cell]
[Telomerase activity in benign proliferative breast disease and breast cancer]
[Telomerase activity in cervical cancer and its precursor lesion]
[Telomerase activity in cervical carcinoma and cervical intraepithelial neoplasia and its correlation to classification of koilocytosis]
[Telomerase activity in cervical intraepithelial neoplasia]
[Telomerase activity in colorectal cancer--a semi-quantitative procedure]
[Telomerase activity in esophageal squamous cell carcinoma and in normal esophageal epithelium adjacent to carcinoma]
[Telomerase activity in gastric cancer and premalignant lesions: determination and its clinical significance]
[Telomerase activity in gastrointestinal, bladder and breast carcinomas and their clinical applications]
[Telomerase activity in human gastric and colorectal cancer]
[Telomerase activity in human head and neck squamous cell carcinoma and adjacent tissues]
[Telomerase activity in human non-small cell lung cancer (NSCLC)]
[Telomerase activity in human primary endometrial carcinoma]
[Telomerase activity in human primary lung caner.]
[Telomerase activity in infiltration ductal carcinoma of breast]
[Telomerase activity in liver cancer and the adjacent tissue]
[Telomerase activity in lung cancer and adjacent peritumoral tissues determined by TRAP-SYBR green assay]
[Telomerase activity in oral squamous cell carcinoma and leukoplakia]
[Telomerase activity in rat tongue carcinogenesis]
[Telomerase activity in stool of patients with colorectal cancer]
[Telomerase activity in the uterine cervix and the uterine body]
[Telomerase activity in uveal melanomas]
[Telomerase activity of common malignant tumors]
[Telomerase activity of tumors in the head and neck]
[Telomerase activity, mTert gene expression and the telomere length in mouse mesenchymal stem cells in the late period after ?- and ?,n-irradiation and in the tumors developed from these cells].
[Telomerase and cancer: a therapeutic breakthrough or a cul-de-sac?]
[Telomerase and cancer: correlation or causality?]
[Telomerase and cancer: importance of detection of telomerase activity in pathology]
[Telomerase and cancer]
[Telomerase and gastrointestinal cancer]
[Telomerase and malignant tumors--diagnostic and prognostic role]
[Telomerase and new aspects for tumor biology]
[Telomerase and telomere: their structure and dynamics in health and disease].
[Telomerase and tumor]
[Telomerase antisense inhibition and chemotherapeutic combination treatments for the proliferation of endometrial cancer in vitro and in vivo]
[Telomerase as a tumor marker?]
[Telomerase downregulation during differentiation of leukemia cells]
[Telomerase expression in colorectal tubular adenoma determined by immunohistochemical staining]
[Telomerase expression in various lesions of adrenal cortex]
[Telomerase gene antisense oligodeoxynucleotide down-regulates telomerase activity in HL-60 cells]
[Telomerase in diseases of the digestive system]
[Telomerase in lung cancer. Testing the activity of the "immortaligy enzyme" bronchial biopsies increases the diagnostic yield in cases of suspected peripheral bronchogenic carcinomas]
[Telomerase in tumors: facts and perspectives]
[Telomerase inhibitor]
[Telomerase level versus spliced hTERT-specific RNA forms in cervical carcinoma]
[Telomerase repressor genes]
[Telomerase reverse transcriptase (TERT) promoter mutations in the tumors of human endocrine organs: Biological and prognostic value].
[Telomerase, a universal target in immunotherapy strategies against tumor?]
[Telomerase, aging, cancer]
[Telomerase, cell immortality and cancer]
[Telomerase--new diagnostic and therapeutic options in oncology]
[Telomerase: a new marker for cancer diagnosis]
[Telomerase: a universal tumor antigen for anticancer immunotherapy]
[Telomerase: an enzyme with multiple applications in cancer research]
[Telomerase]
[Telomere and telomerase as targets for anti-cancer drugs]
[Telomere and telomerase associated genes]
[Telomere and telomerase in human cancer]
[Telomere DNA and telomerase of lymphoma-derived cell lines--telomere hypothesis for cell growth control]
[Telomere length and telomerase activity in hepatocellular carcinoma]
[Telomere length and telomerase activity in intestinal metaplasia, adenoma and well differentiated adenocarcinoma of the stomach]
[Telomere lengths and telomerase activity in liposarcomas]
[Telomere Recombination in Normal Mammalian Cells].
[Telomere, telomerase and cancers]
[Telomeres and telomerase activity: their role in aging and in neoplastic development]
[Telomeres and telomerase as targeted therapies in cancer treatment]
[Telomeres and telomerase in leukemias]
[Telomeres and telomerase, new targets for anticancer chemotherapy]
[Telomeres and telomerase: Relevance and future prospects in systemic lupus erythematosus.]
[Telomeres and telomerase]
[Telomeres, telomerase and cancer]
[Telomeres, telomerase and development of cancer]
[Telomeres, telomerase and neoplasms]
[The advance of telomerase research in tumor diagnosis and therapy]
[The advance of tumor development mechanism applying mTR-/- mouse model]
[The diagnostic value of telomerase activity in differentiating benign and malignant ascitic fluid]
[The direct effect of anticancer agents on the telomerase activity in human cancer cell lines]
[The dysplastic nevus. An Ariadne's thread through a conceptual labyrinth]
[The effect of As2O3 on induction of apoptosis and inhibition of telomerase activity in colon cancer LS-174T cells]
[The expressions of telomerase activity and cyclinD1 protein in laryngeal squamous cell carcinoma]
[The influence of compound aITEL1296 on telomerase activity and the growth of cancer cells].
[The inhibitory effect of antisense adenovirus vector of telomerase on telomerase activity in breast cancer cells MCF-7]
[The opposite roles of telomerase during initiation and progression of cancers]
[The role of telomerase activity in non-invasive diagnostics of bladder cancer].
[The role of telomerase for pancreatic carcinogenesis in human and hamster]
[The role of telomeres in cancer].
[The significance of telomerase activity in patients with gastric cancer]
[The study of RNA markers in blood of patients with malignant tumors of gastrointestinal tract].
[The systems of molecular genetic markers under cancer of stomach].
[The value of detecting telomerase activity on early diagnosis of lung cancer.]
[Thyroid carcinomas of the follicular epithelium: tumor markers and oncogenes]
[Tumor-targeted human telomerase reverse transcriptase promoter/tk gene therapy against human nasopharyngeal carcinoma cells in vitro.]
Neoplasms, Germ Cell and Embryonal
Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors.
Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.
Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR.
Targeting telomerase activity by BIBR1532 as a therapeutic approach in germ cell tumors.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity in germ cell cancers and mature teratomas.
The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase.
Neoplasms, Glandular and Epithelial
Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically.
Neoplasms, Muscle Tissue
The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase.
Neoplasms, Neuroepithelial
Differential telomerase expression and telomere length in primary intracranial tumors.
Telomerase activity and alterations in telomere length in human brain tumors.
[Telomerase activity and regulation in human neuroepithelial tumors]
Neoplasms, Squamous Cell
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis.
Human telomerase reverse transcriptase is a promising target for cancer inhibition in squamous cell carcinomas.
The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
Neoplastic Cells, Circulating
A cancer detection platform which measures telomerase activity from live circulating tumor cells captured on a microfilter.
A second chance for telomerase reverse transcriptase in anticancer immunotherapy.
Association between circulating tumor cells and prognosis in patients with stage III melanoma with sentinel lymph node metastasis in a phase III international multicenter trial.
Change in number and size of circulating tumor cells with high telomerase activity during treatment of patients with gastric cancer.
Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: a phase III metastatic castration resistant prostate cancer trial.
Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer.
Combination of CT and telomerase+ circulating tumor cells improves diagnosis of small pulmonary nodules.
Cytokeratin-20 reverse-transcriptase polymerase chain reaction as a new tool for the detection of circulating tumor cells in peripheral blood and bone marrow of bladder cancer patients.
Detection of circulating neoplastic cells by reverse-transcriptase polymerase chain reaction in malignant melanoma: association with clinical stage and prognosis.
Does the presence of circulating tumor cells in the venous drainage of curative colorectal cancer resections determine prognosis? A meta-analysis.
High detection rate of circulating tumor cells in blood of patients with prostate cancer using telomerase activity.
High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab.
Human mammaglobin: a superior marker for reverse-transcriptase PCR in detecting circulating tumor cells in breast cancer patients.
Joint quantitative measurement of hTERT mRNA in both peripheral blood and circulating tumor cells of patients with nasopharyngeal carcinoma and its clinical significance.
Molecular Detection of Circulating Tumor Cells in the Peripheral Blood of Patients with Colorectal Cancer Using RT-PCR: Significance of the Prediction of Postoperative Metastasis.
Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance of the prediction of postoperative metastasis.
Molecular detection of disseminated tumor cells in the peripheral blood of patients with gastric cancer: evaluation of their prognostic significance.
Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse.
Molecular markers of prognosis and therapeutic targets in metastatic colorectal cancer.
Prognostic value of tyrosinase reverse-transcriptase polymerase chain reaction in metastatic melanoma.
The molecular detection of circulating tumor cells in bladder cancer using telomerase activity.
[Circulating DNA, telomerase of circulating tumor cells and early diagnosis of tumors]
[Prognostic factors of infiltrating bladder tumors]
Nephrotic Syndrome
Down-regulation of manganese-superoxide dismutase gene expression in idiopathic nephrotic syndrome.
Nervous System Diseases
Telomeres in neurological disorders.
Neuralgia
?-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain.
A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy.
A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy.
Identification of Key Genes and Pathways in Mouse Spinal Cord Involved in ddC-Induced Neuropathic Pain by Transcriptome Sequencing.
IL-10 mediated by herpes simplex virus vector reduces neuropathic pain induced by HIV gp120 combined with ddC in rats.
Indomethacin plus minocycline coadministration relieves chemotherapy and antiretroviral drug-induced neuropathic pain in a cannabinoid receptors-dependent manner.
Influence of Phosphatidylinositol-3-Kinase/Protein Kinase B-Mammalian Target of Rapamycin Signaling Pathway on the Neuropathic Pain Complicated by Nucleoside Reverse Transcriptase Inhibitors for the Treatment of HIV Infection.
Mechanical allodynia induced by nucleoside reverse transcriptase inhibitor is suppressed by p55TNFSR mediated by herpes simplex virus vector through the SDF1?/CXCR4 system in rats.
Spinal CPEB-mtROS-CBP signaling pathway contributes to perineural HIV gp120 with ddC-related neuropathic pain in rats.
TNF? is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats.
Neurilemmoma
Correlation of clinical features and telomerase activity in human gliomas.
Differential telomerase expression and telomere length in primary intracranial tumors.
Implication of telomere length as a proliferation-associated marker in schwannomas.
Telomerase activity in 144 brain tumours.
[Significance of modern methods for laboratory detection of rabies agents and identification of the zoonose immunological survey].
Neuroblastoma
A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.
Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma.
Age-dependent accumulation of genomic aberrations and deregulation of cell cycle and telomerase genes in metastatic neuroblastoma.
ALK Protein Expression is Related to Neuroblastoma Aggressiveness, But is Not Independent Prognostic Factor.
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
ARID1A-SIN3A drives retinoic acid-induced neuroblastoma differentiation by transcriptional repression of TERT.
Association of telomerase activity with radio- and chemosensitivity of neuroblastomas.
Clinical utility of telomerase in cancer.
Comparative genomic hybridization and telomerase activity analysis identify two biologically different groups of 4s neuroblastomas.
Comparison of telomerase levels before and after differentiation of two cell lines of human neuroblastoma.
Correlating telomerase activity levels with human neuroblastoma outcomes.
Curcumin regulates low-linear energy transfer ?-radiation-induced NF?B-dependent telomerase activity in human neuroblastoma cells.
Detection of neuroblastoma cells during clinical follow up: advanced flow cytometry and rt-PCR for tyrosine hydroxylase using both conventional and real-time PCR.
Differential gene expression profiles between neuroblastomas with high telomerase activity and low telomerase activity.
Direct recruitment of N-myc to target gene promoters.
Epigenetic Targeting of TERT-Associated Gene Expression Signature in Human Neuroblastoma with TERT Overexpression.
Expression of the human telomerase reverse transcriptase in pheochromocytoma and neuroblastoma tissues.
Full-length telomerase reverse transcriptase messenger RNA is an independent prognostic factor in neuroblastoma.
Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay.
How Do Telomere Abnormalities Regulate the Biology of Neuroblastoma?
HuB and HuD repress telomerase activity by dissociating HuR from TERC.
Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming.
Inhibition of telomerase causes vulnerability to endoplasmic reticulum stress-induced neuronal cell death.
Involvement of endogenous ceramide in the inhibition of telomerase activity and induction of morphologic differentiation in response to all-trans-retinoic acid in human neuroblastoma cells.
Mechanisms of neuroblastoma regression.
miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo.
Multifocal neuroblastoma: biologic behavior and surgical aspects.
Murine intracisternal type A particles: a biochemical characterization.
Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma.
Nuclear condensation and cell cycle arrest induced by telomerase siRNA in neuroblastoma cells.
Prognostic impact of telomerase activity in patients with neuroblastoma.
Prognostic significance of MYCN oncogene expression in childhood neuroblastoma.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Rapid detection of MYCN gene amplification and telomerase expression in neuroblastoma.
Regulation of telomerase activity by alternate splicing of human telomerase reverse transcriptase mRNA in a subset of neuroblastomas.
Retinoids induce differentiation and downregulate telomerase activity and N-Myc to increase sensitivity to flavonoids for apoptosis in human malignant neuroblastoma SH-SY5Y cells.
Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines.
Sequential hTERT Knockdown and Apigenin Treatment Inhibited Invasion and Proliferation and Induced Apoptosis in Human Malignant Neuroblastoma SK-N-DZ and SK-N-BE2 Cells.
snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.
Spontaneous regression of neuroblastoma.
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity and telomerase subunits gene expression patterns in neuroblastoma: a molecular and immunohistochemical study establishing prognostic tools for fresh-frozen and paraffin-embedded tissues.
Telomerase activity as a prognostic factor in neuroblastomas.
Telomerase activity by TRAP assay and telomerase RNA (hTR) expression are predictive of outcome in neuroblastoma.
Telomerase activity distinguishes between neuroblastomas with good and poor prognosis.
Telomerase activity in human gliomas.
Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour?
Telomerase and telomere length in multiple myeloma: correlations with disease heterogeneity, cytogenetic status, and overall survival.
Telomerase expression as complementary prognostic factor in neuroblastoma.
Telomerase expression in primary neuroblastomas.
Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells.
Telomerase is a strong indicator for assessing the proneness to progression in neuroblastomas.
Telomerase. A target for anticancer therapy.
Telomere biology including TERT rearrangements in neuroblastoma: a useful indicator for surgical treatments.
Telomere length is a prognostic factor in neuroblastoma.
Telomere Maintenance in Pediatric Cancer.
TERT promotor region rearrangements analyzed in high-risk neuroblastomas by FISH method and whole genome sequencing.
XAV939 promotes apoptosis in a neuroblastoma cell line via telomere shortening.
[Proliferation and hTERT expression in neuroblastoma]
Neurodegenerative Diseases
Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy.
Mesenchymal Stem Cells Could Be Considered as a Candidate for Further Studies in Cell-Based Therapy of Alzheimer's Disease via Targeting the Signaling Pathways.
Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus.
Novel Neuroendocrine and Metabolic Mechanism Provides the Patented Platform for Important Rejuvenation Therapies: Targeted Therapy of Telomere Attrition and Lifestyle Changes of Telomerase Activity with the Timing of Neuron-Specific Imidazole-Containing Dipeptide-Dominant Pharmaconutrition Provision.
Potential roles of telomeres and telomerase in neurodegenerative diseases.
Role of Senescence and Neuroprotective Effects of Telomerase in Neurodegenerative Diseases.
Telomerase and neuronal marker status of differentiated NT2 and SK-N-SH human neuronal cells and primary human neurons.
Telomerase in Brain: The New Kid on the Block and Its Role in Neurodegenerative Diseases.
Neuroectodermal Tumors, Primitive
Differential telomerase expression in human primary intracranial tumors.
Molecular analysis of PinX1 in medulloblastomas.
Telomerase activity and alterations in telomere length in human brain tumors.
Telomere maintenance in childhood primitive neuroectodermal brain tumors.
The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells.
Neuroectodermal Tumors, Primitive, Peripheral
Detection of circulating tumor cells in patients with Ewing's sarcoma and peripheral primitive neuroectodermal tumor.
In situ reverse-transcriptase polymerase chain reaction demonstration of the EWS/FLI-1 fusion transcript in Ewing's sarcomas and peripheral primitive neuroectodermal tumors.
Neuroendocrine Tumors
Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations.
Telomerase activity in neuroendocrine tumors.
Telomerase activity in pulmonary neuroendocrine tumors: correlation with histologic subtype (MS-0060).
Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors.
Telomere length, telomerase activity, and expressions of human telomerase mRNA component (hTERC) and human telomerase reverse transcriptase (hTERT) mRNA in pulmonary neuroendocrine tumors.
Neurofibroma
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.
Neurofibroma, Plexiform
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.
Neurofibromatoses
Glioblastoma in a female neurofibromatosis 1 patient without IDH1, BRAF V600E, and TERT promoter mutations: A case report.
Pigmentary disorders of the eyes and skin.
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.
Telomerase Dysfunction in the Tumorigenesis of Genetic Disorders.
Neurofibromatosis 1
Glioblastoma in a female neurofibromatosis 1 patient without IDH1, BRAF V600E, and TERT promoter mutations: A case report.
Pigmentary disorders of the eyes and skin.
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.
Neurofibromatosis 2
Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers.
Neurofibrosarcoma
Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.
Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals.
Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance.
Neuroinflammatory Diseases
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Induce Pathological Pain through Wnt5a-Mediated Neuroinflammation in Aging Mice.
Quercetin attenuates AZT-induced neuroinflammation in the CNS.
Neuroma, Acoustic
Plasma miR-185 as a predictive biomarker for prognosis of malignant glioma.
Neutropenia
A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish.
Abnormal telomere shortening of peripheral blood mononuclear cells and granulocytes in patients with chronic idiopathic neutropenia.
Managing issues related to antiretroviral therapy.
Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow.
Nevi and Melanomas
hTERT expression in melanocytic lesions: an immunohistochemical study on paraffin-embedded tissue.
Telomerase activity in melanocytic lesions: A potential marker of tumor biology.
Nevus
Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions.
Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.
Evaluation of telomerase activity in cutaneous melanocytic proliferations.
hTERT expression in melanocytic lesions: an immunohistochemical study on paraffin-embedded tissue.
Human telomerase RNA component expression in Spitz nevi, common melanocytic nevi, and malignant melanomas.
Spontaneous regression of cutaneous melanoma in sinclair swine is associated with defective telomerase activity and extensive telomere erosion.
Telomerase activity and expression of apoptosis and anti-apoptosis regulators in the progression pathway of human melanoma.
Telomerase activity in melanocytic lesions: A potential marker of tumor biology.
Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi.
Telomerase Expression in a Series of Melanocytic Neoplasms.
[Significance of human telomerase RNA expression in situ in malignant melanoma]
Nevus, Intradermal
Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions.
Nevus, Pigmented
Human telomerase RNA component expression in Spitz nevi, common melanocytic nevi, and malignant melanomas.
Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.
Newcastle Disease
Anti-tumor effects of an oncolytic adenovirus expressing hemagglutinin-neuraminidase of Newcastle disease virus in vitro and in vivo.
RNA-dependent DNA polymerase activity in preparations of a mutant of Newcastle disease virus arising from persistently infected L cells.
Nijmegen Breakage Syndrome
Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit.
Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures.
Non-alcoholic Fatty Liver Disease
Activated carbon N-acetylcysteine microcapsule protects against nonalcoholic fatty liver disease in young rats via activating telomerase and inhibiting apoptosis.
Hepatic histopathology and clinical characteristics associated with antiretroviral therapy in HIV patients without viral hepatitis.
Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors.
Nonalcoholic fatty liver disease in HIV-infected patients referred to a metabolic clinic: prevalence, characteristics, and predictors.
Nonalcoholic fatty liver disease in HIV-infected persons: epidemiology and the role of nucleoside reverse transcriptase inhibitors.
Nonalcoholic Steatohepatitis: Involvement of the Telomerase and Proinflammatory Mediators.
Parenteral Soybean Oil Induces Hepatosteatosis Despite Addition of Fish Oil in a Mouse Model of Intestinal Failure-Associated Liver Disease.
Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.
Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease.
Telomerase: a key player in the pathogenesis of non-alcoholic fatty liver disease?
Obesity
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance.
Association of telomere length and telomerase methylation with n-3 fatty acids in preschool children with obesity.
Associations of TERC Single Nucleotide Polymorphisms with Human Leukocyte Telomere Length and the Risk of Type 2 Diabetes Mellitus.
Atorvastatin reverses high cholesterol-induced cardiac remodelling and regulates mitochondrial quality-control in a cholesterol-independent manner: An experimental study.
Canine leptin: cDNA cloning, expression and activity of recombinant protein.
Hepatic histopathology and clinical characteristics associated with antiretroviral therapy in HIV patients without viral hepatitis.
High-fat diet induced obesity and age influence the telomere shelterin complex and telomerase gene expression in mouse adipose tissue.
HIV and antiretroviral therapy-related fat alterations.
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Plasma Leptin, hTERT Gene Expression, and Anthropometric Measures in Obese and Non-Obese Women with Breast Cancer.
Obesity, Abdominal
Prevalence and factors associated with physical function limitation in older West African people living with HIV.
Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: a prospective cohort study.
Obstetric Labor, Premature
Maternal human telomerase reverse transcriptase variants are associated with preterm labor and preterm premature rupture of membranes.
Odontogenic Tumors
Molecular and genetic aspects of odontogenic tumors: a review.
Molecular pathology of odontogenic tumors.
Oligodendroglioma
Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461.
Clinical significance of ABCA2' a possible molecular marker for oligodendrogliomas.
Correlation between IDH, ATRX, and TERT promoter mutations in glioma.
Differential telomerase expression in human primary intracranial tumors.
Droplet digital PCR assay for detecting TERT promoter mutations in patients with glioma.
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase.
Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis.
Molecular Testing of Brain Tumor.
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Oligodendroglioma showing pleomorphic xanthoastrocytoma-like perivascular microlesion: With IDH1, TERT promoter mutation and 1p/19q codeletion detected in both components.
Part II. Telomerase expression in cerebrospinal fluid specimens as an adjunct to cytologic diagnosis.
Prognostic significance of telomerase in brain tumors
Telomerase activity and alterations in telomere length in human brain tumors.
Telomerase activity in human brain tumours.
Telomerase activity in human gliomas.
Telomerase expression in gliomas including the nonastrocytic tumors.
Telomerase expression shows differences across multiple regions of oligodendroglioma versus high grade astrocytomas but shows correlation with Mib-1 labelling.
The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas.
The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.
The significant role of telomerase activity in human brain tumors.
Oligospermia
Telomerase activity in the testis of infertile patients with selected causes.
Opportunistic Infections
Changing patterns in the neuropathogenesis of HIV during the HAART era.
Newer aminopyrimidinimino isatin analogues as non-nucleoside HIV-1 reverse transcriptase inhibitors for HIV and other opportunistic infections of AIDS: design, synthesis and biological evaluation.
Safety and antiretroviral effectiveness of concomitant use of rifampicin and efavirenz for antiretroviral-naive patients in India who are coinfected with tuberculosis and HIV-1.
Short telomere syndromes cause a primary T cell immunodeficiency.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Treatment of HIV-1-associated microsporidiosis and cryptosporidiosis with combination antiretroviral therapy.
Oral Submucous Fibrosis
Immunohistochemical detection of human telomerase reverse transcriptase in oral cancer and pre-cancer.
Orthomyxoviridae Infections
Emerging antiviral drugs.
Osteoarthritis
Evaluation of synovial cytokine patterns in rheumatoid arthritis and osteoarthritis by quantitative reverse transcription polymerase chain reaction.
Heparanase is expressed in adult human osteoarthritic cartilage and drives catabolic responses in primary chondrocytes.
Telomerase Activity in Articular Chondrocytes Is Lost after Puberty.
Telomerase activity in rheumatoid synovium correlates with the mononuclear cell infiltration level and disease aggressiveness of rheumatoid arthritis.
Telomerase activity in the synovial tissues of chronic inflammatory and non-inflammatory rheumatic diseases.
Telomerase transduced osteoarthritis fibroblast-like synoviocytes display a distinct gene expression profile.
Telomere length and telomerase activity in osteoporosis and osteoarthritis.
The role of telomeres in musculoskeletal diseases.
Osteoblastoma
Telomerase activity in benign bone tumors and tumor-like lesions.
Osteochondroma
Chondrosarcoma is not characterized by detectable telomerase activity.
Telomerase activity in benign bone tumors and tumor-like lesions.
Osteonecrosis
Osteonecrosis in patients with human immunodeficiency virus type 1 infection in Taiwan.
