BRENDA Home
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments3-Methylbutanoate, 2-methylbutanoate, pentanoate, butanoate and propanoate can also act as acceptors (cf. EC 2.7.2.7 butyrate kinase).
The enzyme appears in viruses and cellular organisms
Synonyms
isobutyrate kinase,
morePlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
branched-chain fatty acid kinase
-
-
-
-
isobutyrate kinase
-
-
-
-
kinase (phosphorylating), branched-chain fatty acid
-
-
-
-
kinase, branched-chain fatty acid (phosphorylating)
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + 2-methylpropanoate = ADP + 2-methylpropanoyl phosphate
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
phospho group transfer
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP:branched-chain-fatty-acid 1-phosphotransferase
3-Methylbutanoate, 2-methylbutanoate, pentanoate, butanoate and propanoate can also act as acceptors (cf. EC 2.7.2.7 butyrate kinase).
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + 2-methylbutanoate
ADP + 2-methylbutanoyl phosphate
-
-
-
?
ATP + butanoate
ADP + butanoyl phosphate
-
-
-
-
?
ATP + isobutanoate
ADP + isobutanoyl phosphate
ATP + isopentanoate
ADP + isopentanoyl phosphate
-
-
-
-
?
ATP + pentanoate
ADP + pentanoyl phosphate
-
-
-
-
?
ATP + propionate
ADP + propanoyl phosphate
-
-
-
-
?
CTP + isobutanoate
CDP + isobutanoyl phosphate
-
103% of the activity with ATP
-
-
?
GTP + isobutanoate
GDP + isobutanoyl phosphate
-
70% of the activity with ATP
-
-
?
ITP + isobutanoate
IDP + isobutanoyl phosphate
-
68% of the activity with ATP
-
-
?
additional information
?
-
ATP + isobutanoate
ADP + isobutanoyl phosphate
-
-
-
-
?
ATP + isobutanoate
ADP + isobutanoyl phosphate
-
-
-
-
?
additional information
?
-
-
no actrivity with acetate
-
-
?
additional information
?
-
-
involved in catabolism of branched-chain amino acids
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
?
-
-
involved in catabolism of branched-chain amino acids
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Co2+
-
65% of the activity with Mn2+
Cu2+
-
58% of the activity with Mn2+
Mg2+
-
96% of the activity with Mn2+
Mn2+
-
divalent cation required, highest activity with Mn2+
Zn2+
-
42% of the activity with Mn2+
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
10.8
2-methylbutyrate
-
pH 7.5, 30°C
16.9
Butyrate
-
pH 7.5, 30°C
4.3
Isobutyrate
-
pH 7.5, 30°C
9.5
Isovalerate
-
pH 7.5, 30°C
14.3
propionate
-
pH 7.5, 30°C
12.5
valerate
-
pH 7.5, 30°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
6 - 8.5
-
more than 80% of maximal activity at pH 6.0 and 8.5
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
MA-2
-
-
brenda
MA-2
-
-
brenda
-
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
380000
-
dynamic light scattering
43000
-
crystallization data, 8 * 43000, calculated for recombinant protein with His6-tag
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
octamer
-
crystallization data, 8 * 43000, calculated for recombinant protein with His6-tag
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
recombinant protein with His6-tag
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
45
-
30 min, 25% loss of activity
60
-
30 min, complete loss of activity
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
complete loss of activity if filtered through columns of Sephacryl S-300 at room temperature
-
dialysis, 6 h at 5°C, significant loss of activity
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-50°C, crude cell extract stable for 2 months
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Harwood, C.S.; Canale-Parola, E.
Properties of acetate kinase isozymes and a branched-chain fatty acid kinase from a spirochete
J. Bacteriol.
152
246-254
1982
Spirochaeta sp., Spirochaeta sp. MA-2
brenda
Diao, J.; Cooper, D.R.; Sanders, D.A.; Hasson, M.S.
Crystallization of butyrate kinase 2 from Thermotoga maritima mediated by vapor diffusion of acetic acid
Acta Crystallogr. Sect. D
59
1100-1102
2003
Thermotoga maritima
brenda
Select items on the left to see more content.
html completed
2.7.2.14 branched-chain-fatty-acid kinase
top
