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Information on EC 2.6.1.94 - 2'-deamino-2'-hydroxyneamine transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.94 2'-deamino-2'-hydroxyneamine transaminase
IUBMB Comments
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of kanamycin A and kanamycin D. The enzyme, characterized from the bacterium Streptomyces kanamyceticus, can also catalyse EC 2.6.1.93, neamine transaminase.
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The expected taxonomic range for this enzyme is: Streptomyces kanamyceticus
Synonyms
6'-oxoparomamine aminotransferase, kacL, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2'-deamino-2'-hydroxyneamine + 2-oxoglutarate = 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate
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