Symptomatic bone disorders in HIV-infected patients: incidence in the Aquitaine cohort (1999-2002).
Osteoporosis
A common variant in the telomerase RNA component is associated with short telomere length.
Can telomere length predict bone health? A review of current evidence.
Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Extracellular vesicles from deciduous pulp stem cells recover bone loss by regulating telomerase activity in an osteoporosis mouse model.
In vitro proliferation and differentiation potential of bone marrow-derived mesenchymal stem cells from ovariectomized rats.
LncRNA TERC alleviates the progression of osteoporosis by absorbing miRNA-217 to upregulate RUNX2.
Proliferation and differentiation of rat osteoporosis mesenchymal stem cells (MSCs) after telomerase reverse transcriptase (TERT) transfection.
Telomerase-deficient mice exhibit bone loss due to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Telomere length and telomerase activity in osteoporosis and osteoarthritis.
The role of telomeres in musculoskeletal diseases.
Osteoporosis, Postmenopausal
Extracellular vesicles from deciduous pulp stem cells recover bone loss by regulating telomerase activity in an osteoporosis mouse model.
Osteosarcoma
Accurate Identification and Early Diagnosis of Osteosarcoma through CRISPR-Cas12a-Based Average Telomerase Activity Detection.
Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas.
Analysis of telomerase activity and telomere length in bone and soft tissue tumors.
Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines.
Characterization of human multicentric osteosarcoma using newly established cells derived from multicentric osteosarcoma.
Content Determination of Active Component in Huangqi Yinyanghuo Group and Its Effects on hTERT and Bcl-2 Protein in Osteosarcoma.
Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas.
Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity.
Expression of human telomerase reverse transcriptase splice variants is well correlated with low telomerase activity in osteosarcoma cell lines.
Hepatic angiomyolipoma in a 26-year-old Caucasian woman with a history of tibial osteosarcoma.
hTERT promoter activity identifies osteosarcoma cells with increased EMT characteristics.
Impact of telomerase status on canine osteosarcoma patients.
Increased telomerase activity is not directly related to metastatic potential in rat transplantable osteosarcomas.
Inhibition of cell growth and telomerase activity in osteosarcoma cells by DN-hTERT.
Kruppel-Like Factor 9 Loss-of-Expression in Human Endometrial Carcinoma Links Altered Expression of Growth-Regulatory Genes with Aberrant Proliferative Response to Estrogen.
Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin.
Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient with high telomerase activities.
Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness.
Purification and biochemical characterization of a virus-specific reverse transcriptase from human osteosarcoma tissue.
Repression of telomerase activity during in vitro differentiation of osteosarcoma cells.
Reversible downregulation of telomerase activity by hyperthermia in osteosarcoma cells.
Revertants of human cells transformed by murine sarcoma virus.
shRNA-mediated silencing of hTERT suppresses proliferation and promotes apoptosis in osteosarcoma cells.
Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach.
Suramin suppresses growth, alkaline-phosphatase and telomerase activity of human osteosarcoma cells in vitro.
Telomerase Activation in Malignant Bone Tumors.
Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients.
Telomerase activity correlates with growth of transplantable osteosarcomas in rats treated with cis-diammine dichloroplatinum or the angiogenesis inhibitor AGM-1470.
Telomerase activity in canine osteosarcoma.
Telomerase activity in juxtacortical and conventional high-grade osteosarcomas: correlation with grade, proliferative activity and clinical response to chemotherapy.
Telomerase activity in oral cancer.
Telomerase activity in skeletal sarcomas.
Telomerase expression predicts unfavorable outcome in osteosarcoma.
Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells.
Telomerase, p53 and PCNA activity in osteosarcoma.
Telomere biology of pediatric cancer.
Telomere maintenance in telomerase-positive human ovarian SKOV-3 cells cannot be retarded by complete inhibition of telomerase.
The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma.
The role of telomeres in musculoskeletal diseases.
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity.
Osteosarcoma, Juxtacortical
Telomerase activity in juxtacortical and conventional high-grade osteosarcomas: correlation with grade, proliferative activity and clinical response to chemotherapy.
Otitis Media
Expression of telomerase activity in cholesteatoma otitis media.
Otosclerosis
Histologic otosclerosis is associated with the presence of measles virus in the stapes footplate.
Two subgroups of stapes fixation: otosclerosis and pseudo-otosclerosis.
Ovarian Cysts
Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors.
Quantitative differences in telomerase activity among malignant, premalignant, and benign ovarian lesions.
Telomerase activity in gynecological tumors.
Ovarian Diseases
Telomerase activity determined by conventional telomeric repeat amplification protocol and reverse transcriptase-polymerase chain reaction assay in ovarian lesions: a comparison of assays.
Ovarian Neoplasms
1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498.
2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells.
A genetically defined model for human ovarian cancer.
A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.
A Study of hTERT Promoter Methylation in Circulating Tumour DNAs of Patients with Ovarian Magnificent Tumour.
Activity of telomerase and extracellular regulated protein kinases in parental and drug resistant cells of leukemia and ovarian cancer.
Activity of telomerase in ovarian cancer cells. Clinical implications.
Adenovirus-mediated suicide gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter induced apoptosis of ovarian cancer cell line.
Alteration of telomerase activity associated with development and extension of epithelial ovarian cancer.
Alteration of telomerase activity in ovarian cancer after chemotherapy.
Androgens stimulate telomerase expression, activity and phosphorylation in ovarian adenocarcinoma cells.
Applications of the telomerase assay in peritoneal washing fluids.
Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells.
Autocatalytic caspase-3 driven by human telomerase reverse transcriptase promoter suppresses human ovarian carcinoma growth in vitro and in mice.
Bmi-1 siRNA inhibited ovarian cancer cell line growth and decreased telomerase activity.
Calcium-mediated telomerase activity in ovarian epithelial cells.
Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft.
Correlation of Bmi-1 expression and telomerase activity in human ovarian cancer.
Correlation of chemosensitivity to anticancer drugs and telomere length, telomerase activity and telomerase RNA expression in human ovarian cancer cells.
Correlations of BMI-1 expression and telomerase activity in ovarian cancer tissues.
Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination.
Down-regulation of telomerase activity by anticancer drugs in human ovarian cancer cells.
Dynamic telomerase gene suppression via network effects of GSK3 inhibition.
Effect of 3`-Azido-3`-Deoxythymidine (AZT) on Telomerase Activity and Proliferation of HO-8910 Cell Line of Ovarian Cancer.
Effect of all-trans retinoic acid on telomerase activity in ovarian cancer cells.
Effects of melatonin on the proliferation and cis-diamminedichloroplatinum (CDDP) sensitivity of cultured human ovarian cancer cells.
Eribulin mesylate targets human telomerase reverse transcriptase in ovarian cancer cells.
Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors.
Genomic instability is associated with lack of telomerase activation in ovarian cancer.
Growth Arrest in Ovarian Cancer Cells by hTERT Inhibition Short-Hairpin RNA Targeting Human Telomerase Reverse Transcriptase Induces Immediate Growth Inhibition but not Necessarily Induces Apoptosis in Ovarian Cancer Cells.
Growth arrest in ovarian cancer cells by hTERT inhibition short-hairpin RNA targeting human telomerase reverse transcriptase induces immediate growth inhibition but not necessarily induces apoptosis in ovarian cancer cells.
Herbal complex suppresses telomerase activity in chemo-endocrine resistant cancer cell lines.
Human telomerase inhibition by substituted acridine derivatives.
Human telomerase reverse transcriptase mRNA expression assessed by real-time reverse transcription polymerase chain reaction predicts chemosensitivity in patients with ovarian carcinoma.
Human telomerase reverse transcriptase promoter regulation in normal and malignant human ovarian epithelial cells.
In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.
In vitro effects of gonadotropin-releasing hormone (GnRH) analogue on cancer cell sensitivity to cis-platinum.
Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines.
Induction of ovarian cancer cell apoptosis by 1,25-dihydroxyvitamin D3 through the down-regulation of telomerase.
Inhibition of human telomerase reverse transcriptase gene expression by BRCA1 in human ovarian cancer cells.
Inhibition of human telomerase reverse transcriptase in vivo and in vitro for retroviral vector-based antisense oligonucleotide therapy in ovarian cancer.
Knockdown of p53 combined with expression of the catalytic subunit of telomerase is sufficient to immortalize primary human ovarian surface epithelial cells.
Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients.
Leukocyte telomere length in a population-based case-control study of ovarian cancer: a pilot study.
Lysophosphatidic acid activates telomerase in ovarian cancer cells through hypoxia-inducible factor-1alpha and the PI3K pathway.
MicroRNA-532 and microRNA-3064 inhibit cell proliferation and invasion by acting as direct regulators of human telomerase reverse transcriptase in ovarian cancer.
MiR-124-3p.1 Sensitizes Ovarian Cancer Cells to Mitochondrial Apoptosis Induced by Carboplatin.
Ovarian cancer treatment with a tumor-targeting and gene expression-controllable lipoplex.
p21(WAF1) is involved in interferon-?- induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression in ovarian cancer.
p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma.
Polygala tenuifolia polysaccharide (PTP) inhibits cell proliferation by repressing Bmi-1 expression and downregulating telomerase activity.
Pyk2/ERK 1/2 mediate Sp1- and c-Myc-dependent induction of telomerase activity by epidermal growth factor.
Quantitative differences in telomerase activity among malignant, premalignant, and benign ovarian lesions.
Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest.
Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells.
Role of Apoptotic Regulators in Human Epithelial Ovarian Cancer.
Selective suppression of autocatalytic caspase-3 driven by two-step transcriptional amplified human telomerase reverse transcriptase promoter on ovarian carcinoma growth in vitro and in mice.
Targeted inhibition of telomerase activity combined with chemotherapy demonstrates synergy in eliminating ovarian cancer spheroid-forming cells.
Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity.
Telomerase activity and p53-dependent apoptosis in ovarian cancer cells.
Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents.
Telomerase activity and telomere length in human tumor cells with acquired resistance to anticancer agents.
Telomerase activity in body cavity fluid and peritoneal washings in uterine and ovarian cancer.
Telomerase activity in gynecological tumors.
Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors.
Telomerase in the ovary.
The effect of 17 sesquiterpenes on cell viability and telomerase activity in the human ovarian cancer cell line HO-8910.
The telomerase activity and expression of hTERT gene can serve as indicators in the anti-cancer treatment of human ovarian cancer.
VEGF- and LPA-induced telomerase in human ovarian cancer cells is Sp1-dependent.
Vitamin D receptor is a novel drug target for ovarian cancer treatment.
Vitamin D suppresses leptin stimulation of cancer growth through microRNA.
Vitamin E suppresses telomerase activity in ovarian cancer cells.
[Antisense oligodeoxynucleotides of human telomerse catalytic sub-unit inhibits telomerase activity and proliferation in SKOV3 and COC1]
[Construction of autocatalytic caspase-3 driven by amplified human telomerase reverse transcriptase promoter and its enhanced efficacy of inducing apoptosis in human ovarian carcinoma]
[Construction of TRAIL gene eukaryotic expression vector modulated by hTERT gene core promoter and its effect on apoptosis of ovarian cancer cells.]
[Effects of wogonin on inducing apoptosis of human ovarian cancer A2780 cells and telomerase activity]
[Expression of TRAIL gene eukaryotic expression vector modulated by the human telomerase reverse transcriptase gene core promoter in ovarian cancer cell line SKOV3]
[In vitro treatment of ovarian cancer cells with cytosine deaminase-thymidine kinase fusion disuicide gene therapy system under the control of human telomerase reverse transcriptase gene promoter]
[Relationship between human telomerase reverse transcriptase transcriptional level and telomerase activity in three ovarian cancer cell lines]
[Synergism of antitumor effects on ovarian carcinoma using autocatalytic caspase-3 combined with flavopiridol].
[The efficacy of autocatalytic casapse-3 driven by human telomerase reverse transcriptase promoter on human ovarian carcinoma]
[Treatment of ovarian cancer cell line Skov3 with HSV-tk/GCV under the control of human telomerase reverse transcriptase gene promoter]
Overweight
Increased telomerase activity and vitamin D supplementation in overweight African Americans.
Paget Disease, Extramammary
Expression of survivin and human telomerase reverse transcriptase in extramammary Paget's disease.
Pancreatic Cyst
Cyst fluid telomerase activity predicts the histologic grade of cystic neoplasms of the pancreas.
Pancreatic Diseases
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer.
Diagnosis of pancreatic cancer by detecting telomerase activity in pancreatic juice: comparison with K-ras mutations.
In situ telomerase activity in pancreatic juice may discriminate pancreatic cancer from other pancreatic diseases.
Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer.
Telomerase activity as a marker for differential diagnosis of pancreatic adenocarcinoma: a systematic review and meta-analysis.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity in pure pancreatic juice for the diagnosis of pancreatic cancer may be complementary to K-ras mutation.
Telomerase reactivation is associated with hepatobiliary and pancreatic cancers.
TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.
[Specific activation of telomerase in pancreatic cancer tissue and preoperative diagnosis of pancreatic cancer by telomerase in pancreatic juice]
[Telomerase activity in pancreatic juice for the preoperative diagnosis of pancreatic cancer]
Pancreatic Intraductal Neoplasms
Mixed ductal-endocrine carcinoma derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas identified by human telomerase reverse transcriptase (hTERT) expression.
Pancreatic Neoplasms
9-Hydroxyellipticine inhibits telomerase activity in human pancreatic cancer cells.
ABO blood group and other genetic variants associated with pancreatic cancer.
ACV-TP-T, a thymidine analogue pro-drug activated by telomerase, reduces pancreatic tumor growth in mice.
Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells.
Adrenomedullin is Upregulated in Patients with Pancreatic Cancer and Causes Insulin Resistance in ? Cells and Mice.
Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells.
Association between CLPTM1L-TERT rs401681 polymorphism and pancreatic cancer risk among Chinese Han population.
Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells.
Can inhibition of telomerase increase pancreatic cancer cell's susceptibility to chemotherapeutic reagents?
Cigarette smoke components inhibited intercellular communication and differentiation in human pancreatic ductal epithelial cells.
Circular RNA PCDH10 regulates the tumorigenesis of pancreatic cancer through the miR-338-3p/hTERT axis.
Clinical usefulness of telomerase for the detection of colon cancer in ulcerative colitis patients.
Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer.
Detection of K-ras point mutation and telomerase activity during endoscopic retrograde cholangiopancreatography in diagnosis of pancreatic cancer.
Detection of telomerase activity in patients with pancreatic cancer.
Determination of qualitative telomerase activity as an adjunct to the diagnosis of pancreatic adenocarcinoma by EUS-guided fine-needle aspiration.
Diagnosis of pancreatic cancer by cytology and telomerase activity in exfoliated cells obtained by pancreatic duct brushing during endoscopy.
Diagnosis of pancreatic cancer by detecting telomerase activity in pancreatic juice: comparison with K-ras mutations.
Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells.
Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer.
Expression of telomerase & its significance in the diagnosis of pancreatic cancer.
Gastrin regulates growth of human pancreatic cancer in a tonic and autocrine fashion.
Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial.
Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter.
Genetic diagnosis of pancreatic cancer using specimens obtained by EUS-FNA.
Genetic diagnosis of pancreatic cancer.
hTERT-siRNA Could Potentiate the Cytotoxic Effect of Gemcitabine to Pancreatic Cancer Cells Bxpc-3.
In situ telomerase activity in pancreatic juice may discriminate pancreatic cancer from other pancreatic diseases.
Increased telomerase activities in human pancreatic duct adenocarcinomas.
Induction and expression of cyclin D3 in human pancreatic cancer.
Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.
Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity.
Inhibition of Telomerase Activity by Oleanane Triterpenoid CDDO-Me in Pancreatic Cancer Cells is ROS-Dependent.
Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells.
Inhibitory effects of antisense phosphorothioate oligodeoxynucleotides on pancreatic cancer cell Bxpc-3 telomerase activity and cell growth in vitro.
KLF4? Up-Regulation Promotes Cell Cycle Progression and Reduces Survival Time of Patients With Pancreatic Cancer.
Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2.
Leucocyte telomere length, genetic variants at the
Long-term survival of pancreatic cancer patient diagnosed by positive telomerase activity of pancreatic juice.
Loss of ONECUT1 expression in human pancreatic cancer cells.
Molecular diagnosis of pancreatic cancer.
Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines in in vitro culture.
P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma.
Pancreatic cancer susceptibility loci and their role in survival.
Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 in pancreatic cancer.
PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity.
Positive regulation of human telomerase reverse transcriptase gene expression and telomerase activity by DNA methylation in pancreatic cancer.
Quantitative analysis of human telomerase reverse transcriptase in pancreatic cancer.
Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer.
Quantitative assessment of the diagnostic role of human telomerase activity from pancreatic juice in pancreatic cancer.
RBM10 regulates human TERT gene splicing and inhibits pancreatic cancer progression.
Real-time quantitative PCR of telomerase mRNA is useful for the differentiation of benign and malignant pancreatic disorders.
Reduced miRNA-218 expression in pancreatic cancer patients as a predictor of poor prognosis.
Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells.
Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma.
Semi-quantitative analysis of telomerase in pancreatic ductal adenocarcinoma.
Stable expression of antisense hTR inhibits in vitro pancreatic cancer cell growth.
Targeting claudin-4 in human pancreatic cancer.
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients.
Telomerase activity as a marker for differential diagnosis of pancreatic adenocarcinoma: a systematic review and meta-analysis.
Telomerase activity detected in pancreatic juice 19 months before a tumor is detected in a patient with pancreatic cancer.
Telomerase activity for the preoperative diagnosis of pancreatic cancer.
Telomerase activity in pancreatic juice differentiates pancreatic cancer from chronic pancreatitis: A meta-analysis.
Telomerase activity in pure pancreatic juice for the diagnosis of pancreatic cancer may be complementary to K-ras mutation.
Telomerase activity in the differential diagnosis of pancreatic mass.
Telomerase activity is detected in pancreatic cancer but not in benign tumors.
Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells.
Telomerase as a new target for pancreatic cancer treatment.
Telomerase elevation in pancreatic ductal carcinoma compared to nonmalignant pathological states.
Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells.
Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: A dose escalating phase I/II study.
Telomerase reactivation is associated with hepatobiliary and pancreatic cancers.
Telomerase reverse transcriptase and telomeric-repeat binding factor protein 1 as regulators of telomerase activity in pancreatic cancer cells.
Telomerase transcriptional targeting of inducible Bax/TRAIL gene therapy improves gemcitabine treatment of pancreatic cancer.
TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.
The detection of telomerase activity in patients with adenocarcinoma of the pancreas by fine needle aspiration.
The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.
Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target.
Up-regulation of telomerase activity in human pancreatic cancer cells after exposure to etoposide.
Usefulness of Human Telomerase Reverse Transcriptase in Pancreatic Juice as a Biomarker of Pancreatic Malignancy.
Vitamin D receptor is expressed in pancreatic cancer cells and a vitamin D3 analogue decreases cell number.
[Effect of human telomerase reverse transcriptase gene antisense oligonucleotide on sensitivity of gemcitabine in pancreatic cancer cell]
[Inhibition effects of phosphorothioate-modified antisense hTR on the telomerase activity and the growth of P3 cells derived from pancreatic cancer in culture]
[Specific activation of telomerase in pancreatic cancer tissue and preoperative diagnosis of pancreatic cancer by telomerase in pancreatic juice]
[Telomerase activity in pancreatic juice for the preoperative diagnosis of pancreatic cancer]
Pancreaticobiliary Maljunction
Telomerase activity and Bcl-2 expression in gallbladders of pancreaticobiliary maljunction patients: a preliminary study.
Pancreatitis
A highly sensitive and quantitative telomerase activity assay with pancreatic juice is useful for diagnosis of pancreatic carcinoma without problems due to polymerase chain reaction inhibitors: analysis of 100 samples of pancreatic juice from consecutive patients.
Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms.
Acute pancreatitis associated with different combination therapies in patients infected with human immunodeficiency virus.
Genetic diagnosis of pancreatic cancer using specimens obtained by EUS-FNA.
Genetic diagnosis of pancreatic cancer.
Incidence of acute pancreatitis and nucleoside reverse transcriptase inhibitors usage.
Incidence of pancreatitis in HIV-1-infected individuals enrolled in 20 adult AIDS clinical trials group studies: lessons learned.
Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs.
Interleukin 10 prevents necrosis in murine experimental acute pancreatitis.
Lactic acidosis in an HIV-infected patient receiving highly active antiretroviral therapy.
Long-term complications of nucleoside reverse transcriptase inhibitor therapy.
Managing issues related to antiretroviral therapy.
Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
Telomerase activity is detected in pancreatic cancer but not in benign tumors.
Telomerase elevation in pancreatic ductal carcinoma compared to nonmalignant pathological states.
[Specific activation of telomerase in pancreatic cancer tissue and preoperative diagnosis of pancreatic cancer by telomerase in pancreatic juice]
Pancreatitis, Chronic
Detection of K-ras point mutation and telomerase activity during endoscopic retrograde cholangiopancreatography in diagnosis of pancreatic cancer.
Detection of telomerase activity in patients with pancreatic cancer.
Diagnosis of pancreatic cancer by cytology and telomerase activity in exfoliated cells obtained by pancreatic duct brushing during endoscopy.
Diagnosis of pancreatic cancer by detecting telomerase activity in pancreatic juice: comparison with K-ras mutations.
Ex vivo expanded telomerase-specific T cells are effective in an orthotopic mouse model for pancreatic adenocarcinoma.
Real-time quantitative PCR of telomerase mRNA is useful for the differentiation of benign and malignant pancreatic disorders.
Telomerase activity as a marker for differential diagnosis of pancreatic adenocarcinoma: a systematic review and meta-analysis.
Telomerase activity in pancreatic juice differentiates pancreatic cancer from chronic pancreatitis: A meta-analysis.
Telomerase activity in periampullary tumors correlates with aggressive malignancy.
Telomerase activity in pure pancreatic juice for the diagnosis of pancreatic cancer may be complementary to K-ras mutation.
Pancytopenia
A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA.
[Clinical significance of telomerase activity detection of myeloid element in immune related hematocytopenia].
Papilloma
Absence or low number of telomere repeats at junctions of dicentric chromosomes.
An initiative to assess the quality of Tanzanian cervical cancer specimens for HPV and telomerase detection.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells.
Detention of HPV L1 Capsid Protein and hTERC Gene in Screening of Cervical Cancer.
Emerging antiviral drugs.
Equine telomeres and telomerase in cellular immortalisation and ageing.
Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancer.
Genetic analysis of myc and telomerase interactions in vivo.
High level expression of human epithelial beta-defensins (hBD-1, 2 and 3) in papillomavirus induced lesions.
Immortalization of Human Fetal Hepatocyte by Ectopic Expression of Human Telomerase Reverse Transcriptase, Human Papilloma Virus (E7) and Simian Virus 40 Large T (SV40 T) Antigen Towards Bioartificial Liver Support.
Increased telomerase activity in mouse skin premalignant progression.
Molecular cytogenetic analyses of hTERC (3q26) and MYC (8q24) genes amplifications in correlation with oncogenic human papillomavirus infection in Czech patients with cervical intraepithelial neoplasia and cervical carcinomas.
piggyBac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential.
Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
Senescence-Derived Extracellular Molecules as Modulators of Oral Cancer Development: A Mini-Review.
Serum-derived hepatitis C virus infectivity in interferon regulatory factor-7-suppressed human primary hepatocytes.
Synthesis, spectral characterization, DNA interaction, anticancer and molecular docking studies on some transition metal complexes with bidentate ligand.
Telomerase activity in human proliferative breast lesions.
Telomerase and cell proliferation in mouse skin papillomas.
Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6.
The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair.
The role of human telomerase catalytic subunit mRNA expression in cervical dysplasias.
Papilloma, Inverted
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Telomerase reverse transcriptase (TERT) promoter mutation analysis of benign, malignant and reactive urothelial lesions reveals a subpopulation of inverted papilloma with immortalizing genetic change.
Papillomavirus Infections
Approved Antiviral Drugs over the Past 50 Years.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Development of a condemned mucosa syndrome and pathogenesis of human papillomavirus-associated upper aerodigestive tract and uterine cervical tumors.
Expression of HPV-16 E6 Protein and p53 Inactivation Increases the Uterine Cervical Cancer Invasion.
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.
High expression of human telomerase reverse transcriptase in high-grade intraepithelial neoplasia and carcinoma of uterine cervix and its correlation with human papillomavirus infection.
HPV detection and measurement of HPV-16, telomerase, and survivin transcripts in colposcopy clinic patients.
Human telomerase gene amplification and high-risk human papillomavirus infection in women with cervical intra-epithelial neoplasia.
Human Telomerase Gene and High-Risk Human Papillomavirus Infection are Related to Cervical Intraepithelial Neoplasia.
Quantitative determination of human telomerase reverse transcriptase messenger RNA expression in premalignant cervical lesions and correlation with human papillomavirus load.
