Reference on EC 2.7.1.67 - 1-phosphatidylinositol 4-kinase and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Walker, D.H.; Dougherty, N.; Pike, L.J.
Purification and characterization of a phosphatidylinositol kinase from A431 cells
Biochemistry
27
6504-6511
1988
Homo sapiens
Vogel, S.; Hoppe, J.
Polyamines stimulate the phosphorylation of phosphatidylinositol in membranes from A431 cells
Eur. J. Biochem.
154
253-257
1986
Homo sapiens
Graziani, A.; Ling, L.E.; Endemann, G.; Carpenter, C.L.; Cantley, L.C.
Purification and characterization of human erythrocyte phosphatidylinositol 4-kinase. Phosphatidylinositol 4-kinase and phosphatidylinositol 3-monophosphate 4-kinase are distinct enzymes
Biochem. J.
284
39-45
1992
Homo sapiens
-
Nishioka, H.; Sawa, T.; Hamada, M.; Shimura, N.; Imoto, M.; Umezawa, K.
Inhibition of phosphatidylinositol kinase by toyocamycin
J. Antibiot.
43
1586-1589
1990
Homo sapiens
Suga, K.; Kambayashi, J.; Tsujinaka, T.; Sakon, M.; Mori, T.
Properties of phosphatidylinositol kinase of human platelets
Biochem. Int.
15
769-777
1987
Homo sapiens
Buckley, J.T.
Properties of human erythrocyte phosphatidylinositol kinase and inhibition by adenosine, ADP and related compounds
Biochim. Biophys. Acta
498
1-9
1977
Homo sapiens
Jenkins, G.H.; Subrahmanyam, G.; Anderson, R.A.
Purification and reconstitution of phosphatidylinositol 4-kinase from human erythrocytes
Biochim. Biophys. Acta
1080
11-18
1991
Homo sapiens
Wetzker, R.; Klinger, R.; Hsuan, J.; Fry, M.J.; Kauffmann-Zeh, A.; Mller, E.; Frunder, H.; Waterfield, M.
Purification and characterization of phosphatidylinositol 4-kinase from human erythrocyte membranes
Eur. J. Biochem.
200
179-185
1991
Homo sapiens
Kanoh, H.; Banno, Y.; Hirata, M.; Nozawa, Y.
Partial purification and characterization of phosphatidylinositol kinases from human platelets
Biochim. Biophys. Acta
1046
120-126
1990
Homo sapiens
Heilmeyer, L.Jr.; Vereb, G.Jr.; Vereb, G.; Kakuk, A.; Szivak, I.
Mammalian phosphatidylinositol 4-kinases
IUBMB Life
55
59-65
2003
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Suer, S.; Sickmann, A.; Meyer, H.E.; Herberg, F.W.; Heilmeyer, L.M., Jr.
Human phosphatidylinositol 4-kinase isoform PI4K92. Expression of the recombinant enzyme and determination of multiple phosphorylation sites
Eur. J. Biochem.
268
2099-2106
2001
Homo sapiens (Q9UBF8), Homo sapiens
Waugh, M.G.; Minogue, S.; Anderson, J.S.; Balinger, A.; Blumenkrantz, D.; Calnan, D.P.; Cramer, R.; Hsuan, J.J.
Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum
Biochem. J.
373
57-63
2003
Homo sapiens
Wei, Y.J.; Sun, H.Q.; Yamamoto, M.; Wlodarski, P.; Kunii, K.; Martinez, M.; Barylko, B.; Albanesi, J.P.; Yin, H.L.
Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP
J. Biol. Chem.
277
46586-46593
2002
Homo sapiens (Q8TCG2)
Balla, A.; Tuymetova, G.; Barshishat, M.; Geiszt, M.; Balla, T.
Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments
J. Biol. Chem.
277
20041-20050
2002
Homo sapiens (Q8TCG2)
Prajda, N.; Singhal, R.L.; Yeh, Y.A.; Olah, E.; Look, K.Y.; Weber, G.
Linkage of reduction in 1-phosphatidylinositol 4-kinase activity and inositol 1,4,5-trisphosphate concentration in human ovarian carcinoma cells treated with quercetin
Life Sci.
56
1587-1593
1995
Homo sapiens
Waugh, M.G.; Minogue, S.; Blumenkrantz, D.; Anderson, J.S.; Hsuan, J.J.
