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Information on EC 2.6.1.23 - 4-hydroxyglutamate transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.23 4-hydroxyglutamate transaminase
IUBMB Comments
The enzyme participates in a degradation pathway of trans-4-hydroxy-L-proline, a compound that contributes to the stability of the collagen triple helix. Oxaloacetate can replace 2-oxoglutarate. This enzyme may be identical with EC 2.6.1.1 aspartate transaminase.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
4-hydroxyglutamate aminotransferase, aminotransferase, 4-hydroxyglutamate, HGA, More, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
erythro-4-hydroxy-L-glutamate + 2-oxoglutarate = (4R)-4-hydroxy-2-oxoglutarate + L-glutamate
show the reaction diagram
oxaloacetate can replace 2-oxoglutarate
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