Relationship between the expression of telomerase and human papillomavirus infection in invasive uterine cervical carcinoma.
Telomerase activation and human papillomavirus infection in invasive uterine cervical carcinoma in a set of Malaysian patients.
Telomerase activity and expression of its RNA component in cervical lesions.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity in cervical smears.
Telomerase activity in condyloma acuminatum tissue with different HPV types.
Telomerase activity in HPV-associated vulvar vestibulitis.
Telomerase activity in Papanicolaou smear-negative exfoliated cervical cells and its association with lesions and oncogenic human papillomaviruses.
Telomerase Induction in HPV Infection and Oncogenesis.
Telomerase, cervical cancer, and human papillomavirus.
Telomerase, p53 and human papillomavirus infection in the uterine cervix.
The role of human telomerase catalytic subunit mRNA expression in cervical dysplasias.
Paraganglioma
Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma.
Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma.
Paralysis
Detection of enteroviruses by reverse-transcriptase polymerase chain reaction in cell culture negative stool specimens of patients with acute flaccid paralysis.
Paramyxoviridae Infections
Association of Human Metapneumovirus with Radiologically Diagnosed Community-Acquired Alveolar Pneumonia in Young Children.
The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children, 2000-2005.
[Parainfluenza virus type 4 infections]
Paraproteinemias
Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.
Expression Profile of Telomere-associated Genes in Multiple Myeloma.
Telomerase activity in plasma cell dyscrasias.
Parapsoriasis
Shortened telomere length is demonstrated in T-cell subsets together with a pronounced increased telomerase activity in CD4 positive T cells from blood of patients with mycosis fungoides and parapsoriasis.
Telomerase activity and telomere length in lymphocytes from patients with cutaneous T-cell lymphoma.
Parasitic Diseases
HIV Protease Inhibitors: Effect on the Opportunistic Protozoan Parasites.
Parathyroid Neoplasms
Azidothymidine induces apoptosis and inhibits cell growth and telomerase activity of human parathyroid cancer cells in culture.
Consistent decrease in telomere length in parathyroid tumors but alteration in telomerase activity limited to malignancies: preliminary report.
Demonstration of human telomerase reverse transcriptase (hTERT) in human parathyroid tumours by in situ hybridization with a new oligonucleotide probe.
Diagnosis of parathyroid carcinoma using immunohistochemical staining against hTERT.
Telomerase activation and expression of its catalytic subunits in benign and malignant tumors of the parathyroid.
Telomerase repeat amplification protocol (TRAP): A new molecular marker for parathyroid carcinoma.
Paratuberculosis
Mycobacterial cell wall components induce the production of TNF-alpha, IL-1, and IL-6 by bovine monocytes and the murine macrophage cell line RAW 264.7.
Parkinson Disease
Brain-derived Neurotrophic Factor Signaling Pathway: Modulation by Acupuncture in Telomerase Knockout Mice.
Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson's disease associated with enhanced autophagy.
The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America.
Pelvic Neoplasms
Telomerase activity in human urothelial tumors.
Peptic Ulcer
Clinical significance of telomerase activity in peritoneal lavage fluid from patients with gastric cancer and its relationship with cellular proliferation.
Detection of telomerase activity in gastric lavage fluid: a novel method to detect gastric cancer.
Peri-Implantitis
The pathology of bone tissue during peri-implantitis.
Periodontal Diseases
Evaluation of telomerase expression in chronic periodontitis.
Periodontitis
A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis.
Aggressive periodontitis: An appraisal of systemic effects on its etiology-genetic aspect.
Peripheral Nervous System Diseases
Activation of c-Jun N-terminal kinase mediates gp120IIIB- and nucleoside analogue-induced sensory neuron toxicity.
African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy.
Alcohol consumption enhances antiretroviral painful peripheral neuropathy by mitochondrial mechanisms.
Caspase signalling in neuropathic and inflammatory pain in the rat.
Clinical assessment of peripheral neuropathy in HIV-infected children on antiretroviral therapy in rural South Africa.
Genome-Wide Screen Identifies Drug-Induced Regulation of the Gene Giant Axonal Neuropathy (Gan) in a Mouse Model of Antiretroviral-Induced Painful Peripheral Neuropathy.
Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy.
High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment.
Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat.
Mitochondrial DNA levels in fat and blood cells from patients with lipodystrophy or peripheral neuropathy and the effect of 90 days of high-dose coenzyme Q treatment: a randomized, double-blind, placebo-controlled pilot study.
Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study.
Neurological and psychiatric adverse effects of antiretroviral drugs.
Neuropathic and neurocongnitive complications of antiretroviral therapy among HIV-infected patients.
Neuropsychiatric Effects of Antiviral Drugs.
Nucleoside reverse transcriptase inhibitor usage and the incidence of peripheral neuropathy in HIV/AIDS patients.
Oxidant stress and peripheral neuropathy during antiretroviral therapy: an AIDS clinical trials group study.
Peripheral neuropathy during stavudine-didanosine antiretroviral therapy.
Pharmacogenetics of nucleoside reverse-transcriptase inhibitor-associated peripheral neuropathy.
The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy.
The risk of developing peripheral neuropathy induced by nucleoside reverse transcriptase inhibitors decreases over time: evidence from the Delta trial.
Will pharmacogenomic discoveries improve HIV therapeutics?
Peritoneal Neoplasms
Telomerase assay for differentiating between malignancy-related and nonmalignant ascites.
Peritonitis
Whole blood cytokine profiles in cats infected by feline coronavirus and healthy non-FCoV infected specific pathogen-free cats.
Persistent Infection
Selective Serotonin Reuptake Inhibitor Suppression of HIV Infectivity and Replication.
Variant of hepatitis B virus with primary resistance to adefovir.
[The sensitivity of transmitted/founder HIV-1 to anti-HIV drugs].
Pharyngitis
Prevalence and clinical features of pneumonia in patients with laboratory-confirmed pandemic influenza A H1N1 2009 infection in South Korea.
Pheochromocytoma
A G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells.
A subcellular distribution of estrogen receptor-alpha is changed during artificially induced senescence of PC12 pheochromocytoma cells.
Anti-apoptotic role of telomerase in pheochromocytoma cells.
Differential expression of human telomerase catalytic subunit mRNA by in situ hybridization in pheochromocytomas.
Elevated levels of telomerase activity in malignant pheochromocytoma.
Expression of the human telomerase reverse transcriptase in pheochromocytoma and neuroblastoma tissues.
Glucagon does not affect catecholamine release in primary cultures of bovine adrenal chromaffin cells.
Histologically benign but telomerase positive adrenal pheochromocytoma.
HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma.
KI-67 AND hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma.
Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma.
Telomerase activity in adrenal cortical tumors and pheochromocytomas with reference to clinicopathologic features.
Telomerase activity in benign and malignant adrenal tumors.
Telomerase down-regulation does not mediate PC12 pheochromocytoma cell differentiation induced by NGF, but requires MAP kinase signalling.
Withdrawal. HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma.
[Markers of malignancy in pheochromocytomas]
Phyllodes Tumor
Droplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations.
Telomerase activity in human breast tumors.
Telomerase activity in phyllodes tumours.
Pituitary Diseases
Circulating microRNA as a biomarker of human growth hormone administration to patients.
Pituitary Neoplasms
Biomarkers of pituitary carcinomas.
Differential telomerase expression in human primary intracranial tumors.
Metabolic Reprogramming Drives Pituitary Tumor Growth through Epigenetic Regulation of TERT.
Plasma miR-185 as a predictive biomarker for prognosis of malignant glioma.
Prognostic implications of telomerase expression in pituitary adenomas.
Study of the telomerase hTERT fraction, PCNA and CD34 expression on pituitary adenomas. Association with clinical and demographic characteristics.
Telomerase activity and the expression of telomerase components in pituitary adenoma with malignant transformation.
Telomerase activity in pituitary adenomas: significance of telomerase expression in predicting pituitary adenoma recurrence.
Telomerase expression in clinically non-functioning pituitary adenomas.
Telomere length and telomerase expression in pituitary tumors.
Telomere length and TERT abnormalities in pituitary adenomas.
TERT Expression in Pituitary Adenomas.
The Relationship Between Phospho-p38, Matrix Metalloproteinase 9, and Major Histocompatibility Complex Class I Chain-Related Molecule A Expression in Pituitary Adenomas Demonstrates a New Mechanism of Pituitary Adenoma Immune Escape.
Placenta Previa
Increased Levels of Cell-Free Human Placental Lactogen mRNA at 28-32 Gestational Weeks in Plasma of Pregnant Women With Placenta Previa and Invasive Placenta.
Placental Insufficiency
Telomere homeostasis in IUGR placentas - A review.
Plasmacytoma
Interphase detection of t(4;14)(p16.3;q32.3) by in situ hybridization and FGFR3 overexpression in plasma cell malignancies.
Murine intracisternal type A particles: a biochemical characterization.
[Synthesis of double-stranded DNA on light immunoglobulin chain matrix RNA]
Pleural Effusion
Clinical significance of CYFRA21-1, Scc-Ag and telomerase activity in serum and pleural effusion of patients with squamous-cell lung cancer.
Comparison of telomerase activity between malignant and tuberculous pleural effusions.
Detection of telomerase activity in oral lesions.
Diagnostic implications of telomerase activity in pleural effusions.
Expression of matrix metalloproteinase-9 in pleural effusions of tuberculosis and lung cancer.
hTERT Gene Amplification and Clinical Significance in Pleural Effusions of Patients With Lung Cancer.
In situ telomerase activity in pleural effusions: a promising marker for malignancy.
Limitations of detection of malignancy in pleural effusions using ELISA-based TRAP assay: comparison with cytological examination.
Telomerase activity in pleural effusions: diagnostic significance.
Telomerase detection in body fluids.
Tissue-specific promoters active in CD44+CD24-/low breast cancer cells.
Tuberculin purified protein derivative up-regulates the telomerase activity of peripheral blood mononuclear cells from patients with pulmonary tuberculosis.
[Application of combined telomerase activity analysis and immunocytochemistry in cytopathologic diagnosis].
[Comparison of the diagnostic value of telomerase activity with CEA level in benign and malignant pleural effusions]
[Detection of telomerase activity in human lung cancer.]
[Detection of telomerase activity of exfoliated cells in bile and its clinical impact]
[Diagnostic significance of combining telomerase activity with CYFRA21-1 level in differentiating malignant pleural effusion caused by lung cancer from benign pleural effusion]
[Diagnotic value of the combined determination of telomerase activity in induced sputum, pleural effusion and fiberobronchoscopic biopsy samples in lung cancer]
Pleural Effusion, Malignant
Diagnosis and origin determination of malignant pleural effusions through the use of the breast cancer marker human mammaglobin.
Diagnostic accuracy of human telomerase reverse transcriptase mRNA in malignant pleural effusions: A preliminary report for in situ hybridization detection.
Diagnostic implications of telomerase activity in pleural effusions.
Telomerase activity assay for the diagnosis of malignant pleural effusion: A meta-analysis.
Telomerase activity in pleural effusions: diagnostic significance.
[Comparison of the diagnostic value of telomerase activity with CEA level in benign and malignant pleural effusions]
[Diagnostic significance of combining telomerase activity with CYFRA21-1 level in differentiating malignant pleural effusion caused by lung cancer from benign pleural effusion]
Pleurisy
Expression of telomerase reverse transcriptase (TERT) in malignant mesotheliomas.
Pneumonia
COVID-19 Carrier or Pneumonia: Positive Real-Time Reverse-Transcriptase Polymerase Chain Reaction but Negative or Positive Chest CT Results.
Diagnosis of Measles Pneumonia from Bronchoalveolar Lavage Fluid by Reverse-Transcriptase Polymerase Chain Reaction: Case Report.
Evidence for interference, coinfections, and intertypic virus enhancement of infection by ovine-caprine lentiviruses.
Human metapneumovirus associated with community-acquired pneumonia in children in Beijing, China.
Initial Clinical Management of Symptomatic Adult Patients during Influenza A (H1N1) Epidemics.
Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness.
Telomerase activity in peripheral blood mononuclear cells from senile patients with pneumonia.
The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications.
[Detection of telomerase activity in bronchoscopic brush-off cells in lung cancer patients]
[Diagnosis of adult measles pneumonia from bronchoalveolar lavage fluid by reverse-transcriptase polymerase chain reaction]
[Two patients with novel influenza A virus (H1N1) pneumonia treated with steroid therapy after an incorrect diagnosis of rapid progressive interstitial pneumonia due to the negative results of a rapid-antigen test].
Pneumonia, Progressive Interstitial, of Sheep
Differential levels of mRNAs for cytokines, the interleukin-2 receptor and class II DR/DQ genes in ovine interstitial pneumonia induced by maedi visna virus infection.
Pneumothorax
COVID-19 Complicated by Spontaneous Pneumothorax.
Telomerase mutations in smokers with severe emphysema.
poly(a)-specific ribonuclease deficiency
PARN modulates Y RNA stability, 3' end formation and its modification.
The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation.
Polycystic Kidney Diseases
Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Ca2+ signaling in human ADPKD cyst epithelial cells.
Polycystic Kidney, Autosomal Dominant
A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1.
Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Ca2+ signaling in human ADPKD cyst epithelial cells.
Expression and secretion of CXCL12 are enhanced in autosomal dominant polycystic kidney disease.
Polycystic Ovary Syndrome
Ovarian Telomerase and Female Fertility.
Telomere Length and Telomerase Activity in Immature Oocytes and Cumulus Cells of Women with Polycystic Ovary Syndrome.
Telomere length is short in PCOS and oral contraceptive does not affect the telomerase activity in granulosa cells of patients with PCOS.
Polycythemia Vera
Drug Development Pipeline for Myeloproliferative Neoplasms: Potential Future Impact on Guidelines and Management.
High telomerase activity in granulocytes from clonal polycythemia vera and essential thrombocythemia.
Particle-associated RNA dependent DNA polymerase and high-molecular-weight RNA in a human cell line derived from polycythemia vera bone marrow.
RNA-dependent DNA polymerase from a cell line derived from the bone marrow of a patient with polycythemia vera.
The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype.
[Analysis for telomerase activity in various hematologic disorders]
Polymyositis
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Polyneuropathies
Effect of Stavudine-Based Antiretroviral Therapy on the Severity of Polyneuropathy in HIV/AIDS Patients: A Preliminary Report From Zaria, Northern Nigeria.
Pharmacokinetics of Acetyl-L-Carnitine Given in Single or Multiple Doses to HIV-1 Infected Patients with Toxic Peripheral Polyneuropathy.
Polyradiculoneuropathy
Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies.
Porcine Reproductive and Respiratory Syndrome
Evaluation of the Risk of PRRSV Transmission via Ingestion of Muscle from Persistently Infected Pigs.
Human telomerase reverse transcriptase-immortalized porcine monomyeloid cell lines for the production of porcine reproductive and respiratory syndrome virus.
Poxviridae Infections
Emerging antiviral drugs.
Pre-Eclampsia
Comparative Analysis of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells between Preeclampsia and Normal Pregnant Women.
Localization of telomerase hTERT protein and survivin in placenta: relation to placental development and hydatidiform mole.
Precancerous Conditions
Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis.
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.
Telomerase Inhibition by Non-Nucleosidic Compound (BIBR1532) Causes Rapid Cell Death in Pre-B Acute Lymphoblastic Leukemia Cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase.
Clinical implications of telomerase activity levels in acute leukemia.
Correlation of telomerase activity to apoptosis and survival in adult acute lymphoblastic leukemia: an Egyptian single-center study.
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Does p16ink4a expression increase with the number of cell doublings in normal and malignant lymphocytes?
hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup.
Inhibition of telomerase using BIBR1532 enhances doxorubicin-induced apoptosis in pre-B acute lymphoblastic leukemia cells.
Methylation of CDKN2B CpG islands is associated with upregulated telomerase activity in children with acute lymphoblastic leukemia.
Quercetin-induced apoptosis involves increased hTERT enzyme activity of leukemic cells.
Role of neuropilin-1 and its expression in Egyptian acute myeloid and acute lymphoid leukemia patients.
TEL-AML1 fusion transcript in relapsed childhood acute lymphoblastic leukemia. The Berlin-Frankfurt-Münster Study Group.
Telomerase Inhibition by Non-Nucleosidic Compound (BIBR1532) Causes Rapid Cell Death in Pre-B Acute Lymphoblastic Leukemia Cells.
The p16(INK4A)/pRb pathway and telomerase activity define a subgroup of Ph+ adult Acute Lymphoblastic Leukemia associated with inferior outcome.
The telomerase inhibitor MST-312 synergistically enhances the apoptotic effect of doxorubicin in pre-B acute lymphoblastic leukemia cells.
[Isolation of a RNA-dependent DNA polymerase from lymphocytes of a cow suffering from lymphoblastic leukemia]
[The relationship between telomerase activity and cell cyele in acute leukemia cells]
Prediabetic State
Assessment of autonomic functions and its association with telomerase level, oxidative stress and inflammation in complete glycemic spectrum- an exploratory study.
Pistachio consumption modulates DNA oxidation and genes related to telomere maintenance: a crossover randomized clinical trial.
Pregnancy Complications
Telomerase activity in pregnancy complications (Review).
Preleukemia
Telomerase activity in preleukemia and acute myelogenous leukemia.
Premature Birth
Developmental delay and behavioral disorders in 59 HIV-exposed uninfected infants.
Telomere Length and Telomerase Activity in Foetal Membranes from Term and Spontaneous Preterm Births.
Primary Myelofibrosis
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
Characterization of In Vitro G-Quadruplex Formation of Imetelstat Telomerase Inhibitor.
Imetelstat, a telomerase inhibitor, is capable of depleting myelofibrosis stem and progenitor cells.
Quantitation of RNA-dependent platelet DNA polymerase in patients with myeloproliferative disorders.
Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis.
Telomerase Inhibitor Imetelstat in Essential Thrombocythemia and Myelofibrosis.
Telomeres and Telomerase in Hematopoietic Dysfunction: Prognostic Implications and Pharmacological Interventions.
Therapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromes.
Primary Ovarian Insufficiency
Impaired telomere length and telomerase activity in peripheral blood leukocytes and granulosa cells in patients with biochemical primary ovarian insufficiency.
Investigation of the role of serum telomerase levels in patients with occult primary ovarian insufficiency: a prospective cross-sectional study.
Ovarian Telomerase and Female Fertility.
Telomerase activity in normal ovaries and premature ovarian failure.
Telomere length in granulosa cells and leukocytes: a potential marker of female fertility? A systematic review of the literature.
Prion Diseases
Identification of disease markers by differential display: prion disease.
Progeria
Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome.
Fibroblast clones from patients with Hutchinson-Gilford progeria can senesce despite the presence of telomerase.
Telomerase mRNA Reverses Senescence in Progeria Cells.
Telomerase therapy reverses vascular senescence and extends lifespan in progeria mice.
Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.
[Priorities in fundamental research in gerontology: Russia contribution]
Prostatic Diseases
Detection of telomerase activity in human prostate: a diagnostic marker for prostatic cancer?
Prostatic Hyperplasia
An appraisal of telomerase activity in benign prostatic hyperplasia.
Association of TERT gene polymorphisms with clinical benign prostatic hyperplasia in a Chinese Han population of the Northwest region.
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Detection of telomerase activity in human prostate: a diagnostic marker for prostatic cancer?
Detection of telomerase activity in prostate massage samples improves differentiating prostate cancer from benign prostatic hyperplasia.
Human telomerase reverse transcriptase expression correlates with vascular endothelial growth factor-promoted tumor cell proliferation in prostate cancer.
Noninvasive detection of prostate cancer by quantitative analysis of telomerase activity.
Oncornavirus-like particles released by human prostatic explant cultures.
Patients with benign prostatic hyperplasia show shorter leukocyte telomere length but no association with telomerase gene polymorphisms in Han Chinese males.
Telomerase Activity and Telomere Length in Human Benign Prostatic Hyperplasia Stem-like Cells and Their Progeny Implies the Existence of Distinct Basal and Luminal Cell Lineages.
Telomerase activity in needle biopsies from prostate cancer and benign prostates.
Telomerase activity in primary prostate cancer.
Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium.
Telomerase as a new target for the treatment of hormone-refractory prostate cancer.
Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component.
[Prostate-specific antigen and telomerase in prostatic cancers]
Prostatic Intraepithelial Neoplasia
Cancer telomeres and white crows.
Expression of the RNA component of human telomerase (hTR) in prostate cancer, prostatic intraepithelial neoplasia, and normal prostate tissue.
Expression-patterns of the RNA component (hTR)and the catalytic subunit (hTERT) of human telomerase in nonneoplastic prostate tissue, prostatic intraepithelial neoplasia, and prostate cancer.
Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas.
Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium.
Telomerase activity in touch-imprint cell preparations from fresh prostate needle biopsy specimens.
Telomerase activity, telomere length, and DNA ploidy in prostatic intraepithelial neoplasia (PIN).
Telomerase as a tumor marker in diagnosis of prostatic intraepithelial neoplasia and prostate cancer.
Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology.
[Detection of telomerase activity in prostate needle-biopsy samples]
[Prostate-specific antigen and telomerase in prostatic cancers]
Prostatic Neoplasms
1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents.
A comparison of proteomic profiles changes during 17beta-estradiol treatment in human prostate cancer PC-3 cell line.
A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells.
A novel human cancer culture model for the study of prostate cancer.
A novel human cell culture model for the study of familial prostate cancer.
A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.
A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes.
A Triad of Telomerase, Androgen Receptor and Early Growth Response 1 in Prostate Cancer Cells.
Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line.
Androgen depletion activates telomerase in the prostate of the nonhuman primate, Macaca mulatta.
Antiproliferative effects of the histone deacetylase inhibitor FR901228 on small-cell lung cancer lines and drug-resistant sublines.
Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells.
Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors.
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness.
Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus.
BCG effects on telomerase activity in bladder cancer cell lines.
BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage.
Butyrate histone deacetylase inhibitors.
Cancer telomeres and white crows.
Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: a phase III metastatic castration resistant prostate cancer trial.
Combination treatment with 1alpha,25-dihydroxyvitamin D3 and 9-cis-retinoic acid directly inhibits human telomerase reverse transcriptase transcription in prostate cancer cells.
Combining a targeted radiotherapy and gene therapy approach for adenocarcinoma of prostate.
Comparison of telomerase activity and GSTP1 promoter methylation in ejaculate as potential screening tests for prostate cancer.
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Conversion of nested reverse-transcriptase polymerase chain reaction from positive to negative status at peripheral blood during androgen ablation therapy is associated with long progression-free survival in stage D2 prostate cancer patients.
Cytotoxic T cell immunity against telomerase reverse transcriptase in humans.
DD3(PCA3), a very sensitive and specific marker to detect prostate tumors.
Demethylating reagent 5-azacytidine inhibits telomerase activity in human prostate cancer cells through transcriptional repression of hTERT.
Designed modulation of sex steroid signaling inhibits telomerase activity and proliferation of human prostate cancer cells.
Detection of circulating tumor cells in patients with localized and metastatic prostatic carcinoma: clinical implications.
Detection of telomerase activity in human prostate: a diagnostic marker for prostatic cancer?
Detection of telomerase activity in prostate cancer by needle biopsy.
Detection of telomerase activity in prostate massage samples improves differentiating prostate cancer from benign prostatic hyperplasia.
Detection of telomerase activity in prostate needle-biopsy samples.
Detection of telomerase activity in prostatic fluid specimens.
Determination of the enzyme telomerase in needle biopsies and fine needle aspiration cytology samples of the prostate in the diagnosis of prostate cancer.
Diagnosing the miR-141 prostate cancer biomarker using nucleic acid-functionalized CdSe/ZnS QDs and telomerase.
Differences in the expression of telomerase and prostate-specific membrane antigen in non-advanced prostatic cancer.
Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells.
Disodium pentaborate decahydrate (DPD) induced apoptosis by decreasing hTERT enzyme activity and disrupting F-actin organization of prostate cancer cells.
Disruption of an hTERT-mTOR-RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin.
Down-regulation of human telomerase reverse transcriptase through specific activation of RNAi pathway quickly results in cancer cell growth impairment.
Effect of Achillea wilhelmsii extract on expression of the human telomerase reverse transcriptase mRNA in the PC3 prostate cancer cell line.
Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study.
Effects of androgens on telomerase activity in normal and malignant prostate cells in vitro.
Emerging immunotherapeutic strategies targeting telomerases in genitourinary tumors.
ETS family-associated gene fusions in Japanese prostate cancer: analysis of 194 radical prostatectomy samples.
Evaluation of PCR-ELISA for determination of telomerase activity in prostate needle biopsy and prostatic fluid specimens.
Expression of c-kit and kit-ligand in benign and malignant prostatic tissues.
Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation.
Expression of the RNA component of human telomerase (hTR) in prostate cancer, prostatic intraepithelial neoplasia, and normal prostate tissue.