Identification and characterization of differentially active pools of type IIalpha phosphatidylinositol 4-kinase activity in unstimulated A431 cells
Biochem. J.
376
497-503
2003
Homo sapiens
Srivastava, R.; Ratheesh, A.; Gude, R.K.; Rao, K.V.K.; Panda, D.; Subrahmanyam, G.
Resveratrol inhibits type II phosphatidylinositol 4-kinase: A key component in pathways of phosphoinositide turn over
Biochem. Pharmacol.
70
1048-1055
2005
Homo sapiens (Q8TCG2)
Souza, M.S.; Magnarelli de Potas, G.; Pechen de D'Angelo, A.M.
Organophosphorous and organochlorine pesticides affect human placental phosphoinositides metabolism and PI-4 kinase activity
J. Biochem. Mol. Toxicol.
18
30-36
2004
Homo sapiens
Wu, B.; Kitagawa, K.; Zhang, N.Y.; Liu, B.; Inagaki, C.
Pathophysiological concentrations of amyloid beta proteins directly inhibit rat brain and recombinant human type II phosphatidylinositol 4-kinase activity
J. Neurochem.
91
1164-1170
2004
Homo sapiens
Balla, A.; Tuymetova, G.; Tsiomenko, A.; Varnai, P.; Balla, T.
A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1
Mol. Biol. Cell
16
1282-1295
2005
Homo sapiens
Pizarro-Cerda, J.; Payrastre, B.; Wang, Y.J.; Veiga, E.; Yin, H.L.; Cossart, P.
Type II phosphatidylinositol 4-kinases promote Listeria monocytogenes entry into target cells
Cell. Microbiol.
9
2381-2390
2007
Homo sapiens
Kakuk, A.; Friedlaender, E.; Vereb, G.; Kasa, A.; Balla, A.; Balla, T.; Heilmeyer, L.M.; Gergely, P.; Vereb, G.
Nucleolar localization of phosphatidylinositol 4-kinase PI4K230 in various mammalian cells
Cytometry A
69
1174-1183
2006
Homo sapiens, Rattus norvegicus
Szivak, I.; Lamb, N.; Heilmeyer, L.M.
Subcellular localization and structural function of endogenous phosphorylated phosphatidylinositol 4-kinase (PI4K92)
J. Biol. Chem.
281
16740-16749
2006
Homo sapiens
Toth, B.; Balla, A.; Ma, H.; Knight, Z.A.; Shokat, K.M.; Balla, T.
Phosphatidylinositol 4-kinase IIIbeta regulates the transport of ceramide between the endoplasmic reticulum and Golgi
J. Biol. Chem.
281
36369-36377
2006
Homo sapiens
Waugh, M.G.; Minogue, S.; Chotai, D.; Berditchevski, F.; Hsuan, J.J.
Lipid and peptide control of phosphatidylinositol 4-kinase IIalpha activity on Golgi-endosomal rafts
J. Biol. Chem.
281
3757-3763
2006
Homo sapiens
Jeganathan, S.; Lee, J.M.
Binding of elongation factor eEF1A2 to phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation
J. Biol. Chem.
282
372-380
2007
Homo sapiens
Minogue, S.; Waugh, M.G.; De Matteis, M.A.; Stephens, D.J.; Berditchevski, F.; Hsuan, J.J.
Phosphatidylinositol 4-kinase is required for endosomal trafficking and degradation of the EGF receptor
J. Cell Sci.
119
571-580
2006
Homo sapiens
Xiong, Z.M.; Kitagawa, K.; Nishiuchi, Y.; Kimura, T.; Inagaki, C.
Protective effects of Abeta-derived tripeptide, Abeta(32-34), on Abeta(1-42)-induced phosphatidylinositol 4-kinase inhibition and neurotoxicity
Neurosci. Lett.
419
247-252
2007
Homo sapiens
Delang, L.; Paeshuyse, J.; Neyts, J.
The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication
Biochem. Pharmacol.
84
1400-1408
2012
Homo sapiens
Szentpetery, Z.; Szakacs, G.; Bojjireddy, N.; Tai, A.W.; Balla, T.
Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIalpha
Biochim. Biophys. Acta
1811
476-483
2011
Homo sapiens
Waugh, M.G.
