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Information on EC 2.7.1.40 - pyruvate kinase

for references in articles please use BRENDA:EC2.7.1.40

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IUBMB Comments

UTP, GTP, CTP, ITP and dATP can also act as donors. Also phosphorylates hydroxylamine and fluoride in the presence of CO2.

The enzyme appears in viruses and cellular organisms

Synonyms
pyruvate kinase, m2-pk, pyruvate kinase m2, l-pk, pyk, tum2-pk, pyruvate kinase type m2, liver pyruvate kinase, pyruvate kinase m2 isoform, m2-pyruvate kinase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + pyruvate = ADP + phosphoenolpyruvate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
1-butanol autotrophic biosynthesis (engineered), anaerobic energy metabolism (invertebrates, cytosol), Bifidobacterium shunt, Entner-Doudoroff pathway I, Entner-Doudoroff pathway II (non-phosphorylative), Entner-Doudoroff pathway III (semi-phosphorylative), glycerol degradation to butanol, glycolysis I (from glucose 6-phosphate), glycolysis II (from fructose 6-phosphate), glycolysis III (from glucose), glycolysis IV, glycolysis V (Pyrococcus), heterolactic fermentation, mixed acid fermentation, photosynthetic 3-hydroxybutanoate biosynthesis (engineered), Rubisco shunt, superpathway of glucose and xylose degradation
Highest Expressing Human Cell Lines
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