Expression profile and prognostic importance in prostate lesions of the reverse transcriptase component of human telomerase (hTERT) and of cyclin-dependent kinase inhibitor p57 (p57(kip2a)).
Expression-patterns of the RNA component (hTR)and the catalytic subunit (hTERT) of human telomerase in nonneoplastic prostate tissue, prostatic intraepithelial neoplasia, and prostate cancer.
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.
Focal intratumoral heterogeneity for telomerase activity in human prostate cancer.
Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity.
Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells.
Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells.
High detection rate of circulating tumor cells in blood of patients with prostate cancer using telomerase activity.
Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells.
Human telomerase reverse transcriptase antisense treatment downregulates the viability of prostate cancer cells in vitro.
Human telomerase reverse transcriptase expression correlates with vascular endothelial growth factor-promoted tumor cell proliferation in prostate cancer.
Identification of bone marrow micrometastases in patients with prostate cancer.
In vivo regulation of hTERT expression and telomerase activity by androgen.
Indole-3-carbinol inhibits telomerase activity and gene expression in prostate cancer cell lines.
Inhibition of telomerase activity and secretion of prostate specific antigen by silibinin in prostate cancer cells.
Inhibition of telomerase by 2'-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells.
Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells.
Inhibition of telomerase potentiates enzalutamide efficiency of androgen-sensitive human prostate cancer cells.
Inhibition of telomerase with human telomerase reverse transcriptase antisense increases the sensitivity of tumor necrosis factor-alpha-induced apoptosis in prostate cancer cells.
Inositol hexaphosphate represses telomerase activity and translocates TERT from the nucleus in mouse and human prostate cancer cells via the deactivation of Akt and PKCalpha.
Insulin-like growth factor I stimulates telomerase activity in prostate cancer cells.
LNCaP prostate cancer cells are insensitive to zinc-induced senescence.
Low p16(INK4a) Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone.
Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles.
MNS16A tandem repeat minisatellite of human telomerase gene: functional studies in colorectal, lung and prostate cancer.
MNS16A tandem repeats minisatellite of human telomerase gene and prostate cancer susceptibility.
Modulation of telomerase activity by zinc in human prostatic and renal cancer cells.
Molecular staging of pelvic surgical margins after radical prostatectomy: comparison of RT-PCR for prostate-specific antigen and telomerase activity.
MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.
Noninvasive detection of prostate cancer by quantitative analysis of telomerase activity.
Novel stimulatory role for insulin-like growth factor binding protein-2 in prostate cancer cells.
Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells.
Overexpression of telomerase-associated chaperone proteins in prostatic intraepithelial neoplasia and carcinomas.
Phenotypic characterization of telomerase-immortalized primary non-malignant and malignant tumor-derived human prostate epithelial cell lines.
Phosphorylation status of Fas-associated death domain-containing protein regulates telomerase activity and strongly correlates with prostate cancer outcomes.
Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase.
Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells.
Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3.
Presence of circulating prostate cells in the bone marrow of patients undergoing radical prostatectomy is predictive of disease-free survival.
Prognostic Significance of Serum PSA Level and Telomerase, VEGF and GLUT-1 Protein Expression for the Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy.
Prostate cancer stem cells, telomerase biology, epigenetic modifiers, and molecular systemic therapy for the androgen-independent lethal phenotype.
Prostate tumor cells with cancer progenitor properties have high telomerase activity and are rapidly killed by telomerase interference.
Prostate tumor-initiating cells: A new target for telomerase inhibition therapy?
Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection.
Real-time quantification of human telomerase reverse transcriptase mRNA in the plasma of patients with prostate cancer.
Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide.
Relative contribution of normal and neoplastic cells determines telomerase activity and telomere length in primary cancers of the prostate, colon, and sarcoma.
Research into molecular and genetic mechanisms underlying prostate carcinogenesis would be greatly advanced by in vitro prostate cell models.
Role of telomerase in anticancer activity of pristimerin in prostate cancer cells.
Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells.
Signaling through estrogen receptors modulates telomerase activity in human prostate cancer.
SLX4IP N-terminus dictates telomeric localization in ALT-like castration-resistant prostate cancer cell lines.
Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model.
Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.
Superiority of an Asymmetric Perylene Diimide in Terms of Hydrosolubility, G-Quadruplex Binding, Cellular Uptake, and Telomerase Inhibition in Prostate Cancer Cells.
Suppression of telomerase, reexpression of KAI1, and abrogation of tumorigenicity by nerve growth factor in prostate cancer cell lines.
Targeted BikDD expression kills androgen-dependent and castration-resistant prostate cancer cells.
Targeting protein kinase C (PKC) and telomerase by phenethyl isothiocyanate (PEITC) sensitizes PC-3 cells towards chemotherapeutic drug-induced apoptosis.
Telomerase activity and telomerase subunit gene expression levels are not related in prostate cancer: a real-time quantification and in situ hybridization study.
Telomerase activity in disseminated prostate cancer cells.
Telomerase activity in needle biopsies from prostate cancer and benign prostates.
Telomerase activity in needle biopsies from prostate cancer and benign prostates: the influence of sampling bias.
Telomerase activity in primary prostate cancer.
Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium.
Telomerase activity in prostate sextant needle cores from radical prostatectomy specimens.
Telomerase activity modulation in the prevention of prostate cancer.
Telomerase activity, Myc and Bcl-2: possible indicators of effective therapy of prostate cancer with 9-nitrocamptothecin.
Telomerase activity: a prevalent marker of malignant human prostate tissue.
Telomerase as a new target for the treatment of hormone-refractory prostate cancer.
Telomerase as a tumor marker in diagnosis of prostatic intraepithelial neoplasia and prostate cancer.
Telomerase as an important target of androgen signaling blockade for prostate cancer treatment.
Telomerase enzyme inhibition (TEI) and cytolytic therapy in the management of androgen independent osseous metastatic prostate cancer.
Telomerase expression as a marker in prostate cancer: correlation to clinicopathologic predictors.
Telomerase Inhibition, Telomere Shortening, and Cellular Uptake of the Perylene Derivatives PM2 and PIPER in Prostate Cancer Cells.
Telomerase mRNA detection in serum of patients with prostate cancer.
Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer.
Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer.
Telomere DNA Damage Signaling Regulates Prostate Cancer Tumorigenesis.
Telomere length and telomerase activity in bladder and prostate cancer cell lines.
Telomere length influences cancer cell differentiation in vivo.
Telomeres and telomerase in prostate cancer development and therapy.
Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology.
Telomeric DNA: marker for human prostate cancer development?
TERT polymorphisms rs2853669 and rs7726159 influence on prostate cancer risk in Russian population.
The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP.
The effects on hTERT gene expression is an additional mechanism of amino-bisphosphonates in prostatic cancer cells.
The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
The potential utility of telomere-related markers for cancer diagnosis.
The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.
The synthetic estrogen diethylstilbestrol (DES) inhibits the telomerase activity and gene expression of prostate cancer cells.
The use of telomerase activity for the detection of prostatic cancer cells after prostatic massage.
Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component.
Tumor specific cytotoxicity and telomerase down-regulation in prostate cancer by autologous dendritic cells loaded with whole tumor cell antigens.
Value of the preoperative detection of prostate-specific-antigen-positive circulating cells by nested RT-PCR in patients submitted to radical prostatectomy.
Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development.
[Clinical significance of serum telomerase mRNA in patients with prostate cancer].
[Detection of telomerase activity in prostate needle-biopsy samples]
[Expressions of telomerase reverse transcriptase and vascular endothelial growth factor and their correlation in prostate cancer]
[Inhibition of telomerase with hTERT antisense enhances TNF-alpha-induced apoptosis in prostate cancer cells PC3]
[Prostate-specific antigen and telomerase in prostatic cancers]
[Telomerase activity in association with the pathological differentiation of prostate cancer]
[Telomerase activity in prostate cancer]
[The animal research of recombinant adenovirus controlled by human telomerase reverse transcriptase promoter in the treatment of human prostate cancer]
Psoriasis
Detection of telomerase activity in psoriasis lesional skin and correlation with Ki-67 expression and suppression by retinoic acid.
Expression of telomerase reverse transcriptase in psoriatic lesional skin.
In situ hybridization analysis of the expression of human telomerase RNA in normal and pathologic conditions of the skin.
Telomerase activity is increased and telomere length shortened in T cells from blood of patients with atopic dermatitis and psoriasis.
Pterygium
Relative gene expression analysis of human pterygium tissues and UV radiation-evoked gene expression patterns in corneal and conjunctival cells.
Telomerase activity and p53 expression in pterygia.
Telomerase activity in pterygeal and normal conjunctival epithelium.
Pulmonary Alveolar Proteinosis
Pulmonary alveolar proteinosis revealing a telomerase disease.
Pulmonary Disease, Chronic Obstructive
Association between Telomere-Related Polymorphisms and the Risk of IPF and COPD as a Precursor Lesion of Lung Cancer: Findings from the Fukuoka Tobacco-Related Lung Disease (FOLD) Registry.
Long-term tobacco exposure and immunosenescence: Paradoxical effects on T-cells telomere length and telomerase activity.
Mild catalytic defects of tert rs61748181 polymorphism affect the clinical presentation of chronic obstructive pulmonary disease.
miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar Macrophages.
Serum Telomerase Levels and COPD Exacerbations.
Significance of viral infections detected by reverse-transcriptase - multiplex PCR on hospital-related outcomes in acute exacerbations of chronic obstructive pulmonary disease.
Telomerase mutations in smokers with severe emphysema.
TERT gene polymorphisms are associated with chronic obstructive pulmonary disease risk in the Chinese Li population.
Pulmonary Edema
Shorter telomere length, higher telomerase activity in association with Tankyrase gene Polymorphism contribute to High-altitude pulmonary edema.
Pulmonary Emphysema
Differing Expression of Cytokines and Tumor Markers in Combined Pulmonary Fibrosis and Emphysema Compared to Emphysema and Pulmonary Fibrosis.
Pulmonary Fibrosis
A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.
A spectrum of severe familial liver disorders associate with telomerase mutations.
AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
Acute graft-versus-host disease following lung transplantation in a patient with a novel
Adult-onset pulmonary fibrosis caused by mutations in telomerase.
Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis.
Bone Marrow CD11c+ Cell-Derived Amphiregulin Promotes Pulmonary Fibrosis.
Bone marrow failure and the telomeropathies.
Clinical outcomes of lung transplant recipients with telomerase mutations.
Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis.
Constitutional telomerase mutations are genetic risk factors for cirrhosis.
Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference.
Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations.
Erratum: Parry EM, Alder JK, Qi X, Chen JJ-L, Armanios M. Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase. Blood. 2011;117(21):5607-5611.
Exome sequencing identifies mutant TINF2 in a family with pulmonary fibrosis.
Familial pulmonary fibrosis.
Genetic Basis of Children's Interstitial Lung Disease.
Genetic predisposition to respiratory diseases: infiltrative lung diseases.
Heterozygous RTEL1 mutations are associated with familial pulmonary fibrosis.
Induction of telomerase activity in fibroblasts from bleomycin-injured lungs.
InTERTpreting telomerase structure and function.
Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.
Liver Transplantation for Decompensated Cirrhosis Secondary to Telomerase Reverse Transcriptase (TERT) Mutation.
Liver transplantation for hepatocellular carcinoma in a patient with a novel telomerase mutation and steatosis.
Lung transplantation in telomerase mutation carriers with pulmonary fibrosis.
Many disease-associated variants of hTERT retain high telomerase enzymatic activity.
Natural History of Pulmonary Fibrosis in Two Subjects with the Same Telomerase Mutation.
New trajectories in the treatment of interstitial lung disease: treat the disease or treat the underlying pattern?
Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of TERT.
Prevalence and characteristics of TERT and TERC mutations in suspected genetic pulmonary fibrosis.
Pulmonary fibrosis, bone marrow failure, and telomerase mutation.
Recent progress in dyskeratosis congenita.
Regulation of telomerase activity in rat lung fibroblasts.
Reply: Telomerase Makes Connections between Pulmonary Fibrosis and Emphysema.
Severe hematologic complications after lung transplantation in patients with telomerase complex mutations.
Short telomeres in pulmonary fibrosis: from genetics to clinical significance.
Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells.
Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase.
Synonymous Mutation in DKC1 Causes Telomerase RNA Insufficiency Manifesting as Familial Pulmonary Fibrosis.
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.
Telomerase and idiopathic pulmonary fibrosis.
Telomerase and Telomere Length in Pulmonary Fibrosis.
Telomerase mutations in families with idiopathic pulmonary fibrosis.
Telomerase mutations in smokers with severe emphysema.
Telomerase RNA biosynthesis and processing.
Telomerase, myofibroblasts, and pulmonary fibrosis.
Telomerase-related monogenic lung fibrosis presenting with subacute onset: a case report and review of literature.
Telomere Abnormalities in the Pathobiology of Idiopathic Pulmonary Fibrosis.
Telomere dynamics in mice and humans.
Telomere length in patients with pulmonary fibrosis associated with chronic lung allograft dysfunction and post-lung transplantation survival.
Telomere Length is a Determinant of Emphysema Susceptibility.
Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations.
Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease.
Telomere shortening in familial and sporadic pulmonary fibrosis.
Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.
Telomeres and disease.
Telomeres in lung diseases.
Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres.
Understanding telomere diseases through analysis of patient-derived iPS cells.
ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation.
Purpura, Thrombocytopenic, Idiopathic
Methylation of CDKN2B CpG islands is associated with upregulated telomerase activity in children with acute lymphoblastic leukemia.
Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow.
Telomerase activity increased and telomere length shortened in peripheral blood cells from patients with immune thrombocytopenia.
Pyuria
Semi-quantitative analysis of telomerase activity of exfoliated cells in urine of patients with urothelial cancers: Causative factors affecting sensitivity and specificity.
[Molecular biological testing for diagnosis and treatment of urothelial cancer]
Rabies
Antibodies to rabies virus in terrestrial wild mammals in native rainforest on the north coast of São Paulo State, Brazil.
Epidemiology of rabies in Southeast Europe.
Heminested reverse-transcriptase polymerase chain reaction (hnRT-PCR) as a tool for rabies virus detection in stored and decomposed samples.
Molecular approach for ante-mortem diagnosis of rabies in dogs.
Rabies in the arctic fox population, Svalbard, Norway.
Rabies situation in Cambodia.
Rapid identification of the raccoon rabies virus variant using a real-time reverse-transcriptase polymerase chain reaction.
Re-assessment of direct fluorescent antibody negative brain tissues with a real-time PCR assay to detect the presence of raccoon rabies virus RNA.
Use of reverse transcription-polymerase chain reaction to determine the stability of rabies virus genome in brains kept at room temperature.
[A human rabies case with antemortem diagnosis]
[Significance of modern methods for laboratory detection of rabies agents and identification of the zoonose immunological survey].
Rectal Neoplasms
Author Correction: The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients.
Change of telomerase activity in rectal cancer with chemoradiation therapy.
Differences in telomerase activity between colon and rectal cancer.
Expression pattern of telomerase reverse transcriptase in rectal carcinoma predicts tumor radiosensitivity, local recurrence and disease-free survival.
Novel Prognostic Biomarkers in Metastatic and Locally Advanced Colorectal Cancer: Micronuclei Frequency and Telomerase Activity in Peripheral Blood Lymphocytes.
Telomerase activity is a prognostic factor for recurrence and survival in rectal cancer.
Telomerase expression as a predictive marker of radiotherapy response in rectal cancer.
The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients.
Relative Energy Deficiency in Sport
Comparative Biological Properties and Mineralization Potential of 3 Endodontic Materials for Vital Pulp Therapy: Theracal PT, Theracal LC, and Biodentine on Human Dental Pulp Stem Cells.
Effect of iRoot Fast Set root repair material on the proliferation, migration and differentiation of human dental pulp stem cells in vitro.
Highly osteogenic PDL stem cell clones specifically express elevated levels of ICAM1, ITGB1 and TERT.
Renal Insufficiency
Is there a connection between inflammation, telomerase activity and the transcriptional status of telomerase reverse transcriptase in renal failure?
Renal Insufficiency, Chronic
Telomerase activity in patients with stage 2-5D chronic kidney disease.
Telomeres and telomerase in renal health.
Reoviridae Infections
Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts.
Reperfusion Injury
Effects of hUCB-MSCs on recovery of neurological function and TERT expression in brain tissue of rats with cerebral ischemia-reperfusion injury.
Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity.
Protection against ischemia-reperfusion injury in aged liver donor by the induction of exogenous human telomerase reverse transcriptase gene.
Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy.
Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury.
Respiratory Syncytial Virus Infections
Approved Antiviral Drugs over the Past 50 Years.
Respiratory Tract Infections
Clinical outcomes of lung transplant recipients with telomerase mutations.
Epidemiological investigation of nine respiratory pathogens in hospitalized children in Germany using multiplex reverse-transcriptase polymerase chain reaction.
Frequent detection of human coronaviruses in clinical specimens from patients with respiratory tract infection by use of a novel real-time reverse-transcriptase polymerase chain reaction.
Patterns of Influenza Vaccination and Vaccine Effectiveness Among Young US Children Who Receive Outpatient Care for Acute Respiratory Tract Illness.
Viral etiology of respiratory infections in children in southwestern Saudi Arabia using multiplex reverse-transcriptase polymerase chain reaction.
Retinal Degeneration
Protection of Retinal Function by Nucleoside Reverse Transcriptase Inhibitors Following Retinal Ischemia/Reperfusion Injury.
Retinal Neovascularization
Expression profile and regulation of telomerase reverse transcriptase on oxygen-induced retinal neovascularization.
Retinoblastoma
A genetically defined model for human ovarian cancer.
Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability.
Activation of telomerase rna gene promoter activity by NF-Y, Sp1, and the retinoblastoma protein and repression by Sp3.
Association between telomerase activity and basic fibroblast growth factor up-regulation in retinoblastomas.
Correction: Disruption of the retinoblastoma pathway by small interfering RNA and ectopic expression of the catalytic subunit of telomerase lead to immortalization of human ovarian surface epithelial cells.
Detection of mutations in the RB1 gene by single strand conformation polymorphism (SSCP) analysis, amplification mismatch detection (AMD) analysis and polymerase chain reaction sequencing.
Development of retinoblastoma in the absence of telomerase activity.
Disruption of the retinoblastoma pathway by small interfering RNA and ectopic expression of the catalytic subunit of telomerase lead to immortalization of human ovarian surface epithelial cells.
Establishment of an immortal chicken embryo liver-derived cell line.
Growth arrest of immortalized human keratinocytes and suppression of telomerase activity by p21WAF1 gene expression.
Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1.
Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer.
Intact functional domains of the retinoblastoma gene product (pRb) are required for downregulation of telomerase activity.
Involvement of RB-1, p53, p16INK4 and telomerase in immortalisation of human cells.
Molecular and genetic aspects of odontogenic tumors: a review.
NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.
Order of genetic events is critical determinant of aberrations in chromosome count and structure.
Prognostic factors in stage I/II non-small cell lung cancer.
Rb and E2F-1 regulate telomerase activity in human cancer cells.
Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition.
Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin.
Telomerase activation as a repair response to radiation-induced DNA damage in Y79 retinoblastoma cells.
Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites.
Telomerase activity is associated with cell cycle deregulation in human breast cancer.
Telomerase regulation, cell cycle, and telomere stability in primitive hematopoietic cells.
The Human Cytomegalovirus Strain DB Activates Oncogenic Pathways in Mammary Epithelial Cells.
The oncolytic adenovirus targeting to TERT and RB pathway induced specific and potent anti-tumor efficacy in vitro and in vivo for hepatocellular carcinoma.
The Over-Expression of E2F3 Might Serve as Prognostic Marker for Neuroblastoma Patients with Stage 4S Disease.
The tumor cell and telomerase.
USP22 down-regulation facilitates human retinoblastoma cell aging and apoptosis via inhibiting TERT/P53 pathway.
Vitamin D analogs, a new treatment for retinoblastoma: The first Ellsworth Lecture.
[Experimental study on effect of epimedium flavonoids in protecting telomere length of senescence cells HU]
[The effects of matrine on cell proliferation and telomerase activity in retinoblastoma cells in vitro]
[The study on the correlation between telomerase and histopathologic features of retinoblastoma]
Retroviridae Infections
Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors.
[Establishment and application of oncogene over expressed human epithelial cell transformation model]
Rhabdoid Tumor
Effect of telomerase inhibition on preclinical models of malignant rhabdoid tumor.
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
Rhabdomyolysis
Severe myositis on commencement of efavirenz, abacavir and lamivudine, in the absence of lactic acidosis or classical abacavir hypersensitivity.
Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART).
Rhabdomyosarcoma
Characterization of multiple molecular interactions between human cytomegalovirus (HCMV) and human immunodeficiency virus type 1 (HIV-1).
Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma.
Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma.
Genetic modeling of Ras-induced human rhabdomyosarcoma.
Telomerase Activation in Malignant Bone Tumors.
Telomerase reverse transcriptase promoter regulation during myogenic differentiation of human RD rhabdomyosarcoma cells.
Rhabdomyosarcoma, Alveolar
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
RT-PCR evaluation of peripheral blood, bone marrow and peripheral blood stem cells in children and adolescents undergoing VACIME chemotherapy for Ewing's sarcoma and alveolar rhabdomyosarcoma.
Rhabdomyosarcoma, Embryonal
Telomerase activity in cell lines of pediatric soft tissue sarcomas.
Rheumatic Diseases
Telomerase activity in the synovial tissues of chronic inflammatory and non-inflammatory rheumatic diseases.
Rhinitis, Allergic, Seasonal
Nasal messenger RNA expression of interleukins 2, 4, and 5 in patients with allergic rhinitis.
rna-directed dna polymerase deficiency
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance.
A method for efficient quantitative analysis of genomic subtelomere Y' element abundance in yeasts.
A Newfoundland cohort of familial and sporadic idiopathic pulmonary fibrosis patients: clinical and genetic features.
A possible role for telomerase RNA and telomere length in global mitotic recombination.
Aberrant gene expression profiles, during in vitro osteoblast differentiation, of telomerase deficient mouse bone marrow stromal stem cells (mBMSCs).
An enhanced H/ACA RNP assembly mechanism for human telomerase RNA.
An essential role for functional telomeres in mouse germ cells during fertilization and early development.
An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres.
Bone Marrow Stromal Cell (BMSC) and skeletal aging: Role of telomerase enzyme.
Brain-derived Neurotrophic Factor Signaling Pathway: Modulation by Acupuncture in Telomerase Knockout Mice.
Clonal cell populations unresponsive to radiosensitization induced by telomerase inhibition.
Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes.
Correction to: Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes.
Cytogenetic Analysis of Telomere Dysfunction.
Defective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects.
Defects in lymphocyte telomere homeostasis contribute to cellular immune phenotype in patients with cartilage-hair hypoplasia.
Deficiency of colonic telomerase in ulcerative colitis.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in hoyeraal-hreidarsson syndrome.
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndrome.
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres.
DNA synthesis generates terminal duplications that seal end-to-end chromosome fusions.
DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.
Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer.
Dyskeratosis congenita: a genetic disorder of many faces.
Dyskeratosis congenita: molecular insights into telomerase function, ageing and cancer.
Engineered telomere degradation models dyskeratosis congenita.
Familial myelodysplastic syndromes - a review of the literature.
Genetic analysis of myc and telomerase interactions in vivo.
Heterozygous telomerase deficiency in mouse and man: when less is definitely not more.
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
Interstitial lung disease in the elderly: pathogenesis, diagnosis and management.
Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.
ISH ADA-01 Critical role of telomerase in regulating cerebral vascular function and redox environment.
Limbal stem cell deficiency in patients with inherited stem cell disorder of dyskeratosis congenita.
Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production.
Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche.
Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid.
PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres.
Pathogenic TERT promoter variants in telomere diseases.
Pathophysiologic mechanisms in acquired aplastic anemia.
Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.
Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.
Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles.
Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.
Robust DNA Damage Response and Elevated Reactive Oxygen Species in TINF2-Mutated Dyskeratosis Congenita Cells.
Role of telomerase in hematopoietic stem cells.
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing.
Specificity and Stoichiometry of Subunit Interactions in the Human Telomerase Holoenzyme Assembled In vivo.
Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme.
Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis.
Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway.
Telomerase Deficiency Affects Normal Brain Functions in Mice.
Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae.
Telomerase deficiency and cancer susceptibility syndromes.
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene.
Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.
Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy.
Telomerase deficiency does not alter bleomycin-induced fibrosis in mice.
Telomerase deficiency impairs differentiation of mesenchymal stem cells.
Telomerase deficiency impairs glucose metabolism and insulin secretion.
Telomerase deficiency in a colonial ascidian after prolonged asexual propagation.
Telomerase deficiency in bone marrow-derived cells attenuates angiotensin II-induced abdominal aortic aneurysm formation.
Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury.
Telomerase deficiency promotes oxidative stress by reducing catalase activity.
Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.
Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice.
Telomerase in the human organism.