Phosphatidylinositol 4-kinases, phosphatidylinositol 4-phosphate and cancer
Cancer Lett.
325
125-131
2012
Homo sapiens
Moessinger, J.; Wieffer, M.; Krause, E.; Freund, C.; Gerth, F.; Krauss, M.; Haucke, V.
Phosphatidylinositol 4-kinase IIalpha function at endosomes is regulated by the ubiquitin ligase Itch
EMBO Rep.
13
1087-1094
2012
Homo sapiens
Jung, G.; Barylko, B.; Lu, D.; Shu, H.; Yin, H.; Albanesi, J.P.
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90
J. Biol. Chem.
286
12775-12784
2011
Homo sapiens, Rattus norvegicus
Yang, N.; Ma, P.; Lang, J.; Zhang, Y.; Deng, J.; Ju, X.; Zhang, G.; Jiang, C.
Phosphatidylinositol 4-kinase IIIbeta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry
J. Biol. Chem.
287
8457-8467
2012
Chlorocebus sabaeus, Homo sapiens
Berger, K.L.; Kelly, S.M.; Jordan, T.X.; Tartell, M.A.; Randall, G.
Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication
J. Virol.
85
8870-8883
2011
Homo sapiens
Banerji, S.; Ngo, M.; Lane, C.F.; Robinson, C.A.; Minogue, S.; Ridgway, N.D.
Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the Golgi apparatus requires phosphatidylinositol 4-kinase IIalpha
Mol. Biol. Cell
21
4141-4150
2010
Cricetulus griseus, Homo sapiens
Jovic, M.; Kean, M.J.; Szentpetery, Z.; Polevoy, G.; Gingras, A.C.; Brill, J.A.; Balla, T.
Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, beta-glucocerebrosidase
Mol. Biol. Cell
23
1533-1545
2012
Homo sapiens
Tai, A.W.; Salloum, S.
The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement
PLoS ONE
6
e26300
2011
Homo sapiens
Bianco, A.; Reghellin, V.; Donnici, L.; Fenu, S.; Alvarez, R.; Baruffa, C.; Peri, F.; Pagani, M.; Abrignani, S.; Neddermann, P.; De Francesco, R.
Metabolism of phosphatidylinositol 4-kinase IIIalpha-dependent PI4P is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity
PLoS Pathog.
8
e1002576
2012
Homo sapiens
Altan-Bonnet, N.; Balla, T.
Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms
Trends Biochem. Sci.
37
293-302
2012
Saccharomyces cerevisiae, Homo sapiens
Graham, T.R.; Burd, C.G.
Coordination of Golgi functions by phosphatidylinositol 4-kinases
Trends Cell Biol.
21
113-121
2011
Saccharomyces cerevisiae, Homo sapiens
Klima, M.; Baumlova, A.; Chalupska, D.; Hrebabecky, H.; Dejmek, M.; Nencka, R.; Boura, E.
The high-resolution crystal structure of phosphatidylinositol 4-kinase IIbeta and the crystal structure of phosphatidylinositol 4-kinase IIalpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design
Acta Crystallogr. Sect. D
71
1555-1563
2015
Homo sapiens (Q8TCG2), Homo sapiens (Q9BTU6)
Sinha, R.K.; Bojjireddy, N.; Kulkarni, D.; Ratheesh, A.; Chiplunkar, S.V.; Gude, R.; Subrahmanyam, G.
Type II phosphatidylinositol 4-kinase beta is an integral signaling component of early T cell activation mechanisms
Biochimie
95
1560-1566
2013
Homo sapiens
Baumlova, A.; Chalupska, D.; Rozycki, B.; Jovic, M.; Wisniewski, E.; Klima, M.; Dubankova, A.; Kloer, D.P.; Nencka, R.; Balla, T.; Boura, E.
The crystal structure of the phosphatidylinositol 4-kinase IIalpha
EMBO Rep.
15
1085-1092
2014
Homo sapiens (Q9BTU6)
Rutaganira, F.U.; Fowler, M.L.; McPhail, J.A.; Gelman, M.A.; Nguyen, K.; Xiong, A.; Dornan, G.L.; Tavshanjian, B.; Glenn, J.S.; Shokat, K.M.; Burke, J.E.
