Reference on EC 2.5.1.66 - N2-(2-carboxyethyl)arginine synthase
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tahlan, K.; Park, H.U.; Wong, A.; Beatty, P.H.; Jensen, S.E.
Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus
Antimicrob. Agents Chemother.
48
930-939
2004
Streptomyces clavuligerus (Q6TA05), Streptomyces clavuligerus
Liras, P.; Rodriguez-Garcia, A.
Clavulanic acid, a beta-lactamase inhibitor: biosynthesis and molecular genetics
Appl. Microbiol. Biotechnol.
54
467-475
2000
Streptomyces clavuligerus
Khaleeli, N.; Li, R.; Townsend, C.A.
Origin of the b-lactam carbons in clavulanic acid from an unusual thiamine pyrophosphate-mediated reaction
J. Am. Chem. Soc.
121
9223-9224
1999
Streptomyces clavuligerus
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Tahlan, K.; Anders, C.; Jensen, S.E.
The paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerus
J. Bacteriol.
186
6286-6297
2004
Streptomyces clavuligerus
Caines, M.E.C.; Elkins, J.M.; Hewitson, K.S.; Schofield, C.J.
Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway
J. Biol. Chem.
279
5685-5692
2004
Streptomyces clavuligerus
Gomez-Escribano, J.P.; Liras, P.; Pisabarro, A.; Martin, J.F.
An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus
Mol. Microbiol.
61
758-770
2006
Streptomyces clavuligerus
Caines, M.E.; Sorensen, J.L.; Schofield, C.J.
Structural and mechanistic studies on N(2)-(2-carboxyethyl)arginine synthase
Biochem. Biophys. Res. Commun.
385
512-517
2009
Streptomyces clavuligerus
Kwong, T.; Tahlan, K.; Anders, C.L.; Jensen, S.E.
Carboxyethylarginine synthase genes show complex cross-regulation in Streptomyces clavuligerus
Appl. Environ. Microbiol.
79
240-249
2013
Streptomyces clavuligerus (E2Q5Q8), Streptomyces clavuligerus (Q6TA05), Streptomyces clavuligerus
Shrestha, B.; Dhakal, D.; Darsandhari, S.; Pandey, R.; Pokhrel, A.; Jnawali, H.; Sohng, J.
Heterologous production of clavulanic acid intermediates in Streptomyces venezuelae
Biotechnol. Bioprocess Eng.
22
359-365
2017
Streptomyces clavuligerus, Streptomyces clavuligerus (E2Q5Q8)
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