Telomerase is required for zebrafish lifespan.
Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases.
Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes.
Telomerase reverse-transcriptase homozygous mutations in autosomal recessive dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome.
Telomerase RNA deficiency in peripheral blood mononuclear cells in X-linked dyskeratosis congenita.
Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita.
Telomerase-deficient mice exhibit bone loss due to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.
Telomere dynamics in genome stability.
Telomere dynamics in mice and humans.
Telomere dysfunction reduces microglial numbers without fully inducing an aging phenotype.
Telomere dysfunction, autoimmunity and aging.
Telomere Length is a Determinant of Emphysema Susceptibility.
Telomeres and disease.
Telomeres in aging and disease: lessons from zebrafish.
Telomeres in hematopoietic stem cells.
TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B[a]P in vivo.
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres.
The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.
The mTOR pathway is necessary for survival of mice with short telomeres.
The role of telomerase expression and telomere length maintenance in human and mouse.
Ulcerative Typhlocolitis Associated With Helicobacter mastomyrinus in Telomerase-Deficient Mice.
When Telomerase Causes Telomere Loss.
Zebrafish models for dyskeratosis congenita reveal critical roles of p53 activation contributing to hematopoietic defects through RNA processing.
[ALT--alternative lengthening of telomere]
Sarcoidosis
Telomerase activity in sputum and telomerase and its components in biopsies of advanced lung cancer.
Sarcoma
A comparative evaluation of methods for isolation of RNA-directed DNA polymerase from cells in a reconstituted system.
Absence of telomerase activity in malignant bone tumors and soft-tissue sarcomas.
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.
Analysis of telomerase activity and telomere length in bone and soft tissue tumors.
Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines.
Bone and Soft-Tissue Sarcoma: A New Target for Telomerase-Specific Oncolytic Virotherapy.
Chromosomal disruption and rearrangements during murine sarcoma development converge to stable karyotypic formation kept by telomerase overexpression.
Co-expression of survivin and TERT and risk of tumour-related death in patients with soft-tissue sarcoma.
Complete remission of AIDS/Kaposi's sarcoma after treatment with a combination of two nucleoside reverse transcriptase inhibitors and one non-nucleoside reverse transcriptase inhibitor.
Conjunctival Melanoma: Genetic and Epigenetic Insights of a Distinct Type of Melanoma.
Correlation between p38 mitogen-activated protein kinase and human telomerase reverse transcriptase in sarcomas.
Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma.
Different telomere maintenance mechanisms in alveolar and embryonal rhabdomyosarcoma.
Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas.
Dual-color, break-apart fluorescence in situ hybridization for EWS gene rearrangement distinguishes clear cell sarcoma of soft tissue from malignant melanoma.
Efficacy of Pemetrexed-Based Chemotherapy in Patients with ROS1 Fusion-Positive Lung Adenocarcinoma Compared with in Patients Harboring Other Driver Mutations in East Asian Populations.
Elevated telomerase activity, c-MYC-, and hTERT mRNA expression: association with tumour progression in malignant lipomatous tumours.
Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-associated PML bodies.
EWS/ETS fusions activate telomerase in Ewing's tumors.
Expression of telomerase activity and telomerase RNA in human soft tissue sarcomas.
Genomic and Transcriptomic Characteristics According to Size of Papillary Thyroid Microcarcinoma.
Glioblastoma in a female neurofibromatosis 1 patient without IDH1, BRAF V600E, and TERT promoter mutations: A case report.
Glioblastoma in neurofibromatosis 1 patients without IDH1, BRAF V600E, and TERT promoter mutations.
High co-expression of PD-L1 and HIF-1? correlates with tumour necrosis in pulmonary pleomorphic carcinoma.
Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay.
Human sarcomas are mosaic for telomerase-dependent and telomerase-independent telomere maintenance mechanisms: implications for telomere-based therapies.
Immunohistochemical detection of hTERT protein in soft tissue sarcomas: correlation with tumor grade.
Immunohistochemistry for human telomerase reverse transcriptase catalytic subunit (hTERT): a study of 143 benign and malignant soft tissue and bone tumours.
In situ reverse-transcriptase polymerase chain reaction demonstration of the EWS/FLI-1 fusion transcript in Ewing's sarcomas and peripheral primitive neuroectodermal tumors.
In vitro transcription of 70S RNA by the RNA-directed DNA polymerase of Rouse sarcoma virus: lack of influence of RNase H.
Inhibition of oncornavirus functions by 2'-azido polynucleotides.
Inhibition of telomerase activity in human cancer cells by RNA interference.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
Mechanixm of Carcinogenesis By RNA Tumor Viruses, I. An RNA-Dependent DNA Polymerase In Murine Sarcoma Viruses.
Metastatic-prone telomerase reverse transcriptase (TERT) promoter and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutated tall cell variant of papillary thyroid carcinoma arising in ectopic thyroid tissue: A case report.
Molecular classification of gliomas.
Murine sarcoma virus defectiveness. Viral polymerase expression in murine and nonmurine host cells transformed by S + L - type murine sarcoma virus.
Mutation of TP53 gene is involved in carcinogenesis of hepatic undifferentiated (embryonal) sarcoma of the adult, in contrast with Wnt or telomerase pathways: an immunohistochemical study of three cases with genomic relation in two cases.
On chip electrochemical detection of sarcoma protein kinase and HIV-1 reverse transcriptase.
On telomere shortening in soft-tissue tumors.
Prevalence of telomerase activity in human cancer.
Prognostic significance of telomerase activity in soft tissue sarcomas.
Quantitative measurement of telomerase activity and localization of its catalytic subunit (hTERT) in chronic inflammation of capsule formation around various model implants and in sarcomas in a rat model.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Relative contribution of normal and neoplastic cells determines telomerase activity and telomere length in primary cancers of the prostate, colon, and sarcoma.
Revertants of human cells transformed by murine sarcoma virus.
Ribosomal frameshifting at the Gag-Pol junction in avian leukemia sarcoma virus forms a novel cleavage site.
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells.
Strandedness and complementarity of DNA from long-term RNA-dependent DNA polymerase reactions of Soehner-Dmochowski murine sarcoma virus.
Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.
Suramin: a potent inhibitor of the reverse transcriptase of RNA tumor viruses.
Telomerase Activation in Malignant Bone Tumors.
Telomerase Activity and Expression of hTR and TERT in Human Soft Tissue Sarcomas.
Telomerase activity and expression of hTRT and hTR in gastrointestinal stromal tumors in comparison with extragastrointestinal sarcomas.
Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas.
Telomerase activity and human telomerase reverse transcriptase mRNA expression are correlated with clinical aggressiveness in soft tissue tumors.
Telomerase activity and human telomerase reverse transcriptase mRNA expression in soft tissue tumors: correlation with grade, histology, and proliferative activity.
Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients.
Telomerase activity in cell lines of pediatric soft tissue sarcomas.
Telomerase activity in needle biopsied uterine myoma-like tumors: differential diagnosis between uterine sarcomas and leiomyomas.
Telomerase activity in skeletal sarcomas.
Telomerase activity in soft-tissue and bone sarcomas.
Telomerase activity is not altered by regular strenuous exercise in skeletal muscle or by sarcoma in liver of rats.
Telomerase activity of sarcoma cell lines and fibroblasts is independent of p53 status.
Telomerase activity with concurrent loss of cell cycle regulation in feline post-traumatic ocular sarcomas.
Telomerase activity: comparison between fine-needle aspiration and biopsy specimens for the detection of tumor cells.
Telomeres and telomerase in sarcomas.
Template specificities of a RNA-directed DNA polymerase from a human homologous mixed mesodermal sarcoma.
TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas.
The alternative lengthening of telomeres pathway may operate in non-neoplastic human cells.
Utility of sarcoma-specific fusion gene analysis in paraffin-embedded material for routine diagnosis at a specialist centre.
[Application of BRAF in the diagnosis and treatment of thyroid papillary carcinoma].
[Clinical value of BRAF V600E in thyroid carcinoma and the effect of telomerase reverse transcriptase promoter mutations].
Sarcoma, Avian
Anti-tumor virus activity of copper-binding drugs.
Characterization of ribosomal frameshifting in HIV-1 gag-pol expression.
Complementation studies with Rous sarcoma virus gag and gag-pol polyprotein mutants.
Detection of RNA-dependent DNA polymerase activity in the Xiphophorus melanoma system.
Detection of RNA-instructed DNA polymerase in the mitochondria of Rous sarcoma cells using sephadex G-150 thin-layer gel filtration.
DNA-processing activities associated with the purified alpha, beta 2, and alpha beta molecular forms of avian sarcoma virus RNA-dependent DNA polymerase.
Effect of antabuse (disulfiram) on Rous sarcoma virus and on eukaryotic cells.
Effect of isonicotinic acid hydrazide-copper complex on Rous sarcoma virus and its genome RNA.
Effect of p15-associated protease from an avian RNA tumor virus on avian virus-specific polyprotein precursors.
Effect of viral RNase H on the avian sarcoma viral genome during early transcription in vitro.
Efficeint transcription of RNA into DNA by avian sarcoma virus polymerase.
Elongation of DNA complementary to the 5' end of the avian sarcoma virus genome by the virion-associated RNA-dependent DNA polymerase.
Endogenous DNA polymerase of a transformation-defective rous sarcoma virus: characterization and comparison with the enzyme of the non-defective parent.
Expression of the Rous sarcoma virus pol gene by ribosomal frameshifting.
Extent of transcription by the RNA-dependent DNA polymerase of Rous sarcoma virus.
Impaired cleavage of the joint gag-pol polyprotein precursor and virion assembly in a temperature-sensitive mutant of Rous sarcoma virus.
In vitro transcription of 70S RNA by the RNA-directed DNA polymerase of Rouse sarcoma virus: lack of influence of RNase H.
In vitro transcription of DNA from the 70S RNA of Rous sarcoma virus: identification and characterization of various size classes of DNA transcripts.
Inhibition of RNA-dependent DNA polymerase of Rous sarcoma virus by thiosemicarbazones and several cations.
Inhibition of the RNA dependent DNA polymerase and the malignant transforming ability of Rous sarcoma virus by thiosemicarbazone-transition metal complexes.
Initiation of DNA synthesis by the avian oncornavirus RNA-directed DNA polymerase: tryptophan tRNA as the major species of primer RNA.
Interaction between the negative regulator of splicing element and a 3' splice site: requirement for U1 small nuclear ribonucleoprotein and the 3' splice site branch point/pyrimidine tract.
Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins.
Mutation of a termination codon affects src initiation.
N-Methyl isatin beta-thiosemicarbazone-copper complex inhibits RNA-dependent DNA polymerase but not ribonuclease H of Rous sarcoma virus.
New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors.
Nucleotide sequence at the 5' terminus of the avian sarcoma virus genome.
Nucleotide sequence that binds primer for DNA synthesis to the avian sarcoma virus genome.
Presence of viral RNA-instructed DNA polymerase in the oncogenic subviral particles (virosomes) isolated from the mitochondria of rous sarcoma cells.
Processing of avian retroviral gag polyprotein precursors is blocked by a mutation at the NC-PR cleavage site.
Regulation of Rous sarcoma virus RNA-dependent DNA polymerase isoenzymes by in vitro phosphorylation-dephosphorylation.
Reverse transcriptase associated with avian sarcoma-leukosis viruses. I. Comparison of intra-virion content of multiple enzyme forms.
Reverse transcriptase associated with avian sarcoma-leukosis viruses. II. Comparison of subunit structure and catalytic properties.
Ribosomal frameshifting at the Gag-Pol junction in avian leukemia sarcoma virus forms a novel cleavage site.
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells.
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
RNA-dependent DNA polymerase in virions of Rous sarcoma virus. 1970.
RNA-dependent DNA polymerase of avian sarcoma virus B77. I. Isolation and partial characterization of the alpha, beta2, and alphabeta forms of the enzyme.
RNA-dependent DNA polymerase of avian sarcoma virus B77. II. Comparison of the catalytic properties of the alpha, beta2, and alphabeta enzyme forms.
RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template.
RNA-directed DNA synthesis by the DNA polymerase of Rous sarcoma virus: structural and functional identification of 4S primer RNA in uninfected cells.
Rous sarcoma virus RNA stability requires an open reading frame in the gag gene and sequences downstream of the gag-pol junction.
Secondary structure and mutational analysis of the ribosomal frameshift signal of rous sarcoma virus.
Sequence and comparative structural analysis of the murine leukaemia virus amphotropic strain 4070A RNase H domain.
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region.
Synthesis and processing of polymerase proteins of wild-type and mutant avian retroviruses.
The RNA-dependent DNA polymerase of avian sarcoma virus B77. Binding of viral and nonviral ribonucleic acids to the alpha, beta2, and alphabeta forms of the enzyme.
Thermodynamic stability and statistical significance of potential stem-loop structures situated at the frameshift sites of retroviruses.
Two avian sarcoma virus mutants with defects in the DNA polymerase-RNase H complex.
Viral RNA-dependent DNA polymerase RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Sarcoma, Clear Cell
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.
Dual-color, break-apart fluorescence in situ hybridization for EWS gene rearrangement distinguishes clear cell sarcoma of soft tissue from malignant melanoma.
Sarcoma, Ewing
Bone marrow mesenchymal stem cells: historical overview and concepts.
Characterization of the malignant melanoma of soft-parts cell line GG-62 by expression analysis using DNA microarrays.
Detection of circulating tumor cells in patients with Ewing's sarcoma and peripheral primitive neuroectodermal tumor.
Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas.
Doxorubicin modulates telomerase activity in Ewing's sarcoma in vitro and in vivo.
E1AF, an ets-oncogene family transcription factor.
Enhanced expression of PP1gamma1, a catalytic subunit isoform of protein phosphatase type1 and expression of telomerase activity in Ewing's sarcoma cells.
EWS/ETS fusions activate telomerase in Ewing's tumors.
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
hTERT Is highly expressed in Ewing's sarcoma and activated by EWS-ETS oncoproteins.
Molecular cytogenetic parameters in Ewing sarcoma.
Radiation-induced changes of telomerase activity in a human Ewing xenograft tumor.
RT-PCR evaluation of peripheral blood, bone marrow and peripheral blood stem cells in children and adolescents undergoing VACIME chemotherapy for Ewing's sarcoma and alveolar rhabdomyosarcoma.
Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients.
[Detection of minimal residual disease in Ewing's sarcoma using RT-PCR]
Sarcoma, Kaposi
Interferon and other biologic agents for the treatment of Kaposi's sarcoma.
Spindle cells from Acquired Immune Deficiency Syndrome (AIDS)-associated Kaposi's sarcoma (KS) lesions express telomerase activity directly relating to the RNA levels of fibroblast growth factor (FGF)-2.
Spindle cells from AIDS-associated Kaposi's sarcoma lesions express telomerase activity that is enhanced by Kaposi's sarcoma progression factors.
Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.
Telomerase promoter mutations in human immunodeficiency virus-related conjunctiva neoplasia.
Sarcoma, Myeloid
RNA-dependent DNA polymerase activity in ocular granulocytic sarcoma associated to acute myelomonocytic leukemia in Turkish children. Biochemical and immunological characterization of the enzyme.
Sarcoma, Synovial
Detection of the SYT-SSX chimeric RNA of synovial sarcoma in paraffin-embedded tissue and its application in problematic cases.
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
Reverse transcriptase polymerase chain reaction on fine needle aspirates for rapid detection of translocations in synovial sarcoma.
SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.
[Detection and analysis of SYT-SSX fusion gene in synovial sarcoma]
Sarcopenia
Novel Neuroendocrine and Metabolic Mechanism Provides the Patented Platform for Important Rejuvenation Therapies: Targeted Therapy of Telomere Attrition and Lifestyle Changes of Telomerase Activity with the Timing of Neuron-Specific Imidazole-Containing Dipeptide-Dominant Pharmaconutrition Provision.
Schistosomiasis
Detection of telomerase in urine by 3 methods: evaluation of diagnostic accuracy for bladder cancer.
Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis.
Scleroderma, Systemic
Telomerase activity in connective tissue diseases: elevated in rheumatoid arthritis, but markedly decreased in systemic sclerosis.
The polymorphism of telomerase RNA component gene in patients with systemic sclerosis.
Scrapie
hTERT-immortalized ovine microglia propagate natural scrapie isolates.
Seizures
Novel swine-origin influenza A (H1N1) viral encephalitis.
Seizures and tissue injury induce telomerase in hippocampal microglial cells.
Seminoma
Aberrant expression and distribution of the OCT-4 transcription factor in seminomas.
Expression of a telomerase-associated gene in normal, atrophic, and tumorous testes.
Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors.
Sepsis
Study on the functions and mechanism of immune functions of human telomerase reverse transcriptase regulating dendritic cells treating sepsis.
Sertoli Cell Tumor
Measurement of telomerase activity in dog tumors.
Sertoli Cell-Only Syndrome
Highly sensitive quantitative telomerase assay of diagnostic testicular biopsy material predicts the presence of haploid spermatogenic cells in therapeutic testicular biopsy in men with Sertoli cell-only syndrome.
Telomerase activity and expression of telomerase subunits in the testicular tissue of infertile patients.
Sertoli-Leydig Cell Tumor
[Immunohistochemical study on telomerase activity in ovarian sex-cord stromal tumors]
Severe Acute Respiratory Syndrome
Accuracy of Emergency Department Clinical Findings for Diagnosis of Coronavirus Disease 2019.
Atypical symptoms, SARS-CoV-2 test results and immunisation rates in 456 residents from eight nursing homes facing a COVID-19 outbreak.
Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS-CoV-2 agents?
Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population.
Experience of an Orthopaedic Surgery Department Early During the COVID-19 Outbreak in Japan Including Real-Time Polymerase Chain Reaction Assay Results for SARS-CoV-2.
Experience With Pretravel Testing for SARS-CoV-2 at an Academic Medical Center.
False-Negative Nasopharyngeal Swab RT-PCR Assays in Typical COVID-19: Role of Ultra-low-dose Chest CT and Bronchoscopy in Diagnosis.
False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases.
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Rapid, Sensitive, and Specific Severe Acute Respiratory Syndrome Coronavirus 2 Detection: A Multicenter Comparison Between Standard Quantitative Reverse-Transcriptase Polymerase Chain Reaction and CRISPR-Based DETECTR.
Rhino-Orbital Mucormycosis Associated With COVID-19.
Successful treatment of 28 patients with coronavirus disease 2019 at a medical center in Taiwan.
Sex Cord-Gonadal Stromal Tumors
Telomerase activity in sex cord-stromal tumors of the ovary.
Sexually Transmitted Diseases
HIV infection.
Shwachman-Diamond Syndrome
Shwachman-Diamond Syndrome Protein SBDS Maintains Human Telomeres by Regulating Telomerase Recruitment.
Silicosis
Activation of telomerase by silica in rat lung.
Telomerase gene variants and telomere shortening in patients with silicosis or asbestosis.
Sinusitis
Infectious agents associated with respiratory disease in pheasants.
Nasal mucosa expression of lactoferrin in patients with chronic rhinosinusitis.
Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and alternaria in a nasal explant model.
Skin Diseases
Detection of telomerase activity in psoriasis lesional skin and correlation with Ki-67 expression and suppression by retinoic acid.
Expression of telomerase reverse transcriptase in psoriatic lesional skin.
The role of telomerase activity in psoriatic skin lesions.
The role of telomeres in the ageing of human skin.
Skin Neoplasms
Evaluation of telomerase in non-melanoma skin cancer.
Growth arrest of immortalized human keratinocytes and suppression of telomerase activity by p21WAF1 gene expression.
Melanomas of unknown primary frequently harbor TERT-promoter mutations.
Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.
Retinoic acid suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma.
Telomerase activity in melanoma and non-melanoma skin cancer.
Telomerase expression in benign and malignant skin neoplasms: comparison of three major subunits.
Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma.
TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma.
The different telomere lengths in basal and squamous cell carcinomas also differ between the nontransplant and renal transplant population.
The higher incidence of squamous cell carcinoma in renal transplant recipients is associated with increased telomere lengths.
[Telomerase]
Skin Ulcer
Expression of telomerase reverse transcriptase in radiation-induced chronic human skin ulcer.
Telomerase activity in radiation-induced chronic human skin ulcers.
Sleep Apnea, Obstructive
Coexistence of obstructive sleep apnea and telomerase activity, concentration of selected adipose tissue hormones and vascular endothelial function in patients with arterial hypertension.
Small Cell Lung Carcinoma
Adenovirus-mediated HSV-TK gene therapy using the human telomerase promoter induced apoptosis of small cell lung cancer cell line.
EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung.
Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.
Telomerase activity in endoscopically visible lung cancer.
Telomerase activity in pulmonary neuroendocrine tumors: correlation with histologic subtype (MS-0060).
[Study on telomerase activity and its clinical value in human non small cell lung cancer]
Smoldering Multiple Myeloma
Expression Profile of Telomere-associated Genes in Multiple Myeloma.
Smooth Muscle Tumor
Telomerase activity in needle biopsied uterine myoma-like tumors: differential diagnosis between uterine sarcomas and leiomyomas.
Solitary Fibrous Tumors
Expression profile of telomerase subunits in human pleural mesothelioma.
Solitary fibrous tumors: loss of chimeric protein expression and genomic instability mark dedifferentiation.
Telomerase activity in human pleural mesothelioma.
Telomerase activity, Ki-67, cyclin D1 and A expression, and apoptosis in solitary fibrous tumors: additional features of a predictable course?
Telomerase promoter mutations and copy number alterations in solitary fibrous tumours.
TERT promoter mutations and prognosis in solitary fibrous tumor.
Solitary Pulmonary Nodule
The value of chest CT scan and tumor markers detection in sputum for early diagnosis of peripheral lung cancer.
Somatostatinoma
Characterization of the functional and growth properties of long-term cell cultures established from a human somatostatinoma.
Spinal Cord Injuries
Role of telomerase reverse transcriptase in glial scar formation after spinal cord injury in rats.
Telomerase expression in the glial scar of rats with spinal cord injury.
Transplantation of human telomerase reverse transcriptase gene-transfected Schwann cells for repairing spinal cord injury.
[Experimental study of the correlation of telomerase and intramedullary scar after spinal cord injury in rats].
Spinal Stenosis
SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients.
Squamous Cell Carcinoma of Head and Neck
67-kDa laminin receptor in human laryngeal squamous cell carcinoma.
A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma.
A New Strategy to Find Targets for Anticancer Therapy: Chemokine CXCL14/BRAK Is a Multifunctional Tumor Suppressor for Head and Neck Squamous Cell Carcinoma.
Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression.
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Association between clincopathological characteristics and hTERT expression as well as telomere length in ameloblastoma.
Azacitidine, as a DNMT inhibitor decreases hTERT gene expression and telomerase activity more effective compared with HDAC inhibitor in human Head and neck squamous cell carcinoma cell lines.
Change of telomerase activity in peripheral blood of patients with head and neck squamous cell carcinoma pre and post curative treatment.
Change of telomerase activity in peripheral whole blood of head and neck squamous cell carcinoma patients before and after surgery: a pilot study.
Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines.
Combined evaluation of expression of telomerase, survivin, and anti-apoptotic Bcl-2 family members in relation to loss of differentiation and apoptosis in human head and neck cancers.
Correlation of dyskerin expression with active proliferation independent of telomerase.
Correlation of telomerase activity, clinical prognosis and therapy in oral carcinogenesis.
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Detection of telomerase activity in saliva from oral squamous cell carcinoma patients.
Effect of silencing key proteins in telomerase mechanism and alternative lengthening of telomeres mechanism in laryngeal cancer cells.
Expression of hTERT in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma - an Immunohistochemical Analysis.
Expression of human telomerase reverse transcriptase (hTERT) protein is significantly associated with the progression, recurrence and prognosis of oral squamous cell carcinoma in Taiwan.
Expression of human telomerase reverse transcriptase protein in oral epithelial dysplasia and oral squamous cell carcinoma: An immunohistochemical study.
Expression of telomerase components in oral keratinocytes and squamous cell carcinomas.
Expression of VEGF, HGF, IL-6, IL-8, MMP-9, Telomerase in Peripheral Blood of Patients with Head and Neck Squamous Cell Carcinoma.
Frequent high telomerase reverse transcriptase expression in primary oral squamous cell carcinoma.
hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer.
Human telomerase reverse transcriptase expression and its clinical significance in laryngeal squamous cell carcinoma.
Human telomerase reverse transcriptase regulates cyclin D1 and G1/S phase transition in laryngeal squamous carcinoma.
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Immunohistochemical expression of p53, p16 and hTERT in oral squamous cell carcinoma and potentially malignant disorders.
Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells.
miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.
Molecular characterization of head and neck tumors by analysis of telomerase activity and a panel of microsatellite markers.
Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour.
Overexpression of cell cycle regulatory proteins correlates with advanced tumor stage in head and neck squamous cell carcinomas.
Predicting clinical outcome in feline oral squamous cell carcinoma: tumour initiating cells, telomeres and telomerase.