Design and structural characterization of potent and selective inhibitors of phosphatidylinositol 4 kinase IIIbeta
J. Med. Chem.
59
1830-1839
2016
Homo sapiens
Harak, C.; Radujkovic, D.; Taveneau, C.; Reiss, S.; Klein, R.; Bressanelli, S.; Lohmann, V.
Mapping of functional domains of the lipid kinase phosphatidylinositol 4-kinase type III alpha involved in enzymatic activity and hepatitis C virus replication
J. Virol.
88
9909-9926
2014
Homo sapiens
Ryder, P.V.; Vistein, R.; Gokhale, A.; Seaman, M.N.; Puthenveedu, M.A.; Faundez, V.
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIalpha
Mol. Biol. Cell
24
2269-2284
2013
Homo sapiens
Arita, M.; Dobrikov, G.; Puerstinger, G.; Galabov, A.S.
Allosteric Regulation of Phosphatidylinositol 4-Kinase III Beta by an Antipicornavirus Compound MDL-860
ACS Infect. Dis.
3
585-594
2017
Homo sapiens
Sala, M.; Koegler, M.; Plackova, P.; Mejdrova, I.; Hrebabecky, H.; Prochazkova, E.; Strunin, D.; Lee, G.; Birkus, G.; Weber, J.; Mertlikova-Kaiserova, H.; Nencka, R.
Purine analogs as phosphatidylinositol 4-kinase IIIbeta inhibitors
Bioorg. Med. Chem. Lett.
26
2706-2712
2016
Homo sapiens
Mohamed, M.; Gardeitchik, T.; Balasubramaniam, S.; Guerrero-Castillo, S.; Dalloyaux, D.; van Kraaij, S.; Venselaar, H.; Hoischen, A.; Urban, Z.; Brandt, U.; Al-Shawi, R.; Simons, J.P.; Frison, M.; Ngu, L.H.; Callewaert, B.; Spelbrink, H.; Kallemeijn, W.W.; Aerts, J.M.F.G.; Waugh, M.G.; Morava, E.; We, W.e.v.
Novel defect in phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) at the membrane-enzyme interface is associated with metabolic cutis laxa
J. Inherit. Metab. Dis.
43
1382-1391
2020
Homo sapiens
Sengupta, N.; Jovic, M.; Barnaeva, E.; Kim, D.W.; Hu, X.; Southall, N.; Dejmek, M.; Mejdrova, I.; Nencka, R.; Baumlova, A.; Chalupska, D.; Boura, E.; Ferrer, M.; Marugan, J.; Balla, T.
A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha
J. Lipid Res.
60
683-693
2019
Homo sapiens
Mejdrova, I.; Chalupska, D.; Plackova, P.; Mueller, C.; Sala, M.; Klima, M.; Baumlova, A.; Hrebabecky, H.; Prochazkova, E.; Dejmek, M.; Strunin, D.; Weber, J.; Lee, G.; Matousova, M.; Mertlikova-Kaiserova, H.; Ziebuhr, J.; Birkus, G.; Boura, E.; Nencka, R.
Rational design of novel highly potent and selective phosphatidylinositol 4-kinase IIIbeta (PI4KB) inhibitors as broad-spectrum antiviral agents and tools for chemical biology
J. Med. Chem.
60
100-118
2017
Homo sapiens, Homo sapiens (Q9UBF8)
Chalupska, D.; Eisenreichova, A.; Rozycki, B.; Rezabkova, L.; Humpolickova, J.; Klima, M.; Boura, E.
Structural analysis of phosphatidylinositol 4-kinase IIIbeta (PI4KB) - 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro
J. Struct. Biol.
200
36-44
2017
Homo sapiens (Q9UBF8)
Alli-Balogun, G.O.; Gewinner, C.A.; Jacobs, R.; Kriston-Vizi, J.; Waugh, M.G.; Minogue, S.
Phosphatidylinositol 4-kinase IIbeta negatively regulates invadopodia formation and suppresses an invasive cellular phenotype
Mol. Biol. Cell
27
4033-4042
2016
Homo sapiens
Daboussi, L.; Costaguta, G.; Ghukasyan, R.; Payne, G.S.
Conserved role for Gga proteins in phosphatidylinositol 4-kinase localization to the trans-Golgi network
Proc. Natl. Acad. Sci. USA
114
3433-3438
2017
Saccharomyces cerevisiae, Homo sapiens
