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Information on EC 2.5.1.54 - 3-deoxy-7-phosphoheptulonate synthase and Organism(s) Pseudomonas aeruginosa

for references in articles please use BRENDA:EC2.5.1.54

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The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The enzyme appears in selected viruses and cellular organisms

Synonyms
dahp synthase, dahps, dah7ps, 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase, ds-co, ds-mn, dah7p synthase, dahp synthase-phe, 3-deoxy-d-arabinoheptulosonate 7-phosphate synthase, dah7p, more

SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-dehydro-3-deoxy-D-arabino-heptonate-7-phosphate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)
-
-
-
-
2-dehydro-3-deoxy-phosphoheptanoate aldolase
-
-
-
-
2-dehydro-3-deoxy-phosphoheptonate aldolase
-
-
-
-
2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase
-
-
-
-
3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase
-
-
-
-
3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase
-
-
-
-
3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase
-
-
-
-
3-deoxy-D-arabino-heptulosonate-7-phosphate synthase
-
-
-
-
7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)
-
-
-
-
7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating)
-
-
-
-
aldolase, phospho-2-keto-3-deoxyheptanoate
-
-
-
-
D-erythrose-4-phosphate-lyase
-
-
-
-
D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)
-
-
-
-
DAH7-P synthase
-
-
-
-
DAH7-P synthase (phe)
-
-
-
-
DAHP synthase
-
-
-
-
DAHP synthase-phe
-
-
-
-
DAHP synthase-trp
-
-
-
-
DAHP synthase-tyr
-
-
-
-
DAHP(Phe)
-
-
-
-
deoxy-D-arabino-heptulosonate-7-phosphate synthetase
-
-
-
-
KDPH synthase
-
-
-
-
KDPH synthetase
-
-
-
-
phospho-2-dehydro-3-deoxyheptonate aldolase
-
-
-
-
phospho-2-keto-3-deoxyheptanoate aldolase
-
-
-
-
Phospho-2-keto-3-deoxyheptonate aldolase
-
-
-
-
phospho-2-keto-3-deoxyheptonic aldolase
-
-
-
-
phospho-2-oxo-3-deoxyheptonate aldolase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
condensation
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
3-dehydroquinate biosynthesis I
SYSTEMATIC NAME
IUBMB Comments
phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)
-
CAS REGISTRY NUMBER
COMMENTARY hide
9026-94-2
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
show the reaction diagram
-
Substrates: -
Products: -
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate
show the reaction diagram
Substrates: -
Products: -
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
chorismate
-
competitive against phosphoenolpyruvate, noncompetitive against D-erythrose 4-phosphate; DAHP synthase-trp
phenylpyruvate
-
DAHP synthase-tyr
Trp
-
DAHP synthase-trp; non-competitive against phosphoenolpyruvate and competitive for D-erythrose 4-phosphate; Trp-sensitive isozyme
