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Information on EC 2.5.1.75 - tRNA dimethylallyltransferase and Organism(s) Pseudomonas aeruginosa
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EC Tree 2 Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.75 tRNA dimethylallyltransferase
IUBMB Comments
Formerly known as tRNA isopentenyltransferase, but it is now known that prenyl diphosphate, rather than isopentenyl diphosphate, is the substrate.
The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms
The enzyme appears in selected viruses and cellular organisms
- 2.5.1.75
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prenylation
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farnesylation
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geranylgeranylated
-
isopentenylation
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isoprenoids
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geranyl
-
farnesyltransferase
-
ubiad1
-
geranylgeranyltransferase
-
isoprenylation
- isoprene
-
meroterpenoids
-
schnyder
-
neosartorya
-
polyprenyl
-
aspartate-rich
- ftase
- menaquinone-4
- undecaprenyl
- dimethylallyltryptophan
-
tryptophan-containing
- agriculture
- glyceollins
- medicine
- dmats
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nonsterol
- biotechnology
Reaction Schemes
show+
adenosine37 in tRNA
=
+
N6-(3-methylbut-2-en-1-yl)-adenosine37 in tRNA
Synonyms
prenyltransferase, trit1, trna isopentenyltransferase, trna-ipt, dmatase, trna ipt, mhipt3, noipt2, more
top
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
DELTA2-isopentenyl pyrophosphate:transfer ribonucleic acid DELTA2-isopentenyltransferase
-
-
-
-
DELTA2-isopentenyl pyrophosphate:tRNA-DELTA2-isopentenyl transferase
-
-
-
-
dimethylallyl-diphosphate:adenine37 in tRNA dimethylallyltransferase
-
-
-
-
isopentenyltransferase, transfer ribonucleate
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-
-
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transfer ribonucleate isopentenyltransferase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
alkenyl group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
cis-zeatin biosynthesis
SYSTEMATIC NAME
IUBMB Comments
prenyl-diphosphate:adenine37 in tRNA prenyltransferase
Formerly known as tRNA isopentenyltransferase, but it is now known that prenyl diphosphate, rather than isopentenyl diphosphate, is the substrate.
CAS REGISTRY NUMBER
COMMENTARY
37277-78-4
-
Highest Expressing Human Cell Lines
Cell Line LinksUNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). A0A367M1Q2_PSEAI
216
0
23383
TrEMBL
other Location (Reliability: 3)
EXTERNAL LINKS (specific for EC-Number 2.5.1.75)
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Release 2026.1 (March 2026)
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