Predictive and prognostic significance of telomerase levels/telomere length in tissues and peripheral blood in head and neck squamous cell carcinoma.
Prognostic value of cell-cycle regulators and cellular biomarkers in laryngeal squamous cell carcinoma.
Prognostic value of human telomerase reverse transcriptase gene expression in oral carcinogenesis.
Promoter region mutations of the telomerase reverse transcriptase (TERT) gene in head and neck squamous cell carcinoma.
Quantification of telomerase activity in normal oral mucosal tissue and oral squamous cell carcinoma.
Quantification of telomerase activity of regions unstained with iodine solution that surround oral squamous cell carcinoma.
Quantitative assay of telomerase activity in head and neck squamous cell carcinoma and other tissues.
Radiosensitizing Potential of Curcumin in Different Cancer Models.
Regulation of Epithelial Cell Proliferation, Differentiation, and Plasticity by Grainyhead-Like 2 During Oral Carcinogenesis.
Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells.
RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.
Short hairpin ribonucleic acid targeting the telomerase catalytic unit of messenger ribonucleic acid significantly limits the growth of laryngeal squamous cell carcinoma in nude mice.
Synergistic down-regulation of telomerase by all-trans retinoic acid and antisense oligonucleotide in oral squamous cell carcinoma cell line (Tca8113).
Targeted therapy of human laryngeal squamous cell carcinoma in vitro by antisense oligonucleotides directed against telomerase reverse transcriptase mRNA.
Telomerase activity and in situ telomerase RNA expression in oral carcinogenesis.
Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.
Telomerase activity in head and neck tumors after introduction of wild-type p53, p21, p16, and E2F-1 genes by means of recombinant adenovirus.
Telomerase activity in laryngeal squamous cell carcinoma.
Telomerase activity in oral and maxillofacial tumors.
Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma.
Telomerase activity in oral squamous cell carcinoma.
Telomerase activity in premalignant and malignant lesions of human oral mucosa.
Telomerase activity in the occurrence and progression of oral squamous cell carcinoma.
Telomerase activity is upregulated in laryngeal squamous cell carcinoma.
Telomerase as an independent prognostic factor in head and neck squamous cell carcinoma.
Telomerase catalytic subunit gene expression does not influence survival of patients with squamous cell carcinoma of the larynx and hypopharynx: a case-control study.
Telomerase in saliva: An assistant marker for oral squamous cell carcinoma.
Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma.
Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With Felis catus Papillomavirus Type-2 Infection.
Telomerase reverse transcriptase interference synergistically promotes tumor necrosis factor?related apoptosis?inducing ligand?induced oral squamous cell carcinoma apoptosis and suppresses proliferation in vitro and in vivo.
Telomerase reverse transcriptase potentially promotes the progression of oral squamous cell carcinoma through induction of epithelial-mesenchymal transition.
Telomerase: An exploration toward the end of cancer.
Telomere shortening in mucosa surrounding the tumor: biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell carcinoma.
Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.
TERT promoter hotspot mutations and their relationship with TERT levels and telomere erosion in patients with head and neck squamous cell carcinoma.
TERT Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients.
TERT promoter mutation in patients with second primary of tongue squamous cell carcinoma.
TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.
The predictive and therapeutic value of thymidine phosphorylase and dihydropyrimidine dehydrogenase in capecitabine (Xeloda)-based chemotherapy for head and neck cancer.
The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma.
The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC.
The Small Molecule BIBR1532 Exerts Potential Anti-cancer Activities in Preclinical Models of Feline Oral Squamous Cell Carcinoma Through Inhibition of Telomerase Activity and Down-Regulation of TERT.
YY1 Promotes Telomerase Activity and Laryngeal Squamous Cell Carcinoma Progression Through Impairment of GAS5-Mediated p53 Stability.
[Expression of telomerase genes hTRTmRNA in oral squamous cell carcinomas.]
[Expression of telomerase reverse transcriptase and its relationship with expression of c-myc in laryngeal squamous cell carcinomas]
[Genic alterations in oral and head and neck squamous cell carcinomas: analysis of international literature]
[hTERT promoter enhances the radiosensitivity to gene-radiation therapy of human laryngeal carcinoma transplanted in nude mice]
[Inhibitory Effect of Silencing hTERT Gene by Short Hairpin RNA on Growth of Human Laryngeal Squamous Cell Carcinoma Xenograft in Nude Mice.]
[Quantitative assay of telomerase activity in head and neck squamous cell carcinoma]
[Research on expression of human papillomavirus type 16 and telomerase in oral lesions]
[Study and detection of telomerase activity in oral squamous cell carcinomas and precancerous lesions]
[Targeted therapy of human laryngeal squamous cell carcinoma in vitro with telomerase catalytic subunit mRNA]
[Telomerase activity in human head and neck squamous cell carcinoma and adjacent tissues]
[Telomerase activity in oral squamous cell carcinoma and leukoplakia]
[Telomerase SiRNA inhibits KB cell growth in human oral squamous cell carcinoma.]
[The expressions of telomerase activity and cyclinD1 protein in laryngeal squamous cell carcinoma]
Starvation
Glutamine starvation of murine leukaemia virus-infected cells inhibits the readthrough of the gag-pol genes and proteolytic processing of the gag polyprotein.
Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells.
Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle.
The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes.
Stevens-Johnson Syndrome
Severe cutaneous reactions associated with the use of human immunodeficiency virus medications.
Stillbirth
Improved obstetric outcomes and few maternal toxicities are associated with antiretroviral therapy, including highly active antiretroviral therapy during pregnancy.
Stomach Diseases
Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases.
[Coordinated expression of c-Myc and telomerase activity in Helicobacter pylori infected gastric diseases]
Stomach Neoplasms
A new mutL homolog 1 c.1896+5G>A germline mutation detected in a Lynch syndrome-associated lung and gastric double primary cancer patient.
A novel telomere elongation in an adriamycin-resistant stomach cancer cell line with decreased telomerase activity.
Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism.
Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c-Myc expression.
Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients.
AKT Activation and Telomerase Reverse Transcriptase Expression are Concurrently Associated with Prognosis of Gastric Cancer.
Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions.
An anti-apoptosis gene, survivin and telomerase expression in gastric cancer.
Antiproliferative effect of octreotide on gastric cancer cells mediated by inhibition of Akt/PKB and telomerase.
Antisense telomerase RNA induced human gastric cancer cell apoptosis.
Apoptosis induction by glycoprotein isolated from Laminaria japonica is associated with down-regulation of telomerase activity and prostaglandin E2 synthesis in AGS human gastric cancer cells.
Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
Calcium-sensing receptor bridges calcium and telomerase reverse transcriptase in gastric cancers via Akt.
Change in number and size of circulating tumor cells with high telomerase activity during treatment of patients with gastric cancer.
Circulating cell-free human telomerase reverse transcriptase mRNA in plasma and its potential diagnostic and prognostic value for gastric cancer.
Clinical significance of telomerase activity in biopsy specimens of gastric cancer.
Clinical significance of telomerase activity in gastric carcinoma and peritoneal dissemination.
Clinical significance of telomerase activity in peritoneal lavage fluid from patients with gastric cancer and its relationship with cellular proliferation.
Clinical usefulness of telomerase activity and telomere length in the preoperative diagnosis of gastric and colorectal cancer.
Coordinate increase of telomerase activity and c-Myc expression in Helicobacter pylori-associated gastric diseases.
Correlation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancer.
Correlation between telomerase activity and DNA ploidy in gastric cancer.
Correlation between telomerase activity and matrix metalloproteinases 2 expression in gastric cancer.
Correlation between telomerase activity and telomeric-repeat binding factors in gastric cancer.
Cyclooxygenase-2 inhibitor nimesulide suppresses telomerase activity by blocking Akt/PKB activation in gastric cancer cell line.
Cystatin M expression is reduced in gastric carcinoma and is associated with promoter hypermethylation.
Decrease of telomeres and increase of interstitial telomeric sites in chromosomes of short-term cultured gastric carcinoma cells detected by fluorescence in situ hybridization.
Detection of telomerase activity in gastric lavage fluid: a novel method to detect gastric cancer.
Detection of telomerase activity in peritoneal lavage fluid from patients with gastric cancer using immunomagnetic beads.
Development of a high-throughput membrane-array method for molecular diagnosis of circulating tumor cells in patients with gastric cancers.
DNA Methylation Profiling of hTERT Gene Alongside with the Telomere Performance in Gastric Adenocarcinoma.
DNA ploidy, S phase fraction and telomerase activity in gastric cancer.
Effect of antisense human telomerase RNA transfection on the growth of human gastric cancer cell lines.
Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells.
Effects of genomic imbalances on telomerase activity in gastric cancer: clues to telomerase regulation.
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Expression of human telomerase catalytic subunit gene in cancerous and precancerous gastric conditions.
Expression of human telomerase RNA is an early event of stomach carcinogenesis.
Expression of NF-kappaB and human telomerase reverse transcriptase in gastric cancer and precancerous lesions.
Expression of Tankyrase 1 in Gastric Cancer and Its Correlation with Telomerase Activity.
Expression of telomerase activity, human telomerase RNA, and telomerase reverse transcriptase in gastric adenocarcinomas.
Expression of telomerase catalytic component, telomerase reverse transcriptase, in human gastric carcinomas.
Expression of telomerase subunits in gastric cancer.
Expression of telomerase-associated genes: reflection of telomerase activity in gastric cancer?
Expression of telomere binding proteins in gastric cancer and correlation with clinicopathological parameters.
Expression of the full-length telomerase reverse transcriptase (hTERT) transcript in both malignant and normal gastric tissues.
Expression of thrombospondin-1 is correlated with microvessel density in gastric carcinoma.
Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer.
G-quadruplex antibody attenuates human gastric cancer cell proliferation and promotes apoptosis through hTERT/telomerase pathway.
Gastric cancer cell detection in peritoneal lavage: RT-PCR for carcinoembryonic antigen transcripts versus the combined cytology with peritoneal carcinoembryonic antigen levels.
Gastric cancer with high telomerase activity shows rapid development and invasiveness.
Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer.
Gene expression of 5-fluorouracil metabolic enzymes in primary gastric cancer: correlation with drug sensitivity against 5-fluorouracil.
H. pylori induces a novel NF-?B/Lin28A/let-7a/hTERT axis to promote gastric carcinogenesis.
Helicobacter pylori and telomerase activity in intestinal metaplasia of the stomach.
Helicobacter pylori infection and carcinogenesis of the stomach.
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.
Helicobacter pylori infection: augmentation of telomerase activity in cancer and noncancerous tissues.
Histone Acetylation and Retinoic Acid Receptor beta DNA Methylation as Novel Targets for Gastric Cancer Therapy.
hTERT methylation and expression in gastric cancer.
Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression.
Increased phosphorylation of AKT in high-risk gastric mucosa.
Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer.
Inhibition of human telomerase in MKN-45 cell line by antisense hTR expression vector induces cell apoptosis and growth arrest.
Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors.
Inhibitory effect of human telomerase antisense oligodeoxyribonucleotides on the growth of gastric cancer cell lines in variant tumor pathological subtype.
Integrated fluorescent cytology with nano-biologics in peritoneally disseminated gastric cancer.
Irradiation-induced telomerase activity and gastric cancer risk: a case-control analysis in a Chinese Han population.
Loss of heterozygosity and histone hypoacetylation of the PINX1 gene are associated with reduced expression in gastric carcinoma.
miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase.
miR-199a Regulates the Tumor Suppressor Mitogen-Activated Protein Kinase Kinase Kinase 11 in Gastric Cancer.
Molecular biological observations in gastric cancer.
Molecular detection of disseminated tumor cells in the peripheral blood of patients with gastric cancer: evaluation of their prognostic significance.
Molecular diagnosis of gastric cancer: present and future.
Molecular mechanism of human stomach carcinogenesis implicated in Helicobacter pylori infection.
mRNA Expression Analysis of E-Cadherin, VEGF, and MMPs in Gastric Cancer: a Pilot Study.
Normal and Tumour Tissue mRNA Expressions of Telomerase Complex Genes in Several Types of Cancer.
Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer.
Overexpression of human telomerase RNA in Helicobacter pylori-infected human gastric mucosa.
PinX1 inhibits telomerase activity in gastric cancer cells through Mad1/c-Myc pathway.
Polymorphisms in human telomerase reverse transcriptase (hTERT) gene and susceptibility to gastric cancer in a Turkish population: Hospital-based case-control study.
Polymorphisms in human telomerase reverse transcriptase (hTERT) gene, gene- gene and gene-smoking interaction with susceptibility to gastric cancer in Chinese Han population.
Prognostic impact of the number of viable circulating cells with high telomerase activity in gastric cancer patients: a prospective study.
Prognostic Role of Estrogen Receptor alpha and Estrogen Receptor beta in Gastric Cancer.
Proton pump inhibitor pantoprazole inhibits gastric cancer metastasis via suppression of telomerase reverse transcriptase gene expression.
Real-time determination of human telomerase reverse transcriptase mRNA in gastric cancer.
Relationship between expression of IGFBP7 and clinicopathological variables in gastric cancer.
Relationship between the expression of human telomerase reverse transcriptase gene and cell cycle regulators in gastric cancer and its significance.
Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer.
RESISTIN EFFECT ON TELOMERASE GENE EXPRESSION IN GASTRIC CANCER CELL LINE AGS.
Synergistic Effects of Resistin and Visfatin as Adipocyte Derived Hormones on Telomerase Gene Expression in AGS Gastric Cancer Cell Line.
Telomerase activity and its clinicopathological significance in gastric cancer.
Telomerase activity and telomere lengths in various cell lines: changes of telomerase activity can be another method for chemosensitivity evaluation.
Telomerase activity could be used as a marker for neoplastic transformation in gastric adenocarcinoma: but it does not have a prognostic significance.
Telomerase Activity in Gastric Adenocarcinomas: Frozen Tissues Versus Methacarn-fixed Paraffin-embedded Tissues.
Telomerase activity in gastric cancer and its clinical implications.
Telomerase activity in gastric cancer.
Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.
Telomerase and hTERT: can they serve as markers for gastric cancer diagnosis?
Telomerase reverse transcriptase methylation predicts lymph node metastasis and prognosis in patients with gastric cancer.
Telomerase RNA expression during progression of gastric cancer.
Telomere length and telomerase activity in carcinogenesis of the stomach.
The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer.
The hypoxia/IL1A axis promotes gastric cancer progression and drug resistance.
Tumor interstitial fluid and gastric cancer metastasis: an experimental study to verify the hypothesis of "tumor-phlegm microenvironment".
Up-regulation of Mac-2 binding protein by hTERT in gastric cancer.
Visfatin effects on telomerase gene expression in AGS gastric cancer cell line.
[Coordinated expression of c-Myc and telomerase activity in Helicobacter pylori infected gastric diseases]
[Detection of telomerase activity in gastric cancer and adjacent tissues]
[Detection of telomerase activity in gastric cancer].
[Effect of exopolysaccharide from Bifidobacterium bifidum on cell of gastric cancer and human telomerase reverse transcriptase]
[Effects of antisense human telomerase RNA on growth of human gastric cancer cells]
[Expression of telomere and telomerase in human primary gastric carcinoma]
[Measurement of telomerase activity and telomerase reverse transcriptase expression in gastric fluid and tissue for early diagnosis of stomach cancer]
[miR-29b Reduces Cisplatin Resistance of Gastric Cancer Cell by Targeting PI3K/Akt Pathway].
[Nimesulide, a selective cyclooxygenase-2 inhibitor inhibits telomerase activity by blocking activation of PKB in gastric cancer cell line]
[Preoperative diagnostic laparoscopy with local anesthesia and lavage telomerase activity for advanced gastric cancer]
[Relationship between telomerase activity and clinicopathological findings in gastric cancer]
[Telomerase activity during the cell cycle in gastric cancer cell lines]
[Telomerase activity in gastric cancer and premalignant lesions: determination and its clinical significance]
[Telomerase, cell immortality and cancer]
[Telomere length and telomerase activity in intestinal metaplasia, adenoma and well differentiated adenocarcinoma of the stomach]
[The significance of telomerase activity in patients with gastric cancer]
Stomach Ulcer
Telomerase activity in gastric cancer and its clinical implications.
Stomatitis
Increased in vitro glial fibrillary acidic protein expression, telomerase activity, and telomere length after productive human immunodeficiency virus-1 infection in murine astrocytes.
Stroke
Cerebellar fastigial nucleus electrical stimulatin protects against cerebral ischemic damage by upregulating telomerase activity.
Deficiency of telomerase activity aggravates the blood-brain barrier disruption and neuroinflammatory responses in a model of experimental stroke.
Stroke in patients with SARS-CoV-2 infection: case series.
Telomerase therapeutics for degenerative diseases.
TELOMERE LENGTH, TELOMERASE ACTIVITY, HEART RATE VARIABILITY, OR OXIDATIVE STRESS: WHICH ONE IS MOST ASSOCIATED WITH THE ATHEROTHROMBOTIC STROKE IN THE ELDERLY?
Telomeres and Telomerase in Cardiovascular Diseases.
Synovitis
Different mechanisms of synovial hyperplasia in rheumatoid arthritis and pigmented villonodular synovitis: the role of telomerase activity in synovial proliferation.
Synovitis, Pigmented Villonodular
Different mechanisms of synovial hyperplasia in rheumatoid arthritis and pigmented villonodular synovitis: the role of telomerase activity in synovial proliferation.
Tauopathies
LRP::FLAG Reduces Phosphorylated Tau Levels in Alzheimer's Disease Cell Culture Models.
Telangiectasis
ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
Epigenetic control of telomerase and modes of telomere maintenance in aging and abnormal systems.
Teratocarcinoma
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells.
Inhibition of human endogenous retrovirus-K10 protease in cell-free and cell-based assays.
Selective inhibition of telomerase activity during terminal differentiation of immortal cell lines.
Teratoma
Amniotic Fluid Cells Are More Efficiently Reprogrammed to Pluripotency Than Adult Cells.
Amniotic fluid cells are more efficiently reprogrammed to pluripotency than adult cells.
Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research.
Distinct Responses of Stem Cells to Telomere Uncapping-A Potential Strategy to Improve the Safety of Cell Therapy.
Efficient method for slow cryopreservation of human embryonic stem cells in xeno-free conditions.
Expression of the RNA component of human telomerase in adult testicular germ cell neoplasia.
Generation of high-level stable transgene expressing human embryonic stem cell lines using Chinese hamster elongation factor-1 alpha promoter system.
Generation of high-level stable transgene expressing human embryonic stem cell lines using Chinese hamster elongation factor-1alpha promoter system.
Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumors.
Human adipose tissue possesses a unique population of pluripotent stem cells with nontumorigenic and low telomerase activities: potential implications in regenerative medicine.
Human mid-trimester amniotic fluid stem cells cultured under embryonic stem cell conditions with valproic acid acquire pluripotent characteristics.
Human neural crest-derived postnatal cells exhibit remarkable embryonic attributes either in vitro or in vivo.
Multipotential differentiation of human urine-derived stem cells: Potential for therapeutic applications in urology.
Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues-A Paradigm Shift in Tissue Regeneration and Evolution.
Parthenogenetic Embryo-Like Structures in the Human Ovarian Surface Epithelium Cell Culture in Postmenopausal Women with No Naturally Present Follicles and Oocytes.
Porcine induced pluripotent stem cells analogous to naïve and primed embryonic stem cells of the mouse.
Telomerase activity in germ cell cancers and mature teratomas.
The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase.
Testicular Neoplasms
Aberrant expression and distribution of the OCT-4 transcription factor in seminomas.
Decreased telomerase activity is not a reliable indicator of chemosensitivity in testicular cancer cell lines.
Expression and effects of human telomerase RNA in testicular tumor.
Inhibition of telomerase activity by cisplatin in human testicular cancer cells.
Tetanus
Differential regulation of human, antigen-specific Th1 and Th2 responses by the B-7 homologues, CD80 and CD86.
Thanatophoric Dysplasia
Telomere length, telomerase activity, and expression of human telomerase reverse transcriptase mRNA in growth plate of epiphyseal articular cartilage in femoral head during normal human development and in thanatophoric dysplasia.
Thrombocythemia, Essential
Dynamics of mutations in patients with essential thrombocythemia treated with imetelstat.
Elevated telomerase activity in essential thrombocythemia with extreme thrombocytosis.
High telomerase activity in granulocytes from clonal polycythemia vera and essential thrombocythemia.
Management of thrombocythemia.
Telomerase Inhibitor Imetelstat in Essential Thrombocythemia and Myelofibrosis.
Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia.
The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype.
Thrombocytosis
Analysis of platelets from patients with thrombocythemia for reverse transcriptase and virus-like particles.
Elevated telomerase activity in essential thrombocythemia with extreme thrombocytosis.
[Analysis for telomerase activity in various hematologic disorders]
Thromboinflammation
Extracellular Vesicles and Citrullinated Histone H3 in Coronavirus Disease 2019 Patients.
Thrombosis
Serologic survey for hantavirus infection in domestic animals and coyotes from New Mexico and northeastern Arizona.
Silymarin Inhibits Endothelial Progenitor Cells Senescence and Protects Against the Antiproliferative Activity of Rapamycin. Preliminary Study.
Thymoma
Enhanced expression of telomerase activity in thymoma and thymic carcinoma tissues: a clinicopathologic study.
Increased phosphorylation of AKT in high-risk gastric mucosa.
Telomerase activity in thymomas and mammary gland adenocarcinomas induced by polyoma virus in AKR mice.
[Expression of telomerase activity in thymoma and thymiccarcinoma tissues; a clinicopathological study]
Thyroid Cancer, Papillary
Associations of telomerase reverse transcriptase rs10069690 and rs2736100 polymorphisms with papillary thyroid carcinoma.
BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients.
BRAF V600E and TERT Promoter Mutations in Papillary Thyroid Carcinoma in Chinese Patients.
Clinicopathological significance of TERT promoter mutation in papillary thyroid carcinomas: a systematic review and meta-analysis.
Co-Occurrence of Hotspot Point Mutation and Novel Deletion Mutation of TERT Promoter in Solid Variant Papillary Thyroid Carcinoma in a Patient with Synchronous Esophageal Cancer.
Correlation between telomerase reverse transcriptase messenger RNA expression and survival of patients with papillary thyroid carcinoma.
Highly prevalent BRAF V600E and low-frequency TERT promoter mutations underlie papillary thyroid carcinoma in Koreans.
Human telomerase reverse transcriptase in papillary thyroid cancer: gene expression, effects of silencing and regulation by BET inhibitors in thyroid cancer cells.
Immune cell infiltrate-associated dysregulation of DNA repair machinery may predispose to papillary thyroid carcinogenesis.
In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma.
Lack of germline A339V mutation in thyroid transcription factor-1 (TITF-1/NKX2.1) gene in familial papillary thyroid cancer.
Lack of Mutations of the Telomerase RNA Component in Familial Papillary Thyroid Cancer with Short Telomeres.
Metastatic-prone telomerase reverse transcriptase (TERT) promoter and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutated tall cell variant of papillary thyroid carcinoma arising in ectopic thyroid tissue: A case report.
Mutations of the TERT promoter are associated with aggressiveness and recurrence/distant metastasis of papillary thyroid carcinoma.
Oncofoetal fibronectin--a tumour-specific marker in detecting minimal residual disease in differentiated thyroid carcinoma.
Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer.
Preoperative detection of TERT promoter and BRAFV600E mutations in papillary thyroid carcinoma in high-risk thyroid nodules.
Preoperative detection of the TERT promoter mutations in papillary thyroid carcinomas.
Short telomeres, telomerase reverse transcriptase gene amplification, and increased telomerase activity in the blood of familial papillary thyroid cancer patients.
Suspicious ultrasound and clinicopathological features of papillary thyroid carcinoma predict the status of TERT promoter.
Telomerase activity in thyroid malignancy.
Telomerase activity in well-differentiated papillary thyroid carcinoma correlates with advanced clinical stage of the disease.
Telomerase reverse transcriptase mutations are independent predictor of disease-free survival in Middle Eastern papillary thyroid cancer.
Telomere length and telomerase reverse transcriptase gene copy number in patients with papillary thyroid carcinoma.
Telomeres and thyroid cancer.
TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas.
TERT Promoter Mutations and Their Impact on Gene Expression Profile in Papillary Thyroid Carcinoma.
The clinical significance of PINX1 expression in papillary thyroid carcinoma.
Thyroid carcinomas that express telomerase follow a more aggressive clinical course in children and adolescents.
Topoisomerase II alpha and telomerase expression in papillary thyroid carcinomas.
Transcriptome analysis of papillary thyroid cancer harboring telomerase reverse transcriptase promoter mutation.
Ultrasonographic prediction of highly aggressive telomerase reverse transcriptase (TERT) promoter-mutated papillary thyroid cancer.
Ultrasound and clinicopathological features of papillary thyroid carcinomas with BRAF and TERT promoter mutations.