Tyr
-
DAHP synthase-tyr; L-Tyr; Tyr-sensitive isozyme
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.016 - 1
D-erythrose 4-phosphate
0.017 - 1.11
phosphoenolpyruvate
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
19.8
D-erythrose 4-phosphate
pH 7.5, 37Ā°C, presence of Co2+
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1160
D-erythrose 4-phosphate
pH 7.5, 37Ā°C, presence of Co2+
1240
phosphoenolpyruvate
pH 7.5, 37Ā°C, presence of Co2+
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.35 - 2.25
chorismate
1.35 - 2.55
phenylpyruvate
0.005 - 0.04
Trp
0.023
Tyr
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.005
-
partially purified isozyme synthase-trp
0.056
-
partially purified isozyme synthase-tyr
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.8
-
DAHP synthase-tyr
7.2
-
DAHP synthase-trp
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
top print hide Go to Organism Search
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Highest Expressing Human Cell Lines
Cell Line Links Gene Links
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A8G4E473_PSEAI
348
0
37984
TrEMBL
-
A0A7M2ZKP6_PSEAI
405
0
44342
TrEMBL
-
A0A8G8GSR3_PSEAI
448
0
49911
TrEMBL
-
A0A8G6RC76_PSEAI
217
0
23536
TrEMBL
-
A0A8G4FFL9_PSEAI
341
0
37142
TrEMBL
-
A0A8G5ZAM4_PSEAI
405
0
44302
TrEMBL
-
A0A8G4TT83_PSEAI
260
0
29060
TrEMBL
-
A0A509J7A3_PSEAI
233
0
26102
TrEMBL
-
A0A8G5UF21_PSEAI
334
0
36326
TrEMBL
-
A0A8G3HFY3_PSEAI
378
0
41540
TrEMBL
-
A0A8G6F2W5_PSEAI
401
0
43845
TrEMBL
-
A0A8G4K018_PSEAI
448
0
49833
TrEMBL
-
A0A367LY30_PSEAI
150
0
16745
TrEMBL
-
A0A8G5TFM4_PSEAI
351
0
38324
TrEMBL
-
A0A0A8RDE3_PSEAI
448
0
49850
TrEMBL
-
A0A8G7K6P7_PSEAI
55
0
6202
TrEMBL
-
A0A8G2Z4J3_PSEAI
109
0
12052
TrEMBL
-
A0A8G6NZ30_PSEAI
229
0
25532
TrEMBL
-
A0A8G3LL26_PSEAI
97
0
10749
TrEMBL
-
A0A659B9V9_PSEAI
348
0
37977
TrEMBL
-
A3RF12_PSEAI
274
0
29791
TrEMBL
-
G3XCJ9_PSEAI
405
0
44328
TrEMBL
-
A0A8G6ARQ9_PSEAI
189
0
20923
TrEMBL
-
A0A8G5QX77_PSEAI
65
0
7215
TrEMBL
-
A0A8G6CA89_PSEAI
354
0
38619
TrEMBL
-
A0A8G5Q8Z2_PSEAI
358
0
39129
TrEMBL
-
A0A8G7I580_PSEAI
364
0
38521
TrEMBL
-
A0A8G1JH73_PSEAI
405
0
44356
TrEMBL
-
A0A8G2YXL5_PSEAI
364
0
38757
TrEMBL
-
A0A8G6G7C1_PSEAI
404
0
44214
TrEMBL
-
A0A8G4V9J2_PSEAI
333
0
36222
TrEMBL
-
A0A4P0UCE7_PSEAI
348
0
39191
TrEMBL
-
A0A367LXK9_PSEAI
79
0
8841
TrEMBL
-
A0A8G4A8W7_PSEAI
364
0
38643
TrEMBL
-
A0A8G2V6V6_PSEAI
364
0
38556
TrEMBL
-
A0A8G4KUU2_PSEAI
163
0
18034
TrEMBL
-
A0A8G7GSY7_PSEAI
448
0
49837
TrEMBL
-
A0A659BJN0_PSEAI
364
0
38739
TrEMBL
-
A0A8G4XVW2_PSEAI
226
0
25406
TrEMBL
-
A0A8G3MKT1_PSEAI
60
0
6729
TrEMBL
-
A0A8G4DQ66_PSEAI
448
0
49793
TrEMBL
-
A0A8G6SN11_PSEAI
234
0
26001
TrEMBL
-
A0A8G3CZZ9_PSEAI
448
0
49910
TrEMBL
-
A0A8G7H6U1_PSEAI
405
0
44326
TrEMBL
-
A0A8G3CXW9_PSEAI
364
