Reference on EC 2.5.1.34 - 4-dimethylallyltryptophan synthase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lee, S.L.; Floss, H.G.; Heinstein, P.
Purification and properties of dimethylallylpyrophosphate:tryptophan dimethylallyl transferase, the first enzyme of ergot alkaloid biosynthesis in Claviceps. sp. SD 58
Arch. Biochem. Biophys.
177
84-94
1976
Claviceps sp., Claviceps sp. SD58
Shibuya, M.; Chou, H.M.; Fountoulakis, M.; Hassam, S.; Kim, S.U.; Kobayashi, K.; Otsuka, H.; Rogalska, E.; Cassady, J.M.; Floss, H.G.
Stereochemistry of the isoprenylation of tryptophan catalyzed by 4-(gamma,gamma-dimethylallyl)tryptophan synthase from Claviceps, the first pathway-specific enzyme in ergot alkaloid biosynthesis
J. Am. Chem. Soc.
112
297-304
1990
Claviceps sp.
-
Rilling, H.C.
Dimethylallylpyrophosphate: L-tryptophan dimethylallyltransferase
Methods Enzymol.
110
335-340
1985
Claviceps sp., Claviceps sp. SD58
Gebler, J.C.; Poulter, C.D.
Purification and characterization of dimethylallyl tryptophan synthase from Claviceps purpurea
Arch. Biochem. Biophys.
296
308-313
1992
Claviceps purpurea
Cress, W.A.; Chayet, L.T.; Rilling, H.C.
Crystallization and partial characterization of dimethylallyl pyrophosphate: L-tryptophan dimethylallyltransferase from Claviceps sp. SD58
J. Biol. Chem.
256
10917-10923
1981
Claviceps sp., Claviceps sp. SD58
Tsai, H.F.; Wang, H.; Gebler, J.C.; Poulter, C.D.; Schardl, C.L.
The Claviceps purpurea gene encoding dimethylallyltryptophan synthase, the committed step for ergot alkaloid biosynthesis
Biochem. Biophys. Res. Commun.
216
119-125
1995
Claviceps purpurea
Unsoeld, I.A.; Li, S.M.
Overproduction, purification and characterization of FgaPT2, a dimethylallyltryptophan synthase from Aspergillus fumigatus
Microbiology
151
1499-1505
2005
Aspergillus fumigatus (Q50EL0), Aspergillus fumigatus
Steffan, N.; Unsoeld, I.A.; Li, S.M.
Chemoenzymatic synthesis of prenylated indole derivatives by using a 4-dimethylallyltryptophan synthase from Aspergillus fumigatus
ChemBioChem
8
1298-1307
2007
Aspergillus fumigatus
Kremer, A.; Li, S.M.
Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives
Appl. Microbiol. Biotechnol.
79
951-961
2008
Aspergillus fumigatus, Aspergillus fumigatus (Q50EL0)
Ding, Y.; Williams, R.M.; Sherman, D.H.
Molecular analysis of a 4-dimethylallyltryptophan synthase from Malbranchea aurantiaca
J. Biol. Chem.
283
16068-16076
2008
Malbranchea aurantiaca (B1A4C4), Malbranchea aurantiaca
Steffan, N.; Li, S.M.
Increasing structure diversity of prenylated diketopiperazine derivatives by using a 4-dimethylallyltryptophan synthase
Arch. Microbiol.
191
461-466
2009
Aspergillus fumigatus
Ruan, H.L.; Stec, E.; Li, S.M.
Production of diprenylated indole derivatives by tandem incubation of two recombinant dimethylallyltryptophan synthases
Arch. Microbiol.
191
791-795
2009
Aspergillus fumigatus
Luk, L.Y.; Tanner, M.E.
Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction
J. Am. Chem. Soc.
131
13932-13933
2009
Aspergillus fumigatus
Metzger, U.; Schall, C.; Zocher, G.; Unsoeld, I.; Stec, E.; Li, S.M.; Heide, L.; Stehle, T.
The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria
Proc. Natl. Acad. Sci. USA
106
14309-14314
2009
Aspergillus fumigatus
Schwarzer, D.; Gritsch, P.; Gaich, T.
Mimicking dimethylallyltryptophan synthase: experimental evidence for a biosynthetic cope rearrangement process
Angew. Chem. Int. Ed. Engl.
