Reference on EC 2.7.1.107 - diacylglycerol kinase (ATP) and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schaap, D.; de Widt, J.; van der Wal, J.; Vandekerckhove, J.; van Damme, J.; Gussow, D.; Ploegh, H.L.; van Blitterswijk, W.J.; van der Bend, R.L.
Purification, cDNA-cloning and expression of human diacylglycerol kinase
FEBS Lett.
275
151-158
1990
Escherichia coli, Homo sapiens
Allan, D.; Thomas, P.; Gatt, S.
1,2-diacylglycerol kinase of human erythrocyte membranes. Assay with endogenously generated substrate
Biochem. J.
191
669-672
1980
Homo sapiens
Yada, Y.; Ozeki, T.; Kanoh, H.; Nozawa, Y.
Purification and characterization of cytosolic diacylglycerol kinases of human platelets
J. Biol. Chem.
265
19237-19243
1990
Homo sapiens
Yamada, K.; Sakane, F.; Imai, S.; Tsushima, S.; Murakami, T.; Kanoh, H.
Regulatory role of diacylglycerol kinase gamma in macrophage differentiation of leukemia cells
Biochem. Biophys. Res. Commun.
305
101-107
2003
Homo sapiens
Hurttia, H.; Leino, L.
Subcellular localization of diacylglycerol kinase activity in stimulated and unstimulated human peripheral blood lymphocytes and neutrophils
Biochem. Mol. Biol. Int.
40
579-585
1996
Homo sapiens
Tabellini, G.; Bortul, R.; Santi, S.; Riccio, M.; Baldini, G.; Cappellini, A.; Billi, A.M.; Berezney, R.; Ruggeri, A.; Cocco, L.; Martelli, A.M.
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus
Exp. Cell Res.
287
143-154
2003
Homo sapiens, Rattus norvegicus
Sakane, F.; Kanoh, H.
Molecules in focus: diacylglycerol kinase
Int. J. Biochem. Cell Biol.
29
1139-1143
1997
Homo sapiens, Mesocricetus auratus, Rattus norvegicus, Sus scrofa
Caricasole, A.; Bettini, E.; Sala, C.; Roncarati, R.; Kobayashi, N.; Caldara, F.; Goto, K.; Terstappen, G.C.
Molecular cloning and characterization of the human diacylglycerol kinase beta (DGKbeta) gene: alternative splicing generates DGKbeta isotypes with different properties
J. Biol. Chem.
277
4790-4796
2002
Homo sapiens (Q9Y6T7), Homo sapiens
Bunting, M.; Tang, W.; Zimmerman, G.A.; McIntyre, T.M.; Prescott, S.M.
Molecular cloning and characterization of a novel human diacylglycerol kinase zeta
J. Biol. Chem.
271
10230-10236
1996
Homo sapiens (Q13574), Homo sapiens
Yamada, K.; Sakane, F.; Matsushima, N.; Kanoh, H.
EF-hand motifs of alpha, beta and gamma isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes
Biochem. J.
321
59-64
1997
Homo sapiens, Rattus norvegicus, Sus scrofa, Sus scrofa DGKalpha
Ding, L.; Traer, E.; McIntyre, T.M.; Zimmerman, G.A.; Prescott, S.M.
The cloning and characterization of a novel human diacylglycerol kinase, DGKiota
J. Biol. Chem.
273
32746-32752
1998
Homo sapiens
Murakami, T.; Sakane, F.; Imai, S.; Houkin, K.; Kanoh, H.
Identification and characterization of two splice variants of human diacylglycerol kinase eta
J. Biol. Chem.
278
34364-34372
2003
Homo sapiens (Q86XP1), Homo sapiens
Los, A.P.; van Baal, J.; de Widt, J.; Divecha, N.; van Blitterswijk, W.J.
Structure-activity relationship of diacylglycerol kinase theta
Biochim. Biophys. Acta
1636
169-174
2004
Homo sapiens
Luo, B.; Regier, D.S.; Prescott, S.M.; Topham, M.K.
Diacylglycerol kinases
Cell. Signal.
16
983-989
2004
Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Mammalia, no activity in Saccharomyces cerevisiae
Dicu, A.O.; Matthew, K.; Topham, K.; Ottaway, L.; Epand, R.M.
Role of the hydrophobic segment of diacylglycerol kinase epsilon
Biochemistry
46
6109-6117
2007
Homo sapiens
Tu-Sekine, B.; Ostroski, M.; Raben, D.M.
Modulation of diacylglycerol kinase theta activity by alpha-thrombin and phospholipids
Biochemistry
46
924-932
2007
Homo sapiens
Yanagisawa, K.; Yasuda, S.; kai, M.; Imai, S.i.; Yamada, K.; Yamashita, T.; JImbow, K.; Kanoh, H.; Sakane, F.
Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation
Biochim. Biophys. Acta
1771
462-474
2007
Homo sapiens, Homo sapiens (P23743)
Los, A.P.; de Widt, J.; Topham, M.K.; van Blitterswijk, W.J.; Divecha, N.
Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein
Biochim. Biophys. Acta
1773
352-357
2007
Homo sapiens
Alonso, R.; Mazzeo, C.; Merida, I.; Izquierdo, M.
: A new role of diacylglycerol kinase alpha on the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes
Biochimie
89
213-221
2007
Homo sapiens, Homo sapiens (P23743)
Yasuda, S.; Kai, M.; Imai, S.; Kanoh, H.; Sakane, F.
Diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor
FEBS Lett.
581
551-557
2007
Chlorocebus aethiops, Homo sapiens (P49619)
Evangelisti, C.; Bortul, R.; Fala, F.; Tabellini, G.; Goto, K.; Martelli, A.M.
Nuclear diacylglycerol kinases: emerging downstream regulators in cell signalling networks
Histol. Histopathol.
22
573-579
2007
Chlorocebus aethiops, Cricetulus griseus, Homo sapiens, Mus musculus, Rattus norvegicus
Miele, C.; Paturzo, F.; Teperino, R.; Sakane, F.; Fiory, F.; Oriente, F.; Ungaro, P.; Valentino, R.; Beguinot, F.; Formisano, P.
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol kinase subcellular localization
J. Biol. Chem.
282
3185-3143
2007
Homo sapiens
Rincon, E.; Santos, T.; Avila-Flores, A.; Albar, J.P.; Lalioti, V.; Lei, C.; Hong, W.; Merida, I.
Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein
Mol. Cell. Proteomics
6
1073-1087
2007
Homo sapiens, Homo sapiens (Q13574)
Leach, N.T.; Sun, Y.; Michaud, S.; Zheng, Y.; Ligon, K.L.; Ligon, A.H.; Sander, T.; Korf, B.R.; Lu, W.; Harris, D.J.; Gusella, J.F.; Maas, R.L.; Quade, B.J.; Cole, A.J.; Kelz, M.B.; Morton, C.C.
Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice
Am. J. Hum. Genet.
80
792-799
2007
Mus musculus, Homo sapiens (Q16760), Homo sapiens
Filigheddu, N.; Cutrupi, S.; Porporato, P.E.; Riboni, F.; Baldanzi, G.; Chianale, F.; Fortina, E.; Piantanida, P.; De Bortoli, M.; Vacca, G.; Graziani, A.; Surico, N.
Diacylglycerol kinase is required for HGF-induced invasiveness and anchorage-independent growth of MDA-MB-231 breast cancer cells
Anticancer Res.
27
1489-1492
2007
Homo sapiens
Kawasaki, T.; Kobayashi, T.; Ueyama, T.; Shirai, Y.; Saito, N.
Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha
Biochem. J.
409
471-479
2008
Homo sapiens
Yasuda, S.; Kai, M.; Imai, S.; Kanoh, H.; Sakane, F.
Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin
Biochem. J.
409
95-106
2008
Homo sapiens
Epand, R.M.; Shulga, Y.V.; Timmons, H.C.; Perri, A.L.; Belani, J.D.; Perinpanathan, K.; Johnson-McIntire, L.B.; Bajjalieh, S.; Dicu, A.O.; Elias, C.; Rychnovsky, S.D.; Topham, M.K.
Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase
Biochemistry
46
14225-14231
2007
Homo sapiens
Glukhov, E.; Shulga, Y.V.; Epand, R.F.; Dicu, A.O.; Topham, M.K.; Deber, C.M.; Epand, R.M.
Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon
Biochim. Biophys. Acta
1768
2549-2558
2007
Homo sapiens (P52429)
Chibalin, A.V.; Leng, Y.; Vieira, E.; Krook, A.; Bjoernholm, M.; Long, Y.C.; Kotova, O.; Zhong, Z.; Sakane, F.; Steiler, T.; Nylen, C.; Wang, J.; Laakso, M.; Topham, M.K.; Gilbert, M.; Wallberg-Henriksson, H.; Zierath, J.R.
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance
Cell
132
375-386
2008
Mus musculus, Rattus norvegicus, Homo sapiens (Q16760), Homo sapiens
Williams, J.M.; Pettitt, T.R.; Powell, W.; Grove, J.; Savage, C.O.; Wakelam, M.J.
Antineutrophil cytoplasm antibody-stimulated neutrophil adhesion depends on diacylglycerol kinase-catalyzed phosphatidic acid formation
J. Am. Soc. Nephrol.
18
1112-1120
2007
Homo sapiens
Merino, E.; Avila-Flores, A.; Shirai, Y.; Moraga, I.; Saito, N.; Merida, I.