Thyroid Carcinoma, Anaplastic
Differential effects of TGF-beta1 on telomerase activity in thyroid carcinoma cell lines.
Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines.
Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines.
Silencing of hTERT blocks growth and migration of anaplastic thyroid cancer cells.
Telomerase activity in benign and malignant thyroid tumors.
TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma.
The effects of thymoquinone and genistein treatment on telomerase activity, apoptosis, angiogenesis, and survival in thyroid cancer cell lines.
Thyroid Diseases
In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma.
Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension.
Telomerase activity in benign and malignant thyroid diseases.
[Puncture hystobiopsy with tissue telomerase activity measurement in preoperative thyroid nodes diagnostics]
Thyroid Dysgenesis
Metastatic-prone telomerase reverse transcriptase (TERT) promoter and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutated tall cell variant of papillary thyroid carcinoma arising in ectopic thyroid tissue: A case report.
Thyroid Neoplasms
A Clinical Overview of Telomerase-Associated Aberrancies in Follicular Thyroid Tumors as Diagnostic and Prognostic Markers: Tert Alert!
Amplification of the human epidermal growth factor receptor 2 gene in differentiated thyroid cancer correlates with telomere shortening.
Antisense hTERT inhibits thyroid cancer cell growth.
Arms-qPCR Improves Detection Sensitivity of Earlier Diagnosis of Papillary Thyroid Cancers With Worse Prognosis Determined by Coexisting BRAF V600E and Tert Promoter Mutations.
Association between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis.
Association of telomerase reverse transcriptase promoter mutations with clinicopathological features and prognosis of thyroid cancer: a meta-analysis.
Associations of telomerase reverse transcriptase rs10069690 and rs2736100 polymorphisms with papillary thyroid carcinoma.
BRAF and TERT promoter mutations: clinical application in thyroid cancer.
Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.
Characterization of human telomerase reverse transcriptase promoter methylation and transcription factor binding in differentiated thyroid cancer cell lines.
Clinical application of human telomerase reverse transcriptase gene expression in thyroid follicular tumors by fine-needle aspirations using in situ hybridization.
Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease.
Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.
Comparison of telomerase and CD44 expression as diagnostic tumor markers in lesions of the thyroid.
Correlation between telomerase reverse transcriptase messenger RNA expression and survival of patients with papillary thyroid carcinoma.
Decrease of telomere length in thyroid adenomas without telomerase activity.
Detection of telomerase RNA in the plasma of patients with breast cancer, malignant melanoma or thyroid cancer.
Diagnostic and prognostic TERT promoter mutations in thyroid fine-needle aspiration biopsy.
Differential effects of TGF-beta1 on telomerase activity in thyroid carcinoma cell lines.
Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms.
Dissociation of telomere dynamics from telomerase activity in human thyroid cancer cells.
Effects of Coexistent BRAF(V600E) and TERT Promoter Mutations on Poor Clinical Outcomes in Papillary Thyroid Cancer: A Meta-Analysis.
Establishment and characterization of OCUT-1, an undifferentiated thyroid cancer cell line expressing high level of telomerase.
Expression of human telomerase reverse transcriptase (hTERT) in thyroid neoplasms.
Expression of telomerase genes in thyroid carcinoma.
Frequency of TERT promoter mutations in human cancers.
Function of HSP90 and p23 in the telomerase complex of thyroid tumors.
Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma.
Highly prevalent TERT promoter mutations in aggressive thyroid cancers.
hTERT gene polymorphism correlates with the risk and the prognosis of thyroid cancer.
Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasms.
Human telomerase reverse transcriptase (hTERT) gene expression in thyroid carcinoma: diagnostic and prognostic role.
Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms.
Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.
Human telomerase reverse transcriptase in papillary thyroid cancer: gene expression, effects of silencing and regulation by BET inhibitors in thyroid cancer cells.
LncRNA FOXD2-AS1 Functions as a Competing Endogenous RNA to Regulate TERT Expression by Sponging miR-7-5p in Thyroid Cancer.
Low Prevalence of Somatic TERT Promoter Mutations in Classic Papillary Thyroid Carcinoma.
Low telomerase activity: possible role in the progression of human medullary thyroid carcinoma.
miR-195-5p regulates cell proliferation, apoptosis, and invasion of thyroid cancer by targeting telomerase reverse transcriptase.
Mouse Models as a Tool for Understanding Progression in BrafV600E-Driven Thyroid Cancers.
Mutation Profile of Well-Differentiated Thyroid Cancer in Asians.
New attempt of preoperative differential diagnosis of thyroid neoplasms by telomerase activity measurement.
Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases.
Prevalence of telomerase activity in human cancer.
Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM staging system in differentiated thyroid cancer patients.
Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAF(V600E) Mutation-Prevalent Population.
Proposal of a New Prognostic Model for Differentiated Thyroid Cancer with TERT Promoter Mutations.
Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential: Advantages of the Digital Droplet PCR Technique.
Telomerase activity and telomere length in benign and malignant human thyroid tissues.
Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications.
Telomerase activity in "suspicious" thyroid cytology.
Telomerase activity in benign and malignant human thyroid tissues.
Telomerase activity in benign and malignant thyroid diseases.
Telomerase activity in benign and malignant thyroid tumors.
Telomerase activity in fine needle aspiration biopsy samples: application to diagnosis of human thyroid carcinoma.
Telomerase activity in human thyroid carcinomas originating from the follicular cells.
Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid.
Telomerase activity in thyroid malignancy.
Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT).
Telomerase activity in thyroid tumors.
Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.
Telomerase and Telomeres Biology in Thyroid Cancer.
Telomerase as drug and drug target for the treatment of thyroid cancer.
Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization.
Telomerase promoter mutations in cancer: an emerging molecular biomarker?
Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review.
Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway.
Telomerase reverse transcriptase mutations in thyroid carcinoma.
Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology-a narrative review.
Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma.
Telomeres and thyroid cancer.
TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours.
TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA.
TERT promoter mutation predicts radioiodine refractory in distant metastatic differentiated thyroid cancer.
TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer.
TERT Promoter Mutations and Tumor Persistence/Recurrence in Papillary Thyroid Cancer.
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas.
TERT promoter mutations in thyroid cancer.
TERT Promoter Mutations in Thyroid Cancer.
TERT promoter mutations in thyroid cancer: a report from a Middle Eastern population.
The correlations between DNA methylation and polymorphisms in the promoter region of the human telomerase reverse transcriptase (hTERT) gene with postoperative recurrence in patients with thyroid carcinoma (TC).
The effects of thymoquinone and genistein treatment on telomerase activity, apoptosis, angiogenesis, and survival in thyroid cancer cell lines.
The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of TERT Promoter Mutations.
The role of TERT promoter mutations in postoperative and preoperative diagnosis and prognosis in thyroid cancer.
Thyroid carcinomas that express telomerase follow a more aggressive clinical course in children and adolescents.
Transcriptome analysis of papillary thyroid cancer harboring telomerase reverse transcriptase promoter mutation.
Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter.
[Clinical value of BRAF V600E in thyroid carcinoma and the effect of telomerase reverse transcriptase promoter mutations].
Thyroid Nodule
Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms.
Human telomerase reverse transcriptase expression in Diff-Quik-stained FNA samples from thyroid nodules.
Preoperative detection of TERT promoter and BRAFV600E mutations in papillary thyroid carcinoma in high-risk thyroid nodules.
Telomerase activity in fine needle aspiration biopsy samples: application to diagnosis of human thyroid carcinoma.
Thyroiditis
Detection and localization of chemokine gene expression in autoimmune thyroid disease.
Telomerase activity in benign and malignant thyroid tumors.
Thyroiditis, Autoimmune
Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension.
Telomerase activity in thyroid malignancy.
Tics
Predicting clinical outcome in feline oral squamous cell carcinoma: tumour initiating cells, telomeres and telomerase.
The effects of telomerase inhibition on prostate tumor-initiating cells.
Tongue Neoplasms
Effects of tea polyphenols on telomerase activity of a tongue cancer cell line: a preliminary study.
[Construction of antisense human tankyrase-1 RNA retroviral vector and its inhibition on tongue cancer cells]
[Effects of arsenic trioxideon the cell apoptosis and hTERT mRNA of human tongue cancer cells]
[Telomerase activity in rat tongue carcinogenesis]
[The experimental study on telomerase activity and expression of p53 and c-myc genes in tongue cancer]
Toxoplasmosis
Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii.
Changing patterns in the neuropathogenesis of HIV during the HAART era.
Triple Negative Breast Neoplasms
Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent ?-H2AX and telomerase regulation in triple-negative breast cancer.
Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532.
Trophoblastic Neoplasms
Estrogen and progesterone receptors and telomerase enzyme immunohistochemical detection in gestational trophoblastic tumors.
Telomerase activity and the subunit of telomerase in hydatidiform mole and their relationship with the development of postmolar tumor.
Telomerase activity in complete hydatidiform mole.
Tuberculosis
5-Arylaminouracil Derivatives as Potential Dual-Action Agents.
Antimycobacterial and HIV-1 Reverse Transcriptase Activity of Julianaceae and Clusiaceae Plant Species from Mexico.
Bioactive compounds from Lippia javanica and Hoslundia opposita.
Can an optimization/scoring procedure in ligand-protein docking be employed to probe drug-resistant mutations in proteins?
CYP2B6 genotype-directed dosing is required for optimal efavirenz exposure in children 3-36 months with HIV infection.
Differential expression of PE and PE_PGRS genes in Mycobacterium tuberculosis strains.
Dyslipidemia among HIV-infected Patients with tuberculosis taking once-daily nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in India.
Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.
Early virological response of zidovudine/lamivudine/abacavir for patients co-infected with HIV and tuberculosis in Uganda.
HIGH FREQUENCY GENETIC TRANSFORMATION OF CICHORIUM INTYBUS L. USING nptII GENE AS A SELECTIVE MARKER.
Higher Frequency of HIV-1 Drug Resistance and Increased Nucleoside Reverse Transcriptase Inhibitor Mutations among the HIV-1 Positive Antiretroviral Therapy-Naïve patients Coinfected With Mycobacterium tuberculosis Compared With Only HIV Infection in India.
Non nucleoside reverse transcriptase inhibitors, molecular docking studies and antitubercular activity of thiazolidin-4-one derivatives.
Patients presenting with AIDS in the HAART era: a collaborative cohort analysis.
Peripheral Neuropathy in HIV: An Analysis of Evidence-based Approaches.
Risk assessment of Soulatrolide and Mammea (A/BA+A/BB) coumarins from Calophyllum brasiliense by a toxicogenomic and toxicological approach.
Risk factors for tuberculosis after highly active antiretroviral treatment (HAART) initiation among HIV patients: A systematic review.
Toxicogenomic analysis of pharmacological active coumarins isolated from Calophyllum brasiliense.
[A study on the telomerase activity in lung cancer and its clinical significance.]
Tuberculosis, Pulmonary
Application of telomerase activity for screening of primary lung cancer in broncho-alveolar lavage fluid.
Tuberculin purified protein derivative up-regulates the telomerase activity of peripheral blood mononuclear cells from patients with pulmonary tuberculosis.
Tuberous Sclerosis
Pigmentary disorders of the eyes and skin.
Tumor Virus Infections
Fate of viral RNA of murine leukemia virus after infection.
Ureteral Neoplasms
Telomerase activity in human urothelial tumors.
Urethral Stricture
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Urinary Bladder Calculi
Detecting human bladder carcinoma cells in voided urine samples by assaying for the presence of telomerase activity.
Urinary Bladder Diseases
Diagnosis of bladder cancer using telomerase activity in voided urine.
Urinary Bladder Neoplasms
A highly sensitive and facile graphene oxide-based nucleic acid probe: Label-free detection of telomerase activity in cancer patient's urine using AIEgens.
A Highly Sensitive Catalytic Hairpin Assembly-Based Dynamic Light-Scattering Biosensors for Telomerase Detection in Bladder Cancer Diagnosis.
A portable dual-mode sensor based on a TiO2 nanotube membrane for the evaluation of telomerase activity.
A prospective evaluation of the diagnostic and potential prognostic utility of urinary human telomerase reverse transcriptase mRNA in patients with bladder cancer.
A study comparing various noninvasive methods of detecting bladder cancer in urine.
Accuracy of urine telomerase activity to detect bladder cancer in symptomatic patients.
Accurate urine telomerase test for detecting bladder cancer.
Activating Telomerase TERT Promoter Mutations and Their Application for the Detection of Bladder Cancer.
Antisense-mediated inhibition of survivin, hTERT and VEGF in bladder cancer cells in vitro and in vivo.
Application of targeted radiotherapy/gene therapy to bladder cancer cell lines.
Applications of telomerase in urologic oncology.
Assessment of DNA damage and telomerase activity in exfoliated urinary cells as sensitive and noninvasive biomarkers for early diagnosis of bladder cancer in ex-workers of a rubber tyres industry.
Bayesian bivariate meta-analysis of diagnostic test studies with interpretable priors.
BCG effects on telomerase activity in bladder cancer cell lines.
Bladder Cancer and Genetic Mutations.
Bladder cancer.
Chemosensitization of bladder cancer cell lines by human telomerase reverse transcriptase antisense treatment.
Clinical evaluation of human telomerase catalytic subunit in bladder washings from patients with bladder cancer.
Combined assay of CYFRA21-1, telomerase and vascular endothelial growth factor in the detection of bladder transitional cell carcinoma.
Comparative Study of NMP-22, Telomerase, and BTA in the Detection of Bladder Cancer.
Comparison of human telomerase reverse transcriptase messenger RNA and telomerase activity as urine markers for diagnosis of bladder carcinoma.
Comparison of human telomerase RNA and telomerase activity in urine for diagnosis of bladder cancer.
Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene- and targeted radiotherapy approach to bladder carcinoma.
Comparison of screening methods in the detection of bladder cancer.
Comparison of telomerase activity and matrix metalloproteinase-9 in voided urine and bladder wash samples as a useful diagnostic tool for bladder cancer.
Comparison of telomerase activity in bladder carcinoma and exfoliated cells collected in urine and bladder washings, using a quantitative assay.
Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer.
Construction of AIEgens-Based Bioprobe with Two Fluorescent Signals for Enhanced Monitor of Extracellular and Intracellular Telomerase Activity.
Current bladder tumor tests: does their projected utility fulfill clinical necessity?
Cytokeratin-20 reverse-transcriptase polymerase chain reaction as a new tool for the detection of circulating tumor cells in peripheral blood and bone marrow of bladder cancer patients.
Defining the role of NMP22 in bladder cancer surveillance.
Detection of human telomerase reverse transcriptase messenger RNA in voided urine samples as a useful diagnostic tool for bladder cancer.
Detection of human telomerase reverse transcriptase mRNA in urine of patients with bladder cancer: evaluation of an emerging tumor marker.
Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer.
Detection of telomerase activity in urine as a tool for noninvasive detection of recurrent bladder tumors is poor and cannot be improved by timing of sampling.
Detection of telomerase in urine by 3 methods: evaluation of diagnostic accuracy for bladder cancer.
Detection of the presence of catalytic subunit mRNA associated with telomerase gene in exfoliated urothelial cells from patients with bladder cancer.
Detection of Urothelial Bladder Cancer Based on Urine and Tissue Telomerase Activity Measured by Novel RT-TRAP-2PCR Method.
Diagnosis of bladder cancer using telomerase activity in voided urine.
Diagnostic Value of Telomerase Activity in Patients With Bladder Cancer: A Meta-Analysis of Diagnostic Test.
Diagnostic value of urinary molecular markers in bladder cancer.
Differential induction in telomerase activity among bladder cancer patients and controls on gamma-radiation.
Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors.
Editorial Comment from Dr Kurobe to Telomerase reverse transcriptase promoter mutation in tumorigenesis of bladder cancer: Evolutionary trajectory by algorithmic inference from cross-sectional data.
Editorial Comment from Dr Urabe to Telomerase reverse transcriptase promoter mutation in tumorigenesis of bladder cancer: Evolutionary trajectory by algorithmic inference from cross-sectional data.
Effects of combined siRNA-TR and -TERT on telomerase activity and growth of bladder transitional cell cancer BIU-87 cells.
Evaluation of the telomeric repeat amplification protocol (TRAP) assay for telomerase as a diagnostic modality in recurrent bladder cancer.
Evaluation of urinary human telomerase reverse transcriptase mRNA and scatter factor protein as urine markers for diagnosis of bladder cancer.
Expression of a recombinant vector of a mutant human telomerase reverse transcriptase gene in human bladder cancer cell line T24, and its clinical significance.
Expression of estrogen receptors-alpha and -beta in bladder cancer cell lines and human bladder tumor tissue.
Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer.
Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer.
Facile Probe Design: Fluorescent Amphiphilic Nucleic Acid Probes without Quencher Providing Telomerase Activity Imaging Inside Living Cells.
Frequency of TERT Promoter Mutations in Prostate Cancer.
Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway.
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Gene expression in the bladder carcinoma rat model.
Highly sensitive ratiometric fluorescent paper sensor for the urine assay of cancer.
hTERT cancer risk genotypes are associated with telomere length.
Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer.
Inhibition of telomerase with human telomerase reverse transcriptase antisense enhances tumor necrosis factor-alpha-induced apoptosis in bladder cancer cells.
Label-free, PCR-free chip-based detection of telomerase activity in bladder cancer cells.
Mad1 suppresses bladder cancer cell proliferation by inhibiting human telomerase reverse transcriptase transcription and telomerase activity.
Meta-analysis for diagnostic accuracy studies: a new statistical model using beta-binomial distributions and bivariate copulas.
Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients.
Molecular genetic evaluation of fluorescence diagnosis in bladder cancer.
Molecular genetics of bladder cancer: targets for diagnosis and therapy.
Molecular identification of telomerase reverse transcriptase (TERT) promotor mutations in primary and recurrent tumors of invasive and noninvasive urothelial bladder cancer.
Molecular markers and bladder carcinoma: Schistosomal and non-schistosomal.
Molecular markers and Schistosoma-associated bladder carcinoma: A systematic review and meta-analysis.
New diagnostic strategies in the detection and staging of bladder cancer.
New molecular markers for bladder cancer detection.
Non-invasive diagnosis of bladder cancer by detecting telomerase activity in human urine using hybridization chain reaction and dynamic light scattering.
Non-invasive diagnostic tests for bladder cancer: a review of the literature.
Non-radioactive measurement of telomerase activity in human bladder cancer, bladder washings, and in urine.
Performance characteristics of multiple urinary tumor markers and sample collection techniques in the detection of transitional cell carcinoma of the bladder.
Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis.
Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy.
Pretreatment levels of serum osteoprotegerin and p53 protein and urine telomerase as prognostic factors affecting survival in Egyptian bladder cancer patients.
Prospective evaluation of genetic abnormalities and telomerase expression in exfoliated urinary cells for bladder cancer detection.
Quantitative evaluation of telomerase subunits in urine as biomarkers for noninvasive detection of bladder cancer.
Quantitative measurement of telomerase reverse transcriptase (hTERT) mRNA in urothelial cell carcinomas.
Quantitative measurement of telomerase reverse transcriptase mRNA and chromosomal analysis of urine by M-FISH in the diagnosis and follow-up of bladder cancer.
Re: Yves Allorya, Willemien Beukers, Ana Sagrera, et al. Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome. Eur Urol 2014;65:360-6: Telomerase Expression and Stem Cells: Urologic Epithelial Perspective.
Real-time quantitative analysis for human telomerase reverse transcriptase mRNA and human telomerase RNA component mRNA expressions as markers for clinicopathologic parameters in urinary bladder cancer.
Real-Time, Quantitative Lighting-up Detection of Telomerase in Urines of Bladder Cancer Patients by AIEgens.
Recurrent TERT promoter mutations in urothelial carcinoma and potential clinical applications.
Relevance of urine telomerase in the diagnosis of bladder cancer.
Rs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis.
Screening and identification of specific markers for bladder transitional cell carcinoma from urine urothelial cells with suppressive subtractive hybridization and cDNA microarray.
Semi-quantitative analysis of telomerase activity in exfoliated human urothelial cells and bladder transitional cell carcinoma.
Sensitive and bidirectional detection of urine telomerase based on the four detection-color states of difunctional gold nanoparticle probe.
Sensitivity and specificity of NMP-22, telomerase, and BTA in the detection of human bladder cancer.
shRNA-targeted hTERT suppress cell proliferation of bladder cancer by inhibiting telomerase activity.
Strand displacement amplification-coupled dynamic light scattering method to detect urinary telomerase for non-invasive detection of bladder cancer.
Subsequential telomerase activity in exfoliated urinary cells detects recurrent disease in bladder cancer after transurethral resection.
Synthesizing AND gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells.
Synthetic Bax-Anti Bcl2 combination module actuated by super artificial hTERT promoter selectively inhibits malignant phenotypes of bladder cancer.
Synthetic miRNA sponges driven by mutant hTERT promoter selectively inhibit the progression of bladder cancer.
Synthetic regulatory RNAs selectively suppress the progression of bladder cancer.
Target-Driven Nanozyme Growth in TiO2 Nanochannels for Improving Selectivity in Electrochemical Biosensing.
Telomerase Activity Analysis In Urine Sediment for Bladder Cancer.
Telomerase activity as a potential marker in preneoplastic bladder lesions.
Telomerase activity detected by quantitative assay in bladder carcinoma and exfoliated cells in urine.
Telomerase activity in bilharzial bladder cancer. Prognostic implications.
Telomerase activity in bladder cancer tissue.
Telomerase activity in bladder cancer, bladder washings and in urine.
Telomerase activity in diagnosis of bladder cancer.
Telomerase activity in human bladder cancer.
Telomerase activity in human bladder tumors and bladder washing specimens.
Telomerase activity in human urothelial tumors.
Telomerase activity in malignant and benign bladder conditions.
Telomerase activity in solid transitional cell carcinoma, bladder washings, and voided urine.
Telomerase activity in urine after transurethral resection is not a predictive marker for recurrence of superficial bladder cancer.
Telomerase activity in urine after transurethral resection of superficial bladder cancer and early recurrence.
Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer.
Telomerase activity Simplification of assay and detection in bladder tumor and urinary exfoliated cells.
Telomerase activity, cytokeratin 20 and cytokeratin 19 in urine cells of bladder cancer patients.
Telomerase activity: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase and other novel approaches to bladder cancer detection.
Telomerase in bladder cancer: back to a better future?
Telomerase in human bladder cancer.
Telomerase in urological malignancy.
Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines.
Telomerase is upregulated in irreversible preneoplastic lesions during bladder carcinogenesis in rats.
Telomerase promoter mutations in cancer: an emerging molecular biomarker?
Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: a genomic and molecular study.
Telomerase reverse transcriptase mutation and the p53 pathway in T1 urinary bladder cancer.
Telomerase reverse transcriptase promoter mutation in tumorigenesis of bladder cancer: Evolutionary trajectory by algorithmic inference from cross-sectional data.
Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome.
Telomerase suppression initiates PML-dependent p53 activation to inhibit bladder cancer cell growth.
Telomerase targeted oligonucleotide thio-phosphoramidates in T24-luc bladder cancer cells.
Telomerase therapeutics: telomeres recognized as a DNA damage signal: commentary re: K. Kraemer et al., antisense-mediated hTERT inhibition specifically reduces the growth of human bladder cancer cells. Clin. Cancer Res., 9: 3794-3800, 2003.
Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes.
Telomerase: its clinical relevance in the diagnosis of bladder cancer.
Telomere instability in papillary bladder urothelial carcinomas: Comparison with grading and risk of recurrence.
TERT Promoter Mutation as a Potential Predictive Biomarker in BCG-Treated Bladder Cancer Patients.
The clinical significance of PINX1 expression in papillary thyroid carcinoma.
The current role of telomerase in the diagnosis of bladder cancer.
The molecular detection of circulating tumor cells in bladder cancer using telomerase activity.
The role of telomerase reverse transcriptase (TERT) promoter mutations in prognosis in bladder cancer.
The simultaneous use of telomerase, cytokeratin 20 and CD4 for bladder cancer detection in urine.
This month in investigative urology. Expression of the catalytic subunit associated with telomerase gene in human urinary bladder cancer.
Treatment of bladder cancer cells in vitro and in vivo with 2-5A antisense telomerase RNA.
TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer.
Tumor markers in the detection of recurrent transitional cell carcinoma of the bladder: a brief review.
Tumor markers in the diagnosis of primary bladder cancer. A systematic review.
Urinary markers of malignancy.
Urinary telomerase and its possible role as a marker for bladder cancer.
Urine telomerase activity for the detection of bladder cancer in females.
Urine telomerase activity for the diagnosis of bladder cancer.
Urine telomerase and bladder cancer detection.
Urine telomerase for diagnosis and surveillance of bladder cancer.
Urine telomerase: an important marker in the diagnosis of bladder cancer.
Urine: beyond cytology for detection of malignancy.
[Detection of telomerase activity by semi-quantitative and in situ assays and quantification of hTERT expression in bladder carcinomas]
[Development of noninvasive bladder cancer diagnosis on basis of telomerase and it's subunits hTERT and hTR detection].
