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BRENDA support

Information on EC 2.5.1.146 - 3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase

for references in articles please use BRENDA:EC2.5.1.146

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IUBMB Comments

The enzyme, characterized from the cyanobacterium Fischerella ambigua UTEX 1903, participates in the biosynthesis of hapalindole-type alkaloids.

The expected taxonomic range for this enzyme is: Fischerella ambigua

Synonyms
famd2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranyl diphosphate + 3-[(Z)-2-isocyanoethenyl]-1H-indole = 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + diphosphate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
12-epi-fischerindole biosynthesis, 12-epi-hapalindole biosynthesis, hapalindole H biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links