Lck-dependent tyrosine phosphorylation of diacylglycerol kinase alpha regulates its membrane association in T cells
J. Immunol.
180
5805-5815
2008
Homo sapiens (P23743)
Decaffmeyer, M.; Shulga, Y.V.; Dicu, A.O.; Thomas, A.; Truant, R.; Topham, M.K.; Brasseur, R.; Epand, R.M.
Determination of the topology of the hydrophobic segment of mammalian diacylglycerol kinase epsilon in a cell membrane and its relationship to predictions from modeling
J. Mol. Biol.
383
797-809
2008
Homo sapiens (P52429)
Li, D.; Urs, A.N.; Allegood, J.; Leon, A.; Merrill, A.H.; Sewer, M.B.
Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17
Mol. Cell. Biol.
27
6669-6685
2007
Homo sapiens
Baum, A.E.; Akula, N.; Cabanero, M.; Cardona, I.; Corona, W.; Klemens, B.; Schulze, T.G.; Cichon, S.; Rietschel, M.; Noethen, M.M.; Georgi, A.; Schumacher, J.; Schwarz, M.; Abou Jamra, R.; Hoefels, S.; Propping, P.; Satagopan, J.; Detera-Wadleigh, S.D.; Hardy, J.; McMahon, F.J.
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
Mol. Psychiatry
13
197-207
2008
Homo sapiens
Los, A.; de Widt, J.; van Blitterswijk, W.; Divecha, N.
Is there a role for diacylglycerol kinase-zeta in cell cycle regulation?
Adv. Enzyme Regul.
48
31-39
2008
Homo sapiens (Q13574)
Merida, I.; Avila-Flores, A.; Garcia, J.; Merino, E.; Almena, M.; Torres-Ayuso, P.
Diacylglycerol kinase alpha, from negative modulation of T cell activation to control of cancer progression
Adv. Enzyme Regul.
49
174-188
2009
Mus musculus (O88673), Homo sapiens (P23743)
Kai, M.; Yasuda, S.; Imai, S.; Toyota, M.; Kanoh, H.; Sakane, F.
Diacylglycerol kinase alpha enhances protein kinase Czeta-dependent phosphorylation at Ser311 of p65/RelA subunit of nuclear factor-kappaB
FEBS Lett.
583
3265-3268
2009
Sus scrofa (P20192), Homo sapiens (P23743)
Yasuda, S.; Kai, M.; Imai, S.; Takeishi, K.; Taketomi, A.; Toyota, M.; Kanoh, H.; Sakane, F.
Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization
J. Biol. Chem.
284
29559-29570
2009
Homo sapiens (Q86XP1)
Lung, M.; Shulga, Y.V.; Ivanova, P.T.; Myers, D.S.; Milne, S.B.; Brown, H.A.; Topham, M.K.; Epand, R.M.
Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol
J. Biol. Chem.
284
31062-31073
2009
Homo sapiens (P52429)
Gellett, A.M.; Kharel, Y.; Sunkara, M.; Morris, A.J.; Lynch, K.R.
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases
Biochem. Biophys. Res. Commun.
422
758-763
2012
Homo sapiens
Knight, M.J.; Joubert, M.K.; Plotkowski, M.L.; Kropat, J.; Gingery, M.; Sakane, F.; Merchant, S.S.; Bowie, J.U.
Zinc binding drives sheet formation by the SAM domain of diacylglycerol kinase delta
Biochemistry
49
9667-9676
2010
Homo sapiens
Gantayet, A.; Jegatheswaran, J.; Jayakumaran, G.; Topham, M.K.; Epand, R.M.
Endocannabinoids and diacylglycerol kinase activity
Biochim. Biophys. Acta
1808
1050-1053
2011
Homo sapiens (P52429), Homo sapiens (Q13574)
Takeuchi, M.; Sakiyama, S.; Usuki, T.; Sakai, H.; Sakane, F.
Diacylglycerol kinase delta1 transiently translocates to the plasma membrane in response to high glucose
Biochim. Biophys. Acta
1823
2210-2216
2012
Homo sapiens (Q16760), Homo sapiens
Prodeus, A.; Berno, B.; Topham, M.K.; Epand, R.M.
The basis of the substrate specificity of the epsilon isoform of human diacylglycerol kinase is not a consequence of competing hydrolysis of ATP
Chem. Phys. Lipids
166
26-30
2013
Homo sapiens (P52429), Homo sapiens
DSouza, K.; Epand, R.M.
Catalytic activity and acyl-chain selectivity of diacylglycerol kinase epsilon are modulated by residues in and near the lipoxygenase-like motif
J. Mol. Biol.
416
619-628
2012
Homo sapiens (P52429)
Gharbi, S.I.; Rincon, E.; Avila-Flores, A.; Torres-Ayuso, P.; Almena, M.; Cobos, M.A.; Albar, J.P.; Merida, I.