51
11514-11516
2012
Claviceps purpurea
Yu, X.; Xie, X.; Li, S.M.
Substrate promiscuity of secondary metabolite enzymes: prenylation of hydroxynaphthalenes by fungal indole prenyltransferases
Appl. Microbiol. Biotechnol.
92
737-748
2011
Aspergillus fumigatus
Luk, L.Y.; Qian, Q.; Tanner, M.E.
A cope rearrangement in the reaction catalyzed by dimethylallyltryptophan synthase?
J. Am. Chem. Soc.
133
12342-12345
2011
Aspergillus fumigatus
Rudolf, J.D.; Wang, H.; Poulter, C.D.
Multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase
J. Am. Chem. Soc.
135
1895-1902
2013
Claviceps purpurea, Claviceps purpurea (M1WA41)
Yu, X.; Li, S.M.
Prenyltransferases of the dimethylallyltryptophan synthase superfamily
Methods Enzymol.
516
259-278
2012
Aspergillus fumigatus, Claviceps purpurea, Malbranchea aurantiaca
Liebhold, M.; Xie, X.; Li, S.M.
Expansion of enzymatic Friedel-Crafts alkylation on indoles: acceptance of unnatural beta-unsaturated allyl diphospates by dimethylallyl-tryptophan synthases
Org. Lett.
14
4882-4885
2012
Aspergillus fumigatus
Mahmoodi, N.; Qian, Q.; Luk, L.; Tanner, M.
Rearrangements in the mechanisms of the indole alkaloid prenyltransferases
Pure Appl. Chem.
85
1935-1948
2013
Aspergillus fumigatus (Q50EL0)
-
Mai, P.; Zocher, G.; Ludwig, L.; Stehle, T.; Li, S.
Actions of tryptophan prenyltransferases toward fumiquinazolines and their potential application for the generation of prenylated derivatives by combining chemical and chemoenzymatic syntheses
Adv. Synth. Catal.
358
1639 -1653
2016
Aspergillus fumigatus (Q50EL0)
-
Fan, A.; Winkelblech, J.; Li, S.M.
Impacts and perspectives of prenyltransferases of the DMATS superfamily for use in biotechnology
Appl. Microbiol. Biotechnol.
99
7399-7415
2015
Aspergillus fumigatus (Q50EL0)
Miyamoto, K.; Ishikawa, F.; Nakamura, S.; Hayashi, Y.; Nakanishi, I.; Kakeya, H.
A 7-dimethylallyl tryptophan synthase from a fungal Neosartorya sp.: biochemical characterization and structural insight into the regioselective prenylation
Bioorg. Med. Chem.
22
2517-2528
2014
Aspergillus fumigatus (Q50EL0), Aspergillus fumigatus
Fan, A.; Zocher, G.; Stec, E.; Stehle, T.; Li, S.M.
Site-directed mutagenesis switching a dimethylallyl tryptophan synthase to a specific tyrosine C3-prenylating enzyme
J. Biol. Chem.
290
1364-1373
2015
Aspergillus fumigatus (Q50EL0), Aspergillus fumigatus
Fan, A.; Xie, X.; Li, S.M.
Tryptophan prenyltransferases showing higher catalytic activities for Friedel-Crafts alkylation of o- and m-tyrosines than tyrosine prenyltransferases
Org. Biomol. Chem.
13
7551-7557
2015
Aspergillus fumigatus (Q50EL0)
Fan, A.; Li, S.M.
Saturation mutagenesis on Arg244 of the tryptophan C4-prenyltransferase FgaPT2 leads to enhanced catalytic ability and different preferences for tryptophan-containing cyclic dipeptides
Appl. Microbiol. Biotechnol.
100
5389-5399
2016
Aspergillus fumigatus (Q50EL0), Aspergillus fumigatus, Aspergillus fumigatus ATCC MYA-4609 (Q50EL0)
Fernandez-Bodega, A.; Alvarez-Alvarez, R.; Liras, P.; Martin, J.F.
Silencing of a second dimethylallyltryptophan synthase of Penicillium roqueforti reveals a novel clavine alkaloid gene cluster
Appl. Microbiol. Biotechnol.
101
6111-6121
2017
Penicillium roqueforti, Penicillium roqueforti ATCC 10110
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