0
38709
TrEMBL
-
A0A8G5H628_PSEAI
364
0
38658
TrEMBL
-
A0A8B5A0C5_PSEAI
129
0
14237
TrEMBL
-
A0A8G2YB00_PSEAI
351
0
38213
TrEMBL
-
A0A8G6D8K7_PSEAI
448
0
49863
TrEMBL
-
A0A8G6UGT5_PSEAI
188
0
20810
TrEMBL
-
A0A8G7CWK7_PSEAI
159
0
17616
TrEMBL
-
A0A8G4XVS7_PSEAI
405
0
44350
TrEMBL
-
A0A8G4F9Z6_PSEAI
538
0
59777
TrEMBL
-
A0A8G6BUT8_PSEAI
143
0
15766
TrEMBL
-
A0A8G6XN90_PSEAI
324
0
35314
TrEMBL
-
A0A8G3EVC6_PSEAI
160
0
17718
TrEMBL
-
A0A8G3KDE2_PSEAI
362
0
39399
TrEMBL
-
A0A3S0JIN7_PSEAI
358
0
39067
TrEMBL
-
A0A2R3IPV9_PSEAI
358
0
39097
TrEMBL
-
A0A8F9JQG1_PSEAI
405
0
44343
TrEMBL
-
A0A8G2XIM7_PSEAI
405
0
44316
TrEMBL
-
A0A8B5BBL9_PSEAI
361
0
39280
TrEMBL
-
A0A8G4YU43_PSEAI
147
0
16180
TrEMBL
-
A0A8G2R911_PSEAI
364
0
38757
TrEMBL
-
A0A4P0TKR2_PSEAI
183
0
19585
TrEMBL
-
A0A8G2VIH8_PSEAI
448
0
49897
TrEMBL
-
A0A485I730_PSEAI
210
0
22702
TrEMBL
-
A3RF13_PSEAI
274
0
29847
TrEMBL
-
A0A8G5SKN3_PSEAI
358
0
39156
TrEMBL
-
A0A8G5FCF8_PSEAI
212
0
23825
TrEMBL
-
A0A8G3XVU5_PSEAI
142
0
15637
TrEMBL
-
A0A8G5K884_PSEAI
204
0
22858
TrEMBL
-
A0A8G3PHQ5_PSEAI
164
0
18233
TrEMBL
-
A0A8G2QNH7_PSEAI
405
0
44334
TrEMBL
-
A0A8G6V841_PSEAI
448
0
49867
TrEMBL
-
A0A8G4ZBI4_PSEAI
487
0
52505
TrEMBL
-
A0A367LX02_PSEAI
38
0
4413
TrEMBL
-
A0A8G3H807_PSEAI
280
0
30577
TrEMBL
-
A0A8G2RYT5_PSEAI
448
0
49882
TrEMBL
-
A0A8G3AJ05_PSEAI
405
0
44368
TrEMBL
-
A0A8G3CA29_PSEAI
339
0
37015
TrEMBL
-
A0A8G1QCV7_PSEAI
364
0
38761
TrEMBL
-
A0A8G5L0H6_PSEAI
361
0
39491
TrEMBL
-
A0A8G5M6U1_PSEAI
342
0
37295
TrEMBL
-
A0A4P0V8V4_PSEAI
334
0
36331
TrEMBL
-
A0A5K1SHJ6_PSEAI
448
0
49839
TrEMBL
-
A0A0K3ABT3_PSEAI
448
0
49851
TrEMBL
-
A0A8G2U8H0_PSEAI
364
0
38777
TrEMBL
-
A0A8G6WJE7_PSEAI
155
0
17186
TrEMBL
-
A0A643INA2_PSEAI
142
0
15826
TrEMBL
-
A0A8G7CBQ3_PSEAI
364
0
38718
TrEMBL
-
A0A8G3AE62_PSEAI
448
0
49768
TrEMBL
-
A0A8G7FVL1_PSEAI
61
0
6828
TrEMBL
-
A0A8G5A9R3_PSEAI
487
0
52621
TrEMBL
-
A0A8G2QPE1_PSEAI
342
0
37246
TrEMBL
-
A0A8F9NV79_PSEAI
448
0
49823
TrEMBL
-
A0A8G5D9C4_PSEAI
405
0
44280
TrEMBL
-
A0A8F9KW81_PSEAI
364
0
38757
TrEMBL
-
A0A8G7MH29_PSEAI
81
0
9025
TrEMBL
-
A0A8G7MVN3_PSEAI
448
0
49904
TrEMBL
-
A0A8G5G539_PSEAI
210
0
23572
TrEMBL
-
A0A8G5V5W8_PSEAI
80
0
8869
TrEMBL
-
A0A8B5ARR8_PSEAI
487
0
52524
TrEMBL
-
A0A8G3IGX9_PSEAI
89
0
9863
TrEMBL
-
A0A8G2JXN8_PSEAI
405
0
44340
TrEMBL
-
A0A8G3RSV6_PSEAI
315
0
34925
TrEMBL
-
A0A8G6EC85_PSEAI
85
0
9395
TrEMBL
-
A0A8G7Q1B4_PSEAI
196
0
21775
TrEMBL
-
A0A8G7S0Y4_PSEAI
364
0
38698
TrEMBL
-
A0A8G3SFR5_PSEAI
262
0
28580
TrEMBL
-
A0A8G7K6W7_PSEAI
405
0
44340
TrEMBL
-
A0A8G3SYN6_PSEAI
405
0
44254
TrEMBL
-
A0A8G4T8R6_PSEAI
155
0
17145
TrEMBL
-
A0A3M5E6E7_PSEAI
362
0
39562
TrEMBL
-
A0A072ZHU5_PSEAI
358
0
39142
TrEMBL
-
A0A8G3P1U2_PSEAI
76
0
8456
TrEMBL
-
A0A1B2AS07_PSEAI
405
0
44270
TrEMBL
-
A0A8G3J095_PSEAI
405
0
44368
TrEMBL
-
A0A8G4XC16_PSEAI
487
0
52580
TrEMBL
-