Diacylglycerol kinase zeta controls diacylglycerol metabolism at the immunological synapse
Mol. Biol. Cell
22
4406-4414
2011
Homo sapiens (P23743), Homo sapiens (Q13574)
Atsumi, H.; Kitada, M.; Kanasaki, K.; Koya, D.
Reversal of redox-dependent inhibition of diacylglycerol kinase by antioxidants in mesangial cells exposed to high glucose
Mol. Med. Rep.
4
923-927
2011
Homo sapiens
Sato, Y.; Murakami, C.; Yamaki, A.; Mizuno, S.; Sakai, H.; Sakane, F.
Distinct 1-monoacylglycerol and 2-monoacylglycerol kinase activities of diacylglycerol kinase isozymes
Biochim. Biophys. Acta
1864
1170-1176
2016
Homo sapiens (O75912), Homo sapiens (P49619), Homo sapiens (P52429), Homo sapiens (P52824), Homo sapiens (Q13574), Homo sapiens (Q16760), Homo sapiens (Q5KSL6), Homo sapiens (Q86XP1), Sus scrofa (P20192), Rattus norvegicus (P68403)
Saito, T.; Takahashi, D.; Sakane, F.
Expression, purification, and characterization of human diacylglycerol kinase zeta
ACS Omega
4
5540-5546
2019
Homo sapiens (Q13574), Homo sapiens
Merida, I.; Arranz-Nicolas, J.; Rodriguez-Rodriguez, C.; Avila-Flores, A.
Diacylglycerol kinase control of protein kinase C
Biochem. J.
476
1205-1219
2019
Homo sapiens (Q13574)
Jennings, W.; Doshi, S.; Hota, P.K.; Prodeus, A.; Black, S.; Epand, R.M.
Expression, purification, and properties of a human arachidonoyl-specific isoform of diacylglycerol kinase
Biochemistry
56
1337-1347
2017
Homo sapiens (P52429), Homo sapiens
Franks, C.E.; Campbell, S.T.; Purow, B.W.; Harris, T.E.; Hsu, K.L.
The ligand binding landscape of diacylglycerol kinases
Cell Chem. Biol.
24
870-880.e5
2017
Homo sapiens (P23743)
Epand, R.M.; So, V.; Jennings, W.; Khadka, B.; Gupta, R.S.; Lemaire, M.
Diacylglycerol kinase-epsilon properties and biological roles
Front. Cell Dev. Biol.
4
112
2016
Homo sapiens (P52429), Homo sapiens
Fazio, A.; Obeng, E.; Rusciano, I.; Marvi, M.; Zoli, M.; Mongiorgi, S.; Ramazzotti, G.; Follo, M.; McCubrey, J.; Cocco, L.; Manzoli, L.; Ratti, S.
Subcellular localization relevance and cancer-associated mechanisms of diacylglycerol kinases
Int. J. Mol. Sci.
21
1-19
2020
Homo sapiens (O75912), Homo sapiens (P23743), Homo sapiens (P49619), Homo sapiens (P52429), Homo sapiens (P52824), Homo sapiens (Q13574), Homo sapiens (Q16760), Homo sapiens (Q5KSL6), Homo sapiens (Q86XP1), Homo sapiens (Q9Y6T7)
Hayashi, D.; Tsumagari, R.; Liu, K.; Ueda, S.; Yamanoue, M.; Sakane, F.; Shirai, Y.
Screening of subtype-specific activators and inhibitors for diacylglycerol kinase
J. Biochem.
165
517-522
2019
Homo sapiens (O75912), Homo sapiens (P23743), Homo sapiens (P49619), Homo sapiens (P52824), Homo sapiens (Q13574), Homo sapiens (Q16760), Homo sapiens (Q5KSL6), Homo sapiens (Q86XP1), Homo sapiens (Q9Y6T7)
Poli, A.; Fiume, R.; Baldanzi, G.; Capello, D.; Ratti, S.; Gesi, M.; Manzoli, L.; Graziani, A.; Suh, P.G.; Cocco, L.; Follo, M.Y.
Nuclear localization of diacylglycerol kinase alpha in K562 cells is involved in cell cycle progression
J. Cell. Physiol.
232
2550-2557
2017
Homo sapiens (P23743), Homo sapiens
Takahashi, D.; Sakane, F.
Expression and purification of human diacylglycerol kinase alpha from baculovirus-infected insect cells for structural studies
PeerJ
6
e5449
2018
Homo sapiens (P23743), Homo sapiens
Murakami, E.; Shionoya, T.; Komenoi, S.; Suzuki, Y.; Sakane, F.
Cloning and characterization of novel testis-specific diacylglycerol kinase eta splice variants 3 and 4
PLoS ONE
11
e0162997
2016
Homo sapiens (Q86XP1)
