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Information on EC 2.6.1.82 - putrescine-2-oxoglutarate transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.82 putrescine-2-oxoglutarate transaminase
IUBMB Comments
A pyridoxal 5'-phosphate protein . The product, 4-aminobutanal, spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.2.1.19, aminobutyraldehyde dehydrogenase. Cadaverine and spermidine can also act as substrates . Forms part of the arginine-catabolism pathway . cf. EC 2.6.1.113, putrescine---pyruvate transaminase.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
patase, putrescine transaminase, putrescine:2-oxoglutarate aminotransferase, putrescine-alpha-ketoglutarate transaminase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-aminobutanal = 1-pyrroline + H2O
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putrescine + 2-oxoglutarate = 1-pyrroline + L-glutamate + H2O
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overall reaction
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putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate
show the reaction diagram
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