[Diagnosis of human bladder cancer by detecting the telomerase activity in exfoliated urothelial cells]
[Effect of hTERT antisense oligodeoxynucleotide on telomerase activity in bladder cancer cells in vitro.]
[Effects of combining siRNA-TR and TERT upon telomerase activity and in vitro growth inhibition in transitional cancer of bladder BIU-87 cell line]
[Expression of telomerase genes in human tumors]
[Molecular biology in bladder cancer]
[Prospects for molecular research in urological oncology: bladder cancer]
[Quantitative analysis of telomerase activity in exfoliated urothelial cells for the diagnosis of bladder carcinoma]
[Significance of a simple assay of urine telomerase activity for the detection of bladder cancer].
[Telomerase activity and cellular apoptosis of bladder cancers]
[Telomerase activity as marker of superficial tumor of the bladder]
[Telomerase activity in bladder cancer tissues]
[Telomerase activity: a molecular marker for early diagnosis of bladder tumor]
[The role of telomerase activity in non-invasive diagnostics of bladder cancer].
Urinary Calculi
Diagnosis of bladder cancer using telomerase activity in voided urine.
Urinary Tract Infections
Diagnosis of bladder cancer using telomerase activity in voided urine.
Urogenital Diseases
Quantitative evaluation of telomerase subunits in urine as biomarkers for noninvasive detection of bladder cancer.
Urogenital Neoplasms
hTERT, hTR and TERT promoter mutations as markers for urological cancers detection: A systematic review.
Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: a genomic and molecular study.
Urologic Diseases
Telomerase activity in diagnosis of bladder cancer.
Telomerase activity in solid transitional cell carcinoma, bladder washings, and voided urine.
Urologic Neoplasms
[Prostate-specific antigen and telomerase in prostatic cancers]
Uterine Cervical Diseases
Gain of the human telomerase RNA gene TERC at 3q26 is strongly associated with cervical intraepithelial neoplasia and carcinoma.
Uterine Cervical Dysplasia
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.
Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer.
Uterine Cervical Neoplasms
2-5A antisense therapy directed against human telomerase RNA inhibits telomerase activity and induces apoptosis without telomere impairment in cervical cancer cells.
A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide.
A postulated role of p130 in telomere maintenance by human papillomavirus oncoprotein E7.
Accuracy of telomerase in cervical lesions: a systematic review.
Activin inhibits telomerase activity in cancer.
Amplification of TERT and TERC genes in cervical intraepithelial neoplasia and cervical cancer.
Amplification of the telomerase RNA component gene in the process of human esophageal carcinogenesis.
An initiative to assess the quality of Tanzanian cervical cancer specimens for HPV and telomerase detection.
Anti-carcinogenic effects of the phenolic-rich extract from abnormal Savda Munziq in association with its cytotoxicity, apoptosis-inducing properties and telomerase activity in human cervical cancer cells (SiHa).
Application of telomerase assay for the screening of cervical lesions.
Artemisinin Represses Telomerase Subunits and Induces Apoptosis in HPV-39 Infected Human Cervical Cancer Cells.
Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus.
Bone morphogenetic protein-7 inhibits telomerase activity, telomere maintenance, and cervical tumor growth.
Can Genomic Amplification of Human Telomerase Gene and C-MYC in Liquid-Based Cytological Specimens Be Used as a Method for Opportunistic Cervical Cancer Screening?
Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer.
Cytoplasmic poly(A) binding proteins regulate telomerase activity and cell growth in human papillomavirus 16 E6 expressing keratinocytes.
Detection of human telomerase RNA gene in cervical cancer and precancerous lesions: comparison with cytological and human papillomavirus DNA test findings.
Detention of HPV L1 Capsid Protein and hTERC Gene in Screening of Cervical Cancer.
Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions.
Early growth response-1 mediates downregulation of telomerase in cervical cancer.
Effect of daidzein on cell growth, cell cycle, and telomerase activity of human cervical cancer in vitro.
Efficient Inhibition of Human Telomerase Reverse Transcriptase Expression by RNA Interference Sensitizes Cancer Cells to Ionizing Radiation and Chemotherapy.
Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy.
Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancer.
Evaluation of serum human telomerase reverse transcriptase as a novel marker for cervical cancer.
Expression of HPV-16 E6 Protein and p53 Inactivation Increases the Uterine Cervical Cancer Invasion.
Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.
Gain of human telomerase RNA gene is associated with progression of cervical intraepithelial neoplasia grade I or II.
Gene expression profiling to identify markers associated with deregulated hTERT in HPV-transformed keratinocytes and cervical cancer.
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.
Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer.
GRIM-19 Restores Cervical Cancer Cell Senescence by Repressing hTERT Transcription.
HIF-1-mediated activation of telomerase in cervical cancer cells.
Highly Sensitive Telomerase Assay Insusceptible to Telomerase and Polymerase Chain Reaction Inhibitors for Cervical Cancer Screening Using Scraped Cells.
hTERT is a critical determinant of telomerase activity in renal-cell carcinoma.
hTERT Protein Expression in Cytoplasm and Nucleus and its Association With HPV Infection in Patients With Cervical Cancer.
Human papillomavirus and human telomerase RNA component gene in cervical cancer progression.
Human telomerase reverse transcriptase regulates vascular endothelial growth factor expression via human papillomavirus oncogene E7 in HPV-18-positive cervical cancer cells.
Human telomerase RNA gene amplification detection increases the specificity of cervical intraepithelial neoplasia screening.
IFN-gamma/IRF-1-induced p27kip1 down-regulates telomerase activity and human telomerase reverse transcriptase expression in human cervical cancer.
Immunohistochemical expression of ubiquitin and telomerase in cervical cancer.
Impact of modulation of telomerase and cancer stem-cell marker OCT4 axis in cervical cancer pathogenesis with underlying HPV16 infection.
Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice.
Inhibition of telomerase enhances apoptosis induced by sodium butyrate via mitochondrial pathway.
Inhibition of telomerase RNA (hTR) in cervical cancer by adenovirus-delivered siRNA.
Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance.
Investigating the Effects of RBBP6 Gene Expression on Telomerase Activity in Cervical Cancer Cells.
Isothiocyanates sensitize the effect of chemotherapeutic drugs via modulation of protein kinase C and telomerase in cervical cancer cells.
Kaempferol increases apoptosis in human cervical cancer HeLa cells via PI3K/AKT and telomerase pathways.
Knockdown of hTERT by siRNA inhibits cervical cancer cell growth in vitro and in vivo.
Knockdown of human telomerase reverse transcriptase induces apoptosis in cervical cancer cell line.
Lymph node metastases, not human telomerase reverse transcriptase or p53 proteins, as the strongest prognostic factor for survival in early stage cervical cancer.
Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer.
MiR-21-5p, miR-34a, and human telomerase RNA component as surrogate markers for cervical cancer progression.
NFX1-123 is highly expressed in cervical cancer and increases growth and telomerase activity in HPV 16E6 expressing cells.
PIF1 Affects the Proliferation and Apoptosis of Cervical Cancer Cells by Influencing TERT.
PinX1, a novel target gene of p53, is suppressed by HPV16 E6 in cervical cancer cells.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Profile of POT1 as telomerase shelterin component discriminatesbetween cervical cancer and normal cervical cells.
Protein kinase C modulates telomerase activity in human cervical cancer cells.
Role of Cancer Stem Cell, Apoptotic Factor, DNA Repair, and Telomerase Toward Radiation Therapy Response in Stage IIIB Cervical Cancer.
Semiquantitative analysis of telomerase activity in cervical cancer and precancerous lesions.
Serum tumor markers for detection of hepatocellular carcinoma.
Significance of human telomerase RNA gene amplification detection for cervical cancer screening.
siRNA-mediated Inhibition of hTERC Enhances Radiosensitivity of Cervical Cancer.
STRATEGIES OF TREATING CANCER BY CYTOKINE REGULATION OF CHROMOSOME END REMODELLING.
Suppression of telomerase activity and arrest at G1 phase in human cervical cancer HeLa cells by all-trans retinoic acid.
Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis.
Telomerase activation in cervical cancer.
Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer.
Telomerase activity and human papillomavirus (HPV) infection in human uterine cervical cancers and cervical smears.
Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smear.
Telomerase activity as a tumor marker in Indian women with cervical intraepithelial neoplasia and cervical cancer.
Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer.
Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA.
Telomerase activity in body cavity fluid and peritoneal washings in uterine and ovarian cancer.
Telomerase activity in cervical cancer is quantitatively distinct from that in its precursor lesions.
Telomerase activity in cervical intraepithelial neoplasia.
Telomerase activity in gynecological tumors.
Telomerase activity in high-grade cervical lesions is associated with allelic imbalance at 6Q14-22.
Telomerase and the process of cervical carcinogenesis.
Telomerase assay and HPV 16/18 typing as adjunct to conventional cytological cervical cancer screening.
Telomerase in (pre)neoplastic cervical disease.
Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer.
Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line.
Telomerase, cervical cancer, and human papillomavirus.
Telomerase, p53 and human papillomavirus infection in the uterine cervix.
Telomerase-A molecular marker for cervical cancer screening.
The tea polyphenol, (-)-epigallocatechin gallate effects on growth, apoptosis, and telomerase activity in cervical cell lines.
Upregulation of telomerase (hTERT) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus, virus persistence, or disease outcome in cervical cancer.
Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity.
[Cloning of alternative isoforms of the catalytic subunit of the human thelomerase (htert)].
[Combination of antisense human telomerase RNA and antisense human telomerase catalytic subunit inhibits cervical cancer Hela cells growth]
[Expression of human telomerase reverse transcriptase in cervix cancer and its significance]
[Study on the correlation between the different papillomavirus type and telomerase in cervical cancer]
[Telomerase activity in cervical cancer and its precursor lesion]
[Telomerase activity in cervical intraepithelial neoplasia]
Uterine Cervicitis
Telomerase activity in cervical intraepithelial neoplasia.
[Telomerase activity in cervical cancer and its precursor lesion]
Uterine Neoplasms
Implications of telomeres and telomerase in endometrial pathology.
[Telomerase activity in the uterine cervix and the uterine body]
[Telomerase activity of uterine cancer examined by telomeric repeat amplification protocol assay]
Uveitis
Molecular mimicry between a uveitopathogenic site of S-antigen and viral peptides. Induction of experimental autoimmune uveitis in Lewis rats.
Vaccinia
A chimeric avian retrovirus containing the influenza virus hemagglutinin gene has an expanded host range.
A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation.
Assembly of the matrix protein of simian immunodeficiency virus into virus-like particles.
Cell line-dependent release of HIV-like gag particles after infection of mammalian cells with recombinant vaccinia viruses.
Cellular motor protein KIF-4 associates with retroviral Gag.
Clustered epitopes within the Gag-Pol fusion protein DNA vaccine enhance immune responses and protection against challenge with recombinant vaccinia viruses expressing HIV-1 Gag and Pol antigens.
Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV.
Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime/recombinant modified vaccinia virus Ankara vaccine.
Cross-protection in NYVAC-HIV-1-immunized/HIV-2-challenged but not in NYVAC-HIV-2-immunized/SHIV-challenged rhesus macaques.
Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with modified vaccinia virus Ankara.
Enhancement of cellular and humoral immune responses to human immunodeficiency virus type 1 Gag and Pol by a G/P-92 fusion protein expressing highly immunogenic Gag p17/p24 and Pol p51 antigens.
Expression and processing of human immunodeficiency virus type 1 gag and pol genes by cells infected with a recombinant vaccinia virus.
Generation of transduction-competent retroviral vectors by infection with a single hybrid vaccinia virus.
HIV-2 viral protein X association with the GAG p27 capsid protein.
Human immunodeficiency virus type 1 Vif-derived peptides inhibit the viral protease and arrest virus production.
Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.
Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge.
Immunization with recombinant modified vaccinia virus Ankara can modify mucosal simian immunodeficiency virus infection and delay disease progression in macaques.
Improved survival in rhesus macaques immunized with modified vaccinia virus Ankara recombinants expressing simian immunodeficiency virus envelope correlates with reduction in memory CD4+ T-cell loss and higher titers of neutralizing antibody.
Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity.
Lower levels of gamma interferon expressed by a pseudotyped single-cycle simian immunodeficiency virus enhance immunogenicity in rats.
Microarray profiling of antibody responses against simian-human immunodeficiency virus: postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen.
Morphogenesis of recombinant HIV-2 gag core particles.
Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge.
Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component.
Oral Immunization with Recombinant Vaccinia Virus Prime and Intramuscular Protein Boost Provides Protection against Intrarectal Simian-Human Immunodeficiency Virus Challenge in Macaques.
Phosphorylation of HIV-1 gag proteins by protein kinase C.
Processing, assembly, and immunogenicity of human immunodeficiency virus core antigens expressed by recombinant vaccinia virus.
Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination.
Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses.
Rhesus immune responses to SIV Gag expressed by recombinant BCG vectors are independent from pre-existing mycobacterial immunity.
Role of the gag and pol genes of human immunodeficiency virus in the morphogenesis and maturation of retrovirus-like particles expressed by recombinant vaccinia virus: an ultrastructural study.
Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV-infected rhesus monkeys undergoing antiretroviral therapy.
Variable proteolytic cleavage of gag precursor expressed after infection of several cell lines with an HIV-2 gag-pol recombinant vaccinia virus.
[Expression of human immunodeficiency virus gag antigens and formation of virus-like particles in a cell culture, infected with recombinant vaccinia virus strains (an electron-microscopic study)]
[Interaction of gag polyprotein-precursors p55 and p48 with p160gag-pol during formation of virus-like particles of HIV-1 with recombinant strains of vaccinia virus]
Varicocele
Role of testicular tissue telomerase assay for the prediction of the presence of testicular spermatozoa in azoospermic men with varicoceles, pre- and post-varicocelectomy.
Vascular Diseases
Evidence for Telomerase Activation in VSMCs Exposed to Hyperglycemic and Hyperhomocysteinemic Conditions.
Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes.
Vascular System Injuries
Activation of peroxisome proliferator-activated receptor gamma suppresses telomerase activity in vascular smooth muscle cells.
Nuclear Factor {kappa}B-Mediated Transactivation of Telomerase Prevents Intimal Smooth Muscle Cell From Replicative Senescence During Vascular Repair.
Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension.
The PPARalpha/p16INK4a pathway inhibits vascular smooth muscle cell proliferation by repressing cell cycle-dependent telomerase activation.
Vesicular Stomatitis
A systematic review of inhaled intranasal therapy for central nervous system neoplasms: an emerging therapeutic option.
Development and characterization of a minimal inducible packaging cell line for simian immunodeficiency virus-based lentiviral vectors.
Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus.
Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma.
Toward the development of a single-round infection assay based on EGFP reporting for anti-HIV-1 drug discovery.
Transduction of Schistosoma japonicum schistosomules with vesicular stomatitis virus glycoprotein pseudotyped murine leukemia retrovirus and expression of reporter human telomerase reverse transcriptase in the transgenic schistosomes.
VSV-G pseudotyped, MuLV-based, semi-replication-competent retrovirus for cancer treatment.
Vipoma
Telomerase activity in pancreatic endocrine tumors.
Viremia
Bluetongue virus detection: a safer reverse-transcriptase polymerase chain reaction for prediction of viremia in sheep.
Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV.
Immune response against porcine reproductive and respiratory syndrome virus during acute and chronic infection.
Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge.
Improved survival in rhesus macaques immunized with modified vaccinia virus Ankara recombinants expressing simian immunodeficiency virus envelope correlates with reduction in memory CD4+ T-cell loss and higher titers of neutralizing antibody.
Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis.
Long-term follow-up of patients taking tenofovir DF with low-level HIV-1 viremia and the K65R substitution in HIV-1 RT.
Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.
Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients.
Phenotypic Coreceptor Tropism in Perinatally HIV-infected Youth Failing Antiretroviral Therapy.
Prevalence of drug-resistant HIV-1 in rural areas of Hubei province in the People's Republic of China.
The risk of polyomavirus-associated graft nephropathy is increased by a combined suppression of CD8 and CD4 cell-dependent immune effects.
Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV-infected rhesus monkeys undergoing antiretroviral therapy.
Treatment Switch to Dolutegravir With 2 Nucleoside Reverse-Transcriptase Inhibitors (NRTI) in Comparison to Continuation With Protease Inhibitor/Ritonavir Among Patients With Human Immunodeficiency Virus at Risk for Prior NRTI Resistance: A Cohort Analysis of Real-World Data.
Viral dynamics of early HIV infection in neonatal macaques after oral exposure to HIV-2287: an animal model with implications for maternal-neonatal HIV transmission.
Viremia and drug resistance among HIV-1 patients on antiretroviral treatment: a cross-sectional study in Soweto, South Africa.
Viremia, resuppression, and time to resistance in human immunodeficiency virus (HIV) subtype C during first-line antiretroviral therapy in South Africa.
Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy.
Virus Diseases
A new Akirin1 gene in turbot (Scophthalmus maximus): Molecular cloning, characterization and expression analysis in response to bacterial and viral immunological challenge.
Active fulminant myocarditis characterized by T-lymphocytes expressing the gamma-delta T-cell receptor: a new disease entity?
Approved Antiviral Drugs over the Past 50 Years.
Bovine herpesvirus type 1 (BHV-1) up-regulates telomerase activity in MDBK cells.
Classification of COVID-19 by Compressed Chest CT Image through Deep Learning on a Large Patients Cohort.
Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China.
Comparative measurement of FeLV load in hemolymphatic tissues of cats with hematologic cytopenias.
Cooperative effect of gag proteins p12 and capsid during early events of murine leukemia virus replication.
Curious Discoveries in Antiviral Drug Development: The Role of Serendipity.
Delivery of double-stranded DNA thioaptamers into HIV-1 infected cells for antiviral activity.
Differential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.
Differential levels of mRNAs for cytokines, the interleukin-2 receptor and class II DR/DQ genes in ovine interstitial pneumonia induced by maedi visna virus infection.
Efavirenz induces neuronal autophagy and mitochondrial alterations.
Effect of productive in vitro human immunodeficiency virus or simian immunodeficiency virus infection on telomerase activity in lymphoid and nonlymphoid cells.
Epidemiology of cases of H5N1 virus infection in Indonesia, July 2005-June 2006.
Epidemiology of Influenza in Fars Province, Southern Iran; a Population-Based Study (2015-2019).
Evaluation of reverse-transcriptase PCR as a diagnostic tool to confirm Japanese encephalitis virus infection.
H1N1 2009 influenza virus infection during pregnancy in the USA.
Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase.
Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells.
HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.
Huwe1, a novel cellular interactor of Gag-Pol through integrase binding, negatively influences HIV-1 infectivity.
IFN-? Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling.
In vitro antiretroviral activity and in vitro toxicity profile of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus infection.
Influence of human granulocyte-macrophage colony stimulating factor/interleukin-3 fusion protein (PIXY321) on the hematopoietic toxicity associated with anti-viral drugs (zidovudine and didanosine) in vitro using normal human marrow cells.
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Measuring Telomerase Activity in Senescent Human T Cells Upon Genetic Modification.
Modulation of telomerase activity, bTERT and c-Myc induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin during Bovine Herpesvirus 1 infection in MDBK cells.
Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component.
Novel swine-origin influenza A (H1N1) viral encephalitis.
p53 and hTERT determine sensitivity to viral apoptosis.
Post-exposure chemoprophylaxis (PECP) against SIV infection of macaques as a model for protection from HIV infection.
Profile of Leukocyte-Endothelial Cell Interactions Induced in Venules and Arterioles by Nucleoside Reverse-Transcriptase Inhibitors In Vivo.
Proteolytic processing of particle-associated retroviral polyproteins by homologous and heterologous viral proteinases.
Reduced dNTP Binding Affinity of 3TC-resistant M184I HIV-1 Reverse Transcriptase Variants Responsible for Viral Infection Failure in Macrophage.
Safety of rilpivirine plus nucleoside reverse-transcriptase inhibitors in HIV-infected Taiwanese with a higher prevalence of hepatitis virus infection.
Significance of viral infections detected by reverse-transcriptase - multiplex PCR on hospital-related outcomes in acute exacerbations of chronic obstructive pulmonary disease.
Similar risk of renal events among patients treated with tenofovir or entecavir for chronic hepatitis B.
Structural basis for the D-stereoselectivity of human DNA polymerase ?.
Synthesis of Pyrazine-1,3-thiazine Hybrid Analogues as Antiviral Agent Against HIV-1, Influenza A (H1N1), Enterovirus 71 (EV71), and Coxsackievirus B3 (CVB3).
Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy.
Telomerase Biology Associations offer Keys to Cancer and Aging Therapeutics.
Tenofovir-associated renal dysfunction in clinical practice: An observational cohort from western India.
The antiretroviral 2',3'-dideoxycytidine causes mitochondrial dysfunction in proliferating and differentiated HepaRG human cell cultures.
The epithelium in idiopathic pulmonary fibrosis: breaking the barrier.
The Telomerase Inhibitor MST-312 Interferes with Multiple Steps in the Herpes Simplex Virus Life Cycle.
Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells.
Uracil-Containing Heterodimers of a New Type: Synthesis and Study of Their Anti-Viral Properties.
Variations of telomerase activity in cultured mouse fibroblasts upon proliferation of polyomavirus.
[The inhibitory effect of antisense adenovirus vector of telomerase on telomerase activity in breast cancer cells MCF-7]
Visna
Characterization of the nucleic acid product of the visna virus RNA dependent DNA polymerase.
Differential levels of mRNAs for cytokines, the interleukin-2 receptor and class II DR/DQ genes in ovine interstitial pneumonia induced by maedi visna virus infection.
Evidence for interference, coinfections, and intertypic virus enhancement of infection by ovine-caprine lentiviruses.
Evidence for two forms of RNA-dependent DNA polymerase in Visna virus.
Genetic variation among lentiviruses: homology between visna virus and caprine arthritis-encephalitis virus is confined to the 5' gag-pol region and a small portion of the env gene.
Visna virus: a slow virus with an RNA dependent DNA polymerase.
[Immunologic aspects of preparation of antiserum to the reverse transcriptase from avian myeloblastosis virus]
Vitamin B 12 Deficiency
Antiretroviral use and other risks for HIV-associated neuropathies in an international cohort.
Vitiligo
Assessment of telomerase activity in nonsegmental vitiligo tissue: a pilot study.
Vitreoretinopathy, Proliferative
The anti-proliferative effect of inhibitor of telomerase on cultured retinal pigment epithelial cells.
von Hippel-Lindau Disease
Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.
Telomerase activity in pancreatic endocrine tumors.
Vulvar Neoplasms
Telomerase activity in gynecological tumors.
Vulvar Vestibulitis
Telomerase activity in HPV-associated vulvar vestibulitis.
Waardenburg Syndrome
Pigmentary disorders of the eyes and skin.
Warts
Approved Antiviral Drugs over the Past 50 Years.
Telomerase activity in melanoma and non-melanoma skin cancer.
Werner Syndrome
Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients.
Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Evidence that a RecQ helicase slows senescence by resolving recombining telomeres.
Influence of aging and cell senescence on telomerase activity in keratinocytes.
Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains.
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts.
Telomerase protects werner syndrome lineage-specific stem cells from premature aging.
The effect of 2-deoxy-D-glucose on Werner syndrome RecQ helicase gene.
The effect of resveratrol on the werner syndrome RecQ helicase gene and telomerase activity.
WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts.
West Nile Fever
Fatal hemorrhagic fever caused by West Nile virus in the United States.
Wilms Tumor
Combinatorial molecular marker assays of WT1, survivin, and TERT at initial diagnosis of adult acute myeloid leukemia.
Expression of the RNA component of telomerase in Wilms tumor and nephrogenic rest recapitulates renal embryogenesis.
Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.
High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms' tumor.
High telomerase RNA expression level is an adverse prognostic factor for favorable-histology Wilms' tumor.
P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma.
T cell-based targeted immunotherapies for patients with multiple myeloma.
Telomerase reverse transcriptase catalytic subunit expression and proliferation index in Wilms tumor.
The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene.
Wilms' tumour 1 can suppress hTERT gene expression and telomerase activity in clear cell renal cell carcinoma via multiple pathways.
Xeroderma Pigmentosum
DNA repair proteins and telomerase reverse transcriptase in the cochlear lateral wall of cisplatin-treated rats.
Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins.
RNA dependent DNA polymerase in cells of xeroderma pigmentosum.
Telomere Length and Telomerase Activity Impact the UV Sensitivity Syndrome Xeroderma Pigmentosum C.
Xerostomia
Antiretroviral therapy: effects on orofacial health and health care.
Yellow Fever
Development of multiplex real-time reverse-transcriptase polymerase chain reaction assay for simultaneous detection of Zika, dengue, yellow fever, and chikungunya viruses in a single tube.
Zika Virus Infection
Pregnancy outcomes after maternal Zika virus infection in a non-endemic region: prospective cohort study.