A0A7M2ZLS0_PSEAI
94
0
10332
TrEMBL
-
A0A4P0V952_PSEAI
104
0
10814
TrEMBL
-
A0A8G5L2I3_PSEAI
126
0
13724
TrEMBL
-
A0A643IVY7_PSEAI
141
0
14846
TrEMBL
-
A0A8G5CEE2_PSEAI
487
0
52513
TrEMBL
-
A0A0A7EBJ1_PSEAI
262
0
28700
TrEMBL
-
A0A8G3BJT0_PSEAI
160
0
17675
TrEMBL
-
A0A7M3B5F8_PSEAI
364
0
38586
TrEMBL
-
A0A3S0LX26_PSEAI
364
0
38461
TrEMBL
-
A0A8B5B990_PSEAI
212
0
23531
TrEMBL
-
A0A8G3NQZ9_PSEAI
364
0
38761
TrEMBL
-
A0A8G4I9F4_PSEAI
53
0
6032
TrEMBL
-
A0A8G3A3R5_PSEAI
93
0
10176
TrEMBL
-
A0A8G5MEU2_PSEAI
448
0
49793
TrEMBL
-
A0A8G3JYV2_PSEAI
169
0
18630
TrEMBL
-
A0A8G4GPI6_PSEAI
136
0
14972
TrEMBL
-
A0A8G2WFZ2_PSEAI
448
0
49806
TrEMBL
-
A0A8G6TEA3_PSEAI
97
0
10573
TrEMBL
-
A0A8B5BE73_PSEAI
364
0
38742
TrEMBL
-
A0A8G3UE20_PSEAI
405
0
44350
TrEMBL
-
A0A643INI4_PSEAI
84
0
9032
TrEMBL
-
A0A8G2PTX4_PSEAI
158
0
17491
TrEMBL
-
A0A8G4UEA3_PSEAI
340
0
36991
TrEMBL
-
A0A8G6YVE6_PSEAI
448
0
49899
TrEMBL
-
A0A1C6ZGW9_PSEAI
405
0
44312
TrEMBL
-
A0A8G8ERC4_PSEAI
392
0
42759
TrEMBL
-
A0A8G6Z692_PSEAI
166
0
18483
TrEMBL
-
A0A069QBC0_PSEAI
364
0
38743
TrEMBL
-
A0A8B5A937_PSEAI
129
0
14179
TrEMBL
-
A0A140SET9_PSEAI
364
0
38614
TrEMBL
-
A0A8G2RVV6_PSEAI
364
0
38674
TrEMBL
-
A0A8G4QZM4_PSEAI
356
0
38942
TrEMBL
-
A0A7M3APJ4_PSEAI
405
0
44326
TrEMBL
-
A0A8G6YB47_PSEAI
405
0
44300
TrEMBL
-
A0A8G6LAC2_PSEAI
91
0
9991
TrEMBL
-
A0A8G5TBR0_PSEAI
140
0
15429
TrEMBL
-
A0A8G6LTS5_PSEAI
239
0
26504
TrEMBL
-
A0A8G7AJI8_PSEAI
344
0
37518
TrEMBL
-
A0A367M304_PSEAI
154
0
16847
TrEMBL
-
A0A4P0UCK5_PSEAI
128
0
14314
TrEMBL
-
A0A8G4V771_PSEAI
358
0
39097
TrEMBL
-
A0A8G4YVZ5_PSEAI
161
0
17832
TrEMBL
-
A0A8G4EUK0_PSEAI
151
0
16774
TrEMBL
-
A0A8B4ZRP0_PSEAI
374
0
40640
TrEMBL
-
A0A8B5AUB8_PSEAI
163
0
18077
TrEMBL
-
A0A485F434_PSEAI
405
0
44256
TrEMBL
-
A0A8G3CPT1_PSEAI
137
0
15170
TrEMBL
-
A0A8G4W4U7_PSEAI
487
0
52499
TrEMBL
-
A0A8G7DVR1_PSEAI
56
0
6358
TrEMBL
-
A0A8G5SV75_PSEAI
218
0
24541
TrEMBL
-
A0A8G5THH4_PSEAI
82
0
9040
TrEMBL
-
A0A8G6AXW7_PSEAI
358
0
39140
TrEMBL
-
A0A8G3S7X6_PSEAI
487
0
52525
TrEMBL
-
A0A6A9JTA4_PSEAI
364
0
38686
TrEMBL
-
A0A2R3IPH2_PSEAI
364
0
38461
TrEMBL
-
A0A8G7F8K8_PSEAI
101
0
11082
TrEMBL
-
A0A8G2XM26_PSEAI
137
0
15085
TrEMBL
-
A0A8H1AIC4_PSEAI
364
0
38614
TrEMBL
-
A0A8F9PB59_PSEAI
358
0
39113
TrEMBL
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A0A0F6UCL6_PSEAI
364
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38713
TrEMBL
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A0A8G5KGR4_PSEAI
99
0
10841
TrEMBL
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A0A8G4VXG5_PSEAI
341
0
37139
TrEMBL
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A0A8G6A611_PSEAI
178
0
19641
TrEMBL
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A0A3M5DWS7_PSEAI
112
0
11935
TrEMBL
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A0A8G5GFN9_PSEAI
372
0
